11th week of 2015 patent applcation highlights part 53 |
Patent application number | Title | Published |
20150073149 | Formation of N-Protected bis-3,6-(4-aminoalkyl)-2,5,diketopiperazine - The disclosed embodiments detail improved methods for the synthesis of diketopiperazines from amino acids. In particular improved methods for the cyclocondensation and purification of N-protected 3,6-(aminoalkyl)-2,5-diketopiperazines from N-protected amino acids. Disclosed embodiments describe methods for the synthesis of 3,6-bis-[N-protected aminoalkyl]-2,5-diketopiperazine comprising heating a mixture of an amino acid in the presence of a catalyst in an organic solvent. The catalyst is selected from the group comprising sulfuric acid, phosphoric acid, p-toluenesulfonic acid, 1-propylphosphonic acid cyclic anhydride, tributyl phosphate, phenyl phosphonic acid and phosphorous pentoxide among others. The solvent is selected from the group comprising: dimethylacetamide, N-methyl-2-pyrrolidone, diglyme, ethyl glyme, proglyme, ethyldiglyme, m-cresol, p-cresol, o-cresol, xylenes, ethylene glycol and phenol among others. | 2015-03-12 |
20150073150 | BLENDS OF AMINES WITH PIPERAZINE FOR CO2 CAPTURE - Compositions and methods related to the removal of acidic gas. In particular, the present disclosure relates to a composition and method for the removal of acidic gas from a gas mixture using a solvent comprising a blend of piperazine and at least one diamine or triamine. | 2015-03-12 |
20150073151 | SUPERCRITICAL FLUID EXTRACTION OF BIS-BENZYL ISOQUINOLINES - An improved process for obtaining at least one bis-benzyl isoquinoline alkaloid from botanical material involves contacting the botanical material with a supercritical fluid having as a major component one or more aliphatic hydrocarbon compounds, such as alkanes, alkenes, cyclic aliphatic hydrocarbons, or a combination of these compounds. | 2015-03-12 |
20150073152 | TRANSITION METAL COMPLEXES WITH CARBENE LIGANDS AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLEDS) - Use of transition metal complexes of the formula (I) in organic light-emitting diodes | 2015-03-12 |
20150073153 | PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS - Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): | 2015-03-12 |
20150073154 | Discrete PEG Based Dyes - Disclosed are discrete PEGylated dyes, that is, dyes, generally ones that are fluorescent, but could also include chemi-luminescent or electrochemiluminescent and related dye or dye precursors, that have discrete PEG constructs chemically attached in various configurations on the dye, and in the entire range of constructs, discrete PEG compounds (polyethylene glycol oligomers that are made synthetically according to methods disclosed in U.S. Pat. No. 7,888,536 and US Pub. No. 2013/0052130). The dyes are modified in a range of ways to control or optimize the properties of water solubility, non-specific binding (in vitro), biodistribution (in vivo), cell internalization (non-cell or cell based assays in vitro, and in vivo diagnostics and therapy), as well as aggregation. | 2015-03-12 |
20150073155 | MULTI-ARM POLYETHYLENE GLYCOL DERIVATIVE, INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING SAME - Provided is a multi-arm polyethylene glycol derivative having a narrow molecular weight distribution. A multi-arm polyethylene glycol derivative represented by the formula (1): | 2015-03-12 |
20150073156 | Production Method of a-Methylene Lactone - The present invention relates to a production method of α-methylene lactone which comprises the following steps: (A) a step of producing an enolate intermediate by making lactone react with alkyl formate under the presence of an alkoxide base; and (B) making the enolate intermediate react with paraformaldehyde. The production method of the present invention is capable of reducing the process time, improving yield, and minimizing the contamination of a reactor. | 2015-03-12 |
20150073157 | PROCESS FOR PREPARATION OF 3-((2S,5S)-4-METHYLENE-5-(3-OXOPROPYL)TETRAHYDROFURAN-2-YL)PROPANOL DERIVATIVES AND INTERMEDIATES USEFUL THEREOF - Discloses is a process for preparation of a compound of formula 7, or a derivative thereof, wherein PG | 2015-03-12 |
20150073158 | METHOD FOR PREPARING FUROFURAN LIGNAN COMPOUND - The present invention relates to a method for preparing a furofuran lignan compound, comprising a step of selecting and alkylating an epoxy alcohol compound and an optical isomer thereof. (+)-furofuran lignan and (−)-furofuran lignan, as well as an optical isomer thereof, can be selectively prepared by means of the method. | 2015-03-12 |
20150073159 | Solid State Forms Of Cabazitaxel And Processes For Preparation Thereof - The invention relates to solid state forms of Cabazitaxel, and processes for preparation, via novel synthetic intermediates, thereof, and formulations comprising one or more of the solid state forms of Cabazitaxel. The present invention further provides pharmaceutical compositions comprising one or more of the solid state forms of Cabazitaxel, and a method of treating hormone-refractory prostate cancer | 2015-03-12 |
20150073160 | PRODUCTION OF HEXAFLUOROPROPYLENE OXIDE - A process for the production of HFPO includes introducing a feedstock comprising HFP and molecular oxygen into a heated reaction zone of a reactor. The reaction zone is at a reaction temperature T | 2015-03-12 |
20150073161 | POMELO PEEL ESSENTIAL OIL EXTRACTION METHOD BY PEEL ICING AND BREAKING - A method of ice-crystal wall-breaking extraction of the pomelo peel essencial oil, including: first selecting a fresh pomelo, peeling off the outmost oil cell layer with a peeler, and collecting the cortex that is 1.5-2.5 mm thick; slowly freezing the pomelo peel oil cell layer at −15° C. to −30° C. to form ice crystal; breaking the pomelo peel ice crystal with a breaker; thawing the broken ice crystal, and then squeezing with a screw squeezer to obtain a squeezed mixed liquid; adding 3-4% by mass of the table salt to the squeezed mixed liquid, and standing to stratify at reduced pressure, thereby obtaining an oil-water mixture; distilling the mixed liquid at reduced pressure, and collecting the distillate to obtain an oil-water mixture that undergoes natural stratification; discarding the water layer, thereby obtaining the pomelo peel essential oil. | 2015-03-12 |
20150073162 | CONTINUOUS PROCESS FOR THE PRODUCTION OF DERIVATIVES OF SATURATED CARBOXYLIC ACIDS - Provided is a continuous process for the oxidative cleavage of derivatives of unsaturated carboxylic acids for the production of saturated carboxylic acids and their derivatives which comprises the steps of:
| 2015-03-12 |
20150073163 | Genetically Engineered Microorganisms that Metabolize Xylose - The invention provides methods of cultivating oil-bearing microbes using xylose as a fixed carbon source. Also provided are microorganisms that have been genetically engineered to metabolize xylose as a fixed carbon source allowing them to convert xylose into oils. Particular advantages of the processes provided herein include production of oils rather than alcohols through the microbial fermentation processes utilizing xylose. | 2015-03-12 |
