37th week of 2012 patent applcation highlights part 52 |
Patent application number | Title | Published |
20120232258 | Process for the Preparation and Purification of Topiramate - A process for the preparation of topiramate in an one pot reaction comprises the following steps: A) reacting 2,3:4, 5-bis-O-{1-methylethylidene)-β-D-fructopyranose with sulfurylchloride in xylene in the presence of an organic or inorganic base to form 2,3:4, 5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfuryl chloride, B) adding a second organic solvent to the mixture obtained in step A) C) reacting the mixture obtained in step B) with ammonia to form topiramate. | 2012-09-13 |
20120232259 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY - The present invention provides a novel lymphocyte inhibitory receptor termed BTLA which is expressed on both T and B cells, and identifies B7 family member B7x as interacting with BTLA to attenuate lymphocyte activity. Methods and compositions for modulating BTLA-mediated negative signaling and interfering with the interaction of BTLA and B7x for therapeutic, diagnostic and research purposes are also provided. | 2012-09-13 |
20120232260 | AMPHIPHILIC NUCLEOTIDE COCHLEATE COMPOSITIONS AND METHODS OF USING THE SAME - The present invention is directed to cochleate compositions that include a nucleotide that is associated with a positively charged amphiphile. The present invention also includes methods for making and using the compositions provided herein. | 2012-09-13 |
20120232261 | METHOD FOR MANUFACTURING LOW MOLECULAR WEIGHT HYALURONIC ACID - The present invention relates to a method for preparing low molecular weight hyaluronic acid from high molecular weight hyaluronic acid which is produced by | 2012-09-13 |
20120232262 | METHOD FOR PREPARING N-SUCCINIMIDYL N-BIOTINYL-6-AMINOCAPROATE - The invention relates to a method for preparing N-succinimidyl N-biotinyl-6-aminocaproate, characterised in that said method includes a step of activating N-biotinyl-6-aminocaproic acid in the form of a mixed anhydride, followed by coupling said mixed anhydride with N-hydroxysuccinimide. | 2012-09-13 |
20120232263 | Mimetics of Sulfated Oligosaccharides - The present invention is directed to sulfated oligosaccharides having 4, 5 or 6 saccharidic units and wherein a glycosidic bond between two saccharide units is substituted by a C—C bond, and wherein the sulfation degree expressed as percentage of OH groups substituted by a OSO | 2012-09-13 |
20120232264 | SYSTEM AND METHOD FOR TREATING BIOMASS - A biomass treatment apparatus (A) is constituted by a pressurized hot water reaction apparatus ( | 2012-09-13 |
20120232265 | 1,2-Disubstituted Heterocyclic Compounds - 1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms. | 2012-09-13 |
20120232266 | REDUCTION OF ORGANIC COMPOUNDS WITH LOW AMOUNTS OF HYDROGEN - The present invention relates to a process for the reaction of a compound with hydrogen wherein the reaction is conducted using a hydrogen-containing gas comprising up to about 10 vol. % hydrogen and at least about 90 vol. % of an inert gas and wherein the compound to be reacted with hydrogen is provided in a liquid phase. The process of the present invention is particularly suitable for hydrogenation and hydrogenolysis reactions. | 2012-09-13 |
20120232267 | PROCESS FOR CONTINUOUS HYDROGENATION OR HYDROGENATING AMINATION - A process continuously hydrogenating unsaturated compounds, in which particles of a first hydrogenation catalyst are suspended in a liquid phase in which an unsaturated compound is dissolved, the liquid phase, in the presence of a hydrogenous gas at a first partial hydrogen pressure and at a first temperature, is conducted through a packed bubble column reactor in cocurrent counter to the direction of gravity, the effluent from the bubble column reactor is sent to a gas-liquid separation, the liquid phase is sent to a crossfiltration to obtain a retentate and a filtrate, the retentate is recycled into the bubble column reactor and the filtrate, in the presence of a hydrogenous gas at a second partial hydrogen pressure and at a second temperature, is passed over a bed of a second hydrogenation catalyst, the second partial hydrogen pressure is at least 10 bar higher than the first partial hydrogen pressure. | 2012-09-13 |
20120232268 | Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics with a Third Group, and Methods for Production Thereof - Monovalent compounds having moieties comprising at least one amino acid side chain are bound to a core molecule, which also comprises a nucleophilic moiety bound to said core molecule. Monovalent compounds also comprise a macrocyclic ring, a nucleophilic moiety, and a spacer group. Monovalent compounds may be combined into bivalent and trivalent compounds, some of which may have a labeling tag. Methods of production of bivalent compounds and contemplated uses thereof are disclosed. | 2012-09-13 |
20120232269 | METHOD FOR CONTINUOUSLY PRODUCING MELAMINE - A process for the continuous production of melamine from urea by means of a fluidized-bed reactor, wherein process gas guided in the process circuit is used as fluidizing gas and wherein the temperature of the process gas at the inlet of the conveying means for the fluidizing gas is adjusted by adjusting the mixing ratio of a process gas stream guided over a scrubber and of a process gas stream guided past the scrubber. | 2012-09-13 |
20120232270 | HETEROAROMATIC PHTHALONITRILES - Disclosed are an oligomer and a phthalonitrile monomer having the formulas: | 2012-09-13 |
20120232271 | METHOD FOR PREPARATION OF OPTIONALLY 2-SUBSTITUTED 1,6-DIHYDRO-6-OXO-4-PYRIMIDINECARBOXYLIC ACIDS - A new method for the preparation of optionally 2-substituted 1,6-dihydro-6-oxo-4-pyrimidinecarboxylic acid compounds of Formula 1 is disclosed | 2012-09-13 |
20120232272 | PROCESS FOR PRODUCING v-COELENTERAZINE COMPOUNDS - A simple process for producing v-coelenterazine compounds has been desired. Described is a process for producing a v-coelenterazine compound represented by general formula (II) comprising (1) the step of reacting a compound of general formula (VIII) with a methyltriphenylphosphonium salt in the presence of a base to give a compound represented by general formula (IX), (2) the step of performing a ring-closing metathesis reaction on any one selected from the group consisting of the compound represented by general formula (IX) and a compound of general formula (X) which is the compound of general formula (IX) wherein the amino is protected with R | 2012-09-13 |
