18th week of 2011 patent applcation highlights part 61 |
Patent application number | Title | Published |
20110105688 | POLYROTAXANE, CROSSLINKED STRUCTURE COMPRISING POLYROTAXANE AND POLYMER, AND PROCESSES FOR PRODUCING THESE - A process is provided by which a polyrotaxane including cyclic molecules having a relatively long graft chain is easily obtained. Also provided is a polyrotaxane which includes cyclic molecules having a radical polymerization initiation site and is for use as a raw material in the process. The polyrotaxane comprises: a pseudo-polyrotaxane comprising cyclic molecules clathrated with a linear molecule, the cavities of the cyclic molecules having been pierced by the linear molecule; and blocking groups disposed respectively at both ends of the pseudo-polyrotaxane so as not to release the cyclic molecules. The cyclic molecules in the polyrotaxane have a radical polymerization initiation site. | 2011-05-05 |
20110105689 | COMPOSITION FOR CROSSLINKABLE POLYIMIDE PRECUSOR, METHOD OF MANUFACTURING CROSS-LINKED POLYIMIDE, AND POLYIMIDE FILM - A polyimide precursor composition includes an oligomer or polymer having a substituted or unsubstituted carbonyl group only in a side chain and a diamine compound. A method of manufacturing a polyimide, and a polyimide film, are also disclosed. | 2011-05-05 |
20110105690 | Method for Making Propylene Impact Copolymers with Balanced Impact Strength and Stiffness - Disclosed is a propylene impact copolymer comprising a first polypropylene having an MFR | 2011-05-05 |
20110105691 | Blends of Polypropylene and Polyethylene and Methods of Forming the Same - Polymer blends and methods of forming the same are described herein. The polymer blends generally include a single site transition metal catalyst formed polypropylene, a single site transition metal catalyst formed polyethylene and a polyethylene compatible nucleator. | 2011-05-05 |
20110105692 | NITRILE GROUP-CONTAINING HIGHLY SATURATED COPOLYMER RUBBER - A nitrile group-containing highly saturated copolymer rubber having α,β-ethylenically unsaturated nitrile monomer units (a) and conjugated diene monomer units (b) and having at least part of said conjugated diene monomer units (b) hydrogenated, wherein a content of said α,β-ethylenically unsaturated nitrile monomer units (a) is 37 to 45 wt %, a total of said α,β-ethylenically unsaturated nitrile monomer units (a) and said conjugated diene monomer units (b) is 93 wt % or more, an iodine value is 9 or less, and a half value width of a peak of a loss tangent (tanδ) in the viscoelastic properties when made into a cross-linked product is 5 to 20° C. in range. | 2011-05-05 |
20110105693 | CATIONIC TRANSITION-METAL ARENE CATALYSTS - Disclosed are cationic ruthenium arene complexes of Formula (I): [Ru(D-Z | 2011-05-05 |
20110105694 | HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF - A hydrogenation catalyst composition for hydrogenating a polymer of conjugated diene is provided. The polymer of conjugated diene is a homopolymer of conjugated diene or a copolymer of conjugated diene and vinyl aromatics. The hydrogenation catalyst composition includes: (a) a titanium compound, (b) a compound of formula (II), | 2011-05-05 |
20110105695 | Method for making Plas stereocomplexes - PLA stereocomplexes are formed from poly-D-PLA and poly-L-PLA oligomers. The oligomers contain functional groups which allow them to react with each other or with an added curing agent to produce a high molecular weight block copolymer. Heat treatment of the resin permits the resin to develop crystallites having a melting temperature of 185° C. or more. | 2011-05-05 |
20110105696 | Resin System With Carbon Additive - The gel time of a grouting system may be controlled by providing a resin component separated by a catalyst component, where a carbon component is included in the catalyst component. The catalyst component may include an inhibitor such as a phenolic compound, and/or the resin component may include a promoter such as an aniline compound. | 2011-05-05 |
20110105697 | POLYAMIDE MOULDED MASSES CONTAINING SEMI-CRYSTALLINE TRANSPARENT COPOLYAMIDES FOR PRODUCING HIGH FLEXIBLE TRANSPARENT MOULDED PARTS WITH HIGH NOTCH-IMPACT STRENGTH, LOW WATER ABSORBENCY AND EXCELLENT RESISTANCE TO CHEMICALS - The invention relates to polyamide moulded masses based on semi-crystalline, transparent copolyamides predominantly based on aliphatic monomers, for producing transparent or pigmentable moulded parts with a high level of flexibility, high notch-impact strength (Charpy), low water absorbency and excellent resistance to chemicals, containing between 40 and 100 wt. % of at least one transparent copolyamide (constituent A) with a maximum glass transition temperature (Tg) of 80° C. and a melting temperature of at least 150° C., and a melting enthalpy of at least 20 J/g, preferably at least 30 J/g, consisting of at least two different diamines selected from the group consisting of linear and/or branched-chain aliphatic diamines with between 9 and 14 carbon atoms and cycloaliphatic diamines, especially between 6 and 36 carbon atoms, the concentration of cycloaliphatic diamine being between 10 and a maximum of 40 mol % and the concentration of aliphatic diamine at least 60 mol %, respectively in relation to the total diamine content, and of at least one aliphatic dicarboxylic acid, especially between 6 and 36 carbon atoms, and between 0 and 60 wt. % of at least one other polymer (constituent B) selected from the group consisting of amorphous or semi-crystalline homopolyamides or copolyamides, polyether ester amides, polyether amides, polyester amides or mixtures thereof, between 0 and 10 wt. % of other additives (constituent C) selected from the group consisting of UV stabilisers, heat stabilisers, free-radical scavengers and/or processing auxiliary agents, inclusion inhibitors, lubricants, mould-release auxiliary agents, softeners, functional additives for influencing optical properties, especially the refractive index, impact-resistant modifiers, nanoscale fillers and/or loaders, optical brighteners, dyes or mixtures thereof, the constituents (A), (B) and (C) amounting to 100 wt. %. | 2011-05-05 |
