05th week of 2009 patent applcation highlights part 48 |
Patent application number | Title | Published |
20090029818 | Flat transmission belt - There is provided a flat transmission belt that suppresses occurrence of cracks in the belt surfaces to extend the life of cover rubber layers and hence the life of the belt as a whole. A flat transmission belt of the present invention has a first cover rubber layer and a second cover rubber layer formed on a side of the belt opposite to the side on which the first cover rubber layer is formed, and is wound between driving and driven pulleys when in use. The first cover rubber layer and the second cover rubber layer are respectively formed of rubber materials that are of the same kind but differ in mixing ratio of the components thereof, and the first cover rubber layer, which contacts a smaller number of the driving and driven pulleys, has an extension ratio higher than the extension ratio of the second cover rubber layer, which contacts a larger number of the driving and driven pulleys. | 2009-01-29 |
20090029819 | CONTROLLER OF DRIVING DEVICE FOR VEHICLE - A transmission mechanism including a switching clutch or brake that is switchable between a continuously-variable shifting state and a step-variable shifting state, and has both an advantage of improved fuel economy provided by a transmission, the speed ratio of which is electrically variable, and an advantage of high power transmitting efficiency provided by a gear type power transmitting device constructed for mechanical transmission of power. While a clutch-to-clutch shifting action of an automatic transmission portion is in a tie-up state, a differential portion is placed in a continuously-variable shifting state by switching control, and engine speed is changed under the control of hybrid control, so as to prevent a drop of the engine speed for thereby reducing a shock of the shifting action, unlike in a non-continuously-variable shifting state of the differential portion in which the engine speed is directly influenced by the tie-up state. | 2009-01-29 |
20090029820 | Lubricating oil supply device for automatic transmission - In a lubricating oil supply device for an automatic transmission which supplies lubricating oil to a clutch arranged inside an automatic transmission, an oil reception section in a circumferential direction which receives the lubricating oil and is open in a shaft direction of an input shaft is formed in an approximately annular-shaped carrier cover by a wall section of the carrier cover which, together with a carrier, attaches a pinion shaft, a base section of the carrier cover extending in the shaft direction of the pinion shaft, and an end section as a part in an inner direction of the clutch hub connected with the base section of the carrier cover. | 2009-01-29 |
20090029821 | CARRIER ASSEMBLY - A carrier assembly has a unique architecture which allows the carrier assembly to be defined by a very small packaging envelope. The carrier includes a main carrier housing with an internal cavity for receiving a differential and a carrier cover that closes the internal cavity once the differential has been installed. Examples of architectural features include a differential lock actuator that is mounted to the carrier cover, dowel pins that accommodate differential leg thrust loads and align the carrier cover relative to the main carrier housing, and bolt-in differential leg structures to facilitate pinion installation. Further, the carrier assembly can be utilized with an independent suspension to provide a increased jounce travel range. | 2009-01-29 |
20090029822 | Multi-stage automatic gearbox - A multi-speed automatic transmission comprises a drive input shaft (AN), a drive output shaft (AB), a double planetary transfer gearset (VS), a main gearset (HS) made as a coupled planetary gearset with at least three non-coupled input elements and one output element, and six shift elements (A to F), which, when engaged in pairs, enable at least eight forward gears to be engaged. An input element of the transfer gearset (VS) is connected with the drive input shaft (AN). An output element of the transfer gearset (VS) rotates at a speed slower than the input speed of the drive input shaft (AN). An element of the transfer gearset (VS) is fixed on a transmission housing (GG). The first input element of the main gearset (HS) can be connected via a second shift element (B) to the output element of the transfer gearset (VS), can be fixed by a third shift element (C), and can be connected with the drive input shaft (AN) by a sixth shift element (F). The second input element of the main gearset (HS) can be connected via a first shift element (A) to the output element of the transfer gearset (VS). The third input element of the main gearset (HS) can be fixed by a fourth shift element (D) and can be connected by a fifth shift element (E) to the drive input shaft (AN). The output element of the main gearset (HS) is connected to the drive output shaft (AB). The sixth shift element (F) is arranged axially between the transfer and main gearsets (VS, HS). A servomechanism ( | 2009-01-29 |
20090029823 | Hybrid Vehicle - In a hybrid vehicle having at least one electric motor which is usable as a generator and charges a vehicle battery during a recuperation phase, there is provided an additional actuating element independent of a brake system which is used to transfer the electric motor into its recuperation state without activating the brake system. Alternatively, the additional actuating element may operate in conjunction with the brake system, such that the brake pedal may also be used to transfer the electric motor into its recuperation state. | 2009-01-29 |
20090029824 | Drive apparatus for vehicle - A drive apparatus for vehicle, available to be minimized, is provided. A first planetary gear set (differential device) | 2009-01-29 |
20090029825 | Control device for vehicular power transmitting device - This invention relates to a control device for a vehicular power transmitting device. The control device has shifting-point altering means | 2009-01-29 |
20090029826 | Controller of work vehicle - Various works of a tractor or wheel loader that require frequent operations of start, stop, and switching between the forward drive and reverse drive that are repeated alternately can be performed very easily. The control apparatus comprises a speed change sensor that detects the step-on amount of a speed change pedal, an actuator that regulates the swash plate angle of a hydraulic pump based on the detection value of the speed change sensor, a transmission output unit rotation sensor that detects the revolution speed of an output shaft, and a control unit. The control unit performs control such that when the speed change pedal is not stepped on, a brake is applied to the travel wheels and both the forward drive clutch and the reverse drive clutch are disengaged, and also performs control such that when the transmission drive output detected with the transmission output unit rotation sensor is not more than that the forward-reverse drive switching speed, either the forward drive clutch or the reverse drive clutch is engaged as the speed change pedal is stepped on. When the engagement of the forward drive clutch or reverse drive clutch is confirmed, the brake of the travel wheels is released. | 2009-01-29 |
