Class / Patent application number | Description | Number of patent applications / Date published |
422504000 | Liquid moving means | 78 |
20100303687 | FLUIDIC DEVICES WITH DIAPHRAGM VALVES - This invention provides fluidic devices, in particular microfluidic devices, with diaphragm valves having low failure rates. Low failure rates are achieved by inhibiting sticking of the diaphragm to functional surfaces such as valve seats, valve chamber and fluidic channels and conduits. One way to implement this is to provide exposed surfaces facing the diaphragm, particularly valve seats, with a low energy material, such as a noble metal, a perfluorinated polymer, a self-assembled monolayer, hard diamond, diamond-like carbon or a metal oxide. In other embodiments, the valves are provided with ridges and the diaphragm is adhered to the fluidic or actuation layer with an adhesive material. | 12-02-2010 |
20110038768 | HEAT-REDUCTION METHODS AND SYSTEMS RELATED TO MICROFLUIDIC DEVICES - A system and method for preventing or reducing unwanted heat in a microfluidic of the device while generating heat in selected regions of the device. | 02-17-2011 |
20110085950 | CENTRIFUGAL FORCE BASED MICROFLUIDIC SYSTEM AND BIO CARTRIDGE FOR THE MICROFLUIDIC SYSTEM - A microfluidic system based on centrifugal force and a bio cartridge for the microfluidic system are provided. The system includes a spindle motor, a rotatable frame detachably mounted on the motor and having a plurality of cells separated by partition walls, and the bio cartridge detachably accommodated in one of the plurality of cells. The bio cartridge includes a chamber for storing a fluid, a channel for transporting the fluid, and a valve for controlling the flow of the fluid. The valve may include a phase transition material, and exothermic minute particles dispersed in the material and generating heat when energy is applied thereto. | 04-14-2011 |
20110129395 | MICROFLUIDIC ASSEMBLY - Embodiments of a microfluidic assembly comprise at least two adjacent microstructures and a plurality of interconnecting fluid conduits which connect an outlet port of one microstructure to an inlet port of an adjacent microstructure. Each microstructure comprises an inlet flow path and an outlet flow path not aligned along a common axis. Moreover, the microfluidic assembly defines a microfluidic assembly axis along which respective inlet ports of adjacent microstructures are oriented or alternatively along which respective outlet ports of adjacent microstructures are oriented, and each microstructure is oriented relative to the microfluidic assembly axis at a nonorthogonal angle. | 06-02-2011 |
20110194995 | MICROFLUID DEVICE - The present invention relates to a microfluid device for discharging a fluid or a mixture of fluids including a discharge channel, at least one main fluid supply channel which leads into at least one secondary supply channel which is essentially situated in the same plane as the discharge channel, and which leads laterally towards the discharge channel and, in turn, leads into an inlet channel situated above or below the discharge channel, the inlet channel entering into the discharge channel from its top or bottom side via at least one inlet opening. The at least one inlet channel has a cross-sectional shape which changes in the longitudinal direction and/or in that the at least one inlet opening has an opening width changing in the transverse direction of the discharge channel. | 08-11-2011 |
20110206576 | MICROFLUIDIC MIXING AND REACTION SYSTEMS FOR HIGH EFFICIENCY SCREENING - Microfluidic devices are described that include a rigid base layer, and an elastomeric layer on the base layer. The elastomeric layer may include at least part of a fluid channel for transporting a liquid reagent, and a vent channel that accepts gas diffusing through the elastomeric layer from the flow channel and vents it out of the elastomeric layer. The devices may also include a mixing chamber fluidly connected to the fluid channel, and a control channel overlapping with a deflectable membrane that defines a portion of the flow channel, where the control channel may be operable to change a rate at which the liquid reagent flows through the fluid channel. The devices may further include a rigid plastic layer on the elastomeric layer. | 08-25-2011 |
20120039769 | DISK-BASED FLUID SAMPLE COLLECTION DEVICE - A fluid sample collection device for a disk-based fluid separation system is disclosed. The disk-based separation system includes a compact microfluidic disk with at least one flow channel pattern formed on a side surface of the disk. At least one orifice is formed on an outflow boundary of the disk and is designed in fluid communication with the flow channel pattern through a communication channel. The fluid sample collection device includes at least one collection tube having an open end serving as a fluid receiving end and corresponding to the orifice of the disk with a distance. When the disk is rotated, at least a portion of fluid sample in a sample processing reservoir formed on the disk is delivered by centripetal force through the communication channel and the orifice, and finally the expelling fluid sample is collected in the collection tube. | 02-16-2012 |
20120039770 | MICROFLUIDIC DEVICE INCLUDING MICROVALVE - A microfluidic device including at least one microvalve which controls a flow of a fluid, where the at least one microvalve includes: a pneumatic layer, a fluidic layer disposed opposite to the pneumatic layer; an elastomer membrane disposed between the pneumatic layer and the fluidic layer; and an asymmetric valve seat protruding from a surface of the fluidic layer toward a surface of the elastomer membrane and asymmetrically dividing a space between the fluidic layer and the elastomer membrane. | 02-16-2012 |
20120058026 | Microfluidic ejection device and method of manufacturing the same - There are disclosed a microfluidic ejection device and a method of manufacturing the same. The microfluidic ejection device includes a flow path plate having an inlet into which a microfluid is drawn, a pressure chamber connected with the inlet and having formed therein, a plurality of chamber units divided by a plurality of partitions, and a nozzle connected with the pressure chamber and ejecting the microfluid by integrating the microfluid, having passed through the plurality of chamber units, into a single flow path; and actuators formed on an upper portion of the flow path plate so as to respectively correspond to the plurality of chamber units and providing driving force for ejecting the microfluid from the pressure chamber to the nozzle. The microfluidic ejection device has superior microfluidic ejection performance because variations in pressure within the pressure chamber can be accurately adjusted. | 03-08-2012 |
