Bailey, PA
David Ronald Bailey, Muncy, PA US
Patent application number | Description | Published |
---|---|---|
20140075876 | MODULAR ENTRANCE FLOOR SYSTEM - A modular entrance floor system comprising a plurality of floor sections, the plurality of floor sections being disposed adjacent each other and defining a perimeter of an entrance floor area. Each floor section includes a base plate permanently coupled to a foundation, and a surface plate removably attached to the base plate. The surface plate has at least one drain feature. The plurality of floor sections are configured such that the surface plate of a first floor section is interchangeable with the surface plate of a second floor section, independent of the adjacent floor sections. | 03-20-2014 |
Derek Wayne Bailey, Conshohocken, PA US
Patent application number | Description | Published |
---|---|---|
20110162599 | COUNTERPOISE ENGINE - Methods and systems may include an engine having a crankshaft with a longitudinal axis and a plurality of pistons coupled to the crankshaft. The engine may also include a bore structure having surfaces that define a plurality of combustion chambers, wherein each combustion chamber contains a piston and the bore structure rotates about the longitudinal axis in response to piston displacement within the combustion chambers. | 07-07-2011 |
Donald Lee Bailey, Harrisburg, PA US
Eileen M. Bailey, Landenberg, PA US
Patent application number | Description | Published |
---|---|---|
20090187197 | Knit PTFE Articles and Mesh - Disclosed is a knitted article, and a method of producing such an article, having at least one PTFE fiber with oriented fibrils forming multiple fiber cross-over points wherein PTFE fiber is self-bonded in at least one of the cross-over points. | 07-23-2009 |
Gregory Bailey, State College, PA US
Patent application number | Description | Published |
---|---|---|
20130253589 | Pedicle Screw Assembly with Locking Cap - A locking pedicle screw assembly has been designed which avoids misalignment and locks into place once the cap is fully threaded into the tulip, avoiding over tightening or stripping of the threads. The locking cap includes a retaining or locking ring, positioned either at the bottom of the cap so that it locks into a groove at the bottom of the threads in the tulip or at the top of the threads in the cap, locking into a groove at the top of the tulip when the cap is fully seated. In one embodiment, an audible signal is generated when the cap locks. In another embodiment, the cap is secured to a swiveling saddle that locks the rod into place as the screw cap is tightening, but does not interfere with the locking mechanism. | 09-26-2013 |
20150148809 | DYNAMIC CORPECTOMY CALIPERS AND METHODS OF USE THEREOF - Corpectomy calipers are provided that are capable of measuring both the distance and the angle between two bodies, in particular between two vertebral bodies in an individual. The calipers provided are capable of providing reliable measurements without the need for repeated measurements. The calipers described herein offer a simple and inexpensive solution. Methods of using the calipers are provided, for example, in determining the size and spacing of a void in a corpectomy or intervertebral fusion procedure. | 05-28-2015 |
James Matthew Bailey, Stevenage, PA US
Patent application number | Description | Published |
---|---|---|
20120101083 | S1P1 AGONISTS COMPRISING A BICYCLIC N-CONTAINING RING - The present invention relates to novel compounds of formula (I) having S1P1 agonist activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders. | 04-26-2012 |
Jason Bailey, Reading, PA US
Patent application number | Description | Published |
---|---|---|
20150060346 | Hood for Preventing the Discharge of Debris from a Wastewater Collection Basin - An oil and debris separation hood mounts on the interior surface of a wastewater collection basin to cover the outlet opening and prevent hydrocarbons, debris and other pollutants from being discharged from the collection basin. The hood device includes a rounded body portion formed with a mounting flange extending along the back side of the hood device from a bottom edge and over the top portion. The upper portion of the hood device includes an access port closed by a sealable lid to provide access to the outlet pipe without removing the hood device from the collection basin. The top portion of the mounting flange is formed with a built-in vent opening that allows the pressure within the hood device to be equalized to the ambient air. The hood device can be formed from plastic sheet material through thermoforming techniques, and includes strengthening ribs and a hand grip. | 03-05-2015 |
Jessica A. Bailey, Pittsburgh, PA US
Patent application number | Description | Published |
---|---|---|
20120248394 | Corner Latching Play Yard - A foldable structure includes: an upper assembly forming an upper portion of the structure; a base assembly forming a lower portion of the structure; a centrally-located hub assembly operatively connected to the base assembly; and a post extending from each corner of the upper assembly to a corner of the base assembly. The upper assembly includes a plurality of arm assemblies. At least one latching mechanism is provided at each corner of the upper assembly extending from an upper portion of at least one of the posts to a portion of at least one of the arm assemblies. | 10-04-2012 |
