Anne M.
Anne M. Bowcock, St. Louis, MO US
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20120077682 | COMPOSITIONS AND METHODS FOR DETECTING CANCER METASTASIS - The present invention encompasses compositions and methods for detecting cancer metastasis. | 03-29-2012 |
Anne M. Gillis, Calgary CA
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20100069982 | TIME BASED ARRHYTHMIA THERAPY EFFICACY CRITERIA - An implantable medical device and associated method classify therapy outcomes and heart rhythms in association with therapy outcome. A therapy success time interval is started in response to delivering an arrhythmia therapy. If normal sinus rhythm is detected after the therapy success time interval expires, the delivered therapy is classified as unsuccessful and the detected arrhythmia is classified as a self-terminating rhythm. | 03-18-2010 |
Anne M. Kelly-Rowley, Midland, MI US
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20130123385 | DYE-ENCAPSULATED DISPERSIONS SUITABLE FOR PRINTING APPLICATIONS - The instant invention provides dye-encapsulated dispersions suitable for printing applications, method of producing the same, ink compositions made therefrom, delivery systems for such ink compositions, and articles having a coating layer derived from such ink compositions. | 05-16-2013 |
20140241972 | ENVIRONMENTALLY FRIENDLY METHODS OF PREPARING MESOPOROUS SILICEOUS STRUCTURES - A process for preparing structures of crosslinked silicon oxide which are mesoporous structures wherein, a portion of the materials used in the preparation of the structures are recycled for use in the preparation of additional structures. | 08-28-2014 |
20140295165 | HIGH POROSITY MESOPOROUS SILICEOUS STRUCTURES - A process comprising: A) contacting one or more of sources of silicon oxide, selected from water sol-uble.silica sources arid alkali metal silicates, with an aqueous reaction medium, comprising one or more nonionic surfactants and thereby forming mesoporous structures comprising crosslinked silicon oxide units, wherein said cross-linked silicon oxide units have pores of about 1 to about 100 nanometers and wherein the aqueous reaction medium exhibits a pH of about 0 to about 4.0; B) exposing the aqueous reaction medium containing the mesoporous structures to elevated temperatures for a time sufficient to achieve the desired structure and pore size. Preferred water soluble silica sources comprise silicic acid, or po!ysilicic acids, The aqueous reaction, medium is prepared by combining one or more nonionic surfactants and water, theteby forming an aqueous, reaction medium. comprising micelles. Preferably, the aqueous reaction medium further comprises, a. micelle swelling agent capable of swelling micelles formed by the surfactant in the aqueous reaction medium. In one embodiment the process forms structures with struts comprised of crosslinked silicon oxides which connect at least some of the pore forming structures. | 10-02-2014 |
Anne M. Kumor, Greendale, WI US
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20110087988 | GRAPHICAL CONTROL ELEMENTS FOR BUILDING MANAGEMENT SYSTEMS - A building management system includes graphical control elements for viewing and interacting with the building management system. Graphical control elements conduct analysis of information received from the building management system and may be used to control building equipment, monitor operational statuses, diagnose faults, or conduct other building management system tasks. | 04-14-2011 |
Anne M. Lemoigne, Ann Arbor, MI US
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20090240418 | DUAL THROTTLE POSITION SENSOR DIAGNOSTIC SYSTEM WITH REDUCED STALLING - A system includes an out of correlation (OOC) detection module that detects an OOC error between a first throttle position sensor (TPS) and a second TPS. An out of range (OOR) detection module that detects first and second OOR errors for the first and second TPS, respectively. An OOC counter sets an OOC error when an OOC count is greater than or equal to a first OOC value. An OOR counter sets first and second OOR errors when first and second OOR counts, respectively, are greater than or equal to a second OOR value that is less than the first OOC value. A control module increments the counters when the respective errors occur and sets at least one of the first and second OOR counts equal to the OOC count when at least one of the first and second OOR errors occur after the OOC error. | 09-24-2009 |
Anne M. Meunch, Oshkosh, WI US
