47th week of 2012 patent applcation highlights part 50 |
Patent application number | Title | Published |
20120296081 | Carrageenan Based Antimicrobial Compositions - Disclosed are compositions for inhibiting transmission of a sexually transmitted infection that contain one or more carrageenans, including lambda carrageenan. Also disclosed are methods for making and using the compositions. | 2012-11-22 |
20120296082 | Oxo-Titanylphthalocyanine Crystal, Method for Producing the Same and Electrophotographic Photoreceptor - The invention provides an oxo-titanylphthalocyanine crystal which is stable, is superior in dispersibility in a photoreceptive layer and efficiently contributes to improvements in sensitivity and charge retention rate of an electophotographic photoreceptor when it is used as a charge generating agent, a method for producing the oxo-titanylphthalocyanine crystal, and an electrophotographic photoreceptor the oxo-titanylphthalocyanine crystal has predetermined optical characteristics and thermal properties and is produced by a production method including the following steps (a) to (d): (a) a step of dissolving a crude oxo-titanylphthalocyanine crystal in an acid to obtain an oxo-titanylphthalocyanine solution; (b) a step of adding the oxo-titanylphthalocyanine solution dropwise in a poor solvent to obtain a wet cake; (c) a step of washing the wet cake with an alcohol having 1 to 4 carbon atoms; and (d) a step of stirring the washed wet cake under heating in a nonaqueous solvent to obtain an oxo-titanylphthalocyanine crystal. | 2012-11-22 |
20120296083 | THREE-DIMENSIONAL STRUCTURE AND METHOD OF PRODUCING THE SAME - The three-dimensional structure of the present invention is a three-dimensional structure formed on a base. This three-dimensional structure contains a plurality of porphyrins, a plurality of first metal ions, and a plurality of specific organic molecules. The porphyrin contains two or more functional groups. The first metal ion is a metal ion for linking the functional group of one porphyrin to the functional group of another porphyrin. The above specific organic molecule is an organic molecule that forms a coordinate bond with a metal ion contained in the two-dimensional structure and that has only one site to coordinate to the metal ion. | 2012-11-22 |
20120296084 | Carbapenem Antibacterials with Gram-Negative Activity and Processes for Their Preparation - The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents. | 2012-11-22 |
20120296085 | CHEMILUMINESCENT DYES AND DYE-STAINED PARTICLES - Chemiluminescent compounds that can be activated by reaction with chemical or photochemical sources of singlet oxygen are provided. At certain temperatures, such as from approximately 15 to 60° C., the compounds slowly return to their deactivated state by emitting visible and/or infrared light that is observable with various types of light detectors. Suitable conjugates of these compounds, or small particles containing these compounds, may be used for chemiluminescence imaging and sensing technologies. In particular, embodiments provide optical molecular imaging using novel squaraine rotaxane endoperoxides (SREPs) and squaraine catenane endoperoxides (SCEPs), interlocked fluorescent and chemiluminescent dye molecules that have a squaraine chromophore encapsulated inside a macrocycle endoperoxide. The dyes may be stored at low temperature, such as below 0° C., but, upon warming above 15° C., such as to body temperature, they undergo a unimolecular cycloreversion reaction that releases singlet oxygen and emits visible or near-infrared light that can pass through living tissue. The chemiluminescent signal is detectable with inherently high contrast because there is negligible background emission. | 2012-11-22 |
20120296086 | RUTHENIUM COMPLEX-BASED PHOTOSENSITIZER DYES FOR DYE-SENSITIZED SOLAR CELLS - This invention relates to ruthenium complex-based photosensitizer dyes for dye-sensitized solar cells, which have a general structural formula represented by formula (I). | 2012-11-22 |
20120296087 | MORPHOLINO-BASED ANTISENSE AGENT - Morpholino-based oligomers suitable as antisense agent comprising modifications of phosphorodiamidate backbone or modification with 5-substituted pyrimidines of morpholino compound that is soluble in culture medium and sufficient for cell penetration thereby eliminating the need for injecting into the cells. Monomers comprising the said oligomers and its method of manufacture, method of manufacture of the said oligomers and its dye, flurophore, drug, biomolecule conjugate wherein the said oligomers find different end use but not limited to regulation of gene expression, tissue culture with improved transfection efficiency and related studies on cellular transfection. | 2012-11-22 |
20120296088 | SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE INHIBITORS - Disclosed is a novel enantiomeric synthesis ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis. | 2012-11-22 |
20120296089 | INHIBITORS OF BRUTON'S TYROSINE KINASE - Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase. | 2012-11-22 |
20120296090 | Drug Repositioning Methods For Targeting Breast Tumor Initiating Cells - Disclosed are systems biology-based methods for repositioning known pharmaceutical compounds to new indications, through the identification of network-based signatures. In particular, the invention provides new and useful methods for selecting drugs or combinations of drugs (and preferably previously-approved drugs) for use in new therapeutic indications. Also disclosed are methods for identifying anti-breast tumor initiating cell (TIC)-based therapeutics from within populations of target compounds. In illustrative embodiments, the invention provides methods and computer programs for the repositioning of FDA-approved pharmaceutical compounds to new indications using network-based signature analysis coupled with conventional in vitro and in vivo testing of identified drug candidates. The invention also allows identification of drugs or drug combinations for treating unmet medical needs including, for example, “orphan” diseases. | 2012-11-22 |
20120296091 | POLYMORPHS - The invention relates to polymorphous crystal modifications of a DPP-IV inhibitor, the preparation thereof and the use thereof for preparing a medicament. | 2012-11-22 |
