15th week of 2012 patent applcation highlights part 41 |
Patent application number | Title | Published |
20120088906 | Isolation of Phosphoproteins, Glycoproteins and Fragments thereof - The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. Metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for several types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics. | 2012-04-12 |
20120088907 | OLIGOMERIC COMPOUNDS FOR THE MODULATION OF SURVIVIN EXPRESSION - Oligonucleotides directed against the survivin gene are provided for modulating the expression of survivin. The compositions comprise oligonucleotides, particularly antisense oligonucleotides, targeted to nucleic acids encoding the survivin. Methods of using these compounds for modulation of survivin expression and for the treatment of diseases associated with either overexpression of survivin, expression of mutated survivin or both are provided. Examples of diseases are cancer such as lung, breast, colon, prostate, pancreas, lung, liver, thyroid, kidney, brain, testes, stomach, intestine, bowel, spinal cord, sinuses, bladder, urinary tract or ovaries cancers. The oligonucleotides may be composed of deoxyribonucleosides or a nucleic acid analogue such as for example locked nucleic acid or a combination thereof. | 2012-04-12 |
20120088908 | Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof - Prodrugs based on gemcitabine structure shown in formula (I) as well as their synthetic method and application are disclosed in the present invention, wherein the definitions for the groups of a, b, c, d, E, Z and V are described in the specification. By modifying the N | 2012-04-12 |
20120088909 | Method for producing polysaccharide derivatives - Process for esterifying, etherifying or silylating polysaccharide or derivatives thereof by means of an esterifying reagent, etherifying reagent or silylating reagent in the presence of an ionic liquid, in which | 2012-04-12 |
20120088910 | COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER - [Problem] To provide a coloring matter which has a good hue, and is capable of forming an image high in fastness property under various use conditions and environmental conditions, and particularly suitable for an ink. | 2012-04-12 |
20120088911 | NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | 2012-04-12 |
20120088912 | INHIBITORS OF BRUTON'S TYROSINE KINASE - Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. | 2012-04-12 |
20120088913 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED-8-ALKOXY[1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-2-AMINES - 5-Substituted-8-alkoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amines are manufactured from 2-substituted-4-amino-5-methoxypyrimidines in a process that avoids hydrazine and cyanogen halide. | 2012-04-12 |
20120088914 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS - 4-amino-6-alkynyloxypyrimidine compounds shown by the formula (V) | 2012-04-12 |
20120088915 | STEREOSELECTIVE METHODS, CATALYSTS AND INTERMEDIATES FOR THE SYNTHESIS OF (-)-NUTLIN-3 AND RELATED COMPOUNDS - The present invention provides methods and intermediates are provided for the preparation of (−)-Nutlin-3. Methods and intermediates are also provided for the enantioselective addition of aryl nitromethanes to aldimines. Bis(amidine) catalysts for the use in these and other reactions are also provided. | 2012-04-12 |
20120088916 | OCTAHYDRO BIQUINOLINE COMPOUND - The present invention relates to an octahydro biquinoline compound. Provided is also a method of separating the octahydro biquinoline compound into enantiomers. The octahydro biquinoline compound is of the general formula (V): In formula (V) R | 2012-04-12 |
20120088917 | NEW QUINUCLIDINE DERIVATIVE USEFUL IN THE PREPARATION OF MEQUITAZINE - The invention relates to a 1-aza-bicyclo [2.2.2] oct-2-en-3-ylmethyl acetate of the formula (I), wherein said compound is useful as a synthesis intermediate for the production of mequitazine. | 2012-04-12 |
20120088918 | Continuous Method For Producing Esters Of Aromatic Carboxylic Acids - The invention relates to a continuous method for producing aromatic carboxylic acid esters by reacting at least one aromatic carboxylic acid of formula (I) Ar—COOH (I), wherein Ar represents an optionally substituted aryl group with 5 to 50 atoms, with at least one alcohol of formula (II) R | 2012-04-12 |
20120088919 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS - The invention relates to compounds having the formula: | 2012-04-12 |
20120088920 | CLATHRATE COMPOUND, CURING CATALYST, COMPOSITION FOR FORMING CURED RESIN, AND CURED RESIN - A curing catalyst (clathrate compound) for which the curing reaction is suppressed at low temperatures, allowing an improvement in the one-pot stability, but which can effectively cure a resin upon heat treatment. The clathrate compound includes at least an isophthalic acid compound represented by Formula (I), where R | 2012-04-12 |
20120088921 | COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND SEMICONDUCTOR DEVICE - A compound is represented by the following formula: | 2012-04-12 |
20120088922 | NOVEL 3.2.1-BICYCLO-OCTANE COMPOUNDS - The present invention relates to novel compounds and their use in fragrance compositions. Novel 3.2.1-bicyclo-octane compounds of the present invention are represented by formula: | 2012-04-12 |
20120088923 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND - Disclosed herein is a method for preparing a coumarin compound of formula (F), in which R | 2012-04-12 |
20120088924 | STEREOSELECTIVE SYNTHESIS OF BRIDGED METALLOCENE COMPLEXES - The present invention provides methods of making stereo-enriched ansa-metallocene compounds using an unchelated amine compound. Generally, these methods result in a rac:meso isomer selectivity of the stereo-enriched ansa-metallocene compound of greater than 4:1. | 2012-04-12 |
20120088925 | Novel Alpha-(N-Sulfonamido)Acetamide Compound as an Inhibitor of Beta Amyloid Peptide Production - The present invention provides a novel alpha-(N-sulfonamido)acetamide compound, its pharmaceutical composition, processes thereof and a method for the treatment of Alzheimer's disease and other conditions associated with β-amyloid peptide. | 2012-04-12 |
20120088926 | PROCESS FOR THE PREPARATION OF A IODINATING AGEN - The present invention describes a process for the synthesis of a iodinating agent, being said iodinating agent iodine chloride (ICI.) In particular, the present invention relates to a process for the electrochemical preparation of ICI, as a useful iodinating agent in the preparation of iodinated organic compounds for use as contrast agents or their precursors in the synthesis of the same. | 2012-04-12 |
20120088927 | Methods for the Formation of Hydrogels Using Thiosulfonate Compositions and Uses Thereof - The present invention provides both crosslinked polymer compositions capable of forming hydrogels upon exposure to an aqueous environment and thiosulfonate hydrogel-forming components. The thiosulfonate hydrogel-forming components of the invention are preferably multi-arm thiosulfonate polymer derivatives that form a crosslinked polymer composition when exposed to a base without requiring the presence of a second cross-linking reagent, redox catalyst, or radiation. Methods for forming hydrogel compositions, as well as methods for using the hydrogels, are also provided. | 2012-04-12 |
