Patent application number | Description | Published |
20090011982 | Flagellin Related Polypeptides and Uses Thereof - The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described. | 01-08-2009 |
20090099191 | INHIBITION OF NF-KB - The present invention is generally related to the modulation of cell growth or apoptosis. Compositions for modulating cell growth or apoptosis, methods of use thereof, and methods of identification thereof are described. | 04-16-2009 |
20090246303 | Method for Reducing The Effects of Chemotherapy Using Flagellin Related Polypeptides - The use of flagellin and flagellin related polypeptides for reducing cancer treatment side effects in mammals is described. | 10-01-2009 |
20100112012 | MODULATION OF IMMUNE RESPONSES - Compositions and methods for modulating an NF- | 05-06-2010 |
20110319344 | FLAGELLIN RELATED POLYPEPTIDES AND USES THEREOF - The use of flagellin and flagellin related polypectides for the protection of mammals from the effects of apoptsis is described. | 12-29-2011 |
20110319595 | FLAGELLIN RELATED POLYPEPTIDES AND USES THEREOF - The use of flagellin and flagellin related polypectides for the protection of mammals from the effects of apoptsis is described. | 12-29-2011 |
20120208871 | USE OF TOLL-LIKE RECEPTOR AND AGONIST FOR TREATING CANCER - The present invention is directed to methods and agents used for treating cancer or infectious diseases by providing toll-like receptors such as toll-like receptor 5 (TLR-5) in combination with providing a toll-like receptor agonists such as flagellin resulting in a cis and intrans effect that recruits cells involved in both the innate (cis effect) and adaptive (trans effect) immune response to specifically kill cancer cells and cells infected with a pathogen via the NF-κB apoptosis pathway. | 08-16-2012 |
20120283269 | Method and Compositions for Suppression of Aging - The present invention provides a method of suppression and/or deceleration of mammalian cellular aging. The method involves contacting mammalian cells with a composition that contains a non-genotoxic inducer of p53 (NGIP). In certain embodiments, the NCIP is a Mdm-binding agent or Mdm-2 antagonist. The NGIP can be nutlin, nutlin-3A, a nutlin analog, or a combination thereof. The invention also provides a method for reducing cellular hypertrophy in an organism by administering a composition that contains an anti-hypertrophic compound, such as nutlin, nutlin-3A, a nutlin analog, rapamycin or a rapamycin analog and combinations thereof, to the organism. | 11-08-2012 |
20130004515 | METHODS FOR TREATING REPERFUSION INJURIES - The present invention relates to treating a tissue in a mammal from the effects of reperfusion using flagellin | 01-03-2013 |
20130324462 | Method of Reducing The Effects of Chemotherapy Using Flagellin Related Polypeptides - The use of flagellin and flagellin related polypeptides for reducing cancer treatment side effects in mammals is described. | 12-05-2013 |
20140294900 | FLAGELLIN RELATED POLYPEPTIDES AND USES THEREOF - The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptsis is described. | 10-02-2014 |