38th week of 2014 patent applcation highlights part 127 |
Patent application number | Title | Published |
20140271878 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF - The subject invention provides a mixture of crystalline laquinimod sodium particles, wherein (i) 90% or more of the total amount by volume of the laquinimod sodium particles have a size of 40 microns or less or (ii) 50% or more of the total amount by volume of the laquinimod sodium particles have a size of 15 microns or less, and wherein:
| 2014-09-18 |
20140271879 | FINE DRY PARTICULATE RETINOID ACTIVE AGENT COMPOSITIONS AND TOPICAL FORMULATIONS INCLUDING THE SAME - Fine dry particulate retinoid compositions suitable for use in topical formulations, as well as methods of making the same, are provided. In the dry particulate retinoid compositions, the retinoid active agent is associated with the particles, e.g., via entrapment in the pores of the particles and/or ionic binding and/or non-covalent binding to the surface of the particles and/or loosely associated with the particles. Also provided are topical formulations which include the dry particulate retinoid compositions of the invention, and methods of using the same. | 2014-09-18 |
20140271880 | FINE DRY PARTICULATE RESVERATROL ACTIVE AGENT COMPOSITIONS AND TOPICAL FORMULATIONS INCLUDING THE SAME - Fine dry particulate resveratrol compositions suitable for use in topical formulations, as well as methods of making the same, are provided. In the dry particulate resveratrol composition, the resveratrol active agent is associated with the particles, e.g., via entrapment in the pores of the particles and/or ionic binding and/or non-covalent binding to the surface of the particles and/or loosely associated with the particles. Also provided are topical formulations which include the dry particulate resveratrol compositions of the invention, and methods of using the same. | 2014-09-18 |
20140271881 | ANTISEPTIC COMPOSITION - The invention relates to an antiseptic composition. The composition comprises an association of at least silver metal, preferably in a micronised form, and hyaluronic acid or one of the salts thereof having a molecular weight of between 50 kDa and 2000 kDa. The invention can be especially applied to the field of veterinary medicine, for the treatment of skin wounds and the healing thereof. | 2014-09-18 |
20140271882 | 17-HYDROXYPROGESTERONE ESTER CONTAINING ORAL COMPOSITIONS AND RELATED METHODS - The present invention provides for bioavailable oral dosage forms containing esters of 17-hydroxyprogesterone as well as related methods. The oral dosage forms can be formulated for pregnancy support and can include a therapeutically effective amount of an ester of 17-hydroxyprogesterone and a pharmaceutically acceptable carrier. In another embodiment, a pharmaceutically acceptable oral dosage form for pregnancy support is provided. The pharmaceutically acceptable oral dosage can include a therapeutically effective amount of an ester of 17-hydroxyprogesterone and a pharmaceutically acceptable carrier. The oral dosage form can, when measured using a USP Type-II dissolution apparatus in 900 mL of deionized water with 0.5 (w/v) of sodium lauryl sulfate at 50 RPM at 37° C., release at least 20 wt % of the dose of the ester of 17-hydroxyprogesterone after 60 minutes, or in the alternative release at least 20 wt % more after 60 minutes than an equivalently dosed oral dosage form without the carrier. | 2014-09-18 |
20140271883 | CURCUMINOIDS AND METABOLITES THEREOF FOR TREATING ALLERGIC NASAL CONDITIONS - A pharmaceutical composition for nasal administration comprising: a nanoemulsified curcumin component; a liquid medium for the curcumin component; and a pharmaceutically acceptable excipient. The curcumin component is a natural curcuminoid, a synthetic curcuminoid, a metabolite of a natural or synthetic curcuminoid, or a mixture thereof. The excipient is effective in increasing the bioavailability of the curcumin component. | 2014-09-18 |
20140271884 | HIGH-LOADING NANOPARTICLE-BASED FORMULATION FOR WATER-INSOLUBLE STEROIDS - Compositions comprising water-insoluble steroids encapsulated into nanoparticle forms are provided. Methods of preparing water-insoluble steroids encapsulated in a nanoparticle form are provided. Methods of treating disease by delivering a water-insoluble steroid encapsulated into nanoparticle form to a patient in need thereof are provided. | 2014-09-18 |
20140271885 | COPOLYMERS FOR STABLE MICELLE FORMULATIONS - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications. | 2014-09-18 |
20140271886 | Bioerodible Silicon-Based Compositions for Delivery of Therapeutic Agents - The invention comprises a composition comprising a bioerodible porous silicon-based carrier material wherein the carrier material carries at least one large molecule therapeutic agent and at least one amorphous sugar, optionally further comprising a crystallization inhibitor. The composition may be used in vitro or in vivo to deliver the therapeutic agent, preferably in a controlled fashion over an intended period of time such as over multiple days, weeks or months. The composition may be used for treating or preventing conditions of a patient such as chronic diseases. | 2014-09-18 |
20140271887 | ANTIEMETIC EXTENDED RELEASE SOLID DOSAGE FORMS - A solid oral dosage form includes a core comprising a non-ionic polymer matrix, a first amount of a first antiemetic drug or a pharmaceutically acceptable salt thereof dispersed within the matrix, and a salt dispersed within the matrix; a first seal coat of a non-ionic polymer matrix surrounding the core; and an immediate release drug layer surrounding the first seal coat, wherein the immediate release drug layer comprises a non-ionic polymer and a second amount of a second antiemetic drug or a pharmaceutically acceptable salt thereof dispersed therein, wherein the drug layer is sufficiently designed to release the second amount of the antiemetic drug over a period of at least 1 hour, wherein the solid oral dosage form is sufficiently designed to release the first amount of the first antiemetic drug and the second amount of the second antiemetic drug over a minimum period of 16 hours. | 2014-09-18 |
20140271888 | DIKETOPIPERAZINE MICROPARTICLES WITH DEFINED SPECIFIC SURFACE AREAS - Disclosed herein are diketopiperazine microparticles having a specific surface area of less than about 67 m | 2014-09-18 |
20140271889 | MULTIFUNCTIONAL METAL NANOPARTICLES HAVING A POLYDOPAMINE-BASED SURFACE AND METHODS OF MAKING AND USING THE SAME - The present invention provides nanoparticles including a metallic core having a length along each axis of from 1 to 100 nanometers and a coating disposed on at least part of the surface of the metallic core, wherein the coating comprises polydopamine, along with methods for making and using such nanoparticles. The metallic core may be gold, silver or iron oxide and the polydopamine coating may have other substances bound to it, such as silver, targeting ligands or antibodies, or other therapeutic or imaging contrast agents. The disclosed nanoparticles can be targeted to cells for treating cancer or bacterial infections, and for use in diagnostic imaging. | 2014-09-18 |
