48th week of 2008 patent applcation highlights part 37 |
Patent application number | Title | Published |
20080292675 | Antimicrobial medicotechnical product, process for its production and use - The invention relates to a medicotechnical product having an antimicrobial finish consisting of a complex material of metal nanoparticles and macromolecules, the macromolecules being at least partially formed from amphiphilically modified polyamino acids which contain amino acid units, which aside from the functional groups bonded in the peptide bond contain at least one further functional group and at least some of these groups are modified with substances bearing hydrophobic radicals via covalent bonds. The hydrophobic radicals are bonded by addition of substances bearing epoxy groups to the at least one further functional group and/or via at least one amino group of an amino acid unit bearing at least one amino group as a further functional group with maintenance of an amino function on the polyamino acids. The invention furthermore relates to the production of the complex material and of the medicotechnical product. | 2008-11-27 |
20080292676 | Bioactive acid agrichemical compositions and use thereof - Bioactive agrichemical concentrates and compositions having improved bioactivity comprising metal-acid solutions. | 2008-11-27 |
20080292677 | Engineered lung tissue, hydrogel/somatic lung progenitor cell constructs to support tissue growth, and method for making and using same - Somatic lung progenitor cell/polymer constructs are disclosed along with methods for isolating somatic lung progenitor cells from adult mammals, seeding the cells onto or into polymeric scaffolds and allowing the cells to differentiate and proliferate into functional lung tissue/polymer implants. A method for treating lung disease, disorders or injuries is also disclosed. | 2008-11-27 |
20080292678 | MEDICAL ARTICLES HAVING ENZYMATIC SURFACES FOR LOCALIZED THERAPY - An enzymatically active medical article is provided, which comprises a medical article and an enzyme disposed at or near a surface of the medical article such that the medical article is provided with an enzymatically active surface. The enzyme is selected, for example, from the group consisting of protease enzymes, glycosidase enzymes, enzymes that degrade cholesterol esters, enzymes that convert hydrocortisone to cortisone, enzymes that degrade oxalate, and enzymes that generate NO from arginine. | 2008-11-27 |
20080292679 | BIODEGRADABLE DRUG DELIVERY SYSTEM - A drug delivery system (DDS) comprised of segmented biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The segmented implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer, and permit the DDS to have segments that possess individual and different drug release characteristics. | 2008-11-27 |
20080292680 | Hypercompressed polymer particles for controlled release ophthalmic medications - An ophthalmic dispensing device having a polymer which is combined with an ophthalmic therapeutic agent in the form of a microparticle which is hypercompressed to form a controlled release dispensing device for ophthalmic use. | 2008-11-27 |
20080292681 | Use of Dha, Epa or Dha-Derived Epa for Treating a Pathology Associated with Cellular Oxidative Damage - The present invention relates to the use of an acid enriched in docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) or DHA-derived EPA for manufacturing a drug for the treatment of processes that involve associated oxidative damage. In particular, it is for the treatment of processes associated with neurodegenerative, ocular, ischaemic and inflammatory pathology, atherosclerosis, with oxidative damage to DNA and with physical exercise. | 2008-11-27 |
20080292682 | METHOD FOR TREATING ALLERGIC DERMATITIS - A method for treating oleoresin induced allergic dermatitis by topically contacting an affected area with a therapeutically effective amount of one or more biopolymers for a sufficient amount of time to enable the one or more biopolymers to have an effect and removing the one or more biopolymers from the affected area. The oleoresin can be urushiol, isosolenopsin A, or a combination thereof. The one or more biopolymer can be albumin. The one or more biopolymers can provide a localized anti-inflammatory effect. | 2008-11-27 |
20080292683 | Film shreds and delivery system incorporating same - Compositions are provided that include water soluble or water dispersible film shreds, a carrier and an active, such as, but not limited to a drug, flavoring agent or coloring agent. Also provided are methods of use of the film shreds, such as in improving the dissolution, stability, aesthetics, or taste of a composition or its components, and in reducing a disease risk associated with an active. | 2008-11-27 |
20080292684 | Device for Delivery of Active Principles - A device for the delivery of active principles for dermal and, in particular, transdermal application having the form of a two-layered patch consisting of a first layer having a homogeneous composition and comprising at least one active principle, a water-soluble film-forming agent and a hydrophilic adhesive polymer, and of a second layer joined in a permanent manner to the first and having a water vapour permeability of less than 500 g/m | 2008-11-27 |
20080292685 | Transdermal Patch Containing Isosorbide Dinitrate and Bisoprolol - This invention relates to a transdermal patch in the form of a layer complex, comprising a backing layer, a drug-reservoir layer comprising pharmacologically active ingredients and pharmaceutically acceptable adjuvants, and a release liner covering the drug-reservoir layer, characterized in that the drug-reservoir layer comprises isosorbide dinitrate and Bisoprolol at a ratio of 1:3 to 3:1 by weight, as the pharmacologically active ingredients. Animal tests show that said patch can reduce the elevation of T wave of cardiogram, the increase of the level of myocardial enzyme in blood serum, and the extension of the range of myocardial infarction caused by ligating the coronary artery in animals. Results show that said patch exhibits a considerable synergistic effect in the treatment of cardiovascular diseases and has good preventive and therapeutic effects on several adverse events on heart. In addition, the animal tests show that the patch according to the invention has a better pressure-reducing effect than the application of the patch containing only one of isosorbide dinitrate and Bisoprolol, and does not worsen the arrhythmia that is easily caused by the application of the patch containing only isosorbide dinitrate or Bisoprolol. | 2008-11-27 |
