Balkwill
Anthony W. Balkwill, Berkshire GB
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20110042419 | METERED DOSE VALVE - An aerosol metering valve comprising: (a) a valve stem movable between a rest position and a firing position comprising: a body portion comprising a circumferential sealing surface (b) a valve body comprising: a body wall, and an internal chamber defined at least in part by the body wall; and (c) a metering gasket having an inner periphery defining an aperture, being disposed near the most interior end of the internal chamber and being configured to be able to form a transient, substantially fluid-tight face seal against the circumferential sealing surface of the valve stem, where at the rest position of the valve stem, the body portion of the valve stem is located within the internal chamber and as the valve stem is moved from its rest position towards its firing position the circumferential sealing surface of the valve stem contacts the metering gasket to form a face seal thereby closing a metering chamber and thereafter further movement of the valve stem towards its firing position causes the metering gasket to deflect while maintaining the seal with the circumferential sealing surface of the valve stem; and wherein the metering gasket in an unbiased configuration is an annular disc having a substantially planar form and where the valve is constructed and arranged such that the inner periphery of the metering gasket is urged out of said substantially planar form at the rest position of the valve stem, or wherein the metering gasket is pre-biased into a dished-shape. | 02-24-2011 |
Frances Balkwill, London GB
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20100278844 | Cancer Marker and Therapeutic Target - Chemokine receptor CCR4 and its ligands CCL1 7 and CCL22 are used as markers for the identification and/or staging of cancer. The level of CCR4, CCL17 and CCL22 are found to increase during malignant tumour progression. CCR4, CCL17 and CCL22 are used as markers for the stratification of cancer patients according to their suitability for treatment with anti-cancer agents. Information of diagnostic character is provided by measuring the level of one or more of CCR4, CCL 17 and CCL22 present in a patient sample. Methods of treatment of cancer patients which agents that modulate the activity of CCR4, CCL17 and CCL22. Methods of screening for agents which modulate the biological activities of CCR4, CCL 17 and CCL22 provide anti-cancer agents. | 11-04-2010 |
Matthew Balkwill, Wiltshire GB
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20100075678 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR STRESS TESTING MOBILE NETWORK EQUIPMENT USING A COMMON PUBLIC RADIO INTERFACE (CPRI) - Methods, systems, and computer readable media for stress testing mobile network equipment using CPRI are disclosed. According to one method, a plurality of messages is generated for simulating a plurality of user equipment (UE) devices. The plurality of messages is transmitted over a common public radio interface (CPRI) link to a radio equipment controller (REC) in order to stress test the REC component. | 03-25-2010 |
Matthew John Balkwill, Trowbridge GB
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20120150521 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR SIMULATING REALISTIC MOVEMENT OF USER EQUIPMENT IN A LONG TERM EVOLUTION (LTE) NETWORK - Methods, systems, and computer readable media for simulating realistic movement of user equipment in an LTE network are disclosed. According to one method, a logical topology of a long term evolution (LTE) access network is defined that includes defining connections between one or more eNodeBs (eNBs). A physical topology of the LTE access network is defined that includes defining locations of the eNBs and sectors, where the physical network topology is mapped to the logical network topology. One or more problem areas are defined within the physical network topology, where the one or more problem areas include locations where signal quality is degraded. One or more paths are defined through the physical network topology. A traffic profile for a user equipment (UE) device is defined. A plurality of messages is generated for simulating the movement of a UE device along a path through the physical network topology. | 06-14-2012 |