39th week of 2013 patent applcation highlights part 56 |
Patent application number | Title | Published |
20130252783 | POWERTRAIN SYSTEM FOR HYBRID VEHICLES HAVING COMPOUND AND SPLIT MODES OF OPERATION - A powertrain system for a vehicle is provided, including an internal combustion engine, a drivetrain gear for connection to a drivetrain of the vehicle, a gearset connecting the internal combustion engine to the drivetrain gear, a first electric machine connected to the gearset, a second electric machine, and at least one dynamic clutch selectively coupling the second electric machine to the drivetrain gear and the gearset. In a compound mode of operation, the at least one dynamic clutch couples the second electric machine and the gearset. In a split mode of operation, the at least one dynamic clutch couples the second electric machine and the drivetrain gear. | 2013-09-26 |
20130252784 | FAILSAFE DEVICE FOR SHIFT-BY-WIRE SYSTEM - There is provided a failsafe device for a shift-by-wire system, including: a parking range operation unit with which a diver inputs a request to shift to a parking range; a control unit that changes the state of an automatic transmission to a parking range state in response to the shift request from the parking range operation unit; a failure determination unit that determines whether or not the actual state of the automatic transmission is the parking range state; and a brake device that brakes wheels of a vehicle with an actuator. The control unit brakes the wheels with the brake device when the failure determination unit determines that the actual state of the automatic transmission is not the parking range state after the request to shift to the parking range has been issued from the parking range operation unit. | 2013-09-26 |
20130252785 | SHIFT-BY-WIRE CONTROL SYSTEM - There is provided a shift-by-wire control system including a range switching device that switches engagement or disengagement of a forward engagement element and a reverse engagement element by using an actuator, a range switching operation unit by which a driver inputs a range switching operation, and a range switching control unit that controls the actuator of the range switching device on the basis of the state of the range switching operation unit. The shift-by-wire control system further includes vehicle start preparation state determination units for determining a vehicle start preparation state. When the vehicle start preparation state determination unit determines that the vehicle start preparation state is incomplete, the range switching control unit executes running prohibition control by which the forward engagement element and the reverse engagement element are all disengaged, regardless of the state of the range switching operation unit. | 2013-09-26 |
20130252786 | EXERCISE MACHINE - An exercise machine equipped with a device designed to be driven to move by the user during a workout, by applying a muscular force against a resistant load and which includes: a detector for detecting the muscular power applied by the user to the device; a display; a computer connected to the display and having access to a memory containing a plurality of values, representative of the power nominally absorbed by a plurality of corresponding electric household appliances, and digital data for graphically representing the plurality of electric household appliances, the computer being programmed for: comparing the power detected by the detector and at least one of the power values contained in the memory; and for generating on the display, depending on the comparison, a graphical output of the comparison, including a graphical representation of at least one of the electric household appliances, generated based on the digital data. | 2013-09-26 |
20130252787 | Trampoline angle suspension apparatus - The invention is a wakeboard training device utilizing a trampoline for the jumping surface and a tow rope structure for the control for the rider. The jumping surface can be inclined to improve simulating wave support and the trampoline improves safety and training efficiency. A training park would include connecting four of these devices together to form a quadrangle shape to maximize room efficiency so that multiple riders can train safely in a room including allowing one rider to perform tricks for 360 degrees about the pivot center of the devices. | 2013-09-26 |
20130252788 | STARTING BLOCK - An adjustable swimmer's starting block includes a wedge shaped launch block that is movable between a stowed position and plural positions along a surface of a starting platform, providing adjustable positioning to the starting block for adaptation to different users and uses. | 2013-09-26 |
20130252789 | WEIGHTED EXERCISE BAR - A weighted exercise bar has an elongate housing with an inner cavity extending between a first end and a second end of the elongate housing. There is an access opening to the inner cavity, and three or more elongate elements are removably disposed in the inner cavity. There is at least one weighted element adjacent to the first end or the second end and at least one spacer element. A combined length of the elongate elements is substantially the same as a length of the inner cavity. | 2013-09-26 |
20130252790 | UPPER BODY EXERCISE DEVICE - An upper body exercise device includes a central tube supported at a first height by at least two legs. A pair of wings is hingedly connected to the central tube. Each wing includes a pair of parallel arcuate rails, each rail having an outer end opposite the central tube, and each rail having a nadir at a second height lower than the first height. A hand slider is slidably supported on top of the pair of parallel arcuate rails of each of the pair of wings. Each hand slider includes a grip and a friction mitigation unit connected to the grip. Each hand slider is slidable along the pair of parallel arcuate rails between the central tube and the outer ends of the pair of parallel arcuate rails. The wings can be rotated about the central tube between an exercise configuration and a storage configuration. | 2013-09-26 |
20130252791 | EXTREMITY SUPPORTING AND GROUND SURFACE SLIDING EXERCISE SYSTEM - An extremity supporting exercise system is described. The system includes two knee sliders and two hand sliders. Each knee slider includes a knee pad and a knee base. The knee pad includes a recessed portion that is adapted to receive a user's knee. A patella support is disposed within the knee portion to support the user's patella when using the knee slider. Alternatively, each hand slider includes a hand pad and a hand base. The hand pad includes a series of finger indentations that are flanked by thumb receptacles. Importantly, the knee base and hand base are formed of a rigid and slippery material to allow the sliders to easily slide across a ground surface. Thus, through use of the exercise system, a user can support their hands and knees while sliding the hands and knees across a ground surface to perform a variety of exercises. | 2013-09-26 |
