24th week of 2012 patent applcation highlights part 45 |
Patent application number | Title | Published |
20120148946 | Color Filter of Liquid Crystal on Silicon Display Device - A color filter of a liquid crystal on silicon (LCOS) display device is disclosed, including a substrate including a plurality of pixel regions wherein each pixel region includes a first color dot, a second color dot and a third color dot; and a first color resist, a second color resist and a third color resist disposed in the first color dot, the second color dot and the third color dot on the substrate, wherein each of the first color resist, the second color resist and the third color resist includes at least one opening. | 2012-06-14 |
20120148947 | DEVELOPER, DEVELOPER CONTAINER, IMAGE FORMING UNIT AND IMAGE FORMING APPARATUS - Disclosed is a developer including at least a toner for developing electrostatic latent images. The toner includes toner base particles each containing at least one binder resin, and external additives for adhering to the outer surfaces of the toner base particles. The toner has a first triboelectric charge obtained by blow-off charge measurement at 20% relative humidity and a temperature of 10° C., and a second triboelectric charge obtained by blow-off charge measurement at 80% relative humidity and a temperature of 28° C. An absolute value of the difference between the first and second triboelectric charges is no larger than 20 μC/g. | 2012-06-14 |
20120148948 | ELECTROSTATIC IMAGE DEVELOPING TONER, ELECTROSTATIC IMAGE DEVELOPER, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS - An electrostatic image developing toner contains a binder resin and at least two different kinds of white pigments, wherein from about 10% by weight to about 30% by weight of the at least two kinds of white pigments is porous titanium oxide having a volume average particle diameter of from about 0.01 μm to about 1 μm, a particle size distribution (volume average particle size distribution index GSDv) of from 1.1 to 1.3 and a BET specific surface area of from about 250 m | 2012-06-14 |
20120148949 | RESIN COMPOSITION FOR PRINTING PLATE - Disclosed is a polymer having excellent solvent resistance which can be produced by using a polycarbonate diol having a repeating unit represented by the formula (1) and/or (2), having a hydroxyl group at both termini, and having a number average molecular weight of from 300 to 50,000: | 2012-06-14 |
20120148950 | TONER PROCESSES UTILIZING WASHING AID - A process for making toner particles is provided. In embodiments, a suitable process includes adding a washing aid agent to toner particles at the time of washing the toner particles prior to their drying and recover. The washing aid agent assist in the removal of ionic species, including surfactants and ions that are part of the emulsion aggregation process, from the resulting toner particles. Utilization of the washing aid agent produces toner particles having improved charging characteristics. | 2012-06-14 |
20120148951 | SOLVENT-FREE BIO-BASED EMULSION - Solvent-free extrusion processes are disclosed that are suitable for forming high bio-based polyester latexes that may be utilized in forming a toner, as well as other commercial products. | 2012-06-14 |
20120148952 | RADIATION-SENSITIVE RESIN COMPOSITION AND COMPOUND - A radiation-sensitive resin composition includes a compound, a resin and a radiation-sensitive acid generator. The compound has a structure in which a group represented by a following formula (1) is bound to a nitrogen atom. The resin has an acid-dissociative dissolution-controlling group and has a property such that alkali solubility of the resin increases by an action of an acid. In the formula (1), Y is a monovalent group having 5 to 20 carbon atoms, and “*” represents a bonding hand with the nitrogen atom. In the formula (i), R | 2012-06-14 |
20120148953 | Resist composition, and method of forming resist pattern - A resist composition including a base component (A) which exhibits changed solubility in a developing solution under the action of acid, and an acid generator component (B) which generates acid upon exposure, wherein the base component (A) contains a polymeric compound (A1) having a structural unit (a5) represented by general formula (a5-1). In formula (a5-1), R represents a hydrogen atom, an alkyl group or a halogenated alkyl group, X represents single bond or divalent linking group, W represents a cyclic alkylene group which may include an oxygen atom at arbitrary position, each of R | 2012-06-14 |
20120148954 | N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION - Disclosed are an N-acyl-β-lactam derivative represented by the following general formula, from which a photoresist composition capable of controlling an acid diffusion length to be short is obtained; a polymer obtained by polymerizing the N-acyl-β-lactam derivative represented by the following general formula as one of starting materials; and a photoresist composition containing the polymer. | 2012-06-14 |
20120148955 | RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND NEW COMPOUND - A resist composition including: a base component (A) which exhibits changed solubility in a developing solution under action of acid; a nitrogen-containing organic compound component (C) containing a compound (C1) represented by general formula (c1) shown below; and an acid generator component (B) which generates acid upon exposure, provided that the compound (C1) is excluded from the acid generator component (B): | 2012-06-14 |
20120148956 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN - A resist composition including a base component (A) which exhibits changed solubility in a developing solution under action of acid, a nitrogen-containing organic compound (C) containing a compound (C1) represented by general formula (c1) shown below and an acid-generator component (B) which generates acid upon exposure (excluding the compound (C1)) (R | 2012-06-14 |
20120148957 | PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM - A pattern forming method includes: (i) forming a film from a chemical amplification resist composition; (ii) exposing the film, so as to form an exposed film; and (iii) developing the exposed film by using an organic solvent-containing developer, wherein the chemical amplification resist composition contains: (A) a resin substantially insoluble in alkali; (B) a compound capable of generating an acid upon irradiation with an actinic ray or radiation; (C) a crosslinking agent; and (D) a solvent, a negative chemical amplification resist composition used in the method, and a resist film formed from the negative chemical amplification resist composition. | 2012-06-14 |
20120148958 | SULFUR-CONTAINING MACROMOLECULES AND METHODS FOR THEIR PREPARATION - A sulfur-containing macromolecule and a method of preparing the sulfur-containing macromolecule comprising a polymerization step are provided, where the sulfur-containing macromolecule contains internal units of formula (I) and the polymerization step is formula (II) wherein n is greater than 1, said precursor comprises alkyne having one or more acetylene groups and thiol having one or more thiol groups; and R is remainder of said thiol excluding said thiol groups, R′ is remainder of said alkyne excluding said acetylene groups, and R and R′ are selected from organic or organometallic groups. | 2012-06-14 |
20120148959 | PATTERN FORMING METHOD - A pattern forming method includes providing a first mask with a first aperture, forming a first transfer pattern on a resist by irradiating a first electron beam through the first aperture, the first transfer pattern extending in a first direction and having a boundary along a circumference thereof, and the first electron beam having a cross section of a first square when emerging from the first aperture, and forming a second transfer pattern on the resist by irradiating a second electron beam through the first aperture, the second transfer pattern extending in the first direction and overlapping a portion the boundary of the first transfer pattern, and the second electron beam having a cross section of a second square when emerging from the first aperture. | 2012-06-14 |