20090029827 | Method and apparatus for controlling transmission functions in a vehicle transmission - A method and apparatus for controlling transmission functions in a transmission of a motor vehicle by an electromagnetically actuated control valve. The control valve is controlled by a control device that includes a stored valve characteristic curve to provide a temperature-dependent and a target-current-dependent overlay, so that a symmetrical target value oscillation around a target current value is achieved. The characteristic curve for controlling the control valve is adapted at least partially as a function of a current value and a temperature. | 2009-01-29 |
20090029828 | Vehicle's Active Electrically Controlled Non-Step Speed Change Mechanism - A vehicle's active electrically controlled non-step speed change mechanism includes an internal combustion engine, a dynamo (motor-generator), a power allotment unit and an active electrically controlled non-step speed changer to control vehicle able to run in the best condition notwithstanding its speed, roadway condition or load thereby achieving the aim of fuel saving and minimizing the environmental contamination due to excess discharge of exhaust gas. | 2009-01-29 |
20090029829 | NOSE TO BACK NECK AND EYE MUSCLES EXERCISE - A nose to back neck and eye muscles exercise for improved facial enhancement, resulting in a more youthful appearance because of reduced or eliminated wrinkling of the face, is one representation of this invention. This exercise affects all of the facial muscle area beginning at the nose and going upward, ending at the back of the neck area. Notable improvement results in a tightened, smaller slenderized nose and reduced or eliminated wrinkling around facial eye area and forehead. Not only is a more youthful appearance achieved, but eyesight (vision) is greatly improved from strengthened supportive facial muscles surrounding eyes and independently strengthened muscles of the eyes as a result of this exercise. It is not possible to receive one natural benefit of the muscles exercise of this present invention of reduced wrinkling and a more youthful appearance without receiving its naturally intertwined second benefit of improved eyesight, and vice versa. | 2009-01-29 |
20090029830 | Grip strengthener with therapy ball - A grip strengthener with therapy ball includes a resilient pad and ball. The pad is flat and has at least one side surface, a top surface, a bottom surface, a ball mount and a finger slit. The ball mount is defined through the pad and has an inner edge. The finger slit is defined in the top surface of the pad between the ball mount and one of the at least one side surface. The ball is mounted detachably in the ball mount of the pad and has an outer surface, a mounting groove, a top side and a bottom side. The mounting groove is defined around the outer surface of the ball and engages the inner edge of the ball mount in the pad. The top side and the bottom side respectively protrude the top surface and the bottom surface of the pad. | 2009-01-29 |
20090029831 | DEVICE AND METHOD FOR LIMITING TRAVEL IN AN EXERCISE DEVICE, AND AN EXERCISE DEVICE INCLUDING SUCH A LIMITING DEVICE - A method and/or a device may limit a distance traveled by a treadle assembly in an exercise device. For example, the distance traveled by the treadle assembly may be limited by limiting a distance that a resistance element operably coupled to the treadle assembly may travel. An exercise apparatus may include a travel-limiting device or capability. | 2009-01-29 |
20090029832 | Balanced magnetic brake assembly for exercise cycling apparatus - A brake assembly for exercise cycling apparatus comprises rotor means ( | 2009-01-29 |
20090029833 | EXERCISING BALL - An exercising ball includes an inflatable ball body made of an elastic material and defining a chamber, and a moving element disposed movably in the chamber. The inflatable ball body has a passage hole that permits the moving element to enter the chamber, and an inflation valve fitted sealingly and removably in the passage hole. | 2009-01-29 |
20090029834 | SQUAT MACHINE FOR EXERCISING - The squat machine of the present invention includes a base having opposite sides, a stationary foot plate fixed on the base, a pair of frames each pivotally mounted to respective sides of the base, and a back rest pivotally mounted to the frames so that the frames and back rests are moveable between an initial squat position and an extended position. The back rest is oriented at approximately a 45°-60° angle in the squat position and moves toward a substantially horizontal orientation in the extended position. In use, with proportional foot platement on the foot plate, the user's knees remain behind their toes throughout full range of motion through the hips during movement of the back rest so as to minimize risk of knee shear. The orientation of the back rest minimizes risk of spinal compression during use of the machine. | 2009-01-29 |
20090029835 | MOMENT ARM WEIGHT RESISTANCE MECHANISM AND WEIGHT TRAINING MACHINES UTILIZING THE SAME - A weight training machine having a moment arm weight resistance means for creating a weight resistance or weight load. | 2009-01-29 |
20090029836 | AUTOMATIC FEED-THROUGH SHAPE AND SAND MACHINE - A method and apparatus for quickly changing CNC machine tools is presented. Tool changes of 40 seconds or less are possible. A tool repository of linearly spaced apart tool forks translates to a storage position for CNC machining operations. For tool changing, the tool repository translates to a staging location, where an existing tool may be deposited to an empty location in the tool repository, whereupon another tool may be selected and engaged on the CNC machining spindle. The tool repository retracts to a storage position, and CNC machining operations may continue. This design may be used for CNC machines with many additional axes of operation, and appears more compact, less expensive, more robust, and lighter that traditional turret carousel designs. Stacked tools 5 inches high and diameters of 8 inches may be used in one embodiment. In the same space 15 smaller tools of 1.5 inch diameter may be stored. | 2009-01-29 |
20090029837 | STITCH FLAP CUTTING BLOCK - A stitch flap cutting block is mountable to a cutting head of a board blank cutting machine, along with a slotting knife. A sheet of board passed between the cutting head and an anvil head is cut to form a blank for a box or the like. The cutting block comprises a steel body with a cylindrical barrel holding a cylindrical spring block, to which is mounted a blade holder carrying an elongate blade. The blade moves within a transverse slot across the body and is deflectable into the body and may rock about a midpoint of the slot. Impact forces are reduced, cleaner cuts are produced, and re-setting of the blade is required much less often. An alternative stitch flap cutting block is mountable to the cutting head by a separate side arm, facilitating mounting cutting to heads having different diameters. | 2009-01-29 |
