06th week of 2013 patent applcation highlights part 32 |
Patent application number | Title | Published |
20130034796 | ELECTROLYTE SHEET FOR SOLID OXIDE FUEL CELL, METHOD OF PRODUCING THE SAME, SINGLE CELL FOR SOLID OXIDE FUEL CELL, AND SOLID OXIDE FUEL CELL - The electrolyte sheet for solid oxide fuel cell of the present invention has different surface roughnesses between the peripheral region and the region other than the peripheral region at least on one side. The surface roughness Ra(b) in the peripheral region is at least 0.05 μm and less than 0.3 μm. The surface roughness Ra(i) in the region other than the peripheral region is at least 0.2 μm and at most 1.2 μm. And, the ratio of Ra(i) to Ra(b) (Ra(i)/Ra(b)) is more than 1 and at most 4. Here, the surface roughness Ra(b) and the surface roughness Ra(i) are arithmetic mean roughness values and determined by an optical and laser-based non-contact three-dimensional profile measuring device in accordance with a German standard ‘DIN-4768’. | 2013-02-07 |
20130034797 | BIPOLAR PLATE ASSEMBLY HAVING AN ENCAPSULATED EDGE - A bipolar plate assembly includes at least one bipolar plate and an insert member in engagement with the at least one bipolar plate. The insert member has an encapsulant encapsulating at least a portion thereof. | 2013-02-07 |
20130034798 | FUEL CELL WATER MANAGEMENT ARRANGEMENT - An example fuel cell device includes an electrode assembly having two gas diffusion layers (GDLs). One GDL is adjacent to the anode electrode and the other GDL is adjacent to the cathode electrode. Seals on the periphery of the GDLs are configured to block reactant gases from direct mixing within the GDLs. Sealing the perimeter of the GDLs blocks liquid-water flow from exiting the gas diffusion layer. The disclosed example provides an opening in the seal near a fluid exit area of the fuel cell that provides a path for communicating water from the active area through a perimeter portion of the GDL. An example method of managing fluid in a fuel cell includes providing an opening in a perimeter seal of a GDL of the fuel cell. The method communicates a fluid through a channel in the plate and moves water through the opening using the fluid. | 2013-02-07 |
20130034799 | BIPOLAR PLATE ASSEMBLY HAVING A RECESS AND AN INSERT MEMBER FOR PLACEMENT IN THE RECESS - A bipolar plate assembly includes a first bipolar plate and a second bipolar plate. The second bipolar plate has a recess. An insert member is disposed between the first and second bipolar plates and within the recess of the second bipolar plate. | 2013-02-07 |
20130034800 | BIPOLAR PLATE ASSEMBLY HAVING AN INSERT MEMBER - A bipolar plate assembly includes at least one bipolar plate and at least one insert member configured for face-to-face engagement with the at least one bipolar plate. The at least one insert member has a preformed cutout. | 2013-02-07 |
20130034801 | BIPOLAR PLATE ASSEMBLY HAVING AN ADJUSTMENT MEMBER - A bipolar plate assembly includes a first bipolar plate and a second bipolar plate having a recess therein. An insert member is disposed between and in engagement with the first and second bipolar plates and located in the recess in the second bipolar plate. An adjustment member adjusts the engagement between the insert member and at least one of the first and second bipolar plates. | 2013-02-07 |
20130034802 | SOLID OXIDE FUEL CELL AND MANUFACTURING METHOD THEREOF - A solid oxide fuel cell and a manufacturing method thereof are disclosed. A solid oxide fuel cell includes first and second electrode formed opposite to each other and an electrolyte layer formed between the first and the second electrodes. Either the first electrode or the second electrode may include between about 1 to about 20 wt % of a thermoelectronic material configured to increase thermal emission of electrons with an increase in temperature. | 2013-02-07 |
20130034803 | Electrochemical Synthesis of Elongated Noble Metal Nanoparticles, such as Nanowires and Nanorods, on High-Surface Area Carbon Supports - Elongated noble-metal nanoparticles and methods for their manufacture are disclosed. The method involves the formation of a plurality of elongated noble-metal nanoparticles by electrochemical deposition of the noble metal on a high surface area carbon support, such as carbon nanoparticles. Prior to electrochemical deposition, the carbon support may be functionalized by oxidation, thus making the manufacturing process simple and cost-effective. The generated elongated nanoparticles are covalently bound to the carbon support and can be used directly in electrocatalysis. The process provides elongated noble-metal nanoparticles with high catalytic activities and improved durability in combination with high catalyst utilization since the nanoparticles are deposited and covalently bound to the carbon support in their final position and will not change in forming an electrode assembly. | 2013-02-07 |
20130034804 | HYBRID POROUS CARBON FIBER AND METHOD FOR FABRICATING THE SAME - Disclosed is a hybrid porous carbon fiber and a method for fabrication thereof. Such fabricated porous carbon fibers contain a great amount of mesopores as a porous structure readily penetrable by electrolyte. Accordingly, the hybrid porous carbon fibers of the present disclosure are suitable for manufacturing electrodes with high electric capacity. | 2013-02-07 |
20130034805 | HOLOGRAM RECORDING MATERIAL AND HOLOGRAM RECORDING MEDIUM - A hologram recording material includes a polymerizable monomer (A) that is active in radical polymerization but is substantially inactive in cationic polymerization, a polymerizable monomer (B) that is active in cationic polymerization but is substantially inactive in radical polymerization, and an initiator system (C) that polymerizes at least one of the polymerizable monomer (A) and the polymerizable monomer (B) through irradiation with light. The polymerizable monomer (A) and the polymerizable monomer (B) each have, in its structure, a moiety selected from the group consisting of aromatic rings, halogen atoms other than a fluorine atom, and sulfur atoms not derived from a cyclic sulfide or a mercapto group. A hologram recording medium includes a recording layer composed of the hologram recording material. | 2013-02-07 |
20130034806 | PHOTOMASK MAKING METHOD, PHOTOMASK BLANK AND DRY ETCHING METHOD - A photomask is manufactured by providing a photomask blank comprising a transparent substrate, a phase shift film, and a light-shielding film, the phase shift film and the light-shielding film including silicon base material layers, a N+O content in the silicon base material layer of the phase shift film differing from that of the light-shielding film, and chlorine dry etching the blank with oxygen-containing chlorine gas in a selected O/Cl ratio for selectively etching away the silicon base material layer of the light-shielding film. | 2013-02-07 |
20130034807 | Method and System for Design of a Reticle to be Manufactured Using Variable Shaped Beam Lithography - A method for fracturing or mask data preparation or proximity effect correction of a pattern to be formed on a surface is disclosed in which a plurality of variable shaped beam (VSB) shots are determined, and in which charged particle beam simulation is used to calculate the pattern which the plurality of VSB shots will form on the surface. At least two shots in the plurality of VSB shots overlap each other. In some embodiments, assigned dosages of at least two shots differ before proximity effect correction (PEC). In other embodiments an optimization technique may be used. | 2013-02-07 |
