21st week of 2013 patent applcation highlights part 57 |
Patent application number | Title | Published |
20130130888 | MULTIFUNCTIONAL CATALYST ADDITIVE COMPOSITION AND PROCESS OF PREPARATION THEREOF - The present invention relates to a multifunctional catalyst additive composition for reduction of carbon monoxide and nitrogen oxides in a fluid catalytic cracking process comprising an inorganic oxide; alumino silicate or a zeolite; a noble metal; a metal of Group I A; a metal of Group II A; a metal of Group III A; a metal of Group IV A; a metal of Group V A; a rare earth oxide; at least a metal of Group VIII. The composition is attrition resistant and is incorporated on a support. The present invention also discloses a process for preparing the multifunctional catalyst additive composition. The present invention also discloses a fluid cracking catalyst comprising the multifunctional catalyst additive composition. | 2013-05-23 |
20130130889 | PROCESS FOR MAXIMUM DISTILLATE PRODUCTION FROM FLUID CATALYTIC CRACKING UNITS (FCCU) - The present invention provides an improved fluidized catalytic cracking process coupled with a two stage regeneration process in which the activity of the circulating catalyst is independently controlled for cracking hydrocarbon feedstocks or the vapors at low severity to produce maximum light cycle oil/distillate in one riser whilst cracking recycle streams comprising heavy cycle oil (HCO), light cracked naphtha (LCN) etc. in a second riser operating at high severity to produce LPG. | 2013-05-23 |
20130130890 | CATALYST SLURRY PREPARATION SYSTEM AND USE THEREOF - The present invention relates to the use of a catalyst preparation system for the preparation of a diluted catalyst slurry. In particular, the invention relates to a catalyst preparation system comprising a mixing vessel for mixing a particulate catalyst and a liquid hydrocarbon diluent. According to the invention, diluted catalyst slurry is prepared in a mixing vessel comprising a rotatable axial impeller system comprising at least two double-bladed hubs. The invention also relates to a process for preparing diluted catalyst slurry for use in the preparation of a particulate polyethylene product in a loop reactor with the catalyst preparation system as described herein. | 2013-05-23 |
20130130891 | PRESSURE CONTROL OF THE CATALYST MIXING VESSEL - The present invention relates to a process for preparing catalyst slurry in a catalyst slurry preparation system and supplying catalyst slurry to an ethylene polymerization loop reactor wherein an accurate control of the pressure within said catalyst slurry preparation system is provided. More particularly, the present invention provides a method for preparing a catalyst slurry and supplying said catalyst slurry to an ethylene polymerization loop reactor, said catalyst slurry comprising solid catalyst and a liquid hydrocarbon diluent, wherein said method comprises the steps of:
| 2013-05-23 |
20130130892 | SULFOXIDATION CATALYSTS AND METHODS AND SYSTEMS OF USING SAME - Catalysts amenable to oxidizing sulfur compounds and systems and methods of using these catalysts to effect the removal of sulfur from crude oil and crude oil distillates are disclosed. The catalyst is disposed with a titanyl moiety which serves to selectively coordinate sulfur compounds and affect their oxidation. The titanyl may be bound within a polymer or on the surface of a polymer or on the surface or in the pores of an inorganic support. The resulting oxidized sulfur compounds are readily separated from the initial crude oil or crude oil distillate streams by traditional separation techniques arrayed as described in the systems and methods disclosed. | 2013-05-23 |
20130130893 | ACTIVATION OF DUAL CATALYST SYSTEMS - Methods are provided for liquid phase activation of dewaxing and/or hydrofinishing catalysts that include a molecular sieve or other acidic crystalline support. The methods are compatible with activating the catalysts as part of a catalyst system that also includes a hydrotreating catalyst. | 2013-05-23 |
20130130894 | Method Of Producing Catalytic Material For Fabricating Nanostructures - Methods of fabricating nano-catalysts are described. In some embodiments the nano-catalyst is formed from a powder-based substrate material and is some embodiments the nano-catalyst is formed from a solid-based substrate material. In some embodiments the substrate material may include metal, ceramic, or silicon or another metalloid. The nano-catalysts typically have metal nanoparticles disposed adjacent the surface of the substrate material. The methods typically include functionalizing the surface of the substrate material with a chelating agent, such as a chemical having dissociated carboxyl functional groups (—COO), that provides an enhanced affinity for metal ions. The functionalized substrate surface may then be exposed to a chemical solution that contains metal ions. The metal ions are then bound to the substrate material and may then be reduced, such as by a stream of gas that includes hydrogen, to form metal nanoparticles adjacent the surface of the substrate. | 2013-05-23 |
20130130895 | Superabsorbent Comprising Pyrogenic Aluminum Oxide - Superabsorbents comprising pyrogenic aluminum oxide exhibit a low caking tendency coupled with good absorption properties and rapid water absorption. | 2013-05-23 |
20130130896 | FOLIAR FERTILIZERS FOR CONTROLLING PESTS - Provided is an environmentally friendly and broadly applicable method for protecting plants or crop against pests and diseases by successive foliar sprays with aqueous liquids exhibiting high acidity or basicity. The sprays provide protection, and further supply the plant with phosphorus and potassium. | 2013-05-23 |
20130130897 | IMPROVING ACTIVITY OF CORN GLUTEN MEAL AS AN HERBICIDE USING DRY ACID TREATMENT - A composition comprises a substantially dry mixture of substantially dry corn gluten meal and substantially dry solid acid, wherein the amount of the substantially dry solid acid is effective to enhance the pre-emergence herbicidal activity of the substantially dry corn gluten meal. A method for selectively inhibiting the growth of undesirable plants comprises prior to the emergence of the undesirable plants, applying a substantially dry corn gluten meal and a substantially dry solid acid to a plot of soil so that the amount of the substantially dry solid acid applied to the plot of soil is effective to enhance the pre-emergence herbicidal activity of the substantially dry corn gluten meal, wherein the substantially dry corn gluten meal and the substantially dry solid acid are applied in an amount effective to inhibit the growth of the undesirable plants. | 2013-05-23 |