20110105698 | ALIGNMENT MATERIAL FOR LIQUID CRYSTAL DISPLAY DEVICE OF VERTICAL ALIGNMENT MODE AND METHOD OF PREPARING THE SAME - This invention provides alignment materials for liquid crystal display device of vertical alignment mode and methods for the preparation of the same, and more particularly, it provides diaminobenzene derivatives represented by the following formula 1 (shown in description), capable of aligning liquid crystal in uniform and vertical way and remarkably improving clarity and solubility against organic solvents, methods for the preparation of the same and liquid crystal alignment films using the same. | 2011-05-05 |
20110105699 | AROMATIC POLYESTER RESIN COMPOSITION - An aromatic polyester resin composition, including: a melt-kneaded product of 99-70 wt. parts of an aromatic polyester resin and 1-30 wt. parts (providing a total of 100 wt. parts together with the aromatic polyester resin) of a polyglycolic acid resin, wherein the aromatic polyester resin is an aromatic polyester resin polymerized with a germanium compound (catalyst), and the polyglycolic acid resin is a polyglycolic acid resin obtained by ring-opening polymerization of glycolide. As a result, gas generation during the melt-processing of a composition obtained by adding a relatively small amount of polyglycolic acid resin to an aromatic polyester resin is effectively suppressed to provide an aromatic polyester resin composition with a good gas-barrier property. | 2011-05-05 |
20110105700 | LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE - The present invention relates to a liquid crystal aligning agent containing a radiation sensitive polyorganosiloxane which is obtained by reacting at least one selected from the group consisting of a polyorganosiloxane having a recurring unit represented by the following formula (1), a hydrolysate thereof and a condensate of the hydrolysis with a cinnamic acid derivative having at least one group selected from the group consisting of a carboxyl group, a hydroxyl group, —SH, —NCO, —NHR (R is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms), —CH═CH | 2011-05-05 |
20110105701 | Dynamic Pressure Control in Double Loop Reactor - The present invention discloses a slurry loop reactor comprising at least two loop reactors connected in series and wherein the line connecting the two loops is subject to a dynamic pressure difference. | 2011-05-05 |
20110105702 | OLEFIN POLYMERISATION PROCESS - A continuous process for manufacturing a polyolefin resin in at least two reactors in series is described, in which: in a first polymerisation reactor, an olefin is polymerised continuously in the presence of a catalyst and a diluent to produce a first suspension comprising the diluent and polyolefin particles; at least a portion of said first suspension is transferred from the first polymerisation reactor to a second polymerisation reactor where further polymerisation takes place; a further suspension comprising diluent and polymer particles is withdrawn from the second reactor and transferred to two separators, in each of which separators a diluent-rich flow and a concentrated suspension of polyolefin particles are formed and separated, wherein the diluent-rich flow from one separator is recycled to a reactor preceding the second reactor, and the diluent-rich flow from the other separator is recycled to the second reactor. The invention enables higher separator efficiencies to be achieved. | 2011-05-05 |
20110105703 | PROCESS FOR PRODUCTION OF POLYMERS WITH IRON COMPLEX CATALYST - The invention relates to a novel iron complex bearing a cyclic amine as ligand; and a process for the production of polymers by polymerizing a radical-polymerizable monomer in the presence of the iron complex and a radical generator. The invention aims at providing a process by which a polymer having a chemically convertible functional group at the end can be produced from a radical-polymerizable monomer and which permits the production of a block copolymer and a process for recovering, after polymerization, an iron complex into a solvent at a high recovery ratio. The aim can be solved by providing a novel iron complex, a process for producing a polymer in the presence of a radical polymerization initiator by using the iron complex as the polymerization catalyst, a process for the production of a block copolymer which is subsequent to the polymerization for producing the above polymer, and a process for recovering the iron complex easily and simply. The invention provides an iron complex useful in producing a polymer by polymerizing a radical-polymerizable monomer; and a process for the production of polymers with the iron catalyst. | 2011-05-05 |
20110105704 | Sterically Emcumbered Bidentate and Tridentate Naphthoxy-Imine Metallic Complexes - The present invention discloses post-metallocene complexes based on sterically encumbered bi- and tri-dentate naphthoxy-imine ligands. It also relates to the use of such post-metallocene complexes in the oligomerisation of ethylene to selectively prepare vinyl-end capped linear alpha-olefins. | 2011-05-05 |
20110105705 | Metallocene Supported Catalyst Composition and a Process for the Preparation of Polyolefin Using the Same - The invention relates to a metallocene supported catalyst composition and a process for the preparation of polyolefin using the same. A metallocene supported catalyst composition according to the invention is prepared by bringing a compound of a group IV transition metal into contact with an inorganic or organic porous carrier treated with an ionic compound. Advantages of a metallocene supported catalyst composition of the invention include an increase in the catalyst activity during polymerization of slurry and an olefin compound in the vapor phase even at a low content of metallocene metal components within the carrier, and an improvement in solving process problems such as fouling, sheeting, plugging or the like. | 2011-05-05 |
