Aurelia
Aurelia Boulaflous, Mont Saint Aignan Cedex FR
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20110195452 | SET OF SEQUENCES FOR TARGETING EXPRESSION AND CONTROL OF THE POST-TRANSLATIONAL MODIFICATION OF A RECOMBINANT POLYPEPTIDE - The present invention provides new tools useful for controlling the post-translational modifications of recombinant polypeptides. These tools are particular signal peptides allowing the targeting of recombinant polypeptides during their synthesis in a host cell to specific sub-cellular compartments and a specific designing of said recombinant polypeptides within said sub-cellular compartments. These signal peptides are SEQ ID no 1 to SEQ ID no 31 disclosed herein. The present invention relates therefore also to a process for producing a recombinant polypeptide, in particular to a post-translationally modified polypeptide comprising the steps of transfecting or transforming a cell with at least one numleic acid vector encoding a recombinant protein which is the polypeptide before being post-translationally modified or a recombinant protein different to said polypeptide, said recombinant protein comprising a peptide signal according to the present invention; growing the transfected cell; and harvesting the post-translationally modified polypeptide; wherein, when said recombinant protein is different to said polypeptide, the method also comprises a step of transfecting said cell with at least one vector encoding said polypeptide. The present invention allows advantageously, for example, to increase the yield of production of recombinant polypeptides, to prevent immunogenicity if recombinant polypeptides and to obtain therapeutically active recombinant polypeptides that are the exact copy of their natural counterpart. This invention relates particularly to the field of reorientation of plants made pharmaceuticals (PMP). | 08-11-2011 |
Aurelia Buzgau, Chicago, IL US
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20090159604 | Drinking vessel sanitary device - A sanitary shield is provided for use with drinking vessels having a rim configured for contact with the mouth of an individual drinking from the vessel, with the rim located between the interior of the vessel and the exterior of the vessel. The shield includes a disposable, flexible member having a size and shape adapted and constructed to cover the rim of the vessel, a portion of the interior of the vessel, and a portion of the exterior of the vessel. The flexible member is fabricated from a material that is self-adherent to the vessel. The shield prevents the mouth of an individual drinking from the vessel from coming into contact with any portion of the exterior surface of the vessel during normal drinking activity. | 06-25-2009 |
Aurelia Cheng, Berkeley, CA US
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20110073805 | Novel compositions and methods useful for ionic liquid treatment of biomass - The present invention provides for novel compositions and methods for recycling or recovering ionic liquid used in IL pretreated cellulose and/or lignocellulosic biomass (LBM). | 03-31-2011 |
Aurelia De La Cuesta Sheppard, Newtown, PA US
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20130303674 | POWERFEED POLYMERS HAVING IMPROVED BLOCK RESISTANCE PERFORMANCE - The present invention provides emulsion copolymers and coating compositions containing the same having improved room temperature and hot block resistance in coatings wherein the copolymers have a broad measured glass transition temperature and are the copolymerization product of a vinyl monomer composition A and a softer vinyl monomer composition B having a Hansch parameter of at least 3.2, and containing one or more vinyl monomer M, such that each of which vinyl monomer(s) M would when homopolymerized provide a homopolymer having a measured Tg of 20° C. or less, such as, for example, 2-ethylhexyl acrylate. In addition, the present invention provides methods for making the emulsion copolymers by a powerfeed process comprising feeding vinyl monomer composition A into a reactor from a feed vessel while feeding, simultaneously or after a delay, vinyl monomer composition B into the feed vessel while polymerizing the monomers in the reactor. | 11-14-2013 |
Aurelia Dodoc, Oberkochen DE
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20080259441 | Imaging System - An imaging system for imaging an object field arranged in an object surface of the imaging system onto an image field arranged in an image surface of the optical system while creating at least one intermediate image including: a first imaging subsystem for creating the intermediate image from radiation coming from the object surface, the first imaging subsystem having a first optical axis; and a second imaging subsystem different in construction from the first imaging subsystem for imaging the intermediate image onto the image surface, the second imaging subsystem having a second optical axis; wherein the first optical axis is offset with respect to the second optical axis by an axis offset at the intermediate image and wherein the intermediate image has a correction status adapted to the axis-offset such that the correction status of the image field is essentially free from aberrations caused by the axis-offset. | 10-23-2008 |