20120088928 | USE OF S- (3-AMINOPROPYL)THIOSULFURIC ACID OR METAL SALT THEREOF - Use of S-(3-aminopropyl)thiosulfuric acid and/or a metal salt thereof for improving the viscoelastic properties of a vulcanized rubber. | 2012-04-12 |
20120088929 | Production of a acetic acid comprising feeding at least one reactant to a recycle stream - This invention relates to processes for producing acetic acid from carbon monoxide and, in particular, to improved processes, wherein at least one reactant is fed upstream of a reactor recycle pump and/or to a pump-around loop. | 2012-04-12 |
20120088930 | METHODS FOR SALT PRODUCTION - The present invention provides methods to produce arginine bicarbonate more rapidly and efficiently than conventional methods. | 2012-04-12 |
20120088931 | METHOD FOR PRODUCING ALPHA,BETA-UNSATURATED CARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE AND METHOD FOR PRODUCING 3-ALKOXYCARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE - The invention is directed to a technique for effectively producing an amide compound suitable for use as a solvent or a detergent on a large scale and at low cost. | 2012-04-12 |
20120088932 | PROCESS FOR PRODUCING (METH) ACRYLIC ACID - A process for producing (meth)acrylic acid, comprising the step of repeating a crystallization operation “n” times (providing “n” is an integer 2 or more) to produce purified (meth)acrylic acid from crude (meth)acrylic acid, wherein a (meth)acrylic acid solution is crystallized and the crystallized (meth)acrylic acid is melted to obtain a (meth)acrylic acid melt in the crystallization operation; wherein a constant amount A | 2012-04-12 |
20120088933 | Tetramerization ligands - An ethylene oligomerization catalyst which contains a bridged diphosphine ligand having the formula (R | 2012-04-12 |
20120088934 | OLIGOMER FUNCTIONALIZED NANOTUBES AND COMPOSITES FORMED THEREWITH - Disclosed herein is a sequential functionalization methodology for the covalent modification of nanotubes with between one and four repeat units of a polymer. Covalent attachment of oligomer units to the surface of nanotubes results in oligomer units forming an organic sheath around the nanotubes, polymer-functionalized-nanotubes (P-NTs). P-NTs possess chemical functionality identical to that of the functionalizing polymer, and thus provide nanoscale scaffolds which may be readily dispersed within a monomer solution and participate in the polymerization reaction to form a polymer-nanotube/polymer composite. Formation of polymer in the presence of P-NTs leads to a uniform dispersion of nanotubes within the polymer matrix, in contrast to aggregated masses of nanotubes in the case of pristine-NTs. The covalent attachment of oligomeric units to the surface of nanotubes represents the formation of a functional nanoscale building block which can be readily dispersed and integrated within the polymer to form a novel composite material. | 2012-04-12 |
20120088935 | PROCESS FOR PREPARING KETONES, IN PARTICULAR MACROCYCLIC KETONES - Ketones of the formula II | 2012-04-12 |
20120088936 | METHOD FOR SYNTHESIZING COMPOUND AND CATALYST FOR SYNTHESIS REACTION - In Suzuki Cross-Couplings, a palladium-containing perovskite-type composite oxide represented by the following general formula (1) is used as a catalyst for synthesis reaction: | 2012-04-12 |
20120088937 | METHOD FOR PRODUCING CUMENE - One exemplary embodiment can be a method for processing polyisopropylbenzene for producing cumene. The method can include passing a transalkylation feed stream to a transalkylation zone, and passing a reaction product to a separation zone. Typically, the separation zone produces a stream including di-isopropylbenzene, tri-isopropylbenzene, and one or more heavy compounds. Moreover, the stream may include at least about 0.7%, by weight, of the one or more heavy compounds based on the weight of the di-isopropylbenzene, tri-isopropylbenzene, and the one or more heavy compounds in the stream, and at least a portion of the stream is recycled to the transalkylation zone. | 2012-04-12 |
20120088938 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL - Disclosed is a method for producing an optically active alcohol including reacting a titanium compound, an aromatic magnesium compound and a carbonyl compound in the presence of an optically active biphenol compound having a predetermined structure and an ether compound having a predetermined structure. | 2012-04-12 |
20120088939 | HYALURONIC ACID PRODUCTION PROMOTER AND MELANIN PRODUCTION INHIBITOR - Provided is a hyaluronic acid production promoter and a melanin synthesis inhibitor. The hyaluronic acid production promoter and the melanin synthesis inhibitor of the present invention each contain soybean saponin as an active ingredient. The soybean saponin is preferably soybean saponin aglycone. The soybean saponin aglycone preferably includes soyasapogenol A and/or soyasapogenol B. The hyaluronic acid production promoter and the melanin synthesis inhibitor of the present invention are each administered transdermally or orally. | 2012-04-12 |
20120088940 | REFLUX CONDENSER - Methods, apparatus, and processes are provided for a condenser including flowing a vapor stream including formaldehyde into a tube bundle in a vertical upflow reflux condenser, where a tube in the tube bundle has a length to outside diameter ratio of greater than about 170:1, flowing a cooling fluid on a shell-side of the vertical upflow reflux condenser to condense at least a portion of the vapor stream, where the condensed portion of the vapor stream forms a wetted tube internal surface area on each tube in the generally upright tube bundle; and maintaining the vapor stream velocity at a rate that provides a liquid residence time where formaldehyde condensed on the wetted internal surface area of each tube can react with water to form methylene glycol, removing at least sixty percent (60%) of formaldehyde from the vapor stream fed to the condenser. | 2012-04-12 |
20120088941 | POLYOL REFINING - The subject of the present invention is a method for refining of polyols, preferably glycerol, by means of monodispersed ion exchangers in a purification unit of ion exclusion process and a mixed bed. | 2012-04-12 |
20120088942 | Pyroglutamic Acid Esters With Improved Biodegradability - The invention relates to compounds of formula (1) in which A represents a C | 2012-04-12 |