20150073164 | METHOD FOR ADSORBING CARBON DIOXIDE ONTO POROUS METAL-ORGANIC FRAMEWORK MATERIALS, METHOD FOR COOLING POROUS METAL-ORGANIC FRAMEWORK MATERIALS, METHOD FOR OBTAINING ALDEHYDE USING POROUS METAL-ORGANIC FRAMEWORK MATERIALS, AND METHOD FOR WARMING POROUS METAL-ORGANIC FRAMEWORK MATERIALS - The present invention provides a method for adsorbing carbon dioxide onto porous metal-organic framework materials, a method for cooling porous metal-organic framework materials, a method for obtaining aldehyde using porous metal-organic framework materials and a method for warming porous metal-organic framework materials. In each method, porous metal-organic framework materials are used while an electric field or an electromagnetic field is applied to the porous metal-organic framework materials, or while a magnetic field or an electromagnetic field is applied to the porous metal-organic framework materials. If an electric field is applied, at least one organic compound included in the porous metal-organic framework materials is a polar compound. Instead, if a magnetic field is applied, at least one metal included in the porous metal-organic framework materials has an unpaired electron. | 2015-03-12 |
20150073165 | CATALYST COMPOUNDS - The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formula: (Formula (I)) where ring B is a conjugated ring system with one or more substituents. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions. | 2015-03-12 |
20150073166 | MODIFYING AGENT, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER USING MODIFYING AGENT, AND MODIFIED CONJUGATED DIENE POLYMER - Provided are a modifying agent obtained by subjecting a silicon-containing compound having a protected primary amino group and at least two hydrolyzable groups to complete condensation, a method of producing a modified conjugated diene-based polymer, a modified conjugated diene-based polymer obtained by the production method, a rubber composition using the polymer, and a pneumatic tire. The modified conjugated diene-based polymer has excellent low heat generating property and abrasion resistance, and the rubber composition is obtained by using the modified conjugated diene-based polymer and the pneumatic tire is obtained by using the rubber composition. | 2015-03-12 |
20150073167 | NANODOT AND METHOD FOR MANUFACTURING THE SAME - The present disclosure provides a method for manufacturing a nanodot, including: providing a hydrolysable silane, wherein the hydrolysable silane has one or more hydrolysable groups and one or more substituted or non-substituted hydrocarbon groups; and performing a one-step heat treatment to hydrolyze and condensate the hydrolysable silane to form a nanodot. The nanodot includes: a core, the core is selected from the group consisting of a semiconductor core or a metal core; and a self-assembled monolayer (SAM) including the substituted or non-substituted hydrocarbon groups, wherein the self-assembled monolayer is connected to the core by covalent bonds. | 2015-03-12 |
20150073168 | PROCESS FOR PREPARING AN INTERNAL OLEFIN SULFONATE - The invention relates to a process for preparing an internal olefin sulfonate, comprising sulfonating an internal olefin, having an average carbon number that is equal to or greater than 20, in a sulfonation reactor into sulfonated internal olefin followed by contacting sulfonated internal olefin with a base containing solution, wherein the sulfonation reactor is cooled with a cooling means having a temperature which is greater than 35° C. Further, the invention relates to an internal olefin sulfonate obtainable by said process, and to use of internal olefin sulfonates obtainable or obtained by said process as a surfactant, suitably as a surfactant in chemical Enhanced Oil Recovery. | 2015-03-12 |
20150073169 | PURIFICATION PROCESS - A process for reducing the level of contaminant metals in ligands used in the preparation of catalysts is disclosed. | 2015-03-12 |
20150073170 | KINETIC RESOLUTION - Whilst methodologies for the Kinetic Resolution of alcohols are well established, no analogous direct methods exist for the highly selective, direct catalytic Kinetic Resolution of thiols (i.e., R—SH). The present invention relates to a method for resolving stereoisomeric mixtures of thiols. In particular, the present invention relates to purely organocatalytic mediated resolution of enantiomeric mixtures of thiols without the need for enzymes. Also disclosed are some novel catalysts. Such catalysts may comprise a cinchona alkaloid-derived moiety. | 2015-03-12 |
20150073171 | STABILIZED (METH)ACRYLIC MONOMERS - The present invention relates to the stabilization of (meth)acrylic monomers against premature polymerization during synthesis, storage and transport. The term “(meth)acrylic monomers” is understood to mean derivatives both of methacrylic acid and of acrylic acid. | 2015-03-12 |
20150073172 | SYNTHESIS OF DIAMIDO GELLANTS BY USING DANE SALTS OF AMINO ACIDS - The invention relates to a method for the synthesis of a compound according to formula I comprising the following steps: a) reacting a Dane salt according to formula II and a Dane salt according to formula III with a coupling reagent; b) adding a diamine according to formula IV to the reaction mixture; and c) adding an acid to the reaction mixture to adjust the pH value of the reaction to <7; wherein L represents a C | 2015-03-12 |
20150073173 | LYSINE-GLUTAMIC ACID DIPEPTIDE DERIVATIVES - The invention relates to compounds of the formula | 2015-03-12 |
20150073174 | DEVICE USEFUL FOR HYDROGENATION REACTIONS (I) - The present invention relates to a device for treatment of material transported through the device comprising at least one porous element consisting of specific solid metallic structure which allows cross-flow of the material through the porous element and wherein the porous element is coated by a non-acidic metal oxide which is impregnated by palladium (Pd). | 2015-03-12 |
20150073175 | Process for the Preparation of Polyoxyalkylene Aminophosphonic Dispersing Agents R1-O-(CH2-CH2-O)n-CH2-CH2-N(R2)-R3-NR4R5 (I) - Disclosed is a process for the preparation of compounds of formula (I) wherein R1 is C1-C4 alkoxy; R2 is hydrogen or a group of formula —CH | 2015-03-12 |
20150073176 | LINEAR ALKYLBENZENES FROM NATURAL OILS AND METHODS OF PRODUCING - A linear alkylbenzene product and a linear alkylbenzene sulfonate product from a natural oil are provided. The linear alkylbenzene product comprises alkylbenzenes having the formula C | 2015-03-12 |
20150073177 | METHOD FOR INHIBITING TRYPANOSOMA CRUZI - Methods are provided to inhibit proliferation of | 2015-03-12 |
20150073178 | 4-(3-BENZYLOXYPHENYLTHIO)-2-CHLORO-1-(3-NITROPROPYL)BENZENE CRYSTAL - [Problem] For example, 4-(3-benzyloxyphenylthio)-2-chloro-1-(3-nitropropyl)benzene (compound 1) is used as an intermediate for producing a 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl]-1,3-propanediol hydrochloride which has excellent immunosuppressive activity. This compound 1 is traditionally obtained only as an oil and thus handling and refining were difficult. | 2015-03-12 |
