Bettina
Bettina Aboab, Clermont-Ferrand FR
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20110263669 | Novel Pyrrolo [2,3-A] Carbazoles and Use Thereof as PIM Kinase Inhibitors - The invention relates to pyrrolo[2,3-a]carbazole derivatives, to a method for preparing the same, and to the use thereof as PIM kinase inhibitors. The invention can particularly be used in the pharmaceutical field. | 10-27-2011 |
Bettina Bardl, Jena DE
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20090142809 | Method for Cleaving Cervimycin Monoesters - The invention relates to a method for cleaving cervimycin esters. An object of the invention to convert in a simple manner the cervimycin esters which are less active but formed in larger quantity into the highly active cervimycin K that occurs as a minor component in the preparation by fermentation, is achieved by preparing unesterified cervimycins from cervimycin esters with di- or monomethylated malonic acids, by ester cleavage effected by at least one esterolytic enzyme at temperatures of 20° C. to 75° C. and a pH of pH 5.0 to 10.0, preferably pH 6.0 to 9.0. | 06-04-2009 |
Bettina Becker, Monheim DE
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20120175817 | HYDROLYTICALLY STABLE POLYAMIDE - The invention relates to the use of polyamides on the basis of reaction products from at least one dimeric fatty acid, at least one aliphatic dicarboxylic acid having 6 to 24 C atoms and aliphatic, cycloaliphatic and/or polyether diamines, wherein the quantities of amine components are selected so that primarily terminal amine groups are contained therein, and the polyamide comprises an amine count from 2 to 20 mg KOH/g to produce molded parts in the low pressure injection molding method. | 07-12-2012 |
Bettina Beyreuther, Dusseldorf DE
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20080280835 | Novel Use of Peptide Compounds For Treating Muscle Pain - The present invention is directed to the use of a class of peptide compounds for treating non-inflammatory musculoskeletal pain or/and non-inflammatory osteoarthritic pain. | 11-13-2008 |
20090241205 | METHOD FOR IDENTIFYING CRMP MODULATORS - The present invention refers to a method for identifying a modulator of CRMP suitable for the prevention, alleviation or/and treatment of CRMP-associated diseases. | 09-24-2009 |
20100029543 | METHODS FOR TREATING NUCLEOSIDE-INDUCED PAIN - The present invention is directed to the use of a class of peptide compounds for treating tumor pain, in particular bone cancer pain, for treating chemotherapy-induced pain and for treating nucleoside-induced pain. | 02-04-2010 |
20100324144 | THERAPY FOR HYPEREXCITABILITY DISORDERS - The present invention is directed to the use of a class of peptide compounds for treating diseases associated with hyperexcitability. The present invention is also directed to the use of a class of peptide compounds for treating diseases associated with dysfunction of an ion channel. | 12-23-2010 |
20110104281 | METHOD FOR TREATING PAIN USING A SUBSTITUTED 2-AMINOTETRALIN COMPOUND - A method for treating pain, particularly non-inflammatory musculoskeletal pain such as myofascial pain or back pain, in a subject comprises administering to the subject a substituted 2-aminotetralin compound as defined herein, illustratively rotigotine. | 05-05-2011 |
20120225119 | THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS - An embodiment of the present invention relates to a therapeutic combination including (a) lacosamide and/or a pharmaceutically acceptable salt thereof; and (b) levetiracetam and/or a pharmaceutically acceptable salt thereof. The combination can be provided in a single dosage form or separate dosage forms. | 09-06-2012 |
20140066515 | METHODS FOR TREATING CHANNELOPATHIES - The present invention is directed to the use of a class of peptide compounds for treating diseases associated with hyperexcitability. The present invention is also directed to the use of a class of peptide compounds for treating diseases associated with dysfunction of an ion channel. | 03-06-2014 |
Bettina Beyreuther, Duesselfdorf DE
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20090111838 | 6-ARYLAMINO-5-CYANO-4-PYRIMIDINONES AS PDE9A INHIBITORS - The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I) | 04-30-2009 |
Bettina Beyreuther, Düsseldorf DE
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20090241205 | METHOD FOR IDENTIFYING CRMP MODULATORS - The present invention refers to a method for identifying a modulator of CRMP suitable for the prevention, alleviation or/and treatment of CRMP-associated diseases. | 09-24-2009 |
Bettina Boehlendorf, Rheinfelden DE
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20130302504 | DIHYDROCHALCONE PURIFICATION PROCESS - The present invention relates to an improved process for the preparation of an extract enriched in dihydrochalcones, and more specifically enriched in phlorizin, starting from a polyphenolic fraction originating from industrial apple processing. The invention also relates to a dihydrochal-cone extract obtainable by this process, and to a food or a nutraceutical product comprising a dihydrochalcone extract of the present invention. | 11-14-2013 |
Bettina Bommarius, Atlanta, GA US
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20100048480 | PRODUCTION OF ANTI-MICROBIAL PEPTIDES - The present application provides methods of producing antimicrobial peptides (AMPs) in a cell, for example by expression a fusion protein that includes small ubiquitin related modifier (SUMO) and an AMP in the cell. Also provided are nucleic acid and protein sequences of SUMO-AMP fusion proteins, and kits that include such molecules. | 02-25-2010 |
20120003688 | COMPOSITIONS AND METHODS FOR USING NADH OXIDASES - The present disclosure relates generally to bacterial NADH oxidases and, more particularly, to novel NADH oxidases obtained from | 01-05-2012 |
20130309734 | Engineered Amine Dehydrogenases and Methods of Use Thereof - Non-naturally occurring amine dehydrogenases (AmDH) and methods of use thereof the produce chiral amines are disclosed. The AmDH are variants of amino acid dehydrogenases. AmDH based on phenylalanine, leucine, and valine scaffolds are provided. The AmDH typically have one, two, three, four, or more amino acid alterations relative to the scaffold. The alterations to the scaffold result in an enzyme that accepts the analogous ketone, such as methyl isobutyl ketone (MIBK), instead of the wild-type α-keto acid. Chimeric AmDH are also disclosed. The chimeras are fusion proteins that include a substrate binding domain from a first AmDH and a cofactor binding domain from a second AmDH. In a preferred embodiment, one of the domains is from a PheDH-based AmDH and one of the domains is from a LeuDH-based AmDH. | 11-21-2013 |