20130034808 | PULVERIZER, PULVERIZATION METHOD, TONER PRODUCTION METHOD, AND TONER - A pulverizer including a solid-gas mixer to mix a compressed gas and particles of a raw material to be pulverized to prepare a solid-gas mixture; a particle path controlling nozzle connected with the solid-gas mixer to feed the solid-gas mixture fed from the solid-gas mixer while accelerating the solid-gas mixture and controlling the particles of the raw material so as to choose different flow paths based on particle diameters of the particles of the raw material; a collision member; and an accelerating tube connected with the particle path controlling nozzle to further accelerate the solid-gas mixture fed from the particle path controlling nozzle while maintaining the flow paths of the particles and ejecting the accelerated solid-gas mixture toward the collision member to pulverize the raw material. | 2013-02-07 |
20130034809 | NONAQUEOUS DISPERSION OF RESIN PARTICLES - Provided is a nonaqueous dispersion of resin particles, in which the resin particles have uniform particle diameters and shapes and which exhibits excellent fixing properties, particularly when used as a liquid electrophotographic developer. More specifically, provided is a nonaqueous dispersion (X) in which resin particles (C) are dispersed in a nonhydrophilic organic solvent (L) that exhibits a relative permittivity of 1 to 4 at 20° C., the resin particles (C) being core-shell type resin particles each of which comprise a resin particle (B) that contains a resin (b) and fine particles (A) that contain a resin (a) and that either adhere to the surface of the resin particle (B) or form a film on the surface of the resin particle (B), wherein the solubility of (a) in (L) at 25° C. is 10 wt % or less relative to the weight of (a). | 2013-02-07 |
20130034810 | METHOD OF MANUFACTURING TONER, APPARATUS FOR MANUFACTURING TONER, AND METHOD OF MANUFACTURING RESIN PARTICLES - A method of manufacturing toner is provided. In the method, toner constituents are dissolved or dispersed in an organic solvent to prepare a toner constituents liquid. The toner constituents liquid is degassed so that the toner constituents liquid includes dissolved oxygen in an amount of 3 mg/L or less. The toner constituents liquid is vibrated in a chamber having at least one nozzle to form a liquid column resonance standing wave in the toner constituents liquid. The toner constituents liquid is discharged from the nozzle disposed within an area including an antinode of the liquid column resonance standing wave to form the toner constituents liquid into liquid droplets. The liquid droplets are dried to solidify the liquid droplets into solid particles. | 2013-02-07 |
20130034811 | METHOD FOR PROVIDING AN ORDERED LAYER OF SELF-ASSEMBLABLE POLYMER FOR USE IN LITHOGRAPHY - A method for providing an ordered polymer layer at a surface of a substrate includes depositing a self-assemblable polymer layer directly onto a primer layer on a substrate to provide an interface between the self-assemblable polymer layer and the primer layer, and treating the self-assemblable polymer layer to provide self-assembly into an ordered polymer layer, such as a block copolymer, having first and second domain types at the interface. The primer layer is adapted to improve its chemical affinity to each domain type at the interface, in response to the presence of the respective domain type in the self-assembled polymer at the interface during the self-assembly of the self-assemblable polymer layer into the ordered polymer layer. This may lead to reduction in defect levels and/or improved persistence length for the ordered polymer layer. The method may be useful for forming resist layers for use in device lithography. | 2013-02-07 |
20130034812 | POLYMERIZABLE COMPOSITION FOR SOLDER RESIST, AND SOLDER RESIST PATTERN FORMATION METHOD - The present invention provides a polymerizable composition for a solder resist, including an infrared ray shielding material, a polymerization initiator, and a polymerizable compound, and a solder resist pattern forming method using the polymerizable composition for a solder resist. | 2013-02-07 |
20130034813 | CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION FOR ArF IMMERSION LITHOGRAPHY AND PATTERN FORMING PROCESS - A chemically amplified positive resist composition comprising (A) a sulfonium salt of 3,3,3-trifluoro-2-hydroxy-2-trifluoromethylpropionic acid, (B) an acid generator, (C) a base resin, and (D) an organic solvent is suited for ArF immersion lithography. The carboxylic acid sulfonium salt is highly hydrophobic and little leached out in immersion water. By virtue of controlled acid diffusion, a pattern profile with high resolution can be constructed. | 2013-02-07 |
20130034814 | SILANE-BASED COMPOUNDS AND PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME - The present application relates to a new silane-based compound, a photosensitive resin composition including the same, and a photosensitive material including the same. The photosensitive resin composition including the silane-based compound according to the exemplary embodiment of the present application increases adhesion strength to a substrate, such that a developing property is excellent and there are no surface stains or defects during a subsequent process. Accordingly, a photosensitive material, a color filter and the like having excellent quality may be manufactured by using the photosensitive resin composition according to the exemplary embodiment of the present application. | 2013-02-07 |
20130034815 | METHODS FOR PREPARING LITHOGRAHIC PRINTING PLATES - A lithographic processing solution has a pH of less than 12 and comprises at least 0.001 and up to and including 1 weight % of a water-soluble or water-dispersible, non-IR-sensitive compound that has a heterocyclic moiety with a quaternary nitrogen in the 1-position of the heterocyclic ring, and has one or more electron donating substituents attached to the heterocyclic ring, at least one of which electron donating substituents is attached in the 2-position. This processing solution can be used to develop both single-layer and multi-layer positive-working lithographic printing plate precursors that have been imaged using infrared radiation. | 2013-02-07 |
20130034816 | Conductive Vias In A Substrate - A method of forming a conductive via in a substrate includes forming a via hole covered by a dielectric layer followed by an annealing process. The dielectric layer can getter the mobile ions from the substrate. After removing the dielectric layer, a conductive material is formed in the via hole, forming a conductive via in the substrate. | 2013-02-07 |
20130034817 | Afterburner for gas from gassification plant - The present invention relates to an afterburner for gas from a gasification plant. The afterburner provides an optimal mixture of combustible gas and air, permitting an optimal reaction between the O2 in the air and the gas and creating a mixture ratio that enables the load on a burner to be regulated without altering the mixture ratio between air and gas. This offers the possibility of optimal combustion even during regulation of the burner, over the whole of the relevant regulating range. The result is extremely good combustion and reduced emissions of O2, CO and NOx. | 2013-02-07 |
20130034818 | Passive Thermal Impedance Matching Using Common Materials - A device and method for dissipating heat from a source of heat is described. A plurality of layers of thermally conductive materials receives a flow of heat from a source of heat. A first layer of the plurality of layers receives the flow of heat from the source of heat and redirects and transfers the flow of heat to a second of the plurality of layers. Each layer has a separate preselected thermal impedance to control a desired temperature change across the plurality of layers and to maintain a desired operating temperature of the source heat. | 2013-02-07 |
