Patent application number | Description | Published |
20100249914 | Sustained drug-releasing stent - A stent includes a stent body of a cylindrical configuration having outer and inner surfaces, a first coated layer coating at least the outer surface, and a second coated layer coating substantially completely over the first coated layer. The first coated layer is prepared of a first composition comprising a polymer and a vascular intimal hyperplasia inhibitor (preferably argatroban) of a kind, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the inhibitor being within the range of 8:2 to 3:7. On the other hand, the second coated layer is prepared of a polymer alone or a second composition comprising a polymer and a drug, the weight compositional ratio of the drug to 80% by weight of the polymer being less than 20% by weight. | 09-30-2010 |
20120310329 | SUSTAINED DRUG-RELEASING STENT - A stent includes a stent body of a cylindrical configuration having outer and inner surfaces, a first coated layer coating at least the outer surface, and a second coated layer coating substantially completely over the first coated layer. The first coated layer is prepared of a first composition comprising a polymer and a vascular intimal hyperplasia inhibitor (preferably argatroban) of a kind, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the inhibitor being within the range of 8:2 to 3:7. On the other hand, the second coated layer is prepared of a polymer alone or a second composition comprising a polymer and a drug, the weight compositional ratio of the drug to 80% by weight of the polymer being less than 20% by weight. | 12-06-2012 |
20130018455 | METHOD OF INHIBITING VASCULAR INTIMAL HYPERPLASIA USING STENT - A method of inhibiting vascular intimal hyperplasia including: placing a stent within a blood vessel, the stent having a stent body of a cylindrical configuration having outer and inner surfaces with a diamond-like thin film coated on the surfaces, a first coated layer coating at least the outer surface of the stent body, the first coated layer being prepared of a first composition comprising a biodegradable polymer and a vascular intimal hyperplasia inhibitor of a kind, comprising argatroban, which does not inhibit proliferation of endothelial cells, the weight composition ratio of the polymer to the vascular intimal hyperplasia inhibitor being within the range of 8:2 to 7:3, and a second coated layer; and causing argatroban to be released from the stent to thereby inhibit the vascular intimal hyperplasia without inhibiting proliferation of endothelial cells. | 01-17-2013 |
Patent application number | Description | Published |
20090048667 | Controlled Drug-Release Composition and Drug-Releasable Medical Device - A drug-releasable medical device contains a controlled drug-release composition comprising 100 parts by weight of an organic polymeric material which is soluble in an organic solvent and insoluble in water, 5 to 60 parts by weight of a lipid-soluble, low molecular weight release auxiliary agent and 1 to 70 parts by weight of a drug. When the composition is applied on a stent, a catheter, an organ replacement medical device, an artificial organ or the like in the form of coating or the like, the medical device is provided with a drug release function. Argatroban or sarpogrelate hydrochloride or both of them are gradually released from the surface of a stent for treating coronary artery stenosis, for example. In order to exhibit a sustained-release function for a desired period of time, the drug to be gradually released is carried in a polymeric material coated on a surface of a metal forming the stent or in a porous stent substrate. | 02-19-2009 |
20100198344 | SUSTAINED DRUG-RELEASING STENT - A stent includes a stent body of a cylindrical configuration having outer and inner surfaces, a first coated layer coating at least the outer surface, and a second coated layer coating substantially completely over the first coated layer. The first coated layer is prepared of a first composition comprising a polymer and a vascular intimal hyperplasia inhibitor (preferably argatroban) of a kind, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the inhibitor being within the range of 8:2 to 3:7. On the other hand, the second coated layer is prepared of a polymer alone or a second composition comprising a polymer and a drug, the weight compositional ratio of the drug to 80% by weight of the polymer being less than 20% by weight. | 08-05-2010 |
Patent application number | Description | Published |