Bettina Bressel, Marl DE
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20140005344 | HARDENER FOR EPOXY RESIN SYSTEMS AND USE THEREOF | 01-02-2014 |
20140288337 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS - A process for inhibiting the polymerization of cyclopentadiene compounds (B) by contacting the cyclopentadiene compound with a quinone methide compound (A) of structure (I), | 09-25-2014 |
Bettina Darveaux, Hillsborough, NC US
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20090070897 | Genes and uses for plant improvement - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 03-12-2009 |
20140304848 | Genes and uses for plant improvement - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 10-09-2014 |
20150135367 | Genes and uses for plant improvement - Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Exemplary recombinant DNA expresses a succinate semialdehyde dehydrogenase. | 05-14-2015 |
Bettina Darveaux, Hillborough, NC US
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20100017904 | Genes and uses for plant improvement - Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein. | 01-21-2010 |
Bettina Duemmler, Kusnacht CH
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20110265194 | THEM5-MODIFIED MODELS OF NON-ALCOHOLIC FATTY LIVER DISEASE - The invention provides a new reproducible genetically-modified mouse model for the study of non-alcoholic fatty liver disease. In particular, the invention concerns the study of non-alcoholic fatty liver disease in an THEM5 knockout mouse model and its use in drug discovery and research. | 10-27-2011 |
Bettina Experton, Del Mar, CA US
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20100269157 | System and Method for User Control of Authorizing and Tracking Access to Electronic Records - A record holder accesses a coordinating server via a network. The coordinating server either itself stores or communicates electronically with one or more other servers that store electronic records (ER), including at least some associated with the record holder. Third-party record recipients are also connected via the network to the coordinating server and possibly also to the ER server(s). The user accesses the coordinating server, selects at least one of the recipients and specifies which of the electronic records, or portions thereof, that the user wishes that particular recipient to be able to access, possibly along with other access right parameters such as an access time or period. The recipient then accesses the coordinating server and/or one of the ER servers to retrieve electronic records of interest, which are made available according to the access rights and limitations pre-set by the user. | 10-21-2010 |
20120232929 | MOBILE DEVICE-BASED SYSTEM FOR AUTOMATED, REAL TIME HEALTH RECORD EXCHANGE - A method, an apparatus, and a computer program product for accessing electronic medical records are provided in which a portable computing device uniquely associated with a user authenticates an identification of the user and automatically retrieves information corresponding to the user from electronic healthcare records systems using the identification. The retrieved information may be combined with other information and electronically delivered to a healthcare provider. | 09-13-2012 |
20140207686 | SECURE REAL-TIME HEALTH RECORD EXCHANGE - A method, an apparatus, and a computer program product for accessing electronic medical records are provided in which a portable computing device uniquely associated with a user authenticates an identification of the user and automatically retrieves information corresponding to the user from electronic healthcare records systems using the identification. The retrieved information may be combined with other information and electronically delivered to a healthcare provider or patient. Delivery may be initiated by the portable computing device and directed to a computing device of a healthcare provider or patient. Exchange of records and other information between the user and the provider is effected using a first channel to provide a network address of the records and cryptographic keys necessary to extract the records, and a second path to deliver the encrypted records. The first path may be implemented using a camera or optical scanner to read an encoded optical image. | 07-24-2014 |
Bettina Fuessel, Malsch DE
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20100151588 | MEANS AND METHODS FOR DIAGNOSING AND TREATING CANCER BASED ON THE FRMD3 GENE - The present invention relates to pharmaceutical compositions comprising a FRMD3 polynucleotide or polypeptide as well as diagnostic compositions, devices or kits comprising a FRMD3 polynucleotide or polypeptide as well as antibodies or oligonucleotides derived therefrom. Moreover, the present invention relates to methods and uses for diagnosing or treating a hyperproliferative disorder based on the aforementioned FRMD3 polynucleotides or polypeptides. | 06-17-2010 |
Bettina Gajetzki, Langenfeld DE
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20140234632 | WOOD SUBSTRATE FURNISHED WITH A FLAME RETARDANT - The invention relates to a wood substrate rendered flame-retardant. The invention provides that on the substrate there is a coating and/or impregnation system with a flame retardant selected from the group consisting of room-temperature-liquid organic halogen compounds and organic phosphorus compounds and organic boron compounds, and that there is also a layer of coating material applied thereto. | 08-21-2014 |
Bettina Groschel, San Diego, CA US
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20140342362 | COMPOSITIONS, KITS, AND RELATED METHODS FOR DETECTING AND/OR MONITORING SHIGA TOXIN PRODUCING ESCHERICHIA COLI - ECF, such as the ecf operon/gene cluster (e.g., ECF2-1- and ECF2-2 described herein) may be used to detect virulent STECs including virulent non-0157:H7 STEC and virulent non-0157:H7 EHEC. Use of this nucleic acid target, in combination with other targets, such as Z5866, rfb | 11-20-2014 |
20150086982 | COMPOSITIONS AND METHODS FOR DETECTING AND DISCRIMINATING BETWEEN YEAST OR MOLD - The invention features compositions, methods, and kits for detecting and distinguishing between yeast or mold in a sample suspected of being contaminated with yeast or mold. | 03-26-2015 |