20130034819 | Delayed Coking Process - A delayed coking heater for heating a feedstock to delayed coking temperature is disclosed. The delayed coking heater may include: a heater including a radiant heating zone comprising a lower portion including a hearth burner section and an upper portion including a wall burner section, the hearth burner section comprising a plurality of hearth burners located adjacent to the bottom hearth for firing in the radiant heating zone; and the wall burner section comprising a plurality of wall burners located adjacent to opposing walls; and a multiple parallel serpentine heating coil located in the radiant heating zone. | 2013-02-07 |
20130034820 | HEAT TREATMENT APPARATUS - A heat treatment apparatus for performing heat treatment of processing objects at a time without changing the interior configuration of a conventional clean room even when the processing objects are large-sized. The heat treatment apparatus is installed in a clean room. The heat treatment apparatus includes: a heat treatment furnace including a vertical processing chamber having a furnace opening at the top and adapted to house and heat-treat processing objects, a heat insulator that surrounds the circumference of the processing chamber, and a heater provided on the inner peripheral surface of the heat insulator; a lid for closing the furnace opening of the processing chamber; and a holding tool, hung via a heat-retaining cylinder from the lid, for holding the processing objects in multiple stages. The heat treatment furnace of the heat treatment apparatus, for the most part in the height direction, lies beneath the floor of the clean room. | 2013-02-07 |
20130034821 | Conveyor Oven - A conveyor oven is described. The conveyor oven includes a frame made of load-bearing structural members. The conveyor oven has a modular construction, with the structural members defining a rectangular prism. Blocks of insulation are placed in the frame openings, and a flexible insulating material, such as a multi-layer insulating textile, is used to cover joints between adjacent modules. Along the length of the conveyor oven, idler rollers that support the conveyor belt have ends that penetrate the sides of the oven and are supported such that the rollers can shift as the oven expands and contracts without creating openings for heat or air leakage. Air flow within the oven is managed using sets of adjustable baffle plates above and below the conveyor belt. | 2013-02-07 |
20130034822 | ORTHODONTIC ATTACHMENT DEVICE SYSTEMS AND METHODS - Embodiments presented herein are directed to accurately coupling attachment devices to dental surfaces suitable for cooperative engagement with positioning appliances. In accordance with an embodiment, a system is provided that comprises a template, one or more preformed attachment devices, and one or more gaskets. The template is operable for accurate locating and positioning of the preformed attachment device onto the tooth surface. The gasket is operable to mask unintended tooth surface adjacent the preformed attachment device from bonding material. The preformed attachment device is operable to facilitate secure bonding to the tooth surface via bonding material. | 2013-02-07 |
20130034823 | ADAPTIVE ILLUMINATION METHOD AND APPARATUS FOR DENTAL SHADE MATCHING - An intra-oral imaging apparatus for obtaining an image of a tooth has an image capture apparatus with an imaging sensor that is energizable to obtain image data and one or more optical elements for directing light from the tooth to the imaging sensor. An illumination apparatus has one or more light sources energizable to emit light and a spatial light modulator that is configurable to shape an illumination beam from the emitted light. One or more optical elements relay the shaped illumination beam toward the tooth surface. A control logic processor in signal communication with the imaging sensor obtains image data and in signal communication with the spatial light modulator shapes the illumination beam according to the obtained image data. | 2013-02-07 |
20130034824 | DENTAL LIGHT CURING DEVICE WITH IMPROVED HEAT DISSIPATING MECHANISM - A light curing device used to solidify resin with a particular wavelength of beam comprising a shell, a heat sink, a light curing device and an air guide unit. The shell has an air inlet at the extremity and several air outlets around the side wall thereof. The heat sink is inside the shell. The light source device which is disposed inside the shell and at another extremity has at last one light unit closed the heat sink. The air guide unit is disposed inside the air inlet. The light curing device adapts an improved cooling structure to increase cooling efficiency, reduce the noise and vibration, and reduce unit weight. | 2013-02-07 |
20130034825 | Intraoral Imaging System - An intraoral imaging system includes a receiving module that communicates with an imaging display device. The imaging device includes handle having a transmitter module and a power source as well as neck and head portions that extend from the handle. The device includes a camera module that rotates in the distal and proximal direction to view and process still images and video. The camera module includes a movable image sensor to provide focus capability. The imaging device further includes a control assembly having a plurality of control members. The control assembly includes image capture controls that an operator engages in a lateral motion to capture images or video. A focus control member controls the spatial relationship between the image sensor and the stationary lens and an articulation control member to articulate the camera module to provide a greater range of imaging. | 2013-02-07 |
20130034826 | INTRAORAL INSPECTION APPARATUS AND METHOD FOR OPERATING INTRAORAL INSPECTION APPARATUS - Provided is an intraoral inspection apparatus for dental use capable of distinguishing and detecting more kinds of diseased sites etc. with one apparatus. The apparatus comprises: a light source unit provided with color-producing light sources capable of inducing fluorescent lights from diseased sites; a wavelength adjusting device provided with a first filter that transmits, among the fluorescent lights, a light having a wavelength of a fluorescent light from a predetermined diseased site and blocks or attenuates a light having a wavelength other than this, and provided with a second filter that transmits, among the fluorescent lights, a light having a wavelength of a fluorescent light from a diseased site different therefrom and blocks or attenuates a light having a wavelength other than this; and an imaging device which receives the fluorescent lights transmitted through the first filter and the second filter, and converts them into electrical signals. | 2013-02-07 |
20130034827 | DENTAL WEDGE - A dental wedge for use in the inter-proximal space between adjacent teeth is described. The wedge comprises a taper section ending at a tip, and a body section extending to the tapering section at one end. The body section has an inverted V-shaped cross-section, flexing of the sides of the V-shape allows the wedge to adapt to various contours of the inter-proximal space. The mid-portion of the body section is narrower than at least a portion of the wedge either end of the mid-portion. | 2013-02-07 |
20130034828 | Dynamically Generated Dental Articulator Controls - This invention relates to improved methods and apparatus for recording and simulating the condylar movement of an individual. This invention also provides a dental articulator which is designed to simulate the jaw or condylar movements of a patient. This instrument enables a dentist to obtain the necessary diagnostic information for treatment of the occlusal irregularities, such as malocclusion, and the fabrication of dental cast or “dentures”. | 2013-02-07 |