20150073179 | Process for preparing cyclohexanol and cyclohexanone by cyclohexane oxidation - A process for preparing cyclohexanol and cyclohexanone by cyclohexane oxidation, includes steps of: firstly processing uncatalyzed oxidation on cyclohexane by molecular oxygen, in such a manner that an oxidized mixture with cyclohexyl hydrogen peroxide serving as a primary product is generated; then decomposing the cyclohexyl hydrogen peroxide to produce cyclohexanol and cyclohexanone; and then distilling to obtain a cyclohexanol product and a cyclohexanone product, wherein the step decomposing the cyclohexyl hydrogen peroxide utilizes a three-step decomposition process including steps of: (1) performing the homogeneous catalytic decomposition by utilizing the bis(tert-butyl)chromate as a catalyst; (2) performing the heterogeneous catalytic decomposition of the sodium hydroxide alkaline aqueous solution under low alkalinity; and (3) performing the heterogeneous catalytic decomposition of the sodium hydroxide alkaline aqueous solution under high alkalinity. | 2015-03-12 |
20150073180 | METHOD FOR CONTINUOUS PRODUCTION OF NITROBENZENE - The invention relates to a method for producing nitrobenzene, in which crude nitrobenzene is first produced by nitrating benzene and said crude nitrobenzene is then washed in succession in at least one acid wash, in at least one alkaline wash and in at least one neutral wash, at least one additional wash with an aqueous solution of a potassium salt being interposed between the last alkaline wash and the first neutral wash. | 2015-03-12 |
20150073181 | PROCESSES FOR PYROLYSIS VAPOR UPGRADING - This disclosure relates to the fast pyrolysis of organic matter. More specifically, it relates to the catalytic modification of vapors created during the fast pyrolysis of organic matter to create transportation fuel or a transportation fuel component. At least a first portion of pyrolysis vapors is catalytically stabilized or converted, then combined with a portion of raw, unconverted bio-derived pyrolysis vapors at a temperature and pressure sufficient for molecules of the combined vapors to react and produce hydrocarbons of increased molecular weight that are suitable for use as a hydrocarbon transportation fuel or component thereof. | 2015-03-12 |
20150073182 | PRODUCTION OF OLEFINS FROM A METHANE CONVERSION PROCESS - Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes the further conversion of the acetylene to a hydrocarbon stream comprising C6 to C12 olefins. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is treated to convert acetylene to another hydrocarbon, and in particular olefins. The method according to certain aspects includes controlling the level of contaminants in the hydrocarbon stream. | 2015-03-12 |
20150073183 | PRODUCTION OF OLEFINS FROM A METHANE CONVERSION PROCESS - Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes the further conversion of the acetylene to a hydrocarbon stream having propylene. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is treated to convert acetylene to another hydrocarbon, and in particular olefins. The method according to certain aspects includes controlling the level of contaminants in the hydrocarbon stream. | 2015-03-12 |
20150073184 | Controllability Oxidative Dehydrogenation Process for Producing Butadiene - Butadiene is made from a butene rich feed, passing a superheated butene rich feed including superheated steam and oxygen at a temperature of at least about 343° C. (650° F.) over a catalyst bed having a depth of over about 69 cm (27 inches) of granules of ferritic oxidative dehydrogenation catalyst. Inlet conditions being controlled such that the oxidative dehydrogenation reactions initially occur in the lower most layers of catalyst. Process control includes monitoring the temperature throughout the bed and increasing the inlet temperature in response to a drop in the temperature in the active layer, when the active layer of oxidative dehydrogenation catalyst begins to become deactivated so that the reaction zone moves upwardly in the oxidative dehydrogenation bed. | 2015-03-12 |
20150073185 | Novel Catalyst Complex and Use Thereof in Alkane Oligomerization - Provided is a Group 9 novel metal catalyst complex further comprising a ketone-containing cocatalyst. The metal catalyst complex is useful in generating olefins from alkanes with great efficiency. In one embodiment, provided is an iridium catalyst complex useful in the dehydrogenation of alkanes comprising a ketone-containing cocatalyst and iridium complexed with a tridentate ligand. Also provided is a novel dehydrogenation method which utilizes the catalyst composition. In other embodiments, a novel process for preparing oligomers from alkanes utilizing the catalyst composition is provided. | 2015-03-12 |
20150073186 | SPLIT FEED REACTOR BED IN HYDROTREATER DEVICE - A hydrotreater reactor device includes a reactor chamber including a first bed and a second bed. A first input is disposed to provide a hydrocarbon stream to the first bed and a second input is disposed to bypass the first bed and provide a hydrocarbon stream to the second bed. A differential temperature controller measures a temperature difference across the first bed. A control valve at the second input adjusts an amount of the hydrocarbon stream admitted through the second input based on the measured temperature difference. A charge heater provides a hydrocarbon stream as an output through a split output line having a first branch connected to the first input and in fluid communication with the first bed, and a second branch connected to the second input and in fluid communication with the second bed. A restrictor downstream of the split controls a pressure drop at the first input. | 2015-03-12 |
20150073187 | TOLUENE METHYLATION WITH TRANSALKYLATION OF HEAVY AROMATICS - A method of producing a purified mixed xylene comprising: introducing toluene and methanol to an alkylation reactor ( | 2015-03-12 |
20150073188 | PROCESSES FOR PRODUCING SYNTHETIC HYDROCARBONS FROM COAL, BIOMASS, AND NATURAL GAS - Methods of optimal refinery design utilizing a thermochemical based superstructure are provided. Methods of producing liquid fuels utilizing a refinery selected from a thermochemical based superstructure are provided. Thermochemical based superstructures are provided. Refineries are provided. | 2015-03-12 |
20150073189 | HIGH TEMPERATURE CCR PROCESS WITH INTEGRATED REACTOR BYPASSES - A process is presented for increasing the aromatics content in a reformate process stream. The process modifies existing processes to change the operation without changing the reactors or heating units. The process includes bypasses to utilize heating capacity of upstream heating units, and passes the excess capacity of the upstream heating units to downstream process streams. | 2015-03-12 |
20150073190 | Methods of Regenerating Aromatization Catalysts - Methods for treating or rejuvenating a spent catalyst are disclosed. Such methods can employ a step of halogenating the spent catalyst, followed by decoking the halogenated spent catalyst. The halogenation step can utilize fluorine and chlorine together, or fluorine and chlorine can be applied sequentially. | 2015-03-12 |
20150073191 | PROCESS FOR THE PREPARATION OF HYDROGENATED HYDROCARBON COMPOUNDS - A process for the dehydrogenation of a paraffinic hydrocarbon compound, such as an alkane or alkylaromatic hydrocarbon compound to produce an unsaturated hydrocarbon compound, such as an olefin or vinyl aromatic compound or mixture thereof, in which a dehydrogenation catalyst contacts gaseous reactant hydrocarbons in a reactor at dehydrogenation conditions. | 2015-03-12 |