Bettina Hahn, Edingen DE
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20120003680 | ASSEMBLY OF ABSOLUTELY QUANTIFIED PEPTIDE AND PHOSPHOPEPTIDE SOLUTIONS VIA ELEMENT MASS SPECTROMETRY - The present invention relates generally to the fields of analytics of proteins and peptides. More particularly, the invention concerns generation of an absolutely quantified reference peptide or protein solution via element mass spectrometry. Furthermore, the invention relates to the absolute quantification of phosphopeptides and peptides by the use of an absolutely quantified peptide solution. | 01-05-2012 |
Bettina Hailand, Herrsching A Ammersee DE
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20110077361 | INITIATOR SYSTEM CONTAINING A DIARYLALKYLAMINE DERIVATE, HARDENABLE COMPOSITION AND USE THEREOF - The invention relates to an initiator system comprising a diarylalkylamine compound and a sensitizing agent. The invention also relates to a hardenable composition comprising the initiator system. The invention further relates to the use of the initiator system for initiating the hardening process of a hardenable composition being selected from cationically curing composition(s) and/or radically curing composition(s) or a mixture thereof. The initiator system and the hardening composition can be used in various fields, including the dental and orthodontic area. | 03-31-2011 |
20110124764 | INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF - The invention relates to an initiator system comprising (a) an iodonium salt, (b) a light sensitizer and (c) an electron donor compound comprising a biphenylene structure, the biphenylene structure comprising at least one but not more than about 4 alkyl groups. The invention also relates to a hardenable composition comprising such an initiator system and the use thereof, as well as to a process for producing the substituted biphenylene compound. | 05-26-2011 |
20130109777 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 05-02-2013 |
20130303655 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF - The invention relates to a dental composition having | 11-14-2013 |
Bettina Heblich, Heidesheim DE
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20110319402 | AEROSOL FORMULATION FOR THE INHALATION OF BETA AGONISTS - The present invention relates to a propellant-free aerosol formulation which [contains] one or more compounds of general formula (1) wherein the groups R | 12-29-2011 |
Bettina Heil, Graz AT
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20120237489 | SUPPOSITORY FOR RECTAL, VAGINAL OR URETHRAL ADMINISTRATION CONTAINING A PROBIOTIC, AN ANTIBIOTIC AND AN UNSATURATED NON-ESTERIFIED FATTY ACID - A suppository is provided for rectal, vaginal or urethral administration. A method also is provided for the preparation of a suppository for rectal, vaginal or urethral administration. The method uses at least one unsaturated, non-esterified fatty acid in a composition containing a probiotic and an antibiotic. | 09-20-2012 |
Bettina Hoffmann, Altenkunstadt DE
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20110106248 | SOFT-TISSUE IMPLANT HAVING ANTIBACTERIAL EFFECT - The invention relates to a soft-tissue implant for use in the medical field which has an antibacterial effect. The soft-tissue implant, which may for example be a breast implant, has at least one antibiotic substance bound to the implant surface in first and second configurations that release the antibiotic substance, after implanting in an animal body, at short term and long term release rates. The first and second configurations are each present at one or more common surface locations. The soft-tissue implant has an antibacterial effect that prevents or reduces the deposition of bacteria and the formation of bacteria-containing biofilms. | 05-05-2011 |
Bettina Hoffmann, Bayreuth DE
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20090263436 | Material primarily for medical, long-term in vivo use, and method for the production thereof - The invention relates to a material that is used primarily for medical, long-term in vivo purposes, e.g. as a filling material in dentistry. The aim of the invention is to create a material primarily for medical, long-term in vivo use which does not have the disadvantages of materials used in prior art, does not release active substances, and endures after the material has been removed or when the shape thereof is modified. The aim is achieved by the fact that the material is made of polymers and filling agents which are embodied as polymer-coated, chemically modified particles that carry hydroxyl groups and are surrounded by a matrix of another polymer. The coating polymer develops an antimicrobial effect. | 10-22-2009 |
Bettina Huber, Regensburg DE
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20100071475 | DEVICE FOR MONITORING THE FLOW OF WATER VAPOR - Reliably and quickly acting device that can be cheaply employed for monitoring the flow of water vapor, having a water vapor line extending between a switching valve and a cross-section connection, in particular a nozzle, and a temperature sensor monitoring the temperature in the line. | 03-25-2010 |
Bettina Husen, Hannover DE
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20080249075 | C11 Modified Retrosteroids as Progesterone Receptor Modulator Compounds - Retrosteroidal compounds corresponding to formula I, representing progesterone receptor modulators, and their production, and pharmaceutical preparations containing these compounds. These compounds are useful in the treatment of benign gynecological disorders such as endometriosis and uterine fibroids, as well as for female birth control and for hormone replacement therapy. | 10-09-2008 |
20080255075 | SUBSTITUTED ESTRATRIENE DERIVATIVES AS 17BETA HSD INHIBITORS - Substituted estratriene compounds of formula (I) useful in therapy, especially in the treatment or inhibition of a steroid hormone dependent disorder requiring the inhibition of a 17β-hydroxysteroid dehydrogenase (17β-HSD) type 1, type 2 and/or type 3 enzyme, as well as their salts, pharmaceutical compositions containing such compounds and processes for preparing such compounds. | 10-16-2008 |