20120296092 | Molecular Cobalt Pentapyridine Catalysts for Generating Hydrogen from Water - A composition of matter suitable for the generation of hydrogen from water is described, the positively charged cation of the composition including the moiety of the general formula. [(PY5Me | 2012-11-22 |
20120296093 | EXO- AND DIASTEREO- SELECTIVE SYNTHESIS OF HIMBACINE ANALOGS - This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by the following: | 2012-11-22 |
20120296094 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME - The present invention provides a new amide compound and salt thereof that is capable of inhibiting biofilm formation or removing deposited biofilms. The present invention also provides a biofilm formation inhibitor or a biofilm remover containing the amide compound or salt thereof as an active ingredient. | 2012-11-22 |
20120296095 | METHOD FOR PREPARING ORGANIC/INORGANIC HYBRID FUNCTIONALIZED SOLIDS HAVING A TRIAZOLE RING - A process is described for the preparation of a functionalized hybrid solid with an organic-inorganic matrix, crystallized, bearing at least one reactive group based on a triazole ring, from a hybrid solid with an organic-inorganic matrix, MOF—NH | 2012-11-22 |
20120296096 | COMPOUNDS CONTAINING PERFLUOROALKYL-CYANO-ALKOXY-BORATE ANIONS OR PERFLUOROALKYL-CYANO-ALKOXY-FLUORO-BORATE ANIONS - The present invention relates to compounds containing perfluoroalkyl-cyano-alkoxy-borate anions or perfluoroalkyl-cyano-alkoxy-fluoro-borate anions, ((per)fluoro)phenyl-cyano-alkoxy-borate anions or ((per)fluoro)phenyl-cyano-alkoxy-fluoro-borate anions or phenyl-cyano-alkoxy-borate anions which are monosubstituted or disubstituted with perfluoroalkyl groups having 1 to 4 C atoms or phenyl-cyano-alkoxy-fluoro-borate anions which are monosubstituted or disubstituted with perfluoroalkyl groups having 1 to 4 C atoms, the preparation thereof and the use thereof, in particular as part of electrolyte formulations for dye sensitized solar cells. | 2012-11-22 |
20120296097 | PREPARATION METHOD OF ORIGINAL DYE OF VAT BROWN R - A preparation method of original dye of Vat Brown R comprises the following steps: a. after acylation of 1,5-diaminoanthraquinone, 1-amino-5-benzamidoanthraquinone was prepared by acidic hydrolysis; b. 1-benzamido-4-bromoanthraquinone was obtained from 1-aminoanthraquinone by acylation and bromination; c. a condensate of Vat Brown R was obtained by condensation reaction of 1-amino-5-benzamidoanthraquinone and 1-benzamido-4-bromoanthraquinone; d. the original dye of Vat Brown R was obtained from the condensate of Vat Brown R by ring closing reaction and oxidation reaction. The method omits one oxidation step, economizes significant amount of oxidizing agent, and reduces significant amount of waste water, so it is very beneficial to environment protection; and the method also exhibited the advantages of highly increasing product yield and reducing the costs of raw materials to an extent of more than 30%. | 2012-11-22 |
20120296098 | Pentamethine Cyanine Fluorescent Dye with N-substituting at Beta-Position of Conjugated Chain - A pentamethine cyanine fluorescent dye with N-substituting at β-position of conjugated chain is disclosed. The dye reacts with biosubstrate including protein, liposome and DNA, and shows excellent selectivity. It has good living cell membrane permeability and shows good selectivity in living cell staining In addition, the dye has good stability and low background fluorescence, and can be used together with other fluorescent dyes having consistent wavelengths for single-channel excitation and multi-channel detection. The dye can be used in the fields of protein labeling and detecting, fluorescence immunoassay and living cell selective imaging and the like. | 2012-11-22 |
20120296099 | METHODS FOR PREPARING STATIN COMPOUNDS BY LACTONIZATION - A method for preparing a statin compound by lactonization is disclosed, which comprises the following step: lactonizing a compound of formula II into the compound of formula I in the presence of a strong acid catalyst and a dehydrant in a first solvent, | 2012-11-22 |
20120296100 | Manufacturing process for 8-aryloctanoic acids such as Aliskiren - The present invention relates to a novel manufacturing process and novel intermediates useful in the synthesis of pharmaceutically active compound such as Aliskiren. | 2012-11-22 |
20120296101 | PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES - The present invention relates to a process for the preparation of darunavir, a nonpeptide protease inhibitor (PI), useful for the treatment of HIV/AIDS patients harboring multidrug-resistant HIV-1 variants that do not respond to previously existing HAART regimens. The present invention further relates to processes for the stereo-directed preparation of darunavir intermediates, in particular (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol and to certain novel intermediates obtained by such processes. | 2012-11-22 |
20120296102 | METHOD FOR PRODUCING PROPYLENE OXIDE - It is intended to provide a production method for producing propylene oxide from propylene, hydrogen and oxygen, with improved reaction rate. The present invention provides a method for producing propylene oxide, comprising a step of reacting propylene, hydrogen and oxygen, in the presence of a Pd-supported catalyst, a titanosilicate catalyst and a Pd-free carbon material, in a liquid phase. | 2012-11-22 |
20120296103 | NOVEL MIL-53-AL-N3 ORGANIC/INORGANIC HYBRID SOLID PROVIDED WITH AN AZIDE FUNCTION AND METHOD FOR MANUFACTURING SAME - The invention describes a crystallized hybrid solid with an organic-inorganic matrix, of a three-dimensional structure, containing an inorganic network of aluminum-based metal centers that are connected to one another by organic ligands that consist of the entity —O | 2012-11-22 |
20120296104 | CAU-1-N3 ORGANIC-INORGANIC HYBRID SOLID, EQUIPPED WITH AN AZIDE GROUP, AND PROCESS FOR ITS PREPARATION - The invention describes a crystallized hybrid solid with an organic-inorganic matrix, of a three-dimensional structure, containing an inorganic network of aluminum-based metal centers that are connected to one another by organic ligands that consist of the entity —O | 2012-11-22 |