20130034829 | NANO BUBBLE GENERATING NOZZLE AND ORAL CLEANING DEVICE INCLUDING THE SAME - Disclosed is a nano bubble generating nozzle including: a passage passing through an interior thereof to provide a flow path through which liquid flows; a nano bubble generating part corresponding to a part of the passage, and formed such that a cross-section of the nano bubble generating part becomes small and then large again along a flow path of liquid so that the nano bubble generating part has a pressure lower than an external pressure of the nozzle body; and a gas inlet formed in the nozzle body, and connected to the nano bubble generating part so that gas is introduced into the nano bubble generating part due to a difference between an external pressure of the nozzle body and a pressure in the nano bubble generating part. | 2013-02-07 |
20130034830 | INJECTOR FOR DENTAL IMPLANTS - The present invention relates to an injector for dental implants, comprising: a main body which is formed into an annular tube, the entirety of which is formed so as to have a gentle curvature, and the center of which has a through-hole; and a piston inserted into the through-hole of the main body so as to press the contents in the main body, wherein the piston is made of a flexible material which can be elastically transformed, and a packing is coupled to the leading end of the piston. The main body and the piston of the injector for dental implants according to the present invention have gentle curvatures, and therefore the leading end of the injector can be accurately positioned at a hole formed in the bone of a patient, and the contents in the injector can be easily injected into the hole formed in the bone without leaking to the outside. | 2013-02-07 |
20130034831 | DENTURE ATTACHMENT - A magnetic device includes a cylindrical portion and a flange portion. The cylindrical portion is mounted with a cylindrical shaped flexible sleeve. The sleeve is axially longer than the cylindrical portion and includes an outer peripheral concavo-convex portion. When one end of the sleeve is abutted on a flange portion, the other end of the sleeve is projected above an attractive surface to form a keeper housing recess. The sleeve is relatively moved in an axial direction of the magnetic device to be inserted into and removed from a top end of the cylindrical portion. The magnetic device is used under condition the sleeve is fitted, an outer side surface of the magnetic device including the outer peripheral concavo-convex portion of the sleeve and the flange portion abutted on the one end of the sleeve is embedded in a denture base, and the keeper housing recess is exposed. | 2013-02-07 |
20130034832 | Method for Manufacturing Dental Implant and Dental Implant - A dental implant comprises a titanium member composed of a sintered body made from titanium or titanium alloy; and a ceramic member composed of oxide-based ceramic, and the ceramic member fixed to the titanium member. The titanium member has a recess, and the ceramic member has a protrusion coupled to the recess and pores, and the titanium member covers the protrusion of the ceramic member. The protrusion has a cross-sectional area increasing portion whose cross-sectional area increases toward a dead-end portion of the recess in a direction away from a base end of the protrusion. The titanium member is firmly fixed and joined to the ceramic member in a state that a part of the titanium or the titanium alloy is penetrated into the pores of the protrusion of the ceramic member. | 2013-02-07 |
20130034833 | Disposable mouth chip - DMC - A disposable mouth article, with specialized micro-structure fashioned from predetermined biodegradable biopolymers in predetermined shape, color, and size with selected macro features enabling the embodiment to have a diversity of functions i.e. providing excellent oral cleaning power in a novel embodiment, convenient packaging, miniaturized, novel functional dynamic architecture for providing novel automatic brushing, providing a novel means of focused dental optoelectric therapy, providing novel means of drug delivery, providing novel insitu reactions, providing novel means for delivery of heat, gas, jet pressure, providing novel means for regulated dispensing of biologically active molecules, providing built-in safety mechanisms for use by prison inmates, providing novel solid expectorant, providing new means of advertising, providing new economy. | 2013-02-07 |
20130034834 | ELECTRONIC DEVICE AND METHOD FOR SIMULATING FLIGHT OF UNMANNED AERIAL VEHICLE - A method for simulating flight operations of an unmanned aerial vehicle (UAV) using an electronic device obtains movement data of the electronic device detected by an accelerator sensor of the electronic device, and converts the movement data of the electronic device into control signals. The method further adjusts the control signals using a physics engine of the electronic device, and simulates flight operations of the UAV by controlling flight statuses of a three dimensional (3D) virtual UAV in a 3D virtual scene on a display screen of the electronic device according to the adjusted control signals. | 2013-02-07 |
20130034835 | LEARNING DEVICE AVAILABLE FOR USER CUSTOMIZED CONTENTS PRODUCTION AND LEARNING METHOD USING THE SAME - Disclosed is a learning device available for user customized contents production and a learning method using the same capable of capable of allowing a user to directly record learning contents and learn while listening to and copying the recorded contents. The present disclosure can provide a formant of recorded contents and a formant of a user's speech when a user records and plays contents to be learned and copies the played contents and provides a matching rate of the formants, thereby performing pronunciation correction while progressing learning for the user desired contents | 2013-02-07 |
20130034836 | Systems, Devices, and/or Methods for Handheld Devices - Certain exemplary embodiments provide a cover adapted to partially enclose a handheld device. The cover can comprise a thermochromic material, which can be embedded in the cover. The thermochromic material can be adapted to change color and/or appearance responsive to a temperature change. In certain exemplary embodiments, the thermochromic material can be adapted to transfer heat from the handheld device to an environment surrounding the handheld device. | 2013-02-07 |
20130034837 | SYSTEMS AND METHODS FOR TRAINING AND ANALYSIS OF RESPONSIVE SKILLS - A method for training is disclosed. The method may include providing, by a computer system, and interactive graphical simulation that can elicit a response, from a user, specific to a responsive skill for which training is desired. Based upon the response collected by the computer system, a threshold performance level of the user in at least one subcomponent skill of the responsive skill may be determined. A difficulty level of the simulation may be set to a level above the threshold performance level of the subcomponent skill, so that subsequent use of the simulation targets training in the subcomponent skill in order to enhance performance of the user in the desired responsive skill. Systems and programs for training are also disclosed. | 2013-02-07 |
20130034838 | METHOD FOR PERFORMING IMPLANT SURGERY - The joint implant manufacturer obtains and compiles surgeon-specific surgical and supply preference information in relation to a supplied joint implant prior to surgery. The manufacturer designates and trains at least one surgical team member using the surgeon-specific preference information and then supplies the service of the surgical team member(s) together with the supplied joint implant and supplies. The surgical team member(s) perform surgical procedures on the patient to assist the surgeon in removing a defective joint and replacing it with the supplied implant in accordance with the surgeon's surgical preferences. | 2013-02-07 |