20130130898 | Fungicidal Compositions - The present invention relates to compositions of fungicidally active compounds comprising at least one active compound I selected from 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (3′,4′,5′-trifluoro-biphenyl-2-yl)-amide (fluxapyroxade), bixafen, fluopyram, isopyrazam, sedaxane, penflufen and penthiopyrad and at least one further active component II as defined below. The invention furthermore relates to a method for controlling harmful fungi, wherein the fungi, their habitat or the plant propagation material, the soil, the plants or the materials to be protected against fungal attack are treated with an effective amount of at least one active compound I in combination with at least one active component II or with an effective amount of a composition according to the invention, to a method for protection of plant propagation material, comprising contacting the plant propagation material with an effective amount of at least one active compound I in combination with at least one active component II or with an effective amount of a composition according to the invention, to a method for protecting plants after germination from the attack of foliar phytopathogenic fungi, which comprises treating the plant propagation material from which the plants are to grow with an effective amount of at least one active compound I in combination with at least one active component II or with an effective amount of a composition according to the invention, to the use of the composition according to the invention for controlling harmful fungi, and to plant propagation material comprising the composition. | 2013-05-23 |
20130130899 | HERBICIDAL COMPOSITIONS - A herbicide combination comprising of components (A) and (B) exhibit synergistic herbicidal effects, where
| 2013-05-23 |
20130130900 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING FLUROXYPYR AND PENOXSULAM, HALOSULFURON-METHYL, IMAZAMOX OR IMAZETHAPYR - An herbicidal synergistic composition containing (a) fluoroxypyr and (b) an ALS inhibitor herbicide, in which the ALS inhibitor herbicide is penoxsulam, halosulfuron-methyl, imazamox or imazethapyr, provides improved post-emergence weed control in rice, cereal and grain crops, pastures, rangelands, IVM and turf. | 2013-05-23 |
20130130901 | DEFOLIANT COMPOSITION AND METHOD - An aqueous suspension or slurry (suspension concentrate) contains a synergistic amount of thidiazuron, diuron and surfactants. The aqueous suspension contains surfactants in amounts to obtain a stable suspension or slurry without the use of organic solvents. | 2013-05-23 |
20130130902 | STABILIZED BIO-AVAILABLE SOLUBLE SILICATE SOLUTION - The present invention relates to dissolved silicate compositions in which the dissolved silicate is stabilized by at least two selected osmolytes and is therefore bioavailable. The composition and its dilutions are stable over a long period of time and are used in a wide field of applications for the benefit of living organisms such as plants, animals and humans. | 2013-05-23 |
20130130903 | Suppression of Foliar and Soilborne Pathogens - Disclosed herein is a method for increasing the production of crops, particularly wheat and soybean, using herbicide resistant cultivars. In one aspect of this method, the method increases crop yield by diminishing the impact of the root diseases caused by | 2013-05-23 |
20130130904 | METHODS TO PRODUCE POLYMER NANOPARTICLES AND FORMULATIONS OF ACTIVE INGREDIENTS - The present invention provides a composition including a polymer nanoparticle and at least one agricultural active compound incorporated with the nanoparticle, wherein the nanoparticle are less than 100 nm in diameter, and the polymer includes a polyelectrolyte. | 2013-05-23 |
20130130905 | Use Of A N-Vinyllactam / Vinylimidazol Copolymer As Dispersing Agent - The present invention relates to a use of a copolymer comprising N-vinyllactam, and vinylimidazol or a quaternized vinylimidazol in polymerized form as dispersing agent in an aqueous composition containing a water-insoluble pesticide. Further on, it relates to an aqueous composition which contains a copolymer comprising in polymerized form at least 20 mol % N-vinyllactam, and at least 1 mol % vinylimidazol or a quaternized vinylimidazol, a water-insoluble pesticide, and a dissolved salt. The invention also relates to a method for preparing the said composition by mixing water, the water-insoluble pesticide, the salt and the copolymer. Another subject is a method for controlling phytopathogenic fungi and/or undesired plant growth and/or undesired attack by insects or mites and/or for regulating the growth of plants, where said composition is allowed to act on the particular pests, their habitat or the plants to be protected from the particular pest, the soil and/or on undesired plants and/or the useful plants and/or their habitat. | 2013-05-23 |
20130130906 | SUBSTITUTED 6-(ALKYLBENZYLAMINO) PURINE DERIVATIVES FOR USE AS CYTOKININ RECEPTOR ANTAGONISTS AND PREPARATIONS CONTAINING THESE DERIVATIVES - 6-(alkylbenzylamino)purine derivatives of the general formula I for use as cytokinin receptor antagonists. R1 is selected from a group which includes, but is not limited to, hydroxyl, amino, nitro, thio and alkyl group. R2 denotes one to four alkyl groups. The invention also relates to preparations containing these derivatives and methods of using the derivatives. | 2013-05-23 |
20130130907 | PLANT PATHOGEN RESISTANCE - Azelaic acid or its derivatives or analogs induce a robust and a speedier defense response against pathogens in plants. Azelaic acid treatment alone does not induce many of the known defense-related genes but activates a plant's defense signaling upon pathogen exposure. | 2013-05-23 |
20130130908 | Agricultural Formulations with Acyl Morpholines and Polar Aprotic Co-Solvents - The present invention provides a formulation comprising a pesticide and/or a plant growth regulator; an acyl morpholine of the formula (I) where R is H, CH | 2013-05-23 |
20130130909 | DCMU RESISTANCE IN NANNOCHLOROPSIS - Provided herein are exemplary methods for controlling a density of algae growing in an aquatic environment. Some exemplary methods include applying an effective amount of 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU) to the density of algae growing in the aquatic environment, wherein the algae includes genus | 2013-05-23 |
