20th week of 2009 patent applcation highlights part 36 |
Patent application number | Title | Published |
20090123327 | METAL ALLOY FOR A STENT - A stent that is at least partially formed of a novel metal alloy, which novel metal alloy improves the physical properties of the stent. | 2009-05-14 |
20090123328 | WIRE FOR WELDING NICKEL BASED HEAT RESISTANT ALLOY - A wire for welding Ni-based heat resistant alloy, comprising: a composition containing, in mass %, Cr: 14.0 to 21.5%, Co: 6.5 to 14.5%, Mo: 6.5 to 10.0%, W: 1.5 to 3.5%, Al: 1.2 to 2.4%, Ti: 1.1 to 2.1%; Fe: 7.0% or less, B: 0.0001 to 0.020%, C: 0.03 to 0.15%, and a balance of Ni and unavoidable impurities, wherein a content of S and P contained in the unavoidable impurities is controlled to be, in mass %, S: 0.004% or less, and P: 0.010% or less, wherein the wire has a texture in which M | 2009-05-14 |
20090123329 | Metal Matrix Material Based On Shape-Memory Alloy Powders, Production Method Thereof and Use of Same - The invention relates to a metal matrix material based on shape-memory alloy powders, to the production method thereof and to the use of same. More specifically, the invention relates to a metal matrix material which is characterised in that it is based on particles of shape-memory alloy powder, having a base of copper at a concentration of between 45 vol.-% and 70 vol.-% in relation to the total volume of the material, said powder particles being supported by a metal matrix. The invention also relates to a method of producing the aforementioned material and to the use of same for absorbing vibrations, particularly acoustic and mechanical vibrations. | 2009-05-14 |
20090123330 | Method of sterilizing a package - A method of sterilizing packages in production of the packages, wherein the packages have an open end and a closed end. A gaseous sterilizing agent is used and kept in the gaseous phase throughout the sterilization process and an ambient temperature and a concentration of sterilizing agent in a sterilization zone where sterilization is performed are measured and used for controlling the amount of sterilizing agent introduced in the sterilization zone. | 2009-05-14 |
20090123331 | UV STERILIZATION OF USER INTERFACE FOMITES - Techniques for sterilizing a fomite are disclosed. A UV sterilization apparatus includes a housing for enveloping a fomite inside the housing. The housing is composed of a material that prevents transmission of electromagnetic radiation in the ultraviolet range. Attached to the housing is a closure element, and the closure element is also composed of a material that prevents transmission of electromagnetic radiation in the UV range but allows transmission of electromagnetic RADIATION in the visual range. An ultraviolet light source is attached to an internal surface of the housing or an internal surface of the closure element, and the light source sterilizes the fomite enclosed inside the housing by transmitting ultraviolet electromagnetic radiation towards the fomite. | 2009-05-14 |
20090123332 | STERILIZATION POUCH WITH INTERNAL AND EXTERNAL INDICATORS - A sterilizable pouch having both internal and external sterilization record indicators to indicate whether attempted steam sterilization of the pouch and contents was successful or unsuccessful. The pouch preferably has one indicium in each indicator responsive to multi-parameter sterilization by steam, and another indicium in each indicator responsive to gas sterilization, such as using ethylene oxide. | 2009-05-14 |
20090123333 | Maintaining Disinfection of Medical Equipment - A method is provided for maintaining the disinfection of medical equipment, in particular medical endoscopes ( | 2009-05-14 |
20090123334 | Device and Method for Monitoring the Temperature to Which a Product has Been Exposed - A device for monitoring the temperature to which a product has been exposed, comprising at least one spatially structured element, constituted by a material indicating a preset level of temperature and a preset exposure time interval, and adapted to be applied to a monitored product. The indicator material is selected among materials which detectably change their morphological and/or structural and/or chemical and/or physical state once the material is placed in a condition in which it can absorb a preset amount of heat. | 2009-05-14 |
20090123335 | Sensor Chip and Sensor System - It is intended to provide a sensor chip that enables detection of a deterioration state of a reagent applied on a reaction portion when measuring a concentration of a measurement object substance and a sensor system that enables a correct measurement by using the sensor chip for detecting the reagent deterioration state. A sensor chip including two substrates opposed to each other, a spacer layer sandwiched between the substrates, a multiple reaction portions provided in the spacer layer, and detection electrode units disposed on surfaces of the substrates facing to the spacer layer and exposed to the reaction portions, wherein an identical reagent A is applied on two or more of the reaction portions, and another reagent B that reacts with the reagent A is applied on at least one of the two reaction portions and a sensor system including the sensor chip and a measurement unit for comparing current values from the two or more reaction portions on which the identical reagent A is applied. | 2009-05-14 |
20090123336 | MICROFLUIDIC CHIPS FOR RAPID MULTIPLEX ELISA - A microfluidic chip comprises a substrate and a channel or multiple channels in the substrate. Each channel includes a tortuous path section or multiple tortuous path sections. A receptor for the detection of an analyte can be immobilized in a tortuous path section, for example by adsorption. Different receptors can be immobilized in different tortuous path sections of each channel or in different channels for simultaneous detection of multiple analytes. The chip is especially useful for running immunoassays, particularly ELISA. | 2009-05-14 |
20090123337 | Cartridge - A cartridge A to be mounted to a separate apparatus is provided. The cartridge includes a liquid introduction port | 2009-05-14 |