20120128549 | MICROFLUIDIC SYSTEMS AND CONTROL METHODS - The systems and methods disclosed herein include a microfluidic system, comprising a pneumatic manifold having a plurality of apertures, and a chip manifold having channels disposed therein for routing pneumatic signals from respective ones of the apertures to a plurality of valves in a microfluidic chip, wherein the channels route the pneumatic signals in accordance with a configuration of the plurality of valves in the microfluidic chip. | 05-24-2012 |
20120156113 | FLUIDIC SYSTEMS, FLUID CONTAINERS AND PROCESSES FOR WASHING FLUID LINES - A process for automatically washing fluid lines of a fluidic system for combining liquid samples with one or more reagents, the system being provided with at least one main line connected to one or more reagent lines for feeding reagents, each of which being connectable to a reagent container by a fluidic connector, at least one sample intake for intaking samples and at least one pressure actuator for generating a positive or negative pressure in the fluid lines. The process comprises one or more procedures selected from: procedure I: drawing wash fluid from a wash fluid reservoir connected to the main line into the main line and discharging wash fluid into a waste compartment for receiving waste fluid of a cleaning container connected to at least one reagent line by the fluidic connector; procedure II: drawing wash fluid from at least one fluid compartment containing wash fluid of at least one cleaning container connected to at least one reagent line by the fluidic connector into the main line and discharging wash fluid from the main line into at least one waste compartment for receiving waste fluid of the cleaning container; procedure III: drawing wash fluid from at least one fluid compartment containing wash fluid of a cleaning container connected to at least one first reagent line into the main line and discharging wash fluid from the main line into at least one waste compartment for receiving waste fluid of a cleaning container connected to at least one second reagent line being different from the at least one first reagent line. | 06-21-2012 |
20120171085 | DEVICE AND METHOD FOR TRANSPORTING MAGNETIC OR MAGNETISABLE BEADS - The present invention relates to a device ( | 07-05-2012 |
20120201724 | MICRO MIXER AND MICROFLUIDIC CHIP - There are provided a micro mixer capable of efficiently mixing at least two types of liquids in a simple structure and a microfluidic chip provided with the micro mixer. In order to achieve the object, the micro mixer includes a minute passage through which first and second liquids are caused to flow respectively, and a mixing vessel in which a liquid injecting port caused to communicate with the minute passage is provided in a bottom part, and the liquid injecting port is provided in a shifted position from a center of the bottom part in the bottom part. Moreover, the liquid injecting port may be provided in a shifted position from a center line of the mixing vessel. | 08-09-2012 |
20120230888 | TEMPERATURE CONTROL SYSTEM - For heating or cooling a sample contained in a vessel portion through a heat transfer member held in contact with the vessel portion, there is used the vessel portion, which has a part formed of an elastic member, expands and contracts for injection and discharge of the sample, is closed other than a connecting port with a channel connected to the vessel, and expands and contracts for injection and discharge of the sample. The vessel portion expands correspondingly to the injection when the sample is injected through an inflow path serving as the channel into the vessel portion contracting in a non-contacting state with the heat transfer member. A predetermined amount of sample is injected into the vessel portion so as to expand the vessel portion, and the vessel portion comes into contact with the heat transfer member. The vessel portion is heated or cooled through the heat transfer member. | 09-13-2012 |
20120244043 | ELASTOMERIC GASKET FOR FLUID INTERFACE TO A MICROFLUIDIC CHIP - The present invention relates to microfluidic devices that include a reliable seal between a substrate of the device and a fluid transport mechanism. The devices of the invention include at least one internal channel, and at least one port in fluid communication with the channel. A seal is associated with the port and is configured to receive a fluid transport mechanism. The seal is formed from an elastomeric material that is compatible for use with fluorinated oil and resists flaking and degradation. | 09-27-2012 |
20130149216 | DEVICE FOR STORING REAGENT AND METHOD OF DISCHARGING REAGENT THEREOF - Provided are a device for storing a reagent capable of being adhered to a biochip and supplying the stored reagent to the biochip, and a method of discharging a reagent thereof. The device for storing a reagent includes an elastic film pressurizing part configured to pressurize an elastic film by magnetic force, and a reagent discharging part configured to store the reagent and discharge the reagent through an outlet by using the deformation in the elastic film due to the pressurization. According to the present invention, a magnetic force controlling device can be small-sized and the reagent can be automatically, high-precisely, and reproducibly supplied through the magnetic force control. | 06-13-2013 |
20130156658 | MICROFLUIDIC DEVICE AND METHOD OF MANUFACTURING THE SAME - Embodiments of the disclosure describe a microfluidic device and a method of manufacturing the same. An embodiment of the microfluidic device includes a first substrate in which a micro-flow path and a valve seat protruding toward the micro-flow path are formed; a second substrate disposed to face the first substrate and in which a cavity corresponding to the valve seat is formed; and a polymer film disposed between the first substrate and the second substrate and comprising a bonding unit bonded to the first and second substrates and a variable unit having a variable shape according to pneumatic pressure of the cavity, wherein the variable unit has a curvature and is spaced apart from the valve seat when pneumatic pressure is not provided to the variable unit. | 06-20-2013 |