20110021480 | 17-beta HSD1 and STS Inhibitors - Substituted steroid compounds which represent selective inhibitors of 17β-hydroxysteroid dehydrogenase type I (17β-HSD1) and, in addition, which may represent inhibitors of the steroid sulfatase, salts thereof, pharmaceutical preparations containing these compounds, and a process for the preparation of these compounds. Also disclosed is a therapeutic method of using such substituted steroid compounds, particularly in the treatment, inhibition, prophylaxis or prevention of steroid hormone dependent diseases or disorders, such as steroid hormone dependent diseases or disorders requiring the inhibition of 17β-hydroxysteroid dehydrogenase type I and/or steroid sulfatase enzymes and/or requiring lowering of the endogenous 17β-estradiol concentration. | 01-27-2011 |
Bettina Jackwerth, Langenfeld DE
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20100183536 | Hydrocarbon Mixture and Use Thereof - The invention relates to hydrocarbon mixtures containing linear C11 and linear C13 hydrocarbons, wherein the sum of the linear C11 and linear C13 hydrocarbons is greater than or equal to 60 wt. % with relation to the sum of the hydrocarbons, and to the use of said mixtures in cosmetic and/or pharmaceutical preparations. | 07-22-2010 |
20100189673 | Hydrocarbon Mixtures and Use Thereof - The invention relates to hydrocarbon mixtures containing the | 07-29-2010 |
20110059032 | Hydrocarbon Mixtures and use Thereof - The invention relates to a hydrocarbon mixture that contains at least two hydrocarbons that are different from each other, the number of carbons thereof differing by more than one, wherein said two hydrocarbons that differ from each other make up at least 60% by weight, preferably at least 70% by weight of the total of the hydrocarbons. The invention also relates to the use of said hydrocarbon mixtures and to cosmetic and/or pharmaceutical preparations containing said hydrocarbon mixtures. | 03-10-2011 |
20110243863 | Cosmetic And/Or Pharmaceutical Formulations - The invention relates to cosmetic and/or pharmaceutical formulations, comprising n-octyl-n-octanoate. | 10-06-2011 |
Bettina Kroeger-Kallies, Bremen DE
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20100209618 | METHOD FOR PLASMA TREATMENT AND PAINTING OF A SURFACE - A method for plasma treatment and painting of a surface, the surface including a plurality of different materials includes blasting the surface with a carbon dioxide snow so as to activate the surface to improve an adhesive strength; and treating the surface with a plasma treatment using at least one plasma nozzle following the blasting step, the treating including guiding the at least one plasma nozzle at a distance of not more than 15 mm from the surface at a feed rate of not more than 50 m/min. | 08-19-2010 |
Bettina Laugwitz, Ludwigshafen DE
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20110145737 | INTELLIGENT ROADMAP NAVIGATION IN A GRAPHICAL USER INTERFACE - Systems and methods for intelligent information navigation in a graphical user interface (GUI) where a sequence of items is generated and stored in a memory of a computer system. A number of graphical elements are displayed on a screen of a GUI, wherein each graphical element corresponds to an item of the sequence of items, and wherein the graphical elements are ordered according to the sequence. When requested, the graphical elements scroll in a chosen direction to gradually include a new graphical element into the screen at the direction of scrolling. Respectively, the scrolling could gradually exclude from the screen a graphical element at opposite direction. An item of the sequence of items could be selected as a currently active item. The displayed graphical elements are automatically scrolled to move the graphical element corresponding to the currently active item at a focal position within the screen. | 06-16-2011 |
20110145738 | NESTED ROADMAP NAVIGATION IN A GRAPHICAL USER INTERFACE - Systems and methods for nested roadmap information navigation in a graphical user interface (GUI) where a sequence of items is generated and stored in a memory of a computer system. The sequence of items includes at least one compound item. A number of user interface (UI) elements are displayed in a GUI screen, wherein each UI element represents an item of the sequence of items, and wherein the UI elements are ordered according to the sequence of items. The displayed UI elements include a UI element representing a compound item of the sequence of items. The compound item could be selected as a currently active item. The UI element representing the selected compound item can gradually expand to display one or more new UI elements representing component items subordinate to the compound item. The first of the component items is automatically selected as a currently active item. | 06-16-2011 |
Bettina Lindblom, Helsinki FI
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20100308088 | ARRANGEMENT FOR ADJUSTING THE WIDTH OF THE CARRIER MEANS - This invention relates to an arrangement for adjusting the width of a carrier ( | 12-09-2010 |
20150069097 | ARRANGEMENT FOR ADJUSTING THE LENGTH OF A CARRYING SECTION OF A CHILD CARRIER - The invention relates to an arrangement for adjusting the length of a carrying section of a child carrier, intended for carrying a child on an adult's front, back, or hip, the carrier comprising further upper support elements attached to the carrying section and to be placed over the wearer's shoulders, and lower support elements to be placed around the wearer's body, wherein the carrier is equipped with adjustment elements, with which a multi-stepped or stepless length adjustment of the carrying section is arranged to be carried out. | 03-12-2015 |
Bettina Lindbloom, Helsinki FI
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20100308087 | ARRANGEMENT FOR ADJUSTING THE HEIGHT OF A CARRIER MEANS - This invention relates to an arrangement for adjusting the height of a carrier ( | 12-09-2010 |
Bettina Löschner, Dreieich-Sprendlingen DE
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20090317790 | Method for the Production of Frozen Blood or Frozen Blood Cells for Biological Assays - The present invention relates to an improved method for cryo-preservation of human whole blood containing monocytes and lymphocytes at temperatures of between −40° C. and −60° C., preferably at −60° C., whereby the function of monocytes and lymphocytes is preserved. The present invention, particularly relates to a method for cryo-preservation of human whole blood containing monocytes and lymphocytes without the need for an isolation of peripheral blood mononuclear cells (PBMCs), or blood cells. | 12-24-2009 |
Bettina Löschner, Dreieich-Sprendlingen DE
