20th week of 2014 patent applcation highlights part 53 |
Patent application number | Title | Published |
20140135430 | UREA-MODIFIED BINDER FOR MINERAL FIBRES - An aqueous binder composition for mineral fibres comprises: (1) a water-soluble binder component obtainable by reacting at least one alkanolamine with at least one polycarboxylic acid or anhydride and, optionally, treating the reaction product with a base; (2) a sugar component; and (3) urea, the proportion of components (1), (2) and (3) being within the range of 10 to 80 wt. % of (1), 15 to 80 wt. % of (2), and 5 to 60 wt. % of (3), based on the solids content of components (1), (2) and (3) as measured after heat treatment for 1 hour at 200° C. | 2014-05-15 |
20140135431 | ASPHALT COMPOSITIONS WITH CRACKING RESISTANCE ADDITIVES - Methods are provided for upgrading the quality of an asphalt. The methods include mixing an asphalt feed with a cracking resistance additive that improves the low temperature properties of the asphalt while leaving the high temperature properties unchanged or minimally changed. The cracking resistance additive corresponds to a compound that is a liquid at both the low temperature performance grade for the asphalt and at mixing and/or storage temperature for the asphalt. Examples of compounds that, in an appropriate molecular weight range, are liquids across this broad temperature range include polyalphaolefins, alkylated naphthalenes, and organic esters. | 2014-05-15 |
20140135432 | OIL-BASED INK COMPOSITION - An oil-based ink composition comprising a colorant, an organic solvent and a polymeric compound, and optionally an alkylamine ethylene oxide derivative as a pH adjusting agent, in which the pH of an aqueous phase is from 5.5 to 10, when ions in the ink composition are transferred to water. This oil-based ink composition prevents corrosion of a nozzle plate and is improved in storage stability, and thus can ensure printer reliability such as ink-jet stability obtainable even after long storage thereof, and can withstand outdoor service environments. | 2014-05-15 |
20140135433 | TIRE WITH RUBBER CONTAINING FLAVONE - The invention relates to a pneumatic tire having a component containing a rubber composition comprising
| 2014-05-15 |
20140135434 | POLYESTER BINDER FOR FLOORING PRODUCTS - A flooring product is provided comprising at least one layer including a polymeric binder comprising at least one thermoplastic polyester resin, wherein the polyester resin comprises at least one renewable component. A flooring product is also provided that includes at least one layer comprising filler and at least one thermoplastic, high molecular weight polyester resin. The flooring product may also qualify for at least one point under the LEED System. A composition is also provided that can be melt mixed in low intensity mixers and processed into flooring layers. | 2014-05-15 |
20140135435 | Liquid Phosphite Compositions Having Different Alkyl Groups - A composition comprising a mixture of at least two different alkylaryl phosphites, wherein some alkyl groups have a different number of carbon atoms than other alkyl groups and wherein the mixture is a liquid at ambient conditions. | 2014-05-15 |
20140135436 | BLOCKED PREPOLYMERS AND ACRYLIC PLASTISOL COMPOSITIONS COMPRISING THE BLOCKED PREPOLYMERS - The invention generally relates to blocked prepolymers. More specifically, the invention generally relates to plastisol compositions comprising the blocked prepolymers. The blocked prepolymer is the reaction product of at least an isocyanate terminated prepolymer and a blocking agent, wherein the blocking agent is a nitrogen containing blocking agent. The isocyanate terminated prepolymer is the reaction product of at least one or more polyols comprising at least one polyol having an amine initiator and a stoichiometric excess of one or more organic polyisocyanate components. | 2014-05-15 |
20140135437 | TIRE WITH RUBBER TREAD CONTAINING COMBINATION OF RESIN AND VEGETABLE OIL, PARTICULARLY SOYBEAN OIL - This invention relates to a tire with a circumferential rubber tread composition comprised of a silica reinforced rubber composition containing diene based polymers in combination with traction resin(s) and vegetable oil, particularly soybean oil. | 2014-05-15 |
20140135438 | FLUORINATED COPOLYMER COMPOSITION - To provide a fluorinated copolymer composition from which a molded product excellent in the heat resistance and the stress crack resistance can be produced with good productivity. | 2014-05-15 |
20140135439 | POLYMER-ENCAPSULATED NON-PIGMENT PARTICLES - A non-pigment particle that includes a non-pigment inorganic particle having an average particle diameter of from 0.005 to 5 microns and an index of refraction of less than 1.8, a water-soluble sulfur acid-functional first polymer and a second polymer that at least partially encapsulates the non-pigment inorganic particle. | 2014-05-15 |
20140135440 | POLYPROPYLENE RESIN COMPOSITION FOR INTERIOR MATERIALS OF AUTOMOBILE WITH ADVANCED PAINT ADHESIVITY AND LOW SPECIFIC GRAVITY - Disclosed is a polypropylene resin composition for automobile interior trim parts with superior paint adhesivity and low specific gravity. More specifically, a polypropylene resin composition for automobile interior trim parts having superior paint adhesivity and low specific gravity is disclosed, wherein a base resin including polypropylene, a propylene-ethylene copolymer or a mixture thereof is mixed with a reinforcer including magnesium hydroxide and an ethylene-butene elastomer. The present polypropylene resin composition allows for direct painting of an automobile interior trim part surface without primer treatment and provides excellent resistance to damage caused by impact. | 2014-05-15 |