20120232273 | PROCESS FOR THE PREPARATION OF A DPP-IV INHIBITOR - The present invention is concerned with an improved process for the preparation of pyrido[2,1-a]isoquinoline derivatives of formula I | 2012-09-13 |
20120232274 | PROCESS FOR PREPARATION OF CLOPIODOGREL BISULFATE FORM-1 - An improved process for preparing crystalline form-1 of (S)-methyl 2-(2-chlorophenyl)-2-{6,7-dihydrothieno[3,2-c]pyridine-5(4H)-yl}acetate bisulfate (clopidogrel bisulfate) of formula I is provided The preparation comprises the straight conversion of an uncyclized material of (S)-methyl 2-[2-(thiophen-2-yl)ethylamino]-2-(2-chlorophenyl) acetate hydrochloride into clopidogrel bisulfate crystalline form-1 without any degradation of clopidogrel base | 2012-09-13 |
20120232275 | PROCESS FOR PREPARING 5-FLUORO-1H-PYRAZOLO [3,4-B] PYRIDIN-3-AMINE AND DERIVATIVES THEREOF - The present invention relates to a process for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine in high yield and purity. The present invention also relates to processes for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine derivatives. These processes are useful for preparing biologically active compounds, particularly certain GSK-3 inhibitors, or derivatives thereof. | 2012-09-13 |
20120232276 | PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF - A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyliphenyl)-3-(2-isopropenylphenyljpropyl methane sulphonate (styrene mesylate salt) (b) coupling with 1-(mercapto methyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt. | 2012-09-13 |
20120232277 | PROCESS FOR THE PREPARATION OF 1,2,4-OXADIAZOL-3-YL DERIVATIVES OF CARBOXYLIC ACID - The present invention discloses processes for the preparation and isolation of [1,2,4]oxadiazo-3-yl derivatives of carboxylic acids. The derivatives are useful in the treatment of inflammatory diseases and conditions. | 2012-09-13 |
20120232278 | Insecticidal Aryl Pyrrolidines - The present invention provides novel aryl pyrrolidines having an excellent insecticidal action as insecticides. Aryl pyrrolidines represented by the formula (I) and use thereof as insecticide. | 2012-09-13 |
20120232279 | Mild and Selective Vanadium-Catalyzed Oxidation of Benzylic, Allylic, and Propargylic Alcohols Using Air - The invention concerns processes for oxidizing an alcohol to produce a carbonyl compound. The processes comprise contacting the alcohol with (i) a gaseous mixture comprising oxygen; and (ii) an amine compound in the presence of a catalyst, having the formula: | 2012-09-13 |
20120232280 | DERIVATIVES OF (BRIDGED PIPERAZINYL)-1-ALKANONE AND USE THEREOF AS p75 INHIBITORS - The present invention relates to derivatives of ((phenyl)-3,6-dihydropyridin-1-yl)(bridged piperazinyl)-1-alkanone derivatives and ((phenyl)-2,5-dihydropyrrol-1-yl) (bridged piperazinyl)-1-alkanone corresponding to Formula (I): | 2012-09-13 |
20120232281 | PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2-[4-(METHYLSULFONYL)PHENYL]ETHANONE, AN INTERMEDIATE OF ETORICOXIB - A process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methyl sulfonyl)phenyl]ethanone, an intermediate of the synthesis of Etoricoxib. The synthesis of the intermediates useful for such preparation is also described. | 2012-09-13 |
20120232282 | FLUORESCENT NEAR INFRA-RED (NIR) DYES - A compound of formula (I) is described in which each A, which may be the same or different, is a halide selected from fluoride, chloride, bromide and iodide, or is O—Y, wherein Y is a substituted or unsubstituted, saturated or unsaturated, straight or branched chain alkyl moiety. R | 2012-09-13 |
20120232283 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE - The invention provides a production method of a biaryltetrazole derivative useful as an intermediate for an angiotensin II receptor antagonist. The method comprises reacting an aryltetrazole derivative with a benzene derivative, deprotecting or reducing the resulting compound, and halogenating the deprotected or reduced compound | 2012-09-13 |
20120232284 | Polymorph of a Pharmaceutical - A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed. | 2012-09-13 |
20120232285 | Sulfonyl-1,2,4-triazole salts - The invention relates to triazole salts, to their preparation and to applications thereof. The salts have at least one anionic triazolium group which carries at least one chlorosulphonyl, fluorosulphonyl or alkoxyfluorosulphonyl group, each of the anionic groups being combined with a proton or a cation that has a valency of less than or equal to 4. The salts are useful as synthesis reagents, as chemical-reaction or polymerization catalysts, and as ion-conducting materials for electrochemical generators, supercapacitors and electrochromic devices. | 2012-09-13 |
20120232286 | AZOLE DERIVATIVES, METHODS FOR PRODUCING THE SAME, INTERMEDIATE THEREOF, AGRO-HORTICULTURAL AGENTS - An azole derivative according to the invention is represented by Formula (I), wherein each of R | 2012-09-13 |
20120232287 | DETERGENT DISPERSANT AND LUBRICATING OIL COMPOSITION - A detergent dispersant contains a nitrogen-containing compound represented by the following formula (1). A lubricating oil composition contains the detergent dispersant. | 2012-09-13 |
20120232288 | TRI-, TETRA-SUBSTITUTED-3-AMINOPYRROLIDINE DERIVATIVE - An intermediate for production of a quinolone synthetic antibacterial agent and a therapeutic agent for an infection which exhibit broad spectrum and strong antibacterial activity for both Gram positive and Gram negative bacteria. | 2012-09-13 |
20120232289 | FIVE-MEMBERED CYCLOCARBONATE POLYSILOXANE COMPOUND AND PROCESS FOR PREPARATION OF SAME - A 5-membered cyclic carbonate polysiloxane compound is represented by the below-described formula (1), and is produced by a process that reacts an epoxy-modified polysiloxane compound with carbon dioxide. | 2012-09-13 |
