Alexander, NC
Christopher Shane Alexander, Albemarle, NC US
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20150099123 | CARBON BASED COATINGS AND METHODS OF PRODUCING THE SAME - Provided herein is a carbon based coating and methods of producing the same. The carbon based coating comprising an amorphous carbon thin film deposited on a substrate, the carbon based coating characterized in that the carbon based coating imparts enhanced surface durability properties. | 04-09-2015 |
Daniel R. Alexander, Matthews, NC US
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20140079980 | THIN BATTERY SEPARATORS AND METHODS - In accordance with at least selected aspects, objects or embodiments, optimized, novel or improved membranes, battery separators, batteries, and/or systems and/or related methods of manufacture, use and/or optimization are provided. In accordance with at least selected embodiments, the present invention is related to novel or improved battery separators that prevent dendrite growth, prevent internal shorts due to dendrite growth, or both, batteries incorporating such separators, systems incorporating such batteries, and/or related methods of manufacture, use and/or optimization thereof. In accordance with at least certain embodiments, the present invention is related to novel or improved ultra thin or super thin membranes or battery separators, and/or lithium primary batteries, cells or packs incorporating such separators, and/or systems incorporating such batteries, cells or packs. In accordance with at least particular certain embodiments, the present invention is related to shutdown membranes or battery separators, and/or lithium primary batteries, cells or packs incorporating such separators, and/or systems incorporating such batteries, cells or packs. | 03-20-2014 |
Danny Alexander, Cary, NC US
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20090155826 | Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same - Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. | 06-18-2009 |
20120003158 | Biomarkers for Inflammatory Bowel Disease and Methods Using the Same - The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of inflammatory bowel disease, methods for distinguishing between inflammatory bowel diseases, methods of determining predisposition to inflammatory bowel disease, methods of monitoring progression/regression of inflammatory bowel disease, methods of assessing efficacy of compositions for treating inflammatory bowel disease, methods of screening compositions for activity in modulating biomarkers of inflammatory bowel disease, methods of treating inflammatory bowel disease, as well as other methods based on biomarkers of inflammatory bowel disease. | 01-05-2012 |
20120122981 | Biomarkers Related to Insulin Resistance and Methods using the Same - Biomarkers relating to glucose disposal rate, insulin resistance, and/or insulin resistance-related disorders are provided. Methods based on the same biomarkers are also provided. | 05-17-2012 |
20120208215 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same - Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. | 08-16-2012 |
20130338031 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same - Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. | 12-19-2013 |
Danny C. Alexander, Cary, NC US
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20090093971 | System and Method for Analyzing Metabolomic Data - The present invention generates a visual display of metabolomic data compiled by a database and associated processor. More particularly, the present invention provides a database for automatically receiving a three-dimensional spectrometry data set for a group of samples. The present invention also provides a processor device for manipulating the data sets to produce plots that are directly comparable to a plurality of characteristic plots corresponding to a plurality of selected metabolites. Furthermore, the processor device may generate a visual display indicating the presence of the selected metabolites across the group of samples. Thus, the present invention enables a user to analyze a series of complex data sets in a visual display that may indicate the presence of the selected metabolites across the group of samples. Furthermore, the visual display generated by embodiments of the present invention also expedites the subjective analysis of the spectrometry data sets. | 04-09-2009 |
20110307180 | SYSTEM AND METHOD FOR ANALYZING METABOLOMIC DATA - The present invention generates a visual display of metabolomic data compiled by a database and associated processor. More particularly, the present invention provides a database for automatically receiving a three-dimensional spectrometry data set for a group of samples. The present invention also provides a processor device for manipulating the data sets to produce plots that are directly comparable to a plurality of characteristic plots corresponding to a plurality of selected metabolites. Furthermore, the processor device may generate a visual display indicating the presence of the selected metabolites across the group of samples. Thus, the present invention enables a user to analyze a series of complex data sets in a visual display that may indicate the presence of the selected metabolites across the group of samples. Furthermore, the visual display generated by embodiments of the present invention also expedites the subjective analysis of the spectrometry data sets. | 12-15-2011 |
Danny Carroll Alexander, Cary, NC US