20130130910 | SUSTAINED RELEASE MICROPARTICLES AND SUSTAINED RELEASE MICROPARTICLE-CONTAINING PREPARATIONS | 2013-05-23 |
20130130911 | POLYMER COMPOSITE MATERIAL WITH BIOCIDE FUNCTIONALITY - Polymer composite material with biocide functionality, preferably for the use in agriculture, comprising at least one base polymer compound and at least one biocide active ingredient, wherein the biocide active ingredient is an organic biocide that can be emitted from the polymer composite material by diffusion and/or osmosis and method of its production. | 2013-05-23 |
20130130912 | AGROCHEMICAL FORMULATION COMPOSITION - The invention relates to an agrochemical formulation composition. The agrochemical formulation composition comprising at least one agrochemical active component and a solvent, which solvent comprises one or more dialkyl carbonates of the formula CO(OR | 2013-05-23 |
20130130913 | Techniques for Protecting a superconducting (SC) Tape - Techniques for protecting a superconducting (SC) article are disclosed. The techniques may be realized as an apparatus for protecting a superconducting (SC) article. The apparatus may comprise a porous sleeve configured to fit around the superconducting (SC) article. The porous sleeve may be made of non-conductive, dielectric material. | 2013-05-23 |
20130130914 | HIGH-TEMPERATURE SUPERCONDUCTOR MAGNET SYSTEM - The invention relates to a high-temperature superconductor (HTS) magnet system, preferably for an insertion device for generation of high-intensity synchrotron radiation, consisting of the coil body ( | 2013-05-23 |
20130130915 | SUBSTRATE FOR SUPERCONDUCTING WIRE ROD, SUPERCONDUCTING WIRE ROD, AND METHOD FOR PRODUCING SUPERCONDUCTING WIRE ROD - The phase transition temperature, at which the crystal lattice of LMO that constitutes an oxide layer as an intermediate layer or as a part of an intermediate layer becomes cubic, is lowered. A substrate for a superconducting wire rod includes an oxide layer (LMO layer ( | 2013-05-23 |
20130130916 | SUPERCONDUCTING THIN FILM AND METHOD OF MANUFACTURING SUPERCONDUCTING THIN FILM - Adhesiveness between a metallic substrate and a metal oxide layer is made to increase. A superconducting thin film ( | 2013-05-23 |
20130130917 | METHOD FOR SPECIFIC ENRICHMENT OF NUCLEIC ACID SEQUENCES - The invention discloses a method for immobilizing nucleic acid probes to solid substrates. Also disclosed is a micro column format for specific sequence capture which enables efficient and convenient enrichment of target sequences from a complex source. The capture probes are immobilized onto microspheres or fibrous filter as the active component inside the column. The column format allows hybridization, post-hybridization wash and recovery of captured sequences all to take place in a simple device without sophisticated equipment. | 2013-05-23 |
20130130918 | EXERCISE GENOTYPING - The invention relates to a method for identifying a genetic predisposition of a subject to increased exercise endurance, increased muscular power, muscle damage and/or injury risk, a method for formulating an exercise program for improving physical performance, a kit suitable for use in the methods and use of the method for improving physical performance. | 2013-05-23 |
20130130919 | Long-Range Barcode Labeling-Sequencing - Methods for sequencing single large DNA molecules by clonal multiple displacement amplification using barcoded primers. Sequences are binned based on barcode sequences and sequenced using a microdroplet-based method for sequencing large polynucleotide templates to enable assembly of haplotype-resolved complex genomes and metagenomes. | 2013-05-23 |
20130130920 | HIGH THROUGH-PUT ANALYSIS OF TRANSGENE BORDERS - A method of analyzing, in chromosomal DNA having a transgene incorporated therein, a DNA flanking region derived from the chromosome which is adjacent to the transgene. Wherein, the DNA flanking region is characterized by isolation and digestion of genomic DNA with a restriction enzyme, ligation of a double stranded adapter to the isolated and digested genomic DNA, a primer extension reaction of the adapter ligated genomic DNA, and the isolation of the primer extension reaction product via a streptavidin-biotin interaction. The DNA flanking region is further characterized via subsequent PCR amplification reactions and DNA sequencing. | 2013-05-23 |
20130130921 | Kit, a Device and a Method for Detecting Copy Number of Fetal Chromosomes or Tumor Cell Chromosomes - The invention relates to a kit, a device and a method for detecting the copy number of fetal chromosomes and tumor cell chromosomes. The method for detecting the copy number of fetal chromosomes or tumor cell chromosomes of the invention includes the following steps: collecting maternal plasma or plasma of tumor patient; separating the plasma from blood cells in blood; preparing Deoxyribonucleic Acids (DNA) in the plasma into a sequencing library; sequencing the DNA sequencing library; comparing a sequencing result with a genomic sequence map to determine which chromosome the DNA sequence comes from and the length of each DNA sequence; and calculating the ratio of the DNA segments from the chromosomes to be detected to all DNA segments in the same sample by a sequencing and comparison result of DNA, correcting the ratio according to a GC content of the DNA segments from the chromosomes to be detected, and calculating the variation of the corrected ratio of the DNA segments from the chromosomes to be detected in a sample to be detected, and determining the copy number of the chromosomes to be detected according to degree of variation. | 2013-05-23 |
20130130922 | ANALYSIS OF METHYLATION SITES - A method for labeling unmethylated CpG dinucleotides within a DNA fragment, and use of the method in profiling of genomic DNA methylation. The present invention further provides modified DNA methyltransferase enzymes and compounds which are capable of being used by the enzymes as cofactors for use in the labeling method. | 2013-05-23 |
20130130923 | PROCESSES AND KITS FOR IDENTIFYING ANEUPLOIDY - Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood. | 2013-05-23 |
20130130924 | METHOD FOR ANALYZING D4Z4 TANDEM REPEAT ARRAYS OF NUCLEIC ACID AND KIT THEREFORE - The present invention relates to a method for analysing in vitro D4Z4 tandem repeat arrays of nucleic acid contained on nucleic acid representative of chromosomes, in particular on nucleic acid representative of Human chromosomes 4 and 10, and to a kit therefore. Said method is in particular suitable for determining the number of D4Z4 repeat units in said D4Z4 repeat arrays. Said method is based on stretching of nucleic acid and in particular on Molecular Combing and relies on the use of probes, especially nucleic acid probes, with a particular design. The invention also relates to a method for providing tools for the diagnosis of facioscapulohumeral muscular dystrophy (FSHD) and to a diagnostic kit therefore. The invention further relates to a method for identifying biochemical events and/or genetic in regions containing such tandem repeat arrays. | 2013-05-23 |