20120148960 | METHOD OF MANUFACTURING PRINTED CIRCUIT BOARD - A method of manufacturing a printed circuit board, including: applying a conductive paste including carbon nanotubes and a photosensitive binder on a bump-forming area of a circuit substrate having a circuit layer for transferring electrical signals; and patterning the conductive paste, thus forming bumps. | 2012-06-14 |
20120148961 | METHOD AND ARRANGEMENT FOR OPTIMISING COMBUSTION CONDITIONS IN A FLUIDISED-BED BOILER - A method and an arrangement for optimising combustion conditions in a fluidised-bed boiler, in which combustion gas is fed at two or more height levels, the first of which is a primary level (P) which is located at the height of a furnace bottom and the second is a secondary level (S) which is located above fuel feed height (F), above which secondary level (S) there can be still other combustion gas feed levels (T, . . . ). At least one combustion gas feed level (P, S, T, . . . ) is fed at different points of the furnace ( | 2012-06-14 |
20120148962 | COMBUSTION CHAMBER AND METHOD FOR SUPPLYING FUEL TO A COMBUSTION CHAMBER - The combustion chamber has a body with nozzles to inject a fuel to be burnt therein. The nozzles define a plurality of groups to be fed in parallel. The nozzles of each group define at least two stages that are differently operated according to the different operating conditions. The combustion chamber also has a manifold for collecting a fuel to be distributed among the groups, a plurality of supply elements distributing the fuel originating from the manifold to each group, for each group, splitters for diverting the fuel coming from the supply elements between the stages. | 2012-06-14 |
20120148963 | Induced-Draft Low Swirl Burner for Low NOx Emissions - A burner for use with an induced draft furnace and which satisfies reduced nitrous oxide (NO | 2012-06-14 |
20120148964 | CYCLONIC BURNER WITH SEPARATION PLATE IN THE COMBUSTION CHAMBER - A method and apparatus for burning fuel are described In a conventional boiler the combustion process produces particles which form a layer of deposits on boiler tubes, thus reducing heat transfer efficiency A fuel burner ( | 2012-06-14 |
20120148965 | TRANSPARENT GEL CANDLE BASE - The present invention relates to transparent gel candle bases that may be used as a base material of transparent candles, to the transparent candles made therefrom, and to methods of making such candle bases and candles. The transparent gel candle bases of the present invention include a hydrocarbon oil and a gelling agent comprising dibutyl lauroyl glutamide and dibutyl ethylhexanoyl glutamide. | 2012-06-14 |
20120148966 | Candle Wick and Wick Clip - A candle wick includes a first portion oriented perpendicular to a second portion to form a candle wick with a plus-shaped configuration. A wick clip includes a first slot oriented perpendicular to a second slot to form a wick clip plus-shaped configuration sized to receive the plus-shaped configuration of the candle wick. The first slot of the wick clip is configured to receive the first portion of the candle wick, and the second slot of the wick clip is configured to receive the second portion of the candle wick. The candle wick and wick clip form a clip assembly. A candle comprises a plus-shaped candle wick held in place by a wick clip. | 2012-06-14 |
20120148967 | CANDLE WICK INCLUDING SLOTTED WICK MEMBERS - A candle wick ( | 2012-06-14 |
20120148968 | CONVEYANCE RACK, METHOD FOR RETAINING METAL RING, AND METHOD FOR HEAT TREATMENT OF METAL RING - Disclosed are a conveyance rack for retaining and conveying resilience-memory metal rings and a method for retaining the metal rings. The conveyance rack is provided with a base and a plurality of retaining shafts which extend parallel to each other, being erected on the base, and which are provided with, on the side walls thereof, a plurality of protrusions abutting on the lower end surfaces of the metal rings. The protrusions abut on the lower end surfaces of the metal rings by point contact. | 2012-06-14 |
20120148969 | Continuous process for drying microcapsules - The invention teaches continuous process for rapidly drying a population of pressure sensitive microcapsules. The process comprises the steps of a) preparing a slurry comprising pressure-sensitive microcapsules dispersed in an aqueous carrier solution and encapsulating a non-solid core material; b) providing a pulse combustor having a means for generating a pulsating flow of hot gases, the pulse combustor having an associated combustion chamber with inlet means for introducing fuel and combustion air to the combustion chamber whereby the combination of the pulse combustor and the combustion chamber generate a pulsating flow of hot gases, the pulse combustor having an outlet means for discharging the pulsating flow of hot gases, and a material feed introduction chamber connected proximate the outlet means of the combustion chamber; c) inputting the slurry of microcapsules into the material feed introduction chamber; d) converting the slurry of microcapsules to dried microcapsules in a drying chamber communicating with the combustion chamber through the outlet means, the drying chamber receiving the microcapsule slurry fed into the material feed introduction chamber and the pulsating flow of hot gases; and, e) collecting in a collection assembly associated with the drying chamber the microcapsules dried in the drying chamber, whereby the collected microcapsules are substantially free of breakage. | 2012-06-14 |
20120148970 | Cushion Comfort Cushion System for use with Orthodontic Protraction Face Masks: The Naomi Pillow - A Cushion Comfort System which improves the comfort and use of an orthodontic protraction face mask appliance. It is comprised of a pair of cushions, one shaped specifically to cover the forehead rest and the other shaped specifically to cover the chin cup. The forehead cushion and chin cup cushion may be used individually for face masks that have only a forehead rest or only a chin cup. The cushions are made of soft, hypoallergenic, colorful fabrics, soft hypoallergenic pillow fill or batting, and elastic ribbons. They are completely removable and washable. Other embodiments are described. | 2012-06-14 |
20120148971 | ORTHODONTIC APPLIANCE - The present invention concerns an orthodontic appliance for accelerating the tooth aligning effect and shortening the treatment period, and has an object to provide an appliance which can bring about higher aligning effect than usual ways by giving vibration to tooth to be aligned to activate bone remodeling of the targeted tooth and the alveolar bone and enhance the shift of the tooth. This appliance includes a vibrating element and a dental mouthpiece having the vibrating element built therein. The provision of the vibrating element in the dental mouthpiece facilitates the application of vibration and handling, and continues the treatment safely even at home. The inner shape of the dental mouthpiece serves aligning treatment as well as acceleration of the effect. | 2012-06-14 |
20120148972 | Low Force Orthodontic Arch Wire Having Blocks for Improved Treatment - Low force orthodontic arch wires ( | 2012-06-14 |
