46th week of 2013 patent applcation highlights part 55 |
Patent application number | Title | Published |
20130303708 | Fluoropolymer Dispersion Treatment Employing Hypochlorite Salts or Nitrite Salts to Reduce Fluoropolymer Resin Discoloration - Process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous dispersion medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from said aqueous medium to obtain said fluoropolymer resin. The process comprises:
| 2013-11-14 |
20130303709 | Fluoropolymer Dispersion Treatment Employing High pH and Oxygen Source to Reduce Fluoropolymer Resin Discoloration - Process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous dispersion medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from said aqueous medium to obtain said fluoropolymer resin. The process comprises:
| 2013-11-14 |
20130303710 | Fluoropolymer Dispersion Treatment Employing Hydrogen Peroxide to Reduce Fluoropolymer Resin Discoloration - Process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous dispersion medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from said aqueous medium to obtain said fluoropolymer resin. The process comprises:
| 2013-11-14 |
20130303711 | CHEMICAL MODIFICATION OF LIGNIN AND LIGNIN DERIVATIVES - A method for producing a trans-esterified hydroxypropyl lignin (HPL) is provided in one example embodiment and includes precipitating a lignin, dissolving the precipitated lignin in a solution, adding a reagent to the solution, adjusting the pH of the solution, allowing reactions in the solution to occur for a predetermined amount of time, precipitating the solution to produce a precipitate, and washing, filtering, and drying the precipitate to produce the trans-esterified HPL. | 2013-11-14 |
20130303712 | BRANCHED ADDITIVES FOR POLYMER TOUGHENING - Toughened polymeric materials and methods of forming toughened polymeric materials are provided herein. In some embodiments, a method of forming toughened polymeric materials may include preparing a branched polymeric additive; mixing the branched polymeric additive with a polymer to form a polymeric mixture, wherein the branched polymeric molecule either mixes and/or bonds with the polymer to reduce mobility in the polymer; and curing the polymeric mixture. In some embodiments, a toughened polymeric material comprises a polymer network; and a branched polymeric molecule bonded to the polymer network. | 2013-11-14 |
20130303713 | PROCESS FOR THE PRODUCTION OF METHACRYLIC ACID AND ITS DERIVATIVES AND POLYMERS PRODUCED THEREFROM - A process for the production of methacrylic acid is described. The process comprises the base catalysed decarboxylation of at least one or a mixture of dicarboxylic acids selected from itaconic, citraconic or mesaconic acid. The decarboxylation is carried out in the range greater than 240 and up to 275° C. to provide high selectivity. The methacrylic acid product may be esterified to produce an ester. A method of preparing polymers or copolymers of methacrylic acid or methacrylic acid esters using the process is also described. Optionally, the process may be preceded with a decarboxylation and, if necessary, a dehydration step on a source of pre-acid such as citric acid or isocitric acid. | 2013-11-14 |
20130303714 | BIODEGRADABLE ABSORBENT MATERIAL AND METHOD OF MANUFACTURE - Biodegradable graft copolymers derived from a carbohydrate and at least one α,β-unsaturated carboxylic acid derivative having superabsorbent properties are disclosed in addition to the substantially adiabatic polymerization process by which the graft copolymers are made. The methods disclosed can be carried out in a variety of currently available continuous commercial reactors. Polymerizations carried out with starch have surprisingly produced substantially quantitative yields of graft copolymer free of residual monomer produced as a moist copolymer. Product work-up typically involves an optional neutralization and drying. | 2013-11-14 |
20130303715 | Fluoropolymer Resin Treatment Employing Heating and Oxygen Source to Reduce Discoloration - Process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from said aqueous medium to obtain said fluoropolymer resin. The process comprises:
| 2013-11-14 |
20130303716 | Drying Wet Fluoropolymer Resin and Exposing to Oxygen Source to Reduce Discoloration - Process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous dispersion medium to form aqueous fluoropolymer dispersion and isolating fluoropolymer from said aqueous medium by separating wet fluoropolymer resin from the aqueous medium and drying to produce fluoropolymer resin. The process comprises:
| 2013-11-14 |
20130303717 | Fluoropolymer Dispersion Treatment Employing Oxidizing Agent to Reduce Fluoropolymer Resin Discoloration - A process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous dispersion medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from the aqueous medium to obtain the fluoropolymer resin. The process comprises:
| 2013-11-14 |
20130303718 | Fluoropolymer Dispersion Treatment Employing Oxidizing Agent to Reduce Fluoropolymer Resin Discoloration - A process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous dispersion medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from the aqueous medium to obtain the fluoropolymer resin. The process comprises:
| 2013-11-14 |
20130303719 | SYNTHESIS OF METHYLENE MALONATES SUBSTANTIALLY FREE OF IMPURITIES - The present invention provides improved methods for the chemical synthesis of methylene malonates using the Knovenagel synthesis reaction. The method of the invention provides for improved methylene malonates by significantly reducing or eliminating the formation of alternative and/or deleterious side products, significantly reducing or eliminating unwanted consumption of methylene malonates, and significantly reducing or eliminating the degradation of methylene malonates. These advantages result in methylene malonates, which upon recovery, are of higher quality, greater purity, improved yield and possess overall improved performance characteristics (e.g., improved cure speed, retention of cure speed, improved shelf-life and/or stability). | 2013-11-14 |