20080292686 | Vaccine - The present invention provides novel intradermal vaccines and novel uses for adjuvants in the preparation of intradermal vaccines, and also novel methods of treatment comprising them. The intradermal adjuvants, and methods, of the present invention comprise a saponin and a sterol, wherein the saponin and sterol are formulated in a liposome. The intradermal adjuvants are used in the manufacture of intradermal vaccines for humans, and in the intradermal treatment of humans. | 2008-11-27 |
20080292687 | Methods of Treating Cancer and Other Conditions or Disease States Using Lfmau and Ldt - The present invention relates to the use of the compound according to formula (I), below for the treatment of tumors, cancer and hyperproliferative diseases, among other conditions or disease states: Where X is H or F; R | 2008-11-27 |
20080292688 | Liposome and preparation method of the same - The present invention relates to a composition and a method for preparing a liposome, the liposome including a lipid bilayer and an aqueous core contains a hydrophobic or a hydrophilic drug and a component—Vitamin E derivative (d-α tocopheryl polyethylene glycol 1000 succinate; TPGS). TPGS is able to increase the encapsulation efficiency of drug in liposome as well as to enhance the stability of drug in liposomes. Such liposome is capable to increase the skin permeation of drugs. The preparation method comprises the following steps: (1) adding the drug to a Vitamin E derivative solution to form a mixture; and (2) adding at least one phosphatidyl choline to the mixture, after hydration from either sonication or homogenization. | 2008-11-27 |
20080292689 | METHOD FOR INHIBITING FREE RADICALS - A method for inhibiting free radical is provided. The method includes administering to a subject an effective amount of an herbal composition including | 2008-11-27 |
20080292690 | MULTI-MEMBRANE IMMUNOISOLATION SYSTEM FOR CELLULAR TRANSPLANT - This invention relates to an immunoisolation encapsulation system that protects cellular transplants and thus allows cell function and survival without the need of immunosuppression. The immunoisolation system is a multi-component, multi-membrane capsule that allows optimization of multiple design parameters independently for reproducible functions in large animals models. | 2008-11-27 |
20080292691 | BARIATRIC MAGNETIC APPARATUS AND METHOD OF MANUFACTURING THEREOF - A bariatric procedure or delivery apparatus is configured in such a way to deter premature passing of magnetic members through the pylorus. In other exemplary embodiments, the magnetic apparatus includes a plurality of magnetic members, having one of a variety of configurations, wherein plural magnetic poles are disposed on a surface of the apparatus. | 2008-11-27 |
20080292692 | Impermeable Capsules - A capsule comprising a core and a shell surrounding and enclosing the core, the shell comprising at least one first polymer having a first water solubility parameter, and at least one second polymer having a water solubility parameter higher than the first water solubility parameter, wherein the second polymer is crosslinked, and/or all of the at least one second polymer is present in an amount that is less than all of the at least one first polymer. Upon exposure to an aqueous medium, the first polymer begins to swell, and water begins to leak into the capsule. Also, the second polymer is attracted to the entering water. As the second polymer absorbs water and swells, the mean free space in the shell decreases and the tortuous pathway for materials crossing the boundary of the wall increases. As a result, leakage rates across the capsule wall decrease. | 2008-11-27 |
20080292693 | COMPOSITION AND METHOD FOR TREATING DIGESTIVE SYSTEM DISORDERS - The present disclosure provides for a novel composition, with active ingredients comprising d-Limonene and Aloe mucilaginous polysaccharides (AMPs), for the treatment of a wide variety of digestive system disorders and diseases, including conditions which affect the stomach, esophagus, bowel, colon, liver or pancreas are considered digestive system diseases and disorders, including, but not limited to, gastro-esophagus reflux disease (GERD), digestive problems such as acid reflux disease, Crohn's disease, colitis, inflammatory bowel disease (IBD), irritable bowel disease (IBS), diverticulitis, gastritis, peptic ulcers and spastic colon. | 2008-11-27 |
20080292695 | CARVEDILOL FORMS, COMPOSITIONS, AND METHODS OF PREPARATION THEREOF - Disclosed are amorphous carvedilol salt forms, controlled-release carvedilol compositions, and methods of preparing the forms and compositions. | 2008-11-27 |
20080292696 | Enteric Sustained-Release Tablet Comprising Paroxetine - The present invention relates to an enteric, sustained-release tablet comprising paroxetine or a hydrates or anhydrides of a pharmaceutically acceptable salt thereof as active substance, more particularly to a tablet prepared by coating a sustained-release tablet core containing paroxetine with an enteric polymer, wherein the interaction between the tablet core and the enteric coating layer is minimized to enable constant drug release without regard to the residence time of the tablet in the stomach. | 2008-11-27 |
20080292697 | Direct compression polymer tablet core - The present invention provides a tablet comprising a compressed tablet core which comprises at least about 80% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 80% by weight of an aliphatic amine polymer resin. The method comprises the step of compressing the aliphatic amine polymer to form the tablet core. The tablet core can further include one or more excipients. In this embodiment, the method of producing the tablet core comprises the steps of: ( | 2008-11-27 |
20080292698 | PHARMACEUTICAL COMPOSITIONS OF ISOLATED ORTHORHOMBIC CRYSTALLINE 4-[6-ACETYL-3-[3-(4-ACETYL-3-HYDROXY-2-PROPYLPHENYLTHIO)PROPOXY]-2-PROPYLPHENOXY]BUTYRIC ACID AND METHODS OF USE - A pharmaceutical composition comprising a compound of formula (1) in polymorphic crystalline Form A: | 2008-11-27 |
20080292699 | SOLID PHARMACEUTICAL DOSAGE UNIT FOR ALLEVIATING SYMPTOMS OF RHINORRHEA - A solid pharmaceutical dosage unit for alleviating the symptoms of rhinorrhea. The dosage unit comprises an anticholinergic agent and an antihistamine and, optionally, a decongestant and, when placed in a basket in 500 ml of 0.01 N HCl of 37° C. which is stirred at 100 rpm, releases at least about 75% of the at least one anticholinergic agent within 45 minutes and releases the at least one antihistamine at a rate of from about 20% to about 60% after 2 hours, from about 45% to about 80% after 4 hours and at least about 75% after 8 hours. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way. | 2008-11-27 |
