Patent application number | Description | Published |
20110060334 | Apparatus and Method of Controlling Cutting Blade Travel Through the Use of Etched Features - A forceps includes a housing including a shaft. The shaft includes an end effector assembly having a pair of curved jaw members. The jaw members include an electrically conductive surface and a curved blade channel having opposing sidewalls. A cutting blade is configured for translation within the blade channel. Proximal portions of a first sidewall include incident angles of less than five degrees that engage the cutting blade and direct the blade towards a specific point of contact on the opposing sidewall of the curved blade channel. | 03-10-2011 |
20110072638 | Method and System for Manufacturing Electrosurgical Seal Plates - A method of manufacture for an end effector assembly is provided. The method includes providing a pair of jaw members. A step of the method includes forming one or more seal plates positionable on one of the pair of jaw members. Etching a dam along a side of the one or more seal plates is a step of the method, wherein the etched dam inhibits the flow of a plastic on the one or more seal plate such that a height of the plastic with respect to the at least one seal plate during an overmolding process may be controlled. The method includes positioning the one or more seal plates on the one of the pair of jaw members; and overmolding the seal plate to one or more of the pair of jaw members. | 03-31-2011 |
20110073246 | Method and System for Manufacturing Electrosurgical Seal Plates - A method of manufacture for an end effector assembly is provided. The method includes providing a pair of jaw members. A step of the method includes forming one or more seal plates positionable on one of the pair of jaw members. Etching a dam along a side of the one or more seal plates is a step of the method, wherein the etched dam inhibits the flow of a plastic on the one or more seal plate such that a height of the plastic with respect to the at least one seal plate during an overmolding process may be controlled. The method includes positioning the one or more seal plates on the one of the pair of jaw members; and overmolding the seal plate to one or more of the pair of jaw members. | 03-31-2011 |
20120118507 | System for Manufacturing Electrosurgical Seal Plates - A system for the manufacture of an end effector assembly which is configured for use with an electrosurgical instrument configured for performing an electrosurgical procedure is provided. The system includes a photolithography module that is configured to etch one or more pockets on a seal surface of the seal plate. A vacuum module is configured to raise, transfer and lower a spacer from a location remote from the pocket(s) on the seal plate to the pocket on the seal plate(s). An adhesive dispensing module is configured to dispense an adhesive into the pocket on the seal plate. An optical module is configured to monitor a volume of the adhesive dispensed within the pocket and monitor placement of the spacer within the pocket. | 05-17-2012 |
20130226177 | Vessel Sealing Instrument with Reduced Thermal Spread and Method of Manufacture Therefor - An electrosurgical vessel sealing instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes a jaw housing, a seal plate having a tissue contacting surface and a side wall, and an insulating region disposed on the side wall of the seal plate. The instrument includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The insulating region enables precision overmolding of the jaw housing to the seal plate, while advantageously reducing thermal spread and edge cutting during vessel sealing procedures. | 08-29-2013 |
20130226178 | Vessel Sealing Instrument with Reduced Thermal Spread and Method of Manufacture Therefor - An electrosurgical vessel sealing instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes a jaw housing, an inner tissue engaging surface, and an insulating layer disposed therebetween. The instrument includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The jaws include a tissue-contacting seal plate having obverse and reverse surfaces. A series of ribs extend from the reverse surface of the seal plate into an insulating layer, which, in turn, is affixed to a jaw housing. The ribbed structure of the seal plate reduces thermal spread and edge cutting during vessel sealing procedures, leading to improved surgical outcomes. | 08-29-2013 |
20150073411 | VESSEL SEALING INSTRUMENT WITH REDUCED THERMAL SPREAD AND METHOD OF MANUFACTURE THEREFOR - An electrosurgical vessel sealing instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes a jaw housing, a seal plate having a tissue contacting surface and a side wall, and an insulating region disposed on the side wall of the seal plate. The instrument includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The insulating region enables precision overmolding of the jaw housing to the seal plate, while advantageously reducing thermal spread and edge cutting during vessel sealing procedures. | 03-12-2015 |
20150083688 | SYSTEM FOR MANUFACTURING ELECTROSURGICAL SEAL PLATES - A system for the manufacture of an end effector assembly which is configured for use with an electrosurgical instrument configured for performing an electrosurgical procedure is provided. The system includes a photolithography module that is configured to etch one or more pockets on a seal surface of the seal plate. A vacuum module is configured to raise, transfer and lower a spacer from a location remote from the pocket(s) on the seal plate to the pocket on the seal plate(s). An adhesive dispensing module is configured to dispense an adhesive into the pocket on the seal plate. An optical module is configured to monitor a volume of the adhesive dispensed within the pocket and monitor placement of the spacer within the pocket. | 03-26-2015 |