20110105706 | ENERGY EFFICIENT SYNTHESIS OF BORANES - The reaction of halo-boron compounds (B—X compounds, compounds having one or more boron-halogen bonds) with silanes provides boranes (B—H compounds, compounds having one or more B—H bonds) and halosilanes. Inorganic hydrides, such as surface-bound silane hydrides (Si—H) react with B—X compounds to form B—H compounds and surface-bound halosilanes. The surface bound halosilanes are converted back to surface-bound silanes electrochemically. Halo-boron compounds react with stannanes (tin compounds having a Sn—H bond) to form boranes and halostannanes (tin compounds having a Sn—X bond). The halostannanes are converted back to stannanes electrochemically or by the thermolysis of Sn-formate compounds. When the halo-boron compound is BCl | 2011-05-05 |
20110105707 | Method for the Production of Water-Absorbing Polymer Articles by Polymerizing Drops of a Monomer Solution - A process for producing water-absorbing polymer particles by polymerizing droplets of a monomer solution in a surrounding gas phase, wherein the monomer solution comprises at least | 2011-05-05 |
20110105708 | PROCESS FOR MANUFACTURING REDUCED WATER CONTENT (METH)ACRYLIC ACID - A method is provided herein for purifying (meth)acrylic acid to provide a purified (meth)acrylic acid product having a low aldehyde concentration and not more than 0.2 wt % water. One embodiment of the method includes distilling (meth)acrylic acid in the presence of an aldehyde treating compound. Another embodiment of the method includes also distilling crude (meth)acrylic acid in the presence of a reactive drying agent. (Meth)acrylic acid produced in this manner is especially suitable for use in specialty (meth)acrylic acid polymers, such as for example superabsorbent polymers, binders, and ethylene-(M)AA copolymers. | 2011-05-05 |
20110105709 | WATER-SOLUBLE ACRYLIC ACID SALT POLYMER AND GELLING BASE - The present invention provides a water-soluble acrylate polymer that makes it possible to obtain a gelling base having a gel strength recited below when the gelling base comprises the components and the proportions thereof listed below;
| 2011-05-05 |
20110105710 | OPTICAL RESIN, OPTICAL RESIN COMPOSITION, OPTICAL FILM, AND FILM - An optical resin comprises a copolymer of 4-methyl-1-pentene and at least one monomer selected from the group consisting of 3-methyl-1-pentene, 3-methyl-1-butene and 4,4-dimethyl-1-pentene. The content of a constituent unit (a) derived from 4-methyl-1-pentene is equal to or more than 60 mol % and equal to or less than 99 mol %, and the total content of a constituent unit (b) derived from at least one monomer selected from the group consisting of 3-methyl-1-pentene, 3-methyl-1-butene and 4,4-dimethyl-1-pentene is equal to or more than 1 mol % and equal to or less than 40 mol %. | 2011-05-05 |
20110105711 | CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS AND CONJUGATED OLIGOMERS OR POLYMERS BASED THEREON - Crosslinkable substituted fluorine compounds; oligomers and polymers prepared from such crosslinkable compounds; films and coatings; and multilayer electronic devices comprising such films are disclosed. | 2011-05-05 |
20110105712 | ZWITTERIONIC POLYMERS HAVING BIOMIMETIC ADHESIVE LINKAGES - Zwitterionic polymers having adhesive groups, methods for making the polymers, surfaces having the polymers grafted thereto and grafted therefrom, and methods for making and using the polymer-modified surfaces. | 2011-05-05 |
20110105713 | ISOCYANURIC RING-CONTAINING POLYSILOXANE HAVING VINYL GROUPS AT THE TERMINALS - The purpose of the present invention is to provide an isocyanuric ring-containing organopolysiloxane which can provide a cured product which can exploit the properties of a hydrosilylation (addition reaction), and is suitable for use in an encapsulating materials for an optical semiconductor. Thus, the present invention provides an organopolysiloxane having at least one isocyanuric ring in a molecule and vinyl siloxy groups at both terminals, and represented by the following formula (1): | 2011-05-05 |
20110105714 | METHOD FOR PRODUCING POLYOLS - A process for the preparation of a polyol which includes reacting an amino-group-containing starter compound with an alkylene oxide in the presence of a catalyst to form a polyol, wherein the catalyst is based on a compound selected from the group consisting of alkali metal hydroxides, alkali, alkaline earth metal hydrides, alkaline earth metal carboxylates, and alkaline earth hydroxides, and wherein the catalyst is present in an amount of from 0.004 to 0.1 wt. % based on the amount of polyol; and neutralizing the polyol with from 0.75 to 1 mol of sulfuric acid per mol of catalyst used. | 2011-05-05 |
20110105715 | Titanium Oxide Composition and the Application Thereof on Poly-Esterification - The application discloses a Titanium oxide composition and the application thereof. The mentioned Titanium oxide composition comprises Titanium co-precipitate(s), organic acid, diol, and water. According to this application, a catalyzed poly-esterification with said Titanium oxide composition is also disclosed. The mentioned polyesterification comprises a step of adding said Titanium oxide composition into at least one stage selected from slurry stage, esterification stage, and polycondensation stage. | 2011-05-05 |
20110105716 | PROCESS AND APPARATUS FOR PREPARING BIOPOLYMERS - In a method of treating viscous products, particularly for the implementation of polymerization operations, more particularly for the homopolymerization or copolymerization of bipolymers, where monomer(s) and/or catalysts and/or initiators are fed to a backmixed mixing compound ( | 2011-05-05 |
20110105717 | METHOD FOR SYNTHESIZING THIOPHENES - Process for preparing thiophenes useful for the preparation of semiconductive polymers or semiconductive oligomers with a defined mean molar mass and a narrow molecular mass distribution. | 2011-05-05 |
20110105718 | NEL-RELATED PROTEIN TYPE 1 ANTIBODY - The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases. | 2011-05-05 |