20140123385 | Corner Latching Play Yard - A foldable structure includes: an upper assembly forming an upper portion of the structure; a base assembly forming a lower portion of the structure; a centrally-located hub assembly operatively connected to the base assembly; and a post extending from each corner of the upper assembly to a corner of the base assembly. The upper assembly includes a plurality of arm assemblies. At least one latching mechanism is provided at each corner of the upper assembly extending from an upper portion of at least one of the posts to a portion of at least one of the arm assemblies. | 05-08-2014 |
20140325756 | Corner Latching Play Yard - A foldable structure includes: an upper assembly forming an upper portion of the structure; a base assembly forming a lower portion of the structure; a centrally-located hub assembly operatively connected to the base assembly; and a post extending from each corner of the upper assembly to a corner of the base assembly. The upper assembly includes a plurality of arm assemblies. At least one latching mechanism is provided at each corner of the upper assembly extending from an upper portion of at least one of the posts to a portion of at least one of the arm assemblies. | 11-06-2014 |
Kevin P. Bailey, Stoneboro, PA US
Patent application number | Description | Published |
---|---|---|
20090095248 | POWER ASSEMBLY FOR INTERNAL COMBUSTION ENGINE WITH IN-CYLINDER DEPOSIT SCRAPER - A power assembly for an internal combustion engine includes a cylinder with a circular wall defining a first inside diameter. A piston is reciprocably housed within the cylinder. An integral, unitary piston deposit scraper is formed in a portion of the circular wall of the cylinder by upsetting a portion of the metallic wall so as to configure a piston scraper with a second inside diameter which is less than the first inside diameter. The inside diameter of the piston scraper closely matches that of the outside diameter of the top land of the piston. As a result, the piston scraper removes combustion deposits from the piston each time it moves into the top dead center position. | 04-16-2009 |
Kevin Paul Bailey, Grove City, PA US
Patent application number | Description | Published |
---|---|---|
20110307127 | METHOD AND SYSTEM FOR CONTROLLING ENGINE PERFORMANCE - Methods and systems are provided for operating a vehicle including an engine comprising a turbocharger including a compressor and a turbine. The engine further includes a bypass path configured to selectively route gas from downstream of the compressor to upstream of the turbine. In one embodiment, the method comprises selectively increasing gas flow to the engine by adjusting gas flow through the bypass path from downstream of the compressor to upstream of the turbine. In this manner, the performance of the engine may be adjusted for various operating conditions. | 12-15-2011 |
20130231806 | METHOD AND SYSTEM FOR CONTROLLING ENGINE PERFORMANCE - Methods and systems are provided for operating a vehicle including an engine comprising a turbocharger including a compressor and a turbine. The engine further includes a bypass path configured to selectively route gas from downstream of the compressor to upstream of the turbine. In one embodiment, the method comprises selectively increasing gas flow to the engine by adjusting gas flow through the bypass path from downstream of the compressor to upstream of the turbine. In this manner, the performance of the engine may be adjusted for various operating conditions. | 09-05-2013 |
Michael A. Bailey, Aston, PA US
Patent application number | Description | Published |
---|---|---|
20150018479 | FREE RADICAL COATING COMPOSITION WITH IMPROVED SURFACE CURE PROPERTIES - A crosslinking monomer for a peroxide cure composition is disclosed. The crosslinking monomer is a dual functional monomer and has at least two allyl groups and at least one (meth)acrylate group. A two-part peroxide composition comprises the crosslinking monomer, at least one (meth)acrylate monomer, and a peroxide initiator. | 01-15-2015 |
Michael Darrell Bailey, Philadelphia, PA US
Patent application number | Description | Published |
---|---|---|
20160058672 | Baby bottle designed for cleaning without a brush - The present invention is an improved baby bottle with at least one wide diameter aperture to allow persons who have large hands to clean the bottle without using a brush. The baby bottle is comprised of an upper body, a lower body, and a coupler. The upper body and the lower body are connected by the coupler. The exterior surface of upper body and the exterior surface of the lower body have threaded necks that surround the apertures of the upper and lower bodies respectively. The apertures of the baby bottle are of sufficient size to accommodate a human hand. The threaded necks of the upper body and threaded neck of the lower body allow the upper and lower bodies to be screwed into threads of the interior surface of the coupler. | 03-03-2016 |
Michael S. Bailey, Landenberg, PA US