20130183211 | APPARATUS AND METHODS FOR TRANSFERRING MATERIALS BETWEEN LOCATIONS POSSESSING DIFFERENT CROSS-SECTIONAL AREAS WITH MINIMAL BAND SPREADING AND DISPERSION DUE TO UNEQUAL PATH-LENGTHS - Non-limiting exemplary embodiment(s) of apparatus(es) and method(s) are described for the conveyance of fluid media and entrained materials between two or more locations, each possessing a different cross-sectional area. Equidistant pathways incorporated into uniquely designed conduits enable this transference to occur with minimal band spreading and separation resolution loss due to undesirable flow patterns that arise from end effects. The design enables the conduits to be employed with locations of almost any description including process channels, surfaces, or even open volume of any size and used for almost any purpose. The conduits and/or associated locations may be empty of any contents or filled with gelatinous, porous, granular, or particulated material. The design of non-limiting exemplary embodiment(s) of apparatus(es) and method(s) may be easily adapted or configured as necessary. | 07-18-2013 |
20130243664 | MICROFLUIDIC ELEMENT FOR ANALYSIS OF A SAMPLE LIQUID - A microfluidic element for analysis of a fluid sample having a substrate and a microfluidic transport system having a channel structure enclosed by the substrate and a covering layer. The channel structure comprises a channel with two side walls as well as a chamber that is in fluid communication with the channel. The chamber has a chamber wall with an inlet orifice. The channel comprises a channel section and a valve section adjoining the channel section, wherein the valve section is in fluid communication with the inlet orifice in the chamber wall in such a way that a fluid can flow from the channel through the valve section and into the chamber. The valve section has a fluid transport cross-section, which enlarges in flow direction. The fluid transport cross-section in the valve section is greater than the fluid transport cross-section in the preceding channel section. | 09-19-2013 |
20130251604 | MICROFLUIDIC DEVICE AND METHOD OF MANUFACTURING THE SAME - A microfluidic device comprising a first substrate including a micro-flow path and a valve seat protruding into the micro-flow path, a second substrate coupled to the first substrate and including a cavity aligned with the valve seat, and a valve gate film provided between the first substrate and the second substrate, such that the valve gate film opens and closes the micro-flow path with air pressure applied to the cavity, wherein a surface of the valve seat is separated from the valve gate film at the initial stage such that the micro-flow path is opened at the initial stage, and the valve gate film moves to be in contact with the surface of the valve seat so that the micro-flow path is closed when air pressure is applied to the cavity. | 09-26-2013 |
20130287647 | Microfluidic Interface - The invention allows for the formation of robust, reproducible, non-permanent connections to microchips. The connections are formed using either indexing arms or multiple fitting holder heads which are capable of forming a compression seal to a port located at any position on the surface of the microchip. The sealing force is user-defined and can be tightly controlled with integrated force sensors. In addition, the sealing force is monitored with a force sensor and force compensation mechanism ensuring that the desired force is maintained. The device is compatible with all microchip architectures. Alterations to the microchip surface is avoided as connections are established using instrumentation rather than processing steps. Further, the process is automatable allowing for exchanging microchips and subsequently creating electrical and fluidic connections in an automated fashion. Optionally, the integration of leak sensors to monitor leaks are included. | 10-31-2013 |
20130330247 | Fluidics Apparatus for Surface Acoustic Wave Manipulation of Fluid Samples, Use of Fluidics Apparatus and Process for the Manufacture of Fluidics Apparatus - A fluidics apparatus for manipulation of at least one fluid sample is disclosed. A manipulation surface locates the fluid sample. A surface acoustic wave (SAW) generation material layer is provided. This is a polycrystalline material, textured polycrystalline material, biaxially textured polycrystalline material, microcrystalline material, nanocrystalline material, amorphous material or composite material. A transducer electrode structure arranged at the SAW generation material layer provides SAWs at the manipulation surface for interaction with the fluid sample. The manipulation surface has a phononic structure, for affecting the transmission, distribution and/or behaviour of SAWs at the manipulation surface. The apparatus is typically manufactured by reel-to-reel processes, to reduce the unit cost to a level at which the apparatus can be considered to be disposable after a single use. | 12-12-2013 |
20130343966 | Microfluidic Device for the Manipulation of Particles - A microfluidic device for isolating particles of at least one given type of a sample; the device is designed to be connected to an apparatus through a plurality of electrical connectors and comprises a system of microfluidic channels and a flash memory, which contains information on the structure (arrangement and geometry of the various components) of the system of microfluidic channels, a map of non-functioning parts of the device, the maximum number of uses and the maximum time of use of the device; the memory has portions allocated for storing the number of times and the time of use of the device. | 12-26-2013 |
20140010735 | FLUID-CONTROLLING DEVICE FOR MICROCHIP AND USE THEREOF - The present invention relates to a fluid-controlling device ( | 01-09-2014 |