20090123338 | BUBBLE-RESISTANT INJECTOR PORT FOR FLUIDIC DEVICES - An bubble-resistant injector port for fluidic and microfluidic devices includes an air-exhaustion feature to reduce the inclusion of bubbles or voids in injected samples, particularly in samples injected by a micropipette. The air-exhaustion feature comprises an air-exhaustion cavity in gas communication with the injector port through a narrowed channel that permits a flow of air into the cavity, while impeding a flow of injected liquid into the cavity. | 2009-05-14 |
20090123339 | Bio-Waste Sterilizer - Bio-waste sterilizers are described. In one implementation an exemplary system has waste transport vessels that can be intermittently heated and pressurized, for example, with steam, and are interconnected to provide multiple sterilization pathways for waste as the waste is transported. Selected sterilization pathways may depend on attributes of the waste. Sterilization factors, such as mechanical shredding, application of steam, application of pressure, maintenance of temperature, separation of liquid, etc., are integrated into the waste transport features of the system, which can be made compact to save space while processing relatively large bulk amounts of materials, such as medical wastes. The system maintains safe isolation of bio-hazardous components in the waste from the external environment. A system controller provides parameters management, smart sterilization cycle control, quality assurance, safety management, diagnostics, and reporting over a network. | 2009-05-14 |
20090123340 | WATER QUALITY MONITORING DEVICE AND METHOD - A monitor device is attached to the water supply line of a consumer where it repeatedly measures a characteristic that correlates to quality of water in the water line. Each of a succession of a water quality values is derived from one or more of the measurements. The process continues at selected intervals to continuously monitor the condition of water in the line. Each new value can be compared to a reference value representing a maximum acceptable level of contaminants. If the water quality value exceeds the reference value, an overvalue signal is produced, indicating an unacceptable level of contaminants in the water. Additionally, the values can be transmitted to a central collection facility where they are correlated with values transmitted by similar devices on the supply lines of other consumers to track the quality of water of a supply system over time. | 2009-05-14 |
20090123341 | STEAM STERILIZING SYSTEM - A steam steriliser is described wherein the means of generation of the vacuum is a vacuum pump functioning in conditions of saturated or almost saturated steam at high temperatures, without a cooling system, and comprising a circuit of lubrication with a tank, wherein a lubricant fluid circulates, resistant to high temperatures and with high anti-emulsifying power, with means of filtration able to separate the steam from the lubricator fluid. | 2009-05-14 |
20090123342 | Fuels for Hydrogen Generating Cartridges - The present invention increases the amount of hydrogen produced or released from reactions between a metal hydride fuel and liquid reactant. The present invention also decreases the volume of a hydrogen generating cartridge by reducing the pH of the liquid reactant. | 2009-05-14 |
20090123343 | AIR HANDLER AND PURIFIER - A system that captures and eliminates indoor pollutants and chemical and biological agents within a HVAC system by breaking down the pollutants and chemical and biological threats into non-hazardous molecules. The surface area created by crystalline titanium dioxide nano-structures results in highly effective elimination rates when catalytic ionization by UV exposure occurs. The catalyst is activated with UVA light. | 2009-05-14 |
20090123344 | Framed freshener - A framed freshener provides a thermal formed cavity, or thermoplastic shell, carrying scented gel that fits into a picture frame. The present invention locates a fragrant gel in a thermal formed cavity or thermoplastic shell or container which is then placed within a suitably designed picture frame. Coupling a fragrance with a photo in a frame, the present invention seeks to foster memories in those who view the frame. Additionally, the shell carrying gel makes the frame a decorative air freshening device. The picture frame and the opening for the fragrance container can be die cut to any shape. An alternate embodiment has the shell supported in a wire frame upon a base. | 2009-05-14 |
20090123345 | AROMA LAMP - The aroma lamp contains a base member having a circuit member and a Universal Serial Bus (USB) connector. A fan module is positioned facing upward on a top surface of the base member. A hollow support member covers the top surface of the base member and the fan module. The support member has a vertical tube with surrounding openings which penetrates an aroma producing element and a light generating element is positioned at a top end of the vertical tube. A hollow lamp shade is detachably joined to the support member and houses the aroma producing element and the light generating element inside. When the USB connector is connected to a computer, the fan module is turned on and drives air to flow upward against the aroma producing element. The aroma producing element vaporizes and the aroma is spread outside the lamp shade. | 2009-05-14 |
20090123346 | Modular Fluidised Bed Reactor - The fluidised bed reactor according to the invention comprises a reaction chamber ( | 2009-05-14 |
20090123347 | FLUID TREATMENT SYSTEM - There is disclosed a water treatment appliance, particularly for on-the-counter treatment of potable water. The appliance comprises: a base unit comprising a pump, a housing and a cooling unit for chilling water in the housing; a removable water reservoir engageable with the housing; a control panel comprising a water dispensing switch; an outlet for dispensing treated water from the fluid treatment system; and a treatment cartridge removably disposed in the housing. The treatment cartridge comprises a first chamber and a second chamber in communication with one another. The first chamber is in communication with the housing and has disposed therein a filter element. The second chamber is in communication with the outlet and has disposed therein an ultraviolet radiation lamp. | 2009-05-14 |