20120088943 | METHOD AND APPARATUS FOR PREPARING FUEL COMPONENTS FROM CRUDE TALL OIL - A method for preparing fuel components from crude tall oil. Feedstock containing tall oil including unsaturated fatty acids is introduced to a catalytic hydrodeoxygenation to convert unsaturated fatty acids, rosin acids and sterols to fuel components. Crude tall oil is purified in a purification by washing the crude tall oil with washing liquid and separating the purified crude tall oil from the washing liquid. The purified crude tall oil is introduced directly to the catalytic hydrodeoxygenation as a purified crude tall oil feedstock. An additional feedstock may be supplied to the catalytic hydrodeoxygenation. | 2012-04-12 |
20120088944 | PROCESS FOR THE PREPARATION OF HYDROCARBONS - The invention provides a process for the preparation of hydrocarbons comprising the steps of:
| 2012-04-12 |
20120088945 | CO-PRODUCTION OF RENEWABLE DIESEL AND RENEWABLE GASOLINE - A process for co-production of renewable diesel fuel range hydrocarbons and gasoline fuel range hydrocarbons from biomass-derived oils and fatty materials (e.g. triglycerides, diglycerides, monoglycerides, and free fatty acids) and biomass-derived polyol (e.g. sorbitol, xylitol, trehalose, sucrose, and sugar alcohol), respectively, in a same refinery hydrotreater with or without co-feeding of diesel fuel range hydrocarbons. | 2012-04-12 |
20120088946 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND - Disclosed is a method for producing an unsaturated hydrocarbon compound wherein an α-olefin is dimerized by using a catalyst system composed of a metallocene compound (A) and an oxygen-containing organometallic compound modified with a halogen-containing compound (B). By this method, an unsaturated hydrocarbon compound having unsaturated double bonds in a high ratio, in particular the one having a terminal vinylidene group can be produced efficiently. | 2012-04-12 |
20120088947 | PROCESS FOR OXIDATIVE DEHYDROGENATION OF PARAFFINIC LOWER HYDROCARBONS - The present invention relates to a process for producing lower olefinic hydrocarbons by oxidative dehydrogenation of paraffinic lower hydrocarbons. More particularly the present invention provides a process for converting a feedstream comprising a paraffinic lower hydrocarbon and carbon dioxide to a product stream comprising an olefinic lower hydrocarbon and synthesis gas in the presence of the catalyst composition La—Mn/inert support, wherein said catalyst composition comprises 1-10 mass % lanthanum and 1-10 mass % manganese and optionally 0.3-3 mass % alkali metal. | 2012-04-12 |
20120088948 | Production of a high octane alkylate from ethylene and isobutene - A method of producing a high octane alkylate from ethylene and isobutane by reacting ethylene and isobutane under catalytic conversion conditions. The ethylene and isobutane are contacted with a first catalytic material comprising a dimerization catalyst (i.e, for dimerizing ethylene) and a second catalytic material comprising an alkylation catalyst. The first and second catalytic materials are separate and distinct from each other. A high octane alkylate is recovered as a result of reacting the ethylene and isobutane in the presence of the first and second catalytic materials. | 2012-04-12 |
20120088949 | Ion Exchange Regeneration and Nuclide Specific Selective Processes - A method of processing ion exchange resin radioactive waste, wherein the radioactive waste contains a plurality of fractions of radioactive waste based on density, which may include cation resin waste and anion resin waste, wherein at least one of the plurality of fractions comprises a total concentration of at least one radionuclide, including performing at least one of the following operations (i), (ii) or (iii): (i) separating the at least one of the plurality of fractions from the radioactive waste utilizing a moving freeboard; (ii) separating the radioactive waste into cation resin waste and anion resin waste; or (iii) removing at least a portion of the total concentration of the at least one radionuclide from: the radioactive waste; the at least one of the plurality of fractions separated by the moving freeboard; or at least one of the radioactive waste, the cation resin waste or the anion resin waste. | 2012-04-12 |
20120088950 | MICROWAVE PROCESSING OF FEEDSTOCK, SUCH AS EXFOLIATING VERMICULITE AND OTHER MINERALS, AND TREATING CONTAMINATED MATERIALS - Ways of applying microwaves to feedstock to be processed are disclosed. One embodiment relates to heating inter-layer water in vermiculite to expand the vermiculite. Another embodiment relates to heating water in oil-contaminated materials and waste products, such as drilling cuttings, contaminated soils and certain types of animal by-products, to drive out oil. In some embodiments a microwave tunnel applicator has the microwaves applied from beneath the feedstock. | 2012-04-12 |
20120088951 | PHARMACEUTICAL DRUG DISPOSAL KIT - A pharmaceutical drug disposal kit includes a container for receiving pharmaceutical drugs. Water is added to the container to create an aqueous solution with the pharmaceutical drugs, and a constituent in the container makes the solution a basic aqueous solution. A visual and/or taste deterrent is disposed in the container, and an adsorbent or absorbent is also disposed in the container to provide at least partial solidification of the solution. A binding agent is also disposed in the container to bind the ingredients of the pharmaceutical drug, the deterrent, and the adsorbent/absorbent, thereby changing the physical state of the pharmaceutical drugs into a substance that is undesirable to consume, and which enables safe disposal of the pharmaceutical drugs. | 2012-04-12 |
20120088952 | BRACHYTHERAPY DEVICE FOR FACILITATING ASYMMETRICAL IRRADIATION OF A BODY CAVITY - The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity. | 2012-04-12 |
20120088953 | Fractured Bone Treatment Methods And Fractured Bone Treatment Assemblies - Fractured bone treatment methods and fractured bone treatment assemblies are described. According to one aspect, a fractured bone treatment method includes generating an attractive magnetic force proximate to a fracture in a fractured bone and maintaining pieces of the fractured bone in proper anatomical positions with respect to one another using the attractive magnetic force. | 2012-04-12 |
20120088954 | Cardiac Pump - The pump is of an axial flow rotary pump, suitable for implantation into the human heart or vascular system, and comprises an elongate tubular casing ( | 2012-04-12 |
20120088955 | ARTERIAL DEVICE, SYSTEM AND METHOD - An arterial device, system and method are provided for use with a patient undergoing a cardiac procedure. The system is configured for enabling one or more arterial devices to be accommodated in the aorta of the patient in use of the system, and a perfusion lumen arrangement provides therethrough a target perfusion flow into the aorta having a target perfusion flow rate that is significantly greater than a nominal perfusion flow rate, by an excess perfusion flow rate. A suction lumen arrangement provides therethrough a suction flow out of the aorta at a suction flow rate. The target perfusion flow rate and the suction flow rate may be concurrently and selectively controlled to cause embolic debris that may be present in the aorta to be diverted to the suction inlet, while providing the nominal flow rate to the body circulation of the patient. | 2012-04-12 |