20130303720 | POLYISOCYANATE POLYADDITION PRODUCTS, A PROCESS FOR PREPARATION THEREOF AND USE THEREOF - The invention relates to polyisocyanate polyaddition products, to a process for preparation thereof and to the use thereof. | 2013-11-14 |
20130303721 | METHOD FOR MANUFACTURING RESIN FOR URETHANE-BASED OPTICAL MATERIAL, RESIN COMPOSITION FOR SAME, AND OPTICAL MATERIAL MANUFACTURED THEREBY - A method of preparing an optical material by polymerizing a resin composition including a thiol group-containing compound and an isocyanate group-containing compound, particularly, a method of preparing a high-quality urethane-based optical material using a universal polyisocyanate compound. According to one aspect, a resin composition including a polythiol compound and a widely available polyisocyanate compound, as main components, and having a moisture content of 300 to 3,000 ppm is template-polymerized to prepare the optical material. A colorless, transparent, and high-quality urethane-based optical material may be efficiently prepared in high yield using a low-cost and widely available isocyanate compound through template-polymerization using a tape while minimizing generation of white tape residues and foaming. | 2013-11-14 |
20130303722 | NOVEL SUSTAINED RELEASE POLYMER - A polymer and a method for its preparation are provided. The polymer comprises poly(lactide), poly(lactide/glycolide) or poly(lactic acid/glycolic acid) segments bonded by ester linkages to both ends of an alkanediol core unit. The polymer is for use in a controlled release formulation for a medicament, preferably leuprolide acetate. The controlled release formulation is administered to a patient as a subcutaneous depot of a flowable composition comprising the polymer, a biocompatible solvent, and the medicament. Controlled release formulations comprising the polymer release leuprolide for treatment of prostate cancer patients over periods of 3-6 months. | 2013-11-14 |
20130303723 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID - The invention provides a non-naturally occurring microbial organism having a 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in the respective 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid pathway. The invention additionally provides a method for producing 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid. The method can include culturing a 6-aminocaproic acid, caprolactam or hexametheylenediamine producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding a 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid pathway enzyme in a sufficient amount to produce the respective product, under conditions and for a sufficient period of time to produce 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid. | 2013-11-14 |
20130303724 | POLYCARBONATE POLYOL COMPOSITIONS - The present invention provides polycarbonate polyol compositions with improved characteristics. Such polycarbonate polyol compositions are useful in thermosetting applications for the production of coatings for consumer products. The present invention provides compositions having such improved characteristics, in particular, polycarbonate polyol compositions having a glass transition temperature (Tg) from about −20° C. to about 60° C., from about −20° C. to about 50° C., or from about 0° C. to about 30° C., are particularl useful in thermosetting applications. In some embodiments, polycarbonate polyol compositions have a Tg from about −20° C. to about 3° C. In some embodiments, polycarbonate polyol compositions have a Tg from about 0° C. to about 50° C., from about 0° C. to about 50° C., or from about 10 “C. to about 40° C. | 2013-11-14 |
20130303725 | Quaternized Polyethylenimines with a High Quaternization Degree - The present invention relates to an ethoxylated polyethylenimine polymer consisting essentially of (a) a polyethyleneimine backbone, (b) a polyoxyethylene chain wherein the polyoxyethylene chain has an average of 1 to less than 40 ethyleneoxide units per unit of NH in the polyethyleneimine backbone, (3) a quaternization degree of from 50% to 100%. | 2013-11-14 |
20130303726 | METHOD FOR THE PREPARATION OF SURFACTANT PEPTIDES - Surfactant-protein C peptides (SP-C peptides) may be prepared by the heterologous expression of a fusion protein of an SP-C peptide and a maltose binding protein. | 2013-11-14 |
20130303727 | VANCOMYCIN B HYDROCHLORIDE CRYSTALLINE FORM 1 - Vancomycin B Hydrochloride Crystalline Form 1, compositions containing it and methods of prevention or treatment of bacterial infections using it are disclosed. | 2013-11-14 |
20130303728 | LIGAND AND METAL COMPLEX HAVING THE SAME - A ligand and a metal complex having the ligand are provided. The ligand and a paramagnetic metal ion form a metal complex with high stability, high relaxivity and high biocompatibility. The metal complex of the present invention is applicable to the preparation of MRI contrast agents for detecting atherosclerosis. The MRI contrast agent includes a peptide sequence specific to a matrix metalloprotease, and can be recognized by a pathological thrombocyte to target a specific site, so as to enhance the imaging contrast. | 2013-11-14 |
20130303729 | Plasmon-assisted Pyrolysis for Site-specific Protein Digestion - Apparatus using gold nano-particle surface Plasmon resonance heating for a rapid, reagentless and site specific cleavage at the C-terminal of aspartic acid and at the N-terminus of the amino acid cysteine in peptides and proteins induced by the thermal decomposition at 220-250° C. for 10 s in solid samples. | 2013-11-14 |