Aurelia Douard, Bethune FR
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20090324822 | METHOD FOR DEPOSITING HARD METALLIC COATINGS - A method for depositing a hard metallic chrome coating or similar metal by chemical vapor deposition on a metallic substrate, includes: a) preparing a solution containing, in an oxygen atom depleted solvent, i) a molecular compound of the bis(arene) family that's a precursor of the deposited metal with a decomposition temperature 300° C.-550° C., and ii) a chlorinated additive; b) introducing the solution as aerosol into a heated evaporator at a temperature between the solvent boiling temperature and the precursor decomposition temperature (PDT); and c) driving the vaporized aerosol from the evaporator towards a CVD reactor including a susceptor carrying the substrate, heated above the PDT, up to 550° C., the evaporator and CVD reactor being subjected to atmospheric pressure. This DLI-CVD method performed at low temperature and atmospheric pressure enables continuous industrial treatment of large metallic plates, producing hard, monolayer or nanostructured multilayer metallic coatings. An appropriate injectable solution is also described. | 12-31-2009 |
20100047449 | PROCESS FOR DEPOSITION OF NON-OXIDE CERAMIC COATINGS - A method for depositing a non-oxide ceramic-type coating based on chrome carbides, nitrides or carbonitrides, by DLI-CVD at low temperature and atmospheric pressure on a metallic substrate, includes: a) a solution is prepared, containing a molecular compound which is a precursor of the metal to be deposited, belongs to the bis(arene) family, and has a decomposition temperature of 300° C.-550° C., the compound being dissolved in an oxygen atom depleted solvent; b) the solution is introduced as aerosol into a heated evaporator at a temperature between the solvent boiling temperature and the precursor decomposition temperature; and c) the precursor and the vaporized solvent are driven from the evaporator towards a CVD reactor having cold walls, with a susceptor carrying the substrate to be covered and heated to a temperature higher than the decomposition temperature of the precursor, to a maximum of 550° C., the evaporator and the CVD reactor being at atmospheric pressure. | 02-25-2010 |
Aurelia Ferrigato, Trecate IT
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20120041224 | Process For The Iodination Of Aromatic Compounds - The present invention relates to a process for the preparation of iodinated anilines; in particular, it relates to a process including the direct iodination, with suitably activated iodine, of 3,5-disubstituted anilines to the corresponding 3,5-disubstituted-2,4,6-triiodoanilines, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves. | 02-16-2012 |
20120232151 | Process for the Preparation of Gadobenate Dimeglumine Complex in a Solid Form - The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions. | 09-13-2012 |
Aurelia Koby, Poway, CA US
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20110313335 | THERAPY DEVICE AND METHODS OF USE THEREOF - A therapy device for alleviating arm and shoulder pain and methods of use thereof is disclosed. In one embodiment, the therapy device is an arm sling with an adjustable, pressure-relieving neck strap. The arm sling may optionally include a squeezable pouch removably attached thereto. The squeezable pouch may be squeezed in the hand and/or manipulated by the fingers to either help relieve stress and muscle tension or to exercise the muscles of the hand. | 12-22-2011 |
Aurelia Koby, San Diego, CA US
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20080249450 | KNEE SUPPORT DEVICE - Broadly, the present invention is a knee support device for providing focused and comfortable pressure (i.e. conforms to the size and shape of the knee and patella) to reduce knee pain. The knee support device comprises a stretchable band for encircling a portion of the user's leg. A moldable inner support is secured to the inner surface of the band and is filled with beads allowing the moldable inner support to conform to the specific anatomy of the user's knee for maximum support and relief. The moldable inner support is only affixed to the band at its ends so that it may move freely with respect to the band and also provides focused pressure to reduce knee pain and helps stabilize the patella to improve alignment and tracking. | 10-09-2008 |
20100022930 | WRIST SUPPORT DEVICE - A wrist support sleeve is adapted to extend over a wearer's hand and wrist from a location below the ends of the fingers tip to a position just past the wrist region. The sleeve has an opening for receiving the wearer's thumb. A first portion of the sleeve extends around the lower part and opposite sides of a wearer's hand and wrist and has spaced side edges located in an upper region of the sleeve. An insert panel of a different material to the first sleeve portion is secured between spaced side edges of the first portion, so as to extend across the tipper portion of a wearer's hand and wrist when the device is worn. The insert panel material is a strong elastic material which has a higher stiffness than the rest of the sleeve. | 01-28-2010 |