20130034839 | Computer Method And System Determining What Learning Elements Are Most Effective - Education is a very important topic and educators are constantly attempting to improve manners in which education is provided to student. However, Educators often disagree as to the best techniques for educating students. Further, as technology is increasing the manner in which education is performed must keep up and take advantage of the current and anticipated developments in technology. A problem that is faced by Educators is that there is no ability to easily test and implement techniques of educations. Embodiments of the present invention provide a method and system for conducting a controlled experiment to compare techniques of conveying information. The embodiments facilitate administration of the controlled experiment to a plurality of users via an online user interface. Using results of the controlled experiment, the embodiments determine a relative effectiveness of a technique for conveying information to at least one user of the plurality of users. | 2013-02-07 |
20130034840 | SELECTING SURVEY QUESTIONS - For selecting survey questions, a response module receives responses to first questions relating to at least two qualities of at least two characteristics. A plot module generates a scatter plot of the at least two qualities for each characteristic. A selection module selects second questions targeted to characteristics with characteristic plot values for the at least two qualities in a specified region of the scatter plot. | 2013-02-07 |
20130034841 | SYSTEMS AND METHODS FOR ISOLATING AND CHARACTERIZING TARGET MATERIALS OF A SUSPENSION - Systems and methods for isolating and characterizing various target materials of a suspension are disclosed. A suspension suspected of containing the target materials is added to a tube. A float with a specific gravity corresponding to that of the target material is inserted into the tube. The tube, float, and suspension are centrifuged together causing the various materials suspended in the suspension to separate into different layers along the axial length of the tube according to their specific gravities. The float and/or tube are configured to drive the various target materials to a region of space between the float and inner wall of the tube. | 2013-02-07 |
20130034842 | Systems and Methods for Analyzing Microbiological Substances - Disclosed are systems and methods for monitoring a fluid for the purpose of identifying microbiological content and/or microorganisms and determining the effectiveness of a microbiological treatment. One method of monitoring a fluid includes containing the fluid within a flow path, the fluid including at least one microorganism present therein, optically interacting electromagnetic radiation from the fluid with at least one integrated computational element, thereby generating optically interacted light, receiving with at least one detector the optically interacted light, and generating with the at least one detector an output signal corresponding to a characteristic of the fluid, the characteristic of the fluid being a concentration of the at least one microorganism within the fluid. | 2013-02-07 |
20130034843 | Molecular Determinants Associated with Enhanced Ability to Enter Cells Expressing CXCR4 - The invention provides a method for determining whether a human immunodeficiency virus is likely to be have enhanced ability to enter a cell expressing CD4 and CXCR4 relative to a reference HIV. In certain aspects, the methods comprise detecting one or more amino acids in an envelope protein of the HIV associated with enhanced ability to enter CD4- and CXCR4-expressing cells and determining that the HIV's ability to enter such cells is enhanced relative to a reference HIV, e.g., an HIV that does not comprise such amino acid(s). | 2013-02-07 |
20130034844 | ASSAY FOR MEASURING CELL-MEDIATED IMMUNORESPONSIVENESS - The present invention relates generally to the field of immunological-based diagnostic assays. More particularly, the present invention contemplates a method for measuring cell-mediated immunoresponsiveness. The present invention further enables determination of the immunosuppressive effects of disease conditions, therapeutic agents and environmental contaminants. The assay of the present invention is also capable of integration into pathology architecture to provide a diagnostic reporting system and to facilitate point of care clinical management. | 2013-02-07 |
20130034845 | BARRIERS FOR FACILITATING BIOLOGICAL REACTIONS - The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or hydrophobic barriers in sample separation, purification, modification, and analysis processes. | 2013-02-07 |
20130034846 | MOLECULAR BIOSENSORS CAPABLE OF SIGNAL AMPLIFICATION - The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule. | 2013-02-07 |
20130034847 | OLIGONUCLEOTIDE BASED ANALYTE DETECTION METHOD - The invention relates to a method of detecting the presence of an analyte within a sample, wherein said method comprises an oligonucleotide based approach. The invention also relates to methods of diagnosing diseases, in particular, but not exclusively infectious diseases such as septicaemia. | 2013-02-07 |
20130034848 | TUMOR SUPPRESSOR GENE P33ING2 - The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods of diagnosing and treating tumors with such nucleic acids and proteins. | 2013-02-07 |
20130034849 | DIAGNOSIS OF HEREDITARY SPASTIC PARAPLEGIAS (HSP) BY DETECTION OF A MUTATION IN THE KIAA1840 GENE OR PROTEIN - The invention relates to an ex vivo method of diagnosing or predicting an hereditary spastic paraplegias (HSP), in a subject, which method comprises detecting a mutation in the KIAA1840 gene or protein (spatacsin), wherein said mutation is indicative of an hereditary spastic paraplegias (HSP). | 2013-02-07 |
20130034850 | MARKER FOR DETECTING MYOGENIC DISEASE AND DETECTION METHOD USING THE SAME - A marker for myogenic disease and a non-invasive, highly sensitive method for detecting the marker are presented. Analysis of blood levels of miR-1, miR-133a, miR-133b, and miR-206 in a subject is used to detect levels of the marker indicating myogenic disease. The method is independent of exercise-induced stress. | 2013-02-07 |
20130034851 | DETECTION OF METHYLATED DNA - The use of ion sensitive field effect transistor (ISFET) to detect methylated nucleotides in a DNA sample is described. A method of detecting methylated nucleotides in a DNA sample may include the steps of treating a sample of DNA with a reagent which discriminates between methylated and non-methylated nucleotides to provide treated DNA, amplifying the treated DNA and optionally sequencing the amplified DNA. An ISFET is used to monitor the addition of one or more dNTPs in the strand extension reactions during the amplification and/or sequencing step. Suitable apparatus is also provided. | 2013-02-07 |
20130034852 | METHOD FOR THE SELECTION OF A LONG-TERM PRODUCING CELL - Herein is reported a method for determining methylation of a promoter nucleic acid operably linked to a nucleic acid encoding a polypeptide and thereby determining the long-term productivity of a cell. Also an aspect is a method for selecting a cell for producing a polypeptide by determining the methylation of the promoter nucleic acid operably linked to the structural gene encoding the polypeptide. | 2013-02-07 |
20130034853 | TWO-COLOR CHROMOGENIC IN SITU HYBRIDIZATION - The present invention relates to systems and processes for chromogenic in situ hybridization (CISH), and in particular to methods that prevent interference between two or more color detection systems in a single assay. The present invention also relates to processes for scoring assays utilizing break-apart probes. | 2013-02-07 |