20130303730 | ASTRINGENCY IN SOY PROTEIN SOLUTIONS - A soy protein product having reduced astringency, which may be an isolate, produces transparent heat-stable solutions at low pH values and is useful for the fortification of soft drinks and sports drinks without precipitation of protein. The soy protein product is obtained by extracting a soy protein source material with an aqueous calcium salt solution to form an aqueous soy protein solution, separating the aqueous soy protein solution from residual soy protein source, adjusting the pH of the aqueous soy protein solution to a pH of about 1.5 to about 4.4 using at least one organic acid, such as citric acid or a blend of citric acid and malic acid or a mixture of at least one organic acid and at least one mineral acid, such as hydrochloric acid and phosphoric acid, to produce an acidified clear soy protein solution, which may be dried directly or following optional concentration and diafiltration, to provide the soy protein product. | 2013-11-14 |
20130303731 | MANUFACTURE OF FACTOR H (FH) AND FH-DERIVATIVES FROM PLASMA - The present invention provides compositions and pharmaceutical formulations of Factor H derived from plasma. Also provided are methods for the manufacture of the Factor H compositions and formulations, as well as methods for the treatment of diseases associated with Factor H dysfunction. | 2013-11-14 |
20130303732 | METHOD FOR USING LIGHT SCATTERING IN REAL TIME TO DIRECTLY MONITOR AND CONTROL IMPURITY REMOVAL IN PURIFICATION PROCESSES - The invention provides a method for controlling contaminants in biopharmaceutical purification processes by using light scattering and UV absorbance to establish a determinant. The invention makes use of multi-angle light scattering (MALS) and UV as a continuous monitoring system to provide information about the elution peak fractions in real-time instead of conventional pooling methods that rely on a predetermined percent UV peak max value to initiate the pooling process; regardless of product quality. | 2013-11-14 |
20130303733 | Multispecific Antibody Targeting and Multivalency Through Modular Recognition Domains - Antibodies containing one or more modular recognition domains (MRDs) that can be used to target the antibodies to specific sites are described. The use of antibodies containing one or more modular recognition domains to treat disease, and methods of making antibodies containing one or more modular recognition domains are also described. | 2013-11-14 |
20130303734 | NOVEL HOMOGENEOUS HUMANIZED ANTIPROLIFERATION ANTIBODIES - The present disclosure relates to novel humanized antibodies able to inhibit tumor growth, as well as the amino and nucleic acid sequences coding for such antibodies. From one aspect, the disclosure relates to novel anti-JAM-A homogeneous humanized antibodies able to inhibit tumor growth. The disclosure also comprises the use of such antibodies as a drug for the preventive and/or therapeutic treatment of cancers, as well as compositions comprising such antibodies in combination with other anticancer compounds. The disclosure also relates to a method for the preparation of such novel humanized antibodies. | 2013-11-14 |
20130303735 | METHOD OF TREATING A PATHOLOGICAL SYNDROME AND A PHARMACEUTICAL AGENT - A method of treating a pathological syndrome includes administration of an activated form of ultra-low doses of antibodies to an antigen, wherein said activated form is obtained by repeated consecutive dilution combined with external impact, and the antigen is a substance or a pharmaceutical agent exerting influence upon the mechanisms of formation of this particular pathological syndrome. | 2013-11-14 |
20130303736 | METHOD FOR MASS PREPARATION OF PROTEOGLYCAN - An object of the present invention is to efficiently extract proteoglycan from aquatic animal tissues. The method of the present invention is a method for extracting proteoglycan from fish cartilage, comprising the step of (A) heating small pieces of frozen fish cartilage in water. This method of the present invention enables easy extraction of proteoglycan from fish cartilage with very high efficiency. In particular, the method of the present invention enables extraction of high-molecular-weight proteoglycan. Further, since in the method of the present invention, extraction is performed using only water, it ensures safety in the extraction and safety of the resulting proteoglycan product, compared with hitherto known extraction methods using organic solvents or acids/alkali. Furthermore, the cumbersome step of removing organic solvents is not necessary in the method of the present invention. | 2013-11-14 |
20130303737 | TARGETED SCHIFF BASE COMPLEXES - The present invention provides targeted Schiff base complexes. In particular the present invention provides biopolymer targeted transition metal complexes configured to inhibit the activity of targeted proteins, methods of synthesis thereof, and pharmaceutical compositions and uses thereof. | 2013-11-14 |
20130303738 | CHEMICAL MODIFICATION OF LIGNIN AND LIGNIN DERIVATIVES - A method for producing an APL is provided in one example embodiment and includes mixing a solvent, a catalyst, a reagent, and a HPL to create a solution, raising the temperature of the solution to a first reaction temperature, raising the temperature of the solution to a second reaction temperature, allowing reactions in the solution to occur for a predetermined amount of time, precipitating the solution to produce a precipitate, and washing, filtering, and drying the precipitate to produce the APL. | 2013-11-14 |
20130303739 | PREPARATION OF LANTHANIDE-CONTAINING PRECURSORS AND DEPOSITION OF LANTHANIDE-CONTAINING FILMS - Methods and compositions for depositing rare earth metal-containing layers are described herein. In general, the disclosed methods deposit the precursor compounds comprising rare earth-containing compounds using deposition methods such as chemical vapor deposition or atomic layer deposition. The disclosed precursor compounds include a cyclopentadienyl ligand having at least one aliphatic group as a substituent and an amidine ligand. | 2013-11-14 |