20140271890 | CONTROLLED-RELEASE PHARMACEUTICAL COMPOSITION - The present invention relates to a controlled-release pharmaceutical composition which, when administered in the evening, promotes rapid sleep onset and makes it easy to wake up in the morning in a refreshing way. The composition comprises: a first portion having sleep-inducing activity, which is able to be degraded and absorbed in vivo within 5 minutes to 1 hour after administration; and a second portion having cognition-enhancing activity, which is able to be released in vivo after 4 to 8 hours from the start of absorption of the first portion. The composition, when administered in the evening, promotes rapid sleep onset and makes it easy to wake up in the morning in a refreshing way. | 2014-09-18 |
20140271891 | PHENYLEPHRINE RESINATE PARTICLES AND USE THEREOF IN PHARMACEUTICAL FORMULATIONS - Phenylephrine particles suitable for solid, semi solid or liquid dosage forms are disclosed. | 2014-09-18 |
20140271892 | PHENYLEPHRINE RESINATE PARTICLES HAVING GOOD AUC - Phenylephrine particles suitable for solid, semi solid or liquid dosage forms are disclosed. | 2014-09-18 |
20140271893 | COATED PHENYLEPHRINE PARTICLES AND USE THEREOF IN PHARMACEUTICAL FORMULATIONS - Phenylephrine particles suitable for solid, semi solid or liquid dosage forms are disclosed. | 2014-09-18 |
20140271894 | MATRIX-INCORPORATED FLUORESCENT POROUS SILICA PARTICLES FOR DRUG DELIVERY - A fluorescent porous silica particle for drug delivery includes a bridged silane fluorescent dye incorporated throughout the particle's matrix. Copolymerization of a bridged silane fluorescent dye (e.g., (R′O) | 2014-09-18 |
20140271895 | Polymorph Compositions, Methods of Making, and Uses Thereof - The described invention provides a biodegradable, biocompatible delivery system of flowable sustained release microparticulate composition of a substantially pure crystalline form of a bioactive agent such as, for example, nimodipine, a process of preparing a therapeutic form of a substantially pure crystalline form of the bioactive agent and a method for treating an interruption of a cerebral artery in a subarachnoid space at risk of interruption caused by brain injury in a mammal, which reduces signs or symptoms of at least one delayed complication associated with brain injury. | 2014-09-18 |
20140271896 | TAMPER RESISTANT PHARMACEUTICAL FORMULATIONS - Disclosed in certain embodiments is a solid oral dosage form comprising a plurality of particles, each particle comprising (i) a core comprising an active agent susceptible to abuse and an internal adhesion promoter, wherein the cores are (i) dispersed in a matrix comprising a controlled release material or (ii) coated with a controlled release material. The dosage form can also include an alcohol resistant material. | 2014-09-18 |
20140271897 | COMPOSITIONS, METHODS AND DEVICES FOR LOCAL DRUG DELIVERY - This invention provide novel compositions, methods and devices for sustained drug delivery. The microencapsulated sustained drug delivery compositions are deposited using oscillating needle apparatus oscillating at 10-12000 minutes per minutes. The injected compositions may undergo variety of physical chemical changes upon deposition. The physical and chemical changes enables improved drug encapsulation and sustained drug release. Also described are new methods to form polymer microparticles or polymer films/implants in situ inside the tissue. The invention also describes colored biodegradable microparticle based compositions wherein the compositions comprise drug encapsulated microparticles and coloring agent encapsulated microparticles mixed in any proportion. Medical applications of the compositions and methods described in this invention are also described. | 2014-09-18 |
20140271898 | ABUSE DETERRENT COMPOSITIONS AND METHODS OF USE - Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties. | 2014-09-18 |
20140271899 | METHOD OF ENHANCING THE BIODISTRIBUTION AND TISSUE TARGETING PROPERTIES OF THERAPEUTIC CECO2 PARTICLES VIA NANO-ENCAPSULATION AND COATING - The present invention provides methods and liposomal compositions useful in therapeutics, and diagnosis, prognosis, testing, screening, treatment and/or prevention of various disease conditions. The present invention provides imaging methods for various conditions. The present invention is a multi-layered drug delivery pathway, inclusive of nanoparticle liposomal formulations and mechanisms of localized action via unzipping upon delivery to the affected tissue site. The nano-encapsulation methodology allows maximization of a potent antioxidant's biocompatibility, increased target cell penetration and uptake, reduced off-target effects and retention of high anti-oxidative activity for promising therapeutic potential. | 2014-09-18 |
20140271900 | High Cleaning Silica with Low Abrasion and Method for Making Same - Silica materials having high cleaning and low abrasion properties are described, together with methods of making such materials and dentifrice compositions comprising the silica materials. | 2014-09-18 |
20140271901 | Management of Tractional Membranes - Methods and compositions are provided here to manage tractional membranes, as well as other diseases and disorders of the eye. Compositions comprising microbubbles associated with enzymes or vitreolytic agents, are provided. The method of the present invention involves administration of the microbubble and an enzyme or vitreolytic agent to a subject in need thereof, followed by application of ultrasound. | 2014-09-18 |
20140271902 | PARTICULATE HYALURONIC ACID FORMULATIONS FOR CELLULAR DELIVERY OF BIOACTIVE AGENTS - There is presently provided a suspension of immiscible particles in a solution, wherein the particles comprise an agglomeration of a bioactive agent; and a plurality of conjugates of a hyaluronic acid and a flavonoid wherein the particles are on average from about 15 nm to about 300 nm in diameter and wherein the bioactive agent is releasably retained in the particles by the flavonoid. There is also provided a therapeutic formulation comprising such a suspension and methods for using the suspension and therapeutic formulation, including for delivery of a bioactive agent to a cell and for treating a disease, including cancer. | 2014-09-18 |