Aurelia Lappert, Woluwe Saint Pierre BE
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20150290142 | Multi-Day Patch for the Transdermal Administration of Rotigotine - The present invention relates to a transdermal therapeutic system, comprising (a) a backing layer, (b) a solvent-based self-adhesive matrix layer containing rotigotine as active ingredient, and (c) a release liner, wherein the self-adhesive matrix layer has a coating weight of about 75-400 g/m | 10-15-2015 |
Aurelia Liar, Achern DE
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20150041497 | Container For Dispensing A Flowable Substance - A container for dispensing a flowable substance, in particular glue, such as instant glue, includes a receiving body which has a circumferential wall and a main axis extending in the longitudinal direction of the receiving body. The bottom of the receiving body is formed either by a plug inserted into an open end of the receiving body or by an end wall formed integrally on the circumferential wall. A nozzle or dispensing tip for discharging the flowable substance is arranged at an end side of the receiving body facing away from the receiving body bottom. The nozzle or dispensing tip has an outlet opening. A lever is arranged on the circumferential wall and extends along the main axis forming an acute angle with the circumferential wall so that a slit-like intermediate space is formed. | 02-12-2015 |
Aurelia Meloni-Ehrig, Gainesville, VA US
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20100304390 | METHODS FOR DETECTING GENE DYSREGULATIONS - Described herein are methods, compositions and kits directed to the detection of gene dysregulations such as those arising from gene fusions and/or chromosomal abnormalities, e.g. translocations, insertions, inversions and deletions. Samples containing dysregulated gene(s) of interest may show independent expression patterns for the 5′ and 3′ regions of the gene. The methods, compositions and kits are useful for detecting mutations that cause the differential expression of a 5′ portion of a target gene relative to the 3′ region of the target gene. | 12-02-2010 |
20130316341 | METHODS FOR DETECTING GENE DYSREGULATIONS - Described herein are methods, compositions and kits directed to the detection of gene dysregulations such as those arising from gene fusions and/or chromosomal abnormalities, e.g., translocations, insertions, inversions and deletions. Samples containing dysregulated gene(s) of interest may show independent expression patterns for the 5′ and 3′ regions of the gene. The methods, compositions and kits are useful for detecting mutations that cause the differential expression of a 5′ portion of a target gene relative to the 3′ region of the target gene. | 11-28-2013 |
20130330719 | EML4-ALK TRANSLOCATIONS IN LUNG CANCER - The present disclosure relates to methods for the diagnosis and evaluation of neoplastic disorders, particularly non-small cell lung cancer. Assays are described in which patient test samples are analyzed for the presence of one or more specific EML4-ALK fusion genes associated with neoplastic disorders. | 12-12-2013 |
20150038367 | METHODS FOR DETECTING GENE DYSREGULATIONS - Described herein are methods, compositions and kits directed to the detection of gene dysregulations such as those arising from gene fusions and/or chromosomal abnormalities, e.g., translocations, insertions, inversions and deletions. Samples containing dysregulated gene(s) of interest may show independent expression patterns for the 5′ and 3′ regions of the gene. The methods, compositions and kits are useful for detecting mutations that cause the differential expression of a 5′ portion of a target gene relative to the 3′ region of the target gene. | 02-05-2015 |
Aurelia Plihon, Villach AT
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20120085372 | METHOD FOR DRYING A SEMICONDUCTOR WAFER - Disclosed is a method for drying a plate-like article; the method including rinsing with an aqueous rinsing liquid with subsequent rinsing with an organic solvent, | 04-12-2012 |
Aurelia Reckziegel, Dormagen DE
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20080319244 | Method for the Production of (E,Z)-7,8-Cyclohexadecene-1-one - A process for the preparation of a (E,Z)-7,8-cyclohexadecen-1-one isomeric mixture is described, comprising the following step: | 12-25-2008 |
20090018051 | USES OF (Z)-1-(3-METHYL-BUT-2-ENYLOXY)-HEX-3-ENE - The use of (Z)-1-(3-methylbut-2-enyloxy)hex-3-ene, or a mixture containing (Z)-1-(3-methylbut-2-enyloxy)hex-3-ene, as an agent for providing (a) hair or (b) textile fibres with a fresh-green smell is described. | 01-15-2009 |
20100130397 | 4-Isoamylcyclohexanol as Odiferant - The use of | 05-27-2010 |
Aurelia Safta, Walnut Creek, CA US
