Entries |
Document | Title | Date |
20080200980 | PROFILE REDUCTION OF VALVE IMPLANT - A method for reducing an axial profile of a valve implant includes providing a valve implant having a longitudinal axis and a delivery catheter having a central axis and a distal receiving section. The method further includes helically rolling the valve implant around a rolling axis that is offset at an angle of about 15 degrees to about 60 degrees with respect to the longitudinal axis to form a rolled valve implant having a rolled axis, where the rolled axis is the same as the rolling axis. The method further includes aligning the rolled axis of the rolled valve implant with the central axis of the delivery catheter. The method further includes inserting the rolled valve implant into the distal receiving section of the delivery catheter. | 08-21-2008 |
20080208327 | METHOD AND APPARATUS FOR REPLACING A PROSTHETIC VALVE - In one aspect, the present disclosure concerns a percutaneously delivered adapter stent that is deployed within a previously implanted prosthetic valve and serves as an anchor or platform for implanting a percutaneously delivered replacement valve within the previously implanted valve. The adapter stent can be delivered to the implantation site via the patient's vasculature and positioned within the previously implanted valve. The stent can then be deployed to cause the stent to expand and become anchored to the inner surface of the previously implanted valve. Subsequently, the replacement valve can be positioned within the adapter stent and deployed to cause the replacement valve to expand and become anchored to the adapter stent. The adapter stent and the replacement valve can be mounted on the same catheter for delivery to the implantation site. | 08-28-2008 |
20080208328 | Systems and Methods For Placement of Valve Prosthesis System - Valve prosthesis systems and methods/systems for placement of such valve prostheses are provided that facilitate efficient, reliable and minimally invasive delivery modalities. The placement systems and methods permit remote manipulation and positioning of the valve prosthesis such that desirable placement relative to anatomical structures, e.g., the heart annulus, may be achieved. The valve prosthesis includes a resilient ring, a plurality of leaflet membranes mounted with respect to the resilient ring, and a plurality of positioning elements movably mounted with respect to the flexible ring. The delivery system includes a first elongate element that terminates at the valve prosthesis and is manipulable by an operator to remotely rotate the positioning elements relative to the flexible ring. A second elongate element terminates at the valve prosthesis and is manipulable by an operator to remotely advance the valve prosthesis downward into an anatomical annulus. The second elongate element may be manipulated to remotely advance the valve prosthesis into the anatomical annulus to assume a position for supporting post-implantation function of the valve prosthesis in situ. The first elongate element may be further manipulated to remotely rotate the positioning element relative to the flexible ring to cause the positioning element to engage tissue associated with the anatomical annulus and to thereby maintain the post-implantation position of the valve prosthesis in situ. Methods for valve prosthesis deployment are also provided. | 08-28-2008 |
20080208329 | HANDLE MECHANISM TO ADJUST A MEDICAL DEVICE - An apparatus for adjusting the position and orientation of a medical device within a patient's body includes a distal portion, a body portion and a proximal portion. The distal portion has a lumen for receiving at least three control tubes. Each control tube houses a control wire that is attached to the medical device. The body portion is connected to the distal portion by a ball-and-socket joint and configured to receive at least one control wire. The proximal portion is rotatably and slidably attached to the body portion and configured to receive at least one control wire. | 08-28-2008 |
20080228263 | Delivery systems and methods of implantation for replacement prosthetic heart valves - A delivery system and method for positioning and partially deploying a replacement valve at an implantation site, verifying the location of the replacement valve relative to the implantation site, and retrieving the partially deployed stent for repositioning relative to the implantation site. | 09-18-2008 |
20080234813 | Percutaneous Interventional Cardiology System for Treating Valvular Disease - A system is provided for treating valvular disease percutaneously though a ventricular apex of the heart. The system includes a needle for piercing through the ventricular apex of the heart and creating a hole whereby a catheter can be passed through the skin and the wall of the heart to gain access to the interior of the heart. Once percutaneous access to the heart is obtained, any of a variety of techniques can be utilized for annular and/or valvular therapy and/or repair through the catheter. A closure device is necessary for closing the puncture of the heart. Any of a variety of vascular closure devices can be modified to be utilized with the system to close the puncture of the ventricular apex of the heart. | 09-25-2008 |
20080234814 | Low Profile Heart Valve and Delivery System - Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve. | 09-25-2008 |
20080243245 | Percutaneous Heart Valve Prosthesis - A percutaneous heart valve prosthesis ( | 10-02-2008 |
20080249618 | Repair of Incompetent Heart Valves by Interstitial Implantation of Space Occupying Materials or Devices - Incompetency or regurgitation of a cardiac valve is treated by injecting a space occupying material(s) or implanting a space occupying device(s) at an interstitial location adjacent to the valve such that the space occupying material or device exerts pressure on the valve causing one or more leaflets of the valve to be favorably repositioned. The procedure may be performed by open thoracotomy, thorascopically or transluminally using a tissue penetrating catheter. | 10-09-2008 |
20080249619 | CARDIAC-VALVE PROSTHESIS - A cardiac-valve prosthesis which can be used, for example, as a valve for percutaneous implantation. The prosthesis includes an armature for anchorage of the valve prosthesis in the implantation site. The armature defines a lumen for passage of the blood flow and supports a set of prosthetic valve leaflets, which, under the action of the blood flow, are able to move into a radially divaricated condition to enable the flow of the blood through the lumen in a first direction and a radially contracted condition, in which the valve leaflets co-operate with one another and block the flow of the blood through the prosthesis in the opposite direction. The armature includes, in one embodiment, two annular elements connected by anchor members having the capacity of projecting radially with respect to the prosthesis, and support members for the set of leaflets, the support members being carried by at least one of the annular elements so as to leave substantially disengaged the aforesaid lumen for passage of the blood. | 10-09-2008 |