20110105719 | REACTOR FOR PRODUCING PHARMACEUTICAL PARTICLES IN A PRECIPITATION PROCESS - Reactors, reactor systems and methods for producing particles in a precipitation process are provided. The reactor includes a housing defining a reaction chamber, a stator assembly including two or more stators, a rotor assembly including two or more rotors, the rotor assembly configured for rotation about an axis of rotation relative to the stator assembly, a first inlet to supply a first reactant material to the reaction chamber at a first radial location, a second inlet to supply a second reactant material to the reaction chamber at a second radial location different from the first radial location, wherein the first and second reactant materials react to produce precipitation of particles in the reaction chamber, and an outlet to supply the particles formed in the reaction chamber. | 2011-05-05 |
20110105720 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES - Novel acylated insulin analogues exhibiting resistance towards proteases can, effectively, be administered pulmonary or orally. The insulin analogues contain B25H and A14E or A14H. | 2011-05-05 |
20110105721 | PEPTIDES - Isolated peptides that are fragments of protein products arising from frameshift mutations in genes associated with cancer are disclosed. The isolated peptides of the invention are capable of eliciting T cell immunity against cells harboring genes with such frameshift mutations. Cancer vaccines and therapeutically effective compositions containing the peptides of the inventions are also described. | 2011-05-05 |
20110105722 | Peptide synthesis method using n-carboxyanhydride (UNCA) - Method for preparing a peptide or a peptide derivative which comprises it least one step in which a free amino acid or a free peptide is reacted with a urethane-protected amino acid N-carboxyanhydride (UNCA) solution. | 2011-05-05 |
20110105723 | Method of Detecting Malignancy of Nasopharyngeal Carcinoma and A Nasopharyngeal Carcinoma Malignancy Biomarker - A method of detecting malignancy of nasopharyngeal carcinoma and a nasopharyngeal carcinoma malignancy biomarker are disclosed. Firstly, a specimen is obtained from a testee. Next, the specimen is tested for its MIP-3α expression level. Then, the MIP-3α expression level of the specimen is compared with that of a control. Finally, the malignancy of nasopharyngeal carcinoma is determined according to a relative MIP-3α expression level between the specimen and the control. | 2011-05-05 |
20110105724 | NOVEL COMPOUNDS - The present invention relates to neutralizing antibodies (immunoglobulins) which are specific for human IL-8 and bind to as well as neutralize human IL-8. | 2011-05-05 |
20110105725 | ANTIBODY PURIFICATION PROCESS - The invention concerns a method for the industrial production of antibodies. | 2011-05-05 |
20110105726 | ANTIBODIES TO HSDEK49 POLYPEPTIDES - The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating immune disorders and diseases. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention. | 2011-05-05 |
20110105727 | Method for the humanization of antibodies and humanized antibodies thereby obtained - Method for the humanization of the VII and VL variable regions of an animal antibody of known sequence, humanized animal antibody obtainable according to the method, in particular anti-NGF and anti-TrkA humanized animal antibodies. | 2011-05-05 |
20110105728 | METHOD FOR THE HUMANIZATION OF ANTIBODIES AND HUMANIZED ANTIBODIES THEREBY OBTAINED - Method for the humanization of the VH and VL variable regions of an animal antibody of known sequence, humanized animal antibody obtainable according to the method, in particular anti-NGF and anti-TrkA humanized animal antibodies. | 2011-05-05 |
20110105729 | BINDING DOMAIN-IMMUNOGLOBULIN FUSION PROTEINS - The invention relates to novel binding domain-immunoglobulin fusion proteins that feature a binding domain for a cognate structure such as an antigen, a counterreceptor or the like, a hinge region polypeptide having either zero or one cysteine residue, and immunoglobulin CH2 and CH3 domains, and that are capable of ADCC and/or CDC while occurring predominantly as monomeric polypeptides. The fusion proteins can be recombinantly produced at high expression levels. Also provided are related compositions and methods, including immunotherapeutic applications. | 2011-05-05 |
20110105730 | AFFINITY CHROMATOGRAPHY MATRICES AND METHODS OF MAKING AND USING THE SAME - The invention provides methods of coupling protein ligands to a solid support. The invention also provides affinity chromatography matrices and methods of using affinity chromatography matrices to purify a target molecule. | 2011-05-05 |
20110105731 | Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon - Provided herein are antibodies, fragments and derivatives of an antibody containing a binding domain thereof, where the antibody, fragment or derivative specifically binds to a single chain protease domain of a type II transmembrane serine protease (MTSP). Methods using the antibodies to modulate the protease activity of an MTSP are provided. Also provided are antibodies that bind to MTSPs designated MTSP3 and MTSP4 and to a form of an MTSP designated MTSP6. | 2011-05-05 |
20110105732 | Reagents for the Detection of Protein Phosphorylation in Carcinoma Signaling Pathways - The invention discloses 214 novel phosphorylation sites identified in signal transduction proteins and pathways underlying human carcinoma, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. Among the phosphorylation sites identified are sites occurring in the following protein types: Adaptor/Scaffold proteins, Cytoskeleton proteins, GTP Signaling proteins, Kinases, Metabolism proteins, Phosphatases/Phospho-diesterases/Proteases, Receptor proteins, RNA Processing proteins, Transcription proteins, Translation proteins, Transporter proteins, and Ubitquitin proteins, as well as other protein types. | 2011-05-05 |