20140271903 | USE OF THERMO-SENSITIVE GEL FOR CONTROLLED DELIVERY OF ALK-5 INHIBITORS TO THE EYE AND RELATED METHODS - The present invention relates to a methods for extending the period of filtering bleb survival and/or providing for long term bleb survival following Glaucoma Filtration Surgery by delivering an ALK-5 inhibitor to a wound area (the surgical site) of a patient's eye. More particularly, the present invention relates to a method for the controlled delivery of an ALK-5 inhibitor to patient's eye using a thermo-sensitive polymer formulation, wherein the ALK-5 inhibitor is first contained in the polymer formulation at a temperature sufficient to maintain the formulation as a liquid and then applied to the eye wound opening, wherein the formulation turns to a gel. The use of the thermo-sensitive gel with ALK-5 inhibitor contained therein, provides for longer term bleb survival following Glaucoma Filtration Surgery (GFS) on a patient's eye. Thus, the present invention is particularly effective in inhibiting ocular fibrotic wound response following GFS. | 2014-09-18 |
20140271904 | METHODS FOR PREPARING TISSUE IMPLANTS - A method is provided for preparing a biological tissue for implantation. The method includes providing a biological tissue from a human or animal donor, treating the biological tissue with an antiviral treatment formulation, lysing the biological tissue, decellularizing the biological tissue with a decellularization treatment formulation, and decontaminating the biological tissue with an alkaline alcohol solution. The antiviral treatment formulation may include a solution of peracetic acid and an alcohol, wherein the peracetic acid is present in the antiviral treatment formulation at a concentration from about 0.03% to about 1.2% (v/v). The decellularization solution may include a solution of a polar aprotic solvent, such as dimethyl sulfoxide, benzyl alcohol and ethanol. | 2014-09-18 |
20140271905 | Neural Progenitor Cell Differentiation - Differentiation and stability of neural stem cells can be enhanced by in vitro or in vivo culturing with one or more extracellular matrix (ECM) compositions, such as collagen I, IV, laminin and/or a heparan sulfate proteoglycan. In one aspect of the invention, adult mammalian enteric neuronal progenitor cells can be induced to differentiate on various substrates derived from components or combinations of neural ECM compositions. Collagen I and IV supported neuronal differentiation and extensive glial differentiation individually and in combination. Addition of laminin or heparan sulfate to collagen substrates unexpectedly improved neuronal differentiation, increasing neuron number, branching of neuronal processes, and initiation of neuronal network formation. In another aspect, neuronal subtype differentiation was affected by varying ECM compositions in hydrogels overlaid on intestinal smooth muscle sheets. The matrix compositions of the present invention can be used to tissue engineer transplantable innervated GI smooth muscle constructs to remedy aganglionic disorders. | 2014-09-18 |
20140271906 | NGNA COMPOSITIONS AND METHODS OF USE - The present invention relates to the field of viral disorders, and in particular to viral obesity. Compositions comprising nutraceutical agents are provided for treating viral obesity. Additionally, compositions comprising nutraceutical agents targeting adenoviruses are provided. | 2014-09-18 |
20140271907 | COMPOSITIONS COMPRISING EICOSAPENTAENOIC ACID AND KRILL OIL AND METHODS OF USE THEREOF - The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases. | 2014-09-18 |
20140271908 | DIETARY SUPPLEMENTS AND METHODS FOR PREVENTING AND TREATING MIGRAINES - This document provides methods and materials related to preventing and treating migraines. For example, compositions (e.g., dietary supplements) containing one or more of coenzyme Q10, magnesium, riboflavin, pine bark extract, and fish oil are provided. | 2014-09-18 |
20140271909 | Methods for Segregating Particles Using an Apparatus with a Size-Discriminating Separation Element Having an Elongate Leading Edge - The disclosure relates to an apparatus for segregating particles on the basis of their ability to flow through a stepped passageway. At least some of the particles are unable to pass through a narrower passageway bounded by a segregating step, resulting in segregation of the particles. The breadth of the leading edge of at least one step of the apparatus is significantly greater than the overall width of the passageway in which the step occurs, permitting high and rapid sample throughput. The apparatus and methods described herein can be used to segregate particles of a wide variety of types. By way of example, they can be used to segregate circulating tumor cells from a human blood sample. | 2014-09-18 |
20140271910 | Methods for treating urushiol-induced contact dermatitis - The invention is directed to methods for treating urushiol-induced contact dermatitis. Specifically, the invention is directed to treating and reducing inflammation associated with poison ivy, poison sumac and poison oak by administering to a subject suffering from such conditions novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing solution compositions (referred to herein as “SR-CFS” compositions). | 2014-09-18 |
20140271911 | LITHIUM AND A BETA-SECRETASE INHIBITOR FOR THE TREATMENT OF ALZHEIMER'S DISEASE - This invention is a pharmaceutical composition comprising of lithium as an active ingredient, to decrease intracellular calcium ion concentrations, and a beta-secretase inhibitor as an active ingredient, to reduce beta-secretase activity; for the treatment and prevention of disease, including disease characterized by the abnormal cleavage of amyloid precursor protein. | 2014-09-18 |
20140271912 | SODIUM CONTAINING SOL-GEL DERIVED BIOACTIVE GLASSES AND USES THEREOF INCLUDING HEMOSTASIS - A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof which include introducing Na | 2014-09-18 |
20140271913 | COMPOSITIONS AND METHODS FOR MANUFACTURING SOL-GEL DERIVED BIOACTIVE BOROPHOSPHATE GLASSES FOR MEDICAL APPLICATIONS - A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof which include at least 5 weight percent CaO, at least 10 weight percent P | 2014-09-18 |
20140271914 | BONE GRAFT MATERIALS CONTAINING CALCIUM PHOSPHATE AND CHITOSAN - Described herein are materials and methods for increasing the osteoconductivity of a bone graft material, reducing the risk of infection at a surgical site, and increasing hemostasis. The bone graft materials described herein contain calcium phosphate and a form of chitin. In another embodiment the bone graft materials further comprises collagen. Chitin has been demonstrated to provide increased rate of new calcium phosphate growth, increased hemostasis, as well as antimicrobial properties. Various methods for manufacturing the bone graft materials described herein are also contemplated. | 2014-09-18 |
20140271915 | USE OF DERIVATIVES CONTAINING C-O-P BONDS IN PATIENTS WITH KIDNEY FAILURE - Use of a derivative containing C—O—P bonds in a controlled release form to treat patients with kidney failure. Moreover, it comprises the use of said derivatives together with other active substances, which particularly may be selected from a list comprising a calcimirnetic, vitamin, phosphate binder, thiosulfate, bisphosphonate, pyrophosphate, citrate, diuretic, antihypertensive and anticholesteraemic agent. | 2014-09-18 |