20080249620 | VALVE HOLDER - A valve holder assembly having a main valve holder and a detachable secondary valve holder for positioning a heart valve prosthesis and a method of implanting a stentless heart valve prosthesis are disclosed. | 10-09-2008 |
20080269876 | Repair of Incompetent Heart Valves by Papillary Muscle Bulking - Incompetency or regurgitation of a cardiac valve is treated by injecting a space occupying material or implanting a space occupying device within a papillary muscle or in heart tissue near a papillary muscle to cause lengthening or repositioning of the papillary muscle in a manner that improves coaptation of the valve leaflets and lessens valvular incompetency or regurgitation. The procedure may be performed by open thoracotomy, thoracoscopically, by a tran-endocardial catheter based approach or by a trans-coronary catheter based approach. | 10-30-2008 |
20080269877 | Systems and methods for valve delivery - A system having an elongate delivery catheter, an elongate mesh body including an expandable region positioned around at least a portion of the elongate delivery catheter, a retractable member that extends through the elongate delivery catheter to connect to the elonga'te mesh body, where the retractable member moves to radially expand the expandable region of the elongate mesh body from an undeployed state to an intermediate state. The system also includes a valve positioned around at least a portion of the elongate delivery catheter position, and a filter positioned around at least a portion of the elongate delivery catheter to filter and control fluid flow. | 10-30-2008 |
20080269878 | MINIMALLY-INVASIVE HEART VALVE WITH CUSP POSITIONERS - A prosthetic heart valve having an internal support frame with a continuous, undulating leaflet frame defined therein. The leaflet frame has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. The leaflet frame may be cloth covered and flexible leaflets attached thereto form occluding surfaces of the valve. The support frame further includes three cusp positioners rigidly fixed with respect to the leaflet frame and located at the outflow end of the support frame intermediate each pair of adjacent commissure regions. The valve is desirably compressible so as to be delivered in a minimally invasive manner through a catheter to the site of implantation. Upon expulsion from catheter, the valve expands into contact with the surrounding native valve annulus and is anchored in place without the use of sutures. In the aortic valve position, the cusp positioners angle outward into contact with the sinus cavities, and compress the native leaflets if they are not excised, or the aortic wall if they are. The support frame may be formed from a flat sheet of Nitinol that is bent into a three-dimensional configuration and heat set. A holder having spring-like arms connected to inflow projections of the valve may be used to deliver, reposition and re-collapse the valve, if necessary. | 10-30-2008 |
20080275549 | IMPLANTABLE PROSTHETIC VALVE WITH NON-LAMINAR FLOW - A valve prosthesis device is disclosed suitable for implantation in body ducts. The device comprises a support stent comprised of a deployable construction adapted to be initially crimped in a narrow configuration suitable for catheterization through the body duct to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location, and a valve assembly comprising a flexible conduit having an inlet end and an outlet, made of pliant material attached to the support beams providing collapsible slack portions of the conduit at the outlet. The support stent is provided with a plurality of longitudinally rigid support beams of fixed length. When flow is allowed to pass through the valve prosthesis device from the inlet to the outlet the valve assembly is kept in an open position, whereas a reverse flow is prevented as the collapsible slack portions of the valve assembly collapse inwardly providing blockage to the reverse flow. The device is configured so that retrograde flow will be altered from laminar flow and directed towards the leaflets to effect closing. The device can be deployed in a native heart valve position using a deployment catheter advanced through a body lumen such as a blood vessel, including an aorta. | 11-06-2008 |
20080281411 | Assembly Comprising A Ring For Attachment In A Passage Surrounded By Body Tissue As Well As An Applicator For Fitting The Ring In The Passage - The present invention relates to an assembly comprising: a ring having anchoring elements for attaching the ring in a passage surrounded by body tissue, in particular blood vessel tissue. An applicator for fitting the ring in the passage; in which the anchoring elements have an anchoring position in which they protrude with respect to the ring, and in which the anchoring elements comprise a memory material, such as a memory metal or memory polymer, and are designed so that they can be bent from an anchoring position counter to a spring force into a fitting position and can be frozen in this fitting position by a temperature treatment in order to bend the anchoring elements back from the fitting position by the effect of this spring force into the anchoring position when a predetermined threshold temperature is exceeded, and in which the applicator is provided distally with a carrier for carrying the ring. The assembly according to the invention is provided with an influencing system for influencing the temperature of the anchoring elements of the ring carried by the carrier in such a way that the anchoring elements bend back from the fitting position to the anchoring position by increasing the temperature of the anchoring elements to above the threshold temperature. | 11-13-2008 |
20080306586 | Minimally Invasive System for Delivering and Securing an Annular Implant - A delivery device for an annular implant is provided, comprising an annular implant having an adjustable dimension; a plurality of movable elongated deployment members, each having a proximal end and a distal end and an annular implant deployment region therebetween; and a distal joining member for joining the distal ends of the deployment members, wherein the deployment members are expandable by an expansion means to a deployment configuration, and the implant deployment regions of the deployment members are substantially parallel in an expanded configuration. The annular implant can comprise an adjustment mechanism in communication with a releasably attached elongated adjustment tool, whereby the size or shape of the annular implant can be incrementally adjusted. | 12-11-2008 |