20130130925 | TOOL FOR DIAGNOSIS AND PROGNOSIS OF MATURE B-CELL NEOPLASMS - The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a plurality of genomic regions represented thereon, the genomic regions corresponding to regions wherein alterations, such as copy number alterations, at such locations correlate to specific, identifiable cancers, particularly mature B-cell neoplasms. The invention further provides methods of diagnosing and providing prognosis certain types of cancer, particularly mature B-cell neoplasms. The methods can comprise contacting a sample to a microarray according to the invention, allowing any genetic material in the sample to hybridize to the genomic regions on the microarray, analyzing the hybridizations, and correlating the hybridizations to certain cancer types, particularly mature B-cell neoplasms. | 2013-05-23 |
20130130926 | Methods for Screening Cells and Antibodies - The invention provides methods of detecting a change in cell growth patterns, methods of screening many different antibodies in one receptacle, and methods of detecting specific binding of an antibody to a protein or cell, wherein the antibody is in a mixture of many different antibodies. | 2013-05-23 |
20130130927 | DETECTION AND QUANTIFICATION OF MICRORNAS IN THE CIRCULATION AND THE USE OF CIRCULATING MICRORNAS AS BIOMARKERS FOR CANCER - The present invention relates to the identification of circulating miRNAs as biomarkers suitable for use in the diagnosis and prognosis of a number of cancers, in particular breast cancer. In addition, the invention relates to improved methods for the identification and quantification of such biomarkers in samples taken from patients. | 2013-05-23 |
20130130928 | METHODS FOR PREDICTING OR MONITORING WHETHER A PATIENT AFFECTED BY A CANCER IS RESPONSIVE TO A TREATMENT WITH A MOLECULE OF THE TAXOID FAMILY - The present invention concerns in vitro methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family based on a resistance expression signature, kits for performing the methods, and methods for screening or identifying a compound suitable for improving the treatment of a cancer with a molecule of the taxoid family or for reducing the resistance development during the treatment of a cancer with the molecule of the taxoid family. | 2013-05-23 |
20130130929 | METHODS, DEVICES, AND KITS FOR OBTAINING AND ANALYZING CELLS - A method for concentrating and isolating nucleated cells, such as maternal and fetal nucleated red blood cells (nRBCs), in a maternal whole blood sample. The invention also provides methods and apparatus for preparing to analyze and analyzing the sample for identification of fetal genetic material as part of prenatal genetic testing. The invention also pertains to methods and apparatus for discriminating fetal nucleated red blood cells from maternal nucleated red blood cells obtained from a blood sample taken from a pregnant woman. | 2013-05-23 |
20130130930 | METHODS AND DEVICES FOR OBTAINING AND ANALYZING CELLS - A method for concentrating and isolating nucleated cells, such as maternal and fetal nucleated red blood cells (nRBCs), in a maternal whole blood sample. The invention also provides methods and apparatus for preparing to analyze and analyzing the sample for identification of fetal genetic material as part of prenatal genetic testing. The invention also pertains to methods and apparatus for discriminating fetal nucleated red blood cells from maternal nucleated red blood cells obtained from a blood sample taken from a pregnant woman. | 2013-05-23 |
20130130931 | BIOMARKER FOR THE DIAGNOSIS, PROGNOSIS AND MONITORING OF CANCER - The present invention provides a new biomarker for the diagnosis, prognosis and monitoring of cancer, preferably breast and colon cancer, the PIK3R2 gene or any of its expression products; since high levels of PIK3R2 correlate with advanced tumor stages, and in the case of breast cancer, with invasive or metastatic capacity. Thus, the invention is also related to a method for the diagnosis, prognosis and monitoring of cancer, preferably breast or colon cancer, in which the quantification of said biomarker in a biological sample comprising tumor cells is necessary. | 2013-05-23 |
20130130932 | Method for Identifying Lineage-Related Antibodies - In certain embodiments, the method may comprise: a) obtaining the antibody sequences from a population of B cells; b) grouping the antibody sequences to provide a plurality of groups of lineage-related antibodies; c) testing a single antibody from each of the groups in a bioassay and, after the first antibody has been identified, d) testing further antibodies that are in the same group as the first antibody in a second bioassay. In another embodiment, the method may comprise: a) testing a plurality of antibodies obtained from a first portion of an antibody producing organ of an animal; b) obtaining the sequence of a first identified antibody; c) obtaining from a second portion of said antibody producing organ the sequences of further antibodies that are related by lineage to said first antibody; and, c) testing the further antibodies in a second bioassay. | 2013-05-23 |
20130130933 | BIOMARKER SIGNATURES FOR WELLNESS TESTING - This invention generally relates to the use of devices to measure and assess the level of biomarkers that are indicative of the general wellness of an individual and methods of correlating such information into a wellness index. | 2013-05-23 |
20130130934 | EFFICIENT HIGH-THROUGHPUT SCREEN FOR IDENTIFYING NOVEL CHEMICAL COMPOUNDS WHICH DISRUPT THE FUNGAL VACUOLE - A high-throughput screening method for identifying new anti-fungal compounds, including: growing an adenine-requiring mutant fungus under conditions to induce bioaccumulation of P-ribosylaminoimidazole; treating the mutant fungus with chemical compounds; and determining if the chemical compounds cause white discoloration of the mutant fungus. A method to determine the effective concentration of an anti-fungal. A method to detect chemical disruption of the fungal vacuole of a fungus. | 2013-05-23 |