20120148973 | ORTHODONTIC BRACE SYSTEM AND METHOD - An orthodontic brace system includes brackets having a diamond-shaped tie-wing configuration that defines two parallel, horizontal slots, each of which is adapted to receive an archwire. Each slot is angled with respect to the base of the bracket to produce a specific, maximum torque value, and generally, the maximum torque value of the gingival slot is less than the maximum torque value of the incisal slot. The brackets provide multiple force vectors in different directions simultaneously, which decreases the amount of time required for a patient to wear braces, reduces the number of costly and time consuming visits to an orthodontist, and reduces time and effort required of an orthodontist for installation and adjustment of the braces on a per visit basis. | 2012-06-14 |
20120148974 | Orthodontic gripping device - The present invention relates to an orthodontic gripping device having a body made of a superelastic metal alloy, cold worked titanium beta III, or solution heat treated and aged titanium beta III. The body has first and second, spaced apart arm portions connected to each other. Each arm portion includes a jaw portion having an inner, arch wire-gripping, surface. The inner gripping surfaces are disposed opposite one another in spaced relation with a station defined therebetween for receiving the arch wire. At least a portion of the station is sized smaller than the arch wire. The arm portions are resiliently deflectable outwardly away from each other to admit the arch wire into the station. Once seated in the station, the arch wire is tightly held by inner gripping surfaces so as to resist displacement of the gripping device relative to the arch wire. | 2012-06-14 |
20120148975 | METHOD AND APPARATUS FOR REGULATING TOOTH MOVEMENT - A method is provided for regulating tooth movement, comprising extra-orally administering an effective amount of light transdermally to the maxillary or mandibular alveolar bone of a patient in need thereof. The repetitive dosage can be in the range of 24 J/cm to 200 J/cm. The light can have a wavelength in the range of about 585 nm to about 665 nm, or about 815 nm to about 895 nm. Light having a first wavelength can be administered to a first selected region of the alveolar bone, and light having a second wavelength can be administered to a second selected region of the alveolar bone to selectively regulate tooth movement during orthodontic treatment. An apparatus useful for applying light therapy extra-orally is also provided. | 2012-06-14 |
20120148976 | METHODS AND APPARATUSES USEFUL FOR REGULATING BONE REMODELING OR TOOTH MOVEMENT USING LIGHT THERAPY, A FUNCTIONAL APPLIANCE, AND/OR VITAMIN D - Methods are provided for regulating bone remodeling or tooth movement, comprising allowing a functional appliance to exert a force on oral or maxillofacial bone, muscle, or soft tissue, or one or more teeth of a patient in need thereof; and administering an effective amount of light to the oral or maxillofacial bone, muscle, or soft tissue, or one or more teeth, wherein the light is administered before, during, or after the force is exerted. Methods are also provided for regulating bone remodeling, comprising administering an effective amount of vitamin D to an oral or maxillofacial bone, muscle, or soft tissue, or to one or more teeth of a patient in need thereof; and administering an effective amount of light to the oral or maxillofacial bone, muscle, or soft tissue, or to the one or more teeth. Apparatuses useful for providing light therapy and/or vitamin D is also provided. | 2012-06-14 |
20120148977 | DENTAL IMPLANT DETECTOR - A dental implant detector comprising an inductive sensor arranged to detect a position of a dental implant in a jaw within a specified range by applying a magnetic field to the surroundings of the inductive sensor; an ergonomic handle connected to the inductive sensor and arranged to allow positioning the inductive sensor at various positions near the jaw; and a control unit connected to the inductive sensor and arranged to allow defining the specified range by adjusting a strength of the magnetic field, and to indicate detections by the inductive sensor. The dental implant detector is arranged to allow detection of dental implants concealed by bone or gum overgrowth. | 2012-06-14 |
20120148978 | Impression Tray - A dental impression tray having a tray bottom, an inner wall and an outer wall, which together form the dental mold, whereby the inner and/or outer wall, on their side facing away from the tray bottom is provided at least in sections with a resilient, in particular, elastic element consisting of a softer material compared to that of the wall on which it is located, wherein the element is designed as resilient lip that is located opposite of the wall on which lip is located, aligned inclined toward the interior of the dental mold. | 2012-06-14 |
20120148979 | Apparatus For Cleaning A Root Canal System - An endodontic tool is provided to facilitate the removal of the smear layer and to enhance deep lateral cleaning of a root canal system. The tool is comprised of a sonic or ultrasonically driven activator which is made from a strong, flexible, non-metallic, and non-cutting material. The activator can be smooth. A snap-on coupler is adapted to attach the tool to a driver via a snap on action and without the use of tools. The driver will vibrate, sonically or ultrasonically, the flexible activator within a root canal of a tooth. The tool can be provided with fluid passages which allow for irrigating reagents to be delivered through the activator and into the root canal space during endodontic procedures. | 2012-06-14 |
20120148980 | DEVICE FOR DISPENSING A DENTAL MATERIAL - A dispensing device comprises a compartment for receiving a dental material, a piston for extruding the material from the compartment and a spindle drive for moving the piston and the compartment relative to one another. The spindle drive comprises a spindle and a link which are adapted for disengageable engagement with one another, wherein the spindle and the link are operable relative to each other between an engaged position in which the link and the spindle are engaged with one another, and a disengaged position in which the spindle and the link are disengaged from one another. The device may be relatively robust and inexpensive to manufacture, and may facilitate preparation of dental materials for use. | 2012-06-14 |
20120148981 | FILE FOR WORKING ON THE INTERPROXIMAL SPACE IN ORTHODONTICS AS WELL AS IN CONSERVATIVE TREATMENTS AND PROPHYLAXIS OF TEETH AND RELATIVE DEVICE ABLE TO BE CONNECTED TO AN OSCILLATING HANDPIECE - A file for working on the interproximal space in orthodontics as well as in conservative treatments and prophylaxis of teeth comprises a tool-holding structure and an abrasive plate, wherein the tool-holding structure is shaped in an arc and provided at the ends with two tubular portions and wherein the abrasive plate is stably fixed at both of its ends to the tubular portions of the tool-holding structure, wherein the tool-holding structure is symmetrical and overmolded on said abrasive plate. A relative device able to be connected to an oscillating handpiece comprises such a file and a shank for the connection to the handpiece, wherein the shank is removably fixed to the file. | 2012-06-14 |
20120148982 | Oral Implant Placement System and Method - An oral implant system and method. The system includes a positioning tool, a transfer band, a transfer screw, and a transfer drill to provide for accurate placement of a dental implant parallel to other implants and or existing teeth and at predetermined depths. A model is made of the patient's maxilla and mandible. The model is marked for implant position, depth and size. Holes are drilled in the model for implant analogs using the positioning tool. The analogs are installed into the model using the positioning tool and a surveyor. Transfer bands are coupled to the analogs and a surgical stent portion is fabricated. The surgical stent is fitted to the patient's occlusion, secured, and then utilized to accurately drill apertures into the patient's maxilla or mandible. The implants are installed into the apertures and the surgical stent is removed. A final restoration is secured to the implants. | 2012-06-14 |