20140241955 | SAMPLE LIQUID INJECTION JIG SET - A liquid injecting jig is provided. The liquid injecting jig includes a jig configuration including a plurality of parts adapted to be in cooperative engagement so as to position a channel within the jig configuration, wherein the jig configuration is adapted to fit an opening through which the channel is adapted to be received so as to expose the channel from the jig configuration. A jig set, a microchip case, and a microchip set are also provided. | 08-28-2014 |
20140294697 | SEQUENTIAL LATERAL FLOW CAPILLARY DEVICE FOR ANALYTE DETERMINATION - Disclosed is a lateral flow capillary device and uses thereof comprising a unipath capillary flow matrix and a plurality of reservoirs each in fluid communication with the capillary flow matrix. The device includes one or more pressure delivery systems configured to urge capillary flow matrix toward a portion of the housing in which it resides, such that a substantially uniform pressure is applied over a portion of the capillary flow matrix. | 10-02-2014 |
20140377144 | In Situ Mixing in Microchannels - The present invention provides methods, systems and apparatus in which one fluid passes through an orifice or orifices and mixes with another fluid as it flows through a microchannel. | 12-25-2014 |
20150056110 | System for Treating Liquids - A system for treating liquids, comprising: especially for analysis and/or synthesis of liquids, a fluidics unit having at least one functional unit; at least one liquid storage unit of the first type; at least one liquid storage unit of second type; a first liquid line; and a second liquid line, wherein a flow of liquid through the first liquid line directed from the fluidics unit to the liquid storage unit of first type is blocked, at least at times, by means of a first valve, and a flow of liquid through the second liquid line in the direction from the liquid storage unit of second type to the fluidics unit is blocked, at least at times, by means of a second valve. | 02-26-2015 |
20150110689 | METHOD FOR MANUFACTURING MODULAR MICROFLUIDIC PAPER CHIPS USING INKJET PRINTING - The present invention relates to a method for manufacturing a module type microfluidic chip comprising: (a) printing electrode patterns on a substrate using a conductive ink and inkjet printing; (b) cutting the printed electrode patterns; and (c) assembling the cut electrode patterns to manufacture the module type microfluidic paper chip. Unlike the traditional method for manufacturing printed circuit substrate using a patterning agent or device, the method of the present invention only incorporates a simple printing process using an inkjet printer, and thus patterning can be simplified and various types of chips can be manufactured depending on the assembly type of electrode patterns. Accordingly, inexpensive, economical, and highly utilizable microfluidic chips can be provided using the method of the present invention. | 04-23-2015 |
20160096174 | Capacitance Detection in a Droplet Actuator - A method, circuit and apparatus for detecting capacitance on a droplet actuator, inter alia, for determining the presence, partial presence or absence of a droplet at an electrode on a droplet actuator by: (a) providing a droplet actuator comprising: (i) a substrate comprising electrodes arranged on the substrate for conducting droplet operations on a surface of the substrate; (ii) a capacitance detection circuit for detecting capacitance at the droplet operations surface at one or more of the electrodes; (b) detecting capacitance at the droplet operations surface at one or more of the electrodes; and (c) determining from the capacitance the presence, partial presence or absence of a droplet at the droplet operations surface at the electrode. | 04-07-2016 |
20160129444 | COALESCENCE OF DROPLETS - The present invention generally relates to microfiuidics, and, in particular, to systems and methods for coalescing or fusing droplets. In certain aspects, two or more droplets within a microfluidic channel are brought together and caused to coalesce without using electric fields or charges. For example, in certain embodiments, droplets stabilized with a surfactant may be disrupted, e.g., by exposing the droplets to a solvent able to alter the surfactant, which may partially destabilize the droplets and allow them to coalesce. In some instances, the droplets may also be physically disrupted to facilitate coalesce. In addition, in some cases, the positions of one or more droplets may be controlled within a channel using a groove in a wall of the channel. For example, a droplet may at least partially enter the groove such that the position of the droplet is at least partially controlled by the groove. | 05-12-2016 |
20160158748 | SINGLE-SIDED LIGHT-ACTUATED MICROFLUIDIC DEVICE WITH INTEGRATED MESH GROUND - Single-sided optoelectrowetting (SSOEW)-configured substrates are provided, as well as microfluidic devices that include such substrates. The substrates can include a planar electrode, a photoconductive (or photosensitive) layer, a dielectric layer (single-layer or composite), a mesh electrode, and a hydrophobic coating. Fluid droplets can be moved across the hydrophobic coating of such substrates in a light-actuated manner, upon the application of a suitable AC voltage potential across the substrate and the focusing of light into the photoconductive layer of the substrate in a location proximal to the droplets. Walls can be disposed upon the substrates to form the microfluidic devices. Together the walls and substrate can form a microfluidic circuit, through which droplets can be moved. | 06-09-2016 |
20160158757 | ACTUATED MICROFLUIDIC STRUCTURES FOR DIRECTED FLOW IN A MICROFLUIDIC DEVICE AND METHODS OF USE THEREOF - A microfluidic device can comprise a plurality of interconnected microfluidic elements. A plurality of actuators can be positioned abutting, immediately adjacent to, and/or attached to deformable surfaces of the microfluidic elements. The actuators can be selectively actuated and de-actuated to create directed flows of a fluidic medium in the microfluidic (or nanofluidic) device. Further, the actuators can be selectively actuated and de-actuated to create localized flows of a fluidic medium in the microfluidic device to move reagents and/or micro-objects in the microfluidic device. | 06-09-2016 |