20130130935 | High Fidelity Restriction Endonucleases - Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor. | 2013-05-23 |
20130130936 | Method of Conducting an Assay - The invention is directed to droplet actuator devices and assay methods. The invention includes assay methods of conducting an assay comprising combining a sample with an umbelliferyl derivative, wherein the sample potentially comprises an enzyme capable of cleaving the umbelliferyl derivative and where the umbelliferyl derivative comprises an umbelliferyl core modified with one or more modifying moieties. | 2013-05-23 |
20130130937 | SAMPLE HOLDER FOR MICROARRAY READER BASED ON EVANESCENT WAVE BIOSENSOR - A microarray reader ( | 2013-05-23 |
20130130938 | OLIGONUCLEOTIDE LIBRARY ENCODING RANDOMISED PEPTIDES - The invention relates to a method of producing an oligonucleotide library comprising a plurality of oligonucleotides, each oligonucleotide in the library having at least one predetermined position, a randomisation codon selected from a defined group of codons, the codons within said defined group coding for different amino acids. Vector, host cells containing such libraries and kits for the production of such libraries are also provided. | 2013-05-23 |
20130130939 | PORTABLE PHOTONIC SENSOR SYSTEM AS AN EARLY DETECTION TOOL FOR OVARIAN CANCER - A guided mode resonance (GMR) sensor that can be used to simultaneously detect an array of analytes. It provides a diagnostic system that can rapidly detect an array of biomarker proteins in patient samples (such as blood, serum or plasma for example) which can be used as an accurate means to conduct a differential analysis of proteins that allows the discrimination of early and late stages of disease, such as metastatic versus primary ovarian serous carcinomas. The GMR sensor can be provided in a compact size such that it can be portable. | 2013-05-23 |
20130130940 | MULTI-TARGETED PRIMING FOR GENOME-WIDE GENE EXPRESSION ASSAYS - The present invention is a method of generating a library of expressed cDNA sequences using multi-targeted primers that are complementary to degenerate motifs present in a large proportion of corresponding mRNA sequences. Multi-targeting priming (MTP) for genome-wide gene expression assays provides selective targeting of multiple sequences and counter-selection against undesirable sequences. Priming with MTPs in addition to oligo-dT can result in higher sensitivity, a greater number of genes whose expression is well measured, a greater number of genes whose differences in gene expression are detected to be statistically, and a greater power to detect meager differences in expression. | 2013-05-23 |
20130130941 | Lubricity Agents to Increase Pump Efficiency in Hydrate Inhibitor Applications - Saturated and unsaturated carboxylic fatty acids and alkylamine salts, alkyl esters and alkyl amide derivatives of these fatty acids are effective in improving the lubricity of hydrate inhibitor formulations, thereby effectively reducing the level of wear on moving parts of a pump under a load during pumping of the hydrate inhibitor formulation, for instance into an umbilical for a subsea hydrocarbon production operation. | 2013-05-23 |
20130130942 | Dissipative Surfactant Aqueous-Based Drilling System for Use in Hydrocarbon Recovery Operations from Heavy Oil and Tar Sands - A water-based drilling fluid which includes an aqueous fluid and a water-soluble dissipative surfactant composition is described, wherein the dissipative surfactant composition includes at least one fatty acid or ester derivative of a plant or vegetable oil. Also described are methods of using such aqueous-based drilling fluids including the dissipative surfactant composition as described in hydrocarbon recovery operations associated with oil/tar sand, where such fluids act to increase the dispersant qualities of hydrocarbons within the oil/tar sand, and where such fluid exhibit a reduced coefficient of friction. | 2013-05-23 |
20130130943 | MONO- AND POLYENOIC ACID AND METAL PARTICLE MIXTURES FOR BREAKING VES-GELLED FLUIDS - A method for breaking the viscosity of an aqueous fluid gelled with a viscoelastic surfactant (VES) includes: providing an aqueous fluid; adding to the aqueous fluid, in any order, components comprising: a VES comprising a non-ionic surfactant, cationic surfactant, amphoteric surfactant or zwitterionic surfactant, or a combination thereof, in an amount sufficient to form a gelled aqueous fluid comprising a plurality of elongated micelles, an unsaturated fatty acid comprising a monoenoic acid or a polyenoic acid; or a combination thereof; and a plurality of metallic particles to produce a mixture comprising dispersed metallic particles in the gelled aqueous fluid. The method also includes dissolving the metallic particles in the gelled aqueous fluid to provide a source of metal ions and heating the gelled aqueous fluid to a temperature sufficient to cause the unsaturated fatty acid to auto-oxidize to products present in an amount effective to reduce the viscosity. | 2013-05-23 |
20130130944 | Ultra High Viscosity Pill and Methods for Use with an Oil-Based Drilling System - A fluid pressure transmission pill (FPTP) having an ultra-high viscosity for use in association with hydrocarbon drilling and exploration operations, particularly, managed pressure drilling (MPD) operations, is described. The ultra-high viscosity pill is a weighted pill composition that includes a hydrocarbon fluid, a thixotropic viscosifying agent, one or more activators, an emulsifier/wetting agent, a fluid loss control additive, and a weighting material. In accordance with selected aspects of the described fluid pressure transmission pill, the ratio of the amount of the thixotropic viscosifying agent to the activator is a ratio of about 7:1, and the weighting material is a barium-containing solid-phase material. Also described are methods of use of such FPTP products in subterranean operations, such as well killing operations during managed pressure drilling. | 2013-05-23 |
20130130945 | Drilling Fluids Having Reduced Sag Potential and Related Methods - Invert emulsion drilling fluids that have extended emulsion stability and reduced sag potential can be realized through incorporation of colloidal particles therein. The invert emulsion drilling fluids can be free of organophilic clays. The organophilic clay-free drilling fluids can comprise: an oleaginous fluid continuous phase; an aqueous fluid internal phase; a surfactant; a weighting agent; and a plurality of colloidal particles, the colloidal particles comprising fibrous colloidal particles and at least one other type of colloidal particle; wherein at least a portion of the plurality of colloidal particles interact with the surfactant to form an associative supporting structure that inhibits sag of the weighting agent. | 2013-05-23 |