20130252792 | SURFBOARD REPLICATING BALANCE BOARD SYSTEM - A balance board adapted for riding rail-to-rail, preferably so that at least a portion of a rider's feet will be placed on the board over the elongated tube. The balance board includes an elongated, planar board having a length that exceeds a width. The balance board further includes two pair of stops mounted to an underside of the board, each pair of stops being mounted near opposite ends of the board, and each stop of the pair of stops being mounted near opposite sides of the board. The balance board further includes a traction region between each stop of each pair of stop. | 2013-09-26 |
20130252793 | ROTATING PART FOR IMAGE FORMING APPARATUS, CARTRIDGE FOR FORMING IMAGE, AND IMAGE FORMING APPARATUS - A rotating part for an image forming apparatus, including: a drive member; and a driven member, wherein either of the drive member and the driven member has a male part formed in the direction of a rotational shaft, wherein the other of the drive member and the driven member has a female part formed in the direction of the rotational shaft, and wherein the male part is a ratchet-shape male part to be inserted into the female part and in which when the drive member rotates in a first direction, the male part is brought into engagement with the female part to thereby transmit power from the drive member to the driven member, while when the drive member rotates in a second direction opposite to the first direction, the male part and the female part move away from each other to thereby transmit no power. | 2013-09-26 |
20130252794 | WINDING MACHINE AND WINDING METHOD - A winding machine ( | 2013-09-26 |
20130252795 | Folding Machine - A folding machine for folding a stack of sheets, the folding machine comprising: a frame; means for pre-folding a stack of sheets along a crease line into a main plane such that a booklet with a straight back is obtained; means for keeping the pre-folded booklet relative to the frame; means for finishing the fold; and a transport plate having a leading edge around which the stack of sheets is folded, said transport plate being movable along the means for pre-folding and the means for finishing the fold. | 2013-09-26 |
20130252796 | DEVICE FOR INSERTION INTO A ROTOR OF A CENTRIFUGE, CENTRIFUGE AND METHOD FOR THE FLUIDIC COUPLING OF CAVITIES - A device for insertion into a rotor of a centrifuge has at least two bodies stacked one above the other in a stacking direction inside a housing. The housing is configured such that it can be inserted into a holder of the rotor of the centrifuge. With a correct reception of the device in the centrifuge, and upon a rotation of the rotor, a spacing of one of the at least two bodies in relation to the axis of rotation of the rotor is smaller than a spacing of another of the at least two bodies in relation to the axis of rotation of the rotor. A first of the at least two bodies has at least one first cavity and a second cavity and a second body of the at least two bodies has at least one first cavity. The two bodies are movably disposed in relation to each other inside the housing in order to fluidically couple, in a first phase, responding to a rotation of the rotor, the first cavity of the first body to the first cavity of the second body and to fluidically couple in a second phase the second cavity of the first body to the first cavity of the second body. | 2013-09-26 |
20130252797 | CRYSTAL GLASS HAVING REFRACTIVE INDEX HIGHER THAN 1.53 WITHOUT A CONTENT OF COMPOUNDS OF LEAD, BARIUM AND ARSENIC - This invention relates to a crystal glass having a refractive index higher than 1.53 and a high mechanical strength, free of any content of compounds of lead, barium and arsenic and guaranteeing maximum safety for health, which consists in that it comprises by weight: 55-70% SiO | 2013-09-26 |
20130252798 | METALLIC SULFIDE PHOTOCATALYST FOR CARBON DIOXIDE REDUCTION AND THE PREPARATION FOR THE SAME - Disclosed are the metallic sulfide photocatalyst and its preparation method. The photocatalyst includes at least one soluble metallic salt and a sulfide with the oxidation state of S atom ≦+4. The photocatalyst is afforded by reacting the sulfide with the at least one soluble metallic salt dissolved in the complexing agent. Additionally, the photocatalyst further is customized with co-catalyst such as RuCl to form Ru-carried metallic sulfide photocatalyst. The metallic sulfide photocatalyst and Ru-carried metallic sulfide photocatalyst are capable of effectively reducing CO | 2013-09-26 |
20130252799 | MTO REGENERATOR MULTI-PASS GRIDS - A process and device for the regeneration of catalyst is presented. The device includes a series of grids within a regeneration vessel, where each grid includes small openings for the passage of gas, and larger openings for the passage of catalyst. The grids span horizontally across the vessel, and are spaced vertically apart to create a flow of catalyst down through the regenerator. | 2013-09-26 |
20130252800 | ROBUSTNESS OF COKE BURNING FROM CATALYST FOR LIGHT PARAFFIN DEHYDROGENATION PROCESS - A process for a continuous regeneration of a catalyst wherein the regeneration section includes at least two separate zones. The regeneration includes an upper combustion zone, and an lower combustion zone, where the process utilizes at least two independent regeneration gas loops for control of the amount of oxygen to regenerate the catalyst. The upper combustion zone can be divided into multiple zones, and the combustion zone can be divided into multiple zones. | 2013-09-26 |
20130252801 | PROCESS FOR MANAGING SULFUR ON CATALYST IN A LIGHT PARAFFIN DEHYDROGENATION PROCESS - A process is presented for the management of sulfur on a catalyst. The catalyst is a dehydrogenation catalyst, and sulfur accumulates during the dehydrogenation process. Sulfur compounds are stripped from the spent catalyst and the catalyst is cooled before the regeneration process. The process includes controlling the amount of sulfur that needs to be removed from the catalyst before regeneration. | 2013-09-26 |
20130252802 | IN-SITU PRODUCED Y-FAUJASITE FROM KAOLIN-DERIVED, PRE-SHAPED PARTICLES AND THE METHOD OF PREPARATION AND TEH USE THEREOF - A zeolite-containing fixed bed catalyst is formed by pre-shaping a mixture of a reactive aluminum-containing component and a matrix component into pre-shaped particles, and contacting the pre-shaped particles with a reactive liquid containing a silicate for a sufficient time and temperature to form an in-situ zeolite within the pre-shaped particles. The contacting of the pre-shaped particles and the liquid is achieved such that there is relative movement between the pre-shaped particles and the liquid. | 2013-09-26 |
20130252803 | PROCESS AND APPARATUS FOR MIXING TWO STREAMS OF CATALYST - A process and apparatus for mixing streams of regenerated and carbonized catalyst utilizes a ramp or bend provided on only one of the catalyst conduits to provide mixing advantages. | 2013-09-26 |