20130303740 | METHOD FOR PRODUCING URETHANES - The invention relates to a method for producing urethanes or ureas or mixtures of urethanes and ureas by oxidative carbonylation of organic amines in the presence of carbon monoxide, oxygen and a catalyst, where the catalyst used is a transition metal complex containing the structural feature: [Mn+(O˜N˜O)2−](n-2)+(L)m(Z−)n-2 and the method is carried out under halogen-free reaction conditions. The invention further relates to transition metal complexes containing said structural feature and also to the use of such transition metal complexes as catalysts in the production of urethanes or ureas or mixtures of urethanes and ureas. | 2013-11-14 |
20130303741 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE AMINES - The present invention relates to an improved process for the preparation of (R)-1-aminoindan (2), rasagiline (1) and pharmaceutically acceptable salts of rasagiline. | 2013-11-14 |
20130303742 | MIXED SUPER CRITICAL FLUID HYDROLYSIS AND ALCOHOLYSIS OF CELLULOSE TO FORM GLUCOSE AND GLUCOSE DERIVATIVES - The present invention relates to a process for generating glucose and glucose derivatives from the direct contacting of cellulose, hemicelluloses and/or polysaccharides with a mixed super critical fluid system of alcohol and water whereby the partial pressure of the system provides for both alcoholysis and hydrolysis of the material to generate primarily glucose, and glucose derivatives. | 2013-11-14 |
20130303743 | NOVEL 3,6-ANHYDRO-L-GALACTOSE DEHYDROGENASE ACTING ON 3,6-ANHYDRO-L-GALACTOSE, AND PRODUCTION OF 3,6-ANHYDROGALACTONIC ACID BY USING THE ENZYME - The present invention relates to a novel 3,6-anhydro-L-galactose dehydrogenase and to a novel compound produced therefrom. More specifically, provided is a 3,6-anhydro-L-galactose dehydrogenase which can produce 3,6-anhydrogalactonic acid of a novel type by metabolizing 3,6-anhydro-L-galactose. | 2013-11-14 |
20130303744 | USP2A PEPTIDES AND ANTIBODIES - The invention relates to novel USP2a peptides and antibodies, as well as nucleic acids related to them. The peptides, antibodies and the nucleic acids are useful for the detection, staging and monitoring of the progression of cancer, as well as for determining or monitoring the efficacy of treatment. | 2013-11-14 |
20130303745 | Synthesis of oligonucleotides - A method for preparing an oligonucleotide comprising the steps of synthesizing a phosphoramidite by reacting a hydroxyl-containing compound of formula (A) with a phosphitylating agent in the presence of an activator compound of formula (I), to prepare a phosphitylated compound, then coupling the phosphitylated compound without isolation with a second compound having the formula (A), wherein R | 2013-11-14 |
20130303746 | BUFFER FOR ONE-STEP DNA EXTRACTION - DNA is extracted from epithelial cells and other cells without cell walls, by use of a DNA extraction buffer that contains a C | 2013-11-14 |
20130303747 | PYRIMIDINE NUCLEOSIDE DERIVATIVES, SYNTHESIS METHODS AND USES THEREOF FOR PREPARING ANTI-TUMOR AND ANTI-VIRUS MEDICAMENTS - The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, and preparation methods and uses thereof. The structural formula is as shown (I). These compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value. | 2013-11-14 |
20130303748 | METHOD FOR MAKING ALDEHYDE-FUNCTIONALIZED POLYSACCHARIDES - A method for making aldehyde-functionalized polysaccharides having pendant aldehyde groups is described. The method involves the hydroformylation of an alkene-functionalized polysaccharide. The resulting aldehyde-functionalized polysaccharides are useful for forming hydrogel tissue adhesives and sealants for medical applications. | 2013-11-14 |
20130303749 | METHOD AND A SYSTEM FOR PRODUCING NANOCELLULOSE, AND NANOCELLULOSE - A method and system for producing nanocellulose are provided. Cellulose is refined by a first refiner, the refined cellulose is separated by a first separator in such a manner that at least part of it belongs to an accepted fraction, water is removed from the accepted fraction by a precipitator and the accepted fraction is refined by a second refiner to produce nanocellulose. | 2013-11-14 |
20130303750 | METHODS FOR INTEGRATING THE PRODUCTION OF CELLULOSE NANOFIBRILS WITH THE PRODUCTION OF CELLULOSE NANOCRYSTALS - Methods for integrating the production of cellulose nanocrystals (CNC) and cellulose nanofibrils (CNF) from cellulose are provided. The methods use milder acid hydrolysis conditions than those for maximal CNC production to achieve reduced degradation of cellulose into soluble sugars. Also provided are negatively charged cellulosic solid residues (CSRs) in the form of cellulose fibers (CF) and/or cellulose microfibrils (CMF) during the acid hydrolysis, as well as CNFs fabricated from the CSRs. | 2013-11-14 |
20130303751 | Treatment of Wood Pieces - A one or two step process for the acetylation and refining of wood pieces in which acetylation and refining to a reduced geometry take place simultaneously in the refiner. Engineered board products comprising acetylated reduced geometry materials possess high dimensional stability and durability compared to like board products comprising non-acetylated materials. | 2013-11-14 |
20130303752 | MULTI-STAGE PROCESS FOR PRODUCTION OF IMMUNE MODULATOR - Immune function of an animal can be modulated by administration of a composition that includes algae meal or beta glucan. The algae meal can be made by growing | 2013-11-14 |