20130130946 | STABILIZATION OF EMULSIONS CONTAINING RESINOUS MATERIAL FOR USE IN THE FIELD OF OIL OR GAS WELL TREATMENTS - Emulsions for use in a well including: (a) a water-insoluble resinous material; (b) water; and (c) an emulsifier, wherein the emulsifier comprises a non-ionic, a cationic, or a zwitterionic emulsifier; wherein the continuous phase of the emulsion comprises the water; wherein a dispersed phase of the emulsion comprises the resinous material; wherein the dispersed phase is in the form of droplets having a size distribution range such that at least 50% of the droplets have a size of 0.5 micrometers-500 micrometers; wherein the resinous material of the droplets is in a concentration of at least 5% by weight of the water; and wherein the composition of the droplets has a viscosity of less than 2,000 Poise measured at 20° F. Methods include the steps of: (a) forming an emulsion described above; and (b) introducing the emulsion into a portion of a subterranean formation. | 2013-05-23 |
20130130947 | METHOD FOR IMPAIRING FLUID FLOW IN SUBTERRANEAN FORMATIONS - Loss of wellbore fluids (such as drilling fluids, completion fluids and workover fluids) into the flow passages of a subterranean formation may be reduced or eliminated by introducing into the wellbore in communication with the formation a composition containing a composite of a deformable core having a hardened coating which contains a viscosifying agent and, optionally, a crosslinking agent. The viscosity of the composition increases in-situ as the viscosifying agent, and optional crosslinking agent, disassociate from the deformable core and react. A fluid-impermeable barrier is thereby formed. The composites may also be used in spacers, well cements, workover and completion fluids as their need arises. | 2013-05-23 |
20130130948 | METALLIC PARTICLE ACTIVATED OXIDATIVE BREAKING METHOD AND SYSTEM - A method for breaking the viscosity of an aqueous fluid gelled with a water soluble polymer or a VES is disclosed. The method includes providing an aqueous fluid. The method also includes adding to the aqueous fluid, in any order: a water soluble polymer in an amount sufficient to form a gelled aqueous fluid having a viscosity, a water soluble oxidizing agent configured to generate free radicals and a plurality of metallic particles to produce a mixture comprising dispersed metallic particles dispersed within the gelled aqueous fluid, the metallic particles configured to dissolve in the gelled aqueous fluid and provide a reducing agent to accelerate the generation of free radicals. The method further includes dissolving the metallic particles in the gelled aqueous fluid to provide a source of at least one transition metal ion in an amount effective accelerate the generation of free radicals and reduce the viscosity. | 2013-05-23 |
20130130949 | WELLBORE SERVICING FLUID COMPRISING A CELLULOSE ETHER - A cellulose ether having (i) one or more substituents selected from the group consisting of methyl, hydroxyethyl and hydroxypropyl, (ii) one or more hydrophobic substituents, and (iii) one or more cationic, tertiary amino, or anionic substituents, and having a retained dynamic viscosity, % η | 2013-05-23 |
20130130950 | HYDROGEN BONDING MATERIAL FOR OILFIELD APPLICATION - Methods of treating a well, by providing a supramolecular polymer fluid comprising units connected via reversible hydrogen bonds to form a supramolecular polymer; by introducing the supramolecular polymer fluid in the well; and by treating the well with the supramolecular polymer fluid. | 2013-05-23 |
20130130951 | SU-8 NANO-COMPOSITES WITH IMPROVED TRIBOLOGICAL AND MECHANICAL PROPERTIES - Substantially homogenous compositions in accordance with the present disclosure can exist in various forms, such as bulk materials, coatings, films, laminates, inserts, or overlays, and include at least one polymer such as SU-8, at least one liquid lubricant, and optionally at least one nanomaterial that serves as an inorganic filler material. Such compositions exhibit enhanced tribological and mechanical properties compared to the at least one polymer in isolation, for instance, a 50% or greater coefficient of friction reduction, a 100% or greater wear life increase, a 10% or greater elastic modulus increase, and/or a 10% or greater hardness increase. The at least one nanomaterial can include a first nanomaterial providing increased hardness, and a second nanomaterial providing increased elastic modulus. Compositions in accordance with the present disclosure are suitable for biological and non-biological applications. | 2013-05-23 |
20130130952 | PROCESSES FOR PREPARING LOW VISCOSITY LUBRICATING OIL BASE STOCKS - A process for the oligomerization of C | 2013-05-23 |
20130130953 | WATER RESISTANT GREASE COMPOSITION - A grease with improved water resistance is based on a combination of a polyamide thixotrope with a water insoluble thickener, preferably a lithium soap/complex thickener and an antioxidant/corrosion inhibitor/antiwear additive package. The improvement is maintained when highly effective or aggressive rust inhibitors which normally tend to degrade water wash out resistance are present in the grease. Another advantage is that resistance to fretting is significantly improved to the extent that the greases containing these components are capable of achieving a high level of resistance to false brinelling. The greases are particularly useful for application in wind turbine bearings. | 2013-05-23 |
20130130954 | LUBRICANT OIL COMPOSITION - Provided is a lubricating oil composition, which is used in an internal combustion engine employing a fuel containing at least one kind selected from a hydrogenated product of natural fats and oils, a transesterification product of natural fats and oils, and a hydrogenated product of a transesterification product of natural fats and oils, which includes an alkali metal borate or a hydrate thereof in an alkali metal-corresponding amount of 10 to 1,000 ppm by mass in terms of total amount of the lubricating oil composition, and which can satisfactorily exhibit cleanness even in the case where the above-mentioned fuel is mixed therein or the case where ash content thereof is low. | 2013-05-23 |