20120148983 | DENTAL IMPLANT - The present invention relates to a dental implant and to a process for fabricating the dental implant. | 2012-06-14 |
20120148984 | IMPLANTS AND METHODS FOR PERFORMING GINGIVA AND BONE AUGMENTATION AND PRESERVATION - Embodiments described herein are related to fillers that are placed within an extraction site in need of bone augmentation and preservation. The fillers encourage sufficient new bone growth in order that normal jaw bone deterioration following tooth removal is prevented. The fillers create, arrange, and assemble an ideal growth environment for new bone growth to rapidly grow and preserve the original contours of an individual's jaw bone. Further embodiments described herein are related to dental implants that are arranged to provide a scaffold upon which a damaged or missing dental papilla may regrow. The dental implants may include a micro-pattern to facilitate directional cell growth. | 2012-06-14 |
20120148985 | Method for Machining a Dental Prosthesis - A method for machining a dental prosthesis that reduces the likelihood of forming tool failure includes machining a workpiece to form a top surface and a side surface of the dental prosthesis, machining a connector between a proximal end of the dental prosthesis and a proximal end of the workpiece, and machining a bottom surface of the dental prosthesis with a spiral tool path. | 2012-06-14 |
20120148986 | METHOD FOR IDENTIFICATION OF DENTAL CARIES IN POLYCHROMATIC IMAGES - A method for identification of caries, executed at least in part on data processing hardware, obtains an original digital tooth image that has a plurality of color channels and generates an adjusted image by adjusting intensity values of the original digital tooth image to a range between a minimum value and a maximum value, wherein the adjusted image has at least a green channel image Iwgreen, a red channel image Iwred, and a blue channel image Iwblue. One or more tooth regions are segmented from gum and background regions within the adjusted image according to a relationship between two or more of the images Iwgreen, Iwred, and Iwblue to each other. One or more caries lesions is identified according to pixel intensity values from within the one or more segmented tooth regions, and the one or more tooth regions and the displayed and identified caries regions are highlighted. | 2012-06-14 |
20120148987 | Method For Producing Tooth Replacements And Auxiliary Dental Parts - In a method for forming a dental part, a laser beam is guided over a powder layer of biocompatible material. The laser is guided by a computer controlled laser scanning system based on data representing the shape of the cross-section through the shaped body. The powder is substantially melted by the laser beam to form a layer in the shaped body, to build the shaped body entirely from layers of laser-melted material. | 2012-06-14 |
20120148988 | Indirect restoration technology - Dental restorations such as crowns, are made from lithium silicate glass ceramic that is heated and pressed onto a metal substrate, the latter being shaped to an impression or scan of the area of the mouth to receive the restoration. The metal substrate is made from an alloy selected to exhibit a coefficient of thermal expansion which is slightly greater than the CTE of the lithium silicate. In a preferred embodiment, the CTE of the lithium silicate glass ceramic is in the range of 11.5 to 12.5 and the alloy is selected to have a CTE of 12 to 13.5. A palladium tin alloy provides that CTE in the preferred embodiment. | 2012-06-14 |
20120148989 | Recoil emulation device for weapon training - The present invention relates generally to devices that are used to simulate a firearm recoil effect. It is a known fact that the recoil effect of a firearm directly influences quality of marksmanship of a shooter in areas including but not limited to target acquisition and re-acquisition, firing accuracy, psychological anticipation of a shot to be fired, proper grip of a weapon and more. The suggested device is used in a combination with training simulators to enhance the tactical functionality and by so increasing the quality of training. The recoil emulation device mounts on a barrel of any standard handheld firearm including but not limited to all types of machine guns and sniper rifles. It is then connected via a cable to an air compressor, which provides air pressure required to initiate a recoil emulation cycle. The recoil emulation device consists of a cylinder, which holds a metal ball, which travels throughout the cylinder and provides the impact required to cause an upward displacement of a weapon. | 2012-06-14 |
20120148990 | PRACTICE APPARATUS, PRACTICE SYSTEM AND PRACTICE APPARATUS CONTROL METHOD - In one embodiment, a practice includes a display device, a first controller, an input device and a second controller. The first controller, which controls the display device by displaying an input interface image in the first display area of the display device. The second controller, which controls the display device by playback a dynamic image representing a cue event indicating a cue of the operation in the second display area of the display device, or by continuously displaying a plurality of still images including an image related to a cue event. The second controller stops the playback of the dynamic image or the continuous display of the still images during the period from the moment an image related to a cue event is displayed to the moment an operation is input through the input device that is to be carried out by taking the cue event as a cue. | 2012-06-14 |
20120148991 | Detachable Fingergrip Whistle System - A whistle system that enables an official or other user to not only have the whistle in a secure position for quick and easy use while also enabling the user to be able to use both hands as well. In particular, the whistle system includes a fingergrip that allows the user to quickly move the whistle in position for use in a natural motion, while allowing the fingergrip to then quickly separate from the whistle to allow both hands of the user to be utilized. Alternatively, the whistle allows individuals with restricted movement in one arm to still officiate. A user having restricted movement in one arm can simply wear the whistle on one hand, move it into position in the mouth to be blown, and then quickly separated from the whistle to allow the signal to be indicated with one hand. The whistle system includes a whistle with a fingergrip. The fingergrip is securely attached to the whistle by a securement system that also allows the fingergrip to be separated from the whistle with an application of force. | 2012-06-14 |
20120148992 | Controller for Electrical Impulse Stress Exposure Training - A control module used in combination with an activation device for generating an activation signal in response to a stress exposure training event and an electrical impulse device for delivering an electrical shock to the user. The control module has a housing for being carried on the user. The module includes a controller function which sends a shock signal to the impulse device to shock the user according to prescribed shock criteria in response to an activation signal. The control module can be used with various activation devices including light-based force-on-force training or video shoot-back simulations. An operator input of the controller enables the prescribed shock criteria stored on the controller which is carried on the user to be adjusted by an operator directly at the module or remotely. | 2012-06-14 |