20160184821 | LATERAL/VERTICAL TRANSISTOR STRUCTURES AND PROCESS OF MAKING AND USING SAME - A microfluidic device can include a base an outer surface of which forms one or more enclosures for containing a fluidic medium. The base can include an array of individually controllable transistor structures each of which can comprise both a lateral transistor and a vertical transistor. The transistor structures can be light activated, and the lateral and vertical transistors can thus be photo transistors. Each transistor structure can be activated to create a temporary electrical connection from a region of the outer surface of the base (and thus fluidic medium in the enclosure) to a common electrical conductor. The temporary electrical connection can induce a localized electrokinetic force generally at the region, which can be sufficiently strong to move a nearby micro-object in the enclosure. | 06-30-2016 |
20180021778 | VENTED MICROFLUIDIC RESERVOIRS | 01-25-2018 |
20190143325 | PLURALITY OF FILTERS | 05-16-2019 |
422505000 | Pump | 16 |
20110293489 | MICROFLUIDIC CHIPS AND ASSAY SYSTEMS - The systems and methods described herein include a microfluidic chip having a plurality of microfeatures interconnected to provide a configurable fluid transport system for processing at least one reagent. Inserts are provided to removably interfit into one or more of the microfeatures of the chip, wherein the inserts include sites for interactions with the reagent. As will be seen from the following description, the microfluidic chip and the inserts provide an efficient and accurate approach for conducting parallel assays. | 12-01-2011 |
20120183455 | LABORATORY SYRINGE PUMPS - A syringe pump which includes a pusher block is slidably mounted on bearings on one or more guide rails. The pusher block is advanced or retracted by a lead screw having an axis which is offset from the axis of the one or more guide rails which are supported at their respective ends by support blocks, wherein forward and/or trailing sides of the pusher block bearings are extended, and wherein the guide rail support blocks include recesses for accommodating the extended ends of the pusher block slide bearings. In another embodiment, the syringe pump includes quick connect-disconnect fixtures for loading and unloading syringes. Other mechanical, and programmable improvements are described in the specification. | 07-19-2012 |
20120201725 | MICRO-FLUIDIC DEVICE - Embodiments described herein provide micro-fluidic systems and devices for use in performing various diagnostic and analytical tests. According to one embodiment, the micro-fluidic device includes a sample chamber for receiving a sample, and a reaction chamber for performing a chemical reaction. A bubble jet pump is structured on the device to control delivery of a fluid from the sample chamber to the reaction chamber. The pump is fluidically coupled to one or more chambers of the device using a fluidic channel such as a capillary. A valve may be coupled to one or more chambers to control flow into and out of those chambers. Also, a sensor may be positioned in one or more of the chambers, such as the reactant chamber, for sensing a property of the fluid within the chamber as well as the presence of a chemical within the chamber. | 08-09-2012 |
20130136671 | REAGENT FLUID DISPENSING DEVICE, AND METHOD OF DISPENSING A REAGENT FLUID - According to various embodiments, a reagent fluid dispensing device may be provided. The reagent fluid dispensing device may include a chamber for receiving a reagent fluid, the chamber having a first opening and a second opening; a first fluid conduit connected to the first opening of the chamber; a reservoir connected to the first fluid conduit, the reservoir having a first opening, wherein the first opening of the reservoir is connected to the first fluid conduit to form a passive valve, wherein the reservoir is dimensionalized for storing a predetermined volume of the reagent fluid; and a pneumatic conduit connected to the second opening of the chamber, wherein selective application of pneumatic pressure to the chamber through the pneumatic conduit transfers the reagent fluid from the reservoir to the chamber through the first fluid conduit. According to various embodiments, a microfluidic device including the reagent fluid dispensing device, and a method of dispensing a reagent fluid may be provided. | 05-30-2013 |
20130209327 | MICROFLUIDIC CHIPS AND ASSAY SYSTEMS - The systems and methods described herein include a microfluidic chip having a plurality of microfeatures interconnected to provide a configurable fluid transport system for processing at least one reagent. Inserts are provided to removably interfit into one or more of the microfeatures of the chip, wherein the inserts include sites for interactions with the reagent. As will be seen from the following description, the microfluidic chip and the inserts provide an efficient and accurate approach for conducting parallel assays. | 08-15-2013 |
20130209328 | MICROFLUIDIC CHIP COMPRISING SEVERAL CYLINDER-PISTON ARRANGEMENTS - A microfluidic arrangement including a substrate in which a mircofluidic structure having several adjacent channels and at least one common supply line, into which the adjacent channels merge, is formed. Each of the adjacent channels form the cylinder of a cylinder-piston arrangement for receiving an associated piston. A method for producing the type of microfluidic-arrangement is also disclosed. | 08-15-2013 |
20140010736 | MICROFLUIDIC DEVICES FOR FLUID MANIPULATION AND ANALYSIS - The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis. | 01-09-2014 |
20140134075 | PHOTORESPONSIVE GAS-GENERATING MATERIAL, MICROPUMP AND MICROFLUID DEVICE - The present invention provides a photoresponsive gas-generating material that is to be used in a micropump of a microfluid device having fine channels formed therein, and is capable of effectively generating gases for transporting a microfluid in response to light irradiation and transporting the microfluid at an improved transport efficiency. The present invention also provides a micropump incorporating the photoresponsive gas-generating material. | 05-15-2014 |
20140161687 | GAS-GENERATING MATERIAL AND MICRO PUMP - Provided is a gas-generating material which can generate a gas in a large amount per unit time and has high storage stability. | 06-12-2014 |