20080292700 | CONTROLLED RELEASE FORMULATIONS USING INTELLIGENT POLYMERS - A controlled release pharmaceutical composition comprises (a) topiramate or a pharmaceutically acceptable salt thereof, (b) a first intelligent polymer component; and (c) a second intelligent polymer component having opposite wettability characteristics to the first intelligent polymer component. The polymer components are effective for controlled release of the pharmaceutically active substance from the composition. | 2008-11-27 |
20080292701 | Orally disintegrable tablets - An orally disintegrable tablet, of the present invention, which comprises (i) fine granules having an average particle diameter of 400 μm or less, which fine granules comprise a composition coated by an enteric coating layer, said composition having 10 weight % or more of an acid-labile physiologically active substance and (ii) an additive, has superior disintegrability or dissolution in the oral cavity so that it can be used for treatment or prevention of various diseases, as an orally disintegrable tablet capable of being administered to the aged or children and easily administered without water. Also, because the tablet of the present invention contains fine granules having the average particle diameter such that it will not impart roughness in mouth, it can be administered easily without discomfort at the administration. | 2008-11-27 |
20080292702 | Solid Dispersion Comprising An Active Ingredient Having A Low Melting Point And Tablet For Oral Administration Comprising Same - A fused solid dispersion comprising an active ingredient having a melting point of 800 C or below and a pharmaceutically acceptable absorbent having a specific surface area ranging from 20 to 400 mVg can be conveniently compressed into a tablet without generating capping and sticking problems, and a tablet comprising said fused solid dispersion can maintain an uniform release rate over a prolonged time when orally administered. | 2008-11-27 |
20080292703 | Antitumoral Bioconjugates of Hyaluronic Acid or Its Derivatives Obtained by Indirect Chemical Conjugation, and Their Use in the Pharmaceutical Field - The present invention describes a new group of bioconjugates which can be obtained by means of indirect synthesis, via a molecular spacer, between hyaluronic acid and/or its derivatives and drugs with an antitumoral activity belonging to different groups, their preparation process and use in the oncological field. The new derivatives, in relation to the type of bond and Substitution degree, have different physico-chemical properties which improve their tolerability and efficiency and allow a more accurate modulation of the dosage, exploiting an active targeting mechanism. | 2008-11-27 |
20080292704 | Methods and Compositions Involving Polymeric Immunoglobulin Fusion Proteins - The present invention concerns inventive polypeptides. The present invention also concerns compositions and vaccines comprising the inventive polypeptides. In other embodiments of the invention, the inventive polypeptides are provided to a subject, used to vaccinate, or used to induce immunity. Other embodiments include methods for making the inventive polypeptides and nucleic acids used to encode the inventive polypeptides. | 2008-11-27 |
20080292705 | Emulsifier system - The invention relates to an emulsifier system, which comprises a nanoparticle with a positive or negative net charge and a hydrophobic compound of opposite charge to the nanoparticle that will bind to the nanoparticle making it hydrophobic and the use of that system for preparing water-in-oil (WIO) emulsions as well as oil-in-water (O/W) emulsions. | 2008-11-27 |
20080292706 | Hydrogel composition and methods for making the same - The invention provides a hydrogel composition comprising water and a hydrophilic polymer, wherein the hydrogel composition has (a) an ultimate tensile strength of about 10 kPa or more, (b) a compressive strength of about 70 kPa or more, or (c) an ultimate tensile strength of about 10 kPa or more and a compressive strength of about 70 kPa or more. The invention further provides methods for producing a hydrogel composition. | 2008-11-27 |
20080292707 | Pharmaceutical Compositions of Adsorbates of Amorphous Drug - Pharmaceutical compositions comprise a low-solubility drug adsorbed onto a high surface area substrate to form an adsorbate. The compositions in some embodiments include a concentration-enhancing polymer. | 2008-11-27 |
20080292708 | Polymeric Adhesive Matrix with Salified Carboxylic Groups for Transdermal Use - Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0° C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix. | 2008-11-27 |
20080292709 | KITS FOR DHEA AND DHEA-SULFATE FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE - Kits for treating or preventing chronic obstructive pulmonary disease (COPD) by using as active agent a non-glucorticoid steroid, analogue thereof, such as dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S), or their salts, in an amount effective for preventing or treating COPD. | 2008-11-27 |
20080292710 | Liquid Dosage Forms Of Acid Labile Drugs - Liquid formulations of acid-labile drugs are provided. The formulations generally comprise micro-granules comprising an acid-labile drug coated with an enteric coating and a liquid vehicle having a pH less than 6.0. The components of the formulation can separately provided in the form of kits. The formulations and kits may be used to treat patients suffering from disorders for which the acid labile drugs are indicated. | 2008-11-27 |
20080292711 | Polysiloxane Coated Metal Oxide Particles - The invention provides novel coated metal oxide particles, wherein metal oxide particles are coated with a sunscreen on a polysiloxane basis with UV-A and/or UV-B and/or UV-C and/or broadband filter activity and a process for producing coated metal oxide particles and their use especially in cosmetic or dermatological formulations for the protection against harmful effects of sunlight. | 2008-11-27 |
20080292712 | METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF BIOACTIVE MOLECULES - Formulations for controlled, prolonged release of bioactive molecules such as therapeutic proteins, peptides and oligonucleotides have been developed. These formulations are based on solid microparticles or nanoparticles formed of the combination of biodegradable, synthetic polymers such as poly (lactic acid) (PLA), poly (glycolic acid) (PGA), and copolymers thereof. Bioactive molecules are coupled to hydrophilic polymers such as polyethylene glycol or polypropylene glycol and formulated to provide controlled release. The bioactive molecules are more stable, less immunogenic and have improved release rate profiles with lower burst levels and increased drug loading relative to the same bioactive molecules lacking coupled hydrophilic polymers. The controlled release formulations can be administered by injection, by inhalation, nasally, or orally. | 2008-11-27 |