20130034854 | Antibody-Nanoparticle Conjugates and Methods for Making and Using Such Conjugates - Disclosed herein are antibody-nanoparticle conjugates that include two or more nanoparticles (such as gold, palladium, platinum, silver, copper, nickel, cobalt, iridium, or an alloy of two or more thereof) directly linked to an antibody or fragment thereof through a metal-thiol bond. Methods of making the antibody-nanoparticle conjugates disclosed herein include reacting an arylphosphine-nanoparticle composite with a reduced antibody to produce an antibody-nanoparticle conjugate. Also disclosed herein are methods for detecting a target molecule in a sample that include using an antibody-nanoparticle conjugate (such as the antibody-nanoparticle conjugates described herein) and kits for detecting target molecules utilizing the methods disclosed herein. | 2013-02-07 |
20130034855 | DETECTION OF MUTATIONS IN A GENE ENCODING IKB KINASE-COMPLEX-ASSOCIATED PROTEIN TO DIAGNOSE FAMILIAL DYSAUTONOMIA - A method for detecting the presence in a subject of a polymorphism linked to a gene associated with familial dysautonomia, said method comprising detecting a disruptive mutation in a gene of said subject encoding the IκB kinase-complex-associated protein, and, preferably, detecting a T→C change in position 6 of the donor splice site of intron 20 and/or a G→C transversion of nucleotide 2390 in exon 19 of the gene encoding the IκB kinase-complex-associated protein which is present on chromosome 9q31. Also disclosed are oligonucleotide primers useful in the detection method. This abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to ascertain quickly the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. | 2013-02-07 |
20130034856 | METHOD FOR DETECTING AND IDENTIFYING CANDIDA SPECIES - The present invention describes a method, based on a semi-nested polymerase chain reaction (PCR), for the detection and identification of ten clinically relevant | 2013-02-07 |
20130034857 | OPTICAL ANALYSIS APPARATUS AND OPTICAL ANALYSIS METHOD - Disclosed herein is an optical analysis apparatus including: a light source; a light guiding plate configured to guide incident light from the light source to each of reaction areas; a light shielding structure configured to restrict emission directions of light beams emitted from the inside of the reaction areas; and a detection system configured to detect the light beams emitted from the inside of the reaction areas by radiation of the light. | 2013-02-07 |
20130034858 | METHOD FOR DIAGNOSING A PROTEIN MISFOLDING DISEASE USING NERVE CELLS DERIVED FROM IPS CELLS - The present invention provides a method for detecting onset of, or the risk of development of, a protein misfolding disease, and a method for predicting the age of onset of a protein misfolding disease using nerve cells derived from iPS cells. The present invention also provides a kit to be used in these methods. | 2013-02-07 |
20130034859 | OPTICAL INSTRUMENT INCLUDING EXCITATION SOURCE - An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with an excitation beam generated by a light source. A collimating lens can be disposed along a beam path between the light source and the reaction regions to form bundles of collimated excitation beams, wherein each bundle corresponds to a respective reaction region. Methods of analysis using the optical instrument are also provided. | 2013-02-07 |
20130034860 | PRESERVATION OF CELL-FREE RNA IN BLOOD SAMPLES - A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids. | 2013-02-07 |
20130034861 | EARLY MARKER OF PROTEINURIA IN PATIENTS TREATED WITH AN ANTI-VEGF TREATMENT - This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided. | 2013-02-07 |
20130034862 | Methods for Diagnosis, Prognosis and Methods of Treatment - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 2013-02-07 |
20130034863 | Apparatus and Methods for Detecting Inflammation Using Quantum Dots - Apparatus and methods for detecting an a biomarker indicative of an inflammatory condition, including a capillary tube adapted for one or more biomarkers to adhere to an interior surface thereof, a light source for energizing quantum dots conjugated with the biomarkers within the capillary tube, and a detection system for detecting and quantifying fluorescent energy emitted by the quantum dots in one or more predetermined wavelength ranges, each wavelength range being correlated to one and only one of the biomarkers. A method of stabilizing the fluorescence intensity of quantum dots is also disclosed. | 2013-02-07 |
20130034864 | Protein, An Antibody and Measurement of the Protein - Methods for determining the occurrence or level of a mammalian protein in a sample and methods for determining the capability of a compound to transform or to inhibit the transformation of a selected mammalian protein in pro-phospholipase B form to an enzyme active phospholipase B form employ a pro-phospholipase B (PLB-II) mammalian protein which comprises at least one SU2 subunit comprising SEQ ID NO: 3 and having a molecular weight within the range of 30-60 kDa. Methods for determining the capability of a compound to enhance or inhibit the enzymatic activity of a selected protein having phospholipase B enzyme activity employ a protein comprising an activated form of such a pro-phospholipase B (PLB-II) mammalian protein. | 2013-02-07 |
20130034865 | CENTRIFUGAL FORCE-BASED MICROFLUIDIC DEVICE FOR MULTIPLXED ANALYSIS AND DETECTION METHOD USING THE SAME - A centrifugal force-based microfluidic device for a multiplexed analysis and an analyzing method using the same are provided. The microfluidic device includes a platform and a microfluidic structure including a plurality of chambers formed within the platform and valves positioned between the chambers. The microfluidic structure includes a sample separation chamber connected to a sample injection hole and a plurality of reaction chambers accommodating two or more types of markers specifically reacting to different types of target materials, separately by type. | 2013-02-07 |
20130034866 | MULTISIGNAL REAGENTS FOR LABELING ANALYTES - Provided is a composition comprising an analyte bound covalently or through a first binding pair to a polymer. In this composition, the analyte is less than about 2000 MW; the polymer further comprises more than one signal or first member of a second binding pair; and the analyte is not a member of the first binding pair or the second binding pair. Also provided is an assay for an analyte. The assay comprises: combining a sample suspected of containing the analyte with the above-described composition and a binding agent that binds to the analyte; and detecting the signal or the first member of the second binding pair that is bound to the binding agent. In this assay, the amount of the signal or the first member of the second binding pair bound to the binding agent is inversely proportional to the analyte in the sample. Additionally provided is a multisignal labeling reagent comprising a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule. | 2013-02-07 |
20130034867 | METHODS FOR ISOTOPICALLY LABELING BIOMOLECULES USING MAMMALIAN CELL-FREE EXTRACTS - Methods for producing an isotope-labeled mammalian, including a human, biomolecule, such as polypeptides and proteins, in a cell-free protein synthesis system. A biomolecule standard is produced having at least one isotope different in abundance than that of the naturally occurring isotopes in the biomolecule. Methods for quantifying biomolecules standards expressed using mammalian cell-free extracts are disclosed. Methods for producing such standards, kits, systems and reagents, relating to the use of isotope-labeled biomolecule as quantification standards in mass spectrometric and nuclear magnetic resonance analysis. | 2013-02-07 |