20150073192 | CATALYSTS FOR PETROCHEMICAL CATALYSIS - Metal oxide catalysts comprising various dopants are provided. The catalysts are useful as heterogenous catalysts in a variety of catalytic reactions, for example, the oxidative coupling of methane to C2 hydrocarbons such as ethane and ethylene. Related methods for use and manufacture of the same are also disclosed. | 2015-03-12 |
20150073193 | Process for Nitrile Removal from Hydrocarbon Feeds - A process is described, such process comprising i) contacting a hydrocarbon feed with a heterogeneous catalyst under conditions suitable to hydrolyze nitriles present in the feed to form a nitrile hydrolysis product comprising ammonia, carboxylic acid and carboxylate salts or a mixture thereof; and ii) removing the nitrile hydrolysis product from the feed. In an embodiment, the hydrocarbon feed comprises olefins and is intended for use in an olefin oligomerization process. | 2015-03-12 |
20150073194 | Hydrocarbon Gas Processing - A process and an apparatus are disclosed for a compact processing assembly to improve the recovery of C | 2015-03-12 |
20150073195 | Hydrocarbon Processing - A process and an apparatus are disclosed for a compact processing assembly to fractionate lighter components from mixed hydrocarbon streams. The hydrocarbon stream is supplied to the processing assembly between an absorbing means and a mass transfer means. A distillation vapor stream is collected from the upper region of the absorbing means and cooled in a first heat and mass transfer means inside the processing assembly to partially condense it, forming a volatile stream and a condensed stream. The condensed stream is supplied to the absorbing means as its top feed. A distillation liquid stream is collected from the lower region of the mass transfer means and heated in a second heat and mass transfer means inside the processing assembly to strip out its volatile components, forming a relatively less volatile stream and a vaporized stream. The vaporized stream is supplied to the mass transfer means as its bottom feed. | 2015-03-12 |
20150073196 | Hydrocarbon Gas Processing - A process and an apparatus are disclosed for a compact processing assembly to remove C | 2015-03-12 |
20150073197 | Oxygenates-Free C8-C12 Aromatic Hydrocarbon Stream and a Process for Preparing the Same - The present disclosure provides a process for separating oxygenates present in an aromatic hydrocarbon stream to obtain an oxygenates-free aromatic hydrocarbon stream. The process involves selectively removing oxygenates from the aromatic hydrocarbon stream by passing said stream through at least one zeolite based adsorbing material. | 2015-03-12 |
20150073198 | Method of Chemical Decontamination for Carbon Steel Member of Nuclear Power Plant - A circulation pipe of a chemical decontamination apparatus including a malonic acid injection apparatus and an oxalic acid injection apparatus is connected to a purification system pipe, which is made of carbon steel, of a boiling water nuclear power plant. A malonic acid aqueous solution is injected from the malonic acid injection apparatus into the circulation pipe. An oxalic acid aqueous solution is injected from the oxalic acid injection apparatus into the circulation pipe. A reduction decontaminating solution including a malonic acid of 5200 ppm and an oxalic acid within a range of 50 to 400 ppm is supplied into the purification system pipe through the circulation pipe. Reduction decontamination for an inner surface of the purification system pipe is executed. After the reduction decontamination for the purification system pipe finishes, the malonic acid and oxalic acid included in the solution are decomposed and furthermore, the solution is purified. | 2015-03-12 |
20150073199 | HIGH-FREQUENCY CONTROL DEVICE FOR ACCELERATOR AND PARTICLE BEAM THERAPY SYSTEM - A hard disk drive memory which stores pattern data of a high-frequency to be applied for each combination of energy and intensity of the generated particle beam and a local memory, which reads a plurality of pattern data of a high-frequency for each patient together with a sequential order of changing energy and intensity from the hard disk drive memory and stores data in order to perform a scanning irradiation method in which a layered particle beam irradiation region in a depth direction of an affected part of the patient is formed sequentially by changing energy and intensity of the particle beam sequentially to irradiate an affected part of a patient which is an irradiation subject with the particle beam, and which reads out data faster than the hard disk drive memory are provided. | 2015-03-12 |
20150073200 | HADRON TREATMENT PLANNING WITH ADEQUATE BIOLOGICAL WEIGHTING - Treatment planning methods are provided that determine the variability of relative biological effectiveness (RBE) along a beam line and calculate, among other things, what intensity of hadron beam such as a proton or a carbon ion beam should be applied to achieve a desired biological dose at treatment site of a patient afflicted with a medical condition. Typically, three or four RBE values at three or four corresponding spacially-dispersed intervals along the beam line are calculated. In one embodiment, two RBE values for the spread-out Bragg peak (SOBP) region of the treatment site; one for the proximal section and one for the declining distal section is calculated. A third and different RBE value may be determined for the distal edge region of the SOBP. A fourth value may also be calculated for a pre-SOBP region. | 2015-03-12 |
20150073201 | APPLICABLE DEVICE FOR HEALING INJURIES WITH MAGNETIC FIELDS - A medical device includes a substrate, a magnetic field emitter disposed on a side of the substrate, and an adhesive on the side of the substrate opposite the emitter. | 2015-03-12 |
20150073202 | GUIDABLE INTRAVASCULAR BLOOD PUMP AND RELATED METHODS - An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient. | 2015-03-12 |
20150073203 | HEART FAILURE SYSTEMS AND METHODS - Embodiments of the disclosure include medical device systems and related methods. In an embodiment, the disclosure includes a medical device system. The medical device system can include a cardiac device. The cardiac device can include a processor, a memory, a communications circuit, and one or more sensors. The cardiac device can be configured to engage a sensor mode specific for patients receiving or having implanted ventricular assist devices. The cardiac device can be configured to process data as specified by the sensor mode specific for patients receiving or having implanted ventricular assist devices. In an embodiment, the disclosure includes a method for monitoring heart failure patients. In an embodiment, the disclosure includes a method of controlling devices for heart failure patients. Other embodiments are also included herein. | 2015-03-12 |
20150073204 | INCUBATOR'S CANOPY WITH SENSOR DEPENDENT VARIABLY TRANSPARENT WALLS AND METHODS FOR DIMMING LIGHTS THEREOF - An incubator with a canopy that selectively controls an amount of light that is transmitted into it. The incubator includes: at least one sensor configured to detect light transmitted into the incubator's capacity and to further convert the transmitted light into electrical current. The incubator also includes a canopy characterized by at least one portion, the portion comprises one or more smart incubator's glass (SIG); where the SIG is adapted to at least partially reduce or increase the light transparency via the portion in accordance with the sensor's electrical current. | 2015-03-12 |