20130303753 | PREPARATION METHOD OF ROCURONIUM - A method for preparing rocuronium is disclosed. 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstan-3α-ol-17β-acetate is used as a starting material and is directly reacted with 3-bromopropene at ambient temperature to produce rocuronium. | 2013-11-14 |
20130303754 | REFINING PROCESS OF CEFAMANDOLE SODIUM - It discloses a novel process for refining cefamandole nafate, comprising: 1) adsorbing cefamandole nafate with strongly acidic ion exchange resin, followed by eluting the resin and collecting the eluate, to provide a primary purified cefamandole acid after concentration under reduced pressure; 2) neutralizing the primary purified cefamandole acid with an aqueous solution of sodium hydroxide or an aqueous solution of basic salt of sodium, followed by adjusting the pH value and filtrating out the insoluble substances with heating, thereby providing a secondary purified aqueous solution of cefamandole nafate; and 3) adding ethanol in a volume ratio between ethanol and water of 4:6 into the aqueous solution, to allow recrystallization under controlling the temperature, to provide a tertiary purified cefamandole nafate. The refined cefamandole nafate product has a purity of no less than 99.5%, mostly no less than 99.6%, with significantly low content of heavy metals. | 2013-11-14 |
20130303755 | AMINODIHYDROTHIAZINE DERIVATIVES - A composition having BACE 1 inhibitory activity containing a compound represented by the general formula (I): | 2013-11-14 |
20130303756 | METHODS AND COMPOSITIONS FOR PREPARING NORIBOGAINE FROM VOACANGINE - Disclosed are methods and compositions for preparing and purifying the non-addictive alkaloid noribogaine. | 2013-11-14 |
20130303757 | POLYMER PRECURSORS OF RADIOLABELED COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME - One aspect of the present invention relates to novel compounds that can be used to prepare radiolabeled compounds in an effective manner. A second aspect of the present invention relates to a method of synthesizing radiolabeled compounds. | 2013-11-14 |
20130303758 | PREPARATION OF POLYISOCYANATES HAVING ISOCYANURATE GROUPS AND THEIR USE - The present invention relates to a novel process for preparing polyisocyanates having isocyanurate groups by a partial trimerization of (cyclo)aliphatic diisocyanates in the presence of at least one trimerization catalyst from the group of ammonium salts of lactames and to the use of the thus obtainable polyisocyanates having isocyanurate groups as a polyisocyanate component in polyurethane coatings. | 2013-11-14 |
20130303759 | PHOTOCHEMICAL CROSSLINKERS FOR POLYMER COATINGS AND SUBSTRATE TIE-LAYER - The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments. | 2013-11-14 |
20130303760 | New Process For The Preparation Of Nitroorotic Acid - Subject of the present invention is a new improved process for the preparation of nitroorotic acid via nitration of orotic acid. | 2013-11-14 |
20130303761 | COMPOUNDS AS MODULATORS OF A MUTANT CFTR PROTEIN AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH CFTR PROTEIN MALFUNCTION - The present invention relates to novel protein modulators capable of altering function of the mutant CFTR protein and their use for treating diseases associated with CFTR protein malfunction. The invention provides compositions, pharmaceutical preparations and methods of correcting the cellular alteration of a mutant CFTR protein wherein the CFTR mutation is a mutation AF508-CFTR, or another mutation of class II. | 2013-11-14 |
20130303762 | PROCESS FOR PREPARING BOSENTAN - The present invention relates to an improved process for preparing Bosentan of formula (I). | 2013-11-14 |
20130303763 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NECROTIZING ENTEROCOLITIS - This invention relates to tryptophan hydroxylase inhibitors, compositions comprising them, and methods of their use for the treatment, management and/or prevention of necrotizing enterocolitis. | 2013-11-14 |
20130303764 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 2013-11-14 |
20130303765 | PHENYLSILYL PHOSPHINE COMPOUND AND IRIDIUM COMPLEX MADE FROM THE SAME - There are provided a phenylsilyl phosphine compound of formula (I) and an iridium complex of formula (II): | 2013-11-14 |
20130303766 | Organic-Inorganic Hybrid Mesoporous Silica Material Modified by Sulfonic Acid Group for Selective Adsorption of Metal Ions and Method of Manufacturing the Same - A silica precursor having a selective adsorptivity with respect to cobalt ions is disclosed. The silica precursor includes a cross-linked 2,6-diamino pyridine group obtained by using 2,6-diamino pyridine, phosgene and 3-aminopropyltriethoxysilane. | 2013-11-14 |
20130303767 | THIONATING AGENT - A process for transforming a group >C═O (I) in a compound into a group >C═S (II) or into a tautomeric form of group (II) in a reaction giving a thionated reaction product, by use of crystalline P | 2013-11-14 |
20130303768 | METHOD AND SUBSTANCES FOR PREPARATION OF N-SUBSTITUTED PYRIDINIUM COMPOUNDS - A method for the synthesis of N-substituted 3-acylated pyridinium compounds by reacting a pentamethine precursor with a primary amine. | 2013-11-14 |
20130303769 | SEPARATION OF NANOPARTICLES - This invention is directed to separation, optimization and purification of nano-materials using self-assembled perylene diimide membranes, wherein said perylene diimide membrane is recyclable. | 2013-11-14 |
20130303770 | RADIOLABELLED PHENYLIMIDAZOLE-BASED LIGANDS - The present invention relates to radiolabelled PDE10A ligands which are useful for imaging and quantifying the PDE10A enzyme using positron emission tomography (PET). | 2013-11-14 |
20130303771 | PROCESS FOR PREPARING CYCLIC AMINE COMPOUNDS - A cyclic amine compound having a prescribed configuration can be efficiently prepared by reducing an imine derivative in the presence of a sulfonic acid. Specifically, a cyclic amine compound which is substituted with an amino group and a carboxyl group in which both groups are arranged in the trans configuration can be prepared efficiently. | 2013-11-14 |