20120088956 | BONE CONDUCTION DEVICE HAVING AN INTEGRATED HOUSING AND VIBRATOR MASS - A bone conduction hearing aid device comprising a vibrator configured to vibrate in response to sound signals received by the device. The device further comprises a housing mass forming a housing for one or more operational components of the device, wherein the housing mass is attached to the vibrator so as to move in response to the vibration. The device also comprises a coupling configured to attach the device to a recipient so as to deliver the generated mechanical to the recipient's skull. | 2012-04-12 |
20120088957 | SUBCUTANEOUS PIEZOELECTRIC BONE CONDUCTION HEARING AID ACTUATOR AND SYSTEM - An implantable bone-conduction hearing actuator based on a piezoelectric element, such as a unimorph or bimorph cantilever bender, is described. Unlike other implantable bone conduction hearing actuators, the device is subcutaneous and once implanted is entirely invisible. The device excites bending in bone through a local bending moment rather than the application of a point force as with conventional bone-anchored hearing aids. | 2012-04-12 |
20120088958 | NON-FIBROUS BARRIER FOR ORGAN RETENTION - A method of packing organs of a subject, the method including accessing an interior cavity of the subject, repositioning the organs to provide a surgical space in the abdominal cavity, and positioning a non-fibrous body against the organs to provide a barrier between the organs and the surgical space. | 2012-04-12 |
20120088959 | ORGAN PACKING DEVICE HAVING TRANSFORMABLE SUPPORT MEMBERS - An elastomeric device for packing the organs of a subject. The device comprises a central portion and one or more flaps collectively manually positionable within the subject to retain the organs of the subject in an operational, displaced position and to provide a surgical operational space; and at least one transformable support member disposed in at least one of the central portion and the flaps configured to transform from a first substantially compliant configuration to a second substantially rigid configuration. | 2012-04-12 |
20120088960 | BOWEL PACKING DEVICE HAVING A TETHER - A kit for packing the bowels of a subject. The kit comprises an elastomeric bowel packing device manually positioned within the subject to retain the bowels of the subject in an operational displaced position and to provide a surgical operational space; and an elongate tether having a distal end coupled to the device via an attachment arrangement. | 2012-04-12 |
20120088961 | BOWEL PACKING DEVICE HAVING A SUPPORT STRUCTURE - An elastomeric device for packing the bowels of a subject comprising: a central portion and one or more flaps collectively manually positionable within the subject to retain the bowels of the subject in an operational, displaced position and to provide a surgical operational space; and a support structure disposed in at least one of the central portion and the flaps configured to provide rigidity to the device. | 2012-04-12 |
20120088962 | SELF-ADJUSTING GASTRIC BAND - Generally described herein are automatic, self-adjusting, gastric banding systems and improvements thereof, that are capable of automatically relaxing and contracting in response to a large bolus passing through the area of a patient's stomach constricted by a gastric band. Alternatively, and/or in addition in one or more embodiments, the gastric banding systems described herein may also help prevent pouch dilatation and/or erosion. The apparatus and systems described herein aid in facilitating obesity control and/or treating obesity-related diseases while generally being non-invasive once implanted. Furthermore, certain embodiments of the self-adjusting gastric banding systems disclosed herein are automatically adjustable without complicated fluid control mechanisms, flow rate limiting devices, and/or valves. The automatic adjustments may also be made in response to other changes in the patient's esophageal-gastric junction, for example, in response to size, shape, and or location changes. | 2012-04-12 |
20120088963 | ENDOSCOPE HOLDING APPARATUS - A distal arm that holds a rigid endoscope includes a multi-joint articulated arm including first to fourth distal arm portions sequentially connected from a base portion side, and these first to fourth distal arm portions are configured so as to move on a vertical plane with horizontal rotational shafts as supports. In addition, behaviors of the respective distal arm portions are linked by a linking mechanism so that the first distal arm portion and the third distal arm portion behave in parallel to each other, and the second distal arm portion and the fourth distal arm portion behave in parallel to each other. | 2012-04-12 |
20120088964 | Methods and devices for pericardial access - Methods and devices for pericardial access are described. One embodiment of a device includes a distal portion with a visualization element, along with a retractable access element. The distal portion is inserted into and navigates through the body to locate the pericardium with the aid of the visualization element. The access element is then extended and used to create an access site in the pericardium, again with the aid of the visualization element. The methods and devices may also be used to access other internal cavities, other soft tissues and organs, and the mediastinal space. | 2012-04-12 |
20120088965 | MAGNETICALLY MANIPULATABLE SURGICAL CAMERA WITH REMOVABLE ADHESION REMOVAL SYSTEM - A surgical or diagnostic camera system is disclosed that has a disposable cap-like device that is structured for removal of adhesions while under direct visualization with the camera. The adhesion removal device may have an electrode on the tip that can be activated to enhance separation of tissues and may be configured to securely snap on to the housing of the camera system. | 2012-04-12 |
20120088966 | Medical Nanobody - A particle-sized nanobody that can be inserted into at least one major physiological system of a mammal's body such as the blood stream or the gastro-intestinal track or other system. The nanobody of the present invention can remain in the system for a predetermined time to perform a predetermined task. nanobodies of the present invention can contain processors and memory and thus can be capable of performing tasks that require algorithmic or expert reasoning. The Nanobodies can also contain various sensors and can optionally have the ability to communicate with an external station or with each other. The Nanobodies can be designed to self-destruct either after a predetermined time or upon command from an external station. Once a nanobody has self-destructed, natural mechanisms of the body can remove the debris. | 2012-04-12 |
20120088967 | Methods and Devices for Placement of an Intra-Abdominal or Intra-Thoracic Appliance Through a Natural Body Orifice - Natural orifice transenteric surgical methods and devices for placing a band or other appliance around a hollow bodily organ such as the stomach. In one alternative embodiment, such a band is placed in order to reduce the inner volume of the stomach. | 2012-04-12 |