20090123348 | Steam Reforming - An apparatus for steam reforming of hydrocarbons comprises a heat exchange reformer having disposed within a plurality of vertical catalyst-filled tubes, through which a gas mixture comprising hydrocarbon and steam may be passed, and to which heat may be transferred by means of a heat exchange medium flowing around the external tube surfaces, wherein heat exchange adapting means are provided within the reformer so that the tubes have a zone of lower heat exchange extending from the bottom of the catalyst up to 25% of the catalyst depth with no heat exchange enhancement means provided in that zone. A process for steam reforming of hydrocarbons employs this apparatus. | 2009-05-14 |
20090123349 | Self-propagating combustion cyclone reactor - A self-propagating combustion cyclone reactor includes a reaction chamber delimited by a circumferential wall in which at least one reductant inlet and a plurality of oxidizer inlets are formed in a tangential manner. Reductant and oxidizer are fed, together with inert gas, through the inlets into the chamber in a cyclonic manner to induce self-propagating combustion reaction to generate a product of high purity metal, such as titanium, zirconium, hafnium, or silicon, semiconductor substance. The reactor serves as a continuous reactor for generation of metal or semiconductor substances of high purity. | 2009-05-14 |
20090123350 | Recovery of precious metals and their compounds from natural quartz ore using sodium silicate manufacturing techniques - This patent is an improvement of the well known process outlined in U.S. Pat. No. 4,336,235. The current invention is unique in the fact that it applies this well-known manufacturing technique to the recovery of precious metals locked in natural quartz complexes. The desired products of the process described herein are the precious metals and their compounds, which are not recoverable in appreciable yields by standard mining recovery techniques from the natural quartz ore complexes. In the aforementioned patent the application as a viable mining recovery operation is not obvious, nor is the invention presented herein covered in the claims of the aforementioned patent. By applying the process described in the original patent to precious metals bearing quartz ore complexes, greater yields of precious metals than are currently attainable can result from the mining recovery operations | 2009-05-14 |
20090123351 | PROCESS FOR THE PREPARATION OF CALCIUM PHOSPHATE GRANULES OF THE HYDROXYAPATITE TYPE - The objective of the present innovation is a new process for the preparation of calcium phosphate granules of the hydroxyapatite type. The preparation process of a business for the said granules based on the invention is a hydrolysis process of a brushite dicalcium phosphate, in a basic milieu which is characterised by the fact that an aqueous suspension of brushite dicalcium phosphate is treated with lime, in the presence of an effective quantity of a carboxylic acid. | 2009-05-14 |
20090123352 | Pollution control in wood products dryer operation - Problems associated with deposition of contaminants from air streams in transport ducts in the wood products industry and other sources of such contaminants are at least minimized by close coupling a cyclone separator/scrubber to the source of the air stream. | 2009-05-14 |
20090123353 | SOLVOTHERMAL METHOD FOR PREPARING VANADIA-TITANIA CATALYST HAVING NANO STRUCTURE FOR DECOMPOSING CHLORINATED ORGANIC COMPOUNDS - The present invention relates to a method for preparing a vanadia-titania catalyst having a core-shell structure, which is highly active in decomposing chlorinated organic compounds such as dioxin present in the exhaust of an incinerator. | 2009-05-14 |
20090123354 | Selective Oxidation Agent of Hydrocarbons to Synthesis Gas Based on Separate Particles of O-Carrier and Hydrocarbon Activator - A solid material is presented for the partial oxidation of natural gas. The solid material includes a solid oxygen carrying agent and a hydrocarbon activation agent. The material precludes the need for gaseous oxygen for the partial oxidation and provides better control over the reaction. | 2009-05-14 |
20090123355 | PROCESS FOR PREPARING OF NANOWIRES OF METAL OXIDES WITH DOPANTS IN LOWER VALENCE STATE - The present invention provides a process for the preparation of nanowires of metal oxides with dopant elements in lower valence state. The nanomaterials/materials with dopants in lower valence state are important as these exhibit markedly different characteristics than higher valence state materials of same composition. Nanowires show markedly enhanced properties in lateral direction. The invented process presents a procedure for preparation of different types of nanowires in oxide form that are useful for different applications. In this a precursor is ignited in a specially designed container/enclosure that produces the product with the described features. The process is simple and involves a single step/stage is of very short time per batch. The invention provides a process, which gives controlled size of nanowires and is suitable for the production of nanowires/nanomaterials of desired metal oxides with dopant elements in valence state. | 2009-05-14 |
20090123356 | Inorganic hydrogen compounds - Provided is a semiconductor doped with an increased binding energy hydrogen species and a method of making the doped semiconductor. | 2009-05-14 |
20090123357 | METHOD FOR MAKING SILICA NANOPARTICLES BY FLAME SPRAY PYROLYSIS ADOPTING TWO-FLUID NOZZLE - The invention relates to a method for making silica nanoparticles using a flame reactor, which includes a droplet spray having a two-fluid nozzle and a burner of a quintuple tube structure. In this method, droplets of silicon alkoxide as liquid Si compound are sprayed through the droplet spray of the flame reactor. A flame is generated by the flow of inert gas, oxygen, hydrogen and air simultaneously into the burner of the flame reactor. The liquid Si compound is delivered through the flame of the burner to produce silica nanoparticles having a mean particle size ranging from 9 nm to 68 nm. Resultant nanoparticles are collected and recovered in a particle collector. The droplets sprayed under high pressure from a silicon alkoxide solution are directly oxidized in the flame, thereby producing spherical silica nanoparticles. | 2009-05-14 |