20140271916 | MULTIVALENCE PHOTOCATALYTIC SEMICONDUCTOR ELEMENTS - Described herein are elements comprising a p-type semiconductor comprising mixed valence oxide compounds and an n-type semiconductor having a deeper valence band than the p-type semiconductor valence bands wherein the semiconductor types are in ionic communication with each other. The elements enhance photocatalytic activity. | 2014-09-18 |
20140271917 | CONTROLLED AND PREDICTABLE 2-PATH-WAY DECOMPOSITION OF THERMODYNAMICALLY DOUBLE UNSTABLE OXIDISING AGENTS - Disclosed herein is a method comprising: obtaining characteristics of a cleaning or disinfection application; querying a database comprising experimental relationships, theoretical relationships or both, between the characteristics of the cleaning or disinfection application and a composition; determining one or more compositions suitable for the cleaning or disinfection application based on the characteristics and the database. | 2014-09-18 |
20140271918 | TANNIN FORMULATION FOR TREATING GASTROINTESTINAL SPASMS TRIGGERED BY STRESS - Methods of treating gastrointestinal spasms are provided. For example, methods of treating gastrointestinal spasms are provided, such methods not requiring the use of systemic drugs that have shown to (i) provide slow relief, (ii) cause adverse side effects, (iii) limit activities, (iv) worsen existing gastrointestinal conditions, (v) be unrecommended in several gastrointestinal conditions that include gastrointestinal spasms, or (vi) be unrecommended in the absence of diarrhea. | 2014-09-18 |
20140271919 | Topical Copper Ion Treatments and Methods of Treatment Using Topical Copper Ion Treatments in the Genital-Rectal Areas of the Body - Copper ion treatments and methods of treatment are provided to treat various body conditions affecting the genital and/or rectal areas. The copper ion treatments contain a copper ion-containing solution which, as a result of the copper ions contacting anatomical tissue of the vagina, the rectal canal and/or the external genital or rectal areas, brings about local and systemic therapeutic effects. The copper ion treatments and methods for treating conditions affecting the genital and/or rectal areas involve the use of tampons, suppositories, lotions, creams, gels, foams and solutions, each containing a copper ion-containing solution. The tampon bodies and the copper ion lotions, creams, gels and foams may be delivered into the vagina, and the suppositories can be delivered into the vagina or into the rectal canal. The copper ion lotions, creams, gels, foams and solutions may also be topically applied to the external genital and/or rectal areas. | 2014-09-18 |
20140271920 | SKIN OINTMENT FORMULATION - An ointment formulation for treating a skin of a mammal includes an occlusive and nourishing ingredient in an amount configured to reduce moisture evaporation from and seal the skin, and supply amino acids to the skin. The formulation also includes an anti-pruritic ingredient in an amount configured to reduce itching of the skin. Additionally, the formulation includes an antiseptic and anti-oxidant providing ingredient in an amount configured to protect the skin against infection. Furthermore, the formulation includes a moisturizing ingredient in an amount configured to soothe and reduce dryness of the skin. A method of generating an ointment formulation to treat a skin disorder is also disclosed. | 2014-09-18 |
20140271921 | PHARMACEUTICAL COMPOSITION - A topical composition comprises at least 5 wt % metronidazole or a pharmacologically acceptable derivative thereof in a non-aqueous vehicle. The composition may be used in the treatment of conditions of the colon, rectum, anorectum and perianal region, in particular inflammatory bowel disease and perianal Crohn's disease. The composition also relieves pain and inflammation and promotes healing of the colon, rectum, anorectum and perianal region following surgical operations. One advantage of the composition is that topical administration of metronidazole results in a primarily local effect and thus side effects observed from systemic administration are avoided. | 2014-09-18 |
20140271922 | PIRENZEPINE AS AN AGENT IN CANCER TREATMENT - The present invention generally relates to the neuroprotective activity of condensed diazepinones, e.g. condensed benzodiazepinones such as pirenzepine or compounds which are metabolized to condensed benzodiazepinones such as olanzapine. These compounds are suitable as co-medicaments for the prevention and/or treatment of drug-induced neurotoxic effects in general and neurotoxic side effects during cancer treatments with cytostatic drugs such as platinum-derivatives, e.g. cis-, carbo- and oxaliplatin, taxanes, bleomycin, cyclophosphamide and vincristine etc. Further, these compounds have an intrinisic anti-cancer activity on their own due to PARP-1 inhibition, which prevents NADH depletion in oxidative metabolism of healthy cells thus preventing the shift to anoxygenic, glycolytic metabolism present in many types of tumour cells thus eliminating this crucial metabolic advantage favouring tumour growth. These results exploit the fact of differential PARP-1 expression between many cancer cells and healthy tissues. | 2014-09-18 |
20140271923 | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions - Patients inflicted with various clustering chronic diseases require treatment with multiple drugs having distinct mechanisms of action. Accordingly, patients with multiple conditions suffer from cumulative side effects of multiple drugs as well as drug-drug interactions. Embodiments, agents, compounds or drugs of the present invention, such as sesquiterpenes, e.g., Zerumbone, replace an equal or larger number of approved drugs during patient treatment. Examples of disorders prevented or ameliorated by administration of the formulations of this invention include but are not limited to inflammatory diseases that may be, oncological, genetic, ischemic, infectious, neurological, hematological, ophthalmological, rheumatoid, orthopedic, neurological, hematological, kidney, vascular, dermatological, gynecological, or obstetric. The present invention further relates to a method of identifying agents, compounds or drugs useful in preventing or treating CDCP related diseases and conditions as well as other disorders, diseases and conditions treatable or preventable by the same agents, compounds or drugs. | 2014-09-18 |
20140271924 | COMPOSITION AND METHOD FOR BLOOD SUGAR MODULATION - Compositions and methods for modulating blood sugar are provided. The composition comprises gymnema, green coffee, grape seed, hibiscus, cinnamon, holy basil, Russian tarragon, ginger, turmeric, and chromium. | 2014-09-18 |