20120148993 | Practice model - A model for learning dentistry skills and including a shell attachable to a phantom head, through-holes disposed in the shell, teaching teeth individually arranged in the through-holes, and having a carrier plate attachable to the shell, such that a teaching tooth is releasably fixed on the shell and is adapted to be inserted into the model and removed therefrom at least one peg disposed on the carrier plate, and a holding chamber disposed in the peg, wherein a holding element projects from each tooth and passes through a through-hole in the shell and is aligned with a holding chamber and is inserted into the holding chamber, and a holding strip disposed between the shell and the carrier plate and adapted to contours of the carrier plate and the shell and disposed in openings, the holding strip being movable for securing the holding element of the teaching tooth to the carrier plate. | 2012-06-14 |
20120148994 | HUMAN BODY PARTIAL MANIKIN - A human body partial manikin having the same flexibility, elasticity, and texture as the human body is provided. And a manikin which has a feeling when it is cut open by means of a scalpel or scissors, similar to a feeling when an actual operation is performed by using a human body and is optimum for the anatomical practice of an inguinal hernia is provided. Accordingly, the human body partial manikin includes a skin portion which represents a skin layer on the surface of a lower abdomen of a human body, an abdominal external oblique muscle portion, an abdominal internal oblique muscle portion, a transverse abdominal muscle portion, a fascia transversalis portion, a fascia extraperitoneal portion, a peritoneum portion, and an abdominal cavity portion toward the inside of the manikin, wherein these respective portions are formed of a silicone resin. | 2012-06-14 |
20120148995 | APPARATUS AND RELATED METHODS FOR THE CONTROLLED ILLUMINATION OF A CONVEX SURFACE - Illumination provided to the interior of a convex surface can be controlled using a plurality of internal barriers separating light sources such as light emitting diodes. Such controlled illumination can simulate phases of the moon using logic which can be limited to yes or no Boolean decisions, thereby minimizing the complexity of required input. | 2012-06-14 |
20120148996 | METHOD FOR FACILITATING THE IDENTIFICATION OF SUITABLE OBJECT-WIPING MATERIAL AND DISPENSER THEREFOR - A method for facilitating the identification of suitable object-wiping material and dispenser ( | 2012-06-14 |
20120148997 | METHOD, SYSTEM, AND PROGRAM PRODUCT FOR CUSTOMIZING EDUCATIONAL MATERIALS - The invention provides a method, system, and program product for preparing customized educational materials. The invention may include, for example, receiving input from a user regarding the user's preferences for educational materials, retrieving core educational materials from a repository, accepting dynamic educational materials, and assembling the customized educational materials using the core educational materials, the dynamic educational materials, and the user's preferences. The invention may further include scheduling the delivery of the customized educational materials to a user. | 2012-06-14 |
20120148998 | COMPUTER GENERATED ENVIRONMENT FOR USER ASSESSMENT - One example embodiment includes a method for providing an assessment instrument, where the assessment instrument occurs within a computer generated environment. The method includes determining the assessment to be made and determining the types of responses to be elicited. The method also includes providing a computer generated environment designed to elicit the responses. | 2012-06-14 |
20120148999 | SYSTEMS AND METHODS FOR ANALYZING LEARNER'S ROLES AND PERFORMANCE AND FOR INTELLIGENTLY ADAPTING THE DELIVERY OF EDUCATION - A computer-aided educational system and method to further a student's understanding of a subject matter through analyzing data captured in an electronic learning system so as to determine correlation data corresponding to variables or trends which are determined to enhance, optimize, and/or improve one's learning abilities or understanding of educational content. The system and method generates reports based on the correlation data, develops statistical models that highlight learning and behavioral trends, and/or provides recommendations for adapting the learning system based on the correlation data and statistical models. | 2012-06-14 |
20120149000 | SYSTEMS AND METHODS FOR GUIDED INSTRUCTIONAL DESIGN IN ELECTRONIC LEARNING SYSTEMS - According to some embodiments, a system for providing guided instructional design. The system includes at least one processing device and at least one data storage device in communication with the at least one processing device. The at least one data storage device is configured to store information about at least one course. For each course, the at least one processing device is configured to present at least one predetermined course component to a first user, and for the at least one course component: present at least one course parameter, receive at least one first input from the first user in relation to the at least one course parameter, based on the at least one first input and at least one educational design element, present at least one modified course parameter to the first user; and receive at least one second input from the first user in relation to the at least one modified course parameter. | 2012-06-14 |
20120149001 | VERTICALLY INTEGRATED MOBILE EDUCATIONAL SYSTEM - A vertically integrated, mobile educational system for a child aged about 1 to about 12 years is presented comprising a mobile digital processing device that is optionally connected to a computer network and at least one mobile application provided to the mobile digital processing device. The one or more mobile applications include executable instructions that create a mobile interactive educational resource characterized by: providing a mobile extension of a web-based educational suite; integrating with the web-based educational suite according to an instructional plan designed to accomplish one or more specific educational objectives in a subject; and comprising one or more learning activities associated with a subject appropriate for the child. Additionally, the educational resource is substantially free of activities not teaching toward one or more educational objectives in a subject. | 2012-06-14 |
20120149002 | EDUCATIONAL KIT FOR DISPLAY DEVICE AND EDUCATIONAL METHOD UTILIZING THE SAME - An educational kit for a display device and an educational method utilizing the same is provided. The educational kit includes an upper housing, a lower housing, a display panel module and a circuit control panel. The display panel module is disposed between the upper housing and the lower housing. The circuit control panel is disposed between the display panel module and the lower housing. The method includes providing an educational kit for a display device; disassembling the display device into a plurality of components; and reassembling the components to form the display device. The educational method is accomplished by disassembling and reassembling the display device. | 2012-06-14 |
20120149003 | NERVE GRAFT - A nerve graft includes a lyophobic substrate, a carbon nanotube film structure, a protein layer, and a nerve network. The carbon nanotube film structure is located on a surface of the lyophobic substrate. The protein layer is located on a surface of the carbon nanotube film structure away from the lyophobic substrate. The nerve network is positioned on a surface of the protein layer away from the lyophobic substrate. | 2012-06-14 |