20090123358 | Process for the Production of Monoliths by Means of the Sol-Gel Process - Process for the production of monoliths by means of the sol-gel process, comprising the following steps:
| 2009-05-14 |
20090123359 | Reaction apparatus for producing trichlorosilane and method for producing trichlorosilane - A reaction apparatus for producing trichlorosilane in which metal silicon powder M is reacted with hydrogen chloride gas, thus generating trichlorosilane, includes: an apparatus body into which the metal silicon powder is supplied; and an ejection port for ejecting the hydrogen chloride gas into the apparatus body from the bottom part of the apparatus body, wherein a plurality of holed pieces having a through hole penetrating in the thickness direction and a plurality of pellets interposed between these holed pieces are stacked in a mixed state on the upper side of the ejection port. | 2009-05-14 |
20090123360 | Inorganic hydrogen compounds - Compounds are provided comprising at least one neutral, positive, or negative hydrogen species having a binding energy greater than its corresponding ordinary hydrogen species, or greater than any hydrogen species for which the corresponding ordinary hydrogen species is unstable or is not observed. Compounds comprise at least one increased binding energy hydrogen species and at least one other atom, molecule, or ion other than an increased binding energy hydrogen species. One group of such compounds contains one or more increased binding energy hydrogen species selected from the group consisting of H | 2009-05-14 |
20090123361 | High Density Storage of Ammonia - A solid ammonia storage and delivery material comprising an ammonia absorbing/desorbing solid material, said storage and delivery material having been compacted to a density above 50% of the theoretic skeleton density provides a solid ammonia storage material which is easy to produce and handle and has a very high density of stored ammonia which is readily released under controlled conditions even though the porosity of the material is very low, and which storage material is safe for storage and transport of ammonia without special safety measures. | 2009-05-14 |
20090123362 | Process for producing nanocrystalline alpha-AI2O3 - A process is claimed for producing nanocrystalline α-Al | 2009-05-14 |
20090123363 | METHOD FOR PRODUCING AN ALPHA-ALUMINA POWDER - The present invention provides a method for producing an α-alumina powder. The method for producing an α-alumina powder comprises steps of:
| 2009-05-14 |
20090123364 | Process for Hydrogen Production - A process is described for the production of hydrogen from a hydrogen-containing compound within a reactor comprising a first and a second zone separated by a selective hydrogen-permeable membrane, in which a hydrogen-producing reaction occurs in the first zone and hydrogen permeates from the first zone to the second zone through the selective hydrogen-permeable membrane, in which a sweep gas stream is combined with permeated hydrogen in the second zone, wherein the partial pressure in the second zone of the reactor is maintained at a level of greater than 30 psi (207 kPa). | 2009-05-14 |
20090123365 | Multifunctional nanostructures, methods of synthesizing thereof, and methods of use thereof - A nanostructure and methods of synthesizing same. In one embodiment, the nanostructure includes a nanospecies, a hydrophobic protection structure including at least one compound selected from a capping ligand, an amphiphilic copolymer, and combinations thereof, wherein the hydrophobic protection structure encapsulates the nanospecies, and at least one histidine-tagged peptide or protein conjugated to the hydrophobic protection structure, wherein the at least one histidine-tagged peptide or protein has at least one binding site. | 2009-05-14 |
20090123366 | Targeted Therapy - In order to target a diseased material in a subject, a monocyte, or monocyte-derived cell, such as a macrophage, which incorporates a magnetic material, such as a magnetic particle or a ferrofluid, preferably having a biocompatible coating, is proposed to be administered. A magnetic energy source may then be applied to the subject to destroy, rupture or inactivate the diseased material. Alternatively, the monocyte or monocyte derived cell may additionally include a therapeutic agent, which is thereby targeted at the diseased material. | 2009-05-14 |
20090123367 | Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases - The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active sHASEGP domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. Included are modified amino-terminal leader peptides that enhance secretion of sHASEGP. The invention further comprises sialated and pegylated forms of a recombinant sHASEGP to enhance stability and serum pharmacokinetics over naturally occurring slaughterhouse enzymes. Further described are suitable formulations of a substantially purified recombinant sHASEGP glycoprotein derived from a eukaryotic cell that generate the proper glycosylation required for its optimal activity. | 2009-05-14 |
20090123368 | USE OF DKK-1 PROTEIN IN THE CANCER DIAGNOSIS - Use of DKK-1 protein or the nucleic acid sequence in preparation of cancer diagnostic agents or kits, method to detect liver cancer with the monoclonal antibody thereof, the kit comprising anti-DKK-1 antibody or protein specific nucleic acid probes, together with a label, and method to detecting specific DKK-1 protein expression are disclosed. | 2009-05-14 |
20090123369 | Styrylpyridine Derivatives and Their Use for Binding and Imaging Amyloid Plaques - This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits. | 2009-05-14 |
