Patent application number | Description | Published |
20080306263 | Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation - Process for the preparation of tetrahydropterin and tetrahydropterin derivatives by hydrogenating pterin and pterin derivatives with hydrogen in the presence of a hydrogenating catalyst, in which the hydrogenation is carried out in a polar reaction medium and metal complexes that are soluble in the reaction medium are employed as the hydrogenation catalysts. The process is suited to the hydrogenation, particularly asymmetric hydrogenation, of folic acid, folio acid salts, folio acid esters, folio acid ester salts or dihydroforms thereof, with the proviso that in the event of using folic acid, carboxylic acid salts thereof or dihydroforms thereof the reaction medium is aqueous, and in the event of using folic acid esters, folic acid ester salts or dihydroforms thereof the reaction medium is an alcohol. The process opens up straightforward access to achiral and chiral pterin derivatives. | 12-11-2008 |
20090082581 | Ferrocenyl ligands, production and use thereof - The invention relates to the compounds of formula (I) in the form of enantiomer-pure diastereomers or a mixture of diastereomers, wherein R′ | 03-26-2009 |
20090124812 | Ferrocenediphosphines - Compounds of the formula I in the form of enantiomerically pure diastereomers or a mixture of diastereomers, (I), where the radicals R | 05-14-2009 |
20090156851 | Ferrocene-Diphosphine Ligands - Compounds of the formula (I) in the form of racemates, mixtures of stereoisomers or optically pure stereoisomers, formula (I), where X | 06-18-2009 |
20090171114 | Chiral Ligands Used in Transition Metal Catysts for Asymmetric Addition Reactions Especially Hydrogenation - Ligands of the formula (I) secondary phosphine-Q-P(═O)HR | 07-02-2009 |
20090312566 | Multiply substituted ferrocenes - Disclosed are compounds of formulas (I) and (II) in the form of enantiomer-pure diastereomers or diastereomer mixtures. In said formulas (I) and (II), R′ | 12-17-2009 |
20100029967 | Diphosphine ligands - Compounds of the formulae I and Ia in the form of mixtures of diastereomers or pure diastereomers, (I), (Ia), where R | 02-04-2010 |
20100160660 | BIS(FERROCENYLPHOSPHINO) FERROCENE LIGANDS USED IN ASSYMETRIC HYDROGENATION REACTIONS - Abstract Compounds of the formula (I) in the form of racemates, enantiomerically pure diastereomers or a mixture of diastereomers, where the radicals R | 06-24-2010 |
20110098485 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS - Compounds of the formula I, in the form of mixtures comprising predominantly one enantiomer or in the form of pure enantiomers, secondary phosphine-Q-P*(═O)HR | 04-28-2011 |
20110251416 | CHIRAL LIGANDS - Process for preparing ligands of the formula (1), in which R | 10-13-2011 |
20130267714 | BIDENTATE CHIRAL LIGANDS FOR USE IN CATALYTIC ASYMMETRIC ADDITION REACTIONS - Compounds of the formula (I) in the form of a mixture of predominantly one diastereomer or in the form of pure diastereomers, | 10-10-2013 |