20140135441 | REINFORCED POLYAMIDE RESIN PELLET - (Problem to be Solved) | 2014-05-15 |
20140135442 | AQUEOUS BINDER COMPOSITIONS - The invention relates to mixtures of at least one acrylic resin dispersion A and a second dispersion B which is at least one of a polyurethane dispersion B1 which comprises, in its polymer, moieties derived from grafted fatty acids, and a mixture B2 of a polyurethane dispersion B21 and an aqueously dispersed alkyd resin B22, and to a method of use thereof for coating of porous substrates. | 2014-05-15 |
20140135443 | Thermoset Resin Composite Materials Comprising Inter-Laminar Toughening Particles - A resin system containing:
| 2014-05-15 |
20140135444 | TRANSPARENT FILMS - The invention relates to an optically transparent polymer film or extrudate product made of a polymer composition comprising a semi-crystalline polyamide having a melting temperature of at least 270° C. or a blend of the semi-crystalline polyamide (A) and a second polymer (B), and optionally at least one additive, wherein the semi-crystalline polyamide (A) is present in an amount of more than 50 wt. %, relative to the total weight of the polymer composition, the polymer composition in the optically transparent polymer film or extrudate product has a melting temperature (Tm-C) in the range of 270-340° C., and wherein the film or a part of the extrudate product has a haze of less than 12% and a light transmittance, of at least 88% measured with the method according to ASTM D1003A. | 2014-05-15 |
20140135445 | OLEFIN-BASED IONOMER RESIN COMPOSITION - The present application relates to an olefin-based ionomer resin composition, to an encapsulant, and to an optoelectronic device. The resin composition according to the present application may be used as an encapsulant for a variety of optoelectronic devices, and may exhibit superior adhesion to the substrates of the optoelectronic devices. In addition, according to the present application, an olefin-based ionomer resin composition, which can provide good workability and economic advantages in the manufacture of devices without negatively affecting components such as encapsulated optoelectronic elements or the wired electrodes of optoelectronic devices, may be provided. | 2014-05-15 |
20140135446 | METHODS FOR PREPARING POLYHETEROSILOXANES - This invention relates to methods for preparing polyheterosiloxane materials having at least two different non-Si metal elements. The polyheterosiloxane materials prepared by these methods are solid materials which can be easily dispersed in a solvent of choice. | 2014-05-15 |
20140135447 | PREPARATION OF IMIDE OLIGOMERS - Reactive extrusion can be used in a continuous, solvent-less preparation of imide oligomers involving two competing reactions among three ingredients, the first reaction between a dianhydride and a diamine and the second reaction between an endcap and the diamine. The imide oligomer can form a composite via conventional production methods or via formation of a film from imide oligomer re-melted in an extruder before being impregnated into tape or fabric. | 2014-05-15 |
20140135448 | OLIGO- AND POLYIMIDES - An oligo- or polyimide comprising one or two residue(s) of an anhydride based acetylenic end-capper, at least one EBPA residue, at least one residue of anaromatic di-amine, and optionally at least one residue of an aromatic non-acetylenic di-anhydride is disclosed. A method for obtaining such an oligo- or polyimide is also disclosed. | 2014-05-15 |
20140135449 | NOVEL POLYAMIDE, PROCESS FOR PREPARING SAME AND USES THEREOF - The present invention relates to a novel polyamide synthesized from biosourced monomers. The novel polyamide comprises the repeating unit of formula I below: | 2014-05-15 |
20140135450 | New coupling agents for elastomer compositions - In an elastomer composition, which preferably comprises an isoprene elastomer, use of an inorganic filler with a compound having the following formula (I), and which is optionally, in all or part, in a polymerized form: | 2014-05-15 |
20140135451 | Method for Providing a Side-Chain Dendrimer Vesicle - A method disclosed for making a side-chain dendrimer vesicle. The method includes the steps of: At first, there is provided a random copolymer with a narrow distribution of molecular weights by active polymerization and chemical modification. Then, chemical modification is executed to graft various generations of dendrimers to the random copolymer to provide a side-chain dendritic random copolymer with various generations. Two steps of emulsification are taken to induce macromolecular self-assembling of the side-chain dendritic random copolymer solution to form the macromolecular vesicle. The side-chain dendrimer includes C | 2014-05-15 |
20140135452 | VINYL ETHER END-FUNCTIONALIZED POLYOLEFINS - Provided herein are vinyl ether end-functionalized polyolefins and methods for producing the same. | 2014-05-15 |