20090123370 | ALPHAVBETA6 PEPTIDE LIGANDS AND THEIR USES - AVβ6 peptide ligands, functional variants thereof and their nucleic acids encoding them are disclosed with their uses in the treatment and imaging of AVβ6 mediated diseases. | 2009-05-14 |
20090123371 | MOLECULAR SIGNATURE OF CANCER - The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme. | 2009-05-14 |
20090123372 | DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY - The present application discloses methods for identifying inhibitors with high binding-affinity for the carbonic anhydrase-IX (CA-IX) enzyme using click chemistry and uses the candidates thereof as positron emission tomography (PET) imaging agents. | 2009-05-14 |
20090123373 | AMYLOID-IMAGING AGENTS - A molecular probe for use in the detection of amyloid in a subject includes a dibenzothiazole derivative. | 2009-05-14 |
20090123374 | METHODS FOR DETERMINING CANCER RESISTANCE TO HISTONE DEACETYLASE INHIBITORS - Described herein are methods and compositions for determining whether a particular cancer is resistant to or susceptible to a histone deacetylase inhibitor or to histone deacetylase inhibitors. The methods include analysis of the expression levels of at least four biomarker genes associated with response to a histone deacetylase inhibitor. Also described herein are methods and compositions for increasing the likelihood of a therapeutically effective treatment in a patient, comprising an analysis of the expression levels of at least four biomarker genes associated with response to a histone deacetylase inhibitor. Also described herein are isolated populations of nucleic acids derived from a cancer sensitive to or resistant to a histone deacetylase inhibitor. Further described are kits and indications that are optionally used in conjunction with the aforementioned methods and compositions. | 2009-05-14 |
20090123375 | CCR3 Inhibition for Ocular Angiogenesis and Macular Degeneration - Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of inhibitors of the CCR3 receptor or its ligands eotaxin (CCL11), eotaxin-2 (CCL24) or eotaxin-3 (CCL26) inhibits ocular angiogenesis. | 2009-05-14 |
20090123376 | THERAPEUTIC AGENTS WITH DECREASED TOXICITY - The present invention relates to therapeutic agents with reduced toxicity comprising a serum albumin binding peptide (SABP), a targeting agent and a cytotoxic agent. The present invention also relates to methods for reducing the toxicity of therapeutic agents and methods of treatment using the therapeutic agents with reduced toxicity. | 2009-05-14 |
20090123377 | Method for Testing Substances or Mixtures of Substances,Use of Said Method and Corresponding Test Kits - The invention relates to a method for testing substances and mixtures of substances for toxic characteristics, to the use of said method and to corresponding test kits. The method is essentially based on the determination of a fatty acid binding protein from the liver, L-FABP. The use of said method provides an early indication of carcinogenic and tumour-promoting characteristics of the tested substance or mixture of substances. | 2009-05-14 |
20090123378 | Uses and compositions for treatment of ankylosing spondylitis - The invention provides methods, uses and compositions for the treatment of ankylosing spondylitis (AS). The invention describes methods and uses for treating ankylosing spondylitis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to reduce signs and symptoms of ankylosing spondylitis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of ankylosing spondylitis in a subject. | 2009-05-14 |
20090123379 | NOVEL SCREENS TO IDENTIFY AGENTS THAT MODULATE RETINAL BLOOD VESSEL FUNCTION AND PERICYTE FUNCTION AND DIAGNOSTIC AND THERAPEUTIC APPLICATION THEREFOR - The present invention provides methods for determining or identifying compounds that modulate the function of an isolated retinal pericyte or blood vessel, wherein a change in the contractile state of said pericyte or blood vessel is determined in the presence of a test compound, said change indicating that the test compound modulates the function of pericytes and/or blood vessels. | 2009-05-14 |
20090123380 | METHOD OF ASSAYING SATIETY ENHANCING TASTANTS - Compositions for enhancing satiety and weight loss in an individual, assays for assessing a tastant for enhancing satiety and weight loss, and methods of using the composition to suppress appetite and enhance weight loss are provided. | 2009-05-14 |
20090123381 | IMAGING AND THERAPEUTIC TARGETING OF PROSTATE AND BLADDER TISSUES - The present invention provides methods for imaging and the treatment of cancer. In certain embodiments, a polyarginine (e.g., R11) may be used to selectively image prostate or bladder cells (e.g., a metastatic prostate cancer). In other embodiments, a DOC-2/DAB2 peptide, optionally conjugated to a cell permeable peptide (e.g., R11) may be used to treat a cancer, such as prostate cancer. | 2009-05-14 |
20090123382 | Light emitting microorganisms and cells for diagnosis and therapy of tumors - Provided are diagnostic and pharmaceutical compositions containing a microorganism or a cell containing a DNA molecule encoding a detectable protein or a protein that a detectable signal, such as a luminescent or fluorescent protein. Methods of tumor targeting and tumor imaging using the microorganisms and cells are provided. Also provided are therapeutic methods in which the microorganisms and cells, which can encoded a therapeutic protein, such as a cytotoxic or cytostatic protein, are administered. | 2009-05-14 |
20090123383 | Non-Isotopic Detection of Osteoblastic Activity In Vivo Using Modified Bisphosphonates - The present invention is directed to a non-isotopic methods for the in vitro and in vivo detection of hydroxyapatite-positive cells and structures. | 2009-05-14 |
20090123384 | METHOD FOR MAGNETIC RESONANCE IMAGING USING STIMULUS INDUCED ROTARY SATURATION WITH A CONTRAST AGENT - A method and system for producing an image of a subject with a magnetic resonance imaging (MRI) system, in which the presence of a contrast agent is detected using a spin-lock pulse sequence, is described. More specifically, a contrast agent that induces saturation of magnetic resonance signals responsive to a spin-lock condition is administered to a subject. A spin-lock condition is subsequently established to saturate spins in proximity to the contrast agent. Image data is then acquired with an imaging pulse sequence and images indicative of the presence of the contrast agent are reconstructed. | 2009-05-14 |