20080292713 | Respirable Powders - A spray dried dispersible powdered composition suitable for inhalation by a human subject, which composition comprises: a) at least one active agent suitable for treating a condition in said subject by inhalation; b) a hydrophobic amino acid; and c) a pharmaceutically acceptable biodegradable polymer. | 2008-11-27 |
20080292714 | BONE TARGETING OF DEGRADABLE DRUG FILLED NANOPARTICLES - This invention provides a method of modifying a cellular response in a mammal. The method comprises administering to the mammal an effective amount of biodegradable nanoparticles, each of said nanoparticles comprising an active agent, a biodegradable polymer, and a bone targeting agent administering to a mammal an effective amount of a composition comprising a compound absorbed in a biodegradable nanoparticle which is attached to a bone targeting agent. The invention also provides a method for modifying a cellular response in a mammalian cell comprising contacting the mammalian cell with biodegradable nanoparticles. The invention further provides a method of delivering an exogenous substance to a mammal. The method comprises administering to the mammal a composition comprising the exogenous substance absorbed into a biodegradable nanoparticle, wherein the biodegradable nanoparticle is covalently attached to a bone targeting agent. The invention also provides a composition and a process for preparing the composition comprising a biologically active or therapeutic agent of compound, a biodegradable nanoparticle, and a bone targeting agent. | 2008-11-27 |
20080292715 | Unique Manuka Factor (Umf) Fortified Honey - The invention relates to UMF amended food stuffs and medicaments. In particular, although not exclusively, the invention relates to UMF fortified honey, methods for the preparation of UMF fortified honey, and methods for the preparation of UMF containing fractions of honey. | 2008-11-27 |
20080292716 | Electrolytic Water and Process for Production Thereof - The present invention discloses a process for producing an electrolytic water, wherein a to-be-electrolyzed water containing less than 0.1 mM of a water-soluble inorganic salt, 0.05 to 0.5 mass % of a hydroquinone derivative and 1 to 50 mM of L-ascorbic acid or a derivative thereof is fed into a diaphragm-free electrolytic cell of continuous flow type at a flow rate of 5 to 3,000 l/min and electrolysis is conducted continuously at a current density of 0.003 to 0.1 A/cm | 2008-11-27 |
20080292717 | Highly Stable Aqueous Solution, Electrode with Nanocoating for Preparing the Solution and Method for Making this Electrode - A highly stable aqueous solution having a molecular cluster with dimensions which are small enough to ensure substantial chemical-physical stability thereof for a relatively long time. To prepare the solution a fluid treatment device is used, which comprises at least one chamber ( | 2008-11-27 |
20080292718 | Method for Suppression Appetite and Food Intake - The invention relates to method for suppressing appetite and food intake in a mammal in need thereof comprising a step of administering to said mammal an effective amount of water comprising from 99.76 to 99.99 molecular % of isotopologue | 2008-11-27 |
20080292719 | Method of Treating Metabolic Syndrome - The invention relates to the method of treating metabolic syndrome in a mammal in need thereof comprising a step of administering to said mammal an effective amount of water comprising from 99.76 to 99.99 molecular % of isotopologue | 2008-11-27 |
20080292720 | CHOLESTEROL-INTERACTING LAYERED PHYLLOSILICATES AND METHODS OF REDUCING HYPERCHOLESTEREMIA IN A MAMMAL - Layered phyllosilicates are useful for adsorbing and/or binding to cholesterol and, thereby, reducing blood cholesterol in a patient. Accordingly, provided herein is a method of reducing hypercholesteremia in a mammal comprising administering to said mammal a protonated and at least partially exfoliated layered phyllosilicate material alone and in combination with other cholesterol-reducing agents in an amount effective to reduce hypercholesteremia in said mammal. | 2008-11-27 |
20080292721 | Bioactive acid agrichemical compositrions and use thereof - Bioactive agrichemical concentrates and compositions having improved bioactivity comprising metal-acid solutions. | 2008-11-27 |
20080292722 | Food preservation compositions and methods - A method of disinfecting surfaces said method comprising applying a disinfectant solution to surface to be disinfected and allowing the solvent to evaporate or wiping the excess solution from the surface after a period of time wherein the solution is an antimicrobial metal ion-acid solution. | 2008-11-27 |
20080292723 | Bioactive acid agrichemical compositions and use thereof - Bioactive agrichemical concentrates and compositions having improved bioactivity comprising metal-acid solutions. | 2008-11-27 |
20080292724 | COMPOSITION FOR IMPROVING MEMBRANE COMPOSITION AND FUNCTIONING CELLS - It has now been found that after administration to a diseased person or person that is at risk for developing such disease of a neutraceutical or pharmaceutical composition that comprises:
| 2008-11-27 |
20080292725 | COPPER-FREE FOOTBATH BLEND - Provided is a composition suitable for treating a foot of an animal. The composition comprises zinc sulfate monohydrate, a chloride salt, and an acid, wherein the composition does not comprise copper. Also provided is a method for treating a foot of an animal. The method comprising contacting the foot of the animal with the above composition. | 2008-11-27 |
20080292726 | OPHTHALMIC GALLIUM COMPOSITIONS AND METHODS OF THEIR USE - Provided are ophthalmic pharmaceutical compositions comprising gallium. These compositions are designed primarily for topical ocular and intraocular administration. Also provided are methods of use for the compositions in the treatment of human and veterinary diseases and disorders. Treatable diseases and disorders include adverse conditions of the eye and adnexal tissues of the eye. These adverse conditions comprise inflammatory conditions, infections, cancers, and other pathological conditions. | 2008-11-27 |
20080292727 | Technique for treatment and prevention of fungal diseases in field-grown grains and legumes by application of acid-activated sodium chlorite solution - A technique for reducing fungal disease in growing grain-producing grasses and growing legume plants involves the generation of chlorine dioxide gas by dissolution of sodium chlorite with an activating acid in an aqueous solution, followed by foliar application of the gas to grasses or legume plants growing in fields. The most preferred acid solution contains urea sulphuric acid (monocarbamide dihydrogen sulphate). | 2008-11-27 |