20120296105 | CRYSTALLINE ANHYDRATE FORMS OF A PHARMACEUTICAL - The invention provides and describes solid state 17α-ethynyl-androst-5-ene-3β,7β,17β-triol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol include Form I anhydrate and Form IV and Form V solvates. The invention further relates to solid and suspension formulations containing 17α-ethynyl-androst-5-ene-3β,7β,17β-triol in a described solid state form and use of the formulations to treat hyperglycemic conditions, such as type 2 diabetes and metabolic syndrome, and autoimmune conditions, such as rheumatoid arthritis, ulcerative colitis and type 1 diabetes, among other inflammation related conditions in subjects or human patients. The invention also relates to methods to make liquid formulations from solid state forms of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol and uses of such formulations in treating the described conditions. | 2012-11-22 |
20120296106 | PROCESS FOR PREPARING ORGANOSILANES - The invention relates to a process for preparing diorganyldihalosilanes of the general formula (1) R | 2012-11-22 |
20120296107 | Photoacid Generators for the Synthesis of Oligo-DNA in a Polymer Matrix - Compounds represented by the following structural formulas can be used as photoacid generators: | 2012-11-22 |
20120296108 | PROCESS FOR PRODUCING GEOMETRIC SHAPED CATALYST BODIES - A process for producing geometric shaped catalyst bodies K whose active material is a multielement oxide of stoichiometry | 2012-11-22 |
20120296109 | Levodopa Prodrugs, and Compositions and Uses Thereof - (2R)-2-Phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of using the same to treat diseases or disorders such as Parkinson's disease are provided. | 2012-11-22 |
20120296110 | PROCESS FOR PREPARATION OF PURE ALKYL ESTERS FROM ALKALI METAL SALT OF CARBOXYLIC ACID - The dehydrated alkali metal salts of carboxylic acid are dissolved in the alcohol such as methanol or ethanol or butanol to make their solution in corresponding alcohol. The solution alcohol is further treated with carbon dioxide under pressure or at atmospheric pressure at elevated temperature such as 150 to 200° C. The carboxylic acid gets converted into corresponding alkyl ester and calcium carbonate or sodium carbonate or potassium carbonate as the byproduct. Calcium lactate or Sodium lactate or Sodium acetate or Sodium benzoate or Sodium salicylate as alkali metal salt solution prepared in Methanol or Ethanol or Butanol when treated with carbon di-oxide under pressure or at atmospheric pressure at elevated temperature gets converted to Methyl lactate or Ethyl lactate or Methyl acetate or Methyl benzoate or Methyl salicylate as product. | 2012-11-22 |
20120296111 | CATALYST AND PROCESS FOR HYDROGENATING AROMATICS - The present invention relates to an eggshell catalyst comprising an active metal selected from the group consisting of ruthenium, rhodium, palladium, platinum and mixtures thereof, applied to a support material comprising silicon dioxide, wherein the pore volume of the support material is 0.6 to 1.0 ml/g, determined by Hg porosimetry, the BET surface area is 280 to 500 m | 2012-11-22 |
20120296112 | Neuroprotective Compositions and Methods - Neurite outgrowth-promoting prostaglandins (NEPPs) and other electrophilic compounds bind to Keap1, a negative regulator of the transcription factor Nrf2, and prevent Keap1-mediated inactivation of Nrf2 and, thus, enhance Nrf2 translocation into the nucleus of neuronal cells. Therefore, neuroprotective compositions and related methods are provided that employ such neuroprotective compounds, and prodrugs of such compounds, to cause dissociation of Nrf2 from a Keap1/Nrf2 complex. | 2012-11-22 |
20120296113 | Process For The Preparation Of Thyroid Hormones And Salts Thereof - The present invention generally refers to a process for the preparation of L-thyroxine derivatives. More in particular, the present invention relates to a iodination reaction of an aromatic derivative with an appropriate iodinating agent, so to afford the related iodinated compound as disodium salt, which may represent a useful intermediate for the synthesis of the L-thyroxine mono-sodium salt, and the free form thereof. | 2012-11-22 |
20120296114 | PREPARATION METHOD OF 4-AMINOMETHYLBENZOIC ACID - The present invention relates to a preparation method of 4-aminomethylbenzoic acid comprising the following steps: preparing 4-carboxylbenzaldehyde or an alkyl ester thereof (methyl 4-formyl benzoate); reacting the 4-carboxylbenzaldehyde or an alkyl ester thereof (methyl 4-formyl benzoate) with hydroxyamine to oximate the same; and contact reducing 4-carboxylbenzaldehyde oxime or an alkyl ester oxime thereof obtained by the oximation, through hydrogen in a sodium hydroxide aqueous solution. Since methyl 4-hydroxyiminomethylbenzoate is reacted as a raw material in the presence of an alkali, hydrogen of a relatively low pressure can be used and a purification process is also simple, thereby enabling preparation of 4-aminomethylbenzoic acid with a low cost and high yield. | 2012-11-22 |
20120296115 | METHOD FOR PRODUCING POLYOXYALKYLENE ALKYL ETHER CARBOXYLIC ACID AND SALT THEREOF - The present invention provides a method for producing polyoxyalkylene alkyl ether carboxylic acid and a salt thereof, including supplying polyoxyalkylene alkyl ether, oxygen, and water to a continuous stirred tank reactor containing a noble metal catalyst to oxidize the polyoxyalkylene alkyl ether with oxygen, in which the molar ratio of the salt of polyoxyalkylene alkyl ether carboxylic acid to the polyoxyalkylene alkyl ether in the continuous stirred tank reactor is controlled to 0.33 to 49. | 2012-11-22 |
20120296116 | Process for the Production of L-Citrulline - Processes for producing a suitable purity grade of L-Citrulline are disclosed. The processes can include contacting crude L-Citrulline in an aqueous solution with an adsorptive medium at a temperature above approximately 50° C. and below the temperature of denaturement for the L-Citrulline for an interval sufficient to remove at least one contaminant from the L-Citrulline. The processes can also include concentrating the dissolved L-Citrulline relative to the aqueous solution. | 2012-11-22 |