20080237098 | MAGNETIC SEPARATION FILTERING AND CLEANING APPARATUS - A magnetic separation filtering and cleaning apparatus for adding flocculant and magnetic powder to raw water containing pollutant particles to form magnetic floc in treated fluid and separating and removing the magnetic floc from the treated fluid, comprising: a magnetic field generation device being provided in a rotating body for suctioning the magnetic floc on a surface of the rotating body from the treated fluid containing the magnetic floc, a magnetic field rotating device for rotating the magnetic field generation device, a sludge recovery device for separating sludge including the magnetic floc mechanically from the surface of the rotating body of the magnetic field generation device; and a filtering device having a rotating net for filtering out the magnetic floc from the treated fluid including the magnetic floc and flowing down the treated fluid filtered through the rotating net. | 10-02-2008 |
20080245739 | TREATMENT METHOD OF ORGANIC COMPOUNDS INCLUDED IN WASTE WATER, A TREATMENT APPARATUS OF ORGANIC COMPOUNDS INCLUDED IN WASTE WATER, A TREATMENT SYSTEM OF ORGANIC COMPOUNDS INCLUDED IN WASTE WATER, AND A BITUMEN COLLECTING SYSTEM - A treatment method of organic compounds included in waste water, comprising the steps of: | 10-09-2008 |
20090215161 | MICROORGANISM TESTING DEVICE AND CHIP FOR TESTING MICROORGANISMS - There is disclosed a microorganism testing device in which various types of microorganisms can be easily concentrated. The microorganism testing device includes a detection chip, a carrier device, a controller, and a magnet. The detection chip includes a specimen container for holding a specimen containing microorganisms, a trapping particle liquid container for holding trapping particle liquid containing magnetic particles, a microorganism trapping section for trapping the microorganisms, and a liquid flow path. In a state where a magnetic force of the magnet acts on the microorganism trapping section, the controller controls the carrier device to flow the trapping particle liquid into the microorganism trapping section to form a filtration filter by trapping plural magnetic particles in the microorganism trapping section, and in this state, to flow the microorganisms into the microorganism trapping section so that the microorganisms within the specimen are deposited on one side of the filtration filter. | 08-27-2009 |
20100176039 | TREATMENT METHOD OF ORGANIC COMPOUNDS INCLUDED IN WASTE WATER, A TREATMENT APPARATUS OF ORGANIC COMPOUNDS INCLUDED IN WASTE WATER, A TREATMENT SYSTEM OF ORGANIC COMPOUNDS INCLUDED IN WASTE WATER, AND A BITUMEN COLLECTING SYSTEM - A treatment method of organic compounds included in waste water, comprising the steps of:
| 07-15-2010 |
20120043264 | FLOCCULATION-MAGNETIC SEPARATION SYSTEM - A flocculation-magnetic separation is provided which reduces the usage amount of flocculation agents as well as the usage amount of magnetic powders and realizes an improvement in the quality of treated water. | 02-23-2012 |
Patent application number | Description | Published |
20110168639 | WASTEWATER TREATMENT METHOD AND WASTEWATER TREATMENT APPARATUS - A wastewater treatment method in which magnetic flocs are formed by adding to wastewater an inorganic flocculant, magnetic particles, and a high molecular polymer as a polymeric flocculant, and the magnetic flocs are collected with magnetic force to thereby obtain treated water having the magnetic flocs removed from the wastewater, wherein the improvement comprises that
| 07-14-2011 |
20140367341 | COAGULANT, COAGULATION METHOD, AND WATER TREATMENT APPARATUS - In order to rapidly remove an organic acid dissolved in contaminated water, a coagulant capable of forming a floc with the organic acid in the contaminated water is configured to include an iron oxide bearing an inorganic acid on surface thereof, and an aqueous solution of an acidic-group-containing polymer. Upon removal of the organic acid as a floc from the contaminated water using the coagulant, the iron oxide bearing an inorganic acid on surface is initially added to the contaminated water, and then the aqueous solution of the acidic-group-containing polymer is added to precipitate a floc, and the floc is magnetically separated. A water treatment apparatus enabling removal of an organic substance from contaminated water is provided with a mechanism for stirring the contaminated water, a mechanism for adding an iron oxide bearing an inorganic salt on surface to the contaminated water, a mechanism for adding an aqueous solution of an acidic-group-containing polymer to form a floc, and a mechanism for magnetically separating the formed floc. | 12-18-2014 |