20140135453 | METHOD FOR PREPARING A DIFUNCTIONAL POLY(GAP-co-THF)DIOL FOR PREPARATION OF POLYURETHANE HAVING EXCELLENT MECHANICAL PROPERTIES - Provided is a method for a poly(GAP-co-THF)diol prepolymer in which THF monomer units are copolymerized to GAP, having high difunctionality, a reduced amount of cyclic oligomer side products having a small molecular weight, a wide copolymer composition and controlled molecular weight. The resulted poly(GAP-co-THF)diol prepolymer according to the present invention is used as a binder for a high-energy PBX or composite propellant, specifically used as a binder in the preparation of polyurethane having excellent mechanical properties. | 2014-05-15 |
20140135454 | WATER-TRIGGERED SHAPE MEMORY OF PCL-PEG MULTIBLOCK TPUS - Water-triggered shape memory polymers based on poly(ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) multiblock hybrid thermoplastic polyurethanes. Urethane linkages were formed through the addition reaction between isocyanate groups of the lysine methyl-ester diisocyanate (LDI) and the hydroxyl groups of either (PEG) or PCL diol. | 2014-05-15 |
20140135455 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS - The present disclosure relates to the preparation of ketal compounds from polyols and oxocarboxylates, and uses thereof. | 2014-05-15 |
20140135456 | ARTICLES MADE FROM CROSSLINKED COPOLYMERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES - Disclosed are articles made from crosslinked copolymers comprising crosslinks between olefinically unsaturated positions in the backbone of one type of repeat unit and a second repeat unit that is a fluorovinylether functionalized aromatic repeat unit. The articles have enhanced surface fluorine that imparts improved soil, water, and oil resistance to the articles. | 2014-05-15 |
20140135457 | OXAZOLIDONE RING CONTAINING VINYL ESTER RESIN AND PRODUCTS THEREFROM - A process comprising contacting a) an epoxy resin; b) an adduct comprising at least one oxazolidone ring prepared from a multifunctional epoxy resin and an isocyanate compound; and c) an unsaturated acid to form a vinyl ester, is disclosed. | 2014-05-15 |
20140135458 | METHOD FOR THE PRODUCTION OF MDI DIMER - The invention relates to a method for the production of 4,4′-methylenebis(phenylisocyanate) dimer (MDI dimer) which is distinguished by an MDI dimer being obtained which is present in high purity. The MDI dimer which is produced according to the method according to the invention is distinguished by being essentially free of MDI and also urea derivatives. Furthermore, the invention relates to a corresponding MDI dimer and also the use thereof as crosslinker for polyurethanes. | 2014-05-15 |
20140135459 | HIGH PRESSURE LOW DENSITY POLYETHYLENE RESINS WITH IMPROVED OPTICAL PROPERTIES PRODUCED THROUGH USE OF HIGHLY ACTIVE CHAIN TRANSFER AGENTS - Disclosed is an ethylene-based polymer with a density from about 0.90 to about 0.94 in grams per cubic centimeter, with a molecular weight distribution (M | 2014-05-15 |
20140135460 | LOW BAND GAP COPOLYMER AND METHOD FOR MANUFACTURING SAME - Disclosed herein are a copolymer having a low band gap and a preparing method thereof, and more specifically, a copolymer having a low band gap and other various and excellent physical properties, and a preparing method thereof. | 2014-05-15 |
20140135461 | METHOD FOR PRODUCING OLEFIN POLYMER - A method for producing an olefin polymer including: polymerizing one or more α-olefins each having 6 to 20 carbon atoms in the presence of a metallocene catalyst to obtain an olefin polymer; deactivating and decalcifying the catalyst to obtain a decalcified polymerization reaction liquid; mixing the decalcified polymerization reaction liquid containing the olefin polymer with water; and washing the liquid with stirring at a stirring intensity of 0.1 kW/m | 2014-05-15 |
20140135462 | ETHYLENE-BASED POLYMERS AND PROCESSES TO MAKE THE SAME - The invention provides a process to form an ethylene-based polymer, said process comprising polymerizing ethylene in the presence of at least one free-radical agent, and in the presence of a “metal alkyl-containing compound” selected from the group consisting of the following: i) at least one “Group II metal alkyl-containing compound,” ii) at least one “Group III metal alkyl-containing compound,” or iii) a combination of i) and ii). The invention also provides a composition comprising at least one ethylene-based polymer, prepared from a free-radical polymerization, and wherein the ethylene-based polymer has the following property: y>0.28567x−0.00032, wherein y=vinyl/1000 C, as determined by 1H NMR, and x=mol % polymerized ?-olefin, as determined by 13C NMR. The invention also provides a composition comprising at least one ethylene-based polymer, prepared from a free-radical polymerization, and wherein the ethylene-based polymer has the following properties: A) a vinyl content greater than, or equal to, 0.3 vinyl per 1000 C (total carbons), and B) a polymerized alpha-olefin level less than, or equal to, 1.00 mole percent, based on the total moles of polymerized monomers. | 2014-05-15 |
20140135463 | MELT-FABRICABLE PERFLUOROPOLYMERS HAVING IMPROVED HEAT AGING PROPERTY - Heat aging of the composition comprising melt-fabricable tetrafluoroethylene/perfluoro(alkyl vinyl ether) copolymer, the alkyl containing 1 to 5 carbon atoms and melt flowable polytetrafluoroethylene is effective to cause thermal transformation of the composition in the solid state, which is epitaxial co-crystallization of the polymer components of the composition, and other valuable changes, such as increased continuous use temperature. | 2014-05-15 |