20120149004 | BLOOD COLLECTION DEVICES CONTAINING BLOOD STABILIZATION AGENT - Disclosed are devices for collecting and stabilizing blood that contain a blood stabilization agent which includes variegin or an analog thereof, a polysulfated disaccharide, or a combination thereof, each in an amount effective to stabilize blood. Methods of making and using the devices, and kits containing the devices, are also provided. | 2012-06-14 |
20120149005 | REACTION TREATMENT DEVICE AND REACTION TREATMENT METHOD - Disclosed herein is a reaction treatment device including a temperature control section which includes a first temperature control section disposed at an outer peripheral edge part of a group of reaction regions and a planar second temperature control section, wherein the first temperature control section and the second temperature control section are disposed opposite to each other, with the reaction region group therebetween. | 2012-06-14 |
20120149006 | CELLULOSE SUBSTRATES, COMPOSITIONS AND METHODS FOR STORAGE AND ANALYSIS OF BIOLOGICAL MATERIALS - The invention provides a method and article for storing genetic material or analytes from a biological sample by contacting said biological sample with a cellulose substrate comprising structural units of Formula I | 2012-06-14 |
20120149007 | METHOD FOR DETECTING ANALYTES - The invention provides an improved method for sensitive and specific detection of target molecules, cells, or viruses. The inventive method uses large area imaging to detect individual labeled targets complexed with a target-specific selection moiety. The invention eliminates wash steps through the use of target-specific selection through one or more liquid layers that can contain optical dye and density agents. By eliminating washes the invention simplifies instrumentation engineering and minimizes user steps and costs. The invention uses sensitive image analysis to enumerate individual targets in a large area, is scalable, and can be deployed in systems ranging in complexity from manual to highly automated. | 2012-06-14 |
20120149008 | CHROMATOGRAPHIC SYSTEM FOR NUCLEIC ACID DETECTION - The present disclosure provides a strip for separation and sequence specific detection of nucleic acids in a sample, a system for sequence specific detection of nucleic acids comprising the strip of the present disclosure and an epifluorescence detection device, and a method for qualitative and/or quantitative determination of a nucleic acid using the strip. The strip, system and method of the present disclosure is easy to use and provides accurate and reliable results due to its high sensitivity and specificity in a relatively short analysis time compared to the conventional assays. | 2012-06-14 |
20120149009 | VAPORIZATION DEVICE AND METHOD FOR IMAGING MASS SPECTROMETRY - Methods and apparatus for analyzing samples are disclosed. The samples are analyzed by vaporizing molecules from a sample in a sample area with a femtosecond laser beam under ambient conditions, ionizing the vaporized molecules with electrospray ionization under the ambient conditions to form ions; and analyzing and detecting the ions. | 2012-06-14 |
20120149010 | BACULOVIRUS-BASED PRODUCTION OF BIOPHARMACEUTICALS FREE OF CONTAMINATING BACULOVIRAL VIRIONS - The present invention relates to methods for the production of biopharmaceuticals implementing a baculovirus-based system. These methods advantageously allow the production of biopharmaceuticals with reduced or no contaminating baculoviral virions. | 2012-06-14 |
20120149011 | METHOD FOR DETECTING TARGET NUCLEIC ACIDS - The invention relates to a method for detecting target nucleic acids which are detected by means of a specific sequence tag which is not part of the target nucleic acid. | 2012-06-14 |
20120149012 | DNA Methylation Detection Methods - The present teachings provide DNA methylation quantification methods that avoid bisulfite treatment of DNA. Methylation-specific binding proteins (MeDNA binding proteins) and non-methylation specific binding proteins (non-MeDNA binding proteins) are employed in various embodiments to modulate the accessibility of nucleic acids to primer extension reactions. After selectively removing the target nucleic acids, the extension products can be analyzed and methylation quantitated. In some embodiments, the analysis comprises real-time PCR. | 2012-06-14 |
20120149013 | METHODS OF EVALUATING CELLS AND CELL CULTURES - Methods of evaluating the composition of a cell culture (e.g., to distinguish chondrocytes from fibroblasts) and methods for evaluating the phenotype of an individual cell (e.g., as a chondrocyte) are disclosed. The methods may be used, for example, for assessing chondrocyte cultures used for treatment of cartilage defects. In some embodiments, the invention involves identifying cell culture composition or the identity of a cell based on expression level of a fibroblast marker. In other embodiments, the invention involves comparing expression levels of at least one chondrocyte marker and at least one fibroblast marker in a cell culture sample or in an individual cell. In illustrative embodiments, the chondrocyte marker is hyaluronan and proteoglycan link protein 1 (HAPLN1), and the fibroblast marker is microfibrillar associated protein 5 (MFAP5). | 2012-06-14 |
20120149014 | METHODS FOR OBTAINING FETAL GENETIC MATERIAL - The present invention relates to a method of enriching fetal nuclei from a sample. Enriched fetal nuclei can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing. | 2012-06-14 |
20120149015 | Soybean Plant And Seed Corresponding To Transgenic Event MON87701 And Methods For Detection Thereof - The present invention provides a transgenic soybean event MON87701, and cells, seeds, and plants comprising DNA diagnostic for the soybean event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for said soybean event in a biological sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said soybean event in a biological sample, and methods for detecting the presence of said soybean event nucleotide sequences in a biological sample. The invention further provides methods of growing the seeds of such soybean event into soybean plants, and methods of breeding to produce soybean plants comprising DNA diagnostic for the soybean event. | 2012-06-14 |
20120149016 | Genetic Variants in the TCF7L2 Gene as Diagnostic Markers for Risk of Type 2 Diabetes Mellitus - Polymorphisms in the gene TCF7L2 are shown by association analysis to be a susceptibility gene for type II diabetes. Methods of diagnosis of susceptibility to diabetes, of decreased susceptibility to diabetes and protection against diabetes, are described, as are methods of treatment for type II diabetes. | 2012-06-14 |
20120149017 | DIAGNOSTIC MARKERS OF HUMAN FEMALE INFERTILITY - The subject invention pertains to methods and reagents for the diagnosis of female infertility, prognostic indicators for female infertility, compounds for the treatment of female infertility, compounds and methods for contraception. Methods and compounds are based on the levels of ebaf in endometrial tissue. Methods for diagnosing endometrial receptivity and bleeding function by screening a biological sample such as an endometrial tissue sample, or bodily fluid for the presence of ebaf. A contraceptive compound containing an effective amount of ebaf and a pharmaceutically acceptable carrier. A diagnostic kit for timing contraception containing reagents for screening a sample for the presence of ebaf. A method of treating endometrial irregularities by down-regulating the expression of ebaf. | 2012-06-14 |
20120149018 | Detection of Small Nucleic Acids - The present invention relates to compositions and methods for the detection and characterization of interfering RNAs such as micro RNAs (miRNAs) and small interfering RNAs (siRNAs) and other short nucleic acid molecules. More particularly, the present invention relates to improved methods for the detection and quantitation of interfering RNA expression. The present invention further provides for the detection of variants and types of miRNAs and siRNAs. | 2012-06-14 |