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20090148435 | ANTIBODY PURIFICATION BY CATION EXCHANGE CHROMATOGRAPHY - A method for purifying an antibody by cation exchange chromatography is described in which a high pH wash step is used to remove of contaminants prior to eluting the desired antibody using an elution buffer with increased conductivity. | 06-11-2009 |
20150056196 | ANTIBODY PURIFICATION BY CATION EXCHANGE CHROMATOGRAPHY - A method for purifying an antibody by cation exchange chromatography is described in which a high pH wash step is used to remove of contaminants prior to eluting the desired antibody using an elution buffer with increased conductivity. | 02-26-2015 |
Aurelia Seon, Mulhouse FR
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20090142802 | POLYPEPTIDES AND NUCLEIC ACIDS ENCODING SAME - The present invention relates to isolated polypeptides and isolated nucleic acid sequences encoding the polypeptides, as well as methods for producing and using the polypeptides in animal feed. An example of a polypeptide of the invention is the so-called L12 protein from | 06-04-2009 |
20100010232 | Aryl derivatives of curcumin, demethoxycurcumin, bisdemethoxycurcumin or curcuminisoxazolide and their use as animal feed additives - The present invention relates to the use of acyl derivatives of curcumin, desmethoxy curcumin and bisdesmethoxy curcumin and of curcuminisoxazolide as components of animal feed or feed additives for the improvement of animal performance and the new acyl derivatives per se as well as the corresponding animal feed or feed additives containing them. | 01-14-2010 |
20100119646 | Dihydroeugenol as Additive for feed - The present invention relates to the use of a selected group of phenol derivatives as components of animal feed or feed additives for the improvement of animal performance as well as to the corresponding animal feed or feed additives containing them. | 05-13-2010 |
20100285171 | POLYPEPTIDES AND NUCLEIC ACIDS ENCODING SAME - The present invention relates to isolated polypeptides and isolated nucleic acid sequences encoding the polypeptides, as well as methods for producing and using the polypeptides in animal feed. An example of a polypeptide of the invention is the so-called L12 protein from | 11-11-2010 |
20110189347 | USE OF SUCCINIC ACID - This invention relates to a composition comprising Succinic Acid or a derivative thereof. It has been surprisingly found that Succinic Acid and derivatives thereof have a great potential for use in animal feed, e.g. for improving the feed conversion ratio (FCR) and/or for modulation of the gut flora. It is therefore the main object of the present invention to provide compositions and methods for the use of Succinic Acid in animal feed. | 08-04-2011 |
Aurelia Séon, Mulhouse FR
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20120295000 | Polypeptides and Nucleic Acids Encoding Same - The present invention relates to isolated polypeptides and isolated nucleic acid sequences encoding the polypeptides, as well as methods for producing and using the polypeptides in animal feed. An example of a polypeptide of the invention is the so-called L12 protein from | 11-22-2012 |
Aurelia Stellmach-Hanulok, Wuelfrath DE
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20130118274 | WATER ANALYSIS SENSOR CARTRIDGE WITH TRANSPORT CONTAINER - A transport container system for a water analysis sensor cartridge includes a water analysis sensor cartridge configured to be interchangeable. The water analysis sensor cartridge comprises at least two different sensor membranes. A transport container cup comprises, for each of the at least two different sensor membranes, a separate moist chamber. Each separate moist chamber comprises one chamber opening and a specific humectant for each of the at least two different sensor membranes. | 05-16-2013 |
20130168245 | WATER ANALYSIS SENSOR ELECTRODE - A water analysis sensor electrode for determining an analyte in water includes a sensor electrode housing which is configured to be closed. The sensor electrode housing comprises an inner wall and an ion-selective sensor electrode diaphragm arranged at a lower distal end of the sensor electrode housing. An electrolyte solution is in the sensor electrode housing. A measuring electrode is arranged in the sensor electrode housing. A gas bubble is enclosed by the sensor electrode housing. A rigid rod element having a round cross section is arranged in the sensor electrode housing so that a continuous open capillary channel extends over a length of the sensor electrode housing between the rigid rod element and the inner wall. | 07-04-2013 |
Aurelia Suwarno-Handayana, Hopewell Junction, NY US
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20120027956 | MODIFICATION OF NITRIDE TOP LAYER - A method of forming a nitride film is disclosed. In one embodiment, the method comprises performing an ending film deposition process that differs from the main film deposition process in terms of the flow rates of the reactive and ion source gases, and maintaining acceleration power of a CVD tool during the ending film deposition process. A post deposition process may also be used to remove a denser top layer of nitride, resulting in a nitride film having a consistent density. | 02-02-2012 |