20140135464 | METHOD FOR THE PRODUCTION OF TERPOLYMERS BASED ON VDF, TRFE AND CFE, OR CTFE - A process for manufacturing terpolymers by polymerization of VDF (vinylidene difluoride), TrFE (trifluoroethylene), and CFE (1-chloro-1-fluoroethylene) or CTFE (chlorotrifluoroethylene) monomers in the presence of a radical polymerization initiator, characterized in that:
| 2014-05-15 |
20140135465 | METHOD FOR PRODUCING ETHYLENE-TETRAFLUOROETHYLENE COPOLYMER POWDER - Provided is a method for producing an ethylene-tetrafluoroethylene copolymer powder, whereby it is possible to simply and inexpensively produce an ethylene-tetrafluoroethylene copolymer powder excellent in handling efficiency from a slurry having an ethylene-tetrafluoroethylene copolymer dispersed in a fluorinated organic solvent. A method for producing an ethylene-tetrafluoroethylene copolymer powder, which comprises feeding, at a feeding linear velocity exceeding 0.10 m/sec., a slurry having ethylene-tetrafluoroethylene copolymer microparticles dispersed in a specific fluorinated organic solvent, to a centrifugal thin-film evaporator | 2014-05-15 |
20140135466 | Di-(tert-butyl cyclohexyl) peroxydicarbonate composition - Process for the preparation of a composition comprising di-(tert-butylcyclohexyl) peroxydicarbonate comprising the steps of (a) preparing a pre-mix comprising di-(tert-butylcyclohexyl) peroxydicarbonate, one or more organic solvents, a hydrophilic silica, and apolyalkoxylated butyl ether, and (b) milling the pre-mix resulting from step (a). | 2014-05-15 |
20140135467 | PROCESS FOR START-UP OF A POLYMERISATION REACTION FLUIDISED BED - Process for polymerization and, in particular, to a process for start-up of a gas phase fluidized bed polymerization reaction involving one or more monomers using a catalyst in a reactor. The process includes providing a start-up bed of particles in the reactor in the presence of the one or more monomers but in the absence of the catalyst, introducing at T | 2014-05-15 |
20140135468 | PROCESSES FOR THE PREPARATION OF RHEOLOGY MODIFIERS - Methods for preparing hydrophobically modified alkylene oxide urethane branched polymers. In an embodiment, the order of addition of reactants affects the properties of the resultant product urethane. In an embodiment, the time at which one or more reactants are added affects the properties of the resultant product urethane. | 2014-05-15 |
20140135469 | LIQUID CRYSTALLINE POLYMER COMPOSITION FOR FILMS - A film formed from a polymer composition containing one or more thermotropic liquid crystalline polymers is provided. The specific nature of the polymer or blend of polymers is selectively controlled so that the resulting polymer composition possesses both a low viscosity and high melt strength. The present inventor has discovered that this unique combination of thermal properties results in a composition that is both highly melt processible and stretchable, which allows the resulting film to be oriented to a degree greater than previously thought possible. | 2014-05-15 |
20140135470 | LIGNIN CONVERSION PROCESS - This specification discloses a complete method to manufacture polyester articles from freshly harvested ligno-cellulosic biomass. The process steps include pretreating the biomass and the converting the lignin to one of several possible organic steams by deoxygenating and dehydrogenating the lignin in the presence of a Raney Nickel catalyst, separating the organics, and then processing the organics into polyester feedstocks and converting those feedstocks to polyester. | 2014-05-15 |
20140135471 | PROCESSES FOR PRODUCING BUTANEDIOL (BDO), DIAMINOBUTANE (DAB), SUCCINIC DINITRILE (SDN) AND SUCCINAMIDE (DAM) - Processes that, make nitrogen-containing compounds include converting succinic acid (SA) or monoammonium succinate (MAS) derived from a diammoniurn succinate (DAS)- or MAS-containing fermentation broth to produce such compounds Including diammobmane (DAB), succinic dinitrile (SDN), succinic amino nitrile (SAN), succinamide (DAM), and related polymers. | 2014-05-15 |
20140135472 | AFFINITY TAGS ABLE TO DETECT FRAMESHIFTS - Described are polynucleotide sequences that encode peptide affinity tags with the surprising property that all of the possible out-of-frame peptide sequences are identical to each other, yet are distinct from the in-frame encoded peptide tag. The present invention includes peptide affinity tags incorporated in expressed proteins. Also described are ligands and antibodies that recognize the in-frame peptides and separate ligands or antibodies that recognize the out-of-frame peptides. | 2014-05-15 |
20140135473 | BIS-SULFHYDRYL MACROCYCLIZATION SYSTEMS - The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production. | 2014-05-15 |
20140135474 | UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins. | 2014-05-15 |
20140135475 | ANTIBODIES FOR BINDING TO NON-FUNCTIONAL P2X7 RECEPTORS IN TRIMERIC FORM - The invention relates to a novel epitope on P2X7 receptors, to antibodies for binding to the epitope and to peptides for generating the antibodies. | 2014-05-15 |
20140135476 | CHROMATOGRAPHY LIGAND COMPRISING DOMAIN C FROM STAPHYLOCOCCUS AUREUS PROTEIN A FOR ANTIBODY ISOLATION - The present invention relates to a chromatography ligand, which comprises Domain C from | 2014-05-15 |