20120232290 | REACTIVITY OF HYDROXYMETHYLGLUTARYL COENZYME A (HMG-COA) REDUCTASE INHIBITORS CONTAINING CONJUGATED DIENES WITH PHENOLIC ANTIOXIDANTS IN THE SOLID-STATE - The object of this invention was to probe the reactivity of lovastatin, simvastatin, pravastatin, and mevastatin in the solid-state without radical initiators in order to determine the antioxidant that provided the best stability for the statin. Phenolic antioxidants were evaluated. | 2012-09-13 |
20120232291 | CRYSTALLIZATION OF 4'-EPIDAUNORUBICIN X HCI - 4′-epidaunorubicin hydrochloride is provided in a crystalline form which is stable and readily soluble. A process of producing the crystalline form includes crystallizing 4′-epidaunorubicin hydrochloride in a solvent system including (a) solvent A selected from C | 2012-09-13 |
20120232292 | PROCESS FOR THE PREPARATION OF PRIMARY AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION - Process for the preparation of primary amines which have at least one functional group of the formula (—CH | 2012-09-13 |
20120232293 | PROCESS FOR PREPARING DI-, TRI- AND POLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION - Process for preparing primary amines which have at least one functional group of the formula (—CH | 2012-09-13 |
20120232294 | PROCESS FOR PREPARING ALKANOLAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION - Process for preparing alkanolamines which have a primary amino group (—NH | 2012-09-13 |
20120232295 | OXETANE-RING-CONTAINING (METH)ACRYLIC ACID ESTER COMPOUND - Provided is a novel oxetane-ring-containing (meth)acrylic ester compound which can give, through polymerization, a cured article being highly flexible or thermally stable. The oxetane-ring-containing (meth)acrylic ester compound is represented by formula (1) below, in which R | 2012-09-13 |
20120232296 | ANTISOLVENT SOLIDIFICATION PROCESS - The present invention relates to a antisolvent solidification process wherein a liquid medium comprising at least one organic or inorganic compound which is to be solidified is forced through a membrane into one or more antisolvents, or wherein one or more antisolvents are forced through a membrane into a liquid medium comprising at least one organic or inorganic compound which is to be solidified, yielding a composition comprising solid particles comprising said organic and/or inorganic compound(s). | 2012-09-13 |
20120232297 | Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds - The application discloses thiol ester molecules and α-hydroxy thiol ester molecules having a thiol group located on one of the final two carbon atoms in a carbon chain or a terminal or α-hydroxyl groups, respectively. The disclosed thiol ester molecules and or α-hydroxyl thiol ester molecules es may be made from unsaturated ester molecules having one or more terminal alkene groups. The disclosed techniques also provide methods for making unsaturated ester molecules having one or more terminal alkene groups by the metathesis of unsaturated esters having one or more internal carbon-carbon double bonds (e.g. natural source oils). The thiol ester molecules or α-hydroxy thiol ester molecule may be used in reactions with isocyanate monomers, epoxide monomer, or material having multiple alkene groups to make sealants, coatings, adhesives, and other products. | 2012-09-13 |
20120232298 | COMPOUNDS FOR PREPARING IMMUNOLOGICAL ADJUVANT - The present invention provides methods for preparing TLR-4 receptor agonist E6020: | 2012-09-13 |
20120232299 | Refractory Mixed-Metal Oxides and Spinel Compositions for Thermo-Catalytic Conversion of Biomass - A process for biomass catalytic cracking is disclosed herein. More specifically, the process is in presence of is a mixed metal oxide catalyst represented by the formula (X | 2012-09-13 |
20120232300 | SYSTEMS AND METHODS FOR MAKING BIOPRODUCTS - Processes for continuous preparation of bioproducts are described herein. The processes include contacting fatty acid glycerides with alcohols in the presence of an acidic heterogeneous catalyst and separating the fatty acid alkyl esters from the reaction products. | 2012-09-13 |
20120232301 | ANTIMICROBIAL COMPOUND AND PREPARATION THEREOF - The present invention relates to the field of organic synthesis, and provides an organosilicon betaine type antimicrobial compound having a general formula I and preparation thereof: | 2012-09-13 |
20120232302 | Process for the Preparation of (-)-(4-Chloro-Phenyl)-(3-Trifluoromethyl-Phenoxy)-Acetic Acid 2-Acetylamino-Ethyl Ester - The present invention is directed to a novel process for the preparation of (4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester, useful in the treatment of metabolic disorders and further to a process for the preparation of (4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid, a synthesis intermediate. | 2012-09-13 |
20120232303 | Crystalline Solid and Amorphous Forms of (-)-Halofenate and Methods Related Thereto - The present invention provides crystalline solid and amorphous forms of (−)-halofenate. The crystalline solid forms may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of conditions associated with blood lipid deposition in a mammal, particularly those diseases related to Type 2 diabetes and hyperlipidemia. The invention also relates to a method for preventing or treating Type 2 diabetes and hyperlipidemia in a mammal comprising the step of administering a therapeutically effective amount of crystalline solid and amorphous forms of (−)-halofenate. | 2012-09-13 |
20120232304 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BICYCLO [3.1.0] HEXANE DERIVATIVE USING ENZYME - There is provided a process for producing a bicyclo [3.1.0] hexane derivative represented by the formula (I) and a salt thereof including; causing an enzyme to act on an optically inactive compound represented by the formula (II) causing an asymmetric acylation reaction and a highly-stereoselective conversion to an optically active compound represented by the formula (III); and converting the compound represented by the formula (III) to the compound represented by the formula (I) or a salt thereof. | 2012-09-13 |