20120088968 | Methods and devices for visualization and access - Methods and devices for visualizing and accessing a region inside a body are described. One embodiment of a device includes a working catheter which slides along an open track in a visualization catheter. The visualization catheter is inserted into the body to locate a region of the body with the aid of the visualization element. The working catheter then slides along the track to reach the region, and a working element is inserted through the working catheter to access the region, again with the aid of the visualization element. The methods and devices may also be used to access a variety of internal cavities, soft tissues and organs, and the mediastinal space. | 2012-04-12 |
20120088969 | ENDOSCOPE APPARATUS - An endoscope apparatus according to the subject matter includes: an illumination device configured to emit light to an object; an imaging device configured to generate a color imaging signal; a normal image generation device configured to generate a normal image from the color imaging signal; a spectral image generation device configured to generate a spectral image corresponding to a preset optical narrow band from the imaging signal; a display device configured to display a main screen region and a sub-screen region having a size less than a size of the main screen region; a switching signal generation device configured to generate a switching signal; and a display control device configured to control the display device so as to selectively switch between a region for displaying the normal image and a region for displaying the spectral image based on the switching signal. | 2012-04-12 |
20120088970 | ENDOSCOPE SYSTEM - An endoscope system includes: an endoscope scope insertion portion having an insertion portion configured to be inserted inside a living organism; an extracorporeal device which is disposed outside the living organism; a first scope-side signal connecting portion that is provided on the endoscope scope insertion portion and has a first electrode; and a cylindrical first extracorporeal-side signal connecting portion that is provided on the extracorporeal device and has a second electrode, the first extracorporeal-side signal connecting portion configured to engage with the first scope-side signal connecting portion. In this endoscope system, when the first scope-side signal connecting portion is engaged with the first extracorporeal-side signal connecting portion, at least a portion of the first scope-side signal connecting portion is located within an inside-cylinder space of the first extracorporeal-side signal connecting portion, and the first electrode and the second electrode are electrostatically coupled together. | 2012-04-12 |
20120088971 | ROTICAM: An Orotracheal Guide with Camera - A camera system for surveillance of a patient's throat is disclosed. The camera system comprises a camera associated with an upper dental arch tray, and does not rest on the patient's tongue. The camera system can optionally include a delivery system for medication, display, and lower dental arch tray. The camera system may be configured as a guide insert in a Rapid Orotracheal Intubation Device. | 2012-04-12 |
20120088972 | Change-Out Handle System and Medical Instrument - A change-out handle system is provided for releasably coupling two elongated, axially relatively displaceable functional parts to a medical instrument unit. The change-out handle system includes a first and a second handle part disposed axially relatively displaceably, a first coupler for releasably axially rigidly immovably coupling a first of the two functional parts to the first handle part and a second coupler for releasably, axially rigidly immovably coupling the second of the two functional parts to the second handle part. The second handle part has a pass-through opening for passing at least the first of the two functional parts. The change-out handle system can be used, for example, for medical solids trapping instruments. | 2012-04-12 |
20120088973 | SWITCHING VALVE ASSEMBLY FOR ENDOSCOPE - A switching valve assembly for an endoscope includes a cylinder, a piston unit, a button device, a flow channel in the piston unit, and plural flow openings. The piston unit changes over plural flow lines between communication and interruption by changing a combination of the flow openings with the flow channel for communication. The switching valve assembly includes a cylinder cap device and a slide device of a cup shape. A ring projection of the button device is directed downwards. A cup plate portion of the slide device contacts the ring projection when the piston unit is slid down to a halfway position. Seal packing deforms resiliently to seal the ring projection and cup plate portion together in an air-tight manner. A vent hole is formed through the cup plate portion, surrounded by the seal packing, for connection with one of the plural flow lines to come open to atmosphere. | 2012-04-12 |
20120088974 | HYBRID APPARATUS FOR FLUID SUPPLY FOR ENDOSCOPIC IRRIGATION AND LENS CLEANING - A hybrid apparatus for delivery of fluid in connection with endoscopic irrigation and lens cleaning including a connector which is adaptable to a flexible or rigid container, a connector arranged at the end thereof and connected via a tubing supply to a fluid, air and or gas source and to an endoscope during a procedure. | 2012-04-12 |
20120088975 | SWITCHING VALVE ASSEMBLY FOR ENDOSCOPE - A switching valve assembly for an endoscope includes a cylinder, a piston unit, a button device, a flow channel in the piston unit, and plural flow openings. The piston unit changes over plural flow lines between communication and interruption by changing a combination of the flow openings with the flow channel for communication. The switching valve assembly includes a cylinder cap device and a slide device of a cup shape. An end ring keeps the slide device contained in the cylinder cap device. A first coil spring is disposed between the slide device and cylinder cap device, for biasing the slide device in an upward direction from the cylinder. A second coil spring is disposed between the button device and slide device, for biasing the button device in the upward direction with smaller force of bias than the first coil spring. The slide device includes an inner guide sleeve. | 2012-04-12 |
20120088976 | SYSTEM AND METHOD FOR SUCTION-ASSISTED OBJECT REMOVAL - System and method to remove a foreign object from a body cavity, the system including: a speculum that has a base configured to attach to an otoscope head; a hollow tapered section, having a wide end coupled to the base, and a narrow end that is open; and a hollow tube having a proximal end and an open distal end; the proximal end coupled to the narrow end of the hollow tapered section to form a hollow interior of the speculum. The system further includes a suction port coupled to a lateral side of the speculum, the suction port configured to provide access from outside the speculum to the hollow interior of the speculum; a suction pump configured to provide a variably controlled suction strength; and an interface to provide the variably controlled level of suction to the suction port. | 2012-04-12 |