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20130115649 | Methods and Reagents for Metabolomics and Histology in a Biological Sample and a Kit for the Same - A method of extracting and measuring one or more biochemicals from a biological sample, comprises immersing the biological sample in an organic solvent, whereby one or more biochemicals present in the biological sample are extracted into the organic solvent; separating the biological sample from the free organic solvent; and measuring the level(s) of the one or more biochemicals extracted into the organic solvent, wherein the biological sample remains analyzable by histological analysis. | 05-09-2013 |
Geoffrey D. Alexander, Chapel Hill, NC US
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20090030706 | Method and System for Enhanced Cross-Team Change Request Management - In a data processing system having multiple logically coupled branch systems that share interdependent products and services, a system for providing enhanced cross-team change request management. In one embodiment, the system includes a consumer branch system that generates a consumer change request. A trunk system manages cross-team change requests between the branch systems in a shared database and stores a first cross-team change request that associates the consumer change request with a first provider branch system. In response to the first provider branch system determining that a supplemental consumer change request is required to address the first consumer change request, the first provider branch system generates a second cross-team change request within the trunk system. The second cross-team change request associates the supplemental consumer change request with a second provider branch system. | 01-29-2009 |
George Alexander, Durham, NC US
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20090115484 | DIGITALLY CONTROLLED DELAY ELEMENT - Techniques and corresponding circuits for achieving programmable delay with linear resolution are provided. The techniques provide for incremental delay with substantially equal increments. Linear resolution may be achieved through the use of a circuit arrangement that allows current to be controlled to linearly vary effective resistance of a delay circuit, without affecting the effective capacitance. | 05-07-2009 |
20100030934 | Bus Termination System and Method - A memory system includes a number of integrated circuit chips coupled to a bus. Each of the integrated circuit chips has an input/output node coupled to the bus, the input/output node having a programmable on-die termination resistor. The input/output node of one of the integrated circuit chips is accessed via the bus. The programmable on-die termination resistor of each of the integrated circuit chips is independently set to a termination resistance. The termination resistance is determined by a transaction type and which of the plurality memory devices is being accessed, which information can be transmitted over a separate transmission control bus. | 02-04-2010 |
George William Alexander, Durham, NC US
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20100032820 | Stacked Memory Module - Memory modules, computing systems, and methods of manufacturing memory modules are disclosed. In one embodiment, a memory module includes a substrate having a first side and a second side opposed to the first side. A plurality of pins is disposed on the first side of the substrate. A first plurality of memory chips are arranged in a first chip layer, the first chip layer overlying the second side of the substrate. Electrical contacts of the first plurality of memory chips are electrically coupled to the pins. A second plurality of memory chips is arranged in a second chip layer, the second chip layer overlying the first chip layer. Electrical contacts of the second plurality of memory chips are electrically coupled to the pins. | 02-11-2010 |
20100046266 | High Speed Memory Architecture - Memory devices and memory modules are disclosed. In one embodiment, a memory device includes a semiconductor substrate having a first edge and a second edge opposed to the first edge. A plurality of memory banks is disposed at a central portion of the semiconductor substrate, each memory bank including a plurality of memory cells. A plurality of input/output contacts is disposed between the first edge and the memory banks. Delay locked loop circuitry is disposed adjacent the first edge. A plurality of address and command contacts is disposed between the second edge and the memory banks. | 02-25-2010 |
20100062621 | Horizontal Dual In-line Memory Modules - Horizontal dual in-line memory modules are disclosed. In one embodiment, the memory module includes a circuit board, a plurality of memory chips attached to a top surface of the circuit board, and a plurality of connector contacts disposed under a back surface of the circuit board and extending away from the memory chips, the connector contacts being electrically coupled to the memory chips, the back surface opposite the top surface of the circuit board. | 03-11-2010 |
20100082871 | Distributed Command and Address Bus Architecture - Distributed command and address bus architecture for memory modules and circuit boards is described. In one embodiment, a memory module includes a plurality of connector pins disposed on an edge of a circuit board, the plurality of connector pins comprising first pins coupled to a plurality of data bus lines, second pins coupled to a plurality of command and address bus lines, wherein the second pins are disposed in a first and a second region, wherein a portion of the first pins is disposed between the first and the second regions. | 04-01-2010 |
John Alexander, Pinehurst, NC US