20140135477 | MULTILIGAND CONSTRUCTS - Multiligand constructs and intermediate multivalent constructs for use in their preparation are described. The multiligand constructs have utility in diagnostic and therapeutic applications. | 2014-05-15 |
20140135478 | MATERIAL FOR SUPPORTED SYNTHESIS AND METHOD FOR GROWING OLIGONUCLEOTIDES OR PEPTIDES - The invention concerns a material composed of a porous support on which functionalized nanoparticles are grafted by covalent bonding, characterized in that at least part of the nanoparticles grafted by covalent bonding is housed inside surface pores of the support, and in that the support is silica-based and is in the form of porous particles of heterogeneous shape and size, the size of the particles being larger than 1 μm and preferably within the range of 5 to 200 μm. | 2014-05-15 |
20140135479 | POLYPEPTIDE ADJUVANT COMPOSITION WITH THERMOSTABILITY AND MANUFACTURE THEREOF - The present invention provides a polypeptide adjuvant composition with thermostability, which is designed from wild-type chicken interleikin-1β to construct a new chicken interleikin-1β, named CP-interleikin-1β. The CP-interleikin-1β having improved heat resistance keeps the original biological activity, and which helps to develop protein adjuvant with high efficiency and uses in medical application. The present invention also provides a method of manufacturing such polypeptide adjuvant composition. | 2014-05-15 |
20140135480 | Compositions and Methods for the Therapy and Diagnosis of Influenza - The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection. | 2014-05-15 |
20140135481 | HUMANIZED MONOCLONAL ANTIBODIES THAT PROTECT AGAINST SHIGA TOXIN INDUCED DISEASE - The present invention describes the preparation and use of biologically and immunologically active humanized monoclonal antibodies to Shiga toxin, a toxin associated with HC and the potentially life-threatening sequela HUS transmitted by strains of pathogenic bacteria. The present invention describes how these humanized antibodies may be used in the treatment or prevention of Shiga toxin induced diseases. One aspect of the invention is the humanized monoclonal antibody which binds Shiga toxin where the constant regions are IgG1-kappa and the variable regions are murine in origin. Yet another aspect of the invention is expression vectors and host cells transformed with such vectors which express the humanized monoclonal antibodies of the present invention. | 2014-05-15 |
20140135482 | Bispecific Anti ErbB3 / Anti cMet Antibodies - The present invention relates to bispecific antibodies against human ErbB-3 and against human c-Met, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof. | 2014-05-15 |
20140135483 | SOLUBLE INTEGRIN ALPHA-4 MUTANT - The present invention addresses the problem of providing a novel substance capable of interfering with various functions of integrin α4, and/or providing a novel substance capable of interfering with both integrin α4 and integrin α9. The present invention provides an integrin α4 mutant peptide having one portion of the extracellular domain of human integrin α4, and the like, and in concrete terms relates to a peptide and the like having the amino acid sequence of Sequence No. 4 through 9, and a pharmaceutical composition comprising as the active ingredient the same peptide. | 2014-05-15 |
20140135484 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 2014-05-15 |
20140135485 | 6-11 BICYCLIC KETOLIDE DERIVATIVES - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 2014-05-15 |
20140135486 | MULTI-ARM POLYETHYLENE GLYCOL DERIVATIVES, CONJUGATES AND GELS OF PHARMACEUTICALS AND THE SAME - A multi-arm polyethylene glycol (I) having different kinds of reactive groups and the uses thereof are disclosed, which is formed by polymerizing ethylene oxide with oligo-pentaerythritol as an initiator, wherein, PEG is same or different and is —(CH2CH2O)m—, the average value of m is an integer of 2-250; l is an integer of 1 or more. The method for producing the multi-arm polyethylene glycol having different kinds of reactive groups, the multi-arm polyethylene glycol active derivatives comprising linking groups X attached to PEG and terminal reactive groups F attached to X, the gels formed by the multi-arm polyethylene glycol active derivatives, the drug conjugates formed by the multi-arm polyethylene glycol active derivatives and drug molecules, and the uses thereof in preparing drugs are also disclosed. | 2014-05-15 |
20140135487 | IMMUNOSTIMULATORY G, U-CONTAINING OLIGORIBONUCLEOTIDES - Compositions and methods relating to immunostimulatory RNA oligomers are provided. The immunostimulatory RNA molecules are believed to represent natural ligands of one or more Toll-like receptors, including Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8). The compositions and methods are useful for stimulating immune activation. Methods useful for screening candidate immunostimulatory compounds are also provided. | 2014-05-15 |