20110105733 | SINGLE VARIABLE DOMAINS AGAINST THE NOTCH PATHWAYS - The present invention relates to amino acid sequences (also referred to herein as “single variable domain(s) of the invention”. “Nanobody™ of the invention” or “Nanobodies™ of the invention”, ilpolypeptide(s) of the invention”) that are directed against (as defined herein) members of the Notch signalling pathway such as the four mammalian members of the Notch Receptors (Notch-1, Notch-2, Notch-3, Notch-4, hereinafter also “Notch Receptors”) and the five mammalian members of the Notch Ligands (the Delta-like family with “DLL1”, “DLL3”, “DLL4” wherein “DLL” stands for Delta-like ligand; the Jagged family with “Jagged-1”, “Jagged-2”, hereinafter also “Notch Ligands”), as well as to constructs that comprise or essentially consist of one or more such single variable domain(s) (also referred to herein as “construct of the invention” and “constructs of the invention”, “Nanobody™ of the invention” or “Nanobodies™ of the invention”, respectively). In particular, this invention relates to Notch pathway interfering single variable domains down- or up-regulating Notch signaling (also referred to herein “Notch-antagonists” or “Notch-agonists”). | 2011-05-05 |
20110105734 | METHOD FOR PRODUCTION OF HUMAN ERYTHROPOIETIN - Disclosed is a method for production of human erythropoietin. By the method, the cells are cultured in a serum-free medium with repetitive medium exchanges, in which medium exchange is carried out either by collecting 80 to 95% of the culture when viable cell density has reached at 2×10 | 2011-05-05 |
20110105735 | METHODS OF PRODUCING AND PURIFYING PROTEINS - Methods of producing and purifying proteins that comprise a glycan tag are provided. In some embodiments, a protein may be modified to include a glycan tag so as to facilitate production of the protein, e.g., by promoting protein secretion and/or promoting protein solubility. In some embodiments, the present disclosure provides methods wherein a protein may be modified to include a glycan tag, which may then be used as an affinity tag for purification. | 2011-05-05 |
20110105736 | SEPARATING AGENT FOR PROTEIN PURIFICATION AND PROTEIN PURIFICATION METHOD - A novel separating agent for protein purification which not only can adsorb proteins in a sufficient amount for protein purification from a low concentration buffer but also can desorb the adsorbed protein easily just by altering the pH of the buffer and a simple and economical method for its production and a method for protein purification using it. | 2011-05-05 |
20110105737 | METHOD FOR PRETREATING PLANT STARTING MATERIAL FOR THE PRODUCTION, FROM SACCHARIFEROUS AND LIGNOCELLULOSIC RESOURCES, OF BIOETHANOL AND OF SUGAR, AND PLANT - A method for pretreating plant starting material for the purpose of producing bioethanol and/or sugar via a common chamber ( | 2011-05-05 |
20110105738 | DIARYL HEPATONOID-BASED COMPOUNDS USEFUL AS VIRUS INHIBITORS - The present invention relates to the use of diaryl hepatonoid-based compounds of formula (1) for inhibiting viral activity. The diaryl hepatonoid-based compounds have an excellent effect of inhibiting viral activity, and thus will be useful as therapeutic agents against virus-related diseases. | 2011-05-05 |
20110105739 | NOVEL MATRIX MATERIALS, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF IN METHODS FOR ISOLATING BIOMOLECULES - The invention relates to functionalized matrix materials or matrices that have structures of general formula (I) T-(C═O)O—B-D, methods for the production thereof, and the use thereof in methods for purifying and isolating biomolecules. | 2011-05-05 |
20110105740 | SOLUBLE TNF RECEPTORS AND THEIR USE IN TREATMENT OF DISEASE - The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of inflammatory diseases. These proteins are soluble secreted decoy receptors that bind to TNF and prevent TNF from signaling to cells. In particular, the proteins are mammalian TNFRs that lack exon 7 and which can bind TNF and can act as a TNF antagonist. | 2011-05-05 |
20110105741 | NUCLEIC ACIDS ENCODING A G-PROTEIN COUPLED RECEPTOR INVOLVED IN SENSORY TRANSDUCTION - The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors. | 2011-05-05 |
20110105742 | Optimized DNA Sequence Of An Antibody To Improve Quality And Yield Of Bacterially Expressed Antibody Fusion Proteins - Object matter of the invention is an optimized DNA sequence encoding the scFv(FRP5) antibody fragment. This novel sequence prevents the generation of the undesired by-product in the context of an scFv(FRP5)-ETA fusion protein, and possibly also other bacterially expressed scFv(FRP5)-containing fusion proteins. The DNA sequence of the scFv(FRP5) domain of scFv(FRP5)-ETA was modified by exchanging a distinct codon, thereby preventing an otherwise possible internal start of protein translation. | 2011-05-05 |
20110105743 | IMPROVED METHOD AND PROCESS FOR SYNTHESIS OF 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES - A method is disclosed for synthesizing 2′,3′-didehydro-2′,3′-dideoxynucleosides (d4Ns) from a nucleophile-mediated elimination, such as a telluride-mediated elimination reaction. After substitution of 2,2′-anhydronucleosides with a nucleophile, such as a telluride monoanion, a telluride intermediate is formed, and its elimination leads to formation of the olefin products (d4Ns). This disclosure describes this telluride-assisted (or nucleophile-assisted) reaction and how to facilitate the substitution and elimination in order to form d4Ns. | 2011-05-05 |
20110105744 | METHOD FOR GLYCOSYLATING AND SEPARATING PLANT FIBER MATERIAL - The invention relates to a method for hydrolyzing a plant fiber material and producing and separating a saccharide including glucose. The method of the invention includes a hydrolysis process of using a cluster acid catalyst in a pseudo-molten state to hydrolyze cellulose contained in the plant fiber material and produce glucose. In the hydrolysis process, the cluster acid catalyst and a first amount of the plant fiber material that increases a viscosity of the cluster acid catalyst in a pseudo-molten state when added to the cluster acid catalyst in a pseudo-molten state are heated and mixed, and a second amount of the plant fiber material is then further added when the decrease in viscosity of the heated mixture occurs. | 2011-05-05 |
20110105745 | COMPOSITIONS AND METHODS OF MAKING A PHOTOACTIVE AGENT - An improved two stage reaction process for production of mono-L-aspartyl chlorin e | 2011-05-05 |