20090123385 | PREPARATION OF DISPERSIONS OF PARTICLES FOR USE AS CONTRAST AGENTS IN ULTRASOUND IMAGING - A method of making a suspension of particles in a first fluid of a size suitable for responding to ultrasound, by forcing a second fluid ( | 2009-05-14 |
20090123387 | BUCCAL, POLAR AND NON-POLAR SPRAY OR CAPSULE CONTAINING CARDIOVASCULAR OR RENEAL DRUGS - Buccal aerosol sprays or capsules using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal polar compositions of the invention comprise formulation I: aqueous polar solvent, active compound, and optional flavoring agent; formulation II: aqueous polar solvent, active compound, optionally flavoring agent, and propellant; formulation III: non-polar solvent, active compound, and optional flavoring agent; and formulation IV: non-polar solvent, active compound, optional flavoring agent, and propellant. | 2009-05-14 |
20090123388 | Prodrugs of Short-Chain Fatty Acids and Treatment Methods - Prodrugs made up of biologically-active short-chain fatty acids or derivatives thereof conjugated to neutral or cationic amino acids capable of intracellular transport by ATB | 2009-05-14 |
20090123389 | Methods for modulating Th17 cell development in the treatment and prevention of cellulite - This invention relates generally to methods and compositions for modulating the development of Th17 cells for use, for example, in the treatment of cellulite. | 2009-05-14 |
20090123390 | COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL INFLAMMATION - Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention. | 2009-05-14 |
20090123391 | Novel Formulations - A pharmaceutical aerosol formulation includes a therapeutically effective amount of particulate medicament of formula (I) or a solvate thereof, a propellant selected from the group consisting of 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoro-n-propane or mixtures thereof, and a biocompatible polymer comprising one or more compounds of formula (II) | 2009-05-14 |
20090123392 | FRAGRANCE ACCORDS TO COMBAT THE PERCEPTION OF BODY ODOR - The present invention concerns an accord, comprising, essentially consisting or consisting of:
| 2009-05-14 |
20090123393 | Multiphase Toothpaste Composition - Multiphase toothpaste composition comprising a first phase disposed co-axially within a second, visually clear gel phase, the second phase comprising from 1 ppm to 100 ppm of a pigment. | 2009-05-14 |
20090123394 | Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries - New strains of | 2009-05-14 |
20090123395 | Flavour Compositions - Flavor compositions which reduce or prevent dental cavities based on the use of flavor materials found to inhibit the production of acid by micro-organisms in the oral cavity, e.g. lactic acid production from glucose by | 2009-05-14 |
20090123396 | Anti-sensitivity,anti-caries, anti-staining, anti-plaque ultra-mild oral hygiene agent - This invention relates to a composition useful as a dentifrice comprising a surfactant agent consisting essentially of monoalkyl and dialkyl phosphate esters, wherein the ratio of monoesters to diesters is greater than 1, and optionally an abrasive agent consisting essentially of siliceous materials. | 2009-05-14 |
20090123397 | Microbiocidal compositions - A microbiocidal composition comprising: a non-halogenated 2-alkyl-3-isothiazolone, and chlorphenesin and/or an alkane diol, wherein the alkyl group in the non-halogenated 2-alkyl-3-isothiazolone comprises 1 to 4 carbon atoms, the alkane diol comprises from 5 to 12 carbon atoms, and the hydroxyl groups of the alkane diol are vicinally substituted. | 2009-05-14 |
20090123398 | SILICON-FREE HYDROCARBONS PROVIDING AESTHETIC VOLATILITY - Non-silicone-based compositions including hydrocarbons of widely different structures and origins are combined into single, stable, homogenous products with both aesthetic and volatility properties similar to a cyclopentasiloxane. The combinations are useful to cosmetic formulators as full or partial replacement products for cyclopentasiloxanes, or “volatile silicones.” | 2009-05-14 |
20090123399 | Packaged liquid edible composition comprising carotenoids - A packaged liquid edible composition comprising a blend of at least two species of fruit and/or vegetables in liquified, puree, pulp, concentrate, extract or juice form, wherein said composition is packaged in a container in an amount of a specific volume and having a specific consistency, and wherein said composition comprises carotenoids. | 2009-05-14 |
20090123400 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY - The present invention provides compositions and methods for decreasing photosensitivity induced by photodynamic therapy (PDT). The compositions and methods of the present method employ porphyrin complexing molecules as agents for reducing photosensitivity. | 2009-05-14 |
20090123401 | Method of Predicting Spot Formation on the Skin Using Spot Site-Accelerating Genes as an Indicator Thereof and Method of Screening Inhibitors of Spot Formation on the Skin - The present invention provides a skin test method for predicting the formation of spots in the skin. This method is characterized by judging skin to be susceptible to spot formation in the case expression of genes consisting of MLSTD1, MOGAT1, FADS2, FADS1, HSD3B1, ELOVL3, BG1, PECR, FABP7, FA2H, HAO2, ALOX15B, PDE6A, LZTS1, SEC14L4, BAMBI, CIDEA, TERE1, GAL, THRSP, INSIG1 or CUTL2 in the epidermis is accelerated, or the expression of genes consisting of RBBP6, MSMB, WIF1, ANKRD12, FLG, SYNE2, SCEL, NKTR or AMBP in the epidermis is decreased as compared with normal expression in the epidermis. | 2009-05-14 |
20090123402 | Lip Cosmetics - [Object] To provide lip cosmetics which are excellent in the sense of use such as smoothness and adhesion upon application, excellent in moisturizing and protecting properties for lips, and excellent in long-term stability. | 2009-05-14 |