20130130955 | LUBRICANT OIL COMPOSITIONS - Compositions comprise first antioxidants and first additives, such as, a surface additives, performance enhancing additives and lubricant protective additives and optionally second additives and/or second antioxidants. The compositions are useful to improve lubricants, lubricant oils and other lubricant materials. The compositions and methods generally provide longer shelf lives, increased oxidative resistance, improved quality and/or enhanced performance to lubricants or lubricant oils. | 2013-05-23 |
20130130956 | SYNERGISTIC MIXTURE - A synergistic mixture comprising from 1 to 99.9% by weight of compounds having structural elements (I) | 2013-05-23 |
20130130957 | GREASE COMPOSITION AND MECHANICAL PART - The invention provides a grease composition containing a base oil, a thickener and a rust inhibitor, characterized in that the rust inhibitor includes an organic sulfonate and a fatty acid amine salt. The grease composition of the invention exhibits excellent rust preventing characteristics and causes little damage to the environment. | 2013-05-23 |
20130130958 | HIGH MOLECULAR WEIGHT POLYMERS AS VISCOSITY MODIFIERS - A lubricating composition comprises a base oil and between | 2013-05-23 |
20130130959 | COSMETIC COMPOSITIONS CONTAINING ACRYLIC THICKENER - The invention relates to a composition, especially a cosmetic composition, comprising at least one acrylic thickener and at least one oil, as well as to methods of using such compositions. | 2013-05-23 |
20130130960 | TOILET SOAP WITH IMPROVED LATHER - The present invention relates to soap bars having improved lather. Specifically, by limiting amounts of myristic acid and keeping specifically defined ratios of sum of C | 2013-05-23 |
20130130961 | INHIBITING CORROSION AND SCALING OF SURFACES CONTACTED BY SULFUR-CONTAINING MATERIALS - A method of treatment for inhibiting sulfur-based corrosion or scaling or for removing scaling from a surface including inhibiting corrosion caused by sulfur-containing materials, reducing corrosion caused by sulfur-containing materials, inhibiting scaling caused by sulfur-containing and sulfur-containing materials in gas, liquid or solid phase or any combination of multiple phases of materials, reducing scaling caused by sulfur-containing and sulfur-containing materials, and removing scaling caused by sulfur-containing and sulfur-containing materials. The method involves contacting sulfur-containing materials with a composition containing a turpentine liquid. The method also involves contacting corrodible surfaces or surfaces prone to scaling with a composition containing a turpentine liquid. | 2013-05-23 |
20130130962 | ADHERING ACIDIC SANITARY CLEANER AND FRAGRANCER - The invention relates to a sanitary composition for cleaning and/or disinfecting and/or for fragrance release, which composition is applicable directly to the sanitary unit, adheres there and can be rinsed off only after a relatively large number of rinse operations, and which composition comprises surfactants and at least one adhesion promoter, said adhesion promoter being an oxo acid of the following formula | 2013-05-23 |
20130130963 | PACKAGING FOR A LIQUID DETERGENT COMPOSITION WITH ABRASIVE PARTICLES - A packaged product comprising a packaging in combination with a composition, said composition comprising at least one surfactant and abrasive particles to provide both cleaning of a surface and mild skin exfoliation benefits, wherein said composition consists of a liquid composition and said packaging comprises a textured surface to provide tactile cues to the delivery of the cleaning and exfoliating benefits of said composition. | 2013-05-23 |
20130130964 | SOLIDIFICATION MATRIX USING A CARBOXYMETHYL CARBOHYDRATE POLYMER BINDING AGENT - A cleaning composition includes a carboxymethyl carbohydrate polymer, sodium carbonate, and water. The carboxymethyl carbohydrate polymer, sodium carbonate, and water interact to form a hydrate solid. The solid cleaning composition exhibits little or no swelling even when heated to temperatures up to 120° C. | 2013-05-23 |
20130130965 | METHOD TO DETECT AND TREAT INFECTIOUS OR INFLAMMATORY DIARRHEA BASED ON REG1 - The present invention relates to methods for the diagnosis, treatment and prevention of infectious and/or inflammatory diarrhea. | 2013-05-23 |
20130130966 | METHOD OF DETERMINING THE METASTATIC POTENTIAL OF A TUMOR - The present invention relates to the field of tumor biology. It provides a method for determining the risk of metastasis of a tumor, in particular, the risk of hematogenous dissemination and/or homing/survival in bone marrow, wherein the expression of RAI2, and optionally of other genes, in a tumor sample obtained from the patient is determined. The invention further provides a kit for determining the expression of RAI2 and/or other genes. A pharmaceutical composition comprising RAI2 in gene or protein form is disclosed, in particular for preventing and/or treating metastasis of a tumor. | 2013-05-23 |
20130130967 | Method for Uses of Protein Precursors as Prodrugs - The present invention provides compositions useful as prodrugs and methods for making the same. The compositions include a fusion protein having a first delivery domain and a second protein precursor domain linked together via a linker sequence. The delivery domain is a protein capable of facilitating entry to a target cells via the endocytotic pathway, such as transferrin. The protein precursor is a prohormone or a profactor, such as proinsulin. Methods of this invention include the steps of selecting a protein suitable as the delivery domain, constructing a vector to encode the fusion protein, and expressing the fusion protein in a suitable expression host. Also disclosed is a method for targeted-delivery of prodrugs to livers and a method of reducing hepatic glucose production. | 2013-05-23 |
20130130968 | COMPOUNDS FOR ENZYME INHIBITION - Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases associated with the proteasome. The peptide-based compounds include an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation. Oral administration of these peptide-based proteasome inhibitors is possible due to their bioavailability profiles. | 2013-05-23 |
20130130969 | ANTIMICROBIAL PEPTIDE, BRANCHED FORMS THEREOF AND THEIR USE IN THE TREATMENT OF BACTERIA INFECTIONS - The instant invention refers to an antibacterial peptide with all aminoacids in D-configuration, possessing strong antimicrobial activity against Gram-negative and Gram-positive bacteria and | 2013-05-23 |