20110105746 | METHOD OF MAKING PORPHYRINS - A method of making a compound of Formula I: | 2011-05-05 |
20110105747 | QUINOLINE DERIVATIVE AND QUINAZOLINE DERIVATIVE INHIBITING SELF-PHOSPHORYLATION OF HEPATOCYTUS PROLIFERATOR RECEPTOR, AND MEDICINAL COMPOSITION CONTAINING THE SAME - An objective of the present invention is to provide compounds having potent antitumor activity. The compounds of the present invention are represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof: | 2011-05-05 |
20110105748 | Novel beta-phenyl-alpha-oxysubstituted propionic derivatives: process for its preparation and their use in the preparation of pharmaceutically important compounds - The present invention relates to novel propionic acid derivatives. More particularly, the present invention relates to beta-phenyl alpha-oxysubstituted propionic acids of the general formula (I). The present invention also relates to processes for the preparation of compounds of the formula (I) and their use in the preparation of compounds of formula (II). | 2011-05-05 |
20110105749 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 2011-05-05 |
20110105750 | Salts of a Pyrazino[2,3-h][3]Benzazepine Derivative - This invention provides novel dicarboxylic acid salt forms of varenicline, wherein the acid is selected from maleic acid, fumaric acid, adipic acid, galactaric acid and malic acid. This invention provides also a carboxylic acid salt form of varenicline, wherein the acid is S-2-pyrrolidinon-5-carboxylic acid. This invention also provides methods for making these salt forms. | 2011-05-05 |
20110105751 | CONVERSION OF TRYPTOPHAN INTO BETA-CARBOLINE DERIVATIVES - The invention belongs in the field of organic chemistry and relates to a new shortened Pictet-Spengler type reaction for preparing isomerically pure β-carboline compounds useful for the synthesis of tadalafil. | 2011-05-05 |
20110105752 | PROCESS FOR THE PREPARATION OF PIPERAZINYL AND DIAZEPANYL BENZAMIDE DERIVATIVES - The present invention is directed to a novel process for the preparation of piperazinyl and diazepanyl benzamide derivatives, useful for the treatment of disorders and conditions mediated by a histamine receptor, preferably the H3 receptor. | 2011-05-05 |
20110105753 | PROCESS FOR THE PREPARATION OF PYRAZINONE THROMBIN INHIBITOR AND ITS INTERMEDIATES - Improved process for the preparation of 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one-1-acetamide of formula (I) and its intermediates is provided. | 2011-05-05 |
20110105754 | NOVEL RHODAMINE DYES - There are described novel rhodamine color-forming compounds. The rhodamine color-forming compounds exhibit a first color when in a crystalline form and a second color, different from the first color, when in an amorphous form. | 2011-05-05 |
20110105755 | METHOD FOR EXTRACTING AND PURIFYING BISBENZYLISOQUINOLINES - A method for purifying extracted crude d-tetrandrine by dissolving the crude d-tetrandrine powder in ethanol, treating the solution with a decolorizing agent, filtering, reducing the filtered solution under heat and vacuum, cooling the solution, filtering it and drying the filtered cake to yield substantially pure d-tetrandrine. | 2011-05-05 |
20110105756 | Process for Preparing Quinoline-3-Carboxamide Derivatives - Disclosed herein is an improved, commercially viable and industrially advantageous process for the preparation of quinoline-3-carboxamide derivatives such as laquinimod, or a pharmaceutically acceptable salt thereof, in high yield and purity. | 2011-05-05 |
20110105757 | METHOD FOR PREPARATION OF MONTELUKAST ACID IN IONIC LIQUID MEDIUM - The present invention relates to a method for preparing Montelukast acid or its sodium salt by reacting a thiol compound with a Montelukast intermediate in the presence of a base in a medium comprising an ionic liquid compound. In accordance with the inventive method, highly pure Montelukast acid or its sodium salt, which is advantageously used as a raw material in the preparation of Montelukast, a leukotriene antagonist, can be easily prepared in a high yield. | 2011-05-05 |
20110105758 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED CYCLIC BETA-ARYL OR HETEROARYLCARBOCYCLIC ACIDS - The present invention relates to a process for the preparation of cis substituted cyclic β-aryl or heteroaryl carboxylic acid derivatives in high diastereo- and enantioselectivity by enantioselective hydrogenation in accordance with the following scheme | 2011-05-05 |
20110105759 | PROCESS FOR PRODUCING 1-BENZYL-4- [ (5,6-DIMETHOXY-1-INDANONE)-2-YLIDENE] METHYLPIPERIDINE - It is intended to provide a process for producing 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-ylidene]methylpiperidine represented by the structural formula (I): (I) which is useful as an intermediate material for a pharmaceutical or a solvate thereof in which impurity content is further reduced and operation is simple and suitable for industrial production by reacting 5,6-dimethoxy-1-indanone with 1-benzyl-4-formylpiperidine in a reaction solvent in the presence of a base and then gradually crystallizing a target substance in a reaction mixture in a high temperature region. | 2011-05-05 |
20110105760 | Method for Producing Aminobiphenylene - The present invention relates to a process for preparing substituted 2-aminobiphenyls and to a process for preparing (Het)arylamides of such 2-aminobiphenyls. | 2011-05-05 |