20090029838 | Patterning Technology for Folded Sheet Structures - The present invention supplies practical procedures, functions or techniques for folding tessellations. Several tessellation crease pattern techniques, and the three-dimensional folded configuration are given. Additionally several new forming processes, including mathematical methods for describing the material flow are disclosed doubly-periodic folding of materials that name the doubly-periodic folded (DPF) surface, including vertices, edges, and facets, at any stage of the folding. This information is necessary for designing tooling and forming equipment, for analyzing strength and deflections of the DPFs under a variety of conditions, for modeling the physical properties of DPF laminations and composite structures, for understanding the acoustic or other wave absorption/diffusion/reflection characteristics, and for analyzing and optimizing the structure of DPFs in any other physical situation. Fundamental methods and procedures for designing and generating DPF materials include ways for defining the tessellation crease patterns, the folding process, and the three-dimensional folded configuration. The ways are mathematically sound in that they can be extended to a theorem/proof format. | 2009-01-29 |
20090029839 | Soft Roll Material-Translation Device - The present invention relates to a soft roll material-translating device for the mechanical apparatus of machining and cutting after severing. The existing pillow type of automatic packing machine can only pack produces using one single roll of film, so the work efficiency is low. Consequently, the present invention aims at improving the work efficiency and it adopts following technical solutions: the soft roll material-translating device includes a frame ( | 2009-01-29 |
20090029840 | CORRUGATING MACHINE - A corrugating machine includes a bed, a first rolling mechanism arranged on one side of the bed and including a plurality of longitudinal flute forming roll sets; and a second rolling mechanism arranged on another side of the bed and including a corrugating roll, a transverse flute forming roll and a toothed roll respectively located at an upper and a lower position at one side of the corrugating roll to mesh with the corrugating roll, a glue spraying unit located between the corrugating roll and the transverse flute forming roll, and a smooth roll and an adhesive dispensing unit respectively located at an upper and a lower position at another side of the corrugating roll. At least three plies of work material may be rolled, fluted, embossed, and bonded together using the two rolling mechanisms to thereby provide enhanced structural strength and improved damping effect. | 2009-01-29 |
20090029841 | Glassware Breaking Apparatus - A glassware-breaking machine can be used to reduce the volume of glass waste and also to reduce disposal costs. The machine can be provided with a plurality of flaps to reduce noise. In order to reduce the risk of glassware becoming jammed, a conduit can be provided with an internal cross section that increases in size in a direction towards a glassware breaking device. The glassware-breaking device may be rotatably mounted within the machine and may have a container underneath it for collecting broken glass. The machine can be of compact construction. It allows noise levels to be reduced significantly, relative to known industrial glassware-breaking machines | 2009-01-29 |
20090029842 | Fused silica having low OH, OD levels and method of making - A fused silica article having a combined concentration of hydroxyl (OH) and deuteroxyl (OD) concentration of less than 10 parts per million (ppm) and, in one embodiment, less than 1 ppm. The fused silica article is formed by drying a soot blank in a halogen-free atmosphere comprising carbon monoxide. The dried soot blank may optionally be doped to reach target levels of OH and OD concentrations and improve homogeneity within the fused silica article. The dried soot blank is then oxidized and, sintered to form the article. A method of reducing the combined concentration of OH and OD to less than 10 ppm is also described. | 2009-01-29 |
20090029843 | High-volume, fully dense silicon nitride monolith and method of making by simultaneously joing and hot pressing a plurality of RBSN parts - High-volume, fully dense, multi-component monoliths with microstructurally indistinguishable joints that can be used as refractory, corrosion and wear resistant components in the non-ferrous metal industry. The Si | 2009-01-29 |
20090029844 | Rare-earth oxide sintered body and manufacturing method - A rare-earth oxide sintered body, or corrosion-resistant material, having low sintering temperature and high density is prepared by adding a boron compound at a ratio of 0.06 mol % or more and less than 25 mol % when converted into boron oxide (B | 2009-01-29 |
20090029845 | FAU-structural-type supported zeolite membranes, their process for preparation and their applications - The invention relates to a FAU-type zeolite membrane that comprises a FAU-type zeolite crystal layer incorporated in the surface porosity of at least one selected face of a porous substrate, in which the ratio between the thickness of said zeolite layer incorporated in the surface porosity of said selected face of the substrate and the total thickness of said zeolite layer is at least 70%. It also relates to processes for preparation and application of these membranes. | 2009-01-29 |
20090029846 | HF alkylation process with acid regeneration - The regeneration of HF alkylation acid in an alkylation unit is improved by withdrawing a vapor stream from the HF regenerator tower and condensing the stream to form a liquid fraction which is accumulated in a side distillation zone; the collected liquid fraction, comprising HF acid, water and some stripping medium is distilled in a batch or continuous type operation to drive off the HF acid (along with stripping medium) and the vapor is returned to the regenerator-stripper vessel. The distillation of the sidedraw liquid is continued until the composition of the liquid attains the azeotropic value or as near to that value as desired. The azeotrope, comprising water and acid can then be dropped out of the distillation vessel for disposal by neutralization in the conventional way. | 2009-01-29 |
20090029847 | Mesostructured material with a high aluminium content - A mesostructured material that consists of at least two elementary spherical particles, each of said particles comprising a mesostructured matrix based on aluminum oxide and having a pore size of between 1.5 and 30 nm, an aluminum oxide content that represents more than 46% by weight relative to the mass of said matrix, which has amorphous walls with a thickness of between 1 and 30 nm and whereby said elementary spherical particles have a maximum diameter of 10 μm, is described. Said mesostructured matrix can also contain silicon oxide. Each of the spherical particles of the mesostructured material can also contain zeolitic nanocrystals so as to form a material with a mixed porosity that is both mesostructured and zeolitic in nature. The preparation of said material is also described. | 2009-01-29 |