20130252804 | OLEFIN ISOMERIZATION AND METATHESIS CATALYST - A process for the production of propylene, the process including: contacting ethylene and a hydrocarbon stream comprising 1-butene and 2-butene with a bifunctional isomerization-metathesis catalyst to concurrently isomerizes 1-butene to 2-butene and to form a metathesis product comprising propylene; wherein the bifunctional isomerization-metathesis catalyst comprises: a catalyst compound may include at least one element selected from tungsten, tantalum, niobium, molybdenum, nickel, palladium, osmium, iridium, rhodium, vanadium, ruthenium, and rhenium for providing metathesis activity on a support comprising at least one element from Group IA, IIA, IIB, and IIIA of the Periodic Table of the Elements; wherein an exposed surface area of the support provides both isomerization activity for the isomerization of 1-butene to 2-butene; and reactive sites for the adsorption of catalyst compound poisons. In other embodiments, the catalyst compound may include at least one element selected from aluminum, gallium, iridium, iron, molybdenum, nickel, niobium, osmium, palladium, phosphorus, rhenium, rhodium, ruthenium, tantalum, titanium, tungsten, and vanadium. | 2013-09-26 |
20130252805 | PROCESS AND APPARATUS FOR MIXING TWO STREAMS OF CATALYST - A process and apparatus for mixing streams of regenerated and carbonized catalyst involves passing a catalyst stream around an insert in a lower section of a riser. The insert fosters mixing of the catalyst streams to reduce their temperature differential before contacting hydrocarbon feed. | 2013-09-26 |
20130252806 | Ag/MnyOx/C CATALYST, PREPARATION AND APPLICATION THEREOF | 2013-09-26 |
20130252807 | SULFUR-RESISTANT CATALYST SUPPORT MATERIAL - A catalyst support material and a catalyst system incorporating said support material along with a method of making the same is provided for use in applications in which the support material is exposed to sulfur-containing impurities. The catalyst support material generally comprises an inorganic oxide base material having a surface and pores of predetermined size; and a zirconium layer adapted to interact with the surface and sized to be received by the pores of the base material. The catalyst support material being prepared by applying a layer of a zirconium compound to the surface and pores of an inorganic oxide base material followed by calcination in order to convert the zirconium compound to a metal, a metal oxide, or a mixture thereof. | 2013-09-26 |
20130252808 | CATALYSTS FOR THERMOCHEMICAL FUEL PRODUCTION AND METHOD OF PRODUCING FUEL USING THERMOCHEMICAL FUEL PRODUCTION - To provide a catalyst, which is formed from a perovskite oxide, for thermochemical fuel production, and a method of producing fuel using thermochemical fuel production that is capable of allowing a fuel to be produced in a thermochemical manner. | 2013-09-26 |
20130252809 | METHOD FOR ACTIVATION OF CHROMIUM CONTAINING CATALYST PRECURSOR FOR POLYMERIZATION AND THE RESULTING POLYMERIZATION CATALYST - The instant invention relates to an activation of a polymerization catalyst precursor by heat treatment comprising a support material and a catalyst precursor deposited thereon in a fluidized bed activator and to the use of the activated polymerization catalyst in the manufacture of polyolefins. The activation involves heat treatment in the presence of oxygen. After that activation the oxygen in the activator is replaced by inert gas via flushing until the fluidization gas ermerging from the activator comprises oxygen in a maximum amount of up to 5 ppm. The catalyst prepared by that method is improved with respect to prevent reactor fouling during gas-phase polymerization or slurry polymerization either in stirred vessel or loop. | 2013-09-26 |
20130252810 | PLANT SEED ASSEMBLIES COMPRISING FUNGAL/BACTERIAL ANTAGONISTS - A seed treated with a fungal/bacterial antagonist combination and a seed assembly comprising a seed and a fungal/bacterial antagonist combination. The fungal/bacterial antagonist combination comprises a | 2013-09-26 |
20130252811 | NOVEL HERBICIDE - Herbicidal composition comprising a pyrandione herbicide and a co-herbicide The present invention relates to a herbicidal composition comprising as active ingredient a mixture of a) a herbicidally effective amount of a compound of formula (I) wherein: R | 2013-09-26 |
20130252812 | TANKMIX ADDITIVE CONCENTRATES CONTAINING TRIGLYCERIDE Fatty Acid ESTERS AND METHODS OF USE - Tankmix additive concentrates containing a phosphate ester and/or polymeric surfactant and a triglyceride fatty acid ester and the use of aqueous herbicide spray mixtures incorporating such tankmix additive concentrates are described. The tankmix additive concentrates described herein include from 1 to 50 weight percent of a phosphate ester surfactant, a polymeric surfactant, or mixtures thereof, and from 1 to 90 weight percent of a triglyceride fatty acid ester. The tankmix additive concentrates form a stable emulsion upon dilution into a pesticide spray mixture. | 2013-09-26 |
20130252813 | Herbicidal Compositions for Tolerant or Resistant Sugar Beet Crops - Herbicide combinations (A)+(B), with an effective content of
| 2013-09-26 |
20130252814 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM AND PRETILACHLOR - Provided herein are herbicidal compositions containing (a) penoxsulam and (b) pretilachlor providing synergistic weed control. | 2013-09-26 |
20130252815 | ROSEOBACTICIDES AND USES THEREOF - Embodiments of the invention relate to compounds and methods for controlling algal growth, for example, in bodies of water or surfaces exposed to algae. Provided are compounds having algicidal activities and methods of use of these compounds as well as formulations and compositions comprising the compound having algicidal activities. | 2013-09-26 |
20130252816 | HERBICIDAL COMPOSITION AND USE THEREOF - The present invention relates to the use of a branched-chain alcohol ethoxylate adjuvant as a rapid visual indicator of a locus of herbicidal treatment. In particular the invention includes novel herbicidal compositions comprising glyphosate and such an adjuvant, as well as the use of such compositions in combating unwanted plant growth. Compositions of the invention not only exhibit rapid symptomology, but also provide long-lasting control of unwanted plant growth across a broad spectrum of plants. | 2013-09-26 |
20130252817 | AQUEOUS HERBICIDE CONCENTRATES CONTAINING FATTY ACID ALKYL ESTERS, FATTY ACID AMIDES, OR TRIGLYCERIDE FATTY ACID ESTERS AND METHODS OF USE - Aqueous herbicide concentrates containing a herbicide (such as an auxinic herbicide), a surfactant, and a fatty acid alkyl ester, a fatty acid amide, and/or a triglyceride fatty acid ester and the use of aqueous herbicide spray mixtures incorporating such concentrates are described. The aqueous herbicide concentrates described herein include from 5 to 90 weight percent of a water soluble salt of a herbicide, from 0.1 to 20 weight percent of a surfactant, and from 0.1 to 20 weight percent of a fatty acid alkyl ester, fatty acid amide, and/or a triglyceride fatty acid ester. The aqueous herbicide concentrate is a transparent, homogeneous liquid that forms a stable emulsion upon dilution into a spray solution. | 2013-09-26 |
20130252818 | AMORPHOUS BIOINORGANIC IONIC LIQUID COMPOSITIONS COMPRISING AGRICULTURAL SUBSTANCES - An amorphous formulation of a herbicidal or pesticidal substance includes a composition of the formula [A] | 2013-09-26 |
20130252819 | CRYO-MAGNETIC MOTOR - A cryo-magnetic motor is described. The motor includes a magnetic rotor having a first portion and a second portion. The motor can also include a stator assembly having an insulated casing, a liquid chamber, and a superconducting plate. | 2013-09-26 |