20130303772 | CRYSTALLINE S-OMEPRAZOLE STRONTIUM HYDRATE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME - Disclosed are a crystalline S-omeprazole strontium hydrate for the prevention or treatment of gastric acid-related diseases, which has high optical purity, thermostability, solubility and nonhygroscopicity, a method for preparing same, and a pharmaceutical composition containing same. | 2013-11-14 |
20130303773 | Rosuvastatin and Atorvastatin Derivatives - This invention relates to the discovery of novel rosuvastatin and atorvastatin analogues. | 2013-11-14 |
20130303774 | Method For Producing Beta-Fluoroalcohol - A production method of a β-fluoroalcohol includes performing a reaction of an α-fluoroester with hydrogen gas (H | 2013-11-14 |
20130303775 | PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL - A process of production of an aromatic alcohol or a heterocyclic aromatic alcohol, containing a step of reacting an aromatic amine or a heterocyclic aromatic amine having an aromatic ring or a heterocyclic aromatic ring having thereon at least one substituent —CHR | 2013-11-14 |
20130303776 | LUMINESCENT MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT, WAVELENGTH-CONVERTING LIGHT-EMITTING ELEMENT, LIGHT-CONVERTING LIGHT-EMITTING ELEMENT, ORGANIC LASER DIODE LIGHT-EMITTING ELEMENT, DYE LASER, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAME - A luminescent material includes transition metal complex comprising a ligand in which an electron density of a p orbital of a highest occupied molecular orbital level is higher than 0.239 and lower than 0.711 when the electron density is calculated according to quantum chemical calculation (Gaussian09/DFT/RB3LYP/6-31G), the p orbital being in the outermost shell of an element coordinated to the metal. | 2013-11-14 |
20130303777 | LUMINESCENT MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT, WAVELENGTH-CONVERTING LIGHT-EMITTING ELEMENT, LIGHT-CONVERTING LIGHT-EMITTING ELEMENT, ORGANIC LASER DIODE LIGHT-EMITTING ELEMENT, DYE LASER, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAME - A luminescent material includes a transition metal complex which comprises any one of Ir, Os, and Pt as a central metal; and at least one of a carbene ligand and a silylene ligand. The carbene ligand includes a boron atom in a skeleton thereof. The carbene ligand is neutral or monoanionic. The carbene ligand is monodentate, bidentate, or tridentate. The silylene ligand includes a boron atom in a skeleton thereof. The silylene ligand is neutral or monoanionic. The silylene ligand is monodentate, bidentate, or tridentate. | 2013-11-14 |
20130303778 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS - Phosphoramidate alkylator prodrugs can be used to treat cancer when administered alone or in combination with one or more anti-neoplastic agents. | 2013-11-14 |
20130303779 | PROCESS FOR THE PREPARATION OF DIOL SULFONES - The present invention relates to a process for the preparation of a diol sulfone derivative comprising reaction of a halomethyl substrate with a thio-aryl compound to obtain a thio-ether compound, and oxidizing the thio-ether compound to the corresponding sulfone. In case of a chiral halomethyl substrate, the resulting chiral diol sulfone derivative is suitable as a building block for statin type compounds. | 2013-11-14 |
20130303780 | PROCESS FOR THE PREPARATION OF 2-ARYLTHIAZOLE DERIVATIVES - The present invention relates an improved process for the preparation of 2-arylthiazole derivatives which are intermediates of Febuxostat and further conversion to Febuxostat or pharmaceutically acceptable salts thereof. | 2013-11-14 |
20130303781 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE - The present invention discloses a method for preparing Triclabendazole comprising condensing N-(4,5-dichloro-2-ni-trophenyl)acetamide with 2,3-dichlorophenol to obtain 4-chloro-5(2,3-dichlorophenoxy)-2-nitrophenyl acetamide and it to obtain 4-chloro-5(2,3-dichlorophenoxy)-2-nitroaniline; reducing 4-chloro-5(2,3-dichlorophenoxy)-2-nitroaniline in presence of Raney nickel to obtain 4-chloro-5-(2,3-dichlorophenoxy)benzene-1,2-diamine of; cyclising 4-chloro-5-(2,3-dichlorophenoxy)benzene-1,2-diamine in presence of carbondisulfide to obtain 6-chloro-5-(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol; methylating 6-chloro-5-(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol using a methylating agent to obtain triclabendazole methanesulfonate salt; converting triclabendazole methanesulfonate salt to hydrochloride salt of Triclabendazole and hydrolysing it to obtain Triclabendazole. | 2013-11-14 |
20130303782 | PROCESS FOR PREPARATION OF ALBENDAZOLE - The present invention discloses a novel, cost-effective process for preparation of a benzimidazole carbamates compound. Specifically, it relates to the process for the preparation of anti-parasite bulk drug albendazole. The process comprises a) thiocyanating 2-nitroaniline of formula VI with ammonium thiocyanated in presence of a halogen to obtain 2-nitro-4-thiocyanoaniline of formula V; b)propylating 2-nitro-4-thiocyanoaniline of formula V with propylbromide in presence of n-propanol and a base in absence of a phase transfer catalyst to obtain 4-propylthio-2-nitroaniline of formula III; C) reducing the nitro group of 4-propylthio-2-nitroaniline prepared in step b) by reacting an aqueous alkali metal sulphide or an alkaline metal sulphide to obtain 4-propylthio-o-phenylenediamine of formula II; and d)condensing 4-propylthio-o-phenylenediamine of formula II with alkali or alkaline earth metal salt of methylcyano carbamate in presence of an acid to form Albendazole of formula I. | 2013-11-14 |
20130303783 | DEVICE AND PROCESS FOR CONTINUOUS PHOSGENATION - A continuous process for generation of phosgene from CO and Cl | 2013-11-14 |