20090029848 | Process for Producing Microparticulate Hardening Catalyst - A process for producing a microparticulate hardening catalyst, comprising the steps of jetting a liquid composition containing epoxy resin hardening catalyst (A), monomer having an ethylenically unsaturated group (B) and photopolymerization initiator (C) through a minute nozzle into a gas so as to form microparticles; and while the microparticles are floating, irradiating the same with high-energy rays to thereby effect polymerization of the monomer having an ethylenically unsaturated group (B). | 2009-01-29 |
20090029849 | IMMOBILIZED HOMOGENEOUS CATALYSTS - A catalyst is produced by bonding a homogeneous catalyst to the surface of a catalyst support. A catalyst may include a catalyst support, a spacer molecule bonded to the catalyst support, and a homogeneous catalyst bonded to the spacer molecule. A catalyzed reaction can be carried out by providing reactants in a first phase and providing a catalyst as described herein in the first phase. | 2009-01-29 |
20090029850 | Method for Preparing a Catalyst for Dehydrogenation of Cyclohexanol - A copper oxide based catalyst for dehydrogenation of cyclohexanol which is a copper oxide-zinc oxide based catalyst or a copper oxide-silicon oxide based catalyst further comprising one of palladium, platinum and ruthenium in a very small amount; and a method for preparing the copper oxide based catalyst which comprises combining the co-precipitation method or the kneading method and the spray method. The copper oxide based catalyst for dehydrogenation of cyclohexanol exhibits high activity and high selectivity, and thus may be used for producing cyclohexanone at a reduced reaction temperature and/or with an enhanced yield, as compared to a conventional catalyst. | 2009-01-29 |
20090029851 | Method For Producing Heat-Resisting Compound Oxides - A method for producing a heat-resisting compound oxide in which oxide particles are made to carry fine particles having a smaller particle diameter than that of said oxide particles. Said oxide particles or their precursor particles are charged to a potential inverse to that of said fine particles or their precursor particles so that said oxide particles adsorb said fine particles, and are then sintered to carry said fine particles. Thus, the fine particles can be homogeneously dispersed and firmly adhered to the surfaces of the oxide particles. As a result, the compound oxide is so excellent in heat resistance that it has little change, even subjected to a treatment such as a sintering, in the structure of the oxide particles for a carrier or in the adsorption state of the ultrafine particles, and has little thermal deterioration. | 2009-01-29 |
20090029852 | Molybdenum Compositions And Methods of Making the Same - The present invention is directed to molybdenum compositions and methods for making such metal oxide compositions, specifically, such compositions having high surface area, high metal/metal oxide content, and/or thermal stability with inexpensive and easy to handle materials. | 2009-01-29 |
20090029853 | Adsorbent and Process for Producing the Same - [Problems] To provide an adsorbent that is low in the drop of lower aliphatic aldehyde adsorbing capacity over time during storage thereof, and provide a process for producing the same. | 2009-01-29 |
20090029854 | REVERSIBLE THERMOSENSITIVE RECORDING MATERIAL, IC CARD, MAGNETIC CARD AND METHOD FOR PRODUCING REVERSIBLE THERMOSENSITIVE RECORDING MATERIAL - A reversible thermosensitive recording material including a support, a reversible thermosensitive recording layer, and a gas barrier layer, the reversible thermosensitive recording layer and gas barrier layer being laid over the support, wherein the reversible thermosensitive recording layer is formed of a reversible thermosensitive composition containing a mixture of an electron-accepting compound and an electron-donating color-forming compound whose color-developed state varies depending upon at least one of a heating temperature and a cooling rate after heating, and wherein the gas barrier layer contains an inorganic layered compound and a gas barrier resin which is at least one selected from the group consisting of polyvinyl alcohol polymers and ethylene-vinyl alcohol copolymers. | 2009-01-29 |
20090029855 | Quinoline Derivatives and Their Use as Pesticides - This invention relates to quinoline derivatives of formula I | 2009-01-29 |
20090029856 | Hinokitiol As A Plant Pesticide - The present invention discloses that a natural tropolone compound, hinokitiol, also known as β-Thujaplicin as an effective biopesticide for use in controlling plant pests. In particular, hinokitiol and/or salts thereof may be used in modulating non-Erwinia plant microbial infection or in the formulation of a non-Erwinia antimicrobial agent. Alternatively, hinokitiol may be used as a natural herbicide to control the germination and growth of weeds. The formulation used in the present invention may contain a chelator, pH adjustor and UV protection agent in an amount effective to stabilize said hinokitiol. | 2009-01-29 |
20090029857 | Synergistic Herbicidal Compositions - Synergistic compositions are described, having a high herbicidal activity and containing the compound having formula (I): in a mixture with one or more known herbicidal products. | 2009-01-29 |
20090029858 | Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids - The invention relates to novel spirocyclic 3′-alkoxytetramic acids and -tetronic acids of the formula (I), | 2009-01-29 |
20090029859 | WHEAT PLANTS HAVING INCREASED RESISTANCE TO IMIDAZOLINONE HERBICIDES - The present invention is directed to plants having increased resistance to an imidazolinone herbicide. More particularly, the present invention includes wheat plants and triticale plants containing at least one IMI nucleic acid such as an imidazolinone resistant Brookton BR-8 or Krichauff K-42 cultivar. The present invention also includes seeds produced by these wheat plants and triticale plants and methods of controlling weeds in the vicinity of these wheat plants. | 2009-01-29 |
20090029860 | NOVEL MUTATION INVOLVED IN INCREASED TOLERANCE TO IMIDAZOLINONE HERBICIDES IN PLANTS - The present invention is directed to nucleic acids encoding polypeptides that confer upon a plant tolerance to an imidazolinone and/or other acetohydroxyacid synthase (AHAS) inhibiting herbicide when expressed in the plant. The present invention also provides plants having increased tolerance to an imidazolinone and/or other AHAS-inhibiting herbicide. More particularly, the present invention includes plants containing at least one IMI nucleic acid. The present invention also includes seeds produced by these plants and methods of controlling weeds in the vicinity of these wheat plants. | 2009-01-29 |
20090029861 | CHLOROPLAST TRANSIT PEPTIDES FOR EFFICIENT TARGETING OF DMO AND USES THEREOF - The invention provides for identification and use of certain chloroplast transit peptides for efficient processing and localization of dicamba monooxygenase (DMO) enzyme in transgenic plants. Methods for producing dicamba tolerant plants, methods for controlling weed growth, and methods for producing food, feed, and other products are also provided, as well as seed that confers tolerance to dicamba when it is applied pre- or post-emergence. | 2009-01-29 |