20120088977 | STABILIZED ELONGATE IMPLANTABLE VASCULAR ACCESS DEVICE - A vascular access port is described that is elongate in form. A distal end is coupled to a tube which leads into a body lumen. A proximal end has a head thereon with a septum which can be repeatedly penetrated by a needle and reseal, for repeated administration of medications or other compositions through the port and into the body of the patient. A wing is attached to the body that has two positions including a streamlined first position for implantation and a wider second position for stabilization of the port after implantation. A stay is preferably also provided to abut the wing when in the second position to keep the wing in the second position when fully deployed. | 2012-04-12 |
20120088978 | LAPAROSCOPE POUCH - A laparoscope pouch includes: a main shaft which is therein formed with a hollow; a handle shaft which is inserted and slidably moved in the main shaft; an arm which is disposed in one side of the handle shaft; a handle which is disposed in the other side of the handle shaft and is rotated relative to the handle shaft; an extraction bag which has an opening with its upper side opened, the arm inserted in the extraction bag to hold the opening; a lead which connects the extraction bag and the handle and fixes a position of the extraction bag by providing a tension to the extraction bag by rotation of the handle; and a slider which is coupled and fixed to the main shaft when the handle shaft is moved relative to the main shaft. The extraction bag can be tightly inserted and maintained in the arm by rotating the handle even during an operation, and the lead can be adjusted to an operation situation even if the lead is not properly arranged during manufacture. | 2012-04-12 |
20120088979 | LATERAL ACCESS SYSTEM AND METHOD OF USE - A surgical access device including a frame, first and second supports, and first and second retractor blades releasably coupled with the first and second supports, respectively. The frame has first and second arms. The first support is releasably coupled with the first and second arms. The second support is slidably mounted on the first and second arms. The second support is movable between a first position with the retractor blades in close cooperative position and a spaced apart position with respect to the first support. The first and second retractor blades each have a distal end portion configured and adapted to engage a vertebral body. In one method of use, the retractor is inserted through an incision in first orientation with the blades in close approximation and rotated approximately 90°, before spreading the retractor blades to retract tissue. | 2012-04-12 |
20120088980 | MEIBOMIAN GLAND ILLUMINATING AND IMAGING - In an illustrative embodiment, an apparatus for imaging a portion of a mammalian eyelid has an eye contact lenspiece configured to direct the light through an eyelid from posterior to anterior surface to thereby trans-illuminate the eyelid, when the light source illuminates the contact lens. An imaging device receives an image of the eyelid as it is trans-illuminated. Other methods and apparatus are presented in various embodiments, hence this abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract. | 2012-04-12 |
20120088981 | Matching of Regions of Interest Across Multiple Views - Described herein is a framework for multi-view matching of regions of interest in images. According to one aspect, a processor receives first and second digitized images, as well as at least one CAD finding corresponding to a detected region of interest in the first image. The processor determines at least one candidate location in the second image that matches the CAD finding in the first image. The matching is performed based on local appearance features extracted for the CAD finding and the candidate location. In accordance with another aspect, the processor receives digitized training images representative of at least first and second views of one or more regions of interest. Feature selection is performed based on the training images to select a subset of relevant local appearance features to represent instances in the first and second views. A distance metric is then learned based on the subset of local appearance features. The distance metric may be used to perform matching of the regions of interest. | 2012-04-12 |
20120088982 | Monitoring Device With An Accelerometer, Method And System - A monitoring device ( | 2012-04-12 |
20120088983 | IMPLANTABLE MEDICAL DEVICE AND METHOD OF CONTROLLING THE SAME - An implantable medical device (IMD) is provided. The IMD includes a medical procedure performing unit configured to perform a medical procedure inside a body of a user, a code generating unit configured to detect a motion state of the user, and to generate a motion code that represents a user's intention based on the detected motion state, and a control unit configured to control the medical procedure of the medical procedure performing unit based on the generated motion code. | 2012-04-12 |
20120088984 | MEGNETIC ELECTRICAL CONNECTOR FOR PATIENT MONITORS - The present disclosure relates to an electrical connector for providing signal isolation between various components of a physiological monitoring system. In an embodiment, the electrical connector is placed between a sensor and associated monitoring system and includes a physical barrier and inductive components. | 2012-04-12 |
20120088985 | METHODS AND SYSTEMS FOR MEASURING AND COMMUNICATING PAIN AND DISTRESS LEVEL - Systems and methods are described for communicating the distress or pain experienced by an infant or a non-communicative patient. The systems and methods can provide an objective quantification of pain and/or distress in conjunction with, e.g., various distressing procedures commonly found in the newborn intensive care unit (NICU). The systems may include a processor in communication with a distress level input device and a display configured to provide a representation of a pain or distress score calculated in the processor. The processor may include executable code to translate data from the distress level input into the distress score. | 2012-04-12 |
20120088986 | Physiological Measuring System Comprising a Garment in the Form of a Sleeve or Glove and Sensing Apparatus Incorporated in the Garment - A measuring system for measuring electrocardiogram signals comprises a diagnostic garment with ECG electrodes that may assume the form of a sleeve or glove. A disposable version of the glove can be inflated. By using an inflatable glove, the contour of the body is automatically matched by the contour of the glove. Samples from the ECG electrodes positioned on a diagnostic garment are compensated so that the samples better approximate samples from ECG electrodes that are positioned at classical locations. Also, samples from ECG electrodes are compensated to reduce signal noise resulting from positioning the ECG electrodes on the diagnostic garment. | 2012-04-12 |