20140271925 | MODULATING SURFACE AND AEROSOL IODINE DISINFECTANT SYSTEM - A method and apparatus for producing aqueous iodine solutions to be used as a surface and aerosol disinfectant under continuous and dynamic flow conditions for medical applications comprises dissolving iodine into a first water flow thereby producing a concentrated aqueous iodine solution. The iodine solution is stored and then blended with a second water flow to produce a predetermined iodine disinfectant concentration of aqueous iodine. The disinfectant concentration is then stored and chemically adjusted to polarize to the species of iodine. The disinfectant concentration is then thermodynamically adjusted to maximize retention and disinfection variables. The iodine disinfectant is then ready to be used in an application requiring disinfection using iodine. | 2014-09-18 |
20140271926 | METHODS OF USE OF GLUTAMINE SYNTHETASE INHIBITORS - A method of treating neoplastic growth in a subject includes administering a glutamine synthetase (GS) inhibitor to the subject having neoplastic growth. A glutamine synthetase inhibitor may be administered in combination with thalidomide, lenalidomide and/or pomalidomide. Responsiveness to thalidomide, lenalidomide or pomalidomide therapy is determined by the expression levels of glutamine synthetase in neoplastic cells. | 2014-09-18 |
20140271927 | COMPOSITION AND METHOD FOR TREATING NEUROPATHY - The present invention provides therapeutic and nutrient compositions comprising Alpha lipoic acid, gammalinolenic acid, chromium, selenium, and optionally iodine for the treatment of diabetic neuropaty. These compositions ameliorate the condition and symptoms associated with the complications of lack of triiodothyronine in the nucleus of target cells, in particular and the pathological effects of the vaso nervorum. | 2014-09-18 |
20140271928 | PLANT-BASED COMPOSITIONS AND USES THEREOF - The present invention relates to compositions comprising a plant material and methods for using the same. The methods include extracting or removing a substance from a substrate, or remediating a substrate from a substance. The substance can comprise a hydrocarbon-containing substance, a protein, lipid, wax, fatty acid or fatty alcohol, grease, fat, oil or a combination thereof. | 2014-09-18 |
20140271929 | CITRATE CONTAINING BEVERAGE - Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions. | 2014-09-18 |
20140271930 | NONINVASIVE METHOD FOR MEASURING METABOLITES FOR SKIN HEALTH - A noninvasive method for diagnosing skin health in a subject comprising collecting a skin sample from the subject; detecting a level of one or more small molecule biomarkers in the epithelial cell sample/skin cell sample; diagnosing the subject as having a skin condition based on the level of a detected small molecule biomarker, wherein the detected small molecule is at least one compound chosen from: a compound generated by metabolism of amino acids, a compound generated by dipeptides metabolism, a compound generated by nucleic acids, a compound generated by metabolism of lipids, a compound generated by metabolism of carbohydrates, and mixtures thereof and further small molecule biomarkers as listed in Table 1. Further, a noninvasive method for evaluating the efficacy of products for skin health. | 2014-09-18 |
20140271931 | Anti-Acne Topical Films - Topical formulations containing one or more pharmaceutically acceptable bioadhesive film-forming agent, one or more anti-acne agent, and an aqueous solvent in the form of a solution or suspension are described herein. The formulation may further contain one or more excipients, including evaporation suppressants, humectants, or plasticizers. When the formulation is contacted with the skin of a patient, the solvent evaporates and forms a thin, transparent, and solid bioadhesive film. The bioadhesive film adheres to the skin surface for a prolonged period of time and the anti-acne agent is released into the skin over a prolonged period of time. Typically, the bioadhesive film adheres to the skin for at least 60 minutes following administration of the formulation, preferably for at least 8 hours following administration, more preferably up to 24 hours following administration. The prolonged retention of the anti-acne agent at the site increases the amount of uptake into the skin. | 2014-09-18 |
20140271932 | RODENTICIDAL COMPOSITION AND METHOD - A rodenticidal composition comprising a carbon dioxide release agent and a carrier may be disclosed. A method of controlling rodents at a locus by applying the composition of the disclosure may be disclosed. | 2014-09-18 |
20140271933 | Universal Potent Healing Tonic - The present invention relates to a method of consuming a universal potent healing tonic. When consumed according to the method, of a host of medical ailments can be abated including cancer, arthritis, and insomnia. | 2014-09-18 |
20140271934 | PEPTIDE SYSTEMS AND METHODS FOR METABOLIC CONDITIONS - The present invention generally relates to compositions and methods for topical or transdermal delivery, and treatment of metabolic conditions. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (TRH) and/or GnRH (gonadotropin-releasing hormone). The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other structures containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like. | 2014-09-18 |
20140271935 | METHODS AND SYSTEMS FOR TREATING OR PREVENTING CANCER - The present invention generally relates to compositions and methods for treatment of subjects having or at risk of cancer or other conditions. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (TRH) and/or GnRH (gonadotropin-releasing hormone). The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other structures containing nitric oxide. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like. | 2014-09-18 |
20140271936 | MEMORY OR LEARNING USING PEPTIDE AND OTHER COMPOSITIONS - The present invention generally relates to compositions and methods for topical or transdermal delivery, including treatment and prevention of learning and memory disorders, and enhancement of learning or memory. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (TRH) and/or GnRH (gonadotropin-releasing hormone). The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other structures containing nitric oxide and/or peptide. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like. | 2014-09-18 |
20140271937 | BRAIN AND NEURAL TREATMENTS COMPRISING PEPTIDES AND OTHER COMPOSITIONS - The present invention generally relates to compositions and methods for treatment of subjects in need of muscle growth, muscle repair, improved muscular and neuromuscular control, and treatments for neuromuscular and neurological disorders, including brain disorders. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (TRH) and/or GnRH (gonadotropin-releasing hormone). The nitric oxide and/or peptides may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other structures containing nitric oxide and/or peptide. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin, e.g., onto a location where muscle growth, muscle repair, or improved muscular and neuromuscular control is desired, or on another suitable portion of the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like. | 2014-09-18 |