20090030510 | METHODS AND APPARATUS FOR PERCUTANEOUS AORTIC VALVE REPLACEMENT - A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve comprised of a reversibly expandable occluding means, such as balloons, surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluding means is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve with occluding means substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The ablation stent(s) displace the native valve tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the ablation stent(s) at the aortic annulus with precision and relative ease. Ablation of the native aortic valve removes the structural obstacles to precise PAV placement. The temporary aortic valve mediates the hemodynamic forces upon the devices as encountered by the surgeon following native valve ablation. The temporary valve also promotes patient stability through continuous coronary perfusion and a moderated transvalvular pressure gradient and regurgitation. Sequential delivery of low profile PAV components minimize the risk of trauma and injury to vascular tissues. Mathematical considerations for determining the optimum cross-sectional area for the temporary valve blood perfusion gaps are also described. | 01-29-2009 |
20090054975 | DEPLOYMENT DEVICE FOR CARDIAC SURGERY - A deployment device for deploying a material into a patient, said deployment device having a housing and a placement device including a retracted condition within the housing for holding a material, in a collapsed condition, within the housing and an extended condition from the housing for disposing and releasing the material at a predetermined site in an uncollapsed condition. A method of deploying a material by placing the placement device in an extended condition and affixing the material to the extended placement device, retracting the placement device into the housing with the material in a collapsed condition, extending the placement device, and placing the material at a predetermined site in an uncollapsed condition. | 02-26-2009 |
20090054976 | STENT LOADING TOOL AND METHOD FOR USE THEREOF - A loading tool for withdrawing, crimping, and loading a stent-mounted valve into a delivery catheter, and for pushing the stent-mounted valve from the delivery catheter into a native heart valve orifice. The loading tool comprises at least one connector adapted for being removably connected to the stent of the stent-mounted valve. A crimping tool having a generally converging shape is adapted for use with the loading tool. Following connection of the loading tool to the stent-mounted valve, the loading tool operates to allow the stent-mounted valve to be drawn through the crimping tool, and loaded, in a crimped state, into a delivery catheter. Also disclosed is a kit of the of the various components for effecting the delivery of the stent-mounted valve and a method for withdrawing, crimping, and loading a stent-mounted valve from a storage container into a delivery catheter for the performance of a transcatheter valve implantation procedure. | 02-26-2009 |
20090069886 | PROSTHETIC VALVE DELIVERY SYSTEM INCLUDING RETROGRADE/ANTEGRADE APPROACH - A device for implanting an expandable heart valve prosthesis at a valve annulus in a patient's heart includes an implantation device configured to extend from a first opening in the patient's body, through the patient's aorta, through a valve annulus, through an opening in a ventricle, and to exit through the patient's thoracic region. The device further includes a port having a hemostasis valve for providing access through the patient's thoracic region and into the ventricle and at least two interchangeable modules configured for delivery using the implantation device. | 03-12-2009 |
20090069887 | FLUID-FILLED DELIVERY SYSTEM FOR IN SITU DEPLOYMENT OF CARDIAC VALVE PROSTHESES - An instrument for deploying a cardiac valve prosthesis, including a plurality of radially expandable portions, at an implantation site, includes a plurality of deployment elements each independently operable to obtain the radial expansion of a radially expandable portion of the valve prosthesis. Additionally, the instrument is adapted to provide a de-aired, fluid-filled, or gas filled environment in order to minimize and/or prevent air embolism during the implantation procedure. The fluid can contain a drug. A method for deploying the cardiac valve prosthesis includes advancing the instrument to an implant site and independently actuating the radially expandable portions. | 03-12-2009 |
20090069888 | Mitral Hook - A mitral hook instrument for use particularly in heart valve operations. The mitral hook is used in particular for grasping or hooking secondary chords for lysis procedures. The interior surface of the hook has a groove or channel to facilitate use of a scalpel to cut a chord or other member which has been grasped and exposed by the hook. Also, markings are preferably provided on the distal end of the mitral hook instrument in order to assist the surgeon. | 03-12-2009 |
20090069889 | STREAMLINED, APICAL DELIVERY SYSTEM FOR IN SITU DEPLOYMENT OF CARDIAC VALVE PROSTHESES - A system for implanting a heart valve prosthesis in a patient's heart includes a balloon expandable, tissue, stented heart valve, and an apical valve delivery device for delivering the stented heart valve to a target site in the patient's heart. The delivery device includes an inflation balloon module for expanding the stented heart valve prosthesis, markers on the delivery device to assist in location of the delivery device at an appropriate location, and a streamlined cap. | 03-12-2009 |
20090069890 | STREAMLINED DELIVERY SYSTEM FOR IN SITU DEPLOYMENT OF CARDIAC VALVE PROSTHESES - A system for implanting a heart valve prosthesis in a patient's heart includes a balloon expandable, tissue, stented heart valve and a transfemoral valve delivery device for delivering the stented heart valve to a target site in the patient's heart. The delivery device includes an inflation balloon module for expanding the stented heart valve prosthesis, markers on to assist in location of the delivery device at an appropriate location; and a streamlined cap. | 03-12-2009 |
20090076598 | Everting Heart Valve - The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration. | 03-19-2009 |
20090076599 | Heart valve holder assembly for use in valve implantation procedures - A valve holder assembly for delivering a prosthetic heart valve having a stent base an multiple extending commissure posts. The valve holder assembly includes a holder and a rotor that is rotatable relative to the holder. | 03-19-2009 |
20090093876 | RECOIL INHIBITOR FOR PROSTHETIC VALVE - A valve loading apparatus is provided for loading a crimped prosthetic valve into a lumen of a delivery system. The valve recoil adapter can counteract recoil of a compressed prosthetic valve, and maintain the valve at its desired crimp diameter. An integrated bioprosthesis/delivery system is provided for delivering a bioprosthesis to a target area within a body lumen is provided. The delivery system includes a valve covering member and a compressing member, which compresses the valve covering member to surround, hold, and/or compress the valve during delivery to the target area. | 04-09-2009 |