20080292728 | Cosmetic composition - A cosmetic composition effective in skin lightening or skin rejuvenation is provided. The cosmetic composition is characterized by containing sodium ions, potassium ions, calcium ions, magnesium ions, chlorine ions and HCO | 2008-11-27 |
20080292729 | Stabilized Chlorite Solutions in Combination with Fluoropyrimidines for Cancer Treatment - Pharmaceutical compositions for treating neoplastic disorders and uses thereof are provided. Said pharmaceutical compositions comprise stabilized chlorite solutions (e.g. WFIO) and a fluoropyrimidine, 5-FU, or a 5-FU prodrug (e.g. capecitabine, doxifluridine, UFT, S-1, or BOF-A2). The use of the above stabilized chlorite solution in combination with a fluoropyrimidine dramatically improves the quality of life index (QOL) of a patient undergoing cancer chemotherapy. Cancers that can be treated include cancers of the pancreas, gastrointestinal, head, neck, and breast. | 2008-11-27 |
20080292730 | NUTRITIONAL SUPPLEMENT FOR OSTEOARTHRITIS - The present invention relates to a method of treating osteoarthritis by administering a mineral composition in the form of a nutritional supplement, where the mineral composition may contain Smectite, Gypsum, Quartz, Feldspar, Jarosite, Kaolinite and/or Zeolite. | 2008-11-27 |
20080292731 | METHOD FOR PAIN CONTROL - Methods for providing post-operative pain control or relief to a patient are disclosed. Methods include, for example, administering bicarbonate to an area of a patient during a surgical or dental procedure, near completion of a surgical or dental procedure or immediately following a surgical or dental procedure, in an area previously administered or containing a regional or local anesthetic in an amount sufficient to provide the patient with pain control or relief for a period of time after the surgical or dental procedure. | 2008-11-27 |
20080292732 | Plant and Plant Storage Organ Having Glp-1 Derivative Accumulated Therein and Method of Producing the Same - The present invention is to provide a plant and a plant storage organ thereof in which GLP-1 derivatives are accumulated, and a method of producing them in order to develop a method for ingesting orally GLP-1 derivatives at a low cost and to make use of it in diabetic treatment. A transgenic plant or a plant storage organ thereof in which GLP-1 derivatives are accumulated cleavable with a digestive enzyme is produced by a method comprising: integrating into a vector a linked GLP-1s-DNA which comprises tandem repeated “n” DNAs (“n” being an integer of 3 or more) encoding a GLP-1 derivative consisting of GLP-1 (7-36) or of an amino acid sequence of GLP-1 (7-36) in which one or a few amino acids are deleted, substituted and/or added, and C-terminal consists of Arg or Lys, and having GLP-1 activity; introducing the vector into a plant cell; and redifferentiating the obtained transformant. The transgenic plant and the plant storage organ are useful as a pharmaceutical composition or a food or drink for treating or preventing diabetes. | 2008-11-27 |
20080292733 | Antioxidant and Fe2+ Chelating Properties of Herbal Extracts - The present invention is directed to antioxidative and antiproliferative agents containing North American ginseng (proprietary extract HT1001) alone or in combination with | 2008-11-27 |
20080292734 | COMPOSITIONS AND METHODS FOR TREATMENT OF DERMAL SCARRING AND WRINKLING - Compositions and methods for treatment of dermal scarring and wrinkling, by application to the skin of a cosmetically effective amount of | 2008-11-27 |
20080292735 | REGULATING ALKALOIDS - MPO1 and MPO2 can be regulated for either decreasing or increasing alkaloid levels in plants, in particular in | 2008-11-27 |
20080292736 | Bioavailability enhancing activity of carum carvi extracts and fractions thereof - The present invention relates to the use of extracts of | 2008-11-27 |
20080292737 | Cemented Carbide with Ultra-Low Thermal Conductivity - A hard alloy material comprising tungsten carbide in an amount of less than 50 weight percent of the material, titanium carbide in an amount of at least about 30 weight percent, and a binder material of cobalt and nickel. In other aspects of the invention, molybdenum and/or chromium are included to further lower the thermal conductivity of the material. The thermal conductivity of the material of the invention is about 12 Watt/m° K or less. | 2008-11-27 |
20080292738 | MOTOR DRIVEN MOLD - A mold includes a controller and core actuators that may independently drive a plurality of mold cores positioned with the mold. Sensors may be included whereby the mold cores are positioned in the mold core responsive to the sensor feedback. The core actuators may be servomotors and may further include motor controllers, one for each servomotor, for use in actuating the mold cores. | 2008-11-27 |
20080292739 | Glass fiber product for making preform products - Compressed preform products formed from continuous fibers substantially evenly coated with a thermoplastic sizing composition are provided. Preferably, the continuous fibers are glass fibers. Applying a thermoplastic sizing composition to continuous fibers during the formation of the fibers enables a preform to be formed without applying any additional sizing or binder compositions at later stages of the manufacturing of the preform. The thermoplastic sizing composition includes a thermoplastic material, and, optionally a silane coupling agent. The thermoplastic material in the thermoplastic sizing composition includes chemicals and/or compounds that are thermoplastic or possess thermoplastic properties. One or more preforms may be randomly inserted to a muffler cavity. Upon the application of heat, the preforms decompress and fill the cavity with fibrous material. Due to the ability to decompress the compressed preform product, the preform product can have a shape that is independent of the shape of the muffler cavity. | 2008-11-27 |
20080292740 | SHEET/FILM MOLDING APPARATUS AND SHEET/FILM MOLDING METHOD - A sheet/film molding apparatus includes: a main roll sandwiches and presses, with a touch roll, a resin molten sheet and conveys the sandwiched and pressed resin sheet; and a separating roll separates the resin sheet from an outer peripheral surface of the main roll and conveys the resin sheet. The separating roll has a rubber roll and a metal elastic external cylinder having the rubber roll housed therein and being eccentrically positioned to the rubber roll and thin and easily elastically deformed. Cooling water is supplied between the rubber roll of the separating roll and the metal elastic external cylinder. The resin sheet between the main roll and the metal elastic external cylinder is cooled by allowing the rubber roll to make pressure contact with an inner peripheral surface thereof. The separating roll separates the resin sheet from the outer peripheral surface of the main roll. | 2008-11-27 |