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20150332617 | EDGE HAZARD WARNING DEVICE - The present invention provides a device for displaying hazard indicia, having a stanchion defining a first end and a second end, whereby the first end defines a first cross section that is smaller than a second cross section of the second end; a base adapted to removably receive the second end of the stanchion so as to maintain the stanchion in a vertical position; and a means for allowing the device to be collinearly stacked on top of a second device such that only the second end of the device and the second end of the second device contact. | 11-19-2015 |
Anne M. Pedata, Tucson, AZ US
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20130109019 | HAPTEN CONJUGATES FOR TARGET DETECTION | 05-02-2013 |
20130260379 | SIGNALING CONJUGATES AND METHODS OF USE - Disclosed herein are embodiments of a signaling conjugate, embodiments of a method of using the signaling conjugates, and embodiments of a kit comprising the signaling conjugate. The disclosed signaling conjugate comprises a latent reactive moiety and a chromogenic moiety that may further comprise a linker suitable for coupling the latent reactive moiety to the chromogenic moiety. The signaling conjugate may be used to detect one or more targets in a biological sample and are capable of being covalently deposited directly on or proximally to the target. Particular disclosed embodiments of the method of using the signaling conjugate comprise multiplexing methods. | 10-03-2013 |
Anne M. Pentz, Landenberg, PA US
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20080280370 | METHODS AND COMPOSITIONS FOR DETECTING GLYPHOSATE AND METABOLITES THEREOF - The present invention provides various methods and compositions which allow for determining the presence or amount of glyphosate, N-acetylglyphosate, N-acetyl AMPA or aminomethyl phosphoric acid (AMPA) and its various metabolites in a variety of test matrices. In one method, determining the presence or amount of N-acetylglyphosate and/or N-acetyl AMPA in a test sample comprises providing the test sample suspected of containing N-acetylglyphosate and/or N-acetyl AMPA; extracting the N-acetylglyphosate and/or N-acetyl AMPA from the test sample; and, detecting the N-acetylglyphosate and/or N-acetyl AMPA in the extract. In other methods, the presence or amount of at least one of glyphosate, N-acetylglyphosate, N-acetyl AMPA or aminomethyl phosphonic acid (AMPA) or a metabolite thereof in a test sample is determined. The method comprises providing the test sample suspected of containing at least one of glyphosate, N-acetylglyphosate, N-acetyl AMPA or AMPA or a metabolite thereof, extracting from the test sample at least one of the glyphosate, N-acetylglyphosate, N-acetyl AMPA or AMPA; and, detecting at least one of the glyphosate, the N-acetylglyphosate, the N-acetyl AMPA and the AMPA from the test sample; wherein detection of the glyphosate, N-acetylglyphosate, N-acetyl AMPA or AMPA occurs without derivatization of the glyphosate, the N-acetylglyphosate, N-acetyl AMPA or the AMPA. | 11-13-2008 |
Anne M. Pianca, Valencia, CA US
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20100152818 | NON-LINEAR ELECTRODE ARRAY - A system for stimulation includes an implantable pulse generator, a lead, and conductors. The lead includes an array body disposed at a distal end of the lead and electrodes concentrically arranged on the array body. A center electrode may also be disposed on the array body. The electrodes may be arranged in more than one concentric ring. A method of using an implantable stimulator includes implanting an implantable stimulator and providing an electrical signal to at least one electrode of the implantable stimulator to stimulate a tissue. The electrical signal may be provided between diametrically opposed electrodes or between electrodes that are not diametrically opposed. If the implantable stimulator has a center electrode, the electrical signal may be provided between the center electrode and at least one concentrically arranged electrode. | 06-17-2010 |
20110118815 | ELECTRODE ARRAY ASSEMBLY AND METHOD OF MAKING SAME - A lead assembly and a method of making a lead are provided. The method of making a multi-contact lead assembly comprises placing monofilament placed in the void spaces not occupied by the plurality of conductor wires and, in one embodiment, thermally fusing the monofilament to the like material spacer by applying heat just below the melting temperature of the monofilament and spacer material. Alternatively, the monofilament and spacer may be of different materials and heat is applied to cause at least one material to thermally reflow or melt. The conductive contacts may be located at either the distal end and/or proximal end of the lead. Oversized spacers may be used in order to provide extra material to fill voids during the thermal fusion/reflow process. | 05-19-2011 |