20090093877 | ACTIVE HOLDER FOR ANNULOPLASTY RING DELIVERY - An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle. | 04-09-2009 |
20090099653 | EXPANDABLE VALVE PROSTHESIS WITH SEALING MECHANISM - A prosthetic heart valve includes at least one sealing member. The sealing member is adapted to conform to any surface irregularities found on the inner surface of the valve annulus, including any calcium deposits formed on the valve leaflets. The sealing member can be self-expanding or non-expanding. When deployed, the sealing member is adapted to create a blood tight seal between the prosthetic heart valve and the inner surface of the valve annulus thereby minimizing and/or eliminating perivalvular leakage at the implantation site. | 04-16-2009 |
20090118825 | METHOD AND APPARATUS FOR IMPROVING MITRAL VALVE FUNCTION - A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation. | 05-07-2009 |
20090125102 | IMPLANTABLE DEVICES FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN - An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like. | 05-14-2009 |
20090132033 | Implant Delivery System and Method - An implant delivery system may comprise a catheter including at least one lumen, a guide wire configured to be received in the lumen, and an implant. The guide wire may comprise a clamping mechanism disposed about a distal end of the guide wire. The clamping mechanism may include a first and at least a second jaw wherein at least one of the jaws is configured to pivot between a closed position wherein the jaws define at least one internal cavity between the jaws configured to receive at least a portion of the implant and an open position configured to release the implant. The implant may be configured to be received in the lumen and may comprise a driver configured to be releasably received in the cavity of the clamping mechanism. | 05-21-2009 |
20090132034 | Bioprosthetic Valve Clip and Handle - An improved implantation holder apparatus and system for holding bioprosthetic aortic valves for insertion into a heart. The handle system interacts with implantation holder and the valve in such a way that commissure support struts may be retracted by simply rotating the handle which allows the surgeon more room to work in tight quarters to complete the implantation process. Included is a handle system, which can be attached and detached, for securing the holder during application of the parachute stitching and moving the valve into position. Once the valve is in position, the handle may be retained in place, or removed for greater ease of access to the aortic cavity. | 05-21-2009 |
20090138079 | PROSTHETIC HEART VALVE FOR TRANSFEMORAL DELIVERY - Apparatus is provided that includes a valve prosthesis for attachment to a native valve complex of a subject. The prosthesis includes a support frame, which is shaped so as to define a plurality of axial support arches, which extend in a radially outward direction, and are configured to apply, regardless of a rotational orientation of the support frame with respect to the native valve complex, an upstream axial force to a downstream side of one or more native structures selected from the group consisting of: native leaflet tips of the native valve complex, and native valve commissures. The support frame is also shaped so as to define an upstream skirt, which is configured to apply a downstream axial force on an upstream side of the native valve complex. The prosthesis further includes a prosthetic heart valve, coupled to a portion of the support frame. Other embodiments are also described. | 05-28-2009 |
20090143857 | TAPERED LOADING SYSTEM FOR IMPLANTABLE MEDICAL DEVICES - Loading systems for compressing and loading an implantable medical device into a device chamber of a medical device delivery system are described. The loading systems include an elongate holding chamber within which the intraluminal medical device is disposed. A plunger has one or more attached pushers adapted to axially advance the intraluminal medical device through an intermediate portion of the holding chamber that has a tapered surface, which compresses the intraluminal medical device over a dilator of a medical device delivery system that has been introduced through the distal end of the elongate holding chamber. The elongate holding chamber can be placed within an outer storage container with an appropriate seal to for storage of the intraluminal medical device within the loading system. Methods of preparing an intraluminal medical device for implantation in a patient and kits useful in such methods are also described. | 06-04-2009 |
20090157174 | SYSTEMS AND METHODS FOR ENABLING HEART VALVE REPLACEMENT - The present invention describes a cardiac prosthetic system ( | 06-18-2009 |
20090171456 | Percutaneous heart valve, system, and method - Devices, systems, and methods are provided to treat diseased cardiac valves. The device includes a percutaneous heart valve having an expandable valve frame including valve frame members, a valve leaflet coupled to the valve frame, and an expandable stent anchoring frame coupled to the valve frame including stent frame members defining a first portion and a second portion having greater flexibility than the first portion, where the first portion and the valve frame define a length, and where the stent frame members and the valve frame members along the length provide a contiguous surface over which a delivery device can repeatedly slide over the length in its entirety in two longitudinal directions when the first portion and the valve frame are in a partially expanded state during delivery from the delivery device. | 07-02-2009 |
20090177275 | SENSING DELIVERY SYSTEM FOR INTRALUMINAL MEDICAL DEVICES - Delivery systems and methods of treatment are described. The delivery systems facilitate visualization, monitoring, or sensing of body vessel parameters, blood parameters, or an intraluminal medical device included in the delivery system prior to, during, or after deployment in a body vessel. A sensing apparatus associated with the delivery systems provide information relating to the body vessel and/or fluid within the body vessel that can be used for verification of placement, confirmation of intraluminal medical device function, and/or determination of the need for additional delivery steps, among other purposes. The information can also be used for verification of initial vessel sizing information. | 07-09-2009 |
20090192600 | Sizing device having two sizers and methods of use - A sizing device for measuring a valve annulus, said sizing device comprising: an elongate segment having first and second ends; a first sizer attached to the first end of the elongate segment; and a second sizer attached to the second end of the elongate segment, wherein the first and second sizers have different shapes that correspond to the same size of valve annulus. A method of measuring a valve annulus of a heart. A system for measuring a valve annulus of a heart. | 07-30-2009 |