20120296117 | METHODS FOR PRODUCTION OF HIGH CONCENTRATION OF ARGININE BICARBONATE SOLUTION AT HIGH PRESSURE - Methods of producing arginine bicarbonate solutions in very high concentrations including reacting an arginine slurry containing a first portion of arginine with a source of carbon dioxide gas at elevated pressure and temperature, adding subsequent portions of arginine to the resulting solution and further reacting with compressed carbon dioxide until a final solution containing in excess of 50% by weight are provided which include preparing an arginine solution by subjecting an arginine water slurry to elevated pressure and temperature and reacting the arginine solution with a source of carbon dioxide gas to form a solution comprising arginine and bicarbonate anion and recovering arginine bicarbonate from the solution. | 2012-11-22 |
20120296118 | SODIUM DIFORMATE PRODUCTION AND USE - The invention relates to a method for producing and using a solid sodium diformate having a high formic acid content, to the use thereof in animal foods in the form of an acidifier, preservatives, ensilage auxiliary agents, fertilizers, and a growth and productivity-stimulating agent and the inventive animal food additives containing sodium diformate. | 2012-11-22 |
20120296119 | METHOD FOR PREPARATION OF PERFLUOROALKYL SULFENYL CHLORIDE - The present disclosure provides a process for the preparation of perfluoroalkyl sulfenyl chloride by reacting a compound of formula [I] with at least one fluoride compound and thiophosgene. | 2012-11-22 |
20120296120 | Falling-Film Stripper for Carbamate Decomposition - A stripper (S | 2012-11-22 |
20120296121 | PROCESS FOR PRODUCING CARBON FILLERS HAVING COVALENTLY BONDED AMINO GROUPS - The invention relates to a process for producing carbon fillers having covalently bonded amino groups, by converting a mixture comprising carbon fillers and alkali metals and/or alkaline earth metals and/or amides thereof in liquid anhydrous ammonia, optionally together with an inert solvent, at temperatures of 35 to 500° C. and a pressure of 30 to 250 bar. | 2012-11-22 |
20120296122 | FLUOROETHER-FUNCTIONALIZED AMINOAROMATIC COMPOUNDS AND DERIVATIVES THEREOF - Disclosed are fluoroether-functionalized aminoaromatic compounds and derivatives thereof. The compounds disclosed have utility as functionalized monomers and co-monomers in polyamides, polyoxadiazoles. Incorporation of the monomers into polymers can provide improved soil resistance to articles produced from the polymers. | 2012-11-22 |
20120296123 | FLUOROETHER-FUNCTIONALIZED NITROAROMATIC COMPOUNDS AND DERIVATIVES THEREOF - Disclosed are functionalized fluoroether-functionalized nitroaromatic compounds and derivatives thereof. The compounds disclosed have utility as precursors of functionalized monomers and co-monomers in polyamides, polyoxadiazoles and the like. Incorporation of the monomers into polymers can provide improved soil resistance to articles produced from the polymers. | 2012-11-22 |
20120296124 | Efficient and Recyclable Heterogeneous Nanocatalysts - Efficient and recyclable heterogeneous nanocatalysts and methods of synthesizing and using the same are provided. | 2012-11-22 |
20120296125 | ALKOXYLATION PRODUCTS AND PROCESS FOR PREPARING THEM BY MEANS OF DMC CATALYSTS - Novel alkoxylation products containing lateral hydroxyl groups or bearing lateral C—C double bonds and a process for preparing them by means of an alkoxylation reaction of halogenated alkylene oxides using double metal cyanide (DMC) catalysts and subsequent elimination of chlorine. | 2012-11-22 |
20120296126 | Preparing Method for Xanthophyll Crystals with Higher Content of Zeaxanthin from Plant Oleoresin - The invention makes public a preparing method for xanthophyll crystals with higher content of zeaxanthin from plant oleoresin. The current methods generally are to get quite pure crystal forms of xanthophyll or zeaxanthin, and they refer to several separation steps. The invention mixes the xanthophyll diester-containing plant oleoresins and food grade alcohol solvents to form even solution, and then soap-dissolve the solution under an alkaline environment; then replenish organic solvents and emulsifiers into the reaction solution and drop some alkali solution into the solution to make partial xanthophyll crystals be transformed to be zeaxanthin through epimerization reaction; after the reaction is finished, add the mixed solvents of alcohol solvent and water to separate out the crystals; use the method of centrifugation or filtration to get the crystals; wash the crystals several times with the mixed solution of deionized water and alcohols to remove the impurities among the crystals; recrystallize the gained crystals with absolute ethyl alcohol, and then dry the crystals to get the products. The invention can gain mixture crystals that contain xanthophyll and zeaxanthin at one time in quite high collection rate, and it is convenient for the followed product application. | 2012-11-22 |
20120296127 | INTEGRATED PROCESS FOR THE PRODUCTION OF 1-CHLORO-3,3,3-TRIFLUOROPROPENE - The present invention is directed to processes for the production of 1233zd from 240fa and HF, with or without a catalyst, at a commercial scale. The 240fa and HF are fed to a reactor operating at high pressure. The resulting product stream comprising 1233zd, HCl, HF, and other byproducts is treated to one or more purification techniques including phase separation and one or more distillations to provide purified 1233zd, which meets commercial product specifications, i.e., having a GC purity of 99.5% or greater. | 2012-11-22 |
20120296128 | METHOD FOR SEPARATING HALOCARBONS - The invention provides a method for separating halocarbons. In particular, a method for separating 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) from 2-chloro-3,3,3-trifluoropropene (HCFO-1233xf) based on differences in melting points of these compounds. More particularly the invention pertains to a method for separating HCFC-244bb from HCFO-1233xf which are useful as intermediates in the production of 2,3,3,3-tetrafluoropropene (HFO-1234yf). | 2012-11-22 |
20120296129 | SUBSTANTIALLY NON-POROUS SUBSTRATE SUPPORTED NOBLE METAL-AND LANTHANIDE-CONTAINING CATALYSTS - Aspects of the invention relate to hydrogenation catalysts, and hydrogenation processes using these catalysts, having particular characteristics, in terms of the amount and type of metal hydrogenation component (or catalytic constituent), as well as the support or substrate. The catalyst compositions, comprising both a noble metal and a lanthanide element on a substantially non-porous substrate, provide advantageous performance characteristics, including conversion, selectivity, and activity stability, as demanded in industrial hydrogenation and selective hydrogenation applications. | 2012-11-22 |