20110105761 | Salts Comprising Aryl-Alkyl-Substituted Imidazolium and Triazolium Cations and the Use Thereof - The present invention relates to salts comprising novel aryl-alkyl-substituted imidazolium and triazolium cations and arbitrary anions. The invention further relates to methods for the chemical conversion and separation of substances, comprising the salts according to the invention as solvents, solvent additives, or extraction means, and to the use of the salts according to the invention, for example as solvents or solvent additives in chemical reactions, as extracting agents for the separation of substances, or for storing hydrogen. According to the invention, the object is achieved by salts of the general formula (I), where X— is an anion, Y1 and Y2 are CH, or Y1 is CH and Y2 is N, or Y1 is N and Y2 is CH, n is a number from 1 up to an including 18, Q is selected from —CH3, —OH, —ORx, —S03H, —S03Rx, —COOH, —COORx, —CORx, NH2, —NHRx, —N(Rx)2, and —CH(Rx)2, Z is H or Rx, R1, R2, R3, R4 and R5 independently from each other are —H, -halogen, —N02, —NH2, —NHRx, —N(Rx)2, —Rx, —COORx or —ORx, where Rx is an optionally substituted and/or branched C1 to C18-alkyl group, excluding compounds of the general formula (I), where Y1 and Y2 are CH and R1, R2, R3, R4 and R5 are H, excluding compounds of the general formula (I), where Y1 and Y2 are CH, R1=R3=R5=CH3 is true, n=1, 2, 6 and Q=CH3 is true, excluding compounds of the general formula (I), where Y1 is CH and Y2 is N, R1, R2, R3, R4 and R5 are H, n=1 is true, and Q=CH3 is true, and excluding compounds of the general formula (I), where Y1 and Y2 are CH, R1, R2, R4, R5=H is true, R3=ORx is true, and Rx is a hydrocarbon having 3 or 12 carbon atoms. | 2011-05-05 |
20110105762 | TOTAL SYNTHESIS OF SALINOSPORAMIDE A AND ANALOGS THEREOF - The present invention relates to certain compounds and to methods for the preparation of certain compounds that can be used in the fields of chemistry and medicine. Specifically, described herein are methods for the preparation of various compounds and intermediates, and the compounds and intermediates themselves. More specifically, described herein are methods for synthesizing Salinosporamide A and its analogs from a compound of formula (V). | 2011-05-05 |
20110105763 | Process for Preparing Valsartan - An N-[(2′-(1-triphenyl methyl tetrazole-5-yl)biphenyl]-4-yl]methyl]-L-valine benzyl ester organic salt of formula (IVA) wherein A represents an organic carboxylic acid, a process for its preparation and its use in the synthesis of valsartan or salts thereof. | 2011-05-05 |
20110105764 | Copper-catalysed ligation of azides and acetylenes - A copper catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to provide 1,4-disubstituted 1,2,3-triazole triazoles. The process comprises contacting an organic azide and a terminal alkyne with a source of reactive Cu(I) ion for a time sufficient to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole. The source of reactive Cu(I) ion can be, for example, a Cu(I) salt or copper metal. The process is preferably carried out in a solvent, such as an aqueous alcohol. Optionally, the process can be performed in a solvent that comprises a ligand for Cu(I) and an amine. | 2011-05-05 |
20110105765 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS - 1,4-disubstituted-1,2,3-triazole UV absorbing monomers are disclosed. The UV absorbers are particularly suitable for use in intraocular lens materials. | 2011-05-05 |
20110105766 | Method for Producing Substituted Biphenyls - A process for preparing substituted biphenyls of the formula I | 2011-05-05 |
20110105767 | Manufacturing process for enantiomerically pure 8-Aryloctanoic acids as Aliskiren - The invention describes a novel technical process and novel intermediates useful for the manufacture of enantiomerically pure 8-aryloctanoic acids of the formula I which are pharmaceutically active compounds as rennin inhibitors. | 2011-05-05 |
20110105768 | Oligothiophene Derivatives - The present invention is related to oligothiophene derivatives of the formula I or II: wherein X═H or CH | 2011-05-05 |
20110105769 | Novel Substance FKI-3864 and Method for Preparation Thereof - This invention relates to substance FKI-3864 represented by the following formula [I] having an inhibitory activity on the synthesis of triacylglycerols and a method for preparing the same. The substance FKI-3864 can be prepared by a method comprising culturing a microorganism which belongs to the genus | 2011-05-05 |
20110105770 | ADSORPTION SEPARATION PROCESSES FOR IONIC LIQUID CATALYTIC PROCESSES - Presently disclosed are methods and apparatus for separation of reaction products from reaction mixtures in an ionic liquid catalysis process, particularly in conversion of biomass, cellulose, and sugars into chemical intermediates such as 5-hydroxymethylfurfural (HMF). In one embodiment an ion exclusion adsorption mechanism is used for the separation process. The process comprises (i) mixing the ionic liquid-containing reaction mixture with de-ionized water, (ii) flowing the water solution mixture into an adsorption column, (iii) eluting the column with a water- and/or alcohol-based fluid, and (iv) collecting separated fractions at different elution times. | 2011-05-05 |
20110105771 | PROCESS FOR THE PRODUCTION OF AN OLEFIN OXIDE, A 1,2-DIOL, A 1,2-DIOL ETHER, A 1,2-CARBONATE, OR AN ALKANOLAMINE - A process for the epoxidation of an olefin comprising contacting a reactor feed comprising an olefin, oxygen, and carbon dioxide, with a catalyst comprising a carrier and, deposited on the carrier, silver, a rhenium promoter, a first co-promoter, and a second co-promoter; wherein the carbon dioxide is present in the reactor feed in a quantity of at most 3 mole percent based on the total epoxidation reactor feed; the first co-promoter is selected from sulfur, phosphorus, boron, and mixtures thereof; and the second co-promoter is selected from tungsten, molybdenum, chromium, and mixtures thereof; a process for preparing a 1,2-diol, a 1,2-diol ether, a 1,2-carbonate, or an alkanolamine. | 2011-05-05 |
20110105772 | CRYSTALLINE FORMS OF TIGECYCLINE HYDROCHLORIDE - The present invention relates to crystalline forms A and B of Tigecycline hydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline forms A and B of Tigecycline hydrochloride as intermediates for the formulation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form A of Tigecycline hydrochloride in an effective amount and to the use of crystalline form A of Tigecycline hydrochloride as anti-infective medicament. | 2011-05-05 |
20110105773 | PRODUCTION METHOD OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOOD OR DRINK, FRAGRANCE OR COSMETIC, OR PHARMACEUTICAL COMPRISING THE SAME - A problem as an object of the invention is to provide a production method of spilanthol in a large scale without using expensive reagents. The present invention provides a production method of N-isobutyl-2,6,8-decatrienamide, wherein a column chromatography purification step is not required in all processes. | 2011-05-05 |
