Birkle
James Birkle, Redwood City, CA US
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20100050571 | Method And Apparatus For Inflating And Sealing Packing Cushions With Rotary Sealing Mechanism - An apparatus for inflating and sealing packing cushions has a drive mechanism for feeding a preconfigured film material to a sealing mechanism in a flattened state without wrinkles in the sealing region in which a longitudinal seal is formed. In one aspect, the drive mechanism comprises a pair of upper adjacent belts and a backing element, such as a lower belt. The sealing mechanism may be a rotary sealing wheel that contacts the film material between the upper adjacent belts. | 03-04-2010 |
20130032293 | METHOD AND APPARATUS FOR INFLATING AND SEALING PACKING CUSHIONS WITH ROTARY SEALING MECHANISM - An apparatus for inflating and sealing packing cushions has a drive mechanism for feeding a preconfigured film material to a sealing mechanism in a flattened state without wrinkles in the sealing region in which a longitudinal seal is formed. A feed mechanism includes a drive mechanism for advancing the film along a path, a first guide member which contacts a first surface of the film material in a first longitudinal region, and a second guide member which contacts the first surface of the film material in a second longitudinal region laterally offset from and parallel to the first longitudinal region. In some embodiments, the first and second guide members are adjacent belts. In other embodiments, the first and second guide members are stationary guide members or “skis.” The sealing mechanism may include a rotary sealing element and opposed backing element, such as a belt or a wheel. | 02-07-2013 |
Jochen Birkle, Tettnang DE
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20090298647 | HYDRAULIC CIRCUIT ARRANGEMENT FOR OPERATING A HYDRODYNAMIC TORQUE CONVERTER - A hydraulic circuit arrangement for operating a hydrodynamic torque converter ( | 12-03-2009 |
Siegfried Birkle, Höchstadt DE
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20090130658 | Arrangement for integrated and automated dna or protein analysis in a single-use cartridge, method for producing such a cartridge and operating method for dna or protein analysis using such a cartridge - A cartridge (card) having a system of microchannels and/or microcavities is used for automated DNA or protein analysis. In at least one embodiment, the microchannels or microcavities include geometrical structures for receiving dry reagents. For the purpose of industrial production, the cartridge is produced from a flat card support, e.g., by injection moulding. The reagents are spotted into the open channels, dried and then the channels are sealed by way of a film. A finished cartridge can thus be provided with a test sample and the fully automated measuring sequence can be initiated by inserting said cartridge into a read-out device. | 05-21-2009 |
20090136922 | Method for carrying out an electrochemical measurement on a liquid measuring sample in a measuring chamber that can be accessed by lines, and corresponding arrangement - Especially in order to carry out the so-called enzyme-coupled DNA hybridisation test in a closed cartridge including a microfluid system, using stored dry reagents, the reagents must be dissolved in the microfluid system and transported into the measuring chamber directly before the measurement. During the dissolution of the reagents in water, air cushions that cannot reach the measuring chamber must absolutely be prevented from forming upstream of the reagent liquid. According to an embodiment of the invention, the liquid measuring sample and the liquid reagents are transported in such a way that the air cushion is directed into the waste line and the measuring sample and the reagents are then introduced into the measuring chamber without any air bubbles. In this way, measuring errors can be avoided. | 05-28-2009 |
20090168300 | High-voltage capacitor - A high-voltage capacitor is used to transmit energy and has an insulator housing, wherein at least two serially connected capacitors, which are mounted in parallel, are arranged. Said capacitors are made of, respectively, a serial connection of individual capacitors which are embodied as stackable capacitor elements. The resulting high-voltage capacitor is compact and economical. Each capacitor element comprises several individual capacitors which are maintained in an isolated manner, whereby the number corresponds to the number of serially connected capacitors, such that said serially connected capacitors are formed by one stack of capacitor elements. | 07-02-2009 |
Siegfried Birkle, Höchstadt DE
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20090168300 | High-voltage capacitor - A high-voltage capacitor is used to transmit energy and has an insulator housing, wherein at least two serially connected capacitors, which are mounted in parallel, are arranged. Said capacitors are made of, respectively, a serial connection of individual capacitors which are embodied as stackable capacitor elements. The resulting high-voltage capacitor is compact and economical. Each capacitor element comprises several individual capacitors which are maintained in an isolated manner, whereby the number corresponds to the number of serially connected capacitors, such that said serially connected capacitors are formed by one stack of capacitor elements. | 07-02-2009 |
Stéphane Birkle, Nantes FR
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20100150910 | USE OF MONOCLONAL ANTIBODIES SPECIFIC TO THE O-ACETYLATED FORM OF GD2 GANGLIOSIDE FOR TREATMENT OF CERTAIN CANCERS - The invention relates to the use of monoclonal antibodies that only recognise the O-acetylated form of the GD2 ganglioside, or fragments of said antibody, for the diagnosis and the treatment of cancers in which the cells express the O-acetylated GD2, said antibody or said fragment recognising the O-acetylated GD2 molecules expressed by the tumoral cells and not recognising the GD2 molecules expressed at the surface of the peripheral nerves, in order to increase the specificity of the diagnosis and reduce the toxicity of the treatments. The invention also relates to artificially modified antibodies advantageously used for treating and diagnosing cancers in which the cells express the O-acetylated GD2. | 06-17-2010 |
20140044721 | ANTI-GB3 ANTIBODIES USEFUL IN TREATING DISORDERS ASSOCIATED WITH ANGIOGENESIS - The present invention lies in the field of new cancer therapies, more precisely in the field of antiangiogenic compounds. It notably concerns anti-Gb3 antibodies having specific CDR sequences, as well as the use of anti-Gb3 antibodies not coupled to a therapeutic molecule in the treatment of diseases associated with angiogenesis, such as solid tumors. | 02-13-2014 |
Stéphane Birkle, Nantes FR
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20100150910 | USE OF MONOCLONAL ANTIBODIES SPECIFIC TO THE O-ACETYLATED FORM OF GD2 GANGLIOSIDE FOR TREATMENT OF CERTAIN CANCERS - The invention relates to the use of monoclonal antibodies that only recognise the O-acetylated form of the GD2 ganglioside, or fragments of said antibody, for the diagnosis and the treatment of cancers in which the cells express the O-acetylated GD2, said antibody or said fragment recognising the O-acetylated GD2 molecules expressed by the tumoral cells and not recognising the GD2 molecules expressed at the surface of the peripheral nerves, in order to increase the specificity of the diagnosis and reduce the toxicity of the treatments. The invention also relates to artificially modified antibodies advantageously used for treating and diagnosing cancers in which the cells express the O-acetylated GD2. | 06-17-2010 |
Thomas Birkle, Boulder, CO US
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20100002889 | SYSTEM AND METHOD FOR DESIGNING SOUND SYSTEMS - The invention is directed to a display and method for conducting sound system design. The display is configured to simultaneously show a sound system model comprising both audio components and sound environment components, a plurality of parameters and a graphic representation of a calculated sound system performance attribute. In response to receiving input from the user and without any additional user intervention, the display re-displays a newly-calculated sound system performance attribute such as, for example, a graphic representation in the sound system model of a sound path associated with a user-selected reflected sound identifier. A processor also simulates, based on the sound system configuration, the sound performance that a user would expect to hear positioned in an identified listening position of the sound system model. | 01-07-2010 |