20120232305 | METHOD FOR PRODUCING A CARBOXYLIC ACID AMIDE FROM A CARBONYL COMPOUND AND HYDROCYANIC ACID - The invention relates to a method for producing a carboxylic acid amide from a carbonyl compound and hydrocyanic acid, comprising the steps of A) reacting a carbonyl compound with hydrocyanic acid to produce a hydroxycarboxylic acid nitrile, B) hydrolysis of the hydroxycarboxylic acid nitrile obtained in step A) in the presence of a catalyst comprising manganese dioxide, wherein a molar excess of carbonyl compound is used in relation to the hydrocyanic acid to react the carbonyl compound with hydrocyanic acid according to step A), and the reaction mixture obtained in step A) is not purified by distillation before the hydrolysis according to step B) is carried out. The invention furthermore relates to a method for producing alkyl(meth)acrylates from polymers, moulding compounds and moulded bodies, wherein a method for producing a carboxylic acid amide from a carbonyl compound and hydrocyanic acid is carried out in accordance with the method described above. | 2012-09-13 |
20120232306 | PROCESS FOR THE PREPARATION OF TAPENTADOL AND INTERMEDIATES THEREOF - The present invention refers to a new process for the synthesis of tapentadol comprising the quantitative resolution of the racemic mixture (V) to obtain the stereoisomer of (S)-3-(dimethylamino)-2-methyl-1-(3-nitrophenyl)-propan-1-one (VII) according to the Scheme 2 below | 2012-09-13 |
20120232307 | TWO-STAGE PROCESS FOR COST-EFECTIVE DEPOSITION OF HOMOGENEOUS CATALYSTS IN MDA SYNTHESIS - The invention provides a process for preparing diphenylmethanediamine, comprising the steps of:
| 2012-09-13 |
20120232308 | HIGH MOBILITY PERIODIC STRUCTURED ORGANIC FILMS - An high mobility structured organic film comprising a plurality of segments and a plurality of linkers arranged as a covalent organic framework, wherein the structured organic film may be a multi-segment thick structured organic film. | 2012-09-13 |
20120232309 | PROCESS FOR THE PREPARATION OF PRIMARY AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION - Preparing a primary amine by alcohol amination of alcohol with ammonia and elimination of water includes reacting, in a homogeneously catalyzed reaction, a mixture of alcohol, ammonia, nonpolar solvent, and catalyst, in a liquid phase, to obtain a product mixture. The process then includes phase separating the product mixture into a polar product phase and a nonpolar product phase, and separating off the nonpolar product phase. At least some of the nonpolar phase returns to the homogenously catalyzed reaction. The process further includes separating off amination product from the polar product phase. At least some of the catalyst is in the nonpolar phase, and the catalyst accumulates in the nonpolar phase. | 2012-09-13 |
20120232310 | PALLADIUM CATALYST AND PROCESS FOR PRODUCTION OF BISARYL COMPOUND USING SAME - Disclosed are: a novel palladium catalyst which does not undergo leakage, can be recycled, does not require the use of any phosphorus-containing ligand, and has a high catalytic activity; and a process for producing a novel bisaryl compound using the palladium catalyst. In the production of a bisaryl compound by reacting an aromatic halide with an aromatic boronic acid in the presence of a palladium catalyst and a base, the palladium catalyst comprises a dendrimer containing a silica particle as a core and a palladium compound dissolved in an ionic liquid and supported on the dendrimer. | 2012-09-13 |
20120232311 | Method for Making Dimethyl Ether by Reactive-Distillation - Disclosed is a method for making dimethyl ether by reactive distillation. The method provides a reactive distillation tower with a top, a bottom, and rectification, reaction and stripping zones defined therein. The top of the reactive distillation tower is retained at 25° C. to 40° C. while the bottom of the reactive distillation tower is retained at 84.6° C. to 170° C. Each of the rectification, reaction and stripping zones includes several sieving trays. The reaction zone of the reactive distillation tower is filled with catalyst. The pressure in the reactive distillation tower is lower than 8.0 bars. Methanol is introduced into the reactive distillation tower so that the methanol travels from the reaction zone toward the bottom for contact with the catalyst to provide a top stream and a bottom stream. The top stream includes dimethyl ether. The bottom stream includes water and a remaining portion of the methanol. Finally, the dimethyl ether is collected in the top of the reactive distillation tower. The purity of the collected dimethyl ether is higher than 99%. | 2012-09-13 |
20120232312 | PROCESS FOR CONVERTING GLYCERIN INTO PROPYLENE GLYCOL - A process to convert glycerin into propylene glycol and purifying the produced propylene glycol is described. The glycerin-based propylene glycol production requires only one process step compared to petroleum/natural gas-based propylene glycol production requires multiple process steps, and thus represents a cost savings. | 2012-09-13 |
20120232313 | METHOD OF MAKING ALCOHOLS - Methods and systems for the synthesis of alcohol are described herein. The methods and systems incorporate the novel use of a high shear device to promote dispersion and solubility of olefins in water. The high shear device may allow for lower reaction temperatures and pressures and may also reduce reaction time. In an embodiment, a method of making an alcohol comprises introducing an olefin into a water stream to form a gas-liquid stream. The method further comprises flowing the gas-liquid stream through a high shear device so as to form a dispersion with gas bubbles having a mean diameter less than about 1 micron. In addition, the method comprises contacting the gas-liquid stream with a catalyst in a reactor to hydrate the olefin gas and form an alcohol. | 2012-09-13 |
20120232314 | CONVERSION OF BUTANOL TO A REACTION PRODUCT COMPRISING 2-ETHYLHEXANOL USING HYDROXYAPATITE CATALYSTS - Catalytic processes to produce a reaction product comprising 2-ethylhexanol by contacting a reactant comprising 1-butanol with a catalyst composition under suitable reaction conditions are provided. The catalyst composition may comprise a hydroxyapatite of the Formula (M | 2012-09-13 |
20120232315 | Vapor Compression Steam Stripping - The invention provides systems and methods for the pre-concentration of a target molecule from feed solution comprising a low concentration of the target molecule. | 2012-09-13 |