20130252820 | Method of Manufacturing High-Frequency Acceleration Cavity Component - According to one embodiment, there is provided a method of manufacturing a high-frequency acceleration cavity component, the method including covering a mold with a conducting material, enclosing, in an outer shell, the mold covered with the conducting material, vacuum-airtight-welding the outer shell enclosing the mold, conducing hot isostatic pressing of the vacuum-airtight-welded outer shell, and taking the conducting material formed in the mold out of the outer shell which has undergone the hot isostatic pressing. | 2013-09-26 |
20130252821 | METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF DISEASES CHARACTERIZED BY VASCULAR LEAK, HYPOTENSION, OR A PROCOAGULANT STATE - Disclosed herein are methods for treating a vascular leak disorder, hypotension, or a procoagulant state using angiopoietin-2 (Ang-2) antagonist compounds. Also disclosed are methods for treating a vascular leak disorder associated with high dose IL-2 therapy using angiopoietin-2 antagonist compounds. Methods for diagnosing and monitoring vascular leak disorders, hypotension, or a procoagulant state that include the measurement of Ang-2 polypeptide or nucleic acid levels are also disclosed. Methods for inducing a vascular leak using an Ang-2 agonist are also disclosed. | 2013-09-26 |
20130252822 | Methods for Predicting an Antibody Response to Interferon Therapy in Multiple Sclerosis Patients - The present invention relates to a method of diagnosing a predisposition of a multiple sclerosis patient to become less susceptible or resistant to treatment with interferon β, said method comprising determining in a sample obtained from said patient the presence of one or more SNP(s) selected from the group consisting of SNPs defined by the sequences of SEQ ID NOs 12, 17, 2, 3, 5, 7, 8, 1, 4, 6, 9, 10, 11, 13, 14, 15 and 16, wherein the presence of one or more of said SNP(s) in said sample is indicative for said predisposition. | 2013-09-26 |
20130252823 | cDNA SYNTHESIS USING NON-RANDOM PRIMERS - The present invention provides methods for selectively amplifying a target population of nucleic acid molecules in a population of RNA template molecules (e.g., all mRNA molecules expressed in a cell type except for the most highly expressed mRNA species). The invention also provides a method of generating a population of oligonucleotide primers for transcriptome profiling of total RNA from a subject of interest. | 2013-09-26 |
20130252824 | SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA FROM TARGET INDIVIDUALS USING GENETIC DATA FROM GENETICALLY RELATED INDIVIDUALS - A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed. Genetic data for the target individual is acquired and amplified using known methods, and poorly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related subjects. In accordance with one embodiment of the invention, incomplete genetic data is acquired from embryonic cells, fetal cells, or cell-free fetal DNA isolated from the mother's blood, and the incomplete genetic data is reconstructed using the more complete genetic data from a larger sample diploid cells from one or both parents, with or without genetic data from haploid cells from one or both parents, and/or genetic data taken from other related individuals. | 2013-09-26 |
20130252825 | Signal Enhancement in Molecular Assays - The present invention relates generally to signal enhancement in single-molecule-assays. In particular, the present invention relates to an array allowing signal enhancement of single molecules. The assay is in particular a Bioassay allowing single molecule analysis of biomolecules. Preferably, the signal enhancement is a fluorescence enhancement based on optical antenna. In another aspect, the present invention relates to a method for measuring irradiation of electromagnetic waves of single compounds. Based on the arrays and methods, it is possible to allow signal enhancement and, consequently, allow single molecule assays with high sensitivity and reproducibility. | 2013-09-26 |
20130252826 | LARGE DELETIONS IN HUMAN PMS2 GENE AND USE THEREOF - Large deletions have been identified in the PMS2 gene in patients. The large deletions predispose the patients to Lynch syndrome associated cancers. Thus, methods for detecting the genetic variants are provided which can be used in detecting a predisposition to cancer. | 2013-09-26 |
20130252827 | DETECTION OF TARGET NUCLEIC ACID SEQUENCES USING DUAL-LABELED IMMOBILIZED PROBES ON SOLID PHASE - The present invention relates to a novel method for detection of target nucleic acid sequences on a solid phase using dual-labeled immobilized probes and its resistance to a 5′ to 3′ exonuclease activity of a DNA polymerase. Because the label is remained on the solid substrate by resistance to nucleases due to labeling of a base component the internal nucleotide, the present invention requires no consideration of a suitability of position of the label for remaining on the solid substrate. The present invention ensures to minimize background signal by positioning labels at a site on probes suitable to maximize quenching efficiency of the dual label system, since it permits to freely determine the position of the internal label on probes. | 2013-09-26 |
20130252828 | CHEMICAL SENSING DEVICE - An apparatus with a transducer having a first output signal and arranged to receive an electrical input. The transducer switches the first output signal between an ON and OFF state. The apparatus has a chemical sensing surface coupled to the transducer arranged to receive a chemical input. A signal generator oscillates one or more of said inputs to vary the switching point of the transducer. The oscillating input may be the chemical input and/or the electrical input. The output signal may be a pulse whose period ON or OFF is determined by the oscillating input modulated by the chemical input. | 2013-09-26 |
20130252829 | Parallel Methods For Insertional Mutagenesis - The present invention provides parallel methods for identifying the locations of insertion elements that are distributed at different sites in the genome among a collection of cells. | 2013-09-26 |
20130252830 | ENHANCED GENE EXPRESSION - The present disclosure is directed to a novel, unexpected approach of expressing exogenous gene(s) at increased levels by predictably, optionally irreversibly, incorporating the gene(s) into a region of increased gene expression (RIDGE) on a chromosome of a host cell. This approach is accomplished by identification of RIDGE(s) and further by integration of integrase-specific sites (e.g., attP or attB) in the presence of or mediated by integrase. The approach renders a high level of gene expression; predictability of the location of the exogenous genes, elimination of genetic instability or unwanted phenotype; and reduction of time and cost in optimizing protein production in host cells, which will be every useful in the production of therapeutic, prophylactic, and diagnostic proteins. | 2013-09-26 |