20090123403 | Cosmetic Composition With Color And/Or Optical Effects - The present invention relates to a cosmetic process for making up and/or caring for keratin material(s), comprising the application, on contact with a keratin material, of at least one cosmetic composition consisting of at least 50% by weight, relative to its total weight, of compound(s) approved for food use, including at least particles with color and/or optical effects containing at least two materials, said particles being referenced in the Codex alimentarius or consisting exclusively of materials referenced in the Codex alimentarius. | 2009-05-14 |
20090123404 | FRAGRANCE COMPOSITION - Provided is a fragrance composition containing 8-drimanol represented by the formula (1a): | 2009-05-14 |
20090123405 | Hair Shine and Styling Hold Composition And Methods Of Forming And Using Same - A hair styling and shine composition and methods of using and forming the composition are disclosed. The composition includes about 0.1 wt % to about 60 wt % of a volatile silicone, about 0.1 wt % to about 20% wt % of hair fixative resin, and about 40 wt % to about 85% wt % of an organic solvent. | 2009-05-14 |
20090123406 | ORGANIC THERAPEUTIC AND COSMETIC PREPARATION - A mixture of an aqueous solution, essential oils and mechanically extracted Phaeophyte kelp cytoplasm results in an emulsion with cosmetic and therapeutic properties. The preparation may be used on human and animal hair or skin. The moisturizing properties of the kelp cytoplasm provide the aqueous solution to the hair (keratin) which is absorbed, causing the hair to swell, and become heavier and more pliable. The natural oxidation agent preserves the mixture as well as providing a fresh oxygen in a spray when used. The alginate gels and oils in the emulsion coat the hair strands to reduce breakage and splitting and add weight to the strand. The preparation dries with gel capsules, which release moisture over time for a long-lasting effect. The preparation also contains, and may be supplemented with fuciodans, iodine, phlorotannins which reduce inflammation, prevent scaly skin, and act as an antibiotic, respectively, on dry chapped skin. The preparation seals off the cracks from the environment while trapping moisture pockets. This provides an environment conducive for healing. | 2009-05-14 |
20090123407 | MONO-, DI- AND POLYOL PHOSPHATE ESTERS IN PERSONAL CARE FORMULATIONS - A hydrophilized personal care formulation, which can be in the form of a hand or body soap (liquid or bar), lipstick, body wash, makeup remover, skin cleaner, hair conditioner, skin or hair moisturizer. The formulation employs an organophosphorus material or a mixture of an organophosphorus material, for example, mono-, di-, and polyol phosphate esters. | 2009-05-14 |
20090123408 | Polymer And Cosmetic Preparation - The present invention provides a novel polymer that can impart a moisturized feeling to the hair and skin after use. A polymer comprising an amphoteric monomer represented by the following general formula (I) and a cationic monomer represented by the following general formula (II) as the essential constituent monomers: | 2009-05-14 |
20090123409 | ENHANCED SHAVING COMPOSITIONS - A method for treating human skin comprising a shaving composition consisting of algae extract, willow bark extract, de-ionized water, propylene glycol, aloe vera, guar gum, diazolidinyl urea, and iodopropynyl butylcarbamate. The method further comprising applying the shaving composition to the skin prior to shaving the skin. | 2009-05-14 |
20090123410 | KERATOTIC PLUG REMOVING COMPOSITION - The present invention relates to a keratotic plug remover composition including a polymer compound having a salt-forming group, and (a) an amino-modified silicone and/or (b) a polyoxyalkylene/dimethyl polysiloxane block copolymer, and a sheet for removing keratotic plugs including a nonwoven fabric substrate impregnated with the above composition. The keratotic plug remover composition and the sheet for removing keratotic plugs according to the present invention are enhanced in keratotic plug removing effect without increasing a pain of users when peeling the sheet pack from the skin. | 2009-05-14 |
20090123411 | Molecular Fingerprints With Enhanced Identifying Capability, Method for Preparing Same and Use Thereof - The invention concerns a method for preparing a molecular fingerprint comprising sites for identifying at least one target molecule, said fingerprint being obtained from at least one master molecule of polymeric type, called master polymer. The invention is characterized in that said master polymer is different from the target molecule(s), and is capable of being eliminated by degradation and/or washing, and that at least 5% in number of monomer units constituting the master polymer are involved in the formation of the sites for identifying the target molecule(s). | 2009-05-14 |
20090123412 | Methods and compositions for stabilizing the myocardium - The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium. | 2009-05-14 |
20090123413 | USE OF BAT MONOCLONAL ANTIBODY FOR IMMUNOTHERAPY - The present invention relates to immunotherapy and more specifically concerns the use of immunostimulatory BAT monoclonal antibodies for treatment of a variety of immunodeficiency related diseases and disorders and malfunction or incompetence of the immune system. | 2009-05-14 |
20090123414 | Il-15 Antigen Arrays And Uses Thereof - The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen array, wherein the antigen is an IL-15 protein, an IL-15 mutein or an IL-15 fragment. More specifically, the invention provides a composition comprising a virus-like particle, and at least one IL-15 protein, IL-15 mutein or at least one IL-15 fragment linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of inflammatory and chronic autoimmune diseases. The composition of the invention efficiently induces immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context. | 2009-05-14 |
20090123415 | DIAGNOSIS, TREATMENT, AND PREVENTION OF VASCULAR DISORDERS USING IL-1 AUTOANTIBODIES - Methods of detecting individuals at risk for atherosclerosis and related vascular diseases involving the detection of IL-1α autoantibodies, as well as therapeutic methods to prevent or treat atherosclerosis and related vascular disease by administering a pharmaceutical composition comprising IL-1α autoantibodies. | 2009-05-14 |