20090192601 | Infundibular Reducer Device Delivery System and Related Methods - Described is a delivery system for minimally invasive delivery of a self-expandable stent to a body lumen, and particularly delivery of a prosthetic valve to the right ventricular outflow tract. Also described is a method of loading a stent onto such a delivery system, and a method of delivering a self-expandable stent to a desired anatomic site. | 07-30-2009 |
20090192602 | Deformable Sizer and Holder Devices for Minimally Invasive Cardiac Surgery - Described is a device for sizing a heart valve annulus by a minimally invasive route, the device comprising: a sizing plate having first and second major surfaces, wherein the sizing plate comprises a deformable material such that the sizing plate can deform and fit through the minimally invasive route; and an elongate handle to which the sizing plate is attached. Also described is a similarly deformable device for holding an annuloplasty device. Additionally, methods of using the deformable sizing and holding devices are disclosed. | 07-30-2009 |
20090192603 | Adjustable Sizer Devices for Minimally Invasive Cardiac Surgery - Described is an adjustable device for sizing a heart valve annulus by a minimally invasive route, the device comprising: a cannula comprising a proximal end, a distal end and an interior lumen; and at least one wire extending through the interior lumen of the cannula, wherein the at least one wire may be advanced or retracted through the lumen and from the distal end of the cannula, such that a segment of the wire may form a plurality of different predetermined shapes of predetermined sizes used to size the heart valve annulus. Additionally, methods of using such adjustable sizing devices are disclosed. | 07-30-2009 |
20090192604 | Sizer, Holder and Delivery Devices for Minimally Invasive Cardiac Surgery - Described is a device for delivering a valve annulus sizer or annuloplasty device holder to a heart valve annulus, the device comprising: an elongate shaft comprising a proximal end, a distal end and at least a portion of the shaft being malleable, wherein the distal end of the elongate shaft connects to the sizer or holder. Also described are a sizer device for sizing a heart valve annulus, and a delivery device that releasably attaches a sizer device or a holder device for delivery to and/or from a heart valve annulus. | 07-30-2009 |
20090192605 | Sizer Device Having a Plurality of Anterior-Posterior Ratios - Described is a device for evaluating a heart valve annulus in order to choose a particular annuloplasty device to be attached to the annulus, wherein the annuloplasty device has an inter-trigonal or inter-commissural distance and an anterior-posterior ratio, the device comprising: a valve sizing element having one of a plurality of inter-trigonal or inter-commissural distances and comprising a plurality of indicia on the valve sizing element corresponding to a plurality of anterior-posterior ratios and used to compare to the annulus in order to indicate an anterior-posterior ratio of the annulus. Adjustable devices for evaluating a plurality of anterior-posterior ratios are also described. Also, methods of sizing a patient's heart valve annulus are described. | 07-30-2009 |
20090198322 | Methods And Apparatus For Cardiac Valve Repair - The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment. | 08-06-2009 |
20090198323 | Prosthetic Heart Valve System - A prosthetic heart valve system including a prosthetic heart valve and a deflection device. The deflection device includes a line and a connector assembly including a tensioning component. The line interconnects and passes through free ends of stent posts associated with the heart valve, and is further connected to the tensioning component. The tensioning component is transitionable to a tensioning state in which the line is tensioned to inwardly deflect the stent posts. In this regard, the tensioning component is self-locking relative to the line in the tensioning state, and an entirety of the line extending distal the tensioning device does not extend beyond a stent portion of the heart valve opposite the stent posts. In a preferred embodiment, a holder body is further included, coupled to the heart valve apart from the deflection device. | 08-06-2009 |
20090222082 | Transcatheter Heart Valve Prostheses - The present teachings relate to a heart valve prosthesis. The heart valve prosthesis includes a docking station ( | 09-03-2009 |
20090222083 | MULTI-WINDOW GUIDE TUNNEL - Described herein are devices and methods for delivering implants that comprise multiple coupled anchors. The anchors are secured to tissue using a multi-opening guide tunnel that is configured to releasably retain one or more portions of the implant located between two of the anchors. The releasable retention of one or more intervening portions of the implant maintains the position of the implant and the guide tunnel until the implant is secured to the tissue. The multi-opening guide tunnel permits securement of the multiple anchors without requiring repositioning of the guide tunnel for each anchor. | 09-03-2009 |
20090234445 | Catheter device and associated Medical examination and treatment apparatus as well as associated method - A catheter device for treating a cardiac valve disease, which catheter device has a flexible catheter sheath enclosing a catheter cavity and a catheter-specific module disposed at the proximal end close to the catheter tip for the purpose of transporting and positioning a cardiac valve implant and/or for surgically modeling a cardiac valve, is to be embodied in such a way that the risk associated with a cardiac valve intervention is reduced further in comparison with concepts known and practiced in the prior art. Toward that end at least one sensor for imaging is inventively provided in the region of the catheter tip. | 09-17-2009 |
20090240326 | Implant Delivery and Deployment System and Method - An implant delivery system comprising a catheter including at least one lumen, an implant configured to be received in the lumen, and a latching mechanism configured to be received in the implant. The latching mechanism may be configured to releasably couple the implant to a delivery wire and to transmit a torque through the delivery wire to cause at least a portion of the implant to rotate. The an implant may comprise a shaft, a spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position, a garage configured to couple the spacer to a first end region of the shaft, and at least one anchor mechanism. The garage may define a cavity configured to receive the latching mechanism and to increase rotational and translational stability of the latching mechanism. | 09-24-2009 |