20120296130 | METHOD FOR ALKYLATION OF TOLUENE TO FORM STYRENE UTILIZING AN OXY-DEHYDROGENATION REACTOR - A process for making styrene is disclosed that includes reacting toluene with a C | 2012-11-22 |
20120296131 | METHOD FOR ALKYLATION OF TOLUENE IN A PRE-EXISTING DEHYDROGENATION PLANT - A process for making styrene in a pre-existing facility including an infrastructure capable of producing styrene, wherein the infrastructure includes at least one dehydrogenation unit. The process includes coupling an alkylation unit including an alkylation reactor to the infrastructure and contacting toluene with a C | 2012-11-22 |
20120296132 | USE OF AN OXIDANT IN THE COUPLING OF TOLUENE WITH A CARBON SOURCE - A process for making styrene including reacting toluene with a C | 2012-11-22 |
20120296133 | PROCESS FOR TOLUENE AND METHANE COUPLING IN A MICROREACTOR - A process for making ethylbenzene and/or styrene by reacting toluene with methane in one or more microreactors is disclosed. In one embodiment a method of revamping an existing styrene production facility by adding one or more microreactors capable of reacting toluene with methane to produce a product stream comprising ethylbenzene and/or styrene is disclosed. | 2012-11-22 |
20120296134 | GERMANIUM MODIFIED CATALYST FOR COUPLING REACTIONS - A germanium modified catalyst is disclosed that can be prepared by providing a germanium source and a substrate including silica; contacting the substrate with the germanium source; and obtaining a catalyst including germanium. The contacting of the substrate with the germanium source results in the substitution of at least a portion of the silica with germanium to increase the basicity of the catalyst. The catalyst can be used in a process for making styrene that includes reacting toluene with a C | 2012-11-22 |
20120296135 | NITROGEN CONTAINING CATALYST FOR COUPLING REACTIONS - A process for making styrene including providing a C | 2012-11-22 |
20120296136 | PROCESS FOR ALKYLATION OF TOLUENE TO FORM STYRENE AND ETHYLBENZENE - A process is disclosed for making styrene and/or ethylbenzene by reacting toluene with a C | 2012-11-22 |
20120296137 | USE OF A CO-FEED IN THE COUPLING OF TOLUENE WITH A CARBON SOURCE - A process for making styrene is disclosed that includes providing toluene, a co-feed, and a C | 2012-11-22 |
20120296138 | METHOD FOR ALKYLATION OF TOLUENE TO FORM STYRENE AND ETHYLBENZENE UTILIZING A MOVING BED REACTOR - A method is disclosed for making styrene and/or ethylbenzene by reacting toluene with a C | 2012-11-22 |
20120296139 | METHOD FOR PROVIDING A CO-FEED IN THE COUPLING OF TOLUENE WITH A CARBON SOURCE - A process for making styrene is disclosed that includes reacting toluene with a C | 2012-11-22 |
20120296140 | METAL OXIDE CONTAINING CATALYST FOR SIDE CHAIN ALKYLATION REACTIONS - A catalyst containing a zeolite component and a metal oxide component, wherein the metal oxide component is ion-exchanged with the zeolite component resulting in an ion-modified zeolite, and wherein, under reaction conditions, the metal oxide component transforms into other oxide structures. | 2012-11-22 |
20120296141 | ADDITION OF A BASE TO ENHANCE PRODUCT YIELD IN ALKYLATION REACTIONS - A process for making styrene including providing toluene, a co-feed, and a C | 2012-11-22 |
20120296142 | ADDITION OF BASIC NITROGEN TO ALKYLATION REACTIONS - A process for making styrene including providing toluene, a co-feed, and a C | 2012-11-22 |
20120296143 | Process for the Purification of Paraxylene - The proposed process uses crystallization technology to purify paraxylene simultaneously of large concentrations of C8 aromatics and also small concentrations of oxygenated species. | 2012-11-22 |
20120296144 | METHOD OF MAKING LINEAR ALKYLBENZENES - A method of producing a linear alkylbenzene that includes introducing an olefin into an aromatic stream to form a mixture; processing the mixture in a shear device at a shear rate greater than about 20,000 s | 2012-11-22 |
20120296145 | METHODS FOR MONITORING IONIC LIQUIDS USING VIBRATIONAL SPECTROSCOPY - Methods for monitoring ionic liquids using vibrational spectroscopy may involve contacting an infrared (IR) transmissive medium with the ionic liquid, recording an IR spectrum of the ionic liquid, and quantifying at least one chemical characteristic of the ionic liquid based on the IR spectrum. The IR spectrum may be recorded ex situ or in situ. Methods for controlling ionic liquid catalyzed processes are also disclosed, wherein a condition of the ionic liquid may be determined during such processes based on IR spectral analysis of the ionic liquid. | 2012-11-22 |
20120296146 | FLUID CATALYTIC CRACKING PROCESS - One exemplary embodiment can be a fluid catalytic cracking process. The process can include a reaction zone operating at conditions to facilitate olefin production and including at least one riser. The at least one riser can receive a first feed having a boiling point of about 180° to about 800° C., and a second feed having more than about 70%, by weight, of one or more C | 2012-11-22 |
20120296147 | Treatment Apparatus and Methods - Various methods and apparatus are disclosed that relate to one or more aspects of a treatment system that circum-neutralizes the pH of an aqueous stream, removes one or more heavy metals from the aqueous stream, circum-neutralizes the pH of a CCR supply, and/or removes one or more heavy metals from the CCR supply. | 2012-11-22 |
20120296148 | Method and Apparatus Pertaining to Treatment Plans for Dynamic Radiation-Treatment Platforms - A control circuit accesses patient information and treatment-platform information and uses that information to automatically suggest a treatment plan having at least one of a given number of treatment-pathway traversals wherein the given number is permitted to be greater than one and sub-treatment-pathway traversal-based physical alterations to at least one of the dynamic elements of the dynamic radiation-treatment platform. By one approach the aforementioned patient information can refer, at least in part, to the patient's external contour and a treatment target's size and position with respect to the patient. The patient information regarding the treatment target can represent the latter as a simple symmetrical geometric shape (such as a cuboid). The treatment-platform information, in turn, can refer, at least in part, to dynamic elements of the dynamic radiation-treatment platform itself. | 2012-11-22 |