20150223861 | VESSEL SEALING INSTRUMENT WITH REDUCED THERMAL SPREAD AND METHOD OF MANUFACTURING THEREFOR - An electrosurgical vessel sealing instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes a jaw housing, an inner tissue engaging surface, and an insulating layer disposed therebetween. The instrument includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The jaws include a tissue-contacting seal plate having obverse and reverse surfaces. A series of ribs extend from the reverse surface of the seal plate into an insulating layer, which, in turn, is affixed to a jaw housing. The ribbed structure of the seal plate reduces thermal spread and edge cutting during vessel sealing procedures, leading to improved surgical outcomes. | 08-13-2015 |
20150223867 | TEMPERATURE-SENSING ELECTRICALLY-CONDUCTIVE TISSUE-CONTACTING PLATE AND METHODS OF MANUFACTURING SAME - An end-effector assembly includes opposing jaw members movably mounted with respect to one another. At least one of the jaw members includes a temperature-sensing electrically-conductive tissue-contacting plate having a tissue-contacting surface and a bottom surface. A first layer is disposed on one or more portions of the bottom surface of the temperature-sensing electrically-conductive tissue-contacting plate. The first layer includes an electrically-insulative material. One or more openings are formed in the first layer. One or more electrically-conductive traces are formed over the electrically-insulative material and associated with the one or more openings. One or more temperature sensors are coupled to the bottom surface of the temperature-sensing electrically-conductive tissue-contacting plate and associated with the one or more openings. The one or more openings are each configured to receive at least a portion of the one or more temperature sensors therein. The one or more temperature sensors are electrically coupled to the one or more electrically-conductive traces. | 08-13-2015 |
20150223868 | TEMPERATURE-SENSING ELECTRICALLY-CONDUCTIVE TISSUE-CONTACTING PLATE CONFIGURED FOR USE IN AN ELECTROSURGICAL JAW MEMBER, ELECTROSURGICAL SYSTEM INCLUDING SAME, AND METHODS OF CONTROLLING VESSEL SEALING USING SAME - An electrosurgical system includes an electrosurgical instrument, an electrosurgical power generating source, and a controller. The electrosurgical instrument includes a shaft extending from a housing. The shaft includes a distal end configured to support an end-effector assembly. The end-effector assembly includes opposing jaw members movably mounted with respect to one another and moveable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween. At least one of the jaw members includes a temperature-sensing electrically-conductive tissue-contacting plate defining a bottom surface. One or more temperature sensors are coupled to the bottom surface. The controller is configured to control one or more operating parameters associated with the electrosurgical power generating source based on one or more signals indicative of a tissue impedance value and indicative of a temperature sensed by the one or more temperature sensors. | 08-13-2015 |
20160038226 | VESSEL SEALING INSTRUMENT WITH REDUCED THERMAL SPREAD AND METHOD OF MANUFACTURE THEREFOR - An electrosurgical vessel sealing instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes a jaw housing, a seal plate having a tissue contacting surface and a side wall, and an insulating region disposed on the side wall of the seal plate. The instrument includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The insulating region enables precision overmolding of the jaw housing to the seal plate, while advantageously reducing thermal spread and edge cutting during vessel sealing procedures. | 02-11-2016 |
Patent application number | Description | Published |
20120316151 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS - This invention relates to the use of triazolone derivatives of Formula (I) for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer. | 12-13-2012 |
20130029938 | Chemical Compounds - Compounds of Formula I and methods for treating metabolic disorders are disclosed. | 01-31-2013 |
20130172384 | FATTY ACID SYNTHASE INHIBITORS - This invention relates to the use of triazolone and triazolethione derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones and triazolethiones in the treatment of cancer. | 07-04-2013 |
20130196971 | FATTY ACID SYNTHASE INHIBITORS - This invention relates to the use of imidazole, triazole, and tetrazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of imidazoles, triazoles, and tetrazoles in the treatment of cancer. | 08-01-2013 |
20140100213 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS - This invention relates to the use of triazolone derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer. | 04-10-2014 |
Patent application number | Description | Published |
20090053172 | HETEROCYCLIC COMPOUNDS AS CCR5 ANTAGONISTS - The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). | 02-26-2009 |
20090187021 | INDANE COMPOUNDS AS CCR5 ANTAGONISTS - The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). | 07-23-2009 |
Patent application number | Description | Published |
20100174051 | Asymmertric porous adsorptive bead - The present invention relates to an asymmetric chromatography media suitable for separations applications, particularly as packed bed, fluidized bed or magnetized bed chromatography media. In certain embodiments, the asymmetric chromatography media comprises asymmetric particles, preferably beads, having at least two distinct, controlled pore size distributions. Preferably one of the distinct pore size distributions is in an internal region of the particle, and the other is in an external region or coating on the particle. These distinct pore size distributions can be modified with uniform or alternatively unique functional groups or mixtures of functional groups. The present invention allows for the control over pore size distribution within an asymmetric porous particle by providing a distinct internal region, preferably in the form of a bead, and a distinct external region, preferably in the form of a coating on the bead. | 07-08-2010 |