20130034868 | METHOD AND USE FOR ASSESSING RADIATION THERAPY IN ACCORDANCE WITH SAA - A method for assessing a subject to receive radiation therapy in accordance with the present invention includes the steps of obtaining a body fluid sample from the subject, measuring the concentration of serum amyloid A proteins of the body fluid sample and comparing the concentration of the serum amyloid A proteins with a range of values to determine whether the subject is suitable to receive radiation therapy. Additionally, the present invention also provides a use of serum amyloid A proteins for assessing whether a subject is suitable to receive radiation therapy. | 2013-02-07 |
20130034869 | DEVICES AND METHODS FOR MULTIPLEXED ASSAYS - The disclosure provides low cost, portable three-dimensional devices for performing multiplexed assays. The devices comprise at least two substantially planar layers disposed in parallel planes, wherein one of the layers is movable relative to each other parallel to the planes to permit the establishment of fluid flow communication serially between the two layers. | 2013-02-07 |
20130034870 | METHOD FOR BODILY FLUID SAMPLE TRANSFER DURING ANALYTE DETERMINATION - A method for the transfer of a bodily fluid sample (such as a whole blood sample) during the determination of an analyte (e.g., glucose) in the bodily fluid sample includes applying the bodily fluid sample to a sample collection reservoir of an analytical test strip (for example, an electrochemical-based analytical test strip). During such application, the sample collection reservoir is isolated from fluid communication with a determination chamber of the analytical test strip. The analytical test strip is subsequently inserted into a test meter such that the sample collection reservoir is placed into fluid communication with the determination chamber and such that at least a portion of the bodily fluid sample is consequentially transferred from the sample collection reservoir to the determination chamber. The method further includes determining the analyte in the bodily fluid sample transferred to the determination chamber. | 2013-02-07 |
20130034871 | HAND-HELD TEST METER AND ANALYTICAL TEST STRIP CARTRIDGE COMBINATION - A hand-held test meter and analytical test strip cartridge combination includes a hand-held test meter with a test meter housing and an extractor with a test strip engagement feature, while the analytical test strip cartridge includes a cartridge housing, a test strip presentation mechanism disposed within the cartridge housing, and a plurality of analytical test strips (each with at least one extractor engagement feature) disposed in the cartridge housing. Moreover, the test meter housing is configured for operative engagement with the cartridge housing, the test strip presentation mechanism is configured to present a single analytical test strip from the plurality of analytical test strips for engagement with the extractor, and the extractor and test meter housing are configured such that the extractor is operatively extendable from the test meter housing into the cartridge housing upon engagement of the meter housing with the cartridge housing. In addition, the extractor is also configured such that, upon operative extension, the extractor mechanically engages with the analytical test strip presented by the test strip presentation mechanism via engagement between the test strip engagement feature and the extractor engagement feature, and such that, upon disengagement of the test meter housing from the cartridge housing, the extractor removes the mechanically engaged analytical test strip from the cartridge housing and retracts into the test meter housing. | 2013-02-07 |
20130034872 | HAND-HELD TEST METER AND ANALYTICAL TEST STRIP CARTRIDGE ASSEMBLY WITH DESICCANT VIAL - A hand-held test meter and analytical test strip cartridge assembly combination includes a hand-held test meter with a test meter housing and an extractor with a test strip engagement feature, while the analytical test strip cartridge assembly includes a desiccant vial and an analytical test strip cartridge with a cartridge housing, a test strip presentation mechanism disposed within the cartridge housing, and a plurality of analytical test strips (each with at least one extractor engagement feature) disposed in the cartridge housing. The test meter housing is configured for operative engagement with the cartridge housing and the test strip presentation mechanism is configured to present a single analytical test strip from the plurality of analytical test strips for engagement with the extractor. Moreover, the analytical test strip cartridge is configured for operative disposition in the desiccant vial. | 2013-02-07 |
20130034873 | METHOD FOR THE EXTRACTION AND DETECTION OF FAT-SOLUBLE COMPONENTS FROM BIOLOGICAL MATERIALS - The present invention relates to a method for the analysis of fat-soluble components, in particular dyes, from biological materials, in particular lipid rich foodstuffs, having an enrichment of the components and subsequent analysis. The method comprises a combination of extraction and separation steps and a subsequent analysis step. The invention further relates to an analytical kit and analytical equipment for carrying out the method. The method according to the invention is composed of a plurality of steps. The critical steps which are essential and characterize the invention are: 1. Pre-treatment of the sample to remove lipids. 2. Extracting the dyes into an extraction mixture by a specific solvent or solvent mixture. 3. Destruction of the oxidative sensible ingredients such as carotenoids prior to the final detection and quantification by eye or by optical enhancement. | 2013-02-07 |
20130034874 | AUTOMATIC PROCESS AND AUTOMATED DEVICE FOR PREPARING AND ANALYSING A PLURALITY OF CELL SUSPENSIONS - The present invention relates to a process for preparing and analysing a plurality of cell suspensions ( | 2013-02-07 |
20130034875 | DNA CONSTRUCT, AND PROCESS FOR PRODUCTION OF RECOMBINANT CHO CELL USING SAME - Disclosed is a DNA construct that is useful for efficient generation of recombinant CHO cells useful for the production of target proteins. The DNA construct is a construct comprising, from a 5′ end toward a 3′ end, a first homologous DNA fragment, a target protein gene, and a second homologous DNA fragment. The first and second homologous DNA fragments have homology allowing for homologous recombination with a part of a hypoxanthine-phosphoribosyltransferase enzyme (hprt) locus in a CHO cell genome and have a chain length of not less than 1 kbp. | 2013-02-07 |
20130034876 | Systems and Methods to Increase Protein Yield from Recombinant Manufacturing Processes - Embodiments disclosed herein provide systems and methods that increase protein yield from recombinant manufacturing processes. The systems and methods treat used depth filters with bound proteins of interest as a stationary phase exchange resin to recapture bound protein of interest from the depth filter. | 2013-02-07 |
20130034877 | METHOD FOR INCREASING THERMAL STABILITY AND RETAINING ACTIVITY OF A PROTEIN - The present invention provides a method and a system for increasing thermal stability of a starch binding protein (SBP)-tagged recombinant protein. The present invention also provides a method for preventing releasing a SBP-tagged recombinant protein from a SBP-binding matrix and retaining an activity of the recombinant protein in aquatic environment. | 2013-02-07 |
20130034878 | Chondroitin Synthase, Method for Producing The Same and Method for Producing Saccharide Chain-Extended Chondroitin - A vector of the present invention has DNA encoding a protein or a product having the same effect as the protein, the protein containing an amino acid sequence from amino acid numbers 47 to 802 in SEQ. ID. NO:2. Expression of the DNA gives human chondroitin synthase. By using human chondroitin synthase, it is possible to produce a saccharide chain having a repeating disaccharide unit of chondroitin. The DNA or part thereof may be used as a probe for hybridization for the human chondroitin synthase. | 2013-02-07 |