20130303784 | METHOD FOR PREPARING AMINOETHYL IMIDAZOLIDINONE AND THE THIOCARBONYL THEREOF - The present invention relates to a method for preparing 1-(2-aminoethyl)imidazolidin-2-one or the thiocarbonyl thereof, and also to the product that can be obtained according to this method, and which has a purity of at least 98%, and to the uses thereof. | 2013-11-14 |
20130303785 | CRYSTALLINE, COMPLETELY SOLUBLE LITHIUM BIS(OXALATO)BORATE (LiBOB) - A crystalline, completely soluble lithium bis(oxalato)horate (LiBOB), to a method for producing the same and to the use of the lithium bis(oxalato)borate. | 2013-11-14 |
20130303786 | BENZYLPIPERIZINE COMPOUND - Disclosed is a benzylpiperizine compound represented by formula (1) or a pharmaceutically acceptable salt thereof, which is useful as a medicinal agent such as an antidepressant agent. (In the formula (1), R | 2013-11-14 |
20130303787 | Process For Preparing Alditol Acetals - A process for preparing alditol Acetals via a dehydrocondensation reaction is disclosed. The reaction is carried out by adding an aldehyde and an aldiol using a metal salt based ionic liquid as an acid catalyst. The ionic liquid used in the process is prepared by dissolving a hydrogen donor and a compound providing counter ion in a solvent. | 2013-11-14 |
20130303788 | METHOD OF PRODUCING BIPHENOLIC COMPOUND, NOVEL BIPHENYL COMPOUND AND SYNTHESIS METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING PARKINSON'S DISEASE - A method of producing honokiol and analogues thereof, and novel intermediates prepared by virtue thereof are disclosed herein. A pharmaceutical composition for treating Parkinson's disease, which contains honokiol and/or the analogues thereof, is also disclosed herein. | 2013-11-14 |
20130303789 | TRIOXOLANE AND RELATED STABILIZED OXYGEN MOLECULES BASED TREATMENT PRODUCT - A treatment product including trioxolanes or related stabilized oxygen molecules. Just as oxidation is a somewhat violent electron transfer that results in amino acid malformation, only a molecule with similar electron attraction potential, another oxygen species in the form of a stabilized trioxolane or equivalent, can reverse such damage in most cases. The human body has the ability to fix such oxidation on its own, but this ability declines with age and excess damage. The treatment product described herein including trioxolanes, assists the body in this natural process. The result is reduction of inflammation, aging, and other conditions of the human body. | 2013-11-14 |
20130303790 | Pseudopolymorphic Forms Of A HIV Protease Inhibitor - New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed. | 2013-11-14 |
20130303791 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES - Described herein are single step methods of making various classes of alkylamine derivatives of furan and tetrahydrofuran by simultaneous contact of a sugar with H | 2013-11-14 |
20130303792 | PROCESS FOR PREPARING FUEL COMPOSITIONS - A process for the preparation of a ring-hydrogenated alkyl furfuryl ether of the general formula (I) or a mixture of such ethers: (I) R″-TF—CH2-O—R where TF represents a 2,5-disubstituted tetrahydrofuran ring, where each R independently represents a hydrocarbyl group having from 1 to 20 carbon atoms and where each R″ independently represents a methyl group, a hydroxymethyl group, the product of an aldol condensation reaction or an alkoxymethyl group of the general formula (II): (II) —CH2-O—R′ where each R′ independently represents a hydrocarbyl group having from 1 to 20 carbon atoms, the process including the step of reacting a 5-(alkoxymethyl)furfural of the general formula (III) or a 2,5-bis(dialkoxymethyl)furan of the general formula (IV) under hydrogenation conditions: (III) R′−O—CH2-F—CH═O (IV) R′—O—CH2-F—CH2-O—R″ to form said ring-hydrogenated alkyl furfuryl ether of the general formula (I) or a mixture of said ethers wherein F represents a 2,5-disubstituted furan ring, and R′, and R″ have the definitions as described above. | 2013-11-14 |
20130303793 | Process for the manufacture of 1,2-epoxy-3-chloropropane - Process for the manufacture of 1,2-epoxy-3-chloropropane by reaction between allyl chloride and hydrogen peroxide in the presence of a solid catalyst and in the possible presence of at least one solvent in an epoxidation medium comprising at least two liquid phases under the conditions of reaction, wherein the catalyst exhibits an external surface to volume ratio lower than to 2.4 10 | 2013-11-14 |
20130303794 | EXTRACTION OF SOLUTE FROM SOLUTE-BEARING MATERIAL - This invention is directed to a process for separating a solute from a solute-bearing material. A substantial amount of solute is extracted from the solute-bearing material by contacting particles of the solute-bearing material with globules of an extraction solvent. The particle size of the solute-bearing material and the globule size of the extraction solvent are balanced such that little if any solute or extraction solvent remains in the solute-bearing material. | 2013-11-14 |
20130303795 | METHOD OF MAKING FATTY ACID N-ACYLALKANOLAMINES - The present invention relates to methods for making a fatty acid N-acylalkanolamine having the formula: | 2013-11-14 |
20130303796 | METHOD FOR CONTINUOUSLY PREPARING CARBOXYLIC ACID ESTER - A method for continuously preparing a carboxylic acid ester is disclosed. In the method of the present invention, a vertical reactor is filled with a solid catalyst, a carboxylic acid and an alcohol are introduced into a lower part of the vertical reactor, esterification is performed to form an esterized mixture, the esterized mixture is output from an upper part of the vertical reactor, and distillation is performed to isolate the carboxylic acid ester. The method of the present invention is simple, easily controlled and environmental friendly, and has significantly high conversion rate and selectivity. | 2013-11-14 |