20150073205 | Magnet Arrangement for Bone Conduction Hearing Implant - An implantable magnet arrangement is described for a hearing implant in a recipient patient. A pair of implant magnets are fixable in a common plane beneath the skin of the patient to underlying skull bone. At least one of the magnets is adapted to transform a magnetic drive signal from an external signal drive coil into a corresponding mechanical stimulation signal for delivery by bone conduction of the skull bone as an audio signal to the cochlea. Each implant magnet includes a pair of internal magnets lying in parallel planes which meet along a common junction with repelling like magnetic polarities facing towards each other. | 2015-03-12 |
20150073206 | PUNCTURE DEVICE AND PUNCTURE APPARATUS - A puncture device, a puncture apparatus, and a method are disclosed, the puncture apparatus including a puncture device for puncturing a biological tissue, a urethral-insertion member, a vaginal insertion member, and a supporting member which supports the urethral-insertion member, vaginal insertion member and a puncture member of the puncture device. The puncture device includes a puncture needle for puncturing a biological tissue, a shaft portion and a connection portion for connecting the puncture needle and the shaft portion to each other, and an implant assembly positioned at a distal end of the puncture needle and having a needle tip portion for puncturing a biological tissue and a biological tissue supporting implant. The puncture needle has a form of a pipe and has a tubular portion. The biological tissue supporting implant is accommodated in the hollow portion. | 2015-03-12 |
20150073207 | SINGLE-PASS ENDOSCOPIC VESSEL HARVESTING - An endoscopic harvesting device removes a vessel from a body. The vessel has an anterior side closest to the skin. A sheath extends in a longitudinal direction with a dissector tip for advancing along the vessel substantially along the anterior side to create a flanking tunnel spaced away from the vessel. A ring-shaped blade is mounted to the sheath and is disposed in a plane substantially perpendicular to the longitudinal direction and proximal of the dissector tip. The blade forms a lateral loop to encircle the vessel from the flanking tunnel and to make a vasiform cut including a pedicle around the vessel as the sheath advances. | 2015-03-12 |
20150073209 | STEREOSCOPIC ENDOSCOPE DEVICE - Provided is a stereoscopic endoscope device including a single objective lens that collects light from a subject and forms an image of the light; a light splitting section that splits the light collected by the objective lens; image-capturing devices that capture optical images of the subject at imaging positions of the split beams of the light; focal-position adjusting sections that give optical path lengths different from each other to the split beams of the light; a calculation section that calculates an object distance between each point on the subject and the objective lens from 2D images acquired by the image-capturing devices; and a parallax-image generating section that generates a plurality of viewpoint-images of the subject when observed from a plurality of viewpoints, by using the calculated object distance. | 2015-03-12 |
20150073210 | IMAGING SYSTEM, METHOD AND DISTAL ATTACHMENT FOR MULTIDIRECTIONAL FIELD OF VIEW ENDOSCOPY - An exemplary apparatus for imaging at least one anatomical structure can be provided. For example, the apparatus can include an endoscopic first arrangement, a radiation source second arrangement which provides at least one electro-magnetic radiation, and a third arrangement attached to at least one portion of the endoscopic arrangement. The third arrangement can contain an optical arrangement which, upon impact by the at least one electro-magnetic radiation and based thereon, may transmit a first radiation and reflects a second radiation. The first radiation can impact at least one first portion of the anatomical structure(s), and the second radiation can impact at least one second portion of the anatomical structure(s). The first and second portions can be at least partially different from one another. Further, the first and second radiations can have characteristics which are different from one another. | 2015-03-12 |
20150073211 | MICROWAVE ABLATION CATHETER, HANDLE, AND SYSTEM - A support system including a rail, a lower support, and an instrument support. The lower support is configured to receive a portion of a bronchoscope and to selectively fix the bronchoscope relative to the rail. The instrument support is slidably disposed on the rail and is selectively lockable to the rail. The instrument support is configured to releasably couple to a surgical instrument inserted through the bronchoscope to fix the position of a portion of the surgical instrument relative to the bronchoscope. | 2015-03-12 |
20150073212 | Endoscope Apparatus - An endoscope apparatus with which the inside of an inspection object can be observed in detail is provided. In addition, the structure of the endoscope apparatus is simplified. The endoscope apparatus includes a tubular insertion portion having an end portion, and the end portion is provided with a light-emitting device and an optical device. The optical device is provided on an end surface in the end portion, and the light-emitting device is provided along a side surface of the end portion. | 2015-03-12 |
20150073213 | SYSTEM AND METHOD FOR CONTROLLING POWER CONSUMPTION OF AN IN VIVO DEVICE - A method and device may control energy consumption of in an in vivo imaging device by determining or estimating an amount of energy needed to capture images at a frame rate until a complete passage of the device through a predetermined region of the gastrointestinal tract, and alter or limit the frame capture rate accordingly. | 2015-03-12 |
20150073214 | ENDOSCOPE SYSTEM HAVING CONNECTOR - An endoscope system includes an endoscope and a cleaning adapter or connector. The endoscope has a port device or end sleeve, to which the cleaning adapter is coupled. The cleaning adapter includes a connector housing and a coupling sleeve, which has a male tapered portion. The connector housing includes a female thread (fastening device) and a guide surface. The port device includes a flange and a male thread. The guide surface guides the port device by contacting the flange. Thus, a male tapered surface or tapered sealing surface is axially aligned with a female tapered surface or tapered bore surface. The male tapered surface tightly contacts the female tapered surface by threaded engagement between the male and female threads. Accordingly, air-tightness or liquid-tightness can be ensured even in use of a plurality of connectors couplable selectively for connecting a related apparatus. | 2015-03-12 |
20150073215 | ENDOSCOPE OVERTUBE - Disclosed is an endoscope overtube such that friction during turning can be reduced. The endoscope overtube of the present invention has a first insertion passage into which an endoscope can be inserted, and has a second insertion passage into which a treatment instrument can be inserted, in a wall constituting the first insertion passage, wherein the second insertion passage has, on a side face thereof, an opening which passes through a surface of the overtube. | 2015-03-12 |