20110288619 | SYSTEM FOR PERMANENT ELECTRODE PLACEMENT UTILIZING MICROELECTRODE RECORDING METHODS - A lead stimulation/recording system is provided, which is a combination of a permanent DBS stimulating lead and a recording microelectrode. The DBS lead has a lumen extending from the proximal to the distal end of the lead, the lumen having an opening on each end of the lead. The microelectrode is configured and dimensioned to be insertable into the DBS lead from either the distal or proximal opening of the DBS lead, thereby permitting the microelectrode to be placed before, concurrently with, or after placement of the DBS lead. In addition, the system may be used with known microelectrode recording systems and methods of inserting the electrodes, such as the five-at-a-time method, the dual-microdrive method, or the single microdrive method. | 11-24-2011 |
20120271316 | INSERTION TOOL FOR PADDLE-STYLE ELECTRODE - The present disclosure describes various embodiments of an insertion tool that affords steerability of the paddle-style electrode during implantation without causing damage to the insulation and/or the contacts of the paddle-style electrode. One embodiment is described as having a “pin fork” configuration; another a “shovel” configuration; and yet another has tabs or a lumen on the paddle-style electrode for facilitating the insertion of a stylet. The various embodiments for the insertion tool allow for adjustments of the paddle-style electrode in both the medial/lateral and inferior/superior directions allowing the surgeon to steer the paddle-style electrode to the desired stimulation site within the epidural space of the spinal column. | 10-25-2012 |
Anne M. Pianca, Santa Monica, CA US
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20090005823 | LEAD ASSEMBLY FOR IMPLANTABLE MICROSTIMULATOR - A lead assembly for a small implantable medical device (a.k.a, microdevice | 01-01-2009 |
20100076535 | LEADS WITH NON-CIRCULAR-SHAPED DISTAL ENDS FOR BRAIN STIMULATION SYSTEMS AND METHODS OF MAKING AND USING - A lead is configured and arranged for brain stimulation. The lead includes a proximal end and a distal end. The proximal end includes a plurality of terminals disposed at the proximal end. The distal end has a non-circular transverse cross-sectional shape and includes a plurality of electrodes disposed at the distal end. A plurality of conductive wires electrically couple at least one of the plurality of electrodes to at least one of the plurality of terminals. | 03-25-2010 |
20100114278 | DEPOSITED CONDUCTIVE LAYERS FOR LEADS OF IMPLANTABLE ELECTRIC STIMULATION SYSTEMS AND METHODS OF MAKING AND USING - An implantable lead includes an inner core substrate. A plurality of conductors that include at least one layer of at least one conductive material are deposited on the inner core substrate. A patterned insulator layer is disposed over the conductors such that at least two regions of each conductor remain exposed through the insulator. A patterned terminal layer defines a plurality of separated terminals that are deposited at a proximal end of the lead. At least one terminal is electrically coupled to each conductor via at least one of the exposed regions of the at least one conductor. A patterned electrode layer defines a plurality of separated electrodes that are deposited at a distal end of the lead. At least one electrode is electrically coupled to each conductor via at least one of the exposed regions of the at least one conductor. | 05-06-2010 |
20120041497 | LEAD CONNECTOR FOR AN IMPLANTABLE ELECTRIC STIMULATION SYSTEM AND METHODS OF MAKING AND USING - A lead-connection system includes a lead and a connector. The lead includes a distal end, a proximal end, a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductor wires electrically coupling each of the plurality of electrodes to a different one of the plurality of terminals. The connector defines a port for receiving the proximal end of the lead and a plurality of connector contacts. The number of connector contacts is greater than the number of terminals disposed on the proximal end of the lead. When the connector receives the proximal end of the lead, each of the terminals disposed on the proximal end of the lead makes electrical contact with at least one of the connector contacts of the connector and no two terminals make electrical contact with a same one of the connector contacts. | 02-16-2012 |