20130252831 | METHOD OF DIAGNOSING EARLY STAGE NON-SMALL CELL LUNG CANCER - A “malignancy-risk” (MR) gene signature score was developed with abundant proliferative genes using principal component analysis. This MR gene signature was shown to be a predictive and prognostic factor of overall survival in early-stage NSCLC. The malignancy-risk signature showed a significant association with OS, with poor survival seen in patients having a higher MR score and better survival seen in patients having a low MR score. As a prognostic factor, the MR gene signature showed a positive correlation with TNM stage, histologic grade, and smoking status. Combination of the MR signature with each clinical parameter often showed the best survival in the low MR group with good clinical outcome. The MR gene profile, tested with a PCA scoring method, discriminated overall survival in lung cancer patients was a predictor independent of pathological staging and other clinical parameters. | 2013-09-26 |
20130252832 | KRAS Variant and Tumor Biology - The disclosure provides methods for identifying a subject at risk of developing cancer, predicting the onset of cancer, and predicting a subject's response to chemotherapy/treatment by determining the presence or absence of a SNP in the KRAS oncogene, known as the KRAS variant. | 2013-09-26 |
20130252833 | DRG11-RESPONSIVE (DRAGON) GENE AND USES THEREOF - This invention features methods and compositions useful for treating and diseases caused by a dysregulation of the BMP/GDF branch of the TGF-β signaling pathway. Also disclosed are methods for identifying compounds useful for such therapy. | 2013-09-26 |
20130252834 | Diagnostic Methods - The invention relates to a method of aiding the diagnosis of acute brain damage in a subject, said method comprising (i) assaying the concentration of at least one oxidative stress polypeptide selected from the group consisting of: PRDX1, PRDX6 and GSTP1 in a sample from said subject; and (ii) assaying the concentration of at least one further polypeptide selected from Panel A; (Hi) comparing the concentrations of (i) and (ii) to the concentrations of the polypeptides in a reference standard and determining quantitative ratios for said polypeptides; (iv) wherein a finding of a quantitative ratio of each of the assayed polypeptides in the sample to the polypeptides in the reference standard of greater than 1.3 indicates an increased likelihood of acute brain damage having occurred in said subject. | 2013-09-26 |
20130252835 | METHODS FOR PROFILING AND QUANTITATING CELL-FREE RNA - The invention generally relates to methods for assessing the health of a tissue by characterizing circulating nucleic acids in a biological sample. According to certain embodiments, methods for assessing the health of a tissue include the steps of detecting a sample level of RNA in a biological sample, comparing the sample level of RNA to a reference level of RNA specific to the tissue, determining whether a difference exists between the sample level and the reference level, and characterizing the tissue as abnormal if a difference is detected. | 2013-09-26 |
20130252836 | DIAGNOSTIC TEST FOR CARDIOMYOPATHY - Methods and compositions relating to diagnosing and treating cardiomyopathy and particularly relating to methods and compositions for diagnosing and treating arrhythmogenic right ventricular dysplasia/cardiomyophathy (ARVD/C) are described. Provided are methods for screening for, diagnosing or detecting a risk of developing arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) comprising detecting the presence of a transmembrane protein 43 (TMEM43) disease associated variant in a sample of a subject, wherein the presence of a TMEM43 disease variant is indicative that the subject has ARVD/C or an increased risk of developing ARVD/C compared to an individual having wild type TMEM43. | 2013-09-26 |
20130252837 | METHOD FOR MEASURING RESISTANCE OR SENSITIVITY TO DOCETAXEL - The present invention relates to novel and useful methods that predict or monitor a patient's response to a molecule of the taxoid family by measuring the increase or decrease of specific genetic markers as compared to controls. The present invention also provides kits that predict of monitor patient's response to a molecule of the taxoid family by measuring nucleic acid or protein levels of particular genetic markers and comparing their levels to controls or reference markers. | 2013-09-26 |
20130252838 | TARGET FOR BREAST CANCER THEREAPY AND/OR DIAGNOSIS - The present invention relates to breast cancer and methods for identifying therapeutics and diagnosis. In general, methods for identifying therapeutic agents directed to calcium flow are disclosed. Also provided are methods for diagnosis of breast cancer and/or a predisposition to breast cancer and methods of treatment of breast cancer. The methods include identifying therapeutic agents which modulate a CRAC channel and/or a glycoprotein activator of a CRAC channel. Also provided are diagnostic methods that utilise a CRAC channel and/or a glycoprotein activator of a CRAC channel. | 2013-09-26 |
20130252839 | MARKERS OF PRIMARY GRAFT DYSFUNCTION - The present invention relates to methods for diagnosing transplant rejection, or a condition associated with transplant rejection, such as, primary graft dysfunction in a subject, to antigen probe arrays for performing such a diagnosis, and to antigen probe sets for generating such arrays. | 2013-09-26 |
20130252840 | LIQUID TISSUE PREPARATION FROM HISTOPATHOLOGICALLY PROCESSED BIOLOGICALLY SAMPLES, TISSUES AND CELLS - The current invention provides a method for directly converting histopathologically processed biological samples, tissues, and cells into a multi-use biomolecule lysate. This method allows for simultaneous extraction, isolation, solublization, and storage of all biomolecules contained within the histopathologically processed biological sample, thereby forming a representative library of said sample. This multi-use biomolecule lysate is dilutable, soluble, capable of being fractionated, and used in any number of subsequent experiments. | 2013-09-26 |
20130252841 | ARRAYED DETECTOR SYSTEM FOR MEASUREMENT OF ANTI-VIRAL IMMUNE RESPONSE - A sensor chip for detecting an immune response against a virus, the sensor chip including a substrate having a surface and a plurality of virus-like particles or capsid fragments bound to discrete locations on the surface of the substrate. Detection devices containing the sensor chip and methods of detecting anti-viral immune responses are also described herein. | 2013-09-26 |
20130252842 | Methine-Substituted Cyanine Dye Compounds - Cyanine dye compounds having a substituted methine moiety that are nucleic acid stains, particularly for fluorescent staining of RNA, including compounds having the formula | 2013-09-26 |
20130252843 | METHOD OF MAKING AND USING FLUORESCENT-TAGGED NANOPARTICLES AND MICROARRAYS - Disclosed embodiments concern differentiating and classifying one or more targets using a perhalophenylazide-derived nanoparticle probe, or multiple such probes. Particular embodiments concern using statistical analysis to produce score plots illustrating the level of differentiation and/or classification. Also disclosed are methods for making perhalophenylazide-derived nanoparticle probes, individually or by using a microarray technique. Particular embodiments concern methods for using the per halophenylazide-derived nanoparticle probes to diagnose, detect, and/or treat a disease. Kits comprising the perhalophenylazide-derived nanoparticle probes are also disclosed. | 2013-09-26 |