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20140243894 | Devices and Methods for Percutaneous Tricuspid Valve Repair - The present teachings provide devices and methods of treating a tricuspid valve regurgitation. Specifically, one aspect of the present teachings provides devices and methods of identifying a suitable location on the tricuspid annulus, another aspect of the present teachings provides devices and methods of placing a wire across the tricuspid annulus at such an identified location, another aspect of the present teachings provides devices and methods of deploying a tissue anchor across such an identified location, and yet another aspect of the present teachings provides devices and methods of applying tension to two or more of such tissue anchors and reducing the circumference of the tricuspid annulus. As a result, a regurgitation jet is reduced or eliminated. | 08-28-2014 |
20150066138 | Devices and Methods for Locating and Implanting Tissue Anchors at Mitral Valve Commissure - The present teachings provide devices and methods of locating a mitral valve commissure, and implanting tissue anchors at or near the mitral valve commissure. Specifically, one aspect of the present teachings provides devices and methods for locating a mitral valve commissure percutaneously and allowing a guide wire to be placed across a mitral annulus at the mitral valve commissure. Another aspect of the present teachings provides methods for deploying a tissue anchor across a mitral annulus at a mitral valve commissure, including near the P1 or P3 regions of the posterior mitral annulus. Another aspect of the present teachings further provides methods of plicating a mitral annulus between two or more tissue anchors. | 03-05-2015 |
Matthew R. Alexander, Raleigh, NC US
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20150244538 | ENHANCING COLLABORATION IN REAL-TIME GROUP CHAT SYSTEM AND METHOD - A method, computer program product, and computer system for maintaining, between a plurality of participating computing devices, a collaboration session that includes a group instant messaging session within an object, wherein the plurality of participating computing devices includes a host computing device and one or more non-host computing devices in the group instant messaging session. A first sub-object of a plurality of sub-objects is generated within the object, wherein the first sub-object is rendered on the host computing device and the one or more non-host computing devices. Permission is assigned to the host computing device to edit content in the first sub-object, wherein the content in the first sub-object is rendered on the host computing device and the one or more non-host computing devices, and wherein the non-host computing devices are precluded from editing the content in the first sub-object. | 08-27-2015 |
20150244748 | ENHANCING COLLABORATION IN REAL-TIME GROUP CHAT SYSTEM AND METHOD - A method, computer program product, and computer system for maintaining, between a plurality of participating computing devices, a collaboration session that includes a group instant messaging session within an object, wherein the plurality of participating computing devices includes a host computing device and one or more non-host computing devices in the group instant messaging session. A first sub-object of a plurality of sub-objects is generated within the object, wherein the first sub-object is rendered on the host computing device and the one or more non-host computing devices. Permission is assigned to the host computing device to edit content in the first sub-object, wherein the content in the first sub-object is rendered on the host computing device and the one or more non-host computing devices, and wherein the non-host computing devices are precluded from editing the content in the first sub-object. | 08-27-2015 |
Melanie Lynn Alexander, Davidson, NC US
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20100332243 | Goal Insurance - Goal insurance is provided as a purchasable option to users who wish to have a goal tracking system monitor and enforce their goals. The user may define the goal, a reward to be given upon successful completion of the goal and penalties to be applied if the goal is not met. To avoid penalties, the user may purchase goal insurance that may be used or apply under specified circumstances. Such circumstances may include death, illness, unemployment or the like. Goal information and progress may be monitored by the goal tracking system and may further be published to one or more sites. Other users may contribute to the user's reward or send encouraging remarks. If the user does not purchase goal insurance, the predefined penalties may be applied upon expiration of a goal time period if the user has not achieved their goal. | 12-30-2010 |
Paul Alexander, Sanford, NC US
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20090060152 | System and Method for Controlling a Digital Video Recorder on a Cable Network - A system and method for controlling a digital video recorder on a cable network. Signaling associated with the answering or initiation of a digital telephone call by a digital telephone subscriber is used to issue commands to a digital video recorder (DVR). A signal is generated by an MTA when the telephone is enters an “off-hook” state and sent to the DVR to initiate recording of a program being viewed by the called party. When the phone goes “on-hook”, the called party resumes watching the program from exactly where it was interrupted. The MTA may be connected directly to the VTD/DVR and the telephone state is determined by the DVR from information provided by the MTA. Alternatively, a soft switch monitors signaling from the MTA indicative of the state of the called telephone. A telephone state message comprising the telephone state information is then sent over an out-of-band channel/path to a DVR client within the VTD. The DVR client uses the telephone state information to control a DVR. | 03-05-2009 |
Philip T. Alexander, Matthews, NC US