20140271938 | SYSTEMS AND METHODS FOR DELIVERY OF PEPTIDES - The present invention generally relates to compositions and methods for topical or transdermal delivery. The compositions can be used in a variety of applications. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (TRH) and/or GnRH (gonadotropin-releasing hormone). The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other structures containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. The composition can also be applied to a mucosal surface in some instances. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like. | 2014-09-18 |
20140271939 | CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) - Various systems, devices, NO | 2014-09-18 |
20140271940 | BIOACTIVE CONCENTRATES AND USES THEREOF - The present invention relates to concentrates obtained from extraction from | 2014-09-18 |
20140271941 | Method For Producing Dry Extracts - The invention relates to a method for producing dry extracts of plants and to pharmaceutical preparations containing the same, more particularly phytopharmaceuticals, which contain at least one ethanolic/aqueous extract of a plant (drug), the plants being selected from the group consisting of: | 2014-09-18 |
20140271942 | BOTANICAL EXTRACT FROM THE AQUEOUS STREAM OF THE PALM OIL MILLING PROCESS FOR THE PREVENTION AND INHIBITION OF OXIDATIVE STRESS AND HAEMOLYSIS IN HUMAN RED BLOOD CELLS - The invention provides a composition for the prevention and inhibition of oxidative stress and haemolysis in human red blood cell wherein said composition compounds obtained from the aqueous stream of palm oil milling (palm oil vegetation liquor), in particular from vegetative liquor from the milling of palm oil fruit. | 2014-09-18 |
20140271943 | Dietary Composition and Method for Preventing, Reducing, Alleviating or Treating Idiopathic Vomiting - The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HT3a and/or NK-1 receptor for preventing or treating idiopathic vomiting. | 2014-09-18 |
20140271944 | Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal - An antioxidant-promoting composition that increases antioxidant defense potential in a subject is disclosed. The composition contains | 2014-09-18 |
20140271945 | IMMUNOASSAY OF S-ADENOSYLMETHIONINE USING ANALOGS THEREOF AND PERSONALIZED THERAPEUTICS - A method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence or absence of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual. | 2014-09-18 |
20140271946 | MODIFYING TASTE AND SENSORY IRRITATION OF SMOKELESS TOBACCO AND NON-TOBACCO PRODUCTS - Tobacco products comprising smokeless tobacco products and active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel are disclosed. Nicotine replacement therapies comprising active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel. The active ingredient may reduce or eliminate sensory irritation arising due to use of the product. Analgesic compositions comprising active ingredients. Methods of reducing taste and sensory irritation by employing an active ingredient. | 2014-09-18 |
20140271947 | Nutritional Supplement - A dietary supplement and method of supplementation comprises a vegetable component consisting essentially of juices extracted from two parts by weight fresh, unpeeled carrots; one part by weight fresh, unpeeled beet root; one part by weight of fresh, unpeeled cucumber; and a selected quantity of aloe vera juice. A cleansing component includes at least one of the following: about 2 fluid ounces (59.1 ml) of lemon juice; about 1.5-2 fluid ounces (44.3 to 59.1 ml) of lime juice; about 1 fluid ounce (29.6 ml) of aloe vera juice; and about 4-6 fluid ounces (118.3 to 177.4 ml) of cranberry juice. The vegetable component is ingested orally twice daily and the cleansing component is ingested orally once daily. | 2014-09-18 |
20140271948 | ANTIMICROBIAL SOLUTION FOR USE WITH DENTAL APPLIANCES - In various aspects, the composition of matter disclosed herein includes an antimicrobial solution. The antimicrobial solution may include deionized water QS, acetic acid, and grapefruit seed extract (GSE) in combination with one another. The GSE may be at a concentration effective to eradicate microorganisms, and the microorganisms may include both Gram-positive microorganisms and Gram-negative microorganisms. This Abstract is presented to meet requirements of 37 C.F.R. §1.72(b) only. This Abstract is not intended to identify key elements of the apparatus and methods disclosed herein or to delineate the scope thereof. | 2014-09-18 |
20140271949 | Composition and Method for Preventing, Reducing, Alleviating or Treating Idiopathic Vomiting - Compositions containing one or more compounds with inhibitory effect on a 5-HT3a and/or NK-1 receptor are effective for preventing or treating idiopathic vomiting in a mammal. | 2014-09-18 |
20140271950 | Natural Fungicide Composition - A method for treating Black Sigatoka fungus in crops of the Musaceae family by applying a fungicidal composition comprising garlic oil, rosemary oil, thyme oil and cinnamon oil. | 2014-09-18 |
20140271951 | SUGAR-ENRICHED EXTRACT DERIVED FROM TOBACCO - The present disclosure describes methods of obtaining and/or deriving a sugar-enriched extract from plants of the | 2014-09-18 |
20140271952 | PROTEIN-ENRICHED TOBACCO-DERIVED COMPOSITION - The present disclosure describes methods of obtaining and/or deriving proteins from plants of the | 2014-09-18 |
20140271953 | Use of Melicope Extracts to Improve Conditions Caused by Excess Lipids - Methods of using extracts of | 2014-09-18 |
20140271954 | Toxin Expelling Powder Comprising Root of Buckwheat and Preparation Process Thereof - The present invention provides tartary buckwheat detox powder and a method for preparing the same. Raw materials are loveyly hemsleya root, Sophora flavescens root, tartary buckwheat and dried ginger. The method comprises precessing the materials by freezing, wetting, acidifying, alkalizing, salifying, fermenting, steaming, boiling, baking, etc.; crushing and then formulating the resultant into watered pills or capsules, packaging and storing. The detox powder can be used for treating fatty liver disease, alcohol liver disease, hepatitis, liver cancer, liver cirrhosis, and ascites accompanied with liver cancer of late stage. | 2014-09-18 |
20140271955 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS - Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes. | 2014-09-18 |