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20090317790 | Method for the Production of Frozen Blood or Frozen Blood Cells for Biological Assays - The present invention relates to an improved method for cryo-preservation of human whole blood containing monocytes and lymphocytes at temperatures of between −40° C. and −60° C., preferably at −60° C., whereby the function of monocytes and lymphocytes is preserved. The present invention, particularly relates to a method for cryo-preservation of human whole blood containing monocytes and lymphocytes without the need for an isolation of peripheral blood mononuclear cells (PBMCs), or blood cells. | 12-24-2009 |
Bettina Malnic, Sao Paulo BR
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20080305547 | Method for enhanced functional expression of cell receptors - The invention relates to methods for enhancing functional expression of receptor molecules in recombinant cells, preferably heterologous cells. In the method, a eukaryotic cell is transformed or transfected with all of the nucleic acid molecule which encodes the receptor, one which encodes a GEF, such as Ric-8A or Ric-8B, and one which encodes Gαolf. The resulting, recombinant cells are then contacted with an agent that stimulates the functional expression of the receptor. Preferably, the receptor is an odorant receptor, or “OR,” and the agent is a ligand for that OR. | 12-11-2008 |
Bettina Meissburger, Eppelheim DE
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20140343023 | ROR GAMMA MODULATORS - The present invention relates to compounds of formula I, or a pharmaceutically acceptable salt thereof, | 11-20-2014 |
Bettina Nechay, Laurel, MD US
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20150236186 | NANO AVALANCHE PHOTODIODE ARCHITECTURE FOR PHOTON DETECTION - An integrated circuit includes a substrate material that includes an epitaxial layer, wherein the substrate material and the epitaxial layer form a first semiconductor material with the epitaxial layer having a first conductivity type. At least one nanowire comprising a second semiconductor material having a second conductivity type doped differently than the first conductivity type of the first semiconductor material forms a junction crossing region with the first semiconductor material. The nanowire and the first semiconductor material form an avalanche photodiode (APD) in the junction crossing region to enable single photon detection. In an alternative configuration, the APD is formed as a p-i-n crossing region where n represents an n-type material, i represents an intrinsic layer, and p represents a p-type material. | 08-20-2015 |
Bettina Paikert, Oberrohrdorf CH
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20090277182 | FUEL LANCE - A lance is presented for introducing fuel into a second burner of a combustion chamber of a gas turbine installation with sequential combustion, having a first and a second combustion chamber. The lance includes a foot and a shank which projects from it. In an installed state of the lance the foot extends perpendicularly or at an angle to a main flow direction of the burner. The shank extends centrally in the burner and generally parallel to the main flow direction. At least one projecting arm, having at least one nozzle for introducing fuel, is arranged such that it extends from the shank. A respective end of the at least one arm is oriented in the main flow direction and extends generally parallel to the main flow direction. | 11-12-2009 |
20110059408 | METHOD AND BURNER ARRANGEMENT FOR THE PRODUCTION OF HOT GAS, AND USE OF SAID METHOD - A method for producing hot gas for operating a turbomachine fired with at least one combustion chamber includes premixing a fuel with a plurality of operating gases by introducing fuel into the plurality of operating gases in a mixing chamber disposed upstream of the combustion chamber using a burner arrangement, wherein the fuel includes at least one of a combustible gas and a H | 03-10-2011 |
20130224672 | METHOD AND BURNER ARRANGEMENT FOR THE PRODUCTION OF HOT GAS, AND USE OF SAID METHOD - A method for producing hot gas for operating a turbomachine fired with at least one combustion chamber includes premixing a fuel with a plurality of operating gases by introducing fuel into the plurality of operating gases in a mixing chamber disposed upstream of the combustion chamber using a burner arrangement, wherein the fuel includes at least one of a combustible gas and a H | 08-29-2013 |
20140065562 | PREMIX BURNER - This invention relates to a premix burner for operating a heat generator, the burner at least having a swirl generator, a mixing section downstream of the swirl generator and a transition piece for transferring the swirl flow from the swirl generator into the mixing section. The invention further refers to a transition piece for such a premix burner. The transition piece includes an inlet, connected to the swirl generator, an outlet, connected to the mixing tube, and a continuing flow limiting interior contour between said inlet and said outlet, wherein at least in an inlet section said interior contour is curved radially inwards towards the inner diameter of the mixing tube and wherein at the outlet the interior contour is flush with an interior flow limiting contour of the mixing tube. | 03-06-2014 |
20140109583 | BURNER - The burner includes a swirl chamber. The swirl chamber has a substantially conical shape defining a central axis. The swirl chamber is defined by a plurality of wall elements. A combination of nozzles at the pressure, suction side and trailing edge of the wall element are placed for fuel injection. The wall elements define slots between each other. The slots have different widths (w) in consecutive planes in the axial direction, wherein said planes are perpendicular to the central axis. | 04-24-2014 |
Bettina Rebaud, Gilly Sur Isere FR
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20120074982 | DEVICE FOR MONITORING THE OPERATION OF A DIGITAL CIRCUIT - A digital electronic circuit includes: a plurality of sequential elements; at least one data-conducting path connecting an input sequential element to a destination sequential element; a clock outputting a clock signal on a clock tree for setting the speed of the sequential elements; a monitoring device receiving, as an input, at least one data signal traveling on a conducting path and arriving at a destination sequential element, the monitoring device including: a module for defining at least one detection window according to the clock tree; and a detector for detecting a transition of each data signal received during a detection window; and wherein each detection window is defined so as to enable the detection or anticipation of a fault corresponding to a violation of the rise time or the maintenance time of a data signal relative to a clock signal edge received by the destination sequential element receiving the data signal. | 03-29-2012 |