20130252844 | SUGARCANE-STALK-SUGAR-CONTENT-RELATED MARKER AND THE USE THEREOF - According to the present invention, a sugarcane-stalk-sugar-content-related marker linked to a sugarcane quantitative trait is provided. Such marker is a sugarcane-stalk-sugar-content-related marker, which comprises a continuous nucleic acid region existing in a region sandwiched between the nucleotide sequence shown in SEQ ID NO: 1 and the nucleotide sequence shown in SEQ ID NO: 8 or a region sandwiched between the nucleotide sequence shown in SEQ ID NO: 9 and the nucleotide sequence shown in SEQ ID NO: 16. | 2013-09-26 |
20130252845 | METHOD FOR SCREENING SKIN AGING-RELATED GENES AND MATERIALS FOR PREVENTING SKIN AGING - The present invention relates to a method for screening skin aging-specific genes and a method for screening anti-aging materials by controlling the expression of the genes. The invention can provide a new material having an effect on the prevention of skin aging and the treatment of skin diseases by obtaining new target genes related to skin aging and controlling the expression of the genes. | 2013-09-26 |
20130252846 | SCREENING METHOD - A method of screening a plurality of fluid samples for the presence of species capable of specifically binding to a binding partner immobilized on a sensing surface of a sensor is disclosed. The method comprises contacting each sample with the sensing surface and a reference surface, and subjecting the sensing surface responses obtained for all samples to a computational process which comprises fitting al responses to a model equation for the relationship between a response at the sensing surface and the corresponding response at the reference surface. In an iterative process residuals above a pre-determined threshold value are removed, the model equation is adjusted, and all remaining samples are refitted to the adjusted model equation until the model equation at least substantially converges. Residuals above the predetermined threshold value are considered as species specifically binding to the binding partner. The method may be computer-implemented, and a computer program product therefore comprises instructions for causing a computer to perform the computational process. | 2013-09-26 |
20130252847 | ASSAY ASSEMBLY AND METHOD - The present invention relates to assay assemblies, components of assay assemblies, methods of determining one or more properties of a sample liquid, and methods of making components of assay assemblies. The present invention allows the properties of very small volumes of sample liquid to be probed, by providing a first surface having at least one sample liquid wettable surface region defined by a sample liquid repelling boundary, and a second surface, opposed to the first surface, having analyte binding agent immobilised thereon. | 2013-09-26 |
20130252848 | CELLOMICS SYSTEM - In labeling a cell, and separating and collecting the cell according to a degree of the labeling using a cell separator, effects on the cell is minimized and the use of the collected cell is facilitated, thereby, when labeling a cell, the cell is labeled in the state where interaction of each cell is retained. In the labeling, a specific labeling material present on a surface of a target cell is taken in the cell via a transporter, and the cell is dispersed one by one to separate the same with a cell separator. Immediately after the separation, the cell is put in a solution not containing the specific labeling substance to remove the specific labeling substance taken in the cell. This series of steps is continuously conducted with a cell separation chip. | 2013-09-26 |
20130252849 | METHODS FOR SCREENING PROTEINS USING DNA ENCODED CHEMICAL LIBRARIES AS TEMPLATES FOR ENZYME CATALYSIS - Disclosed are methods, compositions and devices for screening a protein library for proteins having a desired activity, such as capable of catalyzing the formation of a bond between two reactants. In an exemplary embodiments, a plurality of proteins are expressed in vitro from a plurality of nucleic acids, the plurality of proteins are exposed with two single stranded oligonucleotides having complementary sequences, each oligonucleotide having a reactant and a fluorophore, the fluorescence of the protein-reactant-oligonucleotide-fluorophore complexes is detected and the complexes showing detectable fluorescence energy transfer are isolated, thereby isolating proteins having the desired enzymatic activity. | 2013-09-26 |
20130252850 | Alpha-Amylase Variants - The invention relates to a variant of a parent Termamyl-like alpha-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an alpha-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an alpha-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an alpha-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an alpha-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like alpha-amylase, which variant exhibits increased. | 2013-09-26 |
20130252851 | METHOD OF MAKING A PAIRED TAG LIBRARY FOR NUCLEIC ACID SEQUENCING - The present disclosure relates to methods and compositions for making paired tags and paired tag libraries. | 2013-09-26 |
20130252852 | Oligonucleotides Related to Lipid Membrane Attachment - A method of forming a lipid membrane attached linker comprises contacting a lipid membrane with an oligonucleotide having a first strand and a second strand of nucleic acid and two or more hydrophobic anchoring moieties located in its terminal ends. The two strands are hybridized to each other in a duplex section in a manner that the first strand terminal end is not a part of the duplex section and free from a hydrophobic anchoring moiety and the two or more hydrophobic anchoring moieties are covalently attached to the adjacent terminal ends of the first strand and the second strand of said oligonucleotide, thereby accomplishing a direct attachment of the oligonucleotide by the moieties on the same membrane. | 2013-09-26 |
20130252853 | NOVEL PROCESS FOR DRILLING SUBTERRANEAN CAVITIES - A process for drilling cavities in subterranean formations includes a step of removal of the drill cuttings using an aqueous fluid in the form of a foam, obtained by mixing: an aqueous composition (Ci) including, per 100% by weight: from 0.5% by weight to 25% by weight of a compound of formula (I): R | 2013-09-26 |
20130252854 | OIL DRILLING AUXILIARY DISPERSION - A dispersion liquid for supporting oil drilling, including: an aqueous medium and a particulate solid polyglycolic acid resin dispersed in the aqueous medium; wherein the particulate polyglycolic acid resin has a weight-average molecular weight of at least 70,000 and at most 500,000, and exhibits weight retentivities in water at 80° C. of at least 85% after 12 hours, at most 80% after 72 hours, and at most 45% after 168 hours. The particulate solid polyglycolic acid resin included in the above-mentioned dispersion liquid for supporting oil drilling, functions as a fluidity control material exhibiting ideal degradation characteristics in the drilling operation for expansion of oil production capacity, demanded for suppressing the liquid permeability in the early stage and recovery of the liquid permeability after completion of the operation of the formation around the oil well. | 2013-09-26 |