Patent application number | Description | Published |
---|---|---|
20080233414 | EXTRUDED MOLTEN POLYMERIC FILM BONDING OF SOLID POLYMERIC FILM TO FLAT-ROLLED SHEET METAL CONTINUOUS STRIP - Method steps and apparatus combinations for continuous in-line polymeric coating of rigid corrosion-protected flat-rolled sheet metal continuous-strip substrate utilizing a thermoplastic polymeric material having adhesive characteristics, capable of molten thin-film extrusion for chemical-bonding with an activated-surface of the flat-rolled sheet metal substrate, and substantially-simultaneously bonding with a solid-film polymeric material; establishing multiple-polymer-layers traveling with said activated surface; said solid polymeric film being selected to provide strength, hardness and other desired surface mechanical properties; and, also, providing for external surface coloration, design, weather-proofing, and fabricating capabilities; a second embodiment provides dual-surface multiple-polymeric layer coating carried on by activating and polymeric coating one surface at a time of rigid corrosion-protected flat-rolled sheet metal continuous strip substrate. | 09-25-2008 |
20090042055 | METHODS AND APPARATUS FOR SURFACE PREPARATION AND DUAL POLYMERIC LAYER COATING OF CONTINUOUS-STRIP FLAT-ROLLED SHEET METAL, AND COATED PRODUCT - Processes and apparatus for manufacturing an engineered-composite combining rigid flat-rolled sheet metal continuous-strip and selected polypropylene thermoplastics, which are formulated into dual polymeric coating layers for extrusion deposition, as distinct layers, on a single surface at a time, of continuous-strip, traveling in-line at ambient temperature. Steps for forming a uniform thickness of polymeric layers across strip width, and attraction to an activated metallic surface which provides enhanced adhesion. Solidification of the polymeric layers is augmented by strip temperature during continuous-in-line travel; final dual-surface finishing provides for complete bonding of the polymeric layers on both metallic surfaces. | 02-12-2009 |
Ronald B. Bailey, North East, PA US
Patent application number | Description | Published |
---|---|---|
20090295315 | DYNAMIC BRAKING CIRCUIT FOR A HYBRID LOCOMOTIVE - Methods of dynamic braking include two embodiments with braking circuits for vehicles such as, for example, locomotives which are operable down to very low speeds. These circuits can provide a braking force even at zero locomotive speed. | 12-03-2009 |
Ronald E. Bailey, Pittsburgh, PA US
Patent application number | Description | Published |
---|---|---|
20110067788 | PROCESSES FOR REDUCING FLATNESS DEVIATIONS IN ALLOY ARTICLES - A process for reducing flatness deviations in an alloy article is disclosed. | 03-24-2011 |
20110236721 | STEEL COMPOSITIONS, METHODS OF FORMING THE SAME, AND ARTICLES FORMED THEREFROM - Maraging steel compositions, methods of forming the same, and articles formed therefrom comprising, by weight, 15.0 to 20.0% Ni, 2.0 to 6.0% Mo, 3.0 to 8.0% Ti, up to 0.5% Al, the balance Fe and residual impurities. The composition may be a first layer of a composite plate, and may have a second layer deposited on the first layer, the second layer having a composition comprising, by weight, 15.0 to 20.0% Ni, 2.0 to 6.0% Mo, 1.0 to 3.0 Ti, up to 0.5% Al, the balance Fe and residual impurities. The first layer may have a hardness value ranging from 58 to 64 RC, and the second layer may have a hardness value ranging from 48 to 54 RC. The first layer may be formed employing powdered metallurgical techniques. Articles formed from the compositions include armored plate. | 09-29-2011 |
20120174760 | DUAL HARDNESS STEEL ARTICLE AND METHOD OF MAKING - A dual hardness steel article comprises a first air hardenable steel alloy having a first hardness metallurgically bonded to a second air hardenable steel alloy having a second hardness. A method of manufacturing a dual hard steel article comprises providing a first air hardenable steel alloy part comprising a first mating surface and having a first part hardness, and providing a second air hardenable steel alloy part comprising a second mating surface and having a second part hardness. The first air hardenable steel alloy part is metallurgically secured to the second air hardenable steel alloy part to form a metallurgically secured assembly, and the metallurgically secured assembly is hot rolled to provide a metallurgical bond between the first mating surface and the second mating surface. | 07-12-2012 |
20120183430 | HIGH HARDNESS, HIGH TOUGHNESS IRON-BASE ALLOYS AND METHODS FOR MAKING SAME - One aspect of the present disclosure is directed to low-alloy steels exhibiting high hardness and an advantageous level of multi-hit ballistic resistance with minimal crack propagation imparting a level of ballistic performance suitable for military armor applications. Certain embodiments of the steels according to the present disclosure have hardness in excess of 550 HBN and demonstrate a high level of ballistic penetration resistance relative to conventional military specifications. | 07-19-2012 |