20090254177 | Method and Apparatuses for Deploying Minimally-Invasive Heart Valves - A system for delivering and deploying a self-expandable heart valve to a site of implantation such as the aortic annulus includes a deployment mechanism that engages the valve and regulates the rate of expansion of both the proximal and distal ends thereof. The heart valve may be a rolled-type valve and the deployment mechanism may include a plurality of distal fingers and a plurality of proximal fingers that engage the outer layer of the head valve. Controlled radial movement of the fingers regulates the unwinding of the rolled heart valve. The fingers may be removed prior to inflation of a balloon to fully expand the valve, or the fingers may be repositioned to the inside of the valve for this purpose. The deployment mechanism may include an umbrella structure that forces the rolled valve outward into its fully expanded configuration. Alternatively, a gear shaft that engages one or more gear tracks on the valve may be utilized to regulate expansion of the valve. A stabilization balloon may be used to axially and radially locate the deployment mechanism relative to the site of implantation. Methods of operation of the delivery and deployment mechanism include regulating the rate of self-expansion of the valve and forcing the valve outward into its fully expanded configuration utilizing the same or different means. | 10-08-2009 |
20090259304 | Devices and Methods for Treating Valvular Regurgitation - A system for treating mitral valve regurgitation includes a tensioning device having a plurality of helical anchors and a tensioning filament. One embodiment of the invention includes a method for attaching a tensioning device to the annulus of a mitral valve in a trans-leaflet configuration, and applying a tension force to the tension filament in order to exert force vectors on the annulus, thereby reshaping the mitral valve annulus so that the coaption of the anterior and posterior leaflets of the mitral is improved during ventricular contraction. | 10-15-2009 |
20090259305 | Implantable Prosthetic Holder and Handle - An improved implantation holder apparatus and system for holding bioprosthetic aortic valves for insertion into a heart. The handle system interacts with implantation holder and the valve in such a way that commissure support struts may be retracted by simply rotating the handle which allows the surgeon more room to work in tight quarters to complete the implantation process. Included is a handle system, which can be attached and detached, for securing the holder during application of the parachute stitching and moving the valve into position. Once the valve is in position, the handle may be retained in place, or removed for greater ease of access to the aortic cavity. Once the valve is fully sutured into place the handle may be easily reattached to the holder with an automatic cutting system to cut the sutures and allow the holder to be more easily and safely be retracted from the aorta. | 10-15-2009 |
20090264994 | APPARATUS AND METHODS FOR TREATING TISSUE - Apparatus and methods are provided for thermally and/or mechanically treating tissue, such as valvular structures, to reconfigure or shrink the tissue in a controlled manner. Mechanical clips are implanted over the leaflets of a valve, e.g., in the heart, either alone or after thermal treatment to cause the valve to close more tightly. The clips are delivered by a catheter and may be configured to traverse directly over the valve itself or to lie partially over the periphery of the valve to prevent obstruction of the valve channel. The clips can be coated with drugs or a radiopaque coating. Alternatively, individual anchors with a tensioning element, like a suture, may be used to approximate the valves towards each other. The catheter can also incorporate sensors or energy delivery devices, e.g., transducers, on its distal end. | 10-22-2009 |
20090276037 | Method And Apparatus For Circulatory Valve Repair - An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment, the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation. | 11-05-2009 |
20090276038 | Method and apparatus for tissue connection - A tissue connecting device is provided. The device comprise an elongate delivery device having a lumen, a proximal end, and a distal end. The distal end is configured to engage tissue and advance said device into tissue. At least one anchor deliverable through a lumen of the elongate delivery device. The distal end of the device may be designed to engage tissue upon rotation of the device about its longitudinal axis. | 11-05-2009 |
20090281619 | Low Profile Delivery System for Transcatheter Heart Valve - A heart valve delivery apparatus includes a valve carrying member. A prosthetic valve is crimped onto the valve carrying member at a location that is distal or proximal to the balloon member, thereby providing a smaller profile delivery apparatus. | 11-12-2009 |
20090292353 | SYSTEMS AND METHODS TO CONTROL THE DIMENSION OF A HEART VALVE - The cinching apparatus ( | 11-26-2009 |
20090319037 | RETAINING MECHANISMS FOR PROSTHETIC VALVES - Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support stent is delivered to a position on the surface of the outflow side of a native heart valve of a patient, the support stent defining a support-stent interior. An expandable prosthetic heart valve is delivered into the native heart valve from the inflow side of the native heart valve and into the support-stent interior. The expandable prosthetic heart valve is expanded while the expandable prosthetic valve is in the support-stent interior and while the support stent is at the position on the surface of the outflow side of the heart valve, thereby causing one or more of the native leaflets of the native heart valve to be frictionally secured between the support stent and the expanded prosthetic heart valve. | 12-24-2009 |
20100004739 | TOOLS FOR REMOVAL AND INSTALLATION OF EXCHANGEABLE CARDIOVASCULAR VALVES - Tools for the removal and installation of exchangeable cardiovascular valves. The tools facilitate rapid exchange of a cardiovascular valve member mounted in the aortic position (retrograde exchange) or the mitral position (transapical exchange). | 01-07-2010 |
20100023117 | PAPILLARY MUSCLE POSITION CONTROL DEVICES, SYSTEMS, & METHODS - Papillary muscle position control devices ( | 01-28-2010 |
20100023118 | METHOD AND APPARATUS FOR REPAIRING OR REPLACING CHORDAE TENDINAE - A method and apparatus for performing mitral valve chordal repair on a patient include attaching at least one filament to a mitral valve leaflet and to a papillary muscle. The length of filaments can be adjusted by adjusting tension in a filament or by altering the effective length of a filament by cutting filament strands or by moving an adjustment member along the length of the filaments. | 01-28-2010 |
20100030327 | DEVICE FOR THE IMPLANTATION OF A THERAPEUTIC OR DIAGNOSTIC APPARATUS IN OR ON A MAMMALIAN INTERNAL ORGAN | 02-04-2010 |