20150073216 | ENDOSCOPE FOR TISSUE DISSECTION AND VISUALIZATION - One aspect of the present disclosure relates to an endoscope for facilitating a medical procedure by creating an anatomic space in or adjacent a target bodily tissue to be imaged. The endoscope can comprise a flexible, elongate tubular member defining a central lumen and an expandable dissecting member coupled to a distal end of the tubular member. The tubular member can further include at least one imaging channel extending longitudinally therethrough. The at least one imaging channel can include a visualization system for conveying an image from the distal end of the tubular member to a user. The expandable dissecting member can define a channel in fluid communication with the central lumen of the tubular member. The expandable dissecting member can extend beyond the distal end of the tubular member. | 2015-03-12 |
20150073217 | INTELLIGENT ENDOSCOPY SYSTEMS AND METHODS - Endoscope sheaths and associated endoscopy data collection and analysis systems and methods are described. In one implementation an endoscope sheath include a body and one or more sensors disposed in the body. The sheath may further include a leak detection apparatus configured to detect leaks in the sheath body. In addition, the sheath may include actuator apparatus, such as a balloon catheter or other surgical instrument. Data from the endoscope and endoscope sheath may be collected, fused and displayed for use in medical procedures and/or analysis. | 2015-03-12 |
20150073218 | ENDOSCOPIC DEVICE INCLUDING CLEANING MECHANISM - In a cleaning mechanism provided in an insertion section of an endoscopic device, two straight lateral faces obliquely and straightly extending toward the center side of a cylindrical lens are joined to a laterally circumferential face, a pedestal section inside which a liquid-sending route of a cleaning liquid, and a gas-sending route are internally provided is arranged, and an angle which a gushing direction of the cleaning liquid gushed from each of wash nozzles provided on the lateral faces toward the laterally circumferential face forms with a perpendicular line passing through the center of the cylindrical lens is an acute angle, the gushed cleaning liquid intersecting the perpendicular line. | 2015-03-12 |
20150073219 | STEREOSCOPIC ENDOSCOPE - A stereoscopic endoscope includes an imaging optical system including a diaphragm which adjusts light intensity and a pupil splitting polarizing element that has a pair of polarizers which are disposed to line up along a splitting line as a boundary; a scope holder in which at least the pupil splitting polarizing element is disposed in an inner portion thereof; and an imaging device on which light is incident via the imaging optical system. Light which is incident on the pupil splitting polarizing element is polarized by the pair of polarizers in order to generate a right eye image and a left eye image, respectively. A direction that is perpendicular to both the splitting line and an optical axis is a positioning direction. Positioning portions are provided to position the pupil splitting polarizing element in relation to a conjugate position of the diaphragm, or a proximity thereof, in the positioning direction. | 2015-03-12 |
20150073220 | Endoscopic Camera Component Manufacturing Method - The invention provides an endoscope having a lens holder, wherein the lens holder includes a body containing a sintered feedstock and machined surfaces. The invention also provides a method of manufacturing the endoscope which includes the steps of molding a metal blank by a MIM process, wherein the metal blank is “near net shape” and has a sprue, a post, and optionally an outer shell, machining the inner surfaces and then the outer surfaces of the metal blank to form a lens holder, installing a lens in the lens holder, and assembling the lens holder having the lens into the endoscope. | 2015-03-12 |
20150073221 | DUAL CHANNEL SURGICAL DEVICE FOR ABDOMEN ACCESS - A trocar for performing laproscopic surgery is disclosed. The trocar is equipped with a double channel allowing the simultaneous introduction of an optical instrument and a grasping or cutting instrument. Furthermore, the introduction of a movable two-way valve allows the rapid emptying of the abdomen or the removal of important anatomical pieces, if necessary. | 2015-03-12 |
20150073222 | TROCAR - A trocar includes a plate member having a first surgical instrument port formed therein, a movable port that is provided separately from the plate member, and a cylinder part that is provided at the plate member and attached to an incised wound. | 2015-03-12 |
20150073223 | TROCAR CANNULA ASSEMBLY AND METHOD OF MANUFACTURE - A cannula assembly having a retention member and a method of manufacture of the cannula assembly is provided. The cannula assembly includes a cannula and a sleeve disposed around the cannula from a proximal end to a distal end. The sleeve can be pre-formed by a stretch blow molding process then advanced over the cannula. The sleeve includes an inflatable balloon and an annular ring distal the inflatable balloon. The cannula includes an annular recess. The annular ring is sized to have an interference fit with the annular recess. | 2015-03-12 |
20150073224 | SYSTEM FOR MYOMECTOMY AND MORCELLATION - A method for dissecting a myoma from a uterine wall includes inserting a myomectomy screw retractor into a surgical site, articulating a tool assembly positioned at a distal end of the myomectomy screw retractor such that a screw of the tool assembly is positioned adjacent to the myoma orthogonal to the uterine wall, rotating the screw of the tool assembly into the myoma until the screw is substantially engaged with the myoma, manipulating the myoma by pitching, rotating, and/or providing traction to the myoma to expose cutting planes, and dissecting the myoma from the uterine wall by cutting along the exposed cutting planes. | 2015-03-12 |
20150073225 | RETRACTOR ILLUMINATION SYSTEM - An apparatus for the efficient provision of directed illumination to a subdermal surgical field that is attachable to or completely forms a surgical retractor blade. | 2015-03-12 |
20150073226 | BLADE INSERT ILLUMINATOR - A blade insert illumination system includes one or more illumination elements composed of a transparent or semitransparent polymer that is preferably biocompatible and sterilizable. The illumination elements operate as a waveguide and may incorporate optical components such as, for example, facets, lenses, gratings, prisms and or diffusers to operate as precision optics for customized delivery of the light energy. The illumination elements may be modular, allowing components to be mixed and matched for different sizes of blade retractors, or may be a single integrated unit. | 2015-03-12 |
20150073227 | SURGICAL ILLUMINATOR - The present invention provides a surgical illuminator. The surgical illuminator includes: a cylindrical lens barrel, a base, a printed circuit board, a light emitting diode, an aspheric lens, and a double-convex lens. Methods of using the surgical illuminator are also provided. | 2015-03-12 |