20140073769 | ASYMMETRIC POROUS ADSORPTIVE BEAD - The present invention relates to an asymmetric chromatography media suitable for separations applications, particularly as packed bed, fluidized bed or magnetized bed chromatography media. In certain embodiments, the asymmetric chromatography media comprises asymmetric particles, preferably beads, having at least two distinct, controlled pore size distributions. Preferably one of the distinct pore size distributions is in an internal region of the particle, and the other is in an external region or coating on the particle. These distinct pore size distributions can be modified with uniform or alternatively unique functional groups or mixtures of functional groups. The present invention allows for the control over pore size distribution within an asymmetric porous particle by providing a distinct internal region, preferably in the form of a bead, and a distinct external region, preferably in the form of a coating on the bead. | 03-13-2014 |
Patent application number | Description | Published |
20140013495 | UNOBTRUSIVE HIGH-END READY TO WEAR BODY ARMOR GARMENT - This invention is a torso-body shaped frame vest-like garment that is designed to function as ballistic armor. This garment contains inserts comprised of unitary panels of pliable ballistic material capable of stopping bullets from most handguns. The use of a torso pattern sloper as a base structure for frame design allows this garment to be adapted for all types of wearable apparel besides vests such as jackets, coats, suits, shirts, etc., and allows for an increased range of movement and level of comfort. Unlike most other types of ballistic armor that is concealed by being worn under normal clothing this garment is designed to be used as outerwear that can complement casual, business, or other professional attire. Its function as fashionable, concealable, and comfortable ballistic armor is achieved by using design methods, sewing techniques, ornamental trim applications, and fabric applications common to high fashion casual and professional attire. | 01-16-2014 |
20140150154 | Unobtrusive high-end ready to wear concealable body armor - A bullet resistant garment is provided for in the current invention having a pliable protective insert contained within a concealed carrier shell that is integrated into an outer-garment. In certain embodiments, interconnecting seams and or darts may be incorporated into the pliable protective insert and/or carrier shell to provide a comfortable and protective three-dimensional shape to bullet resistant garment, especially for women. | 06-05-2014 |
20150059042 | UNOBTRUSIVE HIGH-END READY TO WEAR BODY ARMOR GARMENT - A bullet resistant garment is provided for in the current invention having a pliable protective insert contained within a concealed carrier shell that is integrated into an outer-garment. In certain embodiments, interconnecting seams and or darts may be incorporated into the pliable protective insert and/or carrier shell to provide a comfortable and protective three-dimensional shape to bullet resistant garment, especially for women. | 03-05-2015 |
Patent application number | Description | Published |
20080283177 | Tensioning device for composite structures - An apparatus to prepare a preform for fabrication includes a mandrel, anchoring groove, anchoring device, tensioning groove, and tensioning device. The mandrel receives the preform. The mandrel has a first mandrel end and a second mandrel end. The preform has a first preform end and a second preform end. The anchoring groove is disposed at the first mandrel end. The anchoring device is configured and located to urge the first preform end towards the anchoring groove to secure the first preform end therebetween. The tensioning groove is disposed between the first mandrel end and the second mandrel end. The tensioning device is configured and located to urge a portion of the preform into the tensioning groove. | 11-20-2008 |
20100040722 | Bulk Resin Infusion System Apparatus and Method - A composite item is fabricated in system that includes a layer of preform, supply of resin, mandrel, and bagging film. The layer of preform corresponds to the composite item. The supply of resin is sufficient to infuse the preform. The mandrel includes a preform receiving zone to receive the layer of preform and a resin receiving zone to receive the supply of resin. The resin receiving zone is adjacent to the preform receiving zone. The bagging film is operable to generate an envelope surrounding the preform receiving zone and the resin receiving zone. | 02-18-2010 |
20120263818 | DEVICE FOR TENSIONING A PREFORM - An apparatus for tensioning a preform may include a mandrel to receive a preform. The mandrel may have a first mandrel end and a second mandrel end. The preform may have a first preform end and a second preform end. The apparatus may include an anchoring groove disposed at the first mandrel end, and an anchoring device being configured and located to urge the first preform end towards the anchoring groove to secure the first preform end therebetween. The apparatus may include a tensioning groove disposed between the first mandrel end and the second mandrel end, and a tensioning device being configured and located to urge at least a portion of the preform into the tensioning groove. | 10-18-2012 |
20150107775 | Vacuum Bag Sealing System and Method for Composite Parts - A vacuum bag sealing system may include a composite bagging sheet, and at least one interlocking strip connected to a surface of the composite bagging sheet, wherein the interlocking strip is configured to join a first section of the composite bagging sheet to a second section of the composite bagging sheet to form a sealed vacuum bag. | 04-23-2015 |