20080292741 | METHOD AND APPARATUS FOR MASS CUSTOMIZED MANUFACTURING - Embodiments of the invention provide a method and apparatus for manufacturing dental aligners. The system includes a workpiece introduction system having at least one workpiece preparation chamber. The system further has a mold manipulation system, having a mold introduction chamber, where a series of different molds may be introduced one after the other; a mold preparation chamber; a workpiece operation chamber; and a mold manipulator to move the mold between the mold introduction chamber, the mold preparation chamber, and the workpiece operation chamber; and a workpiece manipulator to move the workpiece between the workpiece preparation chamber and the workpiece operation chamber. In operation, the method includes steps of inserting a first workpiece into a workpiece preparation chamber; preparing the first workpiece for processing by subjecting the first workpiece to at least one preparation process; moving the first workpiece into a workpiece operation chamber; moving a first mold into a mold preparation chamber; preparing the first mold for processing by subjecting the first mold to at least one preparation process; moving the first mold into the workpiece operation chamber; moving the first mold and the first workpiece into cooperative engagement; subjecting the first workpiece to a vacuum on the side of the first workpiece facing the first mold; and repeating the above steps for a second workpiece and a second different mold. | 2008-11-27 |
20080292742 | Method for conveying polymer - A method for transferring molten polymer through a chute having sharp internal corners, the chute bridging spaced apart processing units, wherein at least the internal corners of the chute are rounded and smoothed to at least a mirror shine. | 2008-11-27 |
20080292743 | SHAPING DIE FOR CHIP PACKAGE LEADS - Disclosed herein is a shaping die for chip package leads including a base portion, on which lead pressing portions are provided, the lead pressing portions having contact portions contacting with TSOP package leads, a groove for holding the TSOP package being formed between the lead pressing portions, wherein the depth of the groove, which is the minimum distance between a location of the groove where the TSOP package is held and the contact portions of the lead pressing portions, corresponds to the maximum distance between the leads and the surface of the TSOP package held by the groove. The flatness of the shaped leads in the invention is improved and the package will not be damaged during the shaping procedure. | 2008-11-27 |
20080292744 | Mold a secondary molding - A mold for a secondary molding includes a lower mold insert, an upper mold insert coupled to the lower mold insert, and an extraction device loaded in the lower mold insert. The lower mold insert has a lower container, a couple of lower notches adjacent to the two opposite sides of the lower container respectively and a lower cavity with two opposite sides connected to the lower notches respectively. The extraction device has an inserting core. The inserting core includes a body with two molding portions at its opposite sides. The body is inserted into the lower container, the molding portions project into the lower cavities. | 2008-11-27 |
20080292745 | Mold Structure and Method of Manufacture Thereof - Disclosed are a mold gate insert as well as a mold assembly and an injection molding machine incorporating such a mold gate insert. The mold gate insert comprises a base structure formed of a wear resistant material having a first thermal conductivity. The base structure defines a mold cavity, at least in part, a nozzle assembly alignment portion for aligning a nozzle assembly with respect to the base structure, and a gate for communication between the mold cavity and the nozzle assembly. The mold gate insert further comprises a heat dam being completely enclosed by the base structure. The heat dam is made of a material having a second thermal conductivity being less than the first thermal conductivity and arranged within the base structure in proximity to the nozzle assembly alignment portion such that the heat flow between the nozzle assembly and the base structure is impeded. Furthermore, a method of producing the mold gate insert is disclosed. | 2008-11-27 |
20080292746 | Valve Pin Bushing Having Thermally Insulative Component - A valve pin bushing for a hot runner includes a bushing body having a hole therethrough for receiving a valve pin and a rearward surface for contacting a back plate. A thermally insulative component is coupled to a forward surface of the bushing body. The thermally insulative component is made of a nonmetallic material having a thermal conductivity lower than that of the bushing body. | 2008-11-27 |
20080292747 | MODIFIED AMYLASE FROM PSEUDOMONAS SACCHAROPHILIA - Described is a PS4 variant polypeptide derivable from a polypeptide having amylase activity selected from: (a) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 161, 178, 179, 223, 229, 272, 303, 307, 309 and 334; (b) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 145, 146, 157, 178, 179, 223, 229, 272, 303, 307 and 334; (c) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; and (d) a polypeptide comprising an amino acid mutation at each of positions 3, 33, 34, 70, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; referring to the numbering of a | 2008-11-27 |
20080292748 | PROCESS FOR PRODUCTION OF AN EFFERVESCENT ALCOHOLIC BEVERAGE - The present invention provides a process for production of an effervescent alcoholic beverage, the process comprising: a pH adjusting step in which the pH of a yeast-containing fermentate obtained by fermenting the raw material of an effervescent alcoholic beverage with the yeast is adjusted, and a storage step in which the fermentate is aged to yield an aged liquor. According to the present invention, it is possible to produce an effervescent alcoholic beverage which has a low hydrogen sulfide concentration and an excellent flavor without using gene recombination, while avoiding adverse effects on the main fermentation step. | 2008-11-27 |
20080292749 | Aromatization of a Milk Product Using at Least One Bacterium Producing a Bacteriocin and Belonging to the Pediococcus Genus - The invention relates to the use of at least one bacteria producing a bacteriocin and belonging to the | 2008-11-27 |
20080292750 | Method of Preparing a Food Ingredient and Food Product Having Angiotensin-I-Converting