20150073228 | ULTRA LOW POWER INTERFACE USING ADAPTIVE SUCCESSIVE APPROXIMATION REGISTER - A medical device and associated method convert an analog signal using an adaptable bit number. The medical device includes an analog-to-digital (A/D) converter for receiving an analog signal. The A/D converter has a full scale range and a total number of bits spanning the full scale range. The A/D converter converts the analog signal to a digital signal over conversion cycles using an adaptable bit number so that on at least a portion of the conversion cycles an adapted number of bits spanning a portion of the full scale range less than the total number of bits is used by the A/D converter to convert the analog signal. | 2015-03-12 |
20150073229 | SWALLOWING MOTOR FUNCTION MEASUREMENT AND ASSESSMENT TOOLS, METHODS, AND APPARATUS - Tools, methods and apparatus are provided that may be used to identify ineffective swallowing in the subject, including ineffective swallowing due to an obstruction, and may further be used to determine risk of aspiration in the subject. In one aspect, a method includes accessing intraluminal impedance measurements and pressure measurements obtained from the pharynx and/or esophagus of a subject during clearance of a bolus from the mouth and/or throat of the subject. The method further includes combining and analyzing the intraluminal impedance and pressure measurements to derive a value for one or more pressure-flow variables in the pharynx and/or esophagus on the subject. The swallowing motor function in the subject is assessed by comparing the value of the pressure-flow variables with a predetermined pharyngeal and/or esophageal reference value for the one or more pressure-flow variables. | 2015-03-12 |
20150073230 | CALCULATING BLOOD PRESSURE FROM ACOUSTIC AND OPTICAL SIGNALS - A device configured to monitor blood pressure includes an audio sensor, an optical sensor, and a processing device. The audio sensor is configured to generate an audio data signal representing a heartbeat of a subject over time. The optical sensor is configured to generate an optical data signal representing blood volume within a blood vessel of the subject over time. The processing device is configured to calculate a pulse wave transit time (PWTT) based on the audio data signal and the optical data signal. The processing device is also configured to calculate a blood pressure of the subject based on the PWTT. | 2015-03-12 |
20150073231 | INTEGRATED WIRELESS PATCH FOR PHYSIOLOGICAL MONITORING - A sensor system in accordance with the present invention comprises a plane member a plurality of electrodes within the plane member adapted to contact a human body to detect and monitor human generated voltages. The sensor can be applied to monitor a variety of applications relating to health disease progression fitness and wellness. Some of the specific applications include the monitoring of ECG EEG EMG glucose electrolytes body hydration dehydration tissue state and wounds. Various aspects of the invent aspects of the invention are shown by illustrating certain embodiments. Many other embodiments can be used to implement the invented schemes. | 2015-03-12 |
20150073232 | DEVICES AND METHODS FOR AIRFLOW DIAGNOSIS AND RESTORATION - Devices for monitoring patient breaching comprise a collar having a microprocessor and memory which is connectable to a plurality of sensors. Therapeutic devices comprise similar diagnostic capabilities and further provide energy delivery elements for stimulating a patient's upper respiratory muscles in order to terminate and an apneic or snoring event. | 2015-03-12 |
20150073233 | SYSTEMS AND METHODS FOR PHYSIOLOGICAL MONITORING USING MULTIPLE SIGNAL PROCESSING DEVICES - Provided according to embodiments of the invention are systems for monitoring a physiological state of an individual that include a PPG sensor, which optionally includes an auxiliary physiological sensor integrated with or connected thereto; a first signal processing device in electronic communication with the PPG sensor, whereby the PPG sensor transmits PPG signals to the first signal processing device; and a second signal processing device that detects at least a portion of the signals transmitted by the PPG sensor to the first signal processing device, at least a portion of signals transmitted by the auxiliary physiological sensor, or both. Related methods are also provided herein. | 2015-03-12 |
20150073234 | SYSTEMS AND METHODS FOR MONITORING HEART FUNCTION - Characteristics of a user's heart are detected. In accordance with an example embodiment, a ballistocardiogram (BCG) sensor is used to detect heart characteristics of a user, and provide a BCG output indicative of the detected heart characteristics. The BCG output is further processed using data from one or more additional sensors, such as to reduce noise and/or otherwise process the BCG signal to characterize the user's heart function. | 2015-03-12 |
20150073235 | PHYSICAL ACTIVITY MONITOR AND DATA COLLECTION UNIT - A physical activity data collection unit includes one or more infrared sensors configured to provide an output indicative of a pulse rate of a user of the physical activity data collection unit, at least one temperature sensor configured to provide an output indicative of at least a body temperature of the user, and at least one accelerometer configured to provide an output indicative of movements of the user, The physical activity data collection unit can also include a microcontroller configured to determine a pulse rate, a body temperature, and movement characteristics of the user of the data collection unit based on outputs from the one or more infrared sensors, the at least one temperature sensor, and the at least one accelerometer; determine a physical exertion level of the user based on one or more of the pulse rate, the body temperature, or the movement characteristics of the user; and store, in a memory, data indicative of the physical exertion level during a time period during which the physical exertion level exceeds a predetermined threshold. | 2015-03-12 |
20150073236 | Physiological Monitoring Methods - A monitoring device includes a housing configured to be attached to a body of a subject. An optical emitter, optical detector, and sensor for measuring motion noise are located within the housing. Light transmissive material is in optical communication with the optical emitter and detector and is configured to deliver light from the optical emitter to one or more locations of the body of the subject and to collect light external to the housing and deliver the collected light to the detector. A signal processor is configured to receive and process signals produced by the optical detector and the motion noise sensor, and to remove noise from the signals produced by the optical detector. The signal processor may generate physiological parameters for the subject such as heart rate, blood flow, blood pressure, VO | 2015-03-12 |
20150073237 | DETECTING, QUANTIFYING, AND/OR CLASSIFYING SEIZURES USING MULTIMODAL DATA - Methods, systems, and apparatus for detecting an epileptic event, for example, a seizure in a patient using a medical device. The determination is performed by providing an autonomic signal indicative of the patient's autonomic activity; providing a neurologic signal indicative of the patient's neurological activity; and detecting an epileptic event based upon the autonomic signal and the neurologic signal. | 2015-03-12 |