20120296149 | METHODS OF CONTROLLING MAGNETIC NANOPARTICLES TO IMPROVE VASCULAR FLOW - Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. | 2012-11-22 |
20120296150 | PORTABLE APPARATUS FOR LOCAL COMBINED ELECTROMAGNETIC IRRIDATION - The present invention relates to the electromagnetic field physiotherapy and may be used for treating and preventing various diseases and disorders. | 2012-11-22 |
20120296151 | ASSEMBLY AND METHOD OF IMPLANTING A HEART ASSIST SYSTEM - A needle guard is used when suturing the cuff of an attachment ring to the heart. The needle guard is disposed in the attachment ring to prevent other parts of the attachment ring from being punctured by a suturing needle. The needle guard can include one or more grooves to inhibit relative movement between the needle guard and the attachment ring during suturing. The needle guard is removed upon completion of suturing and to allow insertion into attachment ring of an inflow conduit of a heart assist device. An articulated clamp is used to compress the attachment ring into engagement with the inflow conduit. The attachment include an annular rib that grabs the inflow conduit. | 2012-11-22 |
20120296152 | MULTI-LUMEN CANNULA - This document relates to methods and materials for providing blood flow for a blood pump recipient. For example, cannulae that can be connected to the circulatory system of a mammal and can be used in conjunction with a blood pump (e.g., an assist device) are provided. | 2012-11-22 |
20120296153 | METHODS AND DEVICES FOR DIASTOLIC ASSIST - The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff. | 2012-11-22 |
20120296154 | METHODS AND APPARATUS FOR TRANSMITTING VIBRATIONS - Methods and apparatus for transmitting vibrations via an electronic and/or transducer assembly through a dental implant are disclosed herein. The assembly may be attached, adhered, or otherwise embedded into or upon the implant to form a hearing assembly. The electronic and transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure. | 2012-11-22 |
20120296155 | Magnetic Attachment Arrangement for Implantable Device - An arrangement is described for an implantable medical system. An implant housing contains a portion of an implantable electronic system and has a planar outer surface adapted to lie parallel to overlying skin in an implanted patient. An implant magnet arrangement is located within the housing and adapted to magnetically interact with a corresponding external magnet in an external device on the skin of the implanted patient over the implant housing. The implant magnet arrangement includes an inner center disc having a magnetic dipole parallel to the planar outer surface of the implant housing with an inner magnetic orientation in an inner magnetic direction, and an outer radial ring having a magnetic dipole parallel to the planar outer surface of the implant housing with an outer magnetic orientation in an outer magnetic direction opposite to the inner magnetic direction. | 2012-11-22 |
20120296156 | Sleep and Environment Control Method and System - A sleep system is provided that aids in achieving a sleep goal through the control of an environment near a person. The sleep system includes a processor capable of executing instructions used for controlling one or more aspects of the environment and a memory capable of holding the instructions. Upon executing the instructions, the sleep system receives a sleep goal for the person that includes varying the nearby environment. The processor may further execute instructions to create settings that vary at least one environmental condition of the environment over time as it relates to one or more cycles of a sleep architecture for the person. Varying at least one environmental condition near the person experiencing one or more cycles of the sleep architecture influences the quality of the person's sleep. The sleep system may further adjust at least one environmental condition in the vicinity of the person in accordance with the sleep architecture for the person. | 2012-11-22 |
20120296157 | MEDICAL DEVICE COMPRISING AN ARTIFICIAL CONTRACTILE STRUCTURE - The present invention relates to a medical device including an artificial contractile structure which may be advantageously used to assist the functioning of a hollow organ. The medical device includes an artificial contractile structure including at least one contractile element ( | 2012-11-22 |
20120296159 | SUPPORTING APPARATUS FOR MEDICAL DEVICE - A supporting apparatus for medical device comprises a balance mechanism which movably and tiltably maintains a flexible endoscope and balances a weight of the flexible endoscope and a link mechanism section. Further, the supporting section of the flexible endoscope comprises a transparent photo interrupter which detects attachment/detachment of the flexible endoscope, and the supporting apparatus for medical device is provided with a controller which outputs a control signal to switch lock sections to a fixed state, based on a detection signal from the photo interrupter, when the flexible endoscope is detected to be detached from the supporting section by the photo interrupter. | 2012-11-22 |
20120296160 | Positioning Cage - A positioning device and method of using are provided herein. The positioning device includes an expandable cage through which blood can flow. The expandable cage is insertable into a bodily organ, for example a heart, and expanded to temporarily secure the positioning device within the organ. Then, the cage can be used to steady the implantation of an annuloplasty device, for example. Alternatively, the expanded cage can be used to locate a desired area or feature of the body organ in which it is inserted by way of fluoroscopy. | 2012-11-22 |