Enzyme Inhibiting Properties and Products Thus Obtained - The invention relates to a method of preparing a food ingredient conferring angiotensin-I-converting enzyme inhibiting properties to the food product comprising the ingredient, which method comprises providing a preparation of one or more protein hydrolysates having angiotensin-I-converting enzyme inhibiting properties, optionally together with one or more other constituents; adding one or more microorganism species to the preparation thus provided; and fermenting the preparation. The ingredient thus obtained has ACE-inhibiting properties and is no longer bitter tasting. The de-bittering can also take place directly in the food product for which the ingredient is intended. | 2008-11-27 |
20080292751 | Lactic Acid Bacteria Fermented Substance and Fermented Milk Food Product Containing the Same - An object of the invention is to provide a lactic acid bacteria fermentation product, which has been obtained by culturing lactic acid bacteria on a medium containing an extract of at least one food material selected from the group consisting of rice bran, persimmon leaves, | 2008-11-27 |
20080292752 | Manufacturing Method of Soybean Paste by Protease and Its Processed Products - The present invention relates to a medium composition comprising fermented Korean hot pepper paste, undiluted solution of brewed soy sauce or acid hydrolyzed soy sauce, and a method for producing gamma-aminobutyric acid (GABA) using the medium. More precisely, the present invention relates to a medium composition for culturing lactobacillus having GAD activity, the composition comprising fermented hot pepper paste, brewed soy sauce or acid hydrolyzed soy sauce, and a method for producing a high concentration of gamma-aminobutyric acid from the medium additionally added with glutamic acid or glutamate. The present invention provides a method of producing a high concentration of gamma-aminobutyric acid using the above medium with low production costs. Since the by-products of pastes are used as medium compositions, this medium itself can be added to other pastes or foods to produce functional foods containing gamma-aminobutyric acid. | 2008-11-27 |
20080292753 | Polypeptides Having Phytase Activity and Polynucleotides Encoding Same - The invention relates to a phytase derived from | 2008-11-27 |
20080292754 | Instant Food Comprising Flavour Capsules - The present invention relates to instant food products of flavor capsules that include yeast and, encapsulated therein, a flavoring ingredient or composition wherein the instant food has a water content of 13 wt % or less. The instant food may be a soup, noodles or a seasoning or topping. | 2008-11-27 |
20080292755 | Alkali Buffer + Minerals Supplement Additive - The disclosure herein has applicability to a highly concentrated alkali buffers+minerals supplement solution is formed by combining potassium hydroxide (KOH) with sodium hydroxide (NaOH) with magnesium carbonate hydroxide (MgCO | 2008-11-27 |
20080292756 | Infusion cup - An infusible cup includes a cup body having protruding stop members inwardly protruded from the inside wall, an infusible material contained in the cup body below the elevation of the protruding stop members, and a screen plate mounted inside the cup body and stopped below the protruding stop members above the infusible material for stopping the infusible material inside the cup body when the infusible material is infused with hot water. | 2008-11-27 |
20080292757 | Method of Production a Sweet, a Forming Core for Production a Sweet Shell and a Sweet Produced by the Same Method - The method of production of sweet comprises shell ( | 2008-11-27 |
20080292758 | Method of Monitoring the Breaking of Eggs, an Egg Receiving Device for Holding the Contents of an Egg, and an Egg Breaking Apparatus Comprising Such an Egg Receiving Device - The invention relates to a method and an apparatus for monitoring the breaking of eggs. The eggs are fed to a plurality of egg breaking devices by means of a feeder, each egg breaking device receiving one egg at a time, whereupon the shell of each egg are broken by means of the respective egg breaking device and the contents of each egg are collected in an egg receiving device, each egg receiving device receiving the contents of only one egg in each process cycle. The remains held by each egg breaking device after the breaking of the eggshell are discharged to a waste receptacle, and the contents of the egg receiving device are discharged into one or more product receptacles. The monitoring consists in that the presence of at least one of the conditions (a) the egg is dropped, (b) eggshell is unbroken or (c) yolk membrane is broken is registered automatically, and that the presence of an abnormality in the egg-breaking is presented to an operator. The presence of an unbroken egg may be detected as the lack of contents in the egg receiving device, whereas the presence of an egg with a broken yolk membrane may be detected by the presence of yolk in the albumen. | 2008-11-27 |
20080292759 | Apparatus and Method for Processing and Distribution of Peishable Food Products - A method of processing and distributing perishable food products, including the steps of processing the primals and storing in a central location until ordered, a method of containerization of meat products including compression and storage, a method of processing meat products including chilling and monitoring demand, for the meat, a method of processing food products including modifying the atmosphere in the container and altering pressure as necessary, a method of loading containers into a vehicle comprising separate conveying means for loading and unloading, and a conveyor sorting apparatus having an endless belt and an article contacting surface moving substantially perpendicular to the primary conveyor. | 2008-11-27 |
20080292760 | Semi-Solid Food Products and Methods For Their Production, Based on Inhibiting Amylase Starch Breakdown - The present invention relates to the field of food production, in particular to methods of producing improved semi-solid food products and to the improved semi-solid food products themselves and their use. In particular, in-mouth salivary amylase induced starch breakdown is inhibited. | 2008-11-27 |
20080292761 | Steam Cooking Method and Oven with an Improved Water Supply - The inventive steam cooking method is designed to be carried out in a cooking oven ( | 2008-11-27 |
20080292762 | METHOD FOR PRODUCING DRIED MICROBIAL CELLS - An inexpensive heat treatment method for producing dried microbial cells is provided, wherein the method does not result in lowering the quality of the microbial cells or causing pulverization. The method includes a step of heating microbial cells to between 200 to 450° C. for 1 to 30 seconds. | 2008-11-27 |