20090123416 | METHODS FOR THE TREATMENT OF BLADDER CANCER USING 3-(4-AMINO-1-OXO-1,3-DIHYDROISOINDOL-2-YL)-PIPERIDINE-2,6-DIONE - Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed. | 2009-05-14 |
20090123417 | RECOMBINANT SUPER-COMPOUND INTERFERON AND USES THEREOF - This invention provides a recombinant super-compound interferon (rSIFN-co) and its equivalent with changed spatial configuration, high efficacy and low side effects. Therefore, high dose of rSIFN-co may be used. One characteristic of rSIFN-co is its ability to inhibit the HBV DNA duplication and secretion of HBsAg and HBeAg in in vitro pharmacological studies. The cytotoxic effect of rSIFN-co is only one-eighth (⅛) of currently clinically available interferons but its anti-viral effect is approximately five to twenty (5-20) times higher, and when used in vivo it has a broader spectrum of clinical applications and longer biofeedback response. This invention further provides super-compound interferon or its equivalent, synthesis of artificial gene with codon preference which codes for said rSIFN-co and its equivalent, vector comprising said gene and appropriate expression system for expression of said rSIFN-co. Finally this invention provides the super-compound interferon (rSIFN-co) and its equivalent, a process to produce same and uses thereof. | 2009-05-14 |
20090123418 | METHODS OF ADMINISTERING N-(5-TERT-BUTYL-ISOXAZOL-3-YL)-N'-UREA TO TREAT PROLIFERATIVE DISEASE - Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt or solvate thereof, to human patients. Specifically, dosing, dosing schedules or dosing regimens are provided herein. Further, pharmaceutical formulations are provided. Methods of treating proliferative diseases or FLT-3 mediated diseases in humans are also provided. | 2009-05-14 |
20090123419 | TREATMENT OF UTERINE CANCER AND OVARIAN CANCER WITH A PARP INHIBITOR ALONE OR IN COMBINATION WITH ANTI-TUMOR AGENTS - In one aspect, the present invention provides a method of treating uterine cancer, endometrial cancer, or ovarian cancer, comprising administering to a subject at least one PARP inhibitor. In another aspect, the present invention provides a method of treating uterine cancer, endometrial cancer, or ovarian cancer, comprising administering to a subject at least one PARP inhibitor in combination with at least one anti-tumor agent. | 2009-05-14 |
20090123420 | Regulation of T Cell-Mediated Immunity by D Isomers of Inhibitors of Indoleamine-2,3-Dioxygenase - The present invention provides improved treatment methods by the administration of the non-physiologic D-isomer of an IDO inhibitor. | 2009-05-14 |
20090123421 | ANTI-LYMPHOTOXIN-BETA RECEPTOR ANTIBODIES AS ANTI-TUMOR AGENTS - This invention relates to compositions and methods useful for activating LT-β receptor signaling, which in turn elicits potent anti-proliferative effects on tumor cells. More particularly, this invention relates to lymphotoxin heteromeric complexes formed between lymphotoxin-a and multiple subunits of lymphotoxin-β, which induce cytotoxic effects on tumor cells in the presence of lymphotoxin-β receptor activating agents. Also within the scope of this invention are antibodies directed against the lymphotoxin-β receptor which act as lymphotoxin-β receptor activating agents alone or in combination with other lymphotoxin-β receptor activating agents either in the presence or absence of lymphotoxin-a/β complexes. A screening method for selecting such antibodies is provided. This invention also relates to compositions and methods using cross-linked anti-lymphotoxin-β receptor antibodies either alone or in the presence of other lymphotoxin-β receptor activating agents to potentiate tumor cell cytotoxicity. | 2009-05-14 |
20090123422 | Method of treating idiopathic pulmonary fibrosis with aerosolized IFN-y - A method of treating idiophathic pulmonary fibrosis (IPF), comprising administering aerosolized interferon-γ in a therapeutically effective amount to achieve improved or ameliorated symptoms of IPF. | 2009-05-14 |
20090123423 | HYDROXYAMIC ANALOGS AS HEPATITIS C VIRUS SERINE PROTEASE INHIBITOR - The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: | 2009-05-14 |
20090123424 | Methods of protein purification and recovery - Improved methods for purification and recovery of interferon-beta (IFN-β) and compositions comprising substantially monomeric IFN-β are provided. In one purification method, substantially purified IFN-β or variant thereof is precipitated and then dissolved in a guanidine hydrochloride (HCl) solution. Renaturation of the protein occurs by dilution with a suitable buffer. A similar purification method absent the precipitation step is also provided. Following renaturation of the IFN-β residual guanidine HCl is removed by diafiltration or dialysis with a pharmaceutically acceptable buffer to prepare pharmaceutical compositions comprising substantially monomeric IFN-β. | 2009-05-14 |
20090123425 | MACROCYCLIC, PYRIDAZINONE-CONTAINING HEPATITIS C SERINE PROTEASE INHIBITORS - The present invention relates to compounds of Formula I, II, or III, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 2009-05-14 |
20090123426 | Compositions for Bacterial Mediated Gene Silencing and Methods of Using the Same - Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating cancer off cell proliferative disorders. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells. | 2009-05-14 |
20090123427 | Method of Treating a Malignancy in a Subject and a Pharmaceutical Composition for Use in Same - There is a disclosed a method of killing abnormal cells such as malignant cells including melanoma cells, using a virus recognising at least one of a cell adhesion molecule and a complement regulatory protein. The virus may be a member of the Picornaviridae family. Coxsackie A-group viruses have been found to be particularly suitable. The cell adhesion molecule is desirably a member of the immunoglobulin (Ig) superfamily. Typically, the complement regulatory protein will be DAF. | 2009-05-14 |