20120149019 | USE OF A BIS-MALEIC ANHYDRIDE CROSS-LINKING AGENT FOR FIXATION OF A CELL OR TISSUE SAMPLE - The present disclosure relates to novel bis-maleic anhydrides and to the surprising discovery that bis-maleic anhydride cross-linking agents can be used for preservation/fixation of a cell or tissue sample. Various bis-maleic anhydride cross-linking agent scan be used in methods requiring fixation of a cell or tissue sample. These reagents and methods are especially useful in procedures that require that the fixation agent be removed in order to facilitate analysis with other reagents. The inventive reagents and methods make it easier to reliably assay for various proteins, a nucleic acid and the like using analytical methods such as like immunohistochemistry, fluorescence in situ hybridization, RT-PCR, and the like. | 2012-06-14 |
20120149020 | THERMOCOOLER FOR THERMOCYCLING A SAMPLE - A sample processing apparatus includes a sample carrier receiving region configured to receive a sample carrier carrying at least one sample, at least one sample processing station that processes the at least one sample, and a thermal control system that controls thermocycling of the sample during processing of the sample by the at least one sample processing station, wherein the thermal control system includes a heating and/or cooling substrate with a thermocycling region, at least one guard heat region, and at least one thermal break between the thermocycling region and the at least one guard heat region. | 2012-06-14 |
20120149021 | Device for Filtration of Fluids Therethrough and Accompanying Method - A microfluidic device for separating target components from a source fluid includes one or more source channels connected to one or more collection channels by one or more transfer channels. The target components of the source fluid can be magnetic or bound to magnetic particles using a know binding agent. A source fluid containing magnetically bound target components can be pumped through the source channel of the microfluidic device. A magnetic field gradient can be applied to the source fluid in the source channel causing the magnetically bound target components to migrate through the transfer channel into the collection channel. The collection channel can include a collection fluid that is stagnant until a predefined volume of source fluid is processed or a predefined volume of target components accumulate in the collection channel, at which point collection fluid can be pumped into the collection channel to flush the target components out of the collection channel. The target components can be subsequently analyzed for detection and diagnosis. | 2012-06-14 |
20120149022 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND PROGNOSIS OF COLORECTAL CANCER - Certain embodiments of the present invention provide methods and compositions related to the detection of colorectal cancer based upon the identification of biomarkers and combinations of biomarkers that indicate the present of colorectal cancer. One embodiment of the present invention provides a method for detecting colorectal cancer in a subject by obtaining a biological sample from the subject; detecting one or more biomarkers present in the sample; and comparing the concentrations and/or expression levels of the one or more biomarkers within the biological sample with the concentrations and/or expression levels of the one or more biomarkers in a normal control sample. | 2012-06-14 |
20120149023 | ENGINEERED DEMETER 5-METHYLCYTOSINE DNA GLYOSYLASE WITH IMPROVED YIELD, STABILITY AND SOLUBILITY - Improved active DEMETER polypeptides with internal deletions are provided. | 2012-06-14 |
20120149024 | COTTON EVENT MON 88913 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF - The present invention provides a cotton plant event MON 88913 compositions and seed. Also provided are assays for detecting the presence of the cotton plant event MON 88913 based on a DNA sequence and the use of this DNA sequence as a molecular marker in a DNA detection method. | 2012-06-14 |
20120149025 | Screening Methods for Human Embryonic Stem Cells - This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described here, the role of feeder cells is replaced by components added to the culture environment that support rapid proliferation without differentiation. Effective features are a suitable support structure for the cells, and an effective medium that can be added fresh to the culture without being preconditioned by another cell type. Culturing human embryonic stem cells in fresh medium according to this invention causes the cells to expand surprisingly rapidly, while retaining the ability to differentiate into cells representing all three embryonic germ layers. This new culture system allows for bulk proliferation of pPS cells for commercial production of important products for use in drug screening and human therapy. | 2012-06-14 |
20120149026 | INSULIN RESISTANCE MARKER - It is provided an insulin resistance marker, a method of evaluating insulin resistance, a method of screening a substance that improves insulin resistance, and a pharmaceutical composition for improving insulin resistance. An insulin resistance marker including a polypeptide comprising at least any 15 continuous amino acids in the specific amino acid sequence (sequence of a proepithelin protein). An insulin resistance marker including a polynucleotide selected from the group consisting of a polynucleotide comprising at least any 45 continuous bases in the base sequence encoding the above specific amino acid sequence, and a polynucleotide that is complementary to the polynucleotide. | 2012-06-14 |
20120149027 | Method for Determining the Risk of Metastasis as an Indicator for Diagnostic Imaging - The present invention pertains to the field of in vitro diagnostics and relates to a method for determining the risk of metastasis of a tumor, wherein a high risk of metastasis shows that subsequent examinations by means of imaging methods are indicated for the patient. | 2012-06-14 |
20120149028 | DETECTION AND VISUALIZATION OF THE CELL CYCLE IN LIVING CELLS - The present invention relates to a nucleic acid molecule encoding a polypeptide specifically binding to proliferating cell nuclear antigen (PCNA), said nucleic acid molecule comprising a nucleic acid sequence encoding the amino acid sequence of SEQ ID NO: 2 or an amino acid sequence deviating from SEQ ID NO: 2 by conservative substitution of one or more amino acids in position 1 to 28, 38 to 52, 63 to 98 and 115 to 123 of SEQ ID NO: 2. The present invention also relates to a vector comprising the nucleic acid molecule of the invention, a host cell comprising the nucleic acid molecule of or the vector of the invention and a method of detecting the amount and/or location of PCNA in living cells, a method of screening for compounds having an effect on the cell cycle. | 2012-06-14 |
20120149029 | Magnetic Needle Biopsy - An apparatus and method for performing biopsies in-vivo using magnetically labeled nanoparticles is disclosed. One embodiment of the apparatus is called a magnetic needle. When used in a biopsy, one embodiment of the present invention collects diseased cells in-vivo which have been tagged with magnetic nanoparticles coated with receptors for specific diseased cells. | 2012-06-14 |
20120149030 | IMMUNOASSAY FOR THROMBIN DETECTION - The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody. | 2012-06-14 |