20100030328 | Apparatus for Treating a Heart Valve, in Particular a Mitral Valve - An apparatus for treating a heart valve apparatus includes at least two anchoring elements designed to be anchored at the annulus and/or heart wall of the valve to be treated. Each anchoring element has a support surface. At least one linking element includes a central branch and two curved side branches, one of which is designed to be engaged on the support surface of an anchoring element, while the other is designed to be engaged on the support surface of another anchoring element, the linking element then being designed to be pivoted to a position such that the anchoring elements interconnect and in which the ends of the central branch are located in the vicinity of the support surfaces. | 02-04-2010 |
20100036483 | Method and apparatus for improving mitral valve function - A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation. The apparatus is also configured to work in conjunction with an electrical lead for an implantable bi-ventricular pacing device, an electrical lead for an implantable cardio defibrillator, etc. | 02-11-2010 |
20100042208 | Percutaneous Heart Valve - A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to the annular ring, claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws in the second position, and leaflet membranes connected to the annular ring, the body member and/or the legs, the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve is designed such that upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding the heart valve in place. The body member and claws may be integrated into a one-piece design. The heart valve may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart. | 02-18-2010 |
20100049312 | AORTIC VALVE REPLACEMENT - A device for replacement of a bioprosthetic valve having an annulus ( | 02-25-2010 |
20100049313 | PROSTHETIC HEART VALVE AND DELIVERY APPARATUS - Embodiments of the present disclosure provide a prosthetic heart valve and a heart valve delivery apparatus for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic valve through the aorta (i. e., in a retrograde approach) for replacing a diseased native aortic valve. In one embodiment, a self-expanding valve comprises an expandable stent that is shaped to maintain the valve in the aortic annulus against axial without anchors or retaining devices that engage the surrounding tissue. A delivery apparatus for delivering s self-expanding prosthetic valve can be configured to allow controlled and precise deployment of the valve from a valve sheath so as to minimize or prevent jumping of the valve from the valve sheath. | 02-25-2010 |
20100070027 | IMPLANT IMPLANTATION UNIT AND PROCEDURE FOR IMPLANTING THE UNIT - The implant implantation unit ( | 03-18-2010 |
20100082098 | DELIVERY DEVICES AND METHODS FOR HEART VALVE REPAIR - Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device. | 04-01-2010 |
20100100174 | TOOLS, SYSTEMS, AND METHODS FOR REMODELING TISSUE - A tool for remodeling a tissue annulus includes an elongate handle and a reshaping element on a distal end of the handle. The reshaping element may be directable between a first configuration to facilitate direction through a tissue annulus, and a second curved configuration to remodel tissue adjacent the tissue annulus. The tool may be used for treating a tissue annulus within a patient's heart, e.g., by introducing the reshaping element through the tissue annulus, and manipulating the tool to reshape the tissue annulus substantially to a contour of the reshaping element. The reshaping element may support the tissue while a prosthesis is secured to the tissue annulus, or the reshaping element may itself be secured to the tissue annulus and released from the tool. | 04-22-2010 |
20100100175 | Adjustable Height Focal Tissue Deflector - A tissue shaping device adapted to reshape target tissue adjacent to a lumen. In some embodiments, the device includes an expandable and contractable anchor, with the anchor having an adjustable height anchoring portion adapted to engage a wall of the lumen in at least first and second anchor heights, the anchoring portion being further adapted to be changed from the first anchor height to the second anchor height by a substantially proximally or a substantially distally directed actuation force. The invention is also a tissue shaping system including a tissue shaping device and a tool for adjusting the height of an anchor of the device. The invention also includes methods of using such tissue shaping devices and systems. | 04-22-2010 |
20100114306 | CARDIOVASCULAR PROCEDURES - A method for performing cardiovascular and surgical procedures includes providing a conduit in the form of a graft/canula placed using balloon dilatation catheter and providing a fixing mechanism for the graft/canula. At least one opening is formed through a wall of the heart substantially at the apex. The escape of blood is prevented through the use of the fixing mechanism. Each of these steps is performed while the heart is beating. | 05-06-2010 |
20100121433 | RECONFIGURING HEART FEATURES - Among other things, a support for living tissue includes gripping elements to attach to the living tissue and to hold the support securely in place. An annular structure is coupled to the gripping elements. The annular structure adjusts the support between a first configuration for installing the support and a second configuration in which the support is held securely in place after installation. The annular structure is self-supporting in the first and second configurations. | 05-13-2010 |
20100121434 | Medical Devices and Delivery Systems for Delivering Medical Devices - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 05-13-2010 |
20100121435 | PERCUTANEOUS TRANSVALVULAR INTRANNULAR BAND FOR MITRAL VALVE REPAIR - Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy. | 05-13-2010 |
20100137979 | Sinus-engaging Valve Fixation Member - A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses. | 06-03-2010 |
20100145439 | MATERIAL FOR TREATMENT OF A HEART VALVE, IN PARTICULAR A MITRAL VALVE - This material comprises an annuloplasty member ( | 06-10-2010 |
20100152843 | Percutaneous Methods for Creating Native Tissue Venous Valves - Percutaneous methods of forming a venous valve from autologous tissue are disclosed. The methods include percutaneously creating one or two subintimal dissections for forming one or two flaps of intimal tissue. In one method, a puncture element is delivered by a catheter based delivery system to a treatment site where a new venous valve is to be created. The puncture element is deployed to gain access to a subintimal layer of the vein wall. A dilation balloon is than positioned and inflated within the subintimal layer to create a flap and corresponding pocket/sinus in the vein, which than acts as a one-way monocuspid valve in the manner of a native venous valve. In a similar manner, methods of forming new bicuspid venous valves by subintimal dissections are also disclosed. | 06-17-2010 |