20120232316 | CONVERSION OF 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE TO 2,3,3,3-TETRAFLUOROPROPENE - Described is a method for producing fluoropropenes of formula CF | 2012-09-13 |
20120232317 | CONVERSION OF 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE TO 2,3,3,3-TETRAFLUOROPROPENE - Described is a method for producing fluoropropenes of formula CF | 2012-09-13 |
20120232318 | Method for operating plant for producing mixed-gas hydrate - The operation of a plant for producing a gas hydrate is stabilized by making the gas phase within a downstream step have the same equilibrium composition as that of the gas phase within a generation step. The gas phase within a mixed-gas hydrate generation step is circulated to the gas phase within a downstream step located downstream of the mixed-gas hydrate generation step, and the gas phase within each step is thereby made to have the same equilibrium composition as that of the gas phase within the generation step. | 2012-09-13 |
20120232319 | Process and System for the Production of Isoprene - Disclosed herein is a process for producing isoprene that includes reacting a mixed C | 2012-09-13 |
20120232320 | METHOD OF PRODUCING CARRIER FOR CATALYST FOR OXIDATIVE DEHYDROGENATION OF N-BUTANE, METHOD OF PRODUCING CARRIER-SUPPORTED MAGNESIUM ORTHOVANADATE CATALYST, AND METHOD OF PRODUCING N-BUTENE AND 1,3-BUTADIENE USING SAID CATALYST - A method of producing a carrier used for a catalyst for oxidative dehydrogenation of n-butane; a method of producing a magnesium orthovanadate catalyst supported by the carrier; and a method of producing n-butene and 1,3-butadiene using the catalyst are described. | 2012-09-13 |
20120232321 | METHOD FOR SYNTHESIS OF 1-DECENE OLIGOMER - A method for synthesis of 1-decene oligomer is provided, wherein 1-decene is polymerized at 80-120° C., 0.8-1.4 MPa in the presence of aluminum trichloride catalyst supported on gamma-alumina and n-hexane solvent where the volume ratio of 1-decene to n-hexane is 3:8-4:1. The catalyst is treated as follows: impregnating gamma-alumina carrier in 0.5-2.0 mol of hydrochloric acid, sulfuric acid, nitric acid or mixtures thereof, then vacuum drying at 80-100° C. and calcining at 400-800° C.; dissolving 5-10 g of anhydrous aluminum trichloride in 100 ml of tetrachloromethane, trichloromethane or dichloromethane solvent; adding the obtained solution into 10-20 g of activated alumina carrier and obtaining the catalyst after vacuum drying. The conversion rate of 1-decene is 50 wt % or more. The oligomer has a kinematic viscosity at 40° C. of 6.0-25 mm2/s and a viscosity index of 160-262. | 2012-09-13 |
20120232322 | DESULPHURISATION PROCESS - A process for desulphurising hydrocarbons includes the steps of
| 2012-09-13 |
20120232323 | Engineered quartzification of asbestos for remediation, detoxification and containment, and for production of solid-surfacing and decorative uses - This invention pertains to a method for remediating, detoxifying and containing various types of asbestos fibers and asbestos containing materials, such as crocidolite (and other forms of Riebeckite), and tremolite. The end-product of the method may be reclaimed or recycled as useable surfacing, structural and decorative materials. In some embodiments of the invention some end-products of the process may be used as a synthetic gemstone, counter-surfacing material cutting tool, resin for manufacture of furniture products, while others may be used to reclaim natural sand. In one embodiment of this invention crocidolite or other forms of reibeckite or tremolite asbestos debris in loose form or as a component of asbestos cement or other asbestos containing products is converted to a form of engineered quartz, yielding as a synthetic form of the gemstone Tiger's Eye or Hawk's eye. This end-product bears unique and enhanced aesthetic qualities over other types of engineered quartz, called chatoyancy (an optical effect that arises either from the fibrous structure of a material or from fibrous inclusions or cavities and is sometimes likened to the sheen off a spool of silk). The end product therefore achieves luminous more natural-looking effect, while retaining the other desirable features of engineered quartz, such as strength, imperviousness to heat, and resistance to acids and microbial contamination, and reduces the need for the addition of decorative resinous materials which diminish the endurance features of the material. | 2012-09-13 |
20120232324 | Device And Method For 3D Dose Tracking In Radiation Therapy - The present invention relates to a device and method for verification of the quality of a radiation beam in conformal radiation therapy, and in particular for IMRT (Intensity Modulated Radiation Therapy) applications. The actual 3D dose distribution in the patient is tracked during the course of the entire treatment by reconstructing the photon fluences from measured 2D detector responses during irradiation in conjunction with updated patient images. | 2012-09-13 |
20120232325 | RADIOACTIVE BONE CEMENT - Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement. | 2012-09-13 |
20120232326 | LUMENAL REMODELLING DEVICE AND METHODS - A device and method suitable for remodelling the internal surface of a hollow vessel at least partially occluded by a mass is provided. The device comprises an elongate body having a distal end and a proximal end, the distal end comprising a tip portion located at the distal terminus of the body, and at least one heating element located proximally to the tip portion within the distal end. The at least one heating element is configured to be greater in dimension proximally than distally and thereby tapers towards the distal end. Furthermore, the at least one heating element is arranged so that it can be deployed outwardly from the body of the device and in so doing exert an expansion force on the hollow vessel. The at least one heating element is capable of delivering sufficient energy to remodel the internal surface, and if necessary caused localised ablation, of the hollow vessel without inducing closure of the hollow vessel. | 2012-09-13 |