20140135488 | BRACHYURY POLYPEPTIDES AND METHODS FOR USE - It is disclosed herein that Brachyury is expressed in human tumors, specifically in tumors of the small intestine, stomach, kidney, bladder, uterus, ovary, and testes, as well as in lung, colon and prostate carcinomas. Immunogenic Brachyury polypeptides are disclosed herein. These polypeptides can be used in diagnostic assays for Brachyury expression, as well as for inducing an immune response to Brachyury. Polynucleotides encoding the immunogenic Brachyury polypeptides, vectors including these polypeptides, host cells transformed with these vectors, and methods of using these polypeptides, polynucleotides, vectors, and host cells are provided. Methods of diagnosing a Brachyury-expressing cancer are also provided. Exemplary cancers include small lung, colon, intestine, stomach, kidney, bladder, uterus, ovary, and testes and prostate cancers. Methods of treating cancer are also disclosed. | 2014-05-15 |
20140135489 | DEVICE FOR PREPARING A SAMPLE - The invention provides a device for preparing a fluid sample, including but not limited to a sample comprising genomic DNA. | 2014-05-15 |
20140135490 | SYNTHESIS OF NUCLEOSIDES - A process for the preparation of nucleosides, derivatives and analogues thereof by coupling reaction of a protected suitable nitrogeneous purine or pyrimidine base, a derivative or analogue thereof and a protected suitable sugar in the presence of SnCl | 2014-05-15 |
20140135491 | EXTRACTION REACTOR AND ALSO METHOD FOR EXTRACTION FROM GRANULAR MATERIAL - The present disclosure relates to an extraction reactor with which granular material, in particular granular polyamide, can undergo extraction, soluble components being dissolved out of the granular material with an extraction liquid during the extraction. In the case of polyamide materials, these are for example oligomeric or monomeric components which have remained in the granular material during the polycondensation reaction for the production of the polyamide materials. | 2014-05-15 |
20140135492 | MODULATORS OF TOLL-LIKE RECEPTOR 7 - The present application includes a compound of Formula I or II: | 2014-05-15 |
20140135493 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS - Disclosed is a process for making diastereomeric compound of the formula (I): wherein m, n and R | 2014-05-15 |
20140135494 | Quinoxaline Compounds and Derivatives - The present invention provides oxazine compounds, method of using and method of making oxazine compounds and its pharmaceutical use. | 2014-05-15 |
20140135495 | STEREOSELECTIVE SYNTHESIS OF BICYCLIC HETEROCYCLES - The present invention relates to a process for the stereoselective preparation of compounds of formulae (1A) and (1B) | 2014-05-15 |
20140135496 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE - An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: | 2014-05-15 |
20140135497 | SYNTHESIS OF 2,4-DICHLORO-5-TRIFLUOROMETHYL-PYRIMIDINE - This invention relates to a novel method for the synthesis of 2,4-dichloro-5-trifluoromethyl-pyrimidine useful as intermediate in the manufacture of pharmaceutically active ingredients. | 2014-05-15 |
20140135498 | ORGANIC ELECTROLUMINESCENCE DEVICE - An organic electroluminescence device material comprising a metal complex having a neopentyl group, for example, as shown below; and an organic electroluminescence device comprising a substrate having thereon a pair of electrodes and at least one organic layer between the electrodes, the organic layer containing a light emitting layer, wherein any one of the organic layer contains the organic electroluminescence device material. | 2014-05-15 |
20140135499 | METHODS FOR THE TOTAL CHEMICAL SYNTHESIS OF ENANTIOMERICALLY-PURE 7-(2'-TRIMETHYLSILYL) ETHYL CAMPTOTHECIN - The present invention discloses and claims five (5) novel, highly efficient synthetic routes for the total synthesis of enantiomerically-pure (i.e., 99%) 7-(2′-trimethylsilyl)ethyl camptothecin (BNP1350; Karenitecin; Cositecan). These aforementioned synthetic schemes are the first to disclose the total syntheses of 7-(2′-trimethylsilyl)ethyl camptothecin using a highly novel direct, non-linear and convergent synthetic strategy which involves annealing the key C7-(trimethylsilyl)ethyl side chain-bearing A ring key synthons to an enantiomerically-pure tricyclic pyridone; rather than through the conventional methodology which incorporates the C7-(trimethylsilyl)ethyl side chain as the final synthetic step on a totally synthesized camptothecin parent compound. The current novel synthetic approaches reported herein since utilize desirably functionalized A-ring with preinstalled trimethyl silyl ethyl side chain, the aforementioned synthetic methodologies have a wider scope of making wide range of pharmaceutically relevant A-ring substituted BNP1350 analogs by substituting desirably functionalized nitro or protected amino phenyl carboxy A-ring as the starting material. | 2014-05-15 |
20140135500 | Process for the Preparation of Cycloheptapyridine CGRP Receptor Antagonists - The disclosure generally relates to a process for the preparation of compounds of formula I, including synthetic intermediates which are useful in the process. | 2014-05-15 |
20140135501 | MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME - Methods for producing moxifloxacin hydrochloride compounds having very low levels of impurities are provided. Compounds produced using such methods and pharmaceutical compositions including such compounds are also provided. | 2014-05-15 |
20140135502 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS - Processes for the preparation of charged crosslinkers bearing a sulfonic acid moiety are disclosed. These procedures also optionally include methods to convert the resulting products to substantially a single salt form. | 2014-05-15 |