20130023972 | ELECTRODE ARRAY ASSEMBLY AND METHOD OF MAKING SAME - A lead assembly and a method of making a lead are provided. The method of making a multi-contact lead assembly comprises placing monofilament placed in the void spaces not occupied by the plurality of conductor wires and, in one embodiment, thermally fusing the monofilament to the like material spacer by applying heat just below the melting temperature of the monofilament and spacer material. Alternatively, the monofilament and spacer may be of different materials and heat is applied to cause at least one material to thermally reflow or melt. The conductive contacts may be located at either the distal end and/or proximal end of the lead. Oversized spacers may be used in order to provide extra material to fill voids during the thermal fusion/reflow process. | 01-24-2013 |
20140100586 | INSERTION TOOL FOR PADDLE-STYLE ELECTRODE - The present disclosure describes various embodiments of an insertion tool that affords steerability of the paddle-style electrode during implantation without causing damage to the insulation and/or the contacts of the paddle-style electrode. One embodiment is described as having a “pin fork” configuration; another a “shovel” configuration; and yet another has tabs or a lumen on the paddle-style electrode for facilitating the insertion of a stylet. The various embodiments for the insertion tool allow for adjustments of the paddle-style electrode in both the medial/lateral and inferior/superior directions allowing the surgeon to steer the paddle-style electrode to the desired stimulation site within the epidural space of the spinal column. | 04-10-2014 |
20150151111 | LEADS WITH NON-CIRCULAR-SHAPED DISTAL ENDS FOR BRAIN STIMULATION SYSTEMS AND METHODS OF MAKING AND USING - A lead is configured and arranged for brain stimulation. The lead includes a proximal end and a distal end. The proximal end includes a plurality of terminals disposed at the proximal end. The distal end has a non-circular transverse cross-sectional shape and includes a plurality of electrodes disposed at the distal end. A plurality of conductive wires electrically couple at least one of the plurality of electrodes to at least one of the plurality of terminals. | 06-04-2015 |
Anne M. Rowzee, Rockville, MD US
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20110223604 | Assay for the Measurement of IGF Type 1 Receptor and Insulin Receptor Expression - This invention relates to a quantitative PCR assay that differentiates between IR-A, IR-B and IGF-IR mRNAs and compares expression of the three receptors on the same scale. | 09-15-2011 |
Anne M. Shearrow, Tampa, FL US
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20120128551 | IONIC LIQUID MEDIATED SOL-GEL SORBENTS - Ionic liquid (IL)-mediated sol-gel hybrid organic-inorganic materials present enormous potential for effective use in analytical microextraction. One obstacle to materializing this prospect arises from high viscosity of ILs significantly slowing down sol-gel reactions. A method was developed which provides phosphonium-based, pyridinium-based, and imidazolium-based IL-mediated advanced sol-gel organic-inorganic hybrid materials for capillary microextraction. Scanning electron microscopy results demonstrate that ILs can serve as porogenic agents in sol-gel reactions. IL-mediated sol-gel coatings prepared with silanol-terminated polymers provided up to 28 times higher extractions compared to analogous sol-gel coatings prepared without any IL in the sol solution. This study shows that IL-generated porous morphology alone is not enough to provide effective extraction media: careful choice of the organic polymer and the precursor with close sol-gel reactivity must be made to ensure effective chemical bonding of the organic polymer to the created sol-gel material to be able to provide the desired sorbent characteristics. | 05-24-2012 |
Anne M. Shearrow, Lithia, FL US
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20140057048 | METHOD OF MAKING IONIC LIQUID MEDIATED SOL-GEL SORBENTS - Ionic liquid (IL)-mediated sol-gel hybrid organic-inorganic materials present enormous potential for effective use in analytical microextraction. One obstacle to materializing this prospect arises from high viscosity of ILs significantly slowing down sol-gel reactions. A method was developed which provides phosphonium-based, pyridinium-based, and imidazolium-based IL-mediated advanced sol-gel organic-inorganic hybrid materials for capillary microextraction. Scanning electron microscopy results demonstrate that ILs can serve as porogenic agents in sol-gel reactions. IL-mediated sol-gel coatings prepared with silanol-terminated polymers provided up to 28 times higher extractions compared to analogous sol-gel coatings prepared without any IL in the sol solution. This study shows that IL-generated porous morphology alone is not enough to provide effective extraction media: careful choice of the organic polymer and the precursor with close sol-gel reactivity must be made to ensure effective chemical bonding of the organic polymer to the created sol-gel material to be able to provide the desired sorbent characteristics. | 02-27-2014 |