Bettina Rebaud, Grenoble FR
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20110029795 | DEVICE FOR POWERING AN ELECTRONIC CIRCUIT, IN PARTICULAR A DIGITAL CIRCUIT, AND ASSOCIATED METHOD - A device for powering an electronic circuit that applies at least a first voltage or a second voltage, different from the first voltage, to the electronic circuit. The device includes a performance monitor that receives an item of information defining a constraint and determines a first duration and a second duration, such that the operation of the electronic circuit at a first frequency associated with the first voltage for the first duration, and at a second frequency associated with the second voltage for the second duration, complies with the constraint. The device applies the first voltage and the first frequency to the circuit for the first duration and the second voltage and the second frequency for the second duration. | 02-03-2011 |
Bettina Rosche, Randwick AU
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20080280337 | Process for the Production of Citronellal - The invention relates to a process for the production of optically active Citronellal by enzymatic reduction of Citral with a reductase from | 11-13-2008 |
20100009421 | Method For The Enzymatic Reduction Of Alkyne Derivates - The invention relates to a method for the enzymatic reduction of alkyne derivatives of the formula (1), | 01-14-2010 |
Bettina Rudoplh, Hannover DE
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20090170095 | Mnk KINASE HOMOLOGOUS PROTEINS INVOLVED IN THE REGULATION OF ENERGY HOMEOSTASIS AND ORGANELLE METABOLISM - The present invention discloses Mnk homologous proteins regulating the energy homeostasis, the metabolism of triglycerides, and/or is contributing to membrane stability and/or function of organelles, and polynucleotides, which identify and encode the proteins disclosed in this invention. The invention also relates to the use of these sequences in the diagnosis, study, prevention, and treatment of diseases and disorders related to body-weight regulation and thermogenesis, for example, but not limited to, metabolic diseases such as obesity, as well as related disorders such as eating disorder, cachexia, diabetes mellitus, hypertension, coronary heart disease, hypercholesterolemia, dyslipidemia, osteoarthritis, gallstones, and sleep apnea, and disorders related to ROS defence, such as diabetes mellitus, neurodegenerative disorders, and cancer, e.g. cancers of the reproductive organs, and others. | 07-02-2009 |
Bettina Sarg, Axems AT
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20120190561 | MEANS AND METHODS FOR DIAGNOSING ENDOMETRIOSIS - The present invention relates to means and methods for diagnosing or predicting endometriosis in a female subject. Particularly, the present invention relates to methods for determining the susceptibility to, predisposition for, presence of and/or risk of developing or suffering from endometriosis in a female subject. The present invention also relates to a kit useful for determining the risk of developing or suffering from endometriosis in a subject, a binding molecule specifically binding to the DBP GC*2 or DBP GC*1 allele product, and a binding molecule binding to the gene encoding the DBP GC*2 or GC*1 allele. | 07-26-2012 |
Bettina Schelkle, Cardiff GB
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20120276227 | USE OF CAJEPUT AND PIMENTA RACEMOSA EXTRACT FOR TREATING PARASITIC INFESTATION OF FISH - The present invention relates to a combination of cajeput and extract from the plant | 11-01-2012 |
Bettina Schwaier, Munchen DE
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20120269930 | COMPOSITION COMPRISING A LIPID SUITABLE FOR HUMAN CONSUMPTION - The present invention relates to a composition comprising at least one lipid suitable for human consumption, at least one water soluble sweetener, and at least one solubilizer, wherein water soluble sweetener means that at least 2 g sweetener are soluble in 1 l of water at a temperature of 20° C. | 10-25-2012 |
20120308710 | Drink - The present invention relates to a drink which is an oil-in-water emulsion and which comprises hydrocolloids, where the hydrocolloids are a mixture of gellan and pectin, and where the oil phase or fat phase comprises sterols or stanols or fatty acid esters of sterols or fatty acid esters of stanols or a mixture of these substances. The hydrocolloids prevent or retard the settling of a precipitate of the oil phase or fat phase of the oil-in-water emulsion. | 12-06-2012 |
20120308711 | Drink - The present invention relates to a drink which is an oil-in-water emulsion and which comprises hydrocolloids, where the hydrocolloids are a mixture of gellan and pectin. The hydrocolloids prevent or retard the creaming of the oil phase or fat phase of the oil-in-water emulsion. | 12-06-2012 |
Bettina Strack-Logue, Somerville, MA US
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20110318327 | TREATMENT OF SANFILIPPO SYNDROME TYPE B - Among other things, the present invention provides methods and compositions of treating Sanfilippo syndrome type B (Sanfilippo B) by, e.g., intrathecal (IT) administration of a Naglu protein. A suitable Naglu protein can be a recombinant, gene-activated or natural protein. In some embodiments, a suitable Naglu protein is a recombinant Naglu protein. In some embodiments, a recombinant Naglu protein is a fusion protein containing a Naglu domain and a lysosomal targeting moiety. In some embodiments, the lysosomal targeting domain is an IGF-II moiety. | 12-29-2011 |
20130195836 | MANNOSE RECEPTOR C TYPE 1 (MRC1) CODON OPTIMIZED CELL LINE AND USES THEREOF - Described herein are isolated nucleic acid molecules comprising nucleotide sequence encoding mannose receptor, C type 1 (MRC1) wherein the 5′ region of the nucleotide sequence encoding MRC1 is codon optimized; cells comprising such nucleic acid molecules; and methods of detecting antibody production, e.g., neutralizing antibody production, in a subject being treated for Gaucher disease using such cells. | 08-01-2013 |