20090029862 | HERBICIDAL SUSPENSION - A herbicidal suspension comprising (1) a sulfonylurea compound or its salt as a herbicidal component, (2) at least one surfactant selected from the group consisting of an alkoxylated sorbitol fatty acid ester and an alkoxylated sorbitan fatty acid ester, and (3) a water-immiscible diluent. A method for controlling undesired plants or inhibiting their growth, which comprises applying a herbicidally effective amount of the herbicidal suspension to the undesired plants or to a place where they grow. | 2009-01-29 |
20090029863 | PESTICIDES AND USES THEREOF - The invention disclosed in this document is related to field of pesticides and their use in controlling pests. In particular compounds having the following formula are disclosed. | 2009-01-29 |
20090029864 | Method For Screening Toxin Neutralizing Peptide, STX2 Inhibiting Peptide And Verotoxin Neutralizing Agent - A screening method comprises the following steps;
| 2009-01-29 |
20090029865 | IDENTIFICATION OF MOLECULAR SEQUENCE SIGNATURES AND METHODS INVOLVING THE SAME - Novel means and methods for analyzing hybridization data derived from hybridization assays between a target nucleic acid and differently sequenced polynucleotide probes involve selecting probe sets that define reference sequences for sequence signatures and deriving useful data about the nature of the target nucleic acid molecule based on its hybridization to the probes. The methods are useful for determining whether the target contains a nucleic acid or polypeptide sequence signature, whether the target encodes a member of a gene family, or whether the target is derived from one of any number of genes. | 2009-01-29 |
20090029866 | Libraries of oligomers labeled with different tags - A method of making a set of labelled compounds by the use of a preferably particulate support, comprises dividing the support into lots, performing a different chemical reaction on each lot of the support, e.g. to couple a chemical moiety to that lot of the support, tagging a fraction of each lot of the support with a different label, and combining the said lots of the support. The steps are repeated several times, preferably to build up oligomer molecules carrying labels which identify the nature and position of a monomer unit of the oligomer, and which are releasable from the support. Preferred labels, which are releasable from the compounds by cleavage to provide charged groups for analysis by mass spectrometry, are groups of the trityl (trimethylphenyl) family. Also claimed are libraries of these labels and their use in assays and nucleic acid analysis methods. | 2009-01-29 |
20090029867 | DNA purification and analysis on nanoengineered surfaces - A microfluidic device for isolating genomic DNA from human leukocytes, simultaneously capturing and measuring the DNA for simplifying genetic analysis. The device contains a fluid inlet port, a fluid outlet port, and a DNA binding channel in contact with the fluid inlet port wherein at least a portion of at least one surface within the DNA binding channel is modified with a binding reagent such that DNA is preferentially bound to the surface. | 2009-01-29 |
20090029868 | Expression signature in peripheral blood for detection of aortic aneurysm - We hypothesized that gene expression patterns in peripheral blood cells may correlate with TAA disease status, and carried out a comprehensive gene expression survey on peripheral blood cells obtained from TAA patients and normal individuals. A distinct gene expression profile in peripheral blood cells can classify TAA patients from normal individuals. The genes provided by the present teachings define a set of diagnostic markers, thus providing a blood-based gene expression test to facilitate early detection of TAA disease. Methods of distinguishing ascending from descending TAA are also provided, as are methods of distinguishing familial from sporadic TAA. | 2009-01-29 |
20090029869 | SURFACE MODIFICATION, LINKER ATTACHMENT, AND POLYMERIZATION METHODS - The present invention relates to surface modifications and linker attachments. For example, the present invention provides surface modification and linker chemistry that facilitates manufacture and use of microarrays, including nucleic acid and protein microarrays. The present invention also relates to array spotting through non-aqueous liquids. | 2009-01-29 |
20090029870 | Particle Analyzing Systems and Methods Using Acoustic Radiation Pressure - The present invention comprises methods and systems that use acoustic radiation pressure. | 2009-01-29 |
20090029871 | METHOD FOR SIMULTANEOUSLY PERFORMING MULTIPLE AMPLIFICATION REACTIONS - An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step. | 2009-01-29 |
20090029872 | Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof - This invention provides a genetically tractable in situ non-human animal model for hepatocellular carcinoma. The model is useful, inter alia, in understanding the molecular mechanisms of liver cancer, in understanding the genetic alterations that lead to chemoresistance or poor prognosis, and in identifying and evaluating new therapies against hepatocellular carcinomas. The liver cancer model of this invention is made by altering hepatocytes to increase oncogene expression, to reduce tumor suppressor gene expression or both and by transplanting the resulting hepatocytes into a recipient non-human animal. | 2009-01-29 |
20090029873 | Alzheimer's Disease-Specific Alterations of the Erk1/Erk2 Phosphorylation Ratio-Alzheimer's Disease-Specific Molecular Biomarkers (Adsmb) - The present invention relates to methods of diagnosing Alzheimer's Disease as well as to methods of confirming the presence or absence of Alzheimer's Disease in a subject. The present invention is also directed to methods of identifying a lead compound useful for the treatment of Alzheimer's Disease by contacting non-Alzheimer's cells with an amyloid beta peptide, stimulating the cells with a protein kinase C activator, contacting the cells with a test compound, and determining the value of an Alzheimer's Disease-specific molecular biomarker. The present invention is also directed to methods of diagnosing Alzheimer's Disease in a subject by detecting alterations in the ratio of specific phosphorylated MAP kinase proteins in cells after stimulation with a protein kinase C activator. The Alzheimer's Disease-specific molecular biomarkers disclosed herein are useful for the diagnosis of Alzheimer's Disease, monitoring the progression of Alzheimer's Disease in a subject and in screening methods for the identification of compounds for treating or preventing Alzheimer's Disease. The invention is also directed to kits containing reagents for the detection and diagnosis of the presence or absence of Alzheimer's Disease using the Alzheimer's Disease-specific molecular biomarkers disclosed herein. | 2009-01-29 |
20090029874 | FLUORESCENCE BASED BIOSENSOR - A novel biosensor comprises at least one fluorophore and at least two quenchers, and is capable of selectively and specifically detecting the presence of an ion in the presence of other ions. | 2009-01-29 |