20120149031 | ANTI-CMET ANTIBODY AND ITS USE FOR THE DETECTION AND THE DIAGNOSIS OF CANCER - The present invention relates to the field of prognosis and/or diagnosis of a proliferative disease in a patient. More particularly, the invention relates to antibodies capable of binding to the human cMet receptor, as well as the amino acid and nucleic acid sequences coding for these antibodies. The invention likewise comprises the use of said antibodies, and corresponding processes, for detecting and diagnosing pathological hyperproliterative oncogenic disorders associated with expression of cMet. In certain embodiments, the disorders are oncogenic disorders associated with increased expression of cMet polypeptide relative to normal or any other pathology connected with the overexpression of cMet. The invention finally comprises products and/or compositions or kits comprising at least such antibodies for the prognosis or diagnostic of certain cancers. | 2012-06-14 |
20120149032 | ENZYME DETECTION DEVICE - An enzyme detection device ( | 2012-06-14 |
20120149033 | Antigen Binding Molecules that Bind EGFR, Vectors Encoding Same, and Uses Thereof - The present invention relates to antigen binding molecules (ABMs). In particular embodiments, the present invention relates to recombinant monoclonal antibodies, including chimeric, primatized or humanized antibodies specific for human EGFR. In addition, the present invention relates to nucleic acid molecules encoding such ABMs, and vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the ABMs of the invention, and to methods of using these ABMs in treatment of disease. In addition, the present invention relates to ABMs with modified glycosylation having improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function. | 2012-06-14 |
20120149034 | BIOMARKER FOR MENTAL DISORDERS INCLUDING COGNITIVE DISORDERS, AND METHOD USING SAID BIOMARKER TO DETECT MENTAL DISORDERS INCLUDING COGNITIVE DISORDERS - Methods are provided that detect cognitive impairment including mild cognitive impairment and Alzheimer disease by using a protein or its partial peptide that differs in presence or absence. Novel biomarkers are also provided for cognitive impairment and non-psychiatric disease, as well as methods for detecting cognitive impairment using such biomarkers. Specifically, a biomarker for diagnosis is provided that comprises a protein fragment or peptide of not less than 5 amino acid residues arising from at least one protein or peptide selected from the group of proteins consisting of an amino acid sequence expressed by SEQ ID NO: 1, 3, 6, 8, 10, 13, 15, 18, or 20 and selected from the group of partial peptide in these proteins consisting of an amino acid sequence expressed by SEQ ID NO: 2, 4, 5, 7, 9, 11, 12, 14, 16, 17, 19, or 21. | 2012-06-14 |
20120149035 | MODULAR POINT-OF-CARE DEVICES, SYSTEMS, AND USES THEREOF - The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications. | 2012-06-14 |
20120149036 | BIOASSAY METHOD FOR ANTIBODY AGAINST THYROID-STIMULATING HORMONE RECEPTOR, MEASUREMENT KIT FOR THE ANTIBODY, AND NOVEL GENETICALLY MODIFIED CELL FOR USE IN THE BIOASSAY METHOD OR THE MEASUREMENT KIT - The present invention provides a method and a kit for assaying a TSH receptor antibody, which are easy to manipulate and are safe. Specifically, the present invention provides a composition comprising a genetically modified cell forced to co-express a TSH receptor, a cyclic nucleotide responsive calcium channel, and a luminescent protein aequorin. Use of the composition enables the assay of a TSH receptor antibody contained in a sample. | 2012-06-14 |
20120149037 | COLORIMETRIC SENSORS CONSTRUCTED OF DIACETYLENE MATERIALS - Colorimetric sensors for detection of an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric detection of an analyte are also disclosed. | 2012-06-14 |
20120149038 | DIAGNOSIS OF AUTISM - A method for diagnosing autism in a subject is performed by determining the presence and concentration of specific peptides in the body fluid. The peptides have the amino acid sequences SKITHRIHWESASLL, SSKITHRIHWESASLL, and SSKITHRIHWESASLLR with the molecular masses 1779+/−1 Da, 1865+/−1 Da and 2022+/−1 Da, respectively. | 2012-06-14 |
20120149039 | DIAGNOSTIC APPARATUS FOR ORGANIC SAMPLE ANALYSIS - A diagnostic apparatus for organic-sample analyses including a fluid sucking and ejecting device to enable suction and inner storage or ejection to the outside of the fluid, a feeding needle that can be secured to the sucking device including an inner channel for passage of the fluids and to be inserted into containers for intaking or ejecting a given amount of the fluid, an actuating device, including a carriage, to spatially move the carriage along three axes, the carriage being susceptible of connection with the sucking and ejecting device, a first replacement station to house a plurality of feeding needles of the disposable type and suitable to enable automatic fastening and removal of one of the disposable feeding needles to and from the sucking device connected to the carriage, and a second replacement station to allow automatic fastening and removal of a precision feeding needle to and from the carriage. | 2012-06-14 |
20120149040 | Adam12, A Novel Marker For Abnormal Cell Function - The present invention provides a method, an assay and a kit for providing an indication of abnormal cell function. The present inventors describes ADAM12 as a overall general marker for abnormal cell function, and the present inventor for the first time demonstrate that ADAM12 is an important indicator of fetal chromosomal disease and placenta function. Specifically ADAM12 is a good marker for e.g. Downs's syndrome, trisomy 18, preeclampsia, Turner syndrome in both first and second trimester. The present inventors developed an enzyme-linked immunosorbent assay (ELISA) and a time-resolved immunofluorometric assay for the quantification of ADAM12 in serum. The present application demonstrates in several examples the variation of the ADAM12 level in fetal abnormality and/or adverse pregnancy outcomes correlated gestational age when compared to normal controls. It is an object of the invention to provide an improvement of the existing marker tests that exhibits a decreased false positive rate. | 2012-06-14 |
20120149041 | IDENTIFICATION AND QUANTIFICATION OF BIOMARKERS FOR EVALUATING THE RISK OF PRETERM BIRTH - Described herein are methods for evaluating the risk of preterm birth in pregnant subjects. The methods involve detecting and quantifying a first biomarker and a second biomarker associated with preterm birth in a biological sample from the subject. Also described herein are isolated biomarkers and kits useful in predicting the risk of preterm birth. | 2012-06-14 |
20120149042 | METHODS FOR PREDICTING OUTCOME IN TRAUMATIC BRAIN INJURY - The invention describes methods for predicting outcome for patients suffering from traumatic brain injury (TBI) by evaluating levels of markers commonly associated with cellular damage in bodily fluids. Utilization of such methods improves diagnosis and treatment of patients suffering from traumatic brain injury, thus potentially minimizing and/or eliminating long-term adverse effects in these patients. | 2012-06-14 |
20120149044 | INHIBITION OF MIGRATION INHIBITORY FACTOR IN THE TREATMENT OF DISEASES INVOLVING CYTOKINE-MEDIATED TOXICITY - The present invention relates to diagnostic methods for determining migration inhibitory factor (MIF) mRNA content in a sample, wherein MIF is human MIF polypeptide having a molecular weight of approximately 12.5 kDa and kits for detecting MIF. | 2012-06-14 |
20120149045 | LUMINESCENT LIVE AND DEAD CELL ASSAY - A method to detect live and dead cells in a sample with one bioluminogenic reagent is provided. | 2012-06-14 |
20120149046 | Bioluminescent Bacterial Detection - This invention relates to bioluminescent methods for detecting specific target bacteria, such as | 2012-06-14 |