Anne M. Shelchuk, Cupertino, CA US
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20080287818 | PRESSURE MEASUREMENT-BASED ISCHEMIA DETECTION - In some aspects ischemia is indicated based on cardiac pressure measurements. For example, ischemia may be indicated based on an increase in an intraventricular electromechanical delay where mechanical contractions are detected by measuring pressure in a cardiac chamber. Ischemia detection also may involve obtaining timing information relating to a mechanical contraction of at least one ventricle to identify an intraventricular dyssynchrony. In this case, pressure measurements may be used to identify the timing of the mechanical contraction. Ischemia may be indicated based on a change in a time interval associated with a systolic interval of a ventricle. Ischemia also may be indicated based on an intracardiac electrogram-based indication of ischemia in conjunction with an increase in mean left atrial pressure and/or an increase in the size of a v-wave. | 11-20-2008 |
20110046492 | MONITORING FOR MITRAL VALVE REGURGITATION - Implantable systems, and methods for use therein, for monitoring for mitral valve regurgitation (MR) are provided. An electrogram (EGM) signal and a corresponding pressure signal are obtained, where the EGM signal is representative of electrical functioning of the patient's heart during a plurality of cardiac cycles, and the corresponding pressure signal is representative of pressure within the left atrium the patient's heart during the cardiac cycles. Windows of the pressure signal are defined, based on events detected in the EGM signal, and measurements from the windows are used to monitor for MR. | 02-24-2011 |
20120065532 | Implantable Medical Devices Employing Electroactive Polymers For Sensing Cardiac Motion and/or Causing Cardiac Compression - Disclosed herein is a system for monitoring a motion of a cardiac tissue. The system includes a motion sensor configured to operably couple to the cardiac tissue. The motion sensor includes an electroactive polymer and is further configured to result in a deflection in the electroactive polymer when the cardiac tissue undergoes the motion. The deflection in the electroactive polymer generates an electrical event. | 03-15-2012 |
20120209345 | SYSTEMS AND METHODS FOR REDUCING OCCURRENCES OF ATRIAL ARRHYTHMIAS - A method for reducing occurrences of atrial arrhythmias includes obtaining measures indicative of atrial pressure of a patient, and monitoring for a change in the measures indicative of atrial pressure that is indicative of an increased vulnerability to an atrial arrhythmia. In response to detecting the change in the measures indicative of atrial pressure that is indicative of the increased vulnerability to an atrial arrhythmia, pacing therapy that is adapted to reduce atrial pressure and thereby reduce vulnerability to an atrial arrhythmia is selectively delivered. Additionally, or alternatively, pacing therapy is adjusted to reduce atrial pressure and thereby reduce vulnerability to an atrial arrhythmia. | 08-16-2012 |
Anne M. Shough, New Castle, DE US
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20130143782 | LUBRICANTS WITH IMPROVED LOW-TEMPERATURE FUEL ECONOMY - Lubricating oil compositions, formulated to a preselected viscosity grade that demonstrate stay-in-grade capability in a diesel injector shear stability test, are provided. The compositions comprise a major amount of a base oil of lubricating viscosity and a minor amount of (i) a viscosity modifier (VM) or mixtures thereof having a low shear stability index (SSI) and (ii) a VM or mixtures thereof having an SSI greater than that of the VM from (i). | 06-06-2013 |