20090029875 | Novel Silane Compounds and Use of Same for Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports - The invention relates to novel silane compounds corresponding to the formula (I) below: | 2009-01-29 |
20090029876 | CAPILLARY PINS FOR HIGH-EFFICIENCY MICROARRAY PRINTING DEVICE - This invention provides improved components (e.g. array “pins”, print head, substrate platen, print head platen, and the like) for microarray printing devices as well as microarray printing devices incorporating such components. In one embodiment, this invention provides a microarray print head comprising a plurality of glass or quartz spotting capillaries disposed in a support that maintains a fixed spacing between the spotting capillaries and that permits the spotting capillaries to move in a direction parallel to the long axis of the capillaries. | 2009-01-29 |
20090029877 | Automated System for Isolating, Amplifying, and Detecting a Target Nucleic Acid Sequence Present in a Fluid Sample - An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step. | 2009-01-29 |
20090029878 | DRILLING FLUID, DRILL-IN FLUID, COMPLETITION FLUID, AND WORKOVER FLUID ADDITIVE COMPOSITIONS CONTAINING THERMOSET NANOCOMPOSITE PARTICLES; AND APPLICATIONS FOR FLUID LOSS CONTROL AND WELLBORE STRENGTHENING - In one aspect, this invention relates to the use of thermoset nanocomposite particles as components of drilling fluid, drill-in fluid, completion fluid, and workover fluid additive packages to reduce fluid losses to a formation and/or to enhance a wellbore strength. In another aspect, this invention relates to the use particles of specific gravity ranging from about 0.75 to about 1.75 as components of drilling fluid, drill-in fluid, completion fluid, and workover fluid additive packages to reduce fluid losses to a formation and/or to enhance a wellbore strength. Using embodiments of the invention, reduction of fluid loss and/or enhancement of wellbore strength may be achieved while working with water-based, oil-based, invert emulsion, or synthetic drilling muds. The currently most preferred embodiments of the invention use substantially spherical thermoset nanocomposite particles, possessing a specific gravity from approximately 1.02 to approximately 1.15 wherein the matrix is a terpolymer of styrene, ethylvinylbenzene and divinylbenzene, and wherein carbon black particles possessing a length that is less than about 0.5 microns in at least one principal axis direction are incorporated as a nanofiller. | 2009-01-29 |
20090029879 | PROCESS FOR ENHANCED OIL RECOVERY USING A MICROBIAL CONSORTIUM - A process and related apparatus for enhancing the oil recovery from an oil well are described. An embodiment of the process generally includes selection of a candidate reservoir; collecting oil formation water samples under anaerobic conditions; selecting media and enriching the microbes derived from the formation water; characterizing and identifying the selected consortium; mass scale production of the selected consortium; anaerobically preparing a defined composition nutrient medium, transportation of the nutrient medium by ISO tankers and the consortium by a specially designed field laboratory unit to the selected well treatment site; injecting the medium and consortium into the reservoir of the well; closing the well for the proliferation of microbes for one to three weeks; and allowing the microbes to dislodge oil in the reservoir and thereby enhance recovery of oil from the well. | 2009-01-29 |
20090029880 | Composition containing lonic liquid clay stabilizers and/or shale inhibitors and method of using the same - An ionic liquid may be used to inhibit the swelling and/or disintegration of clay in a subterranean formation. A subterranean clay-containing formation may be treated with the ionic liquid by contacting the formation with a well treatment composition containing the ionic liquid dispersed or dissolved in a carrier fluid. Damage to the formation caused by contact with the well treating composition is reduced or substantially eliminated. | 2009-01-29 |
20090029881 | Heat resistant lithium grease composition and a small motor reduced noise bearing - A heat-resistant noise-reduction grease and a bearing containing the grease for a small motor such as a motor for imaging equipment such as a blower fan and motor bearing for a household electrical appliance such as an air conditioner, which is eco-friendly and excellent in noise-reduction properties is provided. | 2009-01-29 |
20090029882 | PROCESS TO MAKE AN ASHLESS LUBRICATING OIL WITH HIGH OXIDATION STABILITY - A process for making an ashless hydraulic fluid or paper machine oil comprising a) hydroisomerization dewaxing, b) fractionating, c) selecting a fraction having a very high VI, and a high level of molecules with cycloparaffinic functionality, and d) blending the fraction with an ashless antioxidant. A process for making ashless paper machine oil, comprising:
| 2009-01-29 |
20090029883 | METHOD FOR IMPROVING THE OXIDATION STABILITY OF ASHLESS OIL - A method for improving the oxidation stability of an ashless hydraulic fluid or an ashless paper machine oil, comprising: | 2009-01-29 |
20090029884 | HIGH PERFORMANCE LUBRICANTS AND LUBRICANT ADDITIVES FOR CRANKCASE OILS, GREASES, GEAR OILS AND TRANSMISSION OILS - A lubricant additive produced by various processes, including mixing an organophosphate and an organofluorine compound, reacting an organophosphate and an organofluorine compound, reacting a fluorinated organophosphate and an organofluorine compound (with or without molybendum disulfide), or reacting an organophosphate, a metal halide and an organofluorine compound (with or without molybendum disulfide), to produce a reaction mixture comprising the lubricant additive. Also, a lubricant produced by various processes, including mixing an organophosphate and an organofluorine compound, reacting an organophosphate and an organofluorine compound, reacting a fluorinated organophosphate and an organofluorine compound (with or without molybendum disulfide), or reacting an organophosphate, a metal halide and an organofluorine compound (with or without molybendum disulfide), and adding at least a portion of the reaction mixture to a lubricant base. | 2009-01-29 |
20090029885 | META- AND PARA-ARAMID PULP AND PROCESSES OF MAKING SAME - The present invention relates to meta- and para-aramid pulp for use as reinforcement material in products such as seals and friction materials. The pulp comprises (a) fibril free meta-aramid particles, (b) irregularly shaped, para-aramid fibrous structures, and (c) water, whereby the para-aramid fibrous structures contact and are wrapped partially around at least some of the meta-aramid particles. The invention further relates to processes for making such aramid pulp. | 2009-01-29 |