20110105774 | METHOD FOR SYNTHESISING 9-AMINONONANOIC ACID OR THE ESTERS THEREOF FROM NATURAL UNSATURATED FATTY ACIDS - The invention relates to a method for synthesizing 9-aminononanoic acid or the esters thereof from natural unsaturated fatty acids, comprising at least one step of metathesis of the natural fatty acid and an oxidation step by oxidative cleaving. Said synthetic method uses widely available renewable starting materials and hence economical. | 2011-05-05 |
20110105775 | METHOD OF CONVERTING FREE FATTY ACID (FFA) FROM OIL TO METHYL ESTER - The present invention provides a method of converting free fatty acid (FFA) from oil to methyl ester, the method includes the steps (a) esterifying the FFA using an acidic catalyst dissolved in an alcohol, (b) separating excess alcohol, solid acid catalyst, water, glycerol, soap and other non-lipid soluble impurities from oil obtained from step (a), (c) neutralizing the oil from step (b), (d) drying the oil from step (c) and (e) transesterifying the oil from step (d) using an alkaline catalyst and an alcohol. | 2011-05-05 |
20110105776 | METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL - A method of electrochemically preparing a crystalline, porous, metal-organic framework material comprising at least one at least bidentate organic compound coordinately bound to at least one metal ion, in a reaction medium comprising the at least one bidentate organic compound, wherein at least one metal ion is provided in the reaction medium by the oxidation of one anode comprising the corresponding metal. | 2011-05-05 |
20110105777 | SILYL SUBSTITUTED 1,4-DISILACYCLOHEXANE DERIVATIVES AND PREPARATION METHOD THEREOF - The present invention relates to novel 1,4-disilacyclohexane derivatives and a preparation method thereof. More particularly, the invention provides a method for preparing 1,4-disilacyclohexane derivatives with a hexagonal ring structure at high yield through double silylation of an organosilane compound and a vinyl silane compound having an unsaturated double bond using quaternary organophosphonium salts as a catalyst. According to the present invention, tris(silyl)ethanes having three silyl groups in one molecule can be prepared at the same time and the catalyst can be recovered after reaction. Thus, the method is economical and enables mass-production of 1,4-disilacyclohexane derivatives and tris(silyl)ethanes which are precursors of organic-inorganic hybrid materials. | 2011-05-05 |
20110105778 | Materials for Organic Electroluminescence Devices - The present invention relates to compounds containing a moiety of the formula (1) and to the use thereof in organic electroluminescent devices and to organic electroluminescent devices which comprise compounds of this type. | 2011-05-05 |
20110105779 | CROSSLINK AGENTS - Novel crosslink agents are described that provide for the copolymerization of at least one hydrophilic monomer with at least one lens monomer typically used to prepare materials for ophthalmic lenses. The new crosslink agents have a relatively high selectivity for the hydrophilic monomer and limited reactivity with the crosslink agent used to polymerize the lens monomer. | 2011-05-05 |
20110105780 | Method for obtaining polysulphide monoorganoxysilanes - The invention concerns the preparation of sulphur-containing organosilicic compounds of general formula (I) wherein, for example: R | 2011-05-05 |
20110105781 | Process for the Synthesis of Long-Chain Fatty Acids - This invention relates to processes for preparing long-chain fatty acids of Formula I: | 2011-05-05 |
20110105782 | Process for the preparation of carbamates of primary and secondary polyamines - A process is described for the preparation of carbamates of primary and/or secondary polyamines, which process comprises the steps of vaporising a primary and/or secondary polyamine and reacting said vaporised primary and/or secondary polyamine with gaseous carbon dioxide. In particular, the process relates to the production of the carbamates of hexamethylenediamine, 1,4-diaminocyclohexane and 3-aminomethyl-3,5,5-trimethylcyclohexylamine. | 2011-05-05 |
20110105783 | PROCESS FOR THE PREPARATION OF FESOTERODINE - A process for the preparation of (R)-2-(3-diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)-phenol isobutyrate (Fesoterodine), its (S)-enantiomer, and novel intermediates useful in thei synthesis. | 2011-05-05 |
20110105784 | Multi-staged catalyst systems and process for converting alkanes to alkenes and to their corresponding oxygenated products - Alkenes, unsaturated saturated carboxylic acids, saturated carboxylic acids and their higher analogues are prepared cumulatively from corresponding alkanes utilizing using a multi-staged catalyst system and a multi-stage process which comprises steam cracking of alkanes to corresponding alkenes at flame temperatures and at short contact times in combination with one or more oxidation catalysts for catalytically converting the corresponding alkenes to further corresponding oxygenated products using short contact time reactor conditions. | 2011-05-05 |
20110105785 | PROCESS FOR PREPARING ISOCYANATES - The invention relates to a process for preparing isocyanates by reacting the corresponding amines with phosgene in the gas phase, if appropriate in the presence of at least one inert medium, the phosgene being passed into a reactor ( | 2011-05-05 |
20110105786 | Creatinol o-phosphate and synthesis method thereof - A creatinol O-phosphate is formed by chemically reacting a creatinol sulfate of creatinol compound with sulfuric acid to form a protected creatinol sulfate as a transition state of the synthesis process of the creatinol O-phosphate, wherein the protected creatinol is further reacted with one of P | 2011-05-05 |
20110105787 | Process for Producing Alkyl Glyceryl Sulfonates - A process for preparing alkyl glyceryl sulfonate includes fractionally distilling an alkyl glyceryl epoxide mixture to afford alkyl glyceryl epoxide of formula IV: | 2011-05-05 |