20130034879 | DNA Polymerases - A DNA polymerase mutant comprising a Taq DNA polymerase amino acid sequence with a mutation at one or more of the following selected amino acid positions: E189K, E230K, E507K, H28R, L30R, G38R, F73V, H75R, E76A, E76G, E76K, E90K, K206R, E315K, A348V, L351F, A439T, D452N, G504S, E507A, D551N, L552R, I553V, D578N, H676R, Q680R, D732G, E734G, E734K, F749V; wherein the polymerase mutant exhibits relative to wild-type DNA polymerase increased polymerase speed, increased affinity to DNA substrate and/or increased resistance to a DNA polymerase inhibitor; and wherein, when the mutation is E507K in combination with two or more further mutations or the mutation is Q680R in combination with four or more further mutations, at least one of the further mutations is at one of the selected amino acid positions; and when the mutation is I553V, this is not in combination with D551S. | 2013-02-07 |
20130034880 | CHAMBER FREE NANOREACTOR SYSTEM - Aspects of the invention include methods for improving the accuracy and read length of sequencing reactions by utilizing unlabeled unincorporable nucleotides, or by rephasing colony based sequencing reactions. Other aspects include systems and devices for improved measurement of biological reactions associated with bead which may be removed, utilizing current measurement methods through the counter ions associated with said beads due to the presence of reactants bound or associated with said bead, wherein electrodes for generating and measuring said current may be within the Debye length of said bead. Other aspects of the invention include methods for determining concentrations of input samples, means for reuse of an array, methods and apparatus for separating beads with different charge levels from each other. | 2013-02-07 |
20130034881 | MOLECULES AND METHODS FOR DEMETHYLATION OF METHYLATED NUCLEIC ACID SEQUENCES - Demethylation of a methylated DNA sequence in a eukaryotic cell is described, utilising a molecule that includes at least a first domain that exhibits a cytidine deaminase activity and at least a second domain that confers either a specific or non-specific DNA binding activity. The molecules of the invention are useful in somatic cell nuclear transfer and also in cancer therapy | 2013-02-07 |
20130034882 | MINICIRCLE DNA VECTOR PREPARATIONS AND METHODS OF MAKING AND USING THE SAME - The present invention provides minicircle nucleic acid vector formulations for use in administering to a subject, wherein the minicircle nucleic acid vectors include a polynucleotide of interest, a product hybrid sequence of a unidirectional site-specific recombinase, and are devoid of plasmid backbone bacterial DNA sequences. Also provided are methods of producing the subject formulations as well as methods for administering the minicircle nucleic acid vector formulations to a subject. The subject methods and compositions find use in a variety of different applications, including both research and therapeutic applications. | 2013-02-07 |
20130034883 | Processes of Producing a Fermentation Product - The invention relates to a process of process of producing a fermentation product, comprising: liquefying a starch-containing material to dextrins with an alpha-amylase in the presence of a GH61 polypeptide; saccharifying the dextrins to a sugar with a glucoamylase; and fermenting the sugar using a fermenting organism. | 2013-02-07 |
20130034884 | MICROORGANISMS FOR PRODUCING 1,4-BUTANEDIOL AND METHODS RELATED THERETO - The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO), 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway comprising at least one exogenous nucleic acid encoding a BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway enzyme expressed in a sufficient amount to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine. | 2013-02-07 |
20130034885 | PROCESS FOR THE ENZYMATIC PRODUCTION OF CARNITINE FROM BETA-LACTONES - Subject of the invention is a process for the production of L-carnitine, wherein a β-lactone, which is a 4-(halomethyl)oxetane-2-one, is converted into L-carnitine, wherein the process comprises an enzymatic conversion of the β-lactone into (R)-4-halo-3-hydroxybutyric acid or (R)-4-halo-3-hydroxybutyric acid ester. | 2013-02-07 |
20130034886 | PSEUDOMONAS AERUGINOSA STRAIN DEVELOPED FOR IMPROVING FATTY ACID CONTENT, AND METHOD OF MANUFACTURING THE SAME - Disclosed are novel | 2013-02-07 |
20130034887 | Tailored Oils Produced from Recombinant Oleaginous Microorganisms - Methods and compositions for the production of oil, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty acid hydroxylase, a desaturase enzyme, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants. | 2013-02-07 |
20130034888 | METHODS AND COMPOSITIONS FOR DECOMPOSITION OF BIOMASS - Disclosed are methods for detecting cellulose in cellulosic materials and producing alcohol using cellulosic materials. More particularly, disclosed are methods for producing alcohol in a cell-free system by contacting pyruvate with enzymes from a minimal enzymatic pathway. Also disclosed are methods of producing pyruvate by culturing a microorganism under hypoxic conditions. Disclosed are methods for detecting cellulose in a sample using Congo red dye. | 2013-02-07 |
20130034889 | NOVEL MICROORGANISM, AND HYDROGEN PRODUCTION PROCESS, 1,3-PROPANEDIOL PRODUCTION PROCESS AND BIODIESEL LIQUID WASTE TREATMENT METHOD EACH USING THE MICROORGANISM - The present invention provides a microorganism belonging to the genus | 2013-02-07 |
20130034890 | Polypeptides Having Cellobiohydrolase 1 Activity and Polynucleotides Encoding Same - The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides. | 2013-02-07 |
20130034891 | CONVERSION METHOD - A process is described for the preparation of water-soluble cellulose hydrolysis product. The process comprise admixing cellulose with an ionic liquid capable of solvating or dissolving at least some of the cellulose, said ionic liquid being a compound comprises solely of cations and anions and which exists in a liquid state at a temperature at or below 150° C., and in which the anions are selected from halide and cyanate; and treating the resulting solvate or solution with an acid in the presence of water, said acid having a pKa in water of less than 2 at 25° C. | 2013-02-07 |
20130034892 | METHOD FOR THE PRODUCTION OF A FERMENTED NATURAL PRODUCT - What is described is a process for producing a fermented natural product, wherein several ferment extracts are produced from raw materials of the natural product and admixed with a propagate from microorganisms. Also described is a plant for performing the process. | 2013-02-07 |
20130034893 | Methods for Coupling of Molecules to Metal/Metal Oxide Surfaces - Functionalized magnetic particles are emerging as a reliable and convenient technique in the purification of biomacromolecules (proteins and nucleic acids). We disclose a novel coupling procedure that can be used to create stable ferromagnetic nickel particles coated with Protein A for the affinity purification of antibody. The protein purification procedure is gentle, scalable, automatable, efficient and economical. By modifying the functional groups of amino acids in the protein coating, nickel particles can be used not only for affinity purification but for other sample preparation and chromatographic applications as well including nucleic acid isolations. The method can be easily modified for small and medium scale antibody purification in lab and pre-clinical research. | 2013-02-07 |
20130034894 | NOVEL ALLENE OXIDE SYNTHASE DERIVED FROM LEMNA PAUCICOSTATA - A highly active allene oxide synthase that can be used in the production of a plant growth regulating agent (KODA) is provided. | 2013-02-07 |
20130034895 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF AZETIDINONE - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 2013-02-07 |