20120321504 | AIR HARDENABLE SHOCK-RESISTANT STEEL ALLOYS, METHODS OF MAKING THE ALLOYS, AND ARTICLES INCLUDING THE ALLOYS - An air hardenable steel alloy is disclosed comprising, in percent by weight: 0.18 to 0.26 carbon; 3.50 to 4.00 nickel; 1.60 to 2.00 chromium; 0 to 0.50 molybdenum; 0.80 to 1.20 manganese; 0.25 to 0.45 silicon; 0 to less than 0.005 titanium; 0 to less than 0.020 phosphorus; 0 up to 0.005 boron; 0 up to 0.003 sulfur; iron; and impurities. The air hardenable steel alloy has a Brinell hardness in a range of 352 HBW to 460 HBW. The air hardenable steel alloy combines high strength, medium hardness and toughness, as compared with certain know air hardenable steel alloys, and finds application in, for example, any of a steel armor, a blast-protective hull, a blast-protective V-shaped hull, a blast-protective vehicle underbelly, and a blast-protective enclosure. | 12-20-2012 |
20130233454 | HIGH HARDNESS, HIGH TOUGHNESS IRON-BASE ALLOYS AND METHODS FOR MAKING SAME - An aspect of the present disclosure is directed to low-alloy steels exhibiting high hardness and an advantageous level of multi-hit ballistic resistance with low or no crack propagation imparting a level of ballistic performance suitable for military armor applications. Various embodiments of the steels according to the present disclosure have hardness in excess of 550 BHN and demonstrate a high level of ballistic penetration resistance relative to conventional military specifications. | 09-12-2013 |
20150275340 | DUAL-PHASE STAINLESS STEEL - A dual-phase ferritic-martensitic stainless steel includes, by weight, about 11.5% to about 12% Cr, about 0.8% to about 1.5% Mn, about 0.75% to about 1.5% Ni, 0% to about 0.5% Si, 0% to about 0.2% Mo, 0% to about 0.0025% B, Fe, and impurities. In various embodiments, the steel has a Brinell hardness (HB) and Charpy V-notch impact energy at −40° C. (CVN) such that CVN (ft-lb)+( | 10-01-2015 |
20150322554 | METHODS FOR MAKING HIGH HARDNESS, HIGH TOUGHNESS IRON-BASE ALLOYS - One aspect of the present disclosure is directed to low-alloy steels exhibiting high hardness and an advantageous level of multi-hit ballistic resistance with minimal crack propagation imparting a level of ballistic performance suitable for military armor applications. Certain embodiments of the steels according to the present disclosure have hardness in excess of 550 HBN and demonstrate a high level of ballistic penetration resistance relative to conventional military specifications. | 11-12-2015 |
Rouse Roby Bailey, New Park, PA US
Patent application number | Description | Published |
---|---|---|
20080265678 | Portable Power Supply - A portable power supply includes a housing, at least one battery cell, and an inverter connected to the at least one battery cell, wherein the inverter outputs at least about 3 kilowatts. A combination power supply and generator is also disclosed. | 10-30-2008 |
20080266913 | Portable Power Supply - A portable power supply includes a housing, and power circuitry providing an output AC waveform having a first positive voltage step level, a second higher positive voltage step level, a third lower positive voltage step level, a fourth negative voltage step level, a fifth higher negative voltage step level, and a sixth lower negative voltage step level. | 10-30-2008 |
R. Roby Bailey, New Park, PA US
Patent application number | Description | Published |
---|---|---|
20080203995 | Methods of discharge control for a battery pack of a cordless power tool system, a cordless power tool system and battery pack adapted to provide over-discharge protection and discharge control - In a cordless power tool system, a battery pack which may removably attachable to a cordless power tool and to a charger may include at least one battery cell and a power limiting device. The power limiting device may be arranged in series with the at least one battery cell for limiting power output of the battery pack based on the component that is connected to the pack. Current and hence power out of the battery pack may be controlled as a function of total internal impedance in the battery pack, which may be adjusted depending on the component that is connected to the pack. | 08-28-2008 |
20080220324 | BATTERY PACK AND INTERNAL COMPONENT ARRANGEMENT WITHIN THE BATTERY PACK FOR CORDLESS POWER TOOL SYSTEM - An internal component arrangement within a battery pack housing having multiple cells and adapted for cordless power tools may provide desired mechanical support to constrain the cells. The housing with internal component arrangement is configured to route sensing wires from the cells to an electronics module of the pack. | 09-11-2008 |
20090146614 | Protection Methods, Protection Circuits and Protection Devices for Secondary Batteries, a Power Tool, Charger and Battery Pack Adapted to Provide Protection Against Fault Conditions in the Battery Pack - In a cordless power tool system, protection methods, circuits and devices are provided to protect against fault conditions within a battery pack that is operatively attached to a power tool or charger, so as to prevent internal or external damage to the battery pack or attached tool or charger. The exemplary methods, circuits and devices address fault conditions such as over-charge, over-discharge, over-current, over-temperature, etc. | 06-11-2009 |
Thomas Bailey, Phoenixville, PA US