20120296161 | BALLOON VISUALIZATION FOR TRAVERSING A TISSUE WALL - Systems and methods for controllably traversing a tissue wall. In one embodiment, a distal end of a catheter is positioned and/or repositioned utilizing direct visualization out the distal end of the catheter, as facilitated by an imaging element disposed within the distal tip of the catheter. An inflatable balloon may comprise a portion of the distal tip of the catheter for structural and/or visualization media purposes. A tissue traversing element may be forwarded through a working lumen defined by the catheter and controllably pushed through a tissue wall as observed with the imaging element. The tissue traversing element may comprise sensors and the like to facilitate monitoring of changes in pressure, color, oxygen saturation, flow rate, and echo timing, to determine the position of the tissue traversing member relative to the tissue wall. | 2012-11-22 |
20120296162 | Method for Positioning a Disposable Sterile Endotracheal Tube, and Corresponding System for Intubation - The system for intubation comprises:
| 2012-11-22 |
20120296163 | INTEGRATED VISUALIZATION APPARATUS, SYSTEMS AND METHODS THEREOF - Surgical visualization devices are provided which include a fixation device having at least one camera coupled to the fixation device wherein the camera includes at least one lens that is directed outwardly from the upper surface of the fixation device such that when the fixation device is inserted in tissue the at least one lens is oriented away from the tissue for capturing images of the anatomical site. Systems and methods utilizing the surgical visualization apparatus are also provided. | 2012-11-22 |
20120296164 | MONITOR APPARATUS FOR LAPAROSCOPIC SURGERY AND DISPLAYING METHOD THEREOF - A monitor apparatus for a laparoscopic surgery rotates images captured by a laparoscope as an endoscope and displayed on monitors for the laparoscopic surgery clockwise or counterclockwise according to commands for rotating the images by surgeons who use image rotation manipulation parts such that the images of surgical devices displayed on the monitors are arranged in the direction where the surgeons can actually manipulate the laparoscopic surgical devices most conveniently. | 2012-11-22 |
20120296165 | CAPSULE MEDICAL APPARATUS AND METHOD FOR MANUFACTURING THE SAME - A capsule medical apparatus includes: a casing having a capsule shape; first and second boards in at least one of which an imaging element is provided and which are connected by a flexible board; a first board retaining member that retains the first board; a second board retaining member that retains the second board; and a battery arranged between the first and the second board retaining members. The first and the second board retaining members and the battery are housed in an inside of the casing in a state where the battery is put between the first and the second board retaining members which retain the first and the second boards, respectively. A groove part in which the flexible board is arranged is formed on an inner wall of the casing. | 2012-11-22 |
20120296166 | INTRADURAL ENDOSCOPE - A method for treating a patient includes inserting an endoscope into an intradural space of the patient via an interspace of a vertebral column of the patient; steering the endoscope along the intradural space to a location; and performing a medical procedure at the location using a working lumen of the endoscope. | 2012-11-22 |
20120296167 | Flexible-Tubed Structure of Endoscope - The present invention relates to a flexible-tubed structure of an endoscope comprising a plurality of cylindrical units, a first wire, a second wire, a first flexible unit, and a second flexible unit. The wires respectively pass through the cylindrical units. The flexible units are continuously disposed at the recesses of the cylindrical units. The cylindrical units are used to form a tubular unit by the flexible units. The tubular unit is bent by the tension of the first wire or the second wire to control the turning-direction of the camera apparatus. | 2012-11-22 |
20120296168 | Composite Flexible Endoscope Insertion Shaft With Tubular Substructure - An endoscope insertion shaft is disclosed comprising a tubular member having an axis and including at least one aperture for imparting desirable mechanical characteristics to the shaft. A composite, laminated or fused material comprises at least one layer encasing or jacketing the tubular member. | 2012-11-22 |
20120296169 | Articulating Laparoscopic Surgical Access Instrument - A surgical instrument includes proximal and distal shaft components, an articulation assembly, and an outer sleeve. The shaft components are pivotably coupled to one another. The distal shaft component is articulatable relative to the proximal shaft component between a substantially aligned configuration and an articulated configuration. The articulation assembly includes a rack and a pinion gear engaged with one another. The rack and the pinion gear cooperate to permit incremental articulation of the distal shaft component relative to the proximal shaft component between the substantially aligned and articulated configurations. The outer sleeve is disposed about the proximal shaft component and is manipulatable relative to the proximal shaft component between a first position and a second position for articulating the distal shaft component between the substantially aligned configuration and the articulated configuration. | 2012-11-22 |
20120296170 | THORACIC ACCESS PORT - A surgical access assembly for positioning within an opening in tissue including an outer frame positionable outside a patient and defining an opening therein dimensioned to receive a surgical instrument therethrough. The outer frame includes first and second portions. The first portion is biased into locking engagement with the second portion such that a first engagement structure is in locking engagement with a second engagement structure. An inner member is positionable within a patient and a flexible member extends between the inner member and outer member and is operatively associated with the outer member. The first portion is movable to overcome the bias to move the first and second engagement structures to a disengaged position, wherein in the disengaged position at least one of the first and second portions is movable with respect to the other portion to adjust the tension on the flexible member to retract tissue. | 2012-11-22 |