20140135503 | NOVEL PROCESSES FOR THE PREPARATION OF PROSTAGLANDIN AMIDES - The subject of the invention is process for the preparation of the prostaglandin amides of the general formula I, where in the formula the bonds marked with dotted lines may be single or double bonds, in the case of double bounds at positions 5,6 and 13,14 they may be in cis or in trans orientation, Q stands for a hydroxyl-group and Z stands for a hydroxyl- or oxo-group, R | 2014-05-15 |
20140135504 | NOVEL POLYMORPHIC FORMS OF PERINDOPRIL (L)-ARGININE AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to novel and stable polymorphic forms of Perindopril (L)-Arginine designated as Form γ and amorphous form and processes for their preparation. The present invention also provides the novel polymorph Form γ with greater stability to heat and humidity and can be prepared on large scale by an efficient, economic and reproducible process. | 2014-05-15 |
20140135505 | 3-PHENYL-3-METHOXY-PYRROLIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION - The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention and to the use of these compounds for therapeutic applications. | 2014-05-15 |
20140135506 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS - Disclosed are methods for making chiral phosphorus ligands including chiral phosphines, chiral phosphine oxides, phosphonamides, and aminophosphines. The chiral phosphorus ligands prepared by the methods of the invention are useful as components of chiral catalysts, e.g., transition metal complexes. | 2014-05-15 |
20140135507 | TOTAL SYNTHESIS OF ARTEMISININ - The present invention provides a method for manufacturing artemisinin and its congeners from cyclohexenone as a starting material. | 2014-05-15 |
20140135508 | SPIRO EPOXIDES AS INTERMEDIATES - The present disclosure relates to compounds of formula I | 2014-05-15 |
20140135509 | Process for the Preparation of Benzyl [(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]d- ioxol]-4-yl]carbamate and Intermediates in the Process - The present invention is directed to a process for the preparation of benzyl [(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]carbamate (VI), | 2014-05-15 |
20140135510 | PROCESS FOR CONVERTING POLYSACCHARIDES IN AN INORGANIC MOLTEN SALT HYDRATE - A process is disclosed for converting a polysaccharide-containing biomass material to platform chemicals. | 2014-05-15 |
20140135511 | METHOD FOR PRODUCING HYDRIDE USING UNSATURATED COMPOUND HAVING CARBON NUMBER OF 4 AS RAW MATERIAL - The present invention relates to a method for producing a hydride having a carbon number of 4, comprising contacting, in liquid phase, an unsaturated compound having a carbon number of 4 as a raw material with a solid catalyst obtained by loading a metal element belonging to Groups 9 to 11 of the long periodic table on a support, thereby performing hydrogenation to produce a corresponding hydride having a carbon number of 4, wherein hydrogenation is performed in the presence of, as a solvent, a 1,4-butanediol having a nitrogen component concentration of 1 ppm by weight to 1 wt % in terms of nitrogen atom. | 2014-05-15 |
20140135512 | METHOD FOR PRODUCING GLYCIDOL - Disclosed is a method for producing glycidol by decarboxylation of glycerol carbonate. In the method, an ionic liquid catalyst is added for the reaction. According to the method glycidol can be produced in high yield and selectivity. The method enables the production of glycidol in an easy, simple and environmentally friendly way. | 2014-05-15 |
20140135513 | EO REACTOR, PROCESS AND THERMOCOUPLE PLACEMENT - Techniques are provided for determining the proper way to load thermocouple reactor tubes in multi-tubular ethylene oxide reactors containing a large number of reactor tubes containing silver catalysts. In these techniques, it is necessary to adjust the pressure drop so that oxygen conversion by thermocouple reactor tubes will closely match that of non-thermocouple reactor tubes. | 2014-05-15 |
20140135514 | GLYCIDYL ESTER REDUCTION IN OIL - Vegetable oils having a low level of glycidol esters are disclosed. Methods for reduction of the content of glycidol esters in edible oils are also disclosed | 2014-05-15 |
20140135515 | METHOD TO RECOVER FREE FATTY ACIDS FROM FATS AND OILS - Methods for recovering free fatty acids from fats and oils having high free fatty acid content are provided. In the method, fats and oils are treated with a mixture having an alcohol to result in a low-free fatty acid oily phase and an alcohol phase. The mixture may also include an alkali. The alcohol may be a monohydric alcohol and an aqueous alcohol, such as an aqueous alcohol having a concentration of at least about 15% alcohol by weight. The alcohol phase may be treated with an acid to form an aqueous alcohol phase and a lipid alcohol phase, wherein the lipid alcohol phase includes free fatty acids, which may be recovered. Fats and oils amenable to such a method may include, but are not limited to, waste fats, waste oils, high acid grease, high acid tallow, and corn oil, such as corn oil produced at an ethanol production plant. | 2014-05-15 |
20140135516 | Nanostructure having metal nanoparticles and method of assembly thereof - A nanostructure and method for assembly thereof are disclosed. An exemplary nanostructure includes a photocatalytic nanoparticle; a first tier of metal nanoparticles, each metal nanoparticle of the first tier being linked about the photocatalytic nanoparticle; and a second tier of metal nanoparticles, each metal nanoparticle of the second tier being linked to one of the metal nanoparticles of the first tier and located a distance from the photocatalytic nanoparticle greater than a distance between a metal nanoparticle of the first tier and the photocatalytic nanoparticle. | 2014-05-15 |