Patent application number | Description | Published |
---|---|---|
20110053920 | SUBSTITUTED BICYCLIC PYRIMIDINES - The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted heterobicyclic pyrimidines of Formula (I): | 03-03-2011 |
Thomas R. Bailey, Upper Providence Township, PA US
Patent application number | Description | Published |
---|---|---|
20140296212 | SUBSTITUTED PHENOXYPROPYLCYCLOAMINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS - The present invention provides compounds of formula I: | 10-02-2014 |
Thomas R. Bailey, Phoenixville, PA US
Patent application number | Description | Published |
---|---|---|
20080269333 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS - The present invention provides pharmaceutical compositions useful in treating hepatitis C infection. The present invention also provides methods of treating hepatitis C infection by administering to a mammal the pharmaceutical compositions of the present invention. | 10-30-2008 |
20090203675 | Sulfonyl Semicarbazides, Semicarbazides and Ureas, Pharmaceutical Compositions Thereof, and Methods for Treating Hemorrhagic Fever Viruses, Including Infections Associated with Arena Viruses - Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel semicarbazides, sulfonyl carbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to Arenaviridae (Junin, Machupo, Guanavito, Sabia and Lassa), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever). | 08-13-2009 |
20090281336 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES - The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus. | 11-12-2009 |
20100227892 | Compounds, Compositions and Methods for Treatment and Prevention of Orthopoxvirus Infections and Associated Diseases - Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus. | 09-09-2010 |
20100273779 | Pyridazinone Derivatives - The present invention is directed to novel pyridizinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition. | 10-28-2010 |
20100280007 | Pyridazinone Derivatives - The present invention is directed to novel pyridizinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition. | 11-04-2010 |
20110009456 | Compounds, Compositions and Methods for Treatment and Prevention of Orthopoxvirus Infections and Associated Diseases - Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus. | 01-13-2011 |
20110118505 | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses - Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pinchinde, and VSV), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever). | 05-19-2011 |
20110288075 | Pyridazinone Derivatives - The present invention is directed to novel pyridazinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition/cognitive disorders. | 11-24-2011 |
20120020922 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES - Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus. | 01-26-2012 |
20120022027 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES - Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel semicarbazides, sulfonyl carbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to Arenaviridae (Junin, Machupo, Guanavito, Sabia and Lassa), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever). | 01-26-2012 |
20120238551 | Substituted Phenoxypropylcycloamine Derivatives as Histamine-3 (H3) Receptor Ligands - The present invention provides compounds of formula I: | 09-20-2012 |
20120295882 | Tricyclic Derivatives and Their Pharmaceutical Use and Compositions - This application relates to tricyclic compounds of Formula I: | 11-22-2012 |
20130261087 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENA VIRUSES - Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pinchinde, and VSV), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever). | 10-03-2013 |
20130345278 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES - Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus. | 12-26-2013 |
20140142088 | PYRIDAZINONE DERIVATIVES - The present invention is directed to novel pyridazinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition. | 05-22-2014 |
20140275037 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES - Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel semicarbazides, sulfonyl carbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to Arenaviridae (Junin, Machupo, Guanavito, Sabia and Lassa), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever). | 09-18-2014 |
20140316145 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES - Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus. | 10-23-2014 |
20140378681 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS,PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES - Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel semicarbazides, sulfonyl carbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to Arenaviridae (Junin, Machupo, Guanavito, Sabia and Lassa), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever). | 12-25-2014 |
Wendy J. Bailey, Fort Washington, PA US
Patent application number | Description | Published |
---|---|---|
20090298073 | Kidney Toxicity Biomarkers - Novel biomarkers for kidney toxicity. Said biomarkers may be useful for optimization of lead compounds, or in safety assessment. | 12-03-2009 |