20130252855 | NOVEL USE OF A MILD ALKALINE AGENT IN CHEMICAL EOR - Aqueous compositions including a mild alkaline agent (i.e. compound of formula (I) or (V)) and a surfactant are provided. The compositions and methods of using the same are particularly useful in the field of enhanced oil recovery. | 2013-09-26 |
20130252856 | SYNERGISTIC SURFACTANT COMPOSITIONS FOR UNLOADING FLUIDS FROM OIL AND GAS WELLS - A method for unloading fluids from an oil and gas well, pipeline or flowline includes using a synergistic combination of an alkyl glucoside and an amphoteric surfactant as a foaming composition. Use of the combination foaming composition improves unloading of formation fluids, particularly production fluids having natural gas condensate and water and therefore increases the rate of production from the oil and gas well. | 2013-09-26 |
20130252857 | COMPLETION FLUID - An aqueous well completion/workover fluid, including a surfactant, at least one salt and an alkaline material, wherein the surfactant comprises a mixture of a phosphate ester and a non ionic ethoxylated alcohol, wherein the fluid has a pH between 6 and 8, and wherein the fluid generates an interfacial tension with crude oil of less than or equal to 1 dyne/cm. The fluid is not harmful to a formation if it penetrates the formation, and further exhibits an excellent detergency which can be beneficial as well. | 2013-09-26 |
20130252858 | Low-Toxicity, Low-Flammability, Environmentally-Safe, Friction Reducer Fluid For Hydraulic Fracturing - Improved hydraulic fracturing compositions are disclosed which help reduce potential negative environmental impact by hydraulic fracturing. The disclosed compositions have flammability and toxicity and are relatively safe for the environment. The compositions may also contain biodegradable components. | 2013-09-26 |
20130252859 | SOLID LUBRICATING, HARD AND FRACTURE RESISTANT COMPOSITES FOR SURFACE ENGINEERING APPLICATIONS - A method and composition for producing a monolithic hybrid composite consisting of a composite matrix, a reinforcement phase, and a solid/self-lubrication phase. The composition may comprise a graphite (“C”) phase and a titanium carbide (“TiC”) phase in a nickel (“Ni”) matrix. The process may include the step of blending pure Ni and pure titanium (“Ti”) powders with Ni-coated graphite powder using Laser Engineered Net Shaping (“LENS”). The novel composite, when achieved with an optimum chemical and structural phase ratio, exhibits a balance of high hardness, fracture toughness, and low friction/wear, | 2013-09-26 |
20130252860 | SLIDING STRUCTURAL MEMBERS - A sliding structural member is provided which achieves a good low frictional property. A DLC film | 2013-09-26 |
20130252861 | LUBRICANT FOR HOT FORGING APPLICATIONS - A substantially lead-free lubricant for use in hot forging of metals, especially forging of aluminum and aluminum alloy components. The lubricant comprises one or more oils, graphite, and one or more phosphorus-based additives. Additional additives, such as metallic lubricants and dispersants may also be included. The lubricant does not burn when subjected to temperatures in excess of 300° C. | 2013-09-26 |
20130252862 | DRY LUBRICANT FOR CONVEYING CONTAINERS - The passage of a container along a conveyor is lubricated by applying to the container or conveyor a mixture of a water-miscible silicone material and a water-miscible lubricant. The mixture can be applied in relatively low amounts, to provide thin, substantially non-dripping lubricating films. In contrast to dilute aqueous lubricants, the lubricants of the invention provide drier lubrication of the conveyors and containers, a cleaner conveyor line and reduced lubricant usage, thereby reducing waste, cleanup and disposal problems. | 2013-09-26 |
20130252863 | NOVEL ANTIOXIDANT COMBINATION AND SYNTHETIC BASE OILS CONTAINING THE SAME - Disclosed are compositions of a major amount of alkylated aromatics compounds, in particular alkylated naphthalene and alkylated benzene, optionally combined with API Group II, Group III, Group IV and/or ethylene copolymers, showing improved thermo-oxidation performance when containing an additive combination including an alkylated or non-alkylated diarylamine and a sulfur-containing metal passivator. Particularly, the lubricating compositions include at least 55 wt % of a base oil selected from the group consisting of alkylated naphthalene, alkylated benzene and combinations thereof, and from 0 wt % to 45 wt % of another base oil component. The ratio of amine component to sulfur component in the additive combination is from 1:1 to 20:1. The compositions contain an amount of base oil other than alkylated naphthalene, alkylated benzene and API Group II, Group III, Group IV and/or ethylene copolymers of less than 10 wt % based on the total weight of the components comprising the lubricating composition. | 2013-09-26 |
20130252864 | Preparation of Phosphorus - Containing Antiwear Compounds for Use in Lubricant Compositions - A process is provided for preparing a salt of a hydroxy-substituted ester of phosphoric acid, comprising: (a) reacting a phosphate diester with an alkylene oxide, (b) reacting the product mixture of step (a) with a phosphating agent; and (c) reacting the product mixture of step (b) with an amine; wherein the phosphate diester is reacted with the alkylene oxide of step (a) in the substantial absence of a phosphate monoester. The product is useful as an antiwear agent. | 2013-09-26 |
20130252865 | LUBRICATING OIL COMPOSITIONS - A lubricating oil composition comprising a major amount of oil of lubricating viscosity and a minor amount of one or more compounds of formula (I): | 2013-09-26 |
20130252866 | COPOLYMERS COMPRISING ESTER GROUPS AND USE THEREOF IN LUBRICANTS - The present invention relates to copolymers comprising ester groups and having at least one nonpolar segment P and at least one polar segment D, the polar segment D having at least 8 repeat units and the proportion by weight of dispersing repeat units in the polar segment D being at least 30%, based on the weight of the polar segment D, wherein the copolymer comprising ester groups is obtainable by NMP (nitroxide mediated polymerization). The invention further relates to lubricant oils having improved friction properties and comprising said copolymers. | 2013-09-26 |
20130252867 | Monitoring Cleaning of Surfaces - A method for monitoring cleaning of a surface includes applying an amount of transparent indicator material to an area of a surface and measuring the amount of transparent indicator material remaining on the surface. The transparent indicator material may be fixed on the surface by drying and, when a fluorescent material, may be measured through exposure to ultraviolet radiation. | 2013-09-26 |
20130252868 | LIQUID CLEANING AND DISINFECTING COMPOSITIONS - The present invention relates to a liquid cleaning and disinfecting composition and, in one embodiment, a liquid cleaning and disinfecting liquid hand dishwashing composition, comprising an alkyl or substituted alkyl branched alkyl chain amine oxide. | 2013-09-26 |
20130252869 | CLEANING COMPOSITIONS COMPRISING PH-SWITCHABLE AMINE SURFACTANTS - A cleaning composition may comprise a pH-switchable sudsing system and a cleansing system. The pH-switchable sudsing system may comprise a primary sudsing agent in combination with a pH-switchable co-surfactant. The pH-switchable co-surfactant is selected from diamine molecules having a general formula R | 2013-09-26 |