20140322100 | Method and Device for Producing a Microfluidic Analysis Cartridge - A method for producing a pneumatically actuatable microfluidic analysis cartridge includes closing a joining side of a fluidic part of the analysis cartridge with a first fluid-tight elastic membrane and/or closing a joining side of a pneumatic part of the analysis cartridge with a second membrane. The fluidic part is configured to perform fluidic basic operations of a biochemical analysis process, and the pneumatic part is configured to control the basic operations using air pressure. The joining side of the fluidic part and the joining side of the pneumatic part are aligned, and the fluidic part and the pneumatic part are connected to form the analysis cartridge. | 10-30-2014 |
20140377145 | MICROFLUIDIC MIXING DEVICE - A microfluidic mixing device comprises a main channel and a number of secondary channels extending from a portion of the main channel and entering another portion of the main channel. A number of actuators are located in the secondary channels to pump fluids through the secondary channels. A microfluidic mixing system comprises a microfluidic mixing device. The microfluidic mixing device comprises a main fluid mixing channel, a number of main channel actuators to pump fluid through the main fluid mixing channel, a number of secondary channels fluidly coupled to the main fluid mixing channel, and a number of secondary channel actuators to pump fluids through the secondary channels. The microfluidic mixing device also comprises a fluid source, and a control device to provide fluids from the fluid source to the microfluidic mixing device and activate the main channel actuators and secondary channel actuators. | 12-25-2014 |
20140377146 | Microfluidic Assay Operating System and Methods of Use - A pneumatically driven portable assay cartridge having analyte capture regions associated with microfluidic channels within its interior, the portable cartridge having pneumatic ports clampable against pneumatic ports of an operating instrument for controlled application of positive pressure and vacuum to pneumatic operating channels within the cartridge, the cartridge having a well for receiving sample from a user and microfluidic channels that include pneumatically operated pistons and valves controllable by the pneumatic operating channels to cause all flows of the assay from the reservoirs through reaction regions within the cartridge to on-board waste reservoir during conduct of the assay. | 12-25-2014 |
20150321193 | LOW ELASTICITY FILMS FOR MICROFLUIDIC USE - Microfluidic circuit elements, such as a microvalve, micropump or microvent, formed of a microcavity divided by a diaphragm web into a first subcavity bounded by a first internal wall and a second subcavity bounded by a second internal wall, where the diaphragm web is characterized as a thin film having a first state contacting the first internal wall and a second state contacting the second internal wall and exhibiting essentially no elasticity in moving between the first state and the second state, the thin film web having been stretched beyond its yield point before or during use are provided. The disclosed elements enable faster and more efficient cycling of the diaphragm in the microcavity and increases the diaphragm surface area. In a preferred embodiment, the microfluidic circuit element is pneumatically driven and controls the motion of fluids in a microassay device. | 11-12-2015 |
20150352549 | FLUIDIC CIRCUITS AND RELATED MANUFACTURING METHODS - Fluidic cartridges, and manufacture thereof, having a plurality of circuit element subtypes containing pneumatically operated diaphragm members, where the diaphragm materials are selected for yield point, chemical resistance, breathability and other properties individually according to the fluidic element subtype are provided. A process of in-situ edge-bonded decoupage for forming diaphragm members inside a cartridge, and fluidic circuits having diaphragm members as active and passive circuit elements, including pumps, valves, vents, waste receptacles, reagent reservoirs, and cuvettes with optical windows, where the material composition of each individual diaphragm member may be selected from an assortment of materials during manufacture are also provided. | 12-10-2015 |
20160121329 | MICROFLUIDIC DEVICE - Microfluidic devices and in particular microfluidic devices incorporating a cascading valve arrangement for selectively controlling the flow of a fluid within the microfluidic device are described. Specific examples of a microfluidic device comprising a sacrificial valve ( | 05-05-2016 |
20160158753 | FLUID PROCESSING AND CONTROL - A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers. One or more of the chambers may be a processing chamber which includes two ports configured to selectively engage the at least one external port of the body, and a fluid processing material such as an enrichment material or a depletion material. In some embodiments, one or more chambers may include a separation channel, and an electric field may be applied across the separation channel. | 06-09-2016 |
422506000 | Centrifugal force | 8 |
20110236277 | MICROFLUID CONTROL DEVICE AND METHOD OF MANUFACTURING THE SAME - Provided are a plastic microfluid control device having a multi-step microchannel and a method of manufacturing the same. The device includes a lower substrate, and a fluid channel substrate contacting the lower substrate and having a multi-step microchannel having at least two depths in a side coupling to the lower substrate. Thus, the device can precisely control the fluid flow by controlling capillary force in a depth direction of the channel by controlling the fluid using the multi-step microchannel having various channel depths. A multi-step micropattern is formed by repeating photolithography and transferred, thereby easily forming the multi-step microchannel having an even surface and a precisely controlled height. | 09-29-2011 |