20120088987 | GENERAL-PURPOSE MEDICAL INSTRUMENTATION - A general-purpose, low-cost system provides comprehensive physiological data collection, with extensive data object oriented programmability and configurability for a variety of medical as well as other analog data collection applications. In a preferred embodiment, programmable input signal acquisition and processing circuits are used so that virtually any analog and/or medical signal can be digitized from a common point of contact to a plurality of sensors. A general-purpose data routing and encapsulation architecture supports input tagging and standardized routing through modem packet switch networks, including the Internet; from one of multiple points of origin or patients, to one or multiple points of data analysis for physician review. The preferred architecture further supports multiple-site data buffering for redundancy and reliability, and real-time data collection, routing, and viewing (or slower than real-time processes when communications infrastructure is slower than the data collection rate). Routing and viewing stations allow for the insertion of automated analysis routines to aid in data encoding, analysis, viewing, and diagnosis. | 2012-04-12 |
20120088988 | DETECTION DEVICE, RECOVERY METHOD THEREFOR AND MONITORING SYSTEM - A detection device is retained in the rumen of a cow by being orally administered to the cow, and detects the state of the inside of the rumen. The detection device wirelessly transmits measured values of the rumen pH as detection results. A monitoring unit (receiver and monitoring server) acquires information transmitted from the detection device, and monitors the state of the inside of the rumen. The detection device is configured to be recoverable orally from the rumen of the cow. The operating conditions of the detection device are recorded in the detection device ahead of time, and can be updated by means of a wireless signal transmitted from a setting unit to the detection device. | 2012-04-12 |
20120088989 | Management Method And System For Implementation, Execution, Data Collection, and Data Analysis of A Structured Collection Procedure Which Runs On A Collection Device - In one embodiment, a method of performing a structured collection protocol by utilizing a collection device comprising a processor may include collecting at least one sample using the collection device. The at least one sample can be associated with biomarker data. A classification can be associated with the at least one sample via the processor. The classification can be based upon an intended use of the at least one sample. Compliance with an adherence criteria for the at least one sample can be determined via the processor. When the at least one sample is not compliant with the adherence criteria, an adherence event can be associated with the at least one sample, and the processor can perform at least one additional task that is based upon the classification associated with the at least one sample. | 2012-04-12 |
20120088990 | MEDICAL SENSOR SYSTEM - A medical sensor system ( | 2012-04-12 |
20120088991 | ALGORITHM FOR PHOTONIC NEEDLE CONSOLE - Needles are widely used in interventional radiology. Each medical application requires a specific needle type. The same holds for the photonic needles which analysis depends on the type of application the clinician aims for. Therefore, it is relevant to have the X-ray machine recognize the type of needle that is being used and to load the required software for the tissue analysis. It is therefore proposed to have a data link established between the imaging modality used for the acquisition of the patient anatomy (X-ray, CT, MR or US) and the system that processes optical data from the needle, so that the information from this imaging modality can be used to guide the processing. In a preferred embodiment the selection is made by reading out the code present in the disposable needle when it is connected to the console. | 2012-04-12 |
20120088992 | METHOD FOR DETECTING AND DISCRIMINATING BREATHING PATTERNS FROM RESPIRATORY SIGNALS - A Cheyne-Stokes (CS) diagnosis system classifies periods of CS-like breathing by examining a signal indicative of a respiratory parameter. For example, nasal flow data is processed to classify it as unambiguously CS breathing or nearly so and to display the classification Processing may detect and display: apnoeas, hypopnoeas, flow-limitation and snore. The signal may be split into equal length epochs and event features are extracted. Statistics are applied to these primary feature(s) to produce secondary feature(s) representing the entire epoch. Each secondary feature is grouped with other feature(s) extracted from the entire epoch rather than from the epoch events. This final group of features is the epoch pattern. The epoch pattern is classified to produce a probability for possible event classes (e.g., Cheyne-Stokes breathing, OSA, etc.). The epoch is assigned to the class with the highest probability, which may both be reported as an indication of disease state. | 2012-04-12 |
20120088993 | ELECTROCHEMICAL SENSOR HAVING SYMMETRICALLY DISTRIBUTED ANALYTE SENSITIVE AREAS - The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid. | 2012-04-12 |
20120088994 | MEDICAL SENSOR SYSTEM FOR DETECTING A FEATURE IN A BODY - The invention relates to a medical sensor system ( | 2012-04-12 |
20120088995 | Analyte Monitoring Devices and Methods - Methods and devices for providing application specific integrated circuit architecture for a two electrode analyte sensor or a three electrode analyte sensor are provided. Systems and kits employing the same are also provided. | 2012-04-12 |
20120088996 | SYSTEM AND METHOD FOR DETERMINING THE POINT OF HYDRATION AND PROPER TIME TO APPLY POTENTIAL TO A GLUCOSE SENSOR - According to an embodiment of the invention, a method of determining hydration of a sensor having a plurality of electrodes is disclosed. In particular embodiments, the method couples a sensor electronics device to the sensor and measures the open circuit potential between at least two of the plurality of electrodes. Then, the open circuit potential measurement is compared to a predetermined value. In some embodiments, the plurality of electrodes includes a working electrode, a reference electrode, and a counter electrode. In still further embodiments, the open circuit potential between the working electrode and the reference electrode is measured. In other embodiments, the open circuit potential between the working electrode and the counter electrode is measured. In still other embodiments, the open circuit potential between the counter electrode and the reference electrode is measured. | 2012-04-12 |