20140135517 | Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use - A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a platinum-ligand complex that can be prepared by reacting a platinum precursor and a ligand. | 2014-05-15 |
20140135518 | PERFLUOROPOLYVINYL MODIFIED ARYL INTERMEDIATES AND MONOMERS - A compound of formula (I) | 2014-05-15 |
20140135519 | CARBOXYLIC ACID ESTER PRODRUG INHIBITORS OF MEK - The invention generally relates to compounds having structure I: | 2014-05-15 |
20140135520 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER - A method that manufacturers an optically active carboxylic acid ester at high yield and high enantioselectivity is provided. An optically active carboxylic acid ester is manufactured at high yield and high enantioselectivity by reacting a racemic carboxylic acid and a specific alcohol or phenol derivatives in a polar solvent having a dipole moment of 3.0 or higher in the presence of an acid anhydride and an asymmetric catalyst, esterifying one enantiomer of the racemic carboxylic acid at high selectivity, and increasing the amount of esterified carboxylic acid by racemizing the optically active carboxylic acid which is the other enantiomer not used in esterification. | 2014-05-15 |
20140135521 | METHOD FOR PRODUCING ALPHA-HYDROXYCARBOXYLIC ACID ESTERS - The present invention relates to a continuous process for preparing alpha-hydroxycarboxylic esters by reacting at least one alpha-hydroxycarboxamide present in the liquid phase with an alcohol in the presence of a catalyst, which is characterized in that the resulting alpha-hydroxycarboxylic ester is at least partly separated from the reaction mixture via the gas phase. | 2014-05-15 |
20140135522 | BLENDED OIL COMPOSITIONS USEFUL AS DIELECTRIC FLUID COMPOSITIONS AND METHODS OF PREPARING SAME - In the present invention, compositions that are suitable for use as dielectric fluids are obtained from renewably sourced oils, and blends thereof. Renewably sourced synthetic esters as described herein are prepared using components obtained from natural or biologic feedstocks, wherein the feedstocks can be regenerated via conventional farming techniques. Dielectric fluids that can meet the industry standards are obtained using a process of combining appropriate percentages of components selected from synthetic polyol esters, natural oils, and mineral oil to customize the properties of the dielectric fluid obtained. Some of the properties that can be manipulated in the practice of the present invention include: electrical strength, resistivity, impulse strength, dissipation factor, permittivity, specific heat, thermal conductivity, chemical stability, gas absorption, pour point, viscosity, volatility, flash and fire point, and biodegradability. | 2014-05-15 |
20140135523 | CONTINUOUS PROCESS FOR PREPARING (METH)ACRYLATES OF C10-ALCOHOL MIXTURES - A continuous process for preparing (meth)acrylates of C | 2014-05-15 |
20140135524 | PERFLUOROPOLYVINYL MODIFIED ARYL INTERMEDIATES/MONOMERS - A compound of formula (I) | 2014-05-15 |
20140135525 | PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES - The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators. | 2014-05-15 |
20140135526 | COMPOSITIONS AND METHODS FOR 3-HYDROXYPROPIONATE BIO-PRODUCTION FROM BIOMASS - Methods of obtaining mutant nucleic acid sequences that demonstrate elevated oxaloacetate a-decarboxylase activity are provided. Compositions, such as genetically modified microorganisms that comprise such mutant nucleic acid sequences, are described, as are methods to obtain the same. | 2014-05-15 |
20140135527 | Process for Producing Acrylic Acids and Acrylates - In one embodiment, the invention is to a catalyst composition, comprising vanadium and titanium. Preferably, the molar ratio of vanadium to titanium in an active phase of the catalyst composition is greater than 0.5:1. | 2014-05-15 |
20140135528 | Chemical Installation - According to the present invention, a chemical installation is provided. The chemical installation comprises
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20140135529 | METHOD FOR ADMINISTERING AN NMDA RECEPTOR ANTAGONIST TO A SUBJECT - Compositions and methods for administering memantine to a subject are provided. In particular, a solid pharmaceutical composition in a unit dosage form for once daily oral administration is provided. The compositions comprises an extended release formulation of 22.5 mg to 33.75 mg memantine, or a pharmaceutically acceptable salt thereof, wherein administration of a dose of the composition to a human subject provides a mean plasma memantine concentration profile characterized by a change in memantine xconcentration as a function of time (dC/dT) that is less than 50% of the dC/dT provided by the same quantity of an immediate release form of memantine, determined in a time period between 0 hours to 6 hours after administration of memantine, and wherein dC/dT is measured in a single-dose human PK study. Methods of treating dementia, in particular Alzheimer's diseases, using the compositions are provided. | 2014-05-15 |