20120232327 | METHOD OF TREATING DEPRESSION, MOOD DISORDERS AND ANXIETY DISORDERS USING NEUROMODULATION - The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety. | 2012-09-13 |
20120232328 | DRUG ACTIVATION SYSTEM - The present invention discloses a drug activator carrier comprising: a) particles having a metallic or metallic oxide core prepared from a paramagnetic material, said metallic core being coated with a coating material selected from polymer, metal or metal oxide; b) a biological material, having reductase activity, bound onto the metal coating the particles of step a), and wherein said biological material is capable of activating non-toxic pro-drugs into active and toxic drugs suitable for treating a disease; said drug activator carrier allowing targeted delivery of the toxic drug. | 2012-09-13 |
20120232329 | MAGNETIC-BASED METHODS FOR TREATING VESSEL OBSTRUCTIONS - Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. | 2012-09-13 |
20120232330 | Device for Administering Drugs and for Influencing the Effects of Drugs - A device has a voltage source, an electric conductor connected to an electric pole of the voltage source and acting as an electrode, and a substrate arranged in an electromagnetic field which is formed in the vicinity of the electric conductor when the voltage source is active. The substrate is used to receive drugs. | 2012-09-13 |
20120232331 | THERAPEUTIC AND SURGICAL TREATMENT METHOD FOR PROVIDING CARDIOPULMONARY AND CIRCULATORY ASSIST DEVICE - The present disclosure relates to a therapeutic method for improving the hemodynamics, the overall microcirculation in organs, and the restoration and preservation of deficient endothelial function in a patient, the method includes maintaining blood circulation in the patient's veins and arteries and temporarily relieving the heart of its pumping function. Relief may be accomplished by increasing the preload of the right ventricle so as to improve oxygenation of the myocardium and its contractility, reducing and diffusing regular pulsations in the proximity of the aortic root so as to improve the hemodynamics of the left ventricle of the heart, and/or mechanically stimulating the endothelium by shear forces so as to reduce systemic and pulmonary afterload. | 2012-09-13 |
20120232332 | Hearing Aid Apparatus and Method - An apparatus for imparting low amplitude vibrations to at least one tooth in a human head having a cochlea to facilitate hearing via a dental bone conduction pathway includes an extraoral transmitter, a band at least substantially surrounding and adhesively secured to at least one tooth, and a receiver assembly. The transmitter is configured to detect ambient sounds, and to generate and wirelessly transmit audio signals corresponding to the detected ambient sounds. The receiver assembly is removably coupleable to the band and configured to receive the audio signals from the transmitter, and to transduce the audio signals into vibrations that are conducted to the cochlea via the dental bone conduction pathway. | 2012-09-13 |
20120232333 | Adaptive Cancellation System For Implantable Hearing Instruments - The invention is directed to an implanted microphone having reduced sensitivity to vibration. In this regard, the microphone differentiates between the desirable and undesirable vibration by utilizing at least one motion sensor to produce a motion signal when an implanted microphone is in motion. This motion signal is used to yield a microphone output signal that is less vibration sensitive. In a first arrangement, the motion signal may be processed with an output of the implantable microphone transducer to provide an audio signal that is less vibration-sensitive than the microphone output alone. Specifically, the motion signal may be scaled to match the motion component of the microphone output such that upon removal of the motion signal from the microphone output, the remaining signal is an acoustic signal. | 2012-09-13 |
20120232334 | IMPLANT FOR HERNIA REPAIR - A hernia repair implant includes a first layer for facing a body structure having a hernia defect to cover the defect while promoting tissue growth into the first layer from the body structure. The implant also includes a second layer opposed to the first layer and made of anti-adhesion material to prevent growth of tissue into the second layer from body structures contacting the second layer. Furthermore, the implant includes at least one engagement strap connected to the first layer and extending therefrom to terminate at a free end. The engagement strap defines opposed thin edges and opposed flat surfaces extending between the edges. At least one barb extends from at least one edge and/or at least one flat surface of the strap and is configured to impede motion of the strap in only a single direction. | 2012-09-13 |
20120232336 | ENDOSCOPE-HOLDING DEVICE AND ENDOSCOPIC SYSTEM - An endoscope holding device includes an insertion part that is long and holds the distal end part of an endoscope so as to freely protrude and retract; a distal end face that specifies a protruding direction of the endoscope, and is formed at the distal end of the insertion part, a displacement part which has a displacement face that is curved from the distal end toward a proximal end and provided at a position apart from the distal end face in order to displace living body tissue in front of the insertion part to secure a space for operating the distal end part of the endoscope protruded from the distal end face to curve; and a fixing portion that fixes the displacement part and the insertion part such that the distal end side of the displacement face intersects a direction orthogonal to the distal end face. | 2012-09-13 |
20120232337 | SOLENOID SYSTEM FOR MAGNETICALLY GUIDED CAPSULE ENDOSCOPY - A solenoid system for magnetically guided capsule endoscopy, has the following components arranged under a patient table which defines a flat plane: a central coil with normal direction being perpendicular to the flat plane, and four coil pairs arranged in the form of a cross around the central coil with respect to the flat plane. Each pair includes two single coils, the normal directions of which are parallel to the flat plane and offset by 90 degrees in relation to each other. | 2012-09-13 |