20140271956 | HIGH MOISTURIZING CLEANSING COMPOSITION - The present invention relates to a lamellar structure which stabilizes oil and to a cleansing composition comprising the lamellar structure. More particularly, the present invention relates to a lamellar structure, which stabilizes oil to be used in a cleansing composition so that high-content oil is converted to a lamellar phase and contained in a composition. The present invention also relates to a cleansing composition which comprises the lamellar structure which enables the composition to contain high-content oil in a stable manner and to thus provide superior moisturizing ability. | 2014-09-18 |
20140271957 | COMPOSITION CONTAINING AN ESSENTIAL OIL PRODUCT AND METHOD FOR USING SUCH TO MAINTAIN NORMAL LEVELS OF TESTOSTERONE - A composition useful for maintaining healthy levels of testosterone in men and women. The composition includes essential oils from a tree of the genus | 2014-09-18 |
20140271958 | TOOLLESS COTTON CANDY MACHINE - A cotton candy machine includes a floss head comprised of a floss head cap, a heated filament spinning screen, a floss head base and a rotatable retaining cap, all removable from said head without tools by manually rotating said retaining cap. A floater includes a vane, a shank and a shank end. Sockets on the upper surface of the retaining cap capture the shanks of plural floaters. The floaters are relative rigid and of selective pitch to produce sugar fiber cooling air flow, and are non-porous for enhanced cleaning. The floss head is easily manually disassembled for cleaning. | 2014-09-18 |
20140271959 | PROCESS AND APPARATUS FOR MOULDING AND CURING TYRES - An apparatus for moulding and curing a green tyre includes a curing mould that includes a first sidewall plate and a second sidewall plate, with a ring of circumferential sectors circumscribing a mould cavity. The first sidewall plate is capable of coming into contact with a first annular fixing structure of the green tyre when the green tyre is inserted into the mould. The apparatus also includes at least a first bead moulding ring movable from a first contracted operating position to a second extended operating position, a second bead moulding ring movable from a first contracted operating position to a second extended operating position, and an expandable bladder delimited by a membrane associated for operation with the mould to exert a pre-moulding pressure which is lower than a moulding pressure to bring the first annular fixing structure into contact with the first sidewall plate. | 2014-09-18 |
20140271960 | CUTTER HUB PIN DRIVE MECHANISM AND QUICK DISCONNECT HUB FOR AN UNDERFLUID PELLETIZER - A cutter hub pin drive mechanism and a quick disconnect hub for a pelletizer and a pelletizer having a cutter hub pin drive mechanism are provided. The pelletizer has a cutter hub that includes a cutter hub holder which is engaged with the pelletizer shaft through a plurality of drive pins. The drive pins ride in drive pin channels formed by grooves cut into an inner surface of the cutter hub holder and aligned grooves formed in the outer surface of the forward end of the pelletizer shaft. By machining of grooves into the cutter hub holder and shaft to form channels that receive the drive pins, more precise engagement between the pelletizer shaft, cutter hub holder and drive pins is obtained, resulting in improved torque transmission from the shaft to the cutter hub. Also provided is a seal around the pelletizer shaft to prevent the egress of fines into the drive pin area which might otherwise interfere with the unobstructed movement of the cutter hub holder necessary to adjust blade position. Finally, a quick disconnect hub is provided by which the pelletizer shaft can be readily disconnected from the cutting assembly to facilitate the removal of agglomerated polymer in the cutting chamber. | 2014-09-18 |
20140271961 | INSERTING INHIBITOR TO CREATE PART BOUNDARY ISOLATION DURING 3D PRINTING - A 3D printing system may print a desired 3D object. A fusible powder may fuse when subjected to a fusing condition. A deposition system may deposit portions of the fusible powder on a substrate. A fusing system may apply the fusing condition to the deposited fusible powder. Inhibitor material may not fuse when subjected to the fusing condition. An insertion system may insert a portion of the inhibitor material between portions of the deposited fusible powder after having been deposited by the deposition system, but before being fused by the fusing system, so as to form a boundary that defines at least a portion of a surface of the desired 3D object. | 2014-09-18 |
20140271962 | TRIPLE PARISON COEXTRUSION MULTI-LAYER FLOWHEAD APPARATUS - A triple parison flowhead apparatus for producing three multi-layer parisons simultaneously. The triple parison flowhead includes a first parison flowhead, a second parison flowhead, and a third parison flowhead substantially abutted to one another. Each flowhead includes a plurality of rings having flow passages, defining a center axis, and having an annular flow conduit in fluid communication with the flow passages and a plurality of ports. A set of mold plattens having a width is located adjacent to the first, second, and third parison flowheads. The flow passages in each ring are defined by a height and a diameter of each ring, and a combination of the width of the mold plattens and the flow passages minimizes the center-to-center distances between the three parison flowheads. | 2014-09-18 |
20140271963 | POST-MOLD SYSTEM - Disclosed herein, amongst other things, is a post-mold system ( | 2014-09-18 |
20140271964 | Three-Dimensional Printing and Scanning System and Method - Disclosed herein are systems and methods for three-dimensional (3D) printing and scanning (or rapid prototyping). For example, presented herein are 3D printing and scanning systems and methods to create a 3D replica of a 3D object on a build surface. Movements and/or controls of the system are generally based on polar coordinates relative to a center of a build surface. System components may generally include: (1) a rotatable build surface; (2) a media extruder positioned over the build surface; (3) a heating element to melt media as it is drawn into the extruder; (4) an extruder positioning system coupled to the extruder and configured to move the extruder over the build surface based on polar coordinates relative to a center of the build surface; and (5) an optical scanning system for scanning of a 3D object to obtain a plurality of two-dimensional (2D) images of the 3D object. | 2014-09-18 |
20140271965 | SELECTIVE LASER SOLIDIFICATION APPARATUS AND METHOD - A selective laser solidification apparatus including: a powder bed onto which a powder layer can be deposited, a gas flow unit for passing a flow of gas over the powder bed along a gas flow direction, a laser scanning unit for scanning a laser beam over the powder layer to selectively solidify at least part of the powder layer to form at least one object and a processing unit for selecting a scanning sequence of the laser beam based on the gas flow direction. | 2014-09-18 |