20140038864 | METHOD FOR IMPROVING NITRILE SEAL COMPATIBILITY WITH LUBRICATING OILS - Provided are a lubricating engine oil and a method of improving nitrile seal compatibility with a lubricating oil in an engine lubricated with such lubricating oil. The method includes using as the lubricating oil a formulated oil comprising a lubricating oil base stock as a major component and one or more additives selected from the group consisting of (i) a sulfone, sulfolane, or derivative thereof; (ii) a borate ester, boron amide, or mixtures thereof; (iii) a sulfurized olefin; (iv) a thiadiazole or derivative thereof; and (v) a succinic anhydride or derivative thereof, as a minor component. Nitrile seal compatibility is improved as compared to nitrile seal compatibility achieved using a lubricating oil containing a minor component other than the one or more additives. | 02-06-2014 |
20140038872 | METHOD FOR IMPROVING NITRILE SEAL COMPATIBILITY WITH LUBRICATING OILS - Provided is a method of improving nitrile seal compatibility with a lubricating oil in an engine lubricated with the lubricating oil. The method includes using as the lubricating oil a formulated oil comprising a lubricating oil base stock as a major component and an alkylated aromatic base stock as a minor component. Nitrile seal compatibility is improved as compared to nitrile seal compatibility achieved using a lubricating oil containing a minor component other than the alkylated aromatic base stock, e.g., an ester. A lubricating engine oil comprising a lubricating oil base stock as a major component and an alkylated aromatic base stock as a minor component. The alkylated aromatic base stock is present in an amount sufficient for the lubricating oil to exhibit improved nitrile seal compatibility as compared to nitrile seal compatibility achieved using a lubricating oil containing a minor component other than the alkylated aromatic base stock. | 02-06-2014 |
Anne M. Sullivan, Redondo Beach, CA US
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20150346078 | APPARATUS AND METHOD FOR ASSISTING WITH FLUID PRESSURE MEASUREMENT - An apparatus for assisting with measurement of a fluid pressure includes a cover layer having a leading cover edge and upper and lower cover surfaces. A cover aperture fluidly connects the upper and lower cover surfaces. A spacer layer has oppositely facing upper and lower spacer surfaces. A cavity has an upper cavity surface, defined by the lower cover surface, which includes the leading cover edge and the cover aperture. A measuring tube is located adjacent to the upper cover surface. The measuring tube includes a tube lumen. When the lower spacer surface is connected to the substrate, the substrate defines a lower cavity surface and extant fluid is present within the cavity. Variable fluid flowing toward the cavity exerts pressure on the extant fluid to generate an extant fluid pressure level which is physically transmitted through the apparatus and made available for measurement as an extant fluid pressure level. | 12-03-2015 |
Anne M. Sutorius, Las Vegas, NV US
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20120302998 | SKIN TREATMENT METHOD - River rocks are used in a therapy regime whereby the river rocks are used to absorb excess oils from the skin of a user. In one method, river rocks are collected from a source (e.g., river or supplier), sorted for size and color, engraved with logo or other content, packaged and shipped to customers or retailers with instructions on use. Use comprises placement of the river rocks on oily portions of the user's skin for an appropriate time period allowing the river rock to absorb the excess oils. The river rocks are reusable after being washed with mild soap and water. | 11-29-2012 |
Anne M. Taylor, San Marino, CA US
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20080257735 | Microfluidic Device for Enabling the Controlled Growth of Cells and Methods Relating to Same - A multi-compartment microfluidic device for enabling fluidic isolation among interconnected compartments and accomplishing centrifugal positioning and/or patterned substrate positioning of biological specimens. Includes micropatterned substrate coupled with optically transparent housing allowing imaging. Housing includes microfluidic region having entry reservoir for accepting first volume of fluid and additional microfluidic region(s) having a second entry reservoir for accepting second volume of fluid less than first volume of fluid to create hydrostatic pressure. A barrier region that couples the microfluidic region with the second microfluidic region enables biological specimen(s) to extend across the microfluidic, barrier region and second microfluidic region. The barrier region includes embedded microgroove(s) having width and height enabling second volume of fluid to be fluidically isolated from first volume of fluid via hydrostatic pressure maintained via the embedded microgroove(s). Cells are aligned to a chosen location using a centrifuge or patterned substrate techniques. | 10-23-2008 |