20120207654 | MICROFLUIDIC DEVICE - A microfluidic device having a chamber with a fluid discharge configuration is provided. The microfluidic device includes a platform including a chamber configured to accommodate a fluid therein. The chamber includes an inner sidewall and an outer sidewall disposed outwardly from the inner sidewall in a radial direction of the platform. The outer sidewall includes a first point located closest to a center of the platform, and a second point located farthest from the center of the platform. A distance from the center of the platform to an arbitrary third point on the outer sidewall between the first point and the second point increases from the first point to the second point, so that the fluid near the first point is guided to the second point by centrifugal force during rotation of the platform. | 08-16-2012 |
20120230889 | MICROCHIP - A microchip includes a fluid circuit defined by a space formed in the microchip and migrates a liquid present in the fluid circuit to a desired position in the fluid circuit by applying a centrifugal force, the fluid circuit being made of thermoplastic resin. The thermoplastic resin is a polymer having an alkyl group of more than 3 carbon atoms as side chains. | 09-13-2012 |
20130209329 | MICROCHIP - A microchip which includes a fluid circuit defined by a space formed in the microchip and migrates a liquid present in the fluid circuit to a desired position in the fluid circuit by an applied centrifugal force, and a movement path control region (a surface region where an uneven pattern is formed on an inner surface of the fluid circuit) for controlling a movement path of the fluid. | 08-15-2013 |
20130236376 | Microfluidic Test Carrier for Apportioning a Liquid Quantity Into Subquantities - A microfluidic test carrier having a substrate, covering layer, and capillary structure formed in the substrate is provided. The capillary structure is enclosed by the substrate and covering layer and comprises a receiving chamber, sample chamber and connection channel between the receiving and sample chambers. The receiving chamber has two boundary surfaces and a side wall, wherein one boundary surface forms the bottom and the other forms the cover. The receiving chamber has a surrounding venting channel and dam between the receiving chamber and venting channel. The dam and venting channel form a capillary stop configured as a geometric valve, through which air from the receiving chamber can escape into the venting channel. The connecting channel between the venting channel outflow and sample chamber inflow controls fluid transport from the receiving chamber into the sample chamber. The capillary stop is configured to prevent autonomous fluid transport from the receiving chamber. | 09-12-2013 |
20130287648 | DISK-BASED FLUID SAMPLE COLLECTION DEVICE - A fluid sample collection device for a disk-based fluid separation system is disclosed. The disk-based separation system includes a compact microfluidic disk with at least one flow channel pattern formed on a side surface of the disk. At least one orifice is formed on an outflow boundary of the disk and is designed in fluid communication with the flow channel pattern through a communication channel. The fluid sample collection device includes at least one collection tube having an open end serving as a fluid receiving end and corresponding to the orifice of the disk with a distance. When the disk is rotated, at least a portion of fluid sample in a sample processing reservoir formed on the disk is delivered by centripetal force through the communication channel and the orifice, and finally the expelling fluid sample is collected in the collection tube. | 10-31-2013 |
20140314636 | Microchip - There is provided a microchip including a fluid circuit composed of a space formed inside, and causing a liquid present in the fluid circuit to move within the fluid circuit by application of centrifugal force, the microchip including: an opening provided in a surface of the microchip and connected to the fluid circuit; a lid portion for opening and closing the opening; and a specimen take-in portion provided at the lid portion or in the opening, for taking in a specimen. | 10-23-2014 |
20160038939 | MICROFLUIDIC DEVICE - Provided is a microfluidic device having a structure in which scattering of a sample can be prevented. The microfluidic device includes: a platform including: a sample injection hole, at least one chamber configured to accommodate a sample introduced through the sample injection hole, at least one channel connected to the at least one chamber; and a cover disposed over the sample injection hole, wherein a gap is disposed between the sample injection hole and the cover. | 02-11-2016 |
422507000 | Capillary action | 18 |
20110116993 | Virus/Nanowire Encapsulation within Polymer Microgels for 2D and 3D Devices for Energy and Electronics - Methods and apparatuses for encapsulating inorganic micro- or nanostructures within polymeric microgels are described. In various embodiments, viruses are encapsulated with microgels during microgel formation. The viruses can provide a template for in situ synthesis of the inorganic structures within the microgel. The inorganic structures can be distributed substantially homogeneously throughout the microgel, or can be distributed non-uniformly within the microgel. The inventive microgel compositions can be used for a variety of applications including electronic devices, biotechnological devices, fuel cells, display devices and optical devices. | 05-19-2011 |
20110129396 | VOLUMETRIC SAMPLING PIPETTE - A volumetric micropipette for sampling and dispensing a precise quantity of liquid comprising an elongated hollow tubular body configured to draw liquid by capillary action: a reservoir connected proximate the upper end of the tubular body and a deformable hollow bulb connected to the reservoir and having an opening in a wall thereof to allow liquid to be drawn into the tubular body by capillary action. The reservoir is laterally offset with respect to the tubular body and has at least a portion thereof below the upper end of the tubular body. | 06-02-2011 |
20110311407 | MICROFLUIDIC BOILING-INITIATED VALVE - A microfluidic valve having an inlet for receiving a flow of liquid, an outlet for outputting the flow of liquid, a meniscus anchor between the inlet and the outlet such that the flow from the inlet towards the outlet stops at the meniscus anchor where the liquid forms a meniscus, and, a valve heater for heating the meniscus such that the meniscus unpins from the meniscus anchor such that the flow towards the outlet resumes. | 12-22-2011 |