20130252870 | CLEANING COMPOSITION INCLUDING A TERPOLYMER CONTAINING MALEIC ACID, VINYL ACETATE, AND ALKYL ACRYLATE MONOMERS FOR ENHANCED SCALE CONTROL - The present invention is related to a cleaning composition including at least one alkalinity source and a biodegradable terpolymer including maleic acid, vinyl acetate and alkyl acrylate segments or monomers for controlling scale. The diluted use solution has a pH between about 7 and about 11.5. | 2013-09-26 |
20130252871 | CLEANING COMPOSITION INCLUDING A TERPOLYMER CONTAINING MALEIC ACID, VINYL ACETATE, AND ALKYL ACRYLATE MONOMERS FOR ENHANCED SCALE CONTROL - The present invention is related to a cleaning composition including at least one alkalinity source and a biodegradable terpolymer including maleic acid, vinyl acetate and alkyl acrylate segments or monomers for controlling scale. The diluted for use solution has a pH range of between about 9.5 and about 14. | 2013-09-26 |
20130252872 | TERPOLYMER CONTAINING MALEIC ACID, VINYL ACETATE, AND ALKYL ACRYLATE MONOMERS FOR ALUMINUM PROTECTION - A cleaning composition includes an alkali metal silicate, a polymer including maleic acid, vinyl acetate and alkyl acrylate monomers, and optionally water. The cleaning composition can include approximately 10% and approximately 90% by weight of at least one alkali metal silicate, greater than or equal to approximately 0.1% by weight of the polymer containing maleic acid, vinyl acetate and alkyl acrylate monomers, and approximately 0% to approximately 80% by weight water. | 2013-09-26 |
20130252873 | METHOD FOR REDUCED ENCRUSTATION OF TEXTILES USING A POLYMER COMPRISING MALEIC ACID, VINYL ACETATE, AND ALKYL ACRYLATE - A laundry detergent composition includes an alkalinity source, at least one nonionic surfactant and a polymer comprising maleic acid, vinyl acetate and alkyl acrylate monomers. The alkalinity source is present in an amount between about 1% and about 75% by weight of the laundry detergent composition and includes at least one member selected from alkali metal hydroxides, carbonates, and bicarbonates. The polymer comprising maleic acid, vinyl acetate and alkyl acrylate monomers is present in an amount equal to or greater than about 0.5% by weight of the laundry detergent composition. | 2013-09-26 |
20130252874 | DETERGENT COMPOSITIONS COMPRISING GRAFT POLYMERS HAVING BROAD POLARITY DISTRIBUTIONS - The present invention relates to a detergent composition containing an amphiphilic graft polymer based on water-soluble polyalkylene oxides (A) as a graft base and side chains formed by polymerization of a vinyl ester component (B), where the polymer has a broad polarity distribution. | 2013-09-26 |
20130252875 | Thickener Systems For Personal Care and Other Cleansing Compositions - Disclosed herein are liquid personal care cleansing compositions comprising a carrier (e.g., aqueous), a detergent surfactant for personal cleansing (i.e., hair, skin, or nails), and a thickening system that may include components that are naturally-derived and naturally-processed. The thickening system includes a gum, a lactate, and a lactylate, and is substantially free of synthetic amides such as ethanolamines. The lactate and lactylate have surprisingly been found to break the gelatinous, gooey blob characteristics that result when thickening with a natural gum alone, resulting in a homogenous smooth consistency to the personal care composition thickened with the thickener system. | 2013-09-26 |
20130252876 | COMPOSITIONS AND METHOD FOR PROMOTING MUSCULOSKELETAL REPAIR - A method of treating a musculoskeletal injury in a subject includes administering directly to a site of the musculoskeletal injury or to an area proximate the musculoskeletal injury an amount of SDF-1, MCP-3, or combinations thereof effective to promote repair of the musculoskeletal injury of the subject and recruit connective tissue progenitor cells to the site of the musculoskeletal injury. | 2013-09-26 |
20130252877 | METHOD FOR PREPARING ACTIVE PEPTIDES FROM CORN GERM PROTEINS - The present invention discloses a method for producing antihypertensive active peptides with corn germ protein as the material. The method comprises an alkali-heat treatment and continuous enzymolysis of the corn germ protein. The components with molecular weight less than 1000 Da in the active peptides obtained according to the present method account for more than 92%, and alanine-tyrosine (Ala-Tyr, AY) as the characteristic peptide fragments in the antihypertensive peptides accounts for more than 0.6%, so that the active peptides have a good ACE inhibitory activity in vitro as well as stability against temperature, pH and major gastrointestinal digestive enzymes, and have a significant effect of lowering blood pressure on spontaneous hypertension rats in vivo. The active peptides can be applied as a new functional nutrient to development and production of food, health food and pharmaceutical. | 2013-09-26 |
20130252878 | COMPOSITION CONTAINING PEPTIDE LIGAND THAT BONDS WITH CXCR2 FOR TREATING INFECTIVE AND INFLAMMATORY DISEASES - A therapeutic agent for treating an infectious or inflammatory disease, a pharmaceutical composition for treating an infectious or inflammatory disease, and a method of using a pharmaceutical composition are provided. The pharmaceutical composition includes a peptide ligand that binds with CXCR2 as an active component. The active component can be useful in preventing and treating infectious and/or inflammatory diseases, including sepsis and septic shock by promoting the removal of bacteria by phagocytosis, suppressing an inflammatory response, and suppressing the apoptosis of immune cells. | 2013-09-26 |
20130252879 | RAPAMYCIN FORMULATION USING RECOMBINANT HIGH-DENSITY LIPOPROTEIN INCLUDING APOLIPOPROTEIN A-I AND A MUTANT THEREOF - Provided is a rapamycin formulation using a recombinant high-density lipoprotein including apolipoprotein mutant, the rapamycin formulation in which solubility of rapamycin and medical use, such as aging suppression and arteriosclerosis suppression, are improved by using recombinant high-density lipoprotein including apolipoprotein A-I and its mutant V156K. | 2013-09-26 |
20130252880 | Dendrimeric Peptides, Pharmaceutical Compositions And Methods Of Using The same - Novel dendrimeric peptide compounds are disclosed that have a formula represented by the following formula I: | 2013-09-26 |
20130252881 | Transcription Factor Decoys - Decoy nucleic acid sequences comprising a sequence encoding all or part of a binding site for bacterial sigN alternative sigma54 factor are described. Uses of the decoys in antibacterial complexes and for the treatment of bacterial infections are also described. | 2013-09-26 |
20130252882 | ANTIMICROBIAL 4-OXOQUINOLIZINES - This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In addition the novel 4-oxoquinolizine compounds are useful against CDC Category A and B pathogens The invention also provides pharmaceutical compositions comprising certain 4-oxoquinolizines in combination with subinhibitory concentrations of polymyxin B against clinical isolates which are resistant to quinolones, carbapenems and other antimicrobial agents. | 2013-09-26 |