20130130970 | LACTADHERIN-DERIVED PEPTIDES AS ANTIVIRAL AGENTS - The present invention relates to monomeric and multimeric peptidic compounds which have antiviral activity, particularly against integrin-using viruses, more particularly against rotavirus. Further, the present invention refers to compositions comprising said peptidic compounds for medical use or for use as food additives. | 2013-05-23 |
20130130971 | Method for Inhibiting HIV Replication in Mammal and Human Cells - The present invention describes a method to inhibit replication of the human immunodeficiency virus (HIV) by negatively modulating or altering the cytoskeleton, more precisely the proteins forming the intermediate cytoskeletal filaments, wherein the said proteins are vimentin and/or keratin-10. The replication of the virus is inhibited in human cells by intervening in the structure of these proteins. The present invention is also related to the use of agents, which comprise peptides and/or interfering RNA and/or lipidic compounds, said agents producing a negative modulation or alteration of the cytoskeleton to prevent or to treat the HIV infection. The invention provides means and methods for altering the cytoskeleton/filament structure of cells, as a result of which the infection of human cells by HIV is disturbed and can even be completely inhibited. The cytoskeleton is altered by reducing the amount of vimentin and/or keratin (e.g. by transcriptional control using interfering RNA) or by using peptides that disrupt the cytoskeleton. | 2013-05-23 |
20130130972 | ARTIFICIAL SWEETNERS AND PERFORMANCE - The present invention relates to the field of nutritional compositions. In particular, the present invention relates to a nutritional composition comprising sugar substitutes and to their use, e.g., to increase exogenous carbohydrate oxidation, which has been shown to increase performance, for example the performance of athletes. | 2013-05-23 |
20130130973 | PEGYLATED C-PEPTIDE - The present invention relates to PEGylated C-peptide derivatives comprising at least one PEG group attached to the N-terminus, which exhibit improved pharmacokinetic and biological activity in vivo. | 2013-05-23 |
20130130974 | NOVEL SYNTHETIC APPROACH TO beta-AMINOBUTYRYL SUBSTITUTED COMPOUNDS - The present invention relates to process to prepare β-aminobutyryl compounds having β-amino acid core structural moieties and optionally having γ-phenyl and/or heterocyclic structural moieties. Such compounds are useful as key structure framework of modern drug chemistry. | 2013-05-23 |
20130130975 | Methods of Treating Glucose Metabolism Disorders - Methods of treating individuals with a glucose metabolism disorder, and compositions thereof, are provided. | 2013-05-23 |
20130130976 | METHODS OF TREATING AUTOIMMUNE DISEASES OF THE CENTRAL NERVOUS SYSTEM (CNS) AND NEURODEGENERATIVE DISEASES - An insulin degrading enzyme (IDE) inhibitor for use in the treatment of a disease selected from the group consisting of an autoimmune disease of the central nervous system and a neurodegenerative disease is disclosed. | 2013-05-23 |
20130130977 | POLYMER-BASED SUSTAINED RELEASE DEVICE - This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar. | 2013-05-23 |
20130130978 | METHOD OF TREATING ENDOTHELIAL DYSFUNCTION - Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders. | 2013-05-23 |
20130130979 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR - The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided. | 2013-05-23 |
20130130980 | Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors - The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors. | 2013-05-23 |
20130130981 | TREATMENT USING NEUBLASTIN POLYPEPTIDES - The invention relates to treatments of neuropathic pain, including tactile allodynia, and to treatments for reducing loss of pain sensitivity associated with neuropathy. The present treatments involve the use of neublastin (NBN) polypeptides. | 2013-05-23 |
20130130982 | NEUROPROTECTION BY HEPATIC CELLS AND HEPATOCYTE SECRETORY FACTORS - The present invention relates to compositions and methods for neuroprotection. In particular, provided herein are compositions (e.g., hepatocyte secretory factors) for alleviating and/or protecting against neuronal damage (e.g., resulting from stroke), and methods of use thereof. | 2013-05-23 |
20130130983 | FIBROBLAST GROWTH FACTOR MUTANTS HAVING IMPROVED FUNCTIONAL HALF-LIFE AND METHODS OF THEIR USE - Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino acid substitution of an alanine at a position corresponding to amino acid position 66 of human FGF-1 with a cysteine and/or a specific amino acid substitution of a phenylalanine at a position corresponding to amino acid position 132 of human FGF-1 with a tryptophan (based on the 140 amino acid numbering scheme of human FGF-1) are provided. Other amino acid mutations or substitutions may be combined. Polynucleotide sequences encoding the mutant FGF proteins and host cells containing such polynucleotide sequences are provided. Methods of administering a mutant FGF protein to an individual to treat an ischemic condition or disease or a wound or tissue injury are also provided. | 2013-05-23 |
20130130984 | Administration Of Heparin Binding Epidermal Growth Factor For The Protection Of Enteric Neurons - The invention provides for methods of protecting neurons within the enteric nervous system (ENS) comprising administering an EGF receptor agonist, such as heparin-binding EGF (HB-EGF). These methods include reducing damage of ENS neurons in patient s suffering from an intestinal injury. In addition, the invention provides for increasing intestinal motility in a patient suffering from an intestinal injury comprising administering HB-EGF. The invention also provides for methods of inducing neurite growth within the ENS in a patient suffering from intestinal injury comprising administering HB-EGF. | 2013-05-23 |
20130130985 | OXYTOCIN PEPTIDE ANALOGUES - Peptide analogues of oxytocin are described together with methods of treating conditions ameliorated by modulating oxytocin receptor. The peptide analogues are seleno or telluro peptide analogues. Methods of synthesis of selenocysteine, tellurocysteine and oxytocin analogues are also described. | 2013-05-23 |
20130130986 | CANCER TREATMENT WITH RECOMBINANT VECTOR - This disclosure provides modified cytosine deaminases(CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders. It further provides use of such modified CDs with a thymosin-alpha-1 polypeptide in the treatment of disease and disorders. | 2013-05-23 |
20130130987 | METHODS FOR INHIBITING IMMUNE COMPLEX FORMATION IN A SUBJECT - Polypeptides and other compounds that can bind specifically to the C | 2013-05-23 |