20130164193 | SEQUENTIAL LATERAL FLOW CAPILLARY DEVICE FOR ANALYTE DETERMINATION - Disclosed is a lateral flow capillary device and uses thereof comprising a unipath capillary flow matrix and a plurality of reservoirs each in fluid communication with the capillary flow matrix. The device includes one or more pressure delivery systems configured to urge capillary flow matrix toward a portion of the housing in which it resides, such that a substantially uniform pressure is applied over a portion of the capillary flow matrix. | 06-27-2013 |
20130183212 | BENT MICROSTRUCTURES FOR SAMPLING, TRANSPORTING OR DISPENSING A FLUID MEDIA - A device for sampling, transporting and/or disposal of fluid media in the nI and μl-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc. | 07-18-2013 |
20130195733 | CAPILLARY DISPENSER - A capillary dispenser includes at least one plunger-cylinder unit having a cylinder module and a plunger module disposed together on an axis. The cylinder module has an inner cylinder that is pneumatically connected to at least one capillary. The plunger module includes a hollow plunger that is closable on one side and is movable in the inner cylinder along the axis between an upper end position and a lower end position of the plunger module. | 08-01-2013 |
20140004019 | CAPILLARY FLUID FLOW CONTROL | 01-02-2014 |
20140030166 | LIQUID DISPENSING DEVICE - A droplet dispensing apparatus has a piston rod driven by a solenoid, the rod for connection to a piston of a droplet dispensing syringe, in which the output member from the solenoid is directly connected to the rod through the entire impulse produced by the solenoid. | 01-30-2014 |
20140037516 | SURFACE PREPARATION - A method of processing a component having a capillary passage, particularly a sample testing device for tests involving capillary flow, comprises passing a treatment fluid through the passage to leave a surface coating on the internal surface of the passage. | 02-06-2014 |
20140112838 | LIQUID HANDLING APPARATUS - A liquid handling apparatus includes a substrate that includes a groove which is a channel through which a liquid can be moved on the basis of a capillary phenomenon, and a film that is bonded to the substrate to cover the opening of the groove, in which the channel has a main channel and a guide channel, the groove has a main groove that is the main channel by the film being bonded to the substrate, and a guide groove that is the guide channel by the film being bonded to the substrate, opens on a lateral surface of the main groove, and has a width narrower than the width of the main groove, and the guide groove is placed in an area on a film side of the lateral surface of the main groove and shallower than the main groove. | 04-24-2014 |
20140219886 | CAPILLARY MICROCUVETTE HAVING DOUBLE LOADING MEANS - The present invention relates to a capillary microcuvette, the microcuvette comprises a body member having two plates and a cavity formed within the body, the cavity being defined by two opposing inner surfaces of the two plates of the body member, a portion of the cavity defining a detection zone, a capillary inlet being provided at one end of the body member that is communicated with the cavity, a sample slot being provided at a portion of the body member in which the capillary inlet is not formed, the sample slot being communicated with the cavity. The present microcuvette improves user convenience by providing dual application means of applying a specimen directly from a fingertip or using a pipette. | 08-07-2014 |
20150125363 | SPECIMEN COLLECTOR FOR COLLECTING A LASER MICRO-DISSECTATE - A laser microdissectate specimen collector for a laser microdissection device includes a collecting chamber configured to receive a dissectate. The collecting chamber has, on a specimen side, an opening open to the environment for receiving the dissectate. The collecting chamber also has a first valve. The first valve, in a closed state thereof, forms a closure of the collecting chamber opposite to the opening for retaining the dissectate. A capillary line is connected downstream of the first valve to the collecting chamber such that the capillary line is configured to transport the dissectate out of the collecting chamber. | 05-07-2015 |
20150298125 | Surface Tension Controlled Valves - The present teachings relate to surface tension controlled valves used for handling biological fluids. The valves controlled by optically actuating an electro-wetting circuit. | 10-22-2015 |
20150343441 | FLUID HANDLING DEVICE - A fluid handling device includes a substrate, a film, and a conductive layer. The substrate includes a first through-hole, and a second through-hole. The conductive layer is disposed on one surface of the film to extend in a first area, a second area and a third area of the film. The substrate includes a first surface and a second surface facing away from the first surface. The first area is bonded to the first surface of the substrate such that a housing part is formed by closing one opening of the first through-hole, and such that a part of the conductive layer is exposed to the inside of the housing part. The second area is disposed inside the second through-hole, and the third area is bonded to the second surface of the substrate such that a part of the conductive layer is exposed to the outside. | 12-03-2015 |
20150360223 | FLUID HANDLING DEVICE - A fluid handling device includes a substrate, a film and a conductive layer. The substrate includes a through hole or a recess. The film includes first, second and third regions. The conductive layer is disposed on one surface of the film across the first, second and third regions. The first region of the film is bonded to one surface of the substrate such that one of openings of the through hole or an opening of the recess is closed to form a housing part, and that a part of the conductive layer is exposed to the inside of the housing part. The second region of the film is bent such that the conductive layer is located on an outside. The third region of the film is bonded to the first region of the film such that the conductive layer is exposed to the exterior. | 12-17-2015 |
20160167043 | DEVICE FOR THE CAPILLARY TRANSPORT OF LIQUIDS, USE AND METHOD FOR PRODUCING SUCH A DEVICE | 06-16-2016 |
20180021026 | SELF-CONTAINED SAMPLING DEVICE FOR PROCESSING WHOLE BLOOD | 01-25-2018 |
20180024155 | DIAGNOSTIC CHIP | 01-25-2018 |