20100161042 | IMPLANTATION OF REPAIR CHORDS IN THE HEART - A method is provided, including positioning, at an intraventricular site of a ventricle of a patient, a spool coupled to a first end portion of a longitudinal member and coupling a second end portion of the longitudinal member to a portion of tissue facing a lumen of the ventricle. Other embodiments are also described. | 06-24-2010 |
20100161043 | IMPLANTATION OF REPAIR CHORDS IN THE HEART - Apparatus is provided for adjusting at least one dimension of an implant, including a rotatable structure having first and second openings and a channel extending between the first and second openings. The channel allows passage therethrough of an elongate tool. The second end of the structure has a lower surface having one or more recesses along a circumference thereof. A mechanical element provides a protrusion that is disposed within one of the recesses of the rotatable structure during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure. The mechanical clement comprises a depressible portion coupled to the protrusion disposed in communication with the second opening of the lower surface, and configured to dislodge the protrusion from within the recess in response to a force applied thereto by the elongate tool. Other applications are also described. | 06-24-2010 |
20100161044 | Devices, systems, and methods for reshaping a heart valve annulus - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 06-24-2010 |
20100174362 | Medical Device for Treating A Heart Valve Insufficiency or Stenosis - A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta with a catheter. In an embodiment, the endoprosthesis has a plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a collapsed mode during the process of introducing it into the patient's body and an expanded mode when it is implanted. The endoprosthesis may be introduced into a patient's body and expanded via a catheter. In an embodiment, the catheter has first and second slide mechanisms configured to independently manipulate first and second sleeve elements to sequentially expand the endoprosthesis from the collapsed mode to the expanded mode. | 07-08-2010 |
20100174363 | One Piece Prosthetic Valve Support Structure and Related Assemblies - Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prostheses may be placed in a non-invasive manner, e.g., via trans-catheter techniques. The valve prosthesis may include a support ring, a plurality of leaflet membranes mounted with respect to the support ring, and a plurality of retention clip elements. The support structure is advantageously formed from a tubular member or flat stock of shape memory metal. A delivery system for delivery of a valve prosthesis embodying the disclosed support structure is also disclosed. | 07-08-2010 |
20100179647 | METHODS OF REDUCING EMBOLISM TO CEREBRAL CIRCULATION AS A CONSEQUENCE OF AN INDEX CARDIAC PROCEDURE - There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and/or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector. | 07-15-2010 |
20100179648 | SYSTEM AND METHOD FOR PLACING A PERCUTANEOUS VALVE DEVICE - A system and process for placing a percutaneous valve device in a body lumen at the location of implantation is provided. The placement system and method are simple and enhance the accuracy of the placement of the valve device. Anchors and placement wires or sutures are used to fix the implantation target and guide the device to the implantation site. The system and method are applicable to pre-assembled percutaneous valve devices as well as a modular prosthetic valve device, which modular device is also provided. The modular valve device comprises two or more device modules and is designed to be delivered unassembled and then assembled in the body lumen at or near the site where implantation occurs. The device modules may be assembled before or after the implantation target is fixed with the anchor, and then placed using the placement system in a manner similar to how a pre-assembled percutaneous valve device may be placed in accordance with the invention. | 07-15-2010 |
20100179649 | METHOD AND APPARATUS FOR FINE ADJUSTMENT OF A PERCUTANEOUS VALVE STRUCTURE - The invention provides a device for fine adjustment of a prosthetic valve device and a method of adjusting the position of a prosthetic valve after implantation. The adjustment mechanism includes complementary structures on a valve member and device frame that cooperate to provide relative axial and/or angular motion between the valve member and device frame (and thus the native vessel). The adjustment mechanism of the invention may also include a means for selectively maintaining the relative position of the valve member and device frame. The device and method are particularly applicable for use with a modular prosthetic valve device that is assembled in the body lumen. | 07-15-2010 |
20100185275 | MODULAR PERCUTANEOUS VALVE STRUCTURE AND DELIVERY METHOD - A modular prosthetic valve device for implantation in a patient is disclosed. The valve device is designed as two or more modules to be delivered unassembled and combined into an assembled valve device in the body—e.g., in the body at or near the site where implantation occurs. The two or more modules may be a support structure and a valve assembly. The valve assembly may be formed from two or more valve sections. Because the valve device of the invention is deliverable as modules, it may have a smaller delivery diameter than pre-assembled percutaneous valves and permits use of a delivery device of reduced diameter. Delivering the valve device as modules increases the flexibility of the valve device during delivery, compared to percutaneous valve devices in the art. The invention further provides a system for and method of delivering such a modular valve device and assembling it in vivo. The modules of the valve device may be connected by pull wires for delivery sequentially to or near the implantation site in the body lumen, and then assembled by remote manipulation using the pull wires. The system may further include a temporary valve that may be deployed to maintain valvular function while the device modules are assembled. The temporary valve may be attached to the delivery device and deployed either before or after the support structure is expanded, or the temporary valve may be attached to the support structure and deployed when the support structure is expanded. Various locking mechanisms are provided for attaching the device modules together. | 07-22-2010 |
20100185276 | Devices and Methods for Heart Valve Treatment - Devices and methods for treating heart valves include members that assist the valve in closing during at least a portion of the cardiac cycle. Such devices include members configured to alter the shape of a valve annulus, reposition at least one papillary muscle, and/or plug an orifice of the valve so as to provide a coaptation surface for the valve leaflets. | 07-22-2010 |
20100191326 | APPARATUS AND METHOD FOR IMPLANTING COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES - Apparatus for