20120232338 | SURGICAL INSTRUMENT WITH DETACHABLE TIP - An endoscopic hand instrument includes a tubular member having a throughbore extending between a first open end and a second open end, the throughbore including a first portion having a first inner diameter and a second portion having a second inner diameter, a collet member received within the throughbore, the collet member including at least two biasable arm members, the collet member being biased such that the two arm members extend radially outward into the first portion of the throughbore, the two arm members including an area defining an aperture, and a tip assembly having an engagement member, the engagement member being received between the two arm members and into the aperture, the tip assembly engaging the tubular member so as to force the two arm members into the second portion of the throughbore such that the two arm members are prevented from extending radially outward. | 2012-09-13 |
20120232339 | SURGICAL DEVICE AND ACCESSORIES - The present invention relates to a device developed for surgical interventions comprising (i) an inner end ( | 2012-09-13 |
20120232340 | MULTI CAMERA ENDOSCOPE HAVING A SIDE SERVICE CHANNEL - There is provided herein an endoscope assembly comprising at least one front-pointing camera and at least one front illuminator associated therewith, at least one side-pointing camera and at least one of side illuminator associated therewith, a front working channel configured for insertion of a medical tool and a side service channel configured for insertion of a medical tool. | 2012-09-13 |
20120232341 | FLUID EJECTION DEVICE - A fluid ejection device includes a fluid chamber configured to store fluid, a nozzle configured to eject the fluid stored in the fluid chamber, a fluid supply channel connected to the fluid chamber and configured to supply the fluid to the fluid chamber, an air bubbles generating member configured to generate air bubbles in the fluid chamber, and a partitioning wall portion configured to separate the fluid chamber and the fluid supply channel, support the air bubbles generating member. The partitioning wall portion include at least one hole, communicating the fluid chamber and the fluid supply channel. The hole is configured to inhibit backflow during ejection of a jet pulse. | 2012-09-13 |
20120232342 | DISPOSABLE AND REUSABLE COMLEX SHAPED SEE-THROUGH ENDOSCOPE - Transparent domes useful for covering at least a lens located on a scope's distal face, taking the form of a single layer membrane affixed to the distal end of the scope, a solid cap attachable to and detachable from the distal end of the scope, or an inflatable and deflatable balloon having an exterior wall for contacting at least the lens at the scope's distal face. Methods for performing diagnostic or diagnostic and therapeutic procedures within bodily cavities including collapsed intestines using transparent domes and scopes. | 2012-09-13 |
20120232343 | MULTI CAMERA ENDOSCOPE ASSEMBLY HAVING MULTIPLE WORKING CHANNELS - There is provided herein an endoscope assembly, the assembly comprising at least one front-pointing camera and at least one front illuminator associated therewith, at least one side-pointing camera and at least one of side illuminator associated therewith, a first front working channel configured for insertion of a medical tool and a second front working channel configured for insertion of a medical tool. | 2012-09-13 |
20120232344 | CONTROL SIGNAL TRANSMITTING APPARATUS - A magnetic field generating apparatus is the magnetic field generating apparatus that transmits a control signal by a magnetic field to a capsule endoscope that performs control of start and stop according to the control signal. The magnetic field generating apparatus includes a housing including a storing section in which the capsule endoscope is arranged, a magnetic field generating section that generates the magnetic field, and a shield section that shields a leakage electromagnetic field leaking to an area other than the storing section in the magnetic field generated by the magnetic field generating section. | 2012-09-13 |
20120232345 | CAMERA ASSEMBLY FOR MEDICAL PROBES - There is provided herein a camera assembly for use with a medical probe, such as an endoscope, the assembly comprising a main body configured to be mounted on an endoscope tip section, wherein said main body comprises at least one camera and at least one illumination source. | 2012-09-13 |
20120232346 | INSERTION DEVICE AND ENDOSCOPE - An insertion device and an endoscope which are inserted and extracted through a small incision and have multiple functions. A device body has grip forceps as a treatment means. A first folding back section and a second folding back section are provided at a distal portion of the device body such that the first and second folding back sections are aligned in a row in the longitudinal direction of the device body. The first folding back section and the second folding back section respectively have image obtaining means. An operation means can move the first folding back section to a folded back position in which the first folding back section is folded back relative to the second folding back section, and can also move the second folding back section to a position in which the second folding back section is folded back relative to the device body. | 2012-09-13 |
20120232347 | INSERTION ASSISTING TOOL FOR ENDOSCOPE - An insertion assisting tool for an endoscope into which an insertion section of the endoscope is inserted from a base end portion side. The insertion assisting tool may include a fluid sealing device which seals a space between a base end part of the insertion assisting tool and the endoscope insertion section, the space being formed while the insertion section of the endoscope is inserted into the base end portion side. | 2012-09-13 |