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20130259729 | GEAR PUMP WITH ASYMMETRICAL DUAL BEARING - An asymmetrical bearing is disclosed for use in a gear pump. The bearing may have first and second opposing faces, and first and second bores in communication with the first and second opposing faces. The first and second bores may be configured to receive first and second shafts of a gear pump. The bearing may have a first flat side surface and a second curved side surface, where the second curved side surface includes first and second curved portions associated with the first and second bores, respectively. The first and second faces and the first flat side surface may also include a plurality of grooves configured to direct a flow of process fluid over the bearing during operation of the pump. Self-aligning features can be provided on one or more sealing elements to ensure desired alignment of the sealing components during assembly. Other embodiments are described and claimed. | 10-03-2013 |
Philip Taylor Alexander, Matthews, NC US
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20140255235 | SELF ADJUSTING GEAR PUMP - A self-adjusting gear pump is disclosed. The pump may be a crescent internal gear pump, a gerotor pump, or an external gear pump. The pump includes a pump housing, gear housing, first and second gears, a side plate housing with a side plate, a shim and an end plate. The side plate moves between a first position contacting the first and second gears and gear housing, and a second position contacting the end plate. The side plate is spring biased toward the first position. A method is disclosed for match grinding the crescent plate (if used), gear housing and gears as a unit to provide a uniform surface. The side plate housing and side plate are similarly match ground. An assembly method is disclosed which allows the crescent plate to be moved with respect to the gear housing so that clearances between the crescent and the gear teeth are eliminated. | 09-11-2014 |
Randall W. Alexander, Morrisville, NC US
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20100106780 | Software Architecture for Managing a System of Heterogenous Network Processors and for Developing Portable Network Processor Applications - A method and system for developing portable network processor applications and/or managing heterogeneous network processors in a network is disclosed. The network includes host processor(s) utilizing system configuration application(s) that are network processor independent. In one aspect, the method and system include using standardized interface(s) for each network processor, using a standardized transport layer compatible with the interface(s), and providing a generic message application layer. The generic message application layer defines generic payload(s) and message type(s) for configuration communications between the network and host processors. In another aspect, the method and system include providing packet processing shell(s) and generic protocol software that is coupled with the packet processing shell(s) through standard interface(s), network processor independent, and performs operations for packet processing. The method and system also include providing a library that includes network processor specific information for performing the operations and providing block(s) for performing other network processor specific operations. | 04-29-2010 |
Tony Alexander, Charlotte, NC US
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20080243225 | Stent Removal And Repositioning Device And Associated Method - A stent removal device for removing or repositioning a stent from within a lumen is provided. The stent typically comprises at least one element arranged circumferentially about the stent. The stent removal device includes a tube positioned within the lumen proximate to the stent, wherein the tube is capable of receiving at least a portion of the stent. The stent removal device also includes a pusher positioned within the tube capable of engaging the stent and/or the element. The stent removal device further includes a hook positioned within the tube and including a hook member capable of engaging the element such that force applied to the hook causes the stent to purse string. | 10-02-2008 |
Tony D. Alexander, Charlotte, NC US
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20100305390 | THERAPEUTIC MEDICAL APPLIANCE DELIVERY AND METHOD OF USE - The present invention, in an exemplary embodiment, provides a therapeutic medical appliance, delivery device and method of use. In particular, plug therapeutic medical appliances are provided that allow for the interventional treatment of pulmonary disorders such as defects characterized by pulmonary blebs and/or diffused destructive parenchymal disease. The plug therapeutic medical appliances themselves combine many of the excellent characteristics of both silicone and metal therapeutic medical appliances while eliminating the undesirable ones. In particular, these therapeutic medical appliances are preferably self-expanding in nature and allow the predetermined differential selection of relative hardness/softness of regions of the therapeutic medical appliance to provide additional patient comfort. An exemplary embodiment also provides a family of delivery devices that facilitate flexibility, durability and/or proper installation of one or more medical appliances in a single procedure. Moreover, the preferred embodiment of the delivery device provides for the reloading of the delivery device with additional medical appliances for additional interventional procedures. | 12-02-2010 |
20110082392 | LUMEN-MEASURING DEVICES AND METHOD - The present invention provides a lumen measuring device and method that allows the user to calculate the exact length and diameter of a suitable interventional prosthesis as well as the height and length of stenosis during the same exploratory procedure. | 04-07-2011 |