20140271966 | APPARATUS FOR PRODUCING A NONWOVEN PRODUCT IN A NON-INDUSTRIAL ENVIRONMENT - An apparatus for producing a non-woven product is disclosed. The apparatus is located substantially within an enclosure and includes a mold or former and at least two moveable material application heads. A controller controls various elements located within or connected to the enclosure. The footprint of the enclosure is smaller than 2 m×2 m. | 2014-09-18 |
20140271967 | CONSUMABLE ASSEMBLY FOR USE IN EXTRUSION-BASED LAYERED DEPOSITION SYSTEMS - A consumable assembly comprising a container portion configured to retain a supply of filament, a guide tube connected to the container portion, and a pump portion connected to the guide tube. | 2014-09-18 |
20140271968 | APPARATUS FOR PROCESSING PLASTIC MATERIAL - The invention relates to an apparatus for the pretreatment and subsequent conveying or plastification of plastics, with a container with a mixing and/or comminution implement that is rotatable around an axis of rotation, wherein, in a side wall, an aperture is formed, through which the plastics material can be removed, a conveyor being provided, with a screw rotating in a housing, wherein the imaginary continuation of the longitudinal axis of the conveyor in a direction opposite to the direction of conveying passes the axis of rotation, where, on the outflow side, there is an offset distance between the longitudinal axis and the radius that is parallel to the longitudinal axis, and in that screw rotates clockwise, when seen from the starting point of the screw in the direction towards the end or towards the discharge aperture of the conveyor. | 2014-09-18 |
20140271969 | Twin Screw Shaft Spacer Bearing - A twin screw extruder includes a barrel having a chamber, a discharge port, an extrusion molding die coupled to the discharge port of the barrel, axially extending first and second screw shafts, and a screw shaft support. The screw shaft support includes first and second spacer bearings disposed on the first and second screw shafts, and a first cross member including first and second loops slidably coupled to the first and second spacer bearings. A second cross member is spaced apart from the first cross member by a connection member, and also includes first and second loops slidably coupled to the first and second spacer bearings. The connection member is situated between the first spacer bearing and the second spacer bearing, and connected to the first cross member and the second cross member. | 2014-09-18 |
20140271970 | MODULAR SUPERCRITICAL FLUID MATERIALS PROCESSING SYSTEM - A modular system for processing an exfoliated aggregate material or a polymer composite material comprising the exfoliated aggregate, utilizing supercritical fluid processing is described. The modular system may provide exfoliated aggregate particulates, polymer composite materials or master batch polymer composite materials. | 2014-09-18 |
20140271971 | DEVICE TO PRODUCE BRIQUETTES - The subject of the invention is a method for the manufacture of briquettes from comminuted straw, as well as a device to manufacture briquettes from comminuted straw. The method consists in that comminuted straw is compressed in a continuous process using a screw-type extruder until the material reaches a temperature at which the material after pressing solidifies to a density exceeding 1.3 g/cm 3. The device has a screw ( | 2014-09-18 |
20140271972 | HEAT BRAKE - A heat brake for heating and softening a thermoplastic sheet for bending is disclosed. The heat brake has a split work piece support table having two edges defining a slot between adjacent portions of the table. A first plenum is provided below the split work support table. During operation, the first plenum has a negative pressure. Air is drawn into the first plenum through the slot when a work piece does not span the slot. When a work piece spans the slot, the flow of air into the first plenum is reduced. The heat brake has a tube heater with an outlet nozzle positioned in the first plenum. A portion of the tube heater is positioned in a second plenum which is pressurized during heating. Air is moved from the second plenum through the heater tube and is directed against a work piece supported on the table. | 2014-09-18 |
20140271973 | METHOD FOR MANUFACTURING CLIMATE CONTROL DUCT, AND CLIMATE CONTROL DUCT - A mold for manufacturing a climate control duct, which has a protrusion formed on an outer peripheral surface thereof and is formed from a foamed resin, includes a groove provided on at least a part of a surface of the mold for transfer of a shape of the protrusion. The groove of the mold satisfies a relation D2014-09-18 | |
20140271974 | CONFORMING COOLING METHOD AND MOLD - A conformal cooling method and mold includes a part producing mold having a fluid passage defined therein that includes a channel defined in a surface of the mold, a weld support received in the channel, and a bridge welded across the channel above the weld support for closing the channel and defining the fluid passage. To form the fluid passage, the weld support is installed in the channel defined in the mold surface and the bridge is welded across the channel above the weld support for closing the channel. | 2014-09-18 |
20140271975 | VENT APPARATUS - A vent apparatus for use in a mold defining an opening that includes a vent tube portion configured to extend through the opening of the mold and a secondary tube portion configured to mate with the first end portion of the vent tube portion. For example, the secondary tube portion may be used to seal the passageway at the first end portion and may define one or more membrane regions configured to melt during a mold process to unseal the passageway. | 2014-09-18 |
20140271976 | MOLDED PRODUCT DELIVERY APPARATUS AND BLOW MOLDING MACHINE - An object of the invention is to provide a molded product delivery apparatus capable of delivering a molded product without using a flange support structure limited to erected transfer or an inverted support pin limited to inverted transfer. | 2014-09-18 |
20140271977 | LOCKING APPARATUS FOR COMMON PLATE STEM ACTUATOR - A locking apparatus for a machine having multiple stems which axially reciprocate with respect to a stationary unit by linkage with a reciprocating common plate. The locking apparatus includes: (a) a first locking assembly capable of alternatively locking and unlocking one of the stems to the common plate; and (b) a second locking assembly capable of alternatively locking and unlocking one of the stems to the stationary unit. The second locking mechanism is configured so that, when the first locking assembly locks a stem to the common plate, the second locking mechanism automatically unlocks that stem from the stationary unit, and when the first locking assembly is unlocked from the common plate, the second locking mechanism automatically locks that stem to the stationary unit. | 2014-09-18 |