20090029886 | LUBRICANT COMPOSITION FOR RESIN CONVEYOR AND METHOD FOR USING SAME - A lubricant composition for a resin conveyor, comprising specific (A) a nonionic surfactant and (B) water and, if necessary, (C) (a) a cationic surfactant and/or (b) an amphoteric surfactant, and a method for using same. Using a specific nonionic surfactant as the main component provides excellent washing ability, lubricating ability, and stability in storage. In particular, because excellent ability to prevent stress cracking is attained, the lubricant composition for a resin conveyor can be advantageously employed for transporting PET containers. Furthermore, adding a specific cationic surfactant makes it possible to obtain a lubricant composition for a resin conveyor also demonstrating an effect of inhibiting microorganism (fungi) generation, without degrading the various original performances (effects). Furthermore, a preferred method for using those lubricant compositions for resin conveyors is also provided. | 2009-01-29 |
20090029887 | USE OF IONIC LIQUIDS FOR THE NONCUTTING FORMING OF METALLIC WORKPIECES - The invention relates to the use of at least one ionic liquid or a mixture of ionic liquids for noncutting forming processes for metallic workpieces. | 2009-01-29 |
20090029888 | AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS - This invention relates to lubricating oil additives, and to lubricating oil compositions, their method of preparation, and use. More specifically, this invention relates to several novel lubricating oil additives and compositions which contain a tungsten compound and an antioxidant, namely aminic antioxidants such as a secondary diarylamine or an alkylated phenothiazine. The use of the tungsten compound with the secondary diarylamine and/or the alkylated phenothiazine provides improved oxidation and deposit control to lubricating oil compositions. The lubricating oil compositions of this invention are particularly useful as crankcase and transmission lubricants, gear oils and other high performance lubricant applications. | 2009-01-29 |
20090029889 | Hydrocarbon fluids with improved pour point - The addition of alkyl salicylic acids and esters represented by Formula I | 2009-01-29 |
20090029890 | AZEOTROPIC-LIKE COMPOSITIONS WITH 1-METHOXY-2-PROPANOL - Azeotrope-like compositions comprising 1-methoxy-2-propanol and a hydrofluoroether, and uses thereof, are described. | 2009-01-29 |
20090029891 | Soap device and method of combining pieces of soap - A soap device is provided. Such soap device includes a soap bar member manufactured from a first predetermined material and having a first predetermined size and a first predetermined shape. A depressed area is operably disposed in such soap bar member at a predetermined location thereon for receiving and housing at least one predetermined piece of soap. The depressed area has a second predetermined size and a second predetermined shape. | 2009-01-29 |
20090029892 | CLEANING SOLUTION FOR CLEANING SURFACE OF NOZZLE PLATE OF INKJET PRINTHEAD AND METHOD OF CLEANING SURFACE OF NOZZLE PLATE BY USING THE CLEANING SOLUTION - Provided are a cleaning solution for cleaning a surface of a nozzle plate of an inkjet printhead that prints an image by ejecting ink droplets through nozzles and a method of cleaning a surface of a nozzle plate by using the cleaning solution. The cleaning solution includes a solvent; and an additive comprising at least one of a leveling agent and a surfactant, which is added to the solvent. | 2009-01-29 |
20090029893 | Cleaning Liquid For Lithography and Cleaning Method Using Same - Disclosed is a cleaning liquid for lithography which is characterized by containing a mixed organic solvent which is obtained by mixing (A) at least one solvent selected from ketone organic solvents and glycol ether organic solvents, (B) at least one solvent selected from lactone organic solvents and (C) at least one solvent selected from alkoxy benzenes and aromatic alcohols. This cleaning liquid is highly safe and does not have adverse effects on the environment or the human body, while having basic characteristics necessary for a cleaning liquid for lithography. In addition, this cleaning liquid can be stably supplied at low cost. | 2009-01-29 |
20090029894 | METHOD FOR WASHING DEVICE SUBSTRATE - The present invention provides a washing method for a device substrate, capable of sufficiently removing a resist attached to a device substrate, particularly a resist attached to fine pore portions of a pattern having a large aspect ratio. | 2009-01-29 |
20090029895 | HARD SURFACE CLEANING COMPOSITION - The present invention relates to a hard surface cleaning composition comprising a copolymer, wherein said copolymer comprises a zwitterionic unit A or a mixture thereof and another unit B or a mixture thereof, wherein said unit A comprises a betaine group or a mixture thereof and wherein said betaine group of said unit A is a sulphobetaine group or a mixture thereof, and wherein said unit B is derived from vinyl-pyrrolidone. | 2009-01-29 |
20090029896 | Fast Release Granules - The present invention provides a granule that releases antioxidants rapidly. | 2009-01-29 |
20090029897 | Detergent or Cleaning Agent - The invention relates to methods for producing a detergent or cleaning agent dosing unit, comprising the following steps: a) providing a detergent or cleaning agent shaped body in the form of an annular tablet having a cavity with at least two opening faces; b) sealing one opening face of the cavity with a prefabricated, filled and closed water-soluble container by linking the prefabricated sachet with the detergent or cleaning agent shaped body; c) filling the cavity with a composition that has a detergent or cleaning action. The inventive methods allow to jointly produce solid and liquid or flowable detergent or cleaning agent compositions in separate areas of a compact dosing unit. | 2009-01-29 |
20090029898 | Washing or Cleaning Composition Comprising Dye Transfer Inhibitor - Washing or cleaning compositions that contain a surfactant and a fatty alkyl dialkylhydroxyethylammonium salt as a dye transfer inhibitor, as well as processes for making the compositions and for washing or cleaning colored textile fabrics. | 2009-01-29 |
20090029899 | Fabric softening composition - A fabric softening composition having a pH of from 2 to 3 and comprising
| 2009-01-29 |
20090029900 | Personal care article for sequentially dispensing compositions with distinct fragrance characters - The present invention relates to a personal care article that comprises a single chamber package and a liquid personal care product. The package comprises a dispensing orifice, a first zone proximate to the dispensing orifice and a second zone distal to the dispensing orifice. The liquid personal care product comprises a first personal care composition substantially disposed within the first zone and the second personal care composition substantially disposed within the second zone. The first composition comprises a first fragrance character and the second composition comprises a second fragrance character; wherein the first fragrance character is distinct from the second fragrance character. | 2009-01-29 |
20090029901 | Process for Crystallizing Lactose Particles for Use in Pharmaceutical Formulations - A process for producing a plurality of lactose particles comprises subjecting a plurality of lactose particles, to conditions such that at least a portion of smaller lactose particles detach from the plurality of the lactose particles and disperse in the liquid medium; subjecting the liquid medium to conditions sufficient to cause crystallization to occur on the smaller lactose particle surfaces to form larger lactose particles; and subjecting the liquid medium to conditions such that at least a portion of the lactose particles smaller relative to the plurality of larger lactose particles are dissolved in the liquid medium, wherein crystallization occurs on the plurality of larger lactose particles. | 2009-01-29 |