20130303797 | METHOD FOR SYNTHESIZING 2-CYANO-3,12-DIOXOOLEAN-1, 9(11)-DIEN-28-OIC ACID METHYL ESTER AND DERIVATIVES THEREOF - The present invention is a method for preparing triterpenoids such as 2-cyano-3,12-dioxoolean-1,9-dien-28-methyl ester and derivatives thereof from oleanic acid, ursolic acid, betulinic acid, sumaresinolic acid or hederagenin. | 2013-11-14 |
20130303798 | PROCESS FOR SYNTHESIZING PHENYLACETIC ACID BY CARBONYLATION OF TOLUENE - A production process for substituted phenylacetic acids or ester analogues thereof is disclosed. In this process toluene or toluene substituted with various substituents, an alcohol, an oxidant and carbon monoxide are used as raw materials to obtain compounds comprising structure of phenylacetic acid ester or analogues thereof by catalysis of the complex catalyst formed from transition metal and ligand, and such compounds are hydrolyzed to obtain various substituted phenylacetic acid based compounds. This type of compounds and their derivatives serve as important fine chemicals used widely in the industries of pharmaceuticals, pesticides, perfume and the like. | 2013-11-14 |
20130303799 | PROCESS FOR THE PREPARATION OF POLY(ALKYLENE OXIDE) DERIVATIVES FOR MODIFICATION OF BIOLOGICALLY ACTIVE MOLECULES AND MATERIALS - A a method for producing activated linear polymers and activatable branched polymers thereof, is carried out by a) reacting a linear nonpeptidic activatable polymer, chemically blocked at one end, with an azole ring activating group that provides a leaving group to produce an intermediate polymer of the general formula poly-lm; b) reacting said poly-lm with an alkylating agent to form an imidazolium salt of the general formula poly-1m+(alkyl)X-; and c) reacting said poly-lm +(alkyl)X with a linker molecule bearing at least two nucleophilic moieties to produce an activatable branched polymer derivative thereof. In some embodiments “poly” is a polymer selected from the group consisting of poly(alkylene oxides), poly(oxyethylated polyols), poly(olefinic alcohols), and polymers of alkylene oxide and propylene oxide; in some embodiments “Im +” is an imidazolium ion; and in some embodiments “X-” is an anionic counterion. | 2013-11-14 |
20130303800 | PROCESS FOR PRODUCING ACETIC ACID - A process for stably producing high-purity acetic acid while efficiently removing acetaldehyde is provided. | 2013-11-14 |
20130303801 | Novel Glycerol Dehydration Catalyst and Production Method Therefor - Provided is a novel catalyst that can produce acrolein and acrylic acid in high yields using glycerol as starting material. The disclosed glycerol dehydration catalyst has niobic oxide synthesized by hydrothermal synthesis as the main component. | 2013-11-14 |
20130303802 | USE OF MONASCUS IN ORGANIC ACID PRODUCTION - The present invention provides tools and methods for producing organic acids using strains of | 2013-11-14 |
20130303803 | METHOD FOR PURIFYING A CHLORINE SUPPLY - This invention provides a method for purifying a chlorine supply that includes a chlorine component, a bromine component, and nitrogen trichloride. The method includes the steps of introducing the chlorine supply into a vaporizer, heating the chlorine supply in the vaporizer to form a vapor, and introducing the vapor into a distillation system to provide purified chlorine gas, a distillate that includes liquid chlorine and the bromine component, and a bottoms component including the nitrogen trichloride. The method also includes the steps of condensing the vapor in a reflux condenser, heating the condensate in a reboiler, removing the purified chlorine gas from the distillation system, and removing the distillate from the distillation system. | 2013-11-14 |
20130303804 | Process For Preparing A Thixotroping Agent And Use Thereof - The invention provides a process for preparing a thixotropic agent based on a urea derivative, in which the components α) comprising at least one amine and β) comprising at least one isocyanate, are supplied separately to a mixing means and are mixed with one another, the reaction mixture being discharged by spraying or squirting from the mixing means. Further disclosed is the use of the thixotropic agent in a fluid system. The process is especially suitable for preparing adhesives and sealants. | 2013-11-14 |
20130303805 | PRODUCTION METHOD FOR AMINO COMPOUND - The present invention relates to a process for producing an amino compound by subjecting a polyamine and an alkenyl compound to addition reaction in the presence of an alkali metal hydride compound which is capable of supplying the amino compound in a stable manner without occurrence of odor. | 2013-11-14 |
20130303806 | METHOD FOR PURIFICATION OF MIXTURES COMPRISING MTBE AS WELL AS PRODUCTION OF ISOBUTENE BY SPLITTING OF MIXTURES COMPRISING MTBE - The present invention relates to a process for efficient purification of MTBE-containing mixtures and for preparation of isobutene by cracking of MTBE-containing mixtures. | 2013-11-14 |
20130303807 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES - The present invention provides a process for purifying a monoterpene or sesquiterpene having a purity greater than about 98.5% (w/w). The process comprises the steps of derivatizing the monoterpene (or sesquiterpene) to produce a monoterpene (or sesquiterpene) derivative, separating the monoterpene (or sesquiterpene) derivative, and releasing the monoterpene (or sesquiterpene) from the derivative. Also encompassed by the scope of the present invention is a pharmaceutical composition comprising a monoterpene (or sesquiterpene) having a purity greater than about 98.5% (w/w). The purified monoterpene can be used to treat a disease such as cancer. The present monoterpene (or sesquiterpene) may be administered alone, or may be co-administered with radiation or other therapeutic agents, such as chemotherapeutic agents. | 2013-11-14 |