20120232348 | Disposable Medical Fiber Optic Light Guide Tube - A disposable attachment to a medical inspection or speculum device is disclosed that improves control of a fiber optic light source utilized in conjunction with the medical device to provide illumination within an internal body cavity. The attachment comprises a hollow guide tube and support having an attachment mechanism, wherein the attachment is adapted to affix to a medical device while the guide tube allows the fiber optic light to be fed therethrough and into the body cavity of interest. The guide tube provides physicians with a readily attachable and disposable alternative to existing methods of handling light sources, which often require diligent guidance and sterilization after each patient. In use, the device allows physicians to accurately inspect and diagnose conditions within a cavity by providing a stable light source to an existing instrument, whereafter the guide tube may be removed and discarded, and further the light may remain sterile. | 2012-09-13 |
20120232349 | Apparatus And Method For Enlarging An Incision - A retraction system and method are provided for retracting tissues surrounding a surgical site. In one aspect, a method including engaging slide connections between a guide dilator and a plurality of tissue engaging members and sequentially enlarging an incision using the guide dilator and the plurality of tissue engaging members. In another aspect, a method of inserting a plurality of tissue engaging members into an incision including fixing tip portions of the plurality of tissue engaging members in an insertion configuration, advancing the tip portions into an incision, and restricting movement of the tip portions away from the insertion configuration. A guide dilator system comprising an elongate body, a plurality of tissue engaging members, and slide connections between the elongate body and the tissue engaging members is also provided. | 2012-09-13 |
20120232350 | RETRACTOR BLADE INCLUDING A FLEXIBLE MEMBER FOR ANCHORAGE ENGAGEMENT - A retractor blade for retracting soft tissues during surgery, the blade having a blade body having a first proximal end and a second distal end, the first end including a structure to allow connection of the blade body to a blade support member; a formation at its distal end which is capable of releasably engaging a second co-operating retractor blade; and a structure to engage the retractor blade to an anchor. | 2012-09-13 |
20120232351 | IRIS RETRACTOR - An iris retractor ( | 2012-09-13 |
20120232352 | VAGINAL DILATOR HAVING SIDE BLADES OR HAVING UPPER AND LOWER BLADES COMPRISING ACCESSORIAL BLADES - A vaginal dilator having side blades or having upper and lower blades comprising accessorial blades includes an upper blade ( | 2012-09-13 |
20120232353 | SURGICAL RETRACTOR AND RELATED METHODS - A surgical retractor includes a base defining an open area therein to correspond with a surgical incision in a body. The base has an inner wall facing the open area and an outer wall facing away from the open area. A plurality of channels extend through the base between the inner and outer walls, and at least one of the channels is at an angle offset from normal to the inner wall where the at least one channel intersects the inner wall. A respective retractor arm is carried within each of the channels for retracting the body to open the surgical incision. In a surgical method, such as a thyroidectomy, a base is positioned so that the open area corresponds with a surgical incision in a body. Respective retractor arms carried within each of the channels are moved to retract the body to open the surgical incision. | 2012-09-13 |
20120232354 | OPTICAL SENSOR SYSTEM AND MEASUREMENT METHOD - A medical device including an optical sensor is configured to measure an optical signal by integrating a current induced on a light detector of the optical sensor to obtain a voltage signal. The voltage signal is compared to a threshold. Responsive to the voltage signal reaching the threshold, an optical sensor control parameter is adjusted. The optical sensor is operated to produce the voltage signal using the adjusted control parameter. | 2012-09-13 |
20120232355 | Automated Caregiving Device with Prompting Based on Caregiver Progress - A device for assisting a caregiver in delivering therapy to a patient, the device comprising a user interface configured to deliver prompts to a caregiver to assist the caregiver in delivering therapy to a patient; at least one sensor configured to detect the caregiver's progress in delivering the therapy, wherein the sensor is other than an electrode in an electrical contact with the body; a memory in which a plurality of different prompts are stored; a processor configured to determine which of the different prompts should be selected for delivery based on the progress detected by the sensor. | 2012-09-13 |
20120232356 | UMBILICAL PROBE SYSTEM - An umbilical probe sensing system is described which includes an automated system for accurately obtaining physiological information from an infant in real time. The system may also automatically guide a healthcare provider with a recommended course of treatment for infant resuscitation based on the detected and monitored physiological data. Moreover, the automated system may also provide a real time record of the infant's physiological parameters and resuscitation treatment performed by a healthcare team. | 2012-09-13 |
20120232357 | UMBILICAL PROBE SYSTEM - An umbilical probe sensing system is described which includes an automated system for accurately obtaining physiological information from an infant in real time. The system may also automatically guide a healthcare provider with a recommended course of treatment for infant resuscitation based on the detected and monitored physiological data. Moreover, the automated system may also provide a real time record of the infant's physiological parameters and resuscitation treatment performed by a healthcare team. | 2012-09-13 |
20120232358 | UMBILICAL PROBE MEASUREMENT SYSTEMS - An umbilical probe sensing system is described which includes an automated system for accurately obtaining physiological information from an infant in real time. The system may also automatically guide a healthcare provider with a recommended course of treatment for infant resuscitation based on the detected and monitored physiological data. Moreover, the automated system may also provide a real time record of the infant's physiological parameters and resuscitation treatment performed by a healthcare team. | 2012-09-13 |