20090029902 | PEPTIDES FOR BINDING CALCIUM CARBONATES AND METHODS OF USE - Combinatorially generated peptides are provided that have binding affinity for calcium carbonates. The peptides may be used to deliver benefit agents to various calcium carbonate surfaces. | 2009-01-29 |
20090029903 | 1,1'-(1,2-Ethynediyl)Bis-Benzene Derivatives As Ptp 1-B Inhibitors - The present invention is related to carboxylic acids of Formula (I) and use thereof for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, polycystic ovary syndrome (PCOS). In particular, the present invention is related to the use of carboxylic acids of Formula (I) to modulate, notably to inhibit the activity of PTPs. | 2009-01-29 |
20090029904 | Compositions and methods for treatment of insulin-resistance diseases - Compositions and methods are provided for modulation of Target of Rapamycin (TOR) activity. Reduction of TOR blocks insulin resistance and metabolic syndrome phenotypes caused by expression of a constitutively activated version of the insulin responsive transcription factor, FOXO. These TOR-mediated responses are also linked with protection against age-dependent functional organ senescence, e.g., heart decline, as well as increased longevity without changes in resistance to starvation and oxidative stresses. | 2009-01-29 |
20090029905 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES - Compounds of formula (I) | 2009-01-29 |
20090029906 | ERYTHROPOIETIN-DERIVED SHORT PEPTIDE AND ITS MIMICS AS IMMUNO/INFLAMMATORY MODULATORS - The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof. | 2009-01-29 |
20090029907 | Recombinant Method for Production of an Erythropoiesis Stimulating Protein - The present invention relates to the recombinant method used for the production of a highly glycosylated form (in total five N linked glycosylations as opposed to three N linked glyosylations in the natural EPO) of erythropoietin. The added sites for glycosylation will result in greater number of carbohydrate chains, and higher sialic acid content than human EPO, which in turn would impart to the recombinant molecule a longer half-life. The invention further relates to the construction of expression cassettes comprising nucleic acid sequences encoding for the highly glycosylated form of Erythropoietin and stable expression in the host cells. The invention further relates to the optimized method for purification of the erythropoiesis stimulating protein. The recombinant EPO according to the invention, and the salts and functional derivatives thereof, may comprise the active ingredient of pharmaceutical compositions for an increase in the hematocrit for treatment of anemia and for restoration of patient well being and quality of life. | 2009-01-29 |
20090029908 | UTEROGLOBIN IN THE TREATMENT OF IgA MEDIATED AUTOIMMUNE DISORDERS - Uteroglobin has been discovered to prevent IgA mediated diseases, such as IgA nephropathy, by preventing the deposition of IgA-Fibronectin immunocomplexes in tissues such as the renal glomeruli. The invention therefore includes methods of treating such diseases by administering therapeutically effective amounts of uteroglobin (and variants or mimetics) to prevent or improve the IgA mediated condition. Transgenic uteroglobin knockout animals, and animals in which uteroglobin-protein expression is reduced by antisense technology, also provide systems for studying IgA mediated diseases, and screening for appropriate treatments. | 2009-01-29 |
20090029909 | Modulation of synaptogenesis - Soluble proteins, e.g. Hevin, can trigger synapse formation; and other soluble proteins, e.g. SPARC antagonize this activity. Such proteins are synthesized in vitro and in vivo by astrocytes. Methods are provided for protecting or treating an individual suffering from adverse effects of deficits in synaptogenesis, or from undesirably active synaptogenesis. | 2009-01-29 |
20090029910 | COMBINATIONS OF SOMATOSTATIN-ANALOGS WITH DIFFERENT SELECTIVITY FOR HUMAN SOMATOSTATIN RECEPTOR SUBTYPES - The present invention relates to a combination of two or more Somatostatin (SRIF) peptidomimetics (also referred to as Somatostatin- or SRIF-analogs) which have different selectivity for the five human somatostatin receptor subtypes, the use of such combination in the treatment of a disease mediated by activation of somatostatin receptors, and to pharmaceutical compositions comprising such a combination. | 2009-01-29 |
20090029911 | Liquid Human Growth Hormone Formulation Containing Polyethylene Glycol - A stable pharmaceutically acceptable aqueous formulation containing human growth hormone, a buffer, polyethylene glycol, a tonicifier such as a sugar alcohol, and optionally, an antimicrobial agent and optionally, a chelating agent. Also disclosed are associated means and methods for preparing, storing and using such formulations. | 2009-01-29 |
20090029912 | Method of enhancing proliferation and/or survival of mesenchymal precursor cells (mpc) - The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals. | 2009-01-29 |
20090029913 | Novel exendin agonist compounds - Novel exendin agonist compounds are provided. These compounds are useful in treating diabetes and conditions which would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying. | 2009-01-29 |
20090029914 | Albumin Fusion Proteins - The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. | 2009-01-29 |
20090029915 | REGULATION OF MINERAL AND SKELETAL METABOLISM - A method is disclosed whereby levels of calcium, phosphate and parathyroid hormone are measured in a patient. The patient is treated with a formulation comprising a compound having phosphotonin activity and thereafter measurements are made again. Dosing of the formulation is adjusted based on measurements with measuring, administering and adjusting dosing continually repeated as needed. | 2009-01-29 |
20090029916 | Fibroblast Growth Factor-14 - Disclosed is a human Fibroblast growth factor-14 polypeptide and DNA(RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for utilizing such polypeptide for promoting wound healing for example as a result of burns and ulcers, to prevent neuronal damage due to associated with stroke and promote neuronal growth, and to prevent skin aging and hair loss, to stimulate angiogenesis, mesodermal induction in early embryos and limb regeneration. Antagonists against such polypeptides and their use as a therapeutic to prevent abnormal cellular proliferation, hyper-vascular diseases and epithelial lens cell proliferation are also disclosed. Diagnostic methods for detecting mutations in the coding sequence and alterations in the concentration of the polypeptides in a sample derived from a host are also disclosed. | 2009-01-29 |
20090029917 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF FIBROTIC CONDITIONS & IMPAIRED LUNG FUNCTION & TO ENHANCE LYMPHOCYTE PRODUCTION - The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells. | 2009-01-29 |