20130295077 | TREATMENT OF SANFILIPPO SYNDROME TYPE B - Among other things, the present invention provides methods and compositions of treating Sanfilippo syndrome type B (Sanfilippo B) by, e.g., intrathecal (IT) administration of a Naglu protein. A suitable Naglu protein can be a recombinant, gene-activated or natural protein. In some embodiments, a suitable Naglu protein is a recombinant Naglu protein. In some embodiments, a recombinant Naglu protein is a fusion protein containing a Naglu domain and a lysosomal targeting moiety. In some embodiments, the lysosomal targeting domain is an IGF-II moiety. | 11-07-2013 |
20140135275 | MITOCHONDRIAL TARGETING AND THERAPEUTIC USE THEREOF - The present invention provides, among other things, compositions and methods for treatment of Friedrich's Ataxia based on effective targeting of a therapeutic moiety to mitochondria that can substitute for natural FXN protein activity or rescue one or more phenotypes or symptoms associated with frataxin-deficiency. In some embodiments, the present invention provides a targeted therapeutic comprising a therapeutic moiety, which is a polypeptide having an N-terminus and a C-terminus, a mitochondrial targeting sequence associated with the therapeutic moiety at the N-terminus, and a mitochondrial membrane-penetrating peptide associated with the therapeutic moiety at the C-terminus, wherein the therapeutic moiety is targeted to mitochondria upon cellular entry. | 05-15-2014 |
Bettina Straub-Jubb, Weiterstadt DE
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20100187294 | CARTON PACKAGING WITH FILM INTERNAL CONTAINER, PREFABRICATED CARTON UNIT FOR THE PRODUCTION THEREOF, AND PROCESS FOR THE PRODUCTION OF CARTON PACKAGING OF THIS TYPE - In carton packaging having an outer folding carton and an inner folding carton which surrounds a film internal container, the inner folding carton is adhesively bonded by means of one of its carton body walls ( | 07-29-2010 |
Bettina Tschiersch, Quedlinburg DE
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20120156718 | Production of Ketocarotenoids in Plants - The present invention relates to optimized ketolase coding sequences, corresponding coding sequences and genetic constructs alone or in combination with beta-cyclase coding sequences, their use for the expression in plants, in particular in plants of the genus | 06-21-2012 |
Bettina Tschiersch, Sachsen-Anhalt DE
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20100064389 | Polynucleotides Encoding Truncated Sucrose Isomerase Polypeptides for Control of Parasitic Nematodes - The invention provides polynucleotides encoding N-terminal truncated forms of sucrose isomerase polypeptides which are capable of conferring increased nematode resistance in a plant. The invention also provides methods of producing transgenic plants with increased nematode resistance, seeds of such transgenic plants, and expression vectors, all of which comprise the polynucleotides of the invention. | 03-11-2010 |
Bettina Wagner, Wernberg-Koblitz DE
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20140161551 | Rotary Tool, In Particular Reaming Tool and Adjustment Element For a Rotary Tool - In order to ensure highly precise setting, in particular readjustment of the radial position of the blade in the case of a rotary tool, in particular a reamer, an adjustment element, in particular in the form of an adjustment screw, having a cone formed by the screw head is inserted into an end-side receptacle in a cutting section, said cone being provided with a friction-reducing coating. | 06-12-2014 |
Bettina Wanko, Vienna AT
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20150071951 | VACCINE - The present invention relates to a vaccine comprising at least two fragments of Proprotein convertase subtilisin/kexin type 9 (PCSK9), wherein said at least two fragments comprise at least 8 consecutive amino acid residues of amino acid residues 150 to 170 and/or 205 to 225 of PCSK9 (SEQ ID No. 9). | 03-12-2015 |
Bettina Wehren, Goch-Hassum DE
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20080314549 | MOLDING MATERIAL MIXTURE, MOLDED PART FOR FOUNDRY PURPOSES AND PROCESS OF PRODUCING A MOLDED PART - Molding material mixture, molded part for foundry purposes and process of producing a molded part. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner. | 12-25-2008 |
Bettina Werner, Huckeswagen DE
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20080234417 | Microcoating Comprising Siloxanes - The invention relates to a binding agent comprising an aqueous, film-forming, polymeric siloxane. The invention also relates to a coating agent that is produced using said binding agent and to a workpiece that is coated with said coating agent. | 09-25-2008 |
Bettina Werner, Wetter DE
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20100221568 | Silicon-Based Anticorrosive Agent - The invention relates to an anticorrosive agent comprising zinc dust, and a second component, an organic binder and a VOC-free or VOC-compatible solvent. In order to allow the metal workpieces to be coated in a reliable and energy-saving manner at constant quality, the binder comprises silicon dioxide and alkali silicate in a molar ratio of at least 4:1. The invention also relates to a device for mixing and metering solid and liquid components of an anticorrosive agent. Said device comprises means for metering the quantities of the respective components of the anticorrosive agent, a solution tank and a mixing device. An application system for applying the anticorrosive agent to a workpiece comprises a solution tank, feeding means, at least one pressure reducer connected to the solution tank and at least one spraying device connected to the solution tank. | 09-02-2010 |
Bettina Wuestenberg, Basel CH
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20110119995 | NOVEL USE OF CAROTENOID (ESTER)S - The present invention relates to a composition comprising a) a substance selected from the group of astaxanthinmonoalkanoylesters, astaxanthindialkanoylesters, isozeaxanthin, isozeaxanthinmonoalkanoylesters, isozeaxanthindialkanoylesters and mixtures thereof; and b) a substance selected from the group of alkyl nitrates, nitrooxy esters of alkoxy substituted aliphatic alcohols and organic peroxides; as well as to a change in oxidation reactions of hydrocarbons, especially fuels, admixed to these compositions. The invention also relates to a composition comprising a) a compound selected from the group consisting of astaxanthinmonoalkanoylesters, astaxanthindialkanoylesters, iso-zeaxanthin, iso-zeaxanthinmonoalkanoylesters, iso-zeaxanthindialkanoylesters and mixtures thereof; and c) a fuel. Furthermore, the present invention relates to a composition comprising a) a compound selected from the group consisting of astaxanthinmonoalkanoylesters, astaxanthindialkanoylesters, isozeaxanthin, isozeaxanthinmonoalkanoylesters, isozeaxanthindialkanoylesters and mixtures thereof; and b) a compound selected from the group of alkyl nitrates, nitrooxy esters of alkoxy substituted aliphatic alcohols, organic peroxides and mixtures thereof; and d) a stabilizing compound; and e) optionally a solvent. | 05-26-2011 |