20120296171 | Method and Apparatus for Performing Spinal Fusion Surgery - Implants, instruments, and methods for performing surgical procedures on the spine, including one or more of creating an operative corridor to the spine, delivering implants to the spine, fusing one or more segments of the spine, and fixing one or more segments of the spine. | 2012-11-22 |
20120296172 | SURGICAL RETRACTOR APPARATUS AND METHOD - A surgical retractor is provided to retain tissue in a retracted position and expose an interior surface during a surgical procedure. The surgical retractor is self-retaining and includes opposing blades that are removably mountable on arms of the surgical retractor via a ball-and-socket assembly that permits swiveling and hinging of the opposing blades independent from each other and the arms. Each of the opposing blades have a plurality of talons with a curved surface to slidably receive and partially enwrap bone matter so that the plurality of talons securely engage the bone matter while permitting slidable adjustment therebetween. | 2012-11-22 |
20120296173 | ILLUMINATION DEVICE AND METHOD OF USE FOR OPHTHALMIC SURGERY - An illumination device for use in an ophthalmic surgical apparatus, the illumination device including a fiber optic having a proximal end and a connector coupled to the fiber optic. The connector includes one or more of (1) a datum surface disposed a predetermined distance from the proximal end to position the proximal end at a predetermined location within the surgical apparatus, (2) a shutter actuation surface configured and arranged to open a shutter in the surgical apparatus when the connector is being connected to the surgical apparatus, and (3) a visual indicator position to provides a visual indication that the connector is fully inserted into the surgical apparatus. The illumination device may be in a combination with an ophthalmic surgical apparatus. | 2012-11-22 |
20120296174 | MODULAR WRIST-WORN PROCESSOR FOR PATIENT MONITORING - The invention provides a physiological probe that comfortably attaches to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe, which comprises a separate cradle module and sensor module, secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. The cradle module, which contains elements subject to wear, is preferably provided as a disposable unit. | 2012-11-22 |
20120296175 | Methods and apparatus for assessment of atypical brain activity - In exemplary implementations of this invention, sensor measurements are taken before, during and after an epileptiform seizure of a human. The sensors measure electrodermal activity (EDA) and heart rate variability (HRV) of the human. | 2012-11-22 |
20120296176 | METHOD AND APPARATUS FOR DIAGNOSIS AND TREATMENT - Method and apparatus for performing multiple measurements and diagnoses simultaneously, in terms of body function, include a data processing element, a data acquisition module, an optional treatment output module, a user control module, and a user display system, where the data acquisition module sends a plurality of measurement data simultaneously, in terms of body functions, to the data processing element. The processing element provides a plurality of outputs which can be made available to the user or combined in the diagnostic module. A treatment algorithm in the treatment module can affect the patient through a feedback mechanism. In response, the data processing element generates treatment information needed by the treatment output module. | 2012-11-22 |
20120296177 | SYSTEMS AND METHODS FOR DERIVING RELATIVE PHYSIOLOGIC MEASUREMENTS - One embodiment of the present invention relates to a system for deriving physiologic measurement values that are relative to ambient conditions. In one embodiment, the system comprises an implantable medical device (“IMD”), an external computing device, and a backend computing system. The IMD determines a physiologic parameter value within a patient's body, and communicates the physiologic parameter value outside the patient's body, for example, to the external computing device. Further, the external computing device receives the physiologic parameter from the IMD and communicates it to the backend computing system. The backend computing system receives the physiologic parameter value and obtains an ambient condition value outside the body. The backend computing system then calculates a relative physiologic parameter value from the ambient condition value and the physiologic parameter value, and in some embodiments, stores the relative physiologic parameter value in a storage location, such as a memory or database. | 2012-11-22 |
20120296178 | PERSONAL HEALTH DEVICE - An active pulse blood constituent monitor is disclosed. A sensor configured to provide an artificial excitation to a portion of the patient at a known frequency provides additional information in determining the physiological condition of the patient. | 2012-11-22 |
20120296179 | ANALYTE CONCENTRATION DETECTION DEVICES AND METHODS - Arrangements for the detection of the presence and/or concentration of an analyte in a sample of bodily fluid include diffuse transmission, diffuse reflection and edge or waveguide illumination arrangements. A vertical flow assay arrangement and/or technique is also disclosed, and includes a detection component that can be in the form of an array of optical detection elements. A number of assay pad constructions are described which may include at least one or more of the following components: a prefilter component, a reflective component, a membrane component, a reagent component, a mesh component, and a component to prevent lateral spreading. | 2012-11-22 |
20120296180 | SPECTROSCOPIC DETECTION OF MALARIA VIA THE EYE - Methods, apparatus, and systems for detecting hemozoin and diagnosing malaria infection are disclosed. | 2012-11-22 |
20120296181 | SYSTEM AND METHOD FOR VOICE CONTROL OF MEDICAL DEVICES - A medical device includes an insertable portion capable of being inserted into an orifice associated with a body of a patient. The insertable portion comprising an automated head unit capable of being manipulated in at least two axes of motion based at least in part on one or more control signals. The medical device further includes one or more controllers coupled to the automated head unit. In one particular embodiment, the one or more controllers generate the one or more control signals based at least in part on an input signal. | 2012-11-22 |