20120088997 | Implantable biochip for managing trauma--induced hemorrhage - A biocompatible biosensor and transmitter device for temporary implantation prior to, during and following trauma-induced hemorrhaging detects the presence and level of at least one analyte and transmits detected data to a second, external device. Thus, a method for managing post-trauma patient outcomes includes providing such a biosensor and transmitter device, temporarily implanting the biocompatible biosensor and transmitter device intramuscularly in a trauma victim; and monitoring the presence and level of the at least one analyte detected by the biocompatible biosensor and transmitter device and transmitted to the external data receiving means. | 2012-04-12 |
20120088998 | Computer-Implemented System And Method For Evaluating Ambulatory Electrocardiographic Monitoring Of Cardiac Rhythm Disorders - A computer-implemented method for evaluating ambulatory electrocardiographic (ECG) monitoring of cardiac rhythm disorders is provided. A patient is registered online and medical records for the patient are assembled. An ambulatory ECG monitor that includes leadless integrated sensing electrodes independently suspended from a flexible housing, is registered to the patient. An electrocardiogram is retrieved from the recording circuitry. The electrocardiogram and the medical records are evaluated against diagnostic criteria. Upon making a finding when the diagnostic criteria is met, the patient is referred to a cardiac rhythm specialist online, which includes sending the cardiac rhythm abnormality finding. As a result, both physicians and patients enjoy an ease-of-use not found with conventional ambulatory ECG monitors. By bypassing determining whether a referral is needed and separately establishing the referral, patients can be treated more completely and more rapidly than through conventional patient referral, especially for serious illness, with less cost and less delay. | 2012-04-12 |
20120088999 | Ambulatory Electrocardiographic Monitor With Jumpered Sensing Electrode For Providing Ease Of Use In Women And Method Of Use - An ambulatory electrocardiographic (ECG) monitor with a jumpered sensing electrode and method of use for female and large-girthed patients is provided. Self-powered ECG sensing circuitry is fully enclosed in a housing with electrode receptacles on a bottom surface. A flexible and stretchable electrode mounting panel is provided with a layer of skin adhesive. A standoff pad is placed between the housing and the electrode mounting panel. Sensing electrodes are mounted on opposite ends of the mounting panel. Each sensing electrode includes an electrode pad facing the skin contacting surface and an oppositely-facing electrode plug. Each plug is removably and pivotably couplable into the receptacles. A jumper wire assembly includes a jumper plug electrically connected to a jumper receptacle. The jumper plug is removably and pivotably couplable into the receptacles and the jumper receptacle is removably and pivotably couplable into the plugs on the mounting panel opposite from the standoff pad. | 2012-04-12 |
20120089000 | Ambulatory Electrocardiographic Monitor For Providing Ease Of Use In Women And Method Of Use - A method for performing ambulatory electrocardiographic monitoring on an adult female is provided. An ambulatory ECG monitor, that includes a plurality of sensing electrodes coupled to self-powered sensing circuitry, is provisioned. A monitoring site is located on the surface of a patient's chest at midline and above the body of the sternum adjacent to the fourth and fifth intercostal spaces between the breasts in the upper portion of the intermammary cleft. The electrodes are aligned and placed along the midline. Interference from breast tissue with placement of the ambulatory monitor at the monitoring site is evaluated. The ambulatory ECG monitor is removably adhered to the monitoring site clear of any breast tissue interference for the duration of monitoring. ECG data is sensed through the sensing electrodes at the monitoring site and the sensed ECG data is recorded into the sensing circuitry. | 2012-04-12 |
20120089001 | Ambulatory Electrocardiographic Monitor And Method Of Use - A method for performing ambulatory electrocardiographic monitoring is provided. An ambulatory ECG monitor, that includes a plurality of sensing electrodes coupled to self-powered sensing circuitry, is provisioned. A monitoring site is located on the surface of a patient's chest at midline and above the body of the sternum adjacent to the fourth and fifth intercostal spaces. The electrodes are aligned and placed along the midline. The ambulatory ECG monitor is removably adhered to the monitoring site for the duration of monitoring. ECG data is sensed through the sensing electrodes at the monitoring site and the sensed ECG data is recorded into the sensing circuitry. | 2012-04-12 |
20120089002 | LOW COST-LOW PROFILE LEAD SET CONNECTOR - A patient worn medical monitoring device ( | 2012-04-12 |
20120089003 | 2D3D OVERLAY ON A CPR BASIS FOR ANEURYSM REPAIR - In a method for a fluoroscopy controlled insertion of a stent into a curved aorta of a patient for aneurysm repair, a 3D volume image is obtained of the patient's aorta at the aneurysm. By knowing a registration of the 3D volume image to a C-arm of an angiographic system and projection geometry of the angiography system, the 3D volume images are projected atomically correct to a 2D fluoroscopy image of the angiography system. For the 2D3D overlay, the 3D volume image is displayed as a curved planar reconstruction in which the 2D fluoroscopy image and the 3D volume image are warped around a curved center line of the patient's curved aorta or around a curved guide instrument center line to correct for the curvature of the aorta so that the previously curved aorta center line or curved center line of the guide instrument turns into a straight line. The 2D3D overlay is used to visualize the insertion of the stent. | 2012-04-12 |
20120089004 | METHOD FOR DATA OSCILLATOR DETECTION USING FRICTIONALLY DAMPED HARMONIC OSCILLATORS - A system and method for time-frequency analysis in which acquired signals are modeled as frictionally damped harmonic oscillators having a friction factor that is not a free parameter are provided. The friction factor is selected as a function of the frequency value of the associated oscillator, such that an increase in both temporal and spectral resolution are provided over existing time-frequency analysis methods. The friction factor is also selected to define a spectral band, within which the given oscillator can detect data oscillations. The properly selected friction factor thereby provides the analysis over a broad spectral range that can span many orders of magnitude. | 2012-04-12 |
20120089005 | Multi-Modal Medical Imaging and Type Detection - A multi-modal medical imaging and type detection have been described have been disclosed. By combining a broadband radio imaging system and one or more other modalities of image processing an enhanced image and/or tissue classification can be produced. | 2012-04-12 |