20150073238 | SENSOR INSERTION DEVICE AND METHOD FOR OPERATING SAID DEVICE - A sensor inserting device includes a device main body and a push handle for moving a detector of a sensor and an insertion needle, with the sensor held coupled to the insertion needle, into the body of a patient. A transmitter, for processing a signal from the sensor, is set in the device main body. A cable, allowing transmission of a signal between the sensor and the transmitter, is connected to the sensor ( | 2015-03-12 |
20150073239 | CONTINUOUS CUFFLESS BLOOD PRESSURE MEASUREMENT USING A MOBILE DEVICE - A mobile blood pressure monitor is described that includes an integrated acoustic device, an optical sensor including at least one of a light source or a pulse oximeter device, and control circuitry coupled to the integrated acoustic device and the optical sensor. Additionally, a mobile electronic device configured to measure blood pressure is described that includes a mobile system and a mobile blood pressure monitor as disclosed above. In implementations, a process for measuring blood pressure includes sensing a heart sound with an integrated acoustic device, measuring a blood pulse rate at a peripheral site with an optical sensor, calculating a pulse wave transit time using a sensed heart sound and a measured blood pulse rate, and correlating a blood pressure using the heart sound and the blood pulse rate. | 2015-03-12 |
20150073240 | Implantable Real-Time Oximeter To Determine Potential Strokes And Post-Traumatic Brain-Injury Complications - A first embodiment of an oximetry probe is attached around a blood vessel near the site of a likely stroke. That will be useful to monitor large and medium size cerebral arteries. Another type of pulse oximeter can be passed within cerebral blood vessels to monitor the oxygenation status of the surrounding cerebral tissues. In that version, the emitter and detector are coplanar and contained in a small area, e.g., 50-12 μm. | 2015-03-12 |
20150073241 | MEDICAL DEVICE MANAGEMENT SYSTEM - The present disclosure provides systems and methods for calibrating medical devices and processing physiological measurements using a medical device management system. As an example, the medical device can be a handheld glucometer configured for invasive testing and non-invasive testing of physiological parameters of a patient. | 2015-03-12 |
20150073242 | METHOD FOR DETERMINING GLUCOSE CONCENTRATION IN HUMAN BLOOD - Measuring the impedance of a human body region at a high frequency (Z | 2015-03-12 |
20150073243 | Method and Apparatus for Providing Glycemic Control - Methods and system to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided. | 2015-03-12 |
20150073244 | DETERMINATION AND APPLICATION OF GLUCOSE SENSOR RELIABILITY INDICATOR AND/OR METRIC - Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor. | 2015-03-12 |
20150073245 | System and method for measuring force and torque applied to a catheter electrode tip - A contact sensing assembly including a catheter including an electrode having a base portion mounted adjacent a head portion of the catheter body. A sensor is disposed adjacent the base portion for measuring compression or tensile forces applied to an electrode tip portion, and includes a predetermined sensitivity. The base and head portions include predetermined rigidity so that forces applied to the electrode tip portion are determinable as a function of the sensitivity and a sensor output. A contact sensing assembly also includes an electrode pipe operatively connected to the catheter body for movement and bending with the catheter body, and an electrode wire disposed in the electrode pipe and including isolation. A change in capacitance resulting from movement of the electrode wire toward the electrode pipe or contact of the electrode wire with the electrode pipe during bending of the catheter correlates to a force applied to the catheter. | 2015-03-12 |
20150073246 | METHOD FOR MAPPING VENTRICULAR/ATRIAL PREMATURE BEATS DURING SINUS RHYTHM - While detecting a cardiac arrhythmia, a mapping electrode of a probe is used to associate a local activation time with a first location in a region of interest in the heart. While detecting an absence of the cardiac arrhythmia, the local activation time is associated with a second location in the heart. Electrical data of the first location is assigned to the second location, and an electroanatomic map of the heart is generated that includes the second location in association with the assigned electrical data of the first location. | 2015-03-12 |
20150073247 | IMPLANTABLE MEDICAL DEVICES WITH POWER SUPPLY NOISE ISOLATION - The present invention provides an implantable medical device having at least two electrodes coupled to the device housing. The electrodes may be configured for sensing physiological signals such as cardiac signals and alternatively for providing an electrical stimulation therapy such as a pacing or defibrillation therapy. In accordance with aspects of the disclosure, the device housing provides a hermetic enclosure that includes a battery case hermetically coupled to a circuit assembly case. At least one of the at least two electrodes is coupled to an exterior surface of the battery case. The battery case is electrically insulated from the cathode and anode of the battery. | 2015-03-12 |
20150073248 | IMPLANTABLE ACTIVE FIXATION LEAD WITH BIODEGRADABLE HELICAL TIP - Described is an implantable lead comprising a flexible body extending between a proximal end and a distal end and a distal assembly coupled to the distal end of the body. The distal assembly includes a housing having a distal end and a proximal end, the proximal end fixedly coupled to the distal end of the lead body, a coupler rotatably disposed within the housing, the coupler having a proximal end and a distal end, and a helical electrode fixedly secured to the distal end of the coupler. The helical electrode comprises a proximal axial length portion that comprises a non-degradable material, and a distal axial length portion that comprises a biodegradable material. The coupler and the helical electrode are configured to rotate and therefore translate relative to the housing. | 2015-03-12 |
20150073249 | BRAIN FUNCTION ACTIVITY LEVEL EVALUATION DEVICE AND EVALUATION SYSTEM USING IT - Discrete Fourier transform is performed on an output of each brain potential sensor, which measure a subject's brain potential, for each segment in order to obtain a discrete Fourier coefficient that has a frequency component. A mean value of squares of absolute values of Fourier coefficients is obtained. The Fourier coefficients are normalized using the mean value for obtaining a normalized power spectrum NPS;j,m. Mean values of squares of absolute values of Fourier coefficients of adjoining frequency components in all the segments is normalized using a square value of the mean values of the adjoining frequency components for obtaining a normalized power ratio NPV;j,m. Two markers sNAT;j,m and vNAT;j,m are derived from the power spectrum and power ratio for evaluating a brain function activity level. | 2015-03-12 |