Patent application number | Description | Published |
20080286827 | BIOMARKERS - The invention relates to biomarkers for use in diagnosing cancer and in classifying tumors. | 11-20-2008 |
20090029362 | GENE COPY NUMBER PROFILING - The invention relates to copy number profile analysis. Specifically, copy number profile analysis is used to determine whether two or more separate tumors in a single individual are derived from a common source. | 01-29-2009 |
20120015050 | METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY - This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided. | 01-19-2012 |
20120041274 | CANCER BIOMARKERS - Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided. | 02-16-2012 |
20130005592 | METHODS AND COMPOSITIONS FOR PREDICTING CANCER THERAPY RESPONSE - The invention generally relates to molecular diagnostics, and particularly to molecular markers for cancer therapy response and methods of use thereof. | 01-03-2013 |
20130058924 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided. | 03-07-2013 |
20130079423 | DIAGNOSTIC METHODS INVOLVING LOSS OF HETEROZYGOSITY - The invention relates generally to methods of molecular analysis and particularly to methods of using genetic copy number variations and loss of heterozygosity in the characterization and treatment of disease. | 03-28-2013 |
20130143747 | METHODS OF DETECTING CANCER - Methods and compositions involving molecular markers for the detection and characterization of cancer in a patient are provided. | 06-06-2013 |
20130302242 | GENE SIGNATURES FOR CANCER DIAGNOSIS AND PROGNOSIS - Biomarkers and methods using the biomarkers for molecular detection and classification of disease and, particularly, molecular markers for cancer diagnosis and prognosis and methods of use thereof are provided. | 11-14-2013 |
20140134166 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided. | 05-15-2014 |
20140162886 | METHODS AND MATERIALS FOR ASSESSING ALLELIC IMBALANCE - Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided. | 06-12-2014 |
20140170139 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided. | 06-19-2014 |
20140170242 | GENE SIGNATURES FOR LUNG CANCER PROGNOSIS AND THERAPY SELECTION - The invention provides for molecular classification of disease and, particularly, molecular markers for lung cancer prognosis and therapy selection and methods and systems of use thereof. | 06-19-2014 |
20140212415 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular classification of disease are provided. | 07-31-2014 |
20140271546 | GENES AND GENE SIGNATURES FOR DIAGNOSIS AND TREATMENT OF MELANOMA - Panels of biomarkers, methods and systems are disclosed for determining gene expression, and diagnosing and treating melanoma. | 09-18-2014 |
20140278135 | ELECTRONIC VARIANT CLASSIFICATION - A computer-implemented method is discussed that includes identifying, by a computer server system, stored electronic data that represents genetic sequencing for one or more genes for individuals in a population of patients who have submitted to genetic sequencing; generating, for each of multiple individuals and from the stored electronic data, probability data for the individuals and probability or weighting data, or both, for relatives of the individuals, the probability data representing likelihoods that a particular person corresponding to the probability data carries a deleterious mutation in a particular gene; and generating a score for a genetic variant, wherein the score is a function of probability or weighting data, or both, for the individuals and for relatives of the individuals, and the score represent a composite probability that a certain variant is a deleterious or benign variant. | 09-18-2014 |
20140303001 | BLADDER CANCER DETECTION AND MONITORING - Provided are molecular markers for detecting bladder cancer, especially recurrent bladder cancer, and methods of use thereof, including methods of monitoring for the recurrence of bladder cancer. | 10-09-2014 |
20140315935 | GENE SIGNATURES FOR LUNG CANCER PROGNOSIS AND THERAPY SELECTION - The invention provides for molecular classification of disease and, particularly, molecular markers for lung cancer prognosis and therapy selection and methods and systems of use thereof. | 10-23-2014 |
20140363521 | METHODS AND MATERIALS FOR ASSESSING HOMOLOGOUS RECOMBINATION DEFICIENCY - This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided. | 12-11-2014 |
20150018527 | METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY - This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided. | 01-15-2015 |
20150080260 | METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY - This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided. | 03-19-2015 |