Bettina Wuestenberg, Mohlin CH
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20120210634 | NITROOXYESTERS, THEIR PREPARATION AND USE - The present invention relates to the novel compounds of the formula (I), as well as to their manufacture and use and compositions comprising them. The invention also relates to a change in oxidation reactions of hydrocarbons admixed to these compounds. Furthermore the invention relates to (bio)diesel fuel comprising such compounds. | 08-23-2012 |
Bettina Wuestenberg, Ritterhude DE
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20100190868 | PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF - Novel photochromic and electrochromic hexadiene compounds are described. The compounds are reversibly convertible between ring-open and ring-closed isomeric forms as indicated in structures I(o) and I(c) below. (See formula in original abstract of application) The conversion between the different isomeric forms may be induced by light or electricity. In one embodiment the compounds may include a charge transfer moiety including electron donor and acceptor groups. The electron donor and acceptor are linearly conjugated in the ring-open form to enable electron transfer but are electrically insulated in the ring-closed form. Methods for synthesizing the compounds from photochemically and/or electrically inert precursors are also described. For example, the photoresponsive compounds may be synthesized by reacting diene precursors with dienophiles in a condensation reaction. The compounds may be utilized in reactivity-gated photochromic or electrochromic applications. In one embodiment of the invention, compounds of the invention may be used in a method to selectively release a releasable agent, such as a small molecule. According to this method, a photochemically inert precursor compound is reacted with the releasable agent to form a carrier compound comprising a switching moiety, the switching moiety being reversibly convertible between a thermally unstable form and a thermally stable form. The switching moiety may be selectively converted between the first and second forms to cause controlled release of the releasable agent from the carrier compound. | 07-29-2010 |
Bettina Wuestenberg, Kaiseraugst CH
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20150031910 | CATALYTIC SYNTHESIS OF VITAMIN A INTERMEDIATE - The present invention relates to a process of production of a compound, which is useful as an intermediate (building block) in organic synthesis, especially in the synthesis of vitamin A or β-carotene and derivatives thereof, e.g. canthaxanthin, astax-anthin or zeaxanthin. | 01-29-2015 |
Bettina Wüstenberg, Kaiseraugst CH
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20130211080 | PROCESS FOR THE MANUFACTURE OF TMHQ - The present invention is directed to a process for the manufacture of 2,3,5-trimethyl-hydro-p-benzoquinone comprising the following steps: a) hydrogenating 2,6-dimethyl-p-benzoquinone with hydrogen in the presence of a hydrogenation catalyst in an organic solvent to obtain 2,6-dimethyl-hydro-p-benzoquinone; b) reacting 2,6-dimethyl-hydro-p-benzoquinone with a secondary amine and formal-dehyde in an organic solvent to obtain 2,6-dimethyl-3-(N,N-disubstituted aminomethyl)-hydro-p-benzoquinone; c) reacting 2,6-dimethyl-3-(N,N-disubstituted aminomethyl)-hydro-p-benzoquinone with hydrogen in the presence of a hydrogenolysis catalyst in an organic solvent to obtain 2,3,5-trimethylhydro-p-benzoquinone; wherein the organic solvent in all steps a), b) and c) is independently selected from the group consisting of methyl tert.-butyl ether, ethyl tert.-butyl ether, tert.-amyl ether, methoxycyclopentane and any mixtures thereof. Preferably the organic solvent used in all steps a), b) and c) is the same. | 08-15-2013 |
Bettina Wüstenberg, Kaiseraugst CH
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20130211080 | PROCESS FOR THE MANUFACTURE OF TMHQ - The present invention is directed to a process for the manufacture of 2,3,5-trimethyl-hydro-p-benzoquinone comprising the following steps: a) hydrogenating 2,6-dimethyl-p-benzoquinone with hydrogen in the presence of a hydrogenation catalyst in an organic solvent to obtain 2,6-dimethyl-hydro-p-benzoquinone; b) reacting 2,6-dimethyl-hydro-p-benzoquinone with a secondary amine and formal-dehyde in an organic solvent to obtain 2,6-dimethyl-3-(N,N-disubstituted aminomethyl)-hydro-p-benzoquinone; c) reacting 2,6-dimethyl-3-(N,N-disubstituted aminomethyl)-hydro-p-benzoquinone with hydrogen in the presence of a hydrogenolysis catalyst in an organic solvent to obtain 2,3,5-trimethylhydro-p-benzoquinone; wherein the organic solvent in all steps a), b) and c) is independently selected from the group consisting of methyl tert.-butyl ether, ethyl tert.-butyl ether, tert.-amyl ether, methoxycyclopentane and any mixtures thereof. Preferably the organic solvent used in all steps a), b) and c) is the same. | 08-15-2013 |
Bettina Zedlitz, Wiesloch DE
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20110072092 | Message Mapping Management for Online Service Applications - The semantic message maintenance system provides a tool for a system with a backend and set of intermediate systems to maintain semantics of a message such that the end user can receive the information provided by the backend system in a manner that is comprehendible to the end user who has no specific knowledge of the functioning of the backend system. A message mapping system uses a series of mapping definitions and standardized identification fields. Both variable data textual data can be preserved. | 03-24-2011 |
Bettina Ziegelmann, Neuhausen DE
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20150196028 | Pheromone Composition for Treating Varroa Mite Infestation - A composition and method for treating a | 07-16-2015 |