20080292763 | Substituted Cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance - The present invention relates to the use of a compound of formula (I) or a mixture of compounds of formula (I) | 2008-11-27 |
20080292764 | Stevioside Polymorphic and Amorphous Forms, Methods for Their Formulation, and Uses - Exemplary embodiments of this invention encompass a method for purifying a substantially crude stevioside, methods for preparing polymorphic and amorphous forms of stevioside, and the polymorphic and amorphous forms prepared therefrom. | 2008-11-27 |
20080292765 | Sweetness Enhancers, Sweetness Enhanced Sweetener Compositions, Methods for Their Formulation, and Uses - The present invention relates generally to sweetness enhancers capable of enhancing the sweet taste of sweetener compositions and the sweetener compositions produced therefrom. In particular, the present invention relates to sweetener compositions comprising sulfamates capable of enhancing the sweetness of the sweetener composition. | 2008-11-27 |
20080292766 | Edible Composition Comprising a Slowly Digestible or Digestion Resistant Oligosaccharide Composition - An edible composition comprises (1) a starch-derived soluble fiber composition that comprises oligosaccharides that are digestion resistant, oligosaccharides that are slowly digestible, or a combination thereof, and (2) at least one material selected from fructose, sorbitol, pullulan, a non-nutritive high-intensity sweetener, and combinations of any two or more thereof. | 2008-11-27 |
20080292767 | BOTTLED BEVERAGE - A packaged beverage with a green tea extract mixed therein, which contains (A) a non-polymer catechin, (B) oxalic acid or a salt thereof, and (C) caffeine, where the content weight ratio (B)/(A) is from 0.00005 to 0.1, and the content weight ratio (A)/(C) is from 5 to 10000. The packaged beverage contains catechins at high concentration, is reduced in bitterness and astringency and is suited for long-term drinking, is excellent in the stability of bitterness and astringency and also in the feeling as it passes down the throat, and further, remains stable in its color tone even when filled in a clear container and stored at high temperatures. | 2008-11-27 |
20080292768 | LOW-CARBOHYDRATE DAIRY PRODUCT - A reduced carbohydrate fermented dairy product having less than 4.9% carbohydrate, a viscosity ranging from 900-1,600 mPa·s and a pH ranging from 4.1 to 4.5 which may be a fermented dairy product produced using ultrafiltered milk, a low carbohydrate or low glycemic sweetener, and a fruit preparation. | 2008-11-27 |
20080292769 | Method and Composition of Making Pasta with Konjac Flour as a Main Ingredient - This invention discloses the method and composition of making pasta with konjac flour as a main ingredient. The composition includes konjac flour (4-12%), durum wheat flour (48-66%), and water (25-35%). The method comprises of mixing konjac flour with water, which is mixed with durum wheat flour subsequently, kneading, extruding and drying in 3 steps. The finale product has physical characters similar to that of the conventional pasta, whereas the health benefits associated with konjac is retained. | 2008-11-27 |
20080292770 | Solid Milk and Method for Manufacturing Thereof - The object of the present invention is to provide solid milk having suitable solubility and strength and a method for manufacturing such solid milk. | 2008-11-27 |
20080292771 | Meat and Stock Recovery Process and Products Thereof - The present invention is directed to the recovery of meat and stock from offal and the generation of enriched stock products derived from selected fractions arid products of this meat recovery process. Specifically the present invention relates to a meat recovery process comprising the general steps of collecting offal material, cooking the offal material in water, decanting the cooked material into a solids fraction and a liquor fraction, separating the solids fraction into meat material and bone material using a non-destructive gravity separation method and delivering said meat material and said bone material for further processing and reducing the water content of the liquor fraction to produce a concentrated stock product, Additionally, according to another aspect the present invention also discloses a process for making an enriched stock product comprising a collagen rich fraction. | 2008-11-27 |
20080292772 | BOTTLED BEVERAGE - A packaged beverage with a green tea extract mixed therein, which contains (A) a non-polymer catechin, and (B) from 0.0001 to 20 wt %, in terms of equivalent glucose amount, and less than 0.05 wt %, in terms of equivalent fructose amount, of a carbohydrate, wherein the packaged beverage has a pH of from 2 to 6. The packaged beverage contains catechins at high concentration, is reduced in bitterness and astringency and is suited for long-term drinking, is excellent in the stability of bitterness and astringency and also in the feeling as it passes down the throat, and further, remains stable in its color tone over a long term even when filled in a clear container and stored at high temperatures. | 2008-11-27 |
20080292773 | Stable starches for contributing dietary fiber to food compositions - The present invention relates to the use of a modified starch to increase the dietary fiber content of food compositions processed under harsh conditions. By using certain modified starches, food formulations may be harshly processed while retaining substantial dietary fiber. Further, such modified starches provide dietary fiber without the negative effects on textural or organoleptic properties of the food compositions which are typically associated with the addition of other dietary fiber sources. | 2008-11-27 |
20080292774 | Liquid Transition Nutrition For Infants - Liquid composition suitable for supporting the transition period wherein the infant changes from a diet consisting of breast milk or liquid infant formula to solid foods with a viscosity 20-150 mPas, containing a digestible carbohydrate fraction and an indigestible carbohydrate fraction with at least 50 wt. % soluble indigestible oligosaccharide with a degree of polymerisation (DP) between 2 and 100. | 2008-11-27 |
20080292775 | Delivery Systems for Natural High-Potency Sweetener Compositions, Methods for Their Formulation, and Uses - The present invention provides substantially water soluble, substantially non-dusting delivery systems for natural high-potency sweeteners, methods for their formulation, and uses. In particular, the present invention relates to different delivery systems of sweetener compositions comprising at least one non-caloric or low-caloric natural high-potency sweetener. | 2008-11-27 |