25th week of 2010 patent applcation highlights part 55 |
Patent application number | Title | Published |
20100159495 | PROSECC AN MEANS FOR ENZYMATIC DETERMINATION OF ACETATE - The invention relates to a method and means for the enzymatic determination of acetate. The method according to the invention facilitates for the first time reflectometric detection by means of a test strip. | 2010-06-24 |
20100159496 | EVALUATION METHOD FOR PHOTOSYNTHESIS SAMPLE, EVALUATION SYSTEM FOR PHOTOSYNTHESIS SAMPLE, AND EVALUATION PROGRAM FOR PHOTOSYNTHESIS SAMPLE - An object of the present invention is to appropriately and easily evaluate a photosynthetic function of a photosynthetic sample contained in an evaluation sample. | 2010-06-24 |
20100159497 | Binned Micro-Vessel Density Methods and Apparatus - In one aspect, a method of obtaining micro-vessel density (MVD) measurements from an image of biological vasculature containing a plurality of vessels is provided. The method comprises acts of analyzing a region of interest of the image for each of a plurality of bins, each of the plurality of bins associated with a predetermined range of vessel sizes, the act of analyzing the region of interest including determining which of the plurality of bins that portions of any vessel subject matter identified in the region of interest belong based on a size associated with the respective portions of the vessel subject matter, and associating each portion of the vessel subject matter with the corresponding one of the plurality of bins to which the portion belongs, and computing at least one measurement for each of the plurality of bins, the at least one measurement related to the MVD of the portions of vessel subject matter associated with the respective bin. | 2010-06-24 |
20100159498 | BLOOD ANALYZER WITH A BLOOD CELL SEDIMENTATION CONTROL MECHANISM AND METHOD OF USE - A blood analyzer having a blood cell sedimentation control mechanism is disclosed, which includes a cassette receiving interface including a cassette compartment and a blood sensor operable to detect a presence of blood in a disposable cassette removably disposed within the cassette compartment; a system control electrically connected to the blood sensor, and a blood measurement assembly connected to the system control and adapted to connect with the disposable cassette. The system control includes a time recording mechanism and a predetermined sedimentation time control criterion. Further disclosed is a method of controlling blood cell sedimentation during sample preparation process on the blood analyzer. | 2010-06-24 |
20100159499 | NANOPARTICULATE CELL CULTURE SURFACE - A cell culture article including a substrate having nanoparticles on the substrate surface, the nanoparticle including:
| 2010-06-24 |
20100159500 | Method for determining the haemolysis of a blood sample and device - The invention relates to a method for determining the haemolysis of a blood sample during which the haemolysis progress is determined, wherein the method comprises the steps of irradiating measuring light which is radiated from a measuring light source on the blood sample during haemolysis; detecting measuring light values at several measuring points of time for measuring light transmitted through and/or reflected by the blood sample by a detector device; comparing several of the measuring light values for different measuring points of time and determining a measure for the haemolysis progress by an evaluation device by forming a time-dependent course for the measuring light values from the detected measuring light values, and determining for the time-dependent course at least section-wise a gradient in an assigned measuring curve as a comparative measure for the comparison of the measuring light values at the different measuring points of time; and determining the conclusion of the haemolysis when the gradient within a selectable measurement accuracy, after a measuring period in which the gradient is different from zero, falls to a minimum going down to zero. Another aspect of the invention relates to a device for the determination of the haemolysis of a blood sample. | 2010-06-24 |
20100159501 | METHOD FOR QUANTIFICATION OF CELLULAR SPHINGOLIPIDS - A method is provided for quantifying endogenous sphingolipids in a biological system. The method includes preparing one or more isotope labeled amino acids; introducing the isotope labeled amino acids into a biological system; extracting and separating a sphingolipid-containing fraction from the biological system; and quantifying the amount of endogenous sphingolipids in the biological system. The isotope-labeled amino acid may include a non-essential amino acid, and the method may further include adding an amino acid synthesis inhibitor into the biological system. Systems and kits for quantifying endogenous sphingolipids also are disclosed. | 2010-06-24 |
20100159502 | METHOD AND APPARATUS FOR ENVIRONMENTAL MONITORING AND BIOPROSPECTING - A method for environmental monitoring and bioprospecting includes the steps of: (a) utilizing a testing device having: (i) a container having a fluid inlet and outlet, (ii) a plurality of capillary microcosms situated within the container, each of these capillaries having an inlet and outlet that are configured so as to allow for fluid flow through the capillaries, each of these capillaries further having a means for covering its inlet and outlet so as to prevent flow through the capillary, (iii) a pump connected to the container outlet, the pump being configured so as to draw fluid from the surrounding environment into the container's inlet and through the capillaries, (iv) connected to the outlet of the container, a means for collecting the flow through the container, and (v) a check valve connected downstream of the container to prevent the backflow of fluid into the container, (b) adding specified test substances to the device's capillaries, wherein these substances are to be analyzed for their ability to accelerate a specified biotransformation process in the subject environment, (c) locating this device in this environment and opening the capillary covering means so as to allow fluid from the surrounding environment to flow though the container and capillaries, (d) leaving the device in situ for a temporal duration sufficient to incubate phenomena occurring within the capillary microcosms, (e) retrieving the testing device, and (f) analyzing phenomena occurring with the capillary microcosms using automated analysis schemes and commercially available robotics. | 2010-06-24 |
20100159503 | ENHANCED PROCESSES FOR DRUG TESTING AND SCREENING USING TISSUE SAMPLES - A method for testing human tissue in a testing system is more effective than conventional cell culture systems and functions by treating the human tissue slice system's samples with at least one compound and observing the effect on the human tissue slices resident therein, or cells, tissue samples or other derivatives from the testing process. | 2010-06-24 |
20100159504 | Integrated Microbial Collector - A system for real-time sizing of fluid-borne particles is disclosed. The system further determines, in real time, whether the detected particles are biological or non-biological. As the fluid is being tested, it is exposed to a microbe collection filter which is cultured to determine the type of microbes present in the fluid being tested. | 2010-06-24 |
20100159505 | REAL-TIME MONITORING OF AGE PIGMENTS AND FACTORS RELATING TO TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES AND APPARATUS - A fluorescent spectroscopic method and apparatus for real time direct detection of transmissible spongiform encephalopathies in central nervous system tissue by monitoring the fluorescence of intrinsic markers in the tissue by illuminating the tissue with UV or visible light having an appropriate wavelength, and the resulting emission spectra is detected and examined in the region from 350 to 650 nm. A higher intensity in this region is indicative of infected tissue. The apparatus and method would not interfere with existing slaughterhouse line speeds or procedures, and could be used on live animals. | 2010-06-24 |
20100159506 | METHODS AND SYSTEMS FOR GENETIC ANALYSIS OF FETAL NUCLEATED RED BLOOD CELLS - Methods for determining genetic status of a fetus from a sample of maternal blood comprise enriching nucleated red blood cells in the sample, including both fetal and maternal nucleated red blood cells. The nucleated red blood cells are then differentiated from all other blood cells in the enriched sample, and the nucleated red blood cells genetically screened to determine the genetic status. The nucleated red blood cells may be differentiated by immobilizing all enriched blood cells on a solid phase and locating the nucleated red blood cells for interrogation. Optionally, the nucleated red blood cells may be sorted and separated from other enriched blood cells in a liquid phase. | 2010-06-24 |
20100159507 | SHREDDER FOR MECHANICAL DISRUPTION BY GENTLE CONTROLLED COMPRESSIVE ROTATION - The systems and techniques of the present invention can also synergistically utilize mechanical disruption processes with the use of high hydrostatic pressure extraction, such as pressure cycling extraction techniques to achieve high yield of difficult to extract sample constituents without generating high shear stress or high temperatures. | 2010-06-24 |
20100159508 | THERMALLY RESPONSIVE MICELLES - The invention provides an amphiphilic copolymer comprising monomer units derived from a first monomer and monomer units derived from a second monomer. The copolymer has at least one hydrophobic endgroup. The first monomer is such that the copolymer is thermally responsive and the second monomer comprises a carboxylic acid or carboxylate group. | 2010-06-24 |
20100159509 | Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase - The present invention relates to methods for increasing hydrolysis of a cellulosic material, comprising: hydrolyzing the cellulosic material with an enzyme composition in the presence of a polypeptide having peroxidase activity. | 2010-06-24 |
20100159510 | TRANSGENIC PLANTS EXPRESSING CIVPS OR INTEIN MODIFIED PROTEINS AND RELATED METHOD - Transgenic plants that express CIVPS or intein modified proteins, compositions of matter comprising them, products of diverse applications made from the transgenic plants, methods to construct the transgenic plants containing CIVPS or intein modified genes, methods to express CIVPS or intein modified proteins in plants, and methods of using the transgenic plants. | 2010-06-24 |
20100159511 | PRODUCTION OF RECOMBINANT SELENOPROTEIN MUTANTS WITH ENHANCED CATALYTIC ACTIVITY - The present invention generally relates to the production of industrially relevant quantities of selenoprotein enzymes in eukaryotic cell cultures. More specifically, the present invention generally relates to the production of such enzymes wherein one or more catalytic cysteine or serine residues are mutagenically replaced by selenocysteine. | 2010-06-24 |
20100159512 | METHOD FOR THE PREPARATION OF RECOMBINANT HUMAN THROMBIN AND FIBRINOGEN - The present invention discloses a novel method for the preparation of recombinant human proteins expressed in human cells. Specifically, the present invention relates to novel methods for the preparation of human recombinant thrombin and human recombinant fibrinogen. Moreover, the method employs serum-free culturing conditions and therefore provides recombinant human proteins expressed in human cells of increased safety to the patient when used in human medical treatments. In addition, the immunogenic response to the recombinant human proteins expressed in human cells may be lower. Human recombinant thrombin is expressed in the human embryonic kidney 293 cell line and the protein can be prepared using two different routes, one starting from a point mutated prothrombin with gla and Kringle 1 and 2 domains, and maintaining these domains during the process; the other one starting with prothrombin (non-mutated), via a prethrombin with a HPC4-Kringle 2 domain and subjecting this prethrombin to a point mutation. Human recombinant fibrinogen is expressed in the human embryonic kidney 293 cell line. | 2010-06-24 |
20100159513 | GENES THAT INCREASE PEPTIDE PRODUCTION - Several endogenous genes have been identified in | 2010-06-24 |
20100159514 | SYSTEM FOR PRODUCTION OF ETHANOL AND CO-PRODUCTS WITH FRACTIONATION OF FEEDSTOCK AND SOLVENT WASHING OF FERMENTATION PRODUCT - A system for the production of ethanol and co-products is provided. The system facilitates an overall reduction in the use of energy, for example, by reducing the mass of wet solids supplied to a distillation system. The system also reduces the amount of energy used to dry the wet solids component of a fermentation product, for example, by increasing the ethanol concentration of the wet solids. The system also facilitates the recovery of co-products including bioproducts and other biochemicals extracted from components of the fermentation product. The solids component of the fermentation product may be dried and constituted into a meal that may be used for animal feed, among other uses. | 2010-06-24 |
20100159515 | OXIDATIVE PRETREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Lignocellulosic biomass comprising lignin is treated by selective extraction and oxidation of lignin using a solvent solution comprising water in combination with at least one Mn(III) salt to produce readily saccharifiable carbohydrate enriched biomass. | 2010-06-24 |
20100159516 | ORGANIC SOLVENT PRETREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Biomass is pretreated using an organic solvent solution under alkaline conditions in the presence of one or more alkylamine and optionally one or more additional nucleophile to fragment and extract lignin. Pretreated biomass is further hydrolyzed with a saccharification enzyme consortium. Fermentable sugars released by saccharification may be utilized for the production of target chemicals by fermentation. | 2010-06-24 |
20100159517 | ORGANIC SOLVENT PRETREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Biomass is pretreated using an organic solvent solution, under alkaline conditions, in the presence of one or more organo-mercaptan and optionally one or more additional nucleophile to fragment and extract lignin. Pretreated biomass is further hydrolyzed with a saccharification enzyme consortium. Fermentable sugars released by saccharification may be utilized for the production of target chemicals by fermentation. | 2010-06-24 |
20100159518 | ORGANIC SOLVENT PRETREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Biomass is pretreated using an organic solvent solution under alkaline conditions in the presence of one of more sulfide (hydrosulfide) salt and optionally one or more additional nucleophile to fragment and extract lignin. Pretreated biomass is further hydrolyzed with a saccharification enzyme consortium. Fermentable sugars released by saccharification may be utilized for the production of target chemicals by fermentation. | 2010-06-24 |
20100159519 | ORGANIC SOLVENT PRETREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Biomass is pretreated using an organic solvent solution under alkaline conditions in the presence of elemental sulfur and optionally one or more alkylamine and/or one or more additional nucleophile to fragment and extract lignin. Pretreated biomass is further hydrolyzed with a saccharification enzyme consortium. Fermentable sugars released by saccharification may be utilized for the production of target chemicals by fermentation. | 2010-06-24 |
20100159520 | ORGANIC SOLVENT PRETREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Biomass is pretreated using an organic solvent solution under alkaline conditions in the presence of ammonia and optionally an additional nucleophile to fragment and extract lignin without loss of hemicellulose. Pretreated biomass is further hydrolyzed with a saccharification enzyme consortium. Fermentable sugars released by saccharification may be utilized for the production of target chemicals by fermentation. | 2010-06-24 |
20100159521 | OZONE TREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Methods for treating lignocellulosic biomass to produce readily saccharifiable carbohydrate-enriched biomass are provided. In one method, lignocellulosic biomass comprising lignin is treated with aqueous ammonia, then contacted with a gas comprising ozone at a temperature of about 0° C. to about 50° C. In another method, lignocellulosic biomass comprising lignin is contacted with a gas comprising ozone at a temperature of about 0° C. to about 50° C., then treated with aqueous ammonia. The readily saccharifiable carbohydrate-enriched biomass may be saccharified with an enzyme consortium to produce fermentable sugars. | 2010-06-24 |
20100159522 | ORGANOSOLV AND OZONE TREATMENT OF BIOMASS TO ENHANCE ENZYMATIC SACCHARIFICATION - Lignocellulosic biomass comprising lignin is treated with a solvent, such as organosolv, under alkaline conditions at elevated temperatures, filtered, then contacted with a gas comprising ozone to produce a readily saccharifiable biomass. | 2010-06-24 |
20100159523 | Coryneform Bacteria Which Produce Chemical Compounds I - The invention relates to coryneform bacteria which have, in addition to at least one copy, present at the natural site (locus), of an open reading frame (ORF), gene or allele which codes for the synthesis of a protein or an RNA, in each case a second, optionally third or fourth copy of this open reading frame (ORF), gene or allele at in each case a second, optionally third or fourth site in a form integrated into the chromosome and processes for the preparation of chemical compounds by fermentation of these bacteria. | 2010-06-24 |
20100159524 | APPARATUS AND METHODS FOR PRODUCING AND USING HIGH-DENSITY CELLS AND PRODUCTS THEREFROM - Disclosed and claimed is apparatus and methods for the growth of cells to high density, products therefrom and uses thereof. Also disclosed and claimed is the use of this method for the growth to high-density insect cells, such as the | 2010-06-24 |
20100159525 | Extranuclear RNA Splicing in Neuronal Dendrites - The present invention relates to methods of synaptic network remodeling by means of extranuclear RNA splicing. The present invention also provides methods of extranuclear RNA splicing, and methods of protein translation based on extranuclear RNA splicing. | 2010-06-24 |
20100159526 | SELECTIVE 5' LIGATION TAGGING OF RNA - The present invention provides novel compositions, kits and methods employing RNA 5′ polyphosphatases, RNA 5′ monophosphatases, capping enzymes, decapping enzymes, nucleic acid pyrophosphatases and RNA ligases, as well as other enzymes, for selective 5′ ligation tagging of desired classes of RNA molecules that differ with respect to particular chemical moieties on their 5′ ends. The 5′tagged RNA molecules can be used for synthesis of tagged first-stand cDNA, double-stranded cDNA, and sense or antisense RNA for a variety of uses. | 2010-06-24 |
20100159527 | Polypeptides Having Nucleic Acid Binding Activity and Compositions and Methods For Nucleic Acid Amplification - Polypeptides having nucleic acid binding activity are provided. Methods of using polypeptides having nucleic acid binding activity are provided. Fusion proteins and methods of using fusion proteins are provided. Fusion proteins comprising a polymerase and a nucleic acid binding polypeptide are provided. Fusion proteins comprising a reverse transcriptase and a nucleic acid binding polypeptide are provided. Methods are provided for amplifying a nucleic acid sequence using a fusion protein comprising a nucleic acid binding polypeptide and a polymerase. Methods are provided for amplifying a nucleic acid sequence using a fusion protein comprising a nucleic acid binding polypeptide and a reverse transcriptase. | 2010-06-24 |
20100159528 | POLYMERASE STABILIZATION - The present invention relates to methods and compositions for providing purified thermostable enzymes, particularly thermostable DNA polymerases, that are free of exogenous detergents. The present invention also provides methods for providing such purified thermostable DNA polymerases to assays in an active form by adding one or more detergents. The present invention further provides compositions and kits comprising purified thermostable DNA polymerases for use in a variety of applications, including amplification and sequencing of nucleic acids. | 2010-06-24 |
20100159529 | DRY COMPOSITION OF REACTION COMPOUNDS WITH STABILIZED POLMERASE - The present invention provides methods to obtain dry compositions of reaction compounds that maintain the biological activity of the compounds upon re-solubilization after a certain storage time. Preferably, the dry composition comprises a polymerase, and the dry composition is usable for polymerase chain reaction (PCR) amplification after re-solubilization. | 2010-06-24 |
20100159530 | COMPOSITIONS AND METHODS TO DETECT CANDIDA ALBICANS NUCLEIC ACID - Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for | 2010-06-24 |
20100159531 | Methods And Solutions For Inhibiting Undesired Cleaving Of Labels - The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses. | 2010-06-24 |
20100159532 | METHOD AND DEVICE FOR PERFORMING A NUCLEIC ACID PREPARATION AND/OR AMPLIFICATION - The invention relates to a method and a device for performing a nucleic acid preparation and/or amplification. | 2010-06-24 |
20100159533 | SIMPLIFIED SAMPLE PREPARATION FOR RNA ANALYSIS - Methods and kits for selective preparing cDNA relatively free of sequences found in rRNA and subcellular RNAs are disclosed. The methods and kits utilize approximately 200 hexamer sequences which target messenger RNA. The methods and kits are useful in preparing samples for sequencing analysis, especially when performing single molecule sequencing by synthesis. | 2010-06-24 |
20100159534 | Recombinant Type II Restriction Endonuclease, NmeAIII, and a Process for Producing the Same - A protein is described that has an amino acid sequence characterized by at least 90% sequence identity with SEQ ID NO: 24, the protein being capable of recognizing a sequence consisting of 5′-GCCGAG-3′ within the double-stranded DNA and cleaving the substrate predominantly at 21/19 nucleotides from the recognition site. A method is also described that utilizes the protein for creating a DNA tag for use as a unique identifier for paired end sequencing of DNA or serial analysis of gene expression. | 2010-06-24 |
20100159535 | METHODS FOR INCREASING HYDROLYSIS OF CELLULOSIC MATERIAL - The present invention relates to methods for pretreating a cellulosic material, methods for degrading or converting a cellulosic material, methods for producing a fermentation product, and methods of fermenting a cellulosic material under anaerobic conditions. | 2010-06-24 |
20100159536 | Methods for increasing hydrolysis of cellulosic material in the presence of cellobiose dehydrogenase - The present invention relates to methods for degrading or converting a cellulosic material, methods for producing a fermentation product, and methods of fermenting a cellulosic material with an enzyme composition comprising one or more (several) cellulolytic enzymes, a cellobiose dehydrogenase, and a polypeptide having cellulolytic enhancing activity. | 2010-06-24 |
20100159537 | ESCHERICHIA COLI STRAINS THAT OVER-PRODUCE L-THREONINE AND PROCESSES FOR THEIR PRODUCTION - The invention relates to novel bacterial strains and constructs as well as methods for production of L-amino acids, including but not limited to L-threonine. Such novel bacterial strains may be characterized by, for instance, | 2010-06-24 |
20100159538 | METHOD FOR THE CHEMOENZYMATIC PRODUCTION OF FATTY ACID ESTERS - A chemoenzymatic process for the production of fatty acid esters comprising partially esterifying one or more fatty acid esters, under mild temperatures with an enzymatic catalyst, and optionally in the presence of one or more inert solvents, with a 1- to 5-fold molar excess of one or more water-containing aliphatic alcohols with boiling points between 60° C. and 120° C., then removing the water and unreacted alcohol(s) from the resulting pre-esterification product, followed by additional esterification up to 99.7%, chemically-catalyzed with, e.g., an acid or tin salt at slightly higher temperatures, optionally using one or more inert solvents, with a 1- to 4-fold molar excess of the same one or more aliphatic alcohols as employed in the preliminary esterification step. | 2010-06-24 |
20100159539 | METHODS AND SYSTEMS FOR PRODUCING BIOFUELS AND BIOENERGY PRODUCTS FROM XENOBIOTIC COMPOUNDS - The present invention provides methods and systems for producing biofuel and bioenergy products using, as starting raw material, xenobiotic materials or compounds. The xenobiotic materials or compounds may originate from industrial or chemical plants, municipal waste, pharmaceutical products, cosmetic and personal care products, or other sources, and may include aliphatic and aromatic hydrocarbons, chlorinated organic solvents and other halogenated hydrocarbons, as well as heteroaromatic compounds. In accordance with the invention, these materials act as a carbon source to support the metabolism of xenobiotic-degrading microorganisms, thereby producing biomass and/or biogas that may be converted to bioenergy products by microbial synthesis. For example, the biomass may be converted to products such as ethanol, methanol, butanol, and methane, among others. The biogas may be converted to hydrogen gas and biodiesel, among others. Thus, the present invention couples the microbial breakdown (decomposition) of xenobiotic materials with the microbial synthesis of biofuel, thereby supplying needed (inexpensive) energy products, while reducing environmental pollution and contamination, and reducing the costs associated with disposal of hazardous waste. | 2010-06-24 |
20100159540 | SYNTHESIS OF RESOLVINS AND INTERMEDIATES, COMPOUNDS PREPARED THEREBY, AND USES THEREOF - Methods are disclosed for the preparation of a new class of lipid mediators known as resolvins, with Resolvin D6 (4,17-dihydroxy-5E,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid) being exemplary. Also disclosed are methods for the efficient synthesis of key intermediates in the preparation of such resolvins, such as isotopically labeled ω-3 fatty acid metabolites, and derivatives and analogs thereof. The invention likewise extends to the intermediates so prepared, and to the resolvins prepared with their use. | 2010-06-24 |
20100159541 | GENE ASSOCIATED WITH FOAM FORMATION OF ACETIC ACID BACTERIUM, ACETIC ACID BACTERIUM BRED BY MODIFYING THE GENE AND METHOD FOR PRODUCING VINEGAR USING THE ACETIC ACID BACTERIUM - The object of the present invention is to provide a method for suppressing foam formation by identifying a gene involved in foam formation during culture of an acetic acid bacterium and reducing or deleting the function of a protein encoded by the gene, a method for more efficiently producing vinegar that contains a high concentration of acetic acid by using an acetic acid bacterium in which foam formation has been suppressed by the above method, and vinegar produced by the production method. An acetic acid bacterium with suppressed foam formation was given by obtaining a gene encoding a protein involved in foam formation during culture of an acetic acid bacterium, then by altering the gene by a modification to reduce or delete the function of a protein involved in foam formation. Further provided is a method for efficiently producing vinegar with a higher concentration of acetic acid with the use of the acetic acid bacterium. | 2010-06-24 |
20100159542 | BACTERIAL CELLS EXHIBITING FORMATE DEHYDROGENASE ACTIVITY FOR THE MANUFACTURE OF SUCCINIC ACID - The present invention relates to a bacterial cell of the genus | 2010-06-24 |
20100159543 | BACTERIAL CELLS HAVING A GLYOXYLATE SHUNT FOR THE MANUFACTURE OF SUCCINIC ACID - The present invention is concerned with bacteria for the production of succinic acid. Specifically, the invention relates to a bacterial cell of the genus | 2010-06-24 |
20100159544 | HOMO-SUCCINIC ACID PRODUCING MICROORGANISM VARIANT AND PROCESS FOR PREPARING SUCCINIC ACID USING THE SAME - The present invention relates to microbial variants producing homo-succinic acid at high yields and a method for producing homo-succinic acid using the same, more particularly, to a microbial variant constructed by disrupting a lactate dehydro-genase-encoding gene (idhA) and an acetate kinase-encoding gene (ackA), as well as a method for producing homo-succinic acid at high concentration, which comprises culturing such variants using glucose as a carbon source in anaerobic conditions. | 2010-06-24 |
20100159545 | METHOD FOR PRODUCTION OF COROSOLIC ACID IN SUSPENSION CULTURE OF PLANT CELLS - The present invention relates to a method of producing corosolic acid by using plant cells that produce corosolic acid. More particularly, the present invention relates to a method of producing corosolic acid by using plant cell suspension cultures comprising the steps of: inducing a callus from a tissue of a plant producing corosolic acid; preparing a cell line capable of being cultured in liquid culture medium from the induced callus; culturing the cell line in a suspension culture; and isolating corosolic acid from the culture solution. The present invention has advantage of maximizing productivity by utilizing two-stage culture, treatment with inducing agent, and high cell-density culture in the suspension culture of plant cells producing corosolic acid. | 2010-06-24 |
20100159546 | METABOLIC ENGINEERING OF YEASTS FOR THE PRODUCTION OF 1-BUTANOL - The present invention provides genetically modified yeast cells, and methods of using those yeast cells, to produce 1-butanol. The yeast cell can be selected from the genera | 2010-06-24 |
20100159547 | METHOD FOR SEPARATING OIL FROM AN OIL CONTAINING MATERIAL, METHOD FOR THE PRODUCTION OF ETHANOL, AND ETHANOL PRODUCTION FACILITY - A method for separating oil from flour includes steps of: separating flour into a first stream comprising coarse flour and a second stream comprising fine flour; combining a first extraction solvent with the first stream and extracting oil from the first stream to provide a first miscella and coarse solids; combining a second extraction solvent with the second stream and extracting oil from the second stream to form a second miscella and fine solids; and recovering oil from the first miscella and the second miscella. Another method that can be used separate from or in combination with the previously described method includes steps of: extracting oil from the oil containing, non-fermented, vegetable material with a water immiscible extraction solvent and forming a mixture; combining the mixture with water and forming an organic phase and a water phase; and separating the organic phase and the water phase to form: the organic phase comprising the water and oil enriched immiscible extraction solvent; and the water phase comprising water and oil depleted, non-fermented, vegetable material. A method for producing ethanol and an ethanol production facilitate are described. | 2010-06-24 |
20100159548 | SYSTEM FOR PRODUCTION OF ETHANOL AND CO-PRODUCTS WITH SOLVENT WASHING OF FERMENTATION PRODUCT - A system for the production of ethanol and co-products is provided. The system facilitates an overall reduction in the use of energy, for example, by reducing the mass of wet solids supplied to a distillation system. The system also reduces the amount of energy used to dry the wet solids component of a fermentation product, for example, by increasing the ethanol concentration of the wet solids. The system also facilitates the recovery of co-products including bioproducts and other biochemicals extracted from components of the fermentation product. The solids component of the fermentation product may be dried and constituted into a meal that may be used for animal feed, among other uses. | 2010-06-24 |
20100159549 | SYSTEM FOR PRODUCTION OF ETHANOL AND CO-PRODUCTS WITH SEPARATION AND SOLVENT WASHING OF FERMENTATION PRODUCT - A system for the production of ethanol and co-products is provided. The system facilitates an overall reduction in the use of energy, for example, by reducing the mass of wet solids supplied to a distillation system. The system also reduces the amount of energy used to dry the wet solids component of a fermentation product, for example, by increasing the ethanol concentration of the wet solids. The system also facilitates the recovery of co-products including bioproducts and other biochemicals extracted from components of the fermentation product. The solids component of the fermentation product may be dried and constituted into a meal that may be used for animal feed, among other uses. | 2010-06-24 |
20100159550 | SYSTEM FOR PRODUCTION OF ETHANOL AND CO-PRODUCTS WITH APPARATUS FOR SOLVENT WASHING OF FERMENTATION PRODUCT - A system for the production of ethanol and co-products is provided. The system facilitates an overall reduction in the use of energy, for example, by reducing the mass of wet solids supplied to a distillation system. The system also reduces the amount of energy used to dry the wet solids component of a fermentation product, for example, by increasing the ethanol concentration of the wet solids. The system also facilitates the recovery of co-products including bioproducts and other biochemicals extracted from components of the fermentation product. The solids component of the fermentation product may be dried and constituted into a meal that may be used for animal feed, among other uses. | 2010-06-24 |
20100159551 | SYSTEM FOR PRODUCTION OF ETHANOL AND CO-PRODUCTS WITH RAW STARCH HYDROLYSIS AND SOLVENT WASHING OF FERMENTATION PRODUCT - A system for the production of ethanol and co-products is provided. The system facilitates an overall reduction in the use of energy, for example, by reducing the mass of wet solids supplied to a distillation system. The system also reduces the amount of energy used to dry the wet solids component of a fermentation product, for example, by increasing the ethanol concentration of the wet solids. The system also facilitates the recovery of co-products including bioproducts and other biochemicals extracted from components of the fermentation product. The solids component of the fermentation product may be dried and constituted into a meal that may be used for animal feed, among other uses. | 2010-06-24 |
20100159552 | PROCESS FOR ALCOHOLIC FERMENTATION OF LIGNOCELLULOSIC BIOMASS - A process for the production of ethanol wherein a hydrolyzed lignocellulosic biomass is fermented in the presence of a stillage residue. The fermentation of cellulosic hydrolysates is improved by adding prior to and/or during fermentation a stillage residue side stream from a corn starch-to-ethanol process as a nutrient source for the yeast organisms used in the fermentation. Stillage residues from the grain dry mill ethanol producing process, including the whole stillage, wet cake, thin stillage, and/or syrup are added to assist as a nitrogen and nutrient source for the fermentive processes. The stillage residue is produced by any grain-to-ethanol process. | 2010-06-24 |
20100159553 | Production of Gasoline From Fermentable Feedstocks - Compositions and methods for forming hexane, and, optionally, gasoline and/or components of a gasoline composition, from fermentable sugars are disclosed. The sugars are fermented using a bacteria or yeast that predominantly forms butyric acid. The butyric acid is subjected to Kolbe or photo-Kolbe electrolysis to form hexane. The hexane can be subjected to catalytic, reforming and/or isomerization steps to form higher octane products, which are or can be included in gasoline compositions. In one aspect, the fermentable sugars are derived from lignocellulosic materials such as wood products, switchgrass, or agricultural wastes. These materials are delignified to form lignin, cellulose and hemicellulose. The cellulose and hemicellulose are depolymerized to form glycose and xylose, either or both of which can be fermented by the bacteria. The lignin can be used to generate heat energy and/or electric energy for use in one or more process steps, such as the fermentation, product isolation, Kolbe electrolysis, catalytic reforming and/or isomerization steps. Alternatively, the lignin can be converted to synthesis gas, which can then be subjected to Fischer-Tropsch synthesis, or converted to methanol and/or ethanol. Thus, the methods described herein can convert biomass to a fuel composition or fuel additive, which can be used in a conventional gasoline engine, unlike traditional fuels such as ethanol or biodiesel. | 2010-06-24 |
20100159554 | BIOFUELS PROCESSES INTEGRATING PHOTOBIOREACTORS WITH ANAEROBIC DIGESTION - In the present invention, integrated processes for producing a biofuel are disclosed. Specifically, processes integrating photobioreactors with anaerobic digestion are disclosed. Anaerobic digestion can convert biomass into a biofuel. However, anaerobic digestion also produces carbon dioxide (CO | 2010-06-24 |
20100159555 | PRODUCTION OF SECONDARY METABOLITES USING CAPILLARY MEMBRANES - The invention provides methods of producing secondary metabolites and under recombinant products oxygen-limited or anaerobic culture conditions. The methods include providing a porous substrate having a first side and a second side and which has a biofilm of microorganisms attached to the first side thereof, and causing a nutrient solution to flow through the biofilm and the substrate in a direction from the first side thereof to the second side thereof under oxygen-limited or anaerobic culture conditions. The microorganisms include | 2010-06-24 |
20100159556 | Method for Manipulating Magnetic Particles in a Liquid Medium - A method of mixing magnetic particles ( | 2010-06-24 |
20100159557 | Pelletization Process to Control Filamentous Fungi Morphology for Enhanced Reactor Rheology Bioproduct Formation - Filamentous fungi are grown in pellet form by culturing the filamentous fungi in liquid culture under one or more of the following conditions: 1) with addition of particulate substrates: 2) using spores which have been stored for a period of time prior to inoculation; and 3) using high spore inoculum concentrations. | 2010-06-24 |
20100159558 | REDUCING BYPRODUCTION OF MALONATES IN A FERMENTATION PROCESS - Described are methods of reducing the amount of byproduct organic acids during fermentation of an organism, based on expression of a heterologous malonyl-CoA synthetase. A polyunsaturated fatty acid [“PUFA”]-producing strain of the oleaginous yeast | 2010-06-24 |
20100159559 | GLOBAL AMPLIFICATION USING RANDOM PRIMING BY A COMPOSITE PRIMER - The invention relates to the field of polynucleotide amplification. More particularly, the invention provides methods, compositions and kits for amplification of (i.e., making multiple copies of) a multiplicity of different polynucleotide template sequences using a randomly primed RNA/DNA composite primer. | 2010-06-24 |
20100159560 | METHOD OF PRODUCING MICROBIAL TRANSGLUTAMINASE - The present invention provides a neutral metalloprotease from actinomycetes which selectively cleaves a pro-structure part of a microbial protransglutaminase and a gene encoding said neutral metalloprotease. An active microbial transglutaminase having the pro-structure part cleaved can be obtained by culturing a microorganism into which a gene encoding the neutral metalloprotease from actinomycetes according to the present invention has been introduced, where by producing the neutral metalloprotease from actinomycetes, and reacting it on a microbial protransglutaminase. | 2010-06-24 |
20100159561 | KITS FOR AMPLIFYING DNA - Kits for amplifying DNA which include a priming oligonucleotide that hybridizes to a 3′-end of a DNA target sequence, a displacer oligonucleotide that hybridizes to a target nucleic acid containing the DNA target sequence at a position upstream from the priming oligonucleotide, and a promoter oligonucleotide that includes a region that hybridizes to a 3′-region of a DNA primer extension product that includes the priming oligonucleotide and a promoter for an RNA polymerase. The priming oligonucleotide does not include an RNA region that hybridizes to the target nucleic acid and is selectively degraded by an enzyme activity when hybridized to the target nucleic acid. The kits do not include a restriction endonuclease and oligonucleotides that include a promoter for an RNA polymerase are all modified to prevent the initiation of DNA synthesis therefrom. | 2010-06-24 |
20100159562 | FUNGUS-INDUCED INFLAMMATION AND EOSINOPHIL DEGRANULATION - This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for assessing eosinophil degranulation, and methods for identifying inhibitors of fungus-induced inflammation and/or eosinophil degranulation are provided. | 2010-06-24 |
20100159563 | Preparation and use of biofilm-degrading, multiple-specificity, hydrolytic enzyme mixtures - The present invention relates to isolated structures containing degradative enzymes produced from a marine organism. The enzymes produced are based on the carbon source upon which the marine organism is growing. The enzymes are found in structures that can be isolated such that the degradative enzymes are easily harvested. | 2010-06-24 |
20100159564 | Protease resistant recombinant bacterial collagenases - The identification of the most sensitive sites of | 2010-06-24 |
20100159565 | Toxin-Eating Bacteria and Bioremediation - Bacteria that can use antibiotics as a carbon source are provided. Methods and bacteria useful for bioremediation are also provided. | 2010-06-24 |
20100159566 | SYSTEMS AND METHODS FOR PRODUCING BIOFUELS AND RELATED MATERIALS - cells (American Type Culture Collection 700394 | 2010-06-24 |
20100159567 | PRESERVATION AND COMPOSITION OF BIOPROCESS ALGAE FOR PRODUCTION OF LIPIDS, SEEDSTOCK, AND FEED - The present invention relates to compositions and uses of a novel | 2010-06-24 |
20100159568 | GORDONIA SIHWENSIS STRAIN AND USES THEREOF - Described herein is a strain of | 2010-06-24 |
20100159569 | PROCESSING BIOMASS - Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy materials, to produce ethanol and/or butanol, e.g., by fermentation. | 2010-06-24 |
20100159570 | Analyte Determination Methods and Devices - The present invention provides methods and apparatuses for analyte detection. | 2010-06-24 |
20100159571 | BIOGAS PLANT FOR METHANIZING BIOMASS HAVING A HIGH SOLIDS FRACTION - A biogas plant for methanizing biomass having a high solids fraction includes a digestion tank system having a plurality of digestion tanks adapted to be closed in a gas- and liquid-tight manner, each of which includes a charging and withdrawing opening for charging with biomass and withdrawing the biomass, a biogas discharge means, a percolate reservoir, a percolate drainage means for discharging percolate from the plurality of digestion tanks and supplying the percolate to the percolate reservoir, a percolate distributing means for distributing the percolate from the percolate reservoir over the biomass in the plurality of digestion tanks, and a percolate regulating means for regulating the percolate level in the plurality of digestion tanks. The percolate reservoir includes a first and a second percolate container, and supplying and discharging of percolate to/from the first and/or the second percolate container takes place with the aid of the percolate regulating means. | 2010-06-24 |
20100159572 | DEVICE AND ASSOCIATED METHOD - A microfluidic device for detecting one or more molecules of interest comprising: a non-conductive substrate; wherein the non-conductive substrate is provided with a plurality of thermally active elements is provided. A method for selectively functionalizing a plurality of thermally active elements is also provided. | 2010-06-24 |
20100159573 | MICROFLUIDIC DILUTION DEVICE - Provided is a microfluidic dilution device that uses capillary force to dilute first and second fluids in a predetermined ratio. The microfluidic dilution device includes a channel plate, a cover plate, fluid chambers, and a confluence chamber. The fluid chambers are filled with first and second fluids in a predetermined ratio. First and second fluids flowing to the confluence chamber are diluted in a predetermined ratio. | 2010-06-24 |
20100159574 | MICROFLUIDIC DEVICE AND MICROFLUIDIC ANALYSIS EQUIPMENT - Provided are a microfluidic device and a microfluidic analysis equipment. The microfluidic device includes guides disposed along both edges, a lower plate including a flow path defined between the guides, and a movable upper plate moved along the guides on the lower plate and having a length less than that the flow path. A fluid flow can be simply accurately controlled by adjusting a position of the movable upper plate. As a result, the fluid can sufficiently react in the detection part and the reaction part. Therefore, effective reaction and detection can be realized using only a small amount of fluid, thereby improving sensitivity. In addition, due to the improved sensitivity, a washing process for removing materials that are not consumed in the reaction can be omitted. Also, the movable upper plate can be manually moved using a user's finger. | 2010-06-24 |
20100159575 | QUANTITATIVE SAMPLER OF PATHOGENS IN EXHALED AIR - A quantitative sampler of pathogens in exhaled air is provided. The quantitative sampler includes an air inputting pipe for a sampled individual to blow exhaled air; a check valve unit for preventing the exhaled air from reversely flowing; an aerosol filtering unit having an aerosol filtering material for collecting aerosol particles in the exhaled air; and an air flow meter for measuring if total accumulated volume of the exhaled air reaches a predetermined sampling volume defined as a concentration denominator of exhaled pathogens. The quantitative sampler can be used to collect the aerosol particles, and then moves the aerosol filtering material out of the aerosol filtering unit followed by separating genetic substances in the aerosol particles from the aerosol filter, so that a real-time qPCR can be reacted by using the genetic substances for obtaining a quantitative concentration of the exhaled pathogens. | 2010-06-24 |
20100159576 | BIOCHIP AND BIOMATERIAL DETECTION APPARATUS - Provided are a biochip and a biomaterial detection apparatus. The biochip includes a substrate, a metal layer, and a dielectric layer. The substrate includes a surface having a plurality of acute parts which are formed by first and second inclined planes. The metal layer is formed on at least one of the first and second inclined planes. The dielectric layer is formed on the metal layer, and capture molecules specifically binding to target molecules which are marked with a fluorescent substance are immobilized to a surface of the dielectric layer. | 2010-06-24 |
20100159577 | AUTOMATIC CULTURE DEVICE, SLIDE VALVE, AND DISPOSABLE CONTAINER - A culture device includes: a housing accommodating therein a preservation container preserving a first solution liquid for cell culture, the housing having an opening for discharging the first solution liquid out of the housing; a cultivation container having an opening, in which the cell culture can be performed; and a slide valve provided between the housing and the cultivation container. The slide valve includes: a slide valve body; a connection hole formed in the slide valve body and capable of connecting the opening of the housing and the opening of the cultivation container; a first lid portion closing one open end of the connection hole; and a second lid portion closing the other open end of the connection hole. The first and second lid portion defines there-between a sealed space in the connection hole. The sealed space is capable of containing therein a second solution liquid for the cell culture. | 2010-06-24 |
20100159578 | Method and system for robotic algae harvest - A Robotic Algae Harvester (RAH) of the present invention works by providing a CO | 2010-06-24 |
20100159579 | PHOTOBIOREACTOR SYSTEMS - The invention provides for photobioreactor systems that can be used for the growth of photoautotrophic organisms. The photobioreactor systems can be scalable and modular, such that the production capacity of a photobioreactor system can be readily increased or decreased. The system may include photobioreactor units or blades that can be operated and maintained through a central control system. | 2010-06-24 |
20100159580 | CELL CULTURE COMPARTMENT UNIT AND ARRAY INCLUDING THE SAME - Provided are a cell culture compartment unit and an array including the same. The cell culture compartment unit includes: a cell culture region and a bio material emission region including a cell culture fluid, which are separated with a porous membrane therebetween; a piezoelectric device on the porous membrane of the cell culture region; a thin layer for cell attachment being on the piezoelectric device and having at least one surface on which cells are attachable; and a first power supply applying a first electric field to the piezoelectric device. | 2010-06-24 |
20100159581 | Adsorbent Filter Media For Removal Of Biological Contaminants In Process Liquids - Adsorbent filter media particularly suited for removal of biological contaminants in process liquids. A porous fixed bed of adsorbent material is formed, using only a granular adsorbent and a water-insoluble thermoplastic binder. The resulting composite filter allows for a higher amount of adsorbent with smaller adsorbent particles than conventional depth filters. Elimination of cellulose fiber, as well as the elimination of the thermoset binder, results in reduced contamination of the process liquid. | 2010-06-24 |
20100159582 | DISPOSABLE MULTIPLEX POLYMERASE CHAIN REACTION (PCR) CHIP AND DEVICE - A polymerase chain reaction (PCR) device including a chip assembly, a plurality of chambers being provided in said chip assembly adapted to hold samples, heating means wherein said chip assembly being located on said heating means whereby said chip assembly is allowed to operatively rotate on said heating means, a rotary wheel aiding said chip rotation and wherein said heating means comprises of plural temperature zones in a manner that on rotation of said chip means said sample chamber is shifted from one temperature zone to another by means of a rotary-linear motion system. | 2010-06-24 |
20100159583 | APPARATUS FOR PRODUCING FEEDS COMPRISING DRIED AND FERMENTED ANIMAL AND PLANT RESIDUES AND DRIED AND FERMENTED FERTILIZERS - In organic waste treatment, initial investment and running costs are suppressed, and inexpensive and good-quality dried and fermented feeds and fertilizers are manufactured from animal and plant residues. The animal and plant residues having been reserved/accumulated in a fermentation tank and generated fermentation heat is emitted/sprayed with air into a space in the fermentation tank and repeatedly circulated within the apparatus so that an evapotranspiration action is efficiently performed, oxygen required for fermentation is uniformly supplied so as to keep a favorable fermentation environment, and an apparatus for producing good-quality dried and fermented feeds and fertilizers is provided. | 2010-06-24 |
20100159584 | METHOD AND APPARATUS FOR OBTAINING ALIQUOT FROM LIQUID-BASED CYTOLOGICAL SAMPLE - Sample vials and methods of processing the sample vials are provided. The sample vial comprises a vial container, a sample collection chamber within the vial container, a vial cap configured to be mated with the vial container to enclose the collection chamber, an aliquot chamber, which may be carried by the vial cap or the vial container, and a valve mechanism for selectively sealing and unsealing the aliquot chamber from the collection chamber. The method may comprise flowing an aliquot of the sample from the collection chamber while the sample within the collection chamber is isolated from an environment exterior to the vial, sealing the aliquot chamber from the collection chamber to isolate the aliquot sample from the remaining sample portion, and transferring at least some of the remaining sample portion from the collection chamber to a microscope slide while the aliquot chamber is sealed from the collection chamber. The method further comprises reserving the slide for cytological screening of the sample, and reserving the aliquot sample for deoxynucleic acid (DNA) testing. | 2010-06-24 |
20100159585 | Suppressor tRNA Transcription in Vertebrate Cells - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA's/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided. | 2010-06-24 |
20100159586 | Hybrid Suppressor tRNA for Vertebrate Cells - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA's/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided. The present invention provides vertebrate cells with translation components, e.g., pairs of orthogonal aminoacyl-tRNA synthetases (O-RSs) and orthogonal tRNA's (O-tRNA's) and individual components thereof, that are used in vertebrate protein biosynthetic machinery to incorporate an unnatural amino acid in a growing polypeptide chain, in a vertebrate cell. | 2010-06-24 |
20100159587 | ANTIBODIES AGAINST HUMAN ANGIOPOIETIN 2 - The present invention relates to antibodies against human Angiopoietin 2 (anti-ANG-2 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 2010-06-24 |
20100159588 | CONDITIONED MEDIA AND METHODS OF MAKING A CONDITIONED MEDIA - A stable and scalable process is provided to manufacture reduced serum umbilical cord tissue-derived (UTC)-conditioned media. The method includes the culture of a UTC under reduced serum conditions. Subsequently, the UTC is washed and grown in serum-free basal media. After approximately 24 hours, the conditioned media is collected, filtered and concentrated by use of an approximately 5 kDa or similar cut-off membrane. | 2010-06-24 |
20100159589 | NESTIN-EXPRESSING HAIR FOLLICLE STEM CELLS - Hair follicle stem cells are isolated by virtue of understanding their location within the hair follicle during telogen phase. | 2010-06-24 |
20100159590 | SYSTEMS AND METHODS FOR ACTIVE MICROFLUIDIC CELL HANDLING - A method and system for providing a cell support system are described. The method and system include providing a first block, a second block coupled to the first block, and a plurality of microfluidic channels. The first block includes a plurality of cell wells therein. The second block includes a plurality of through holes therethrough. The plurality of holes are in fluid communication with at least one corresponding cell well of the plurality of cell wells. The plurality of microfluidic channels are in fluid combination with at least a portion of the plurality of cell wells and are configured to provide an active fluid flow with the portion of the plurality of cell wells. | 2010-06-24 |
20100159591 | METHODS AND COMPOSITIONS CONCERNING siRNA'S AS MEDIATORS OF RNA INTERFERENCE - The present invention concerns an isolated siRNA of from about 5 to about 20 nucleotides that mediates RNA interference. Also disclosed are methods of reducing expression of a target gene in a cell comprising obtaining at least one siRNA of 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 basepairs in length; and delivering the siRNA into the cell. The siRNAs can be chemically synthesized RNA or an analog of a naturally occurring RNA. | 2010-06-24 |
20100159592 | Emulsion compositions - An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system. | 2010-06-24 |
20100159593 | TRANSFECTION REAGENTS - Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: | 2010-06-24 |
20100159594 | SINGLE CHAIN TRIMERS AND USES THEREFOR - Single chain trimer (SCT) molecules are disclosed, comprising an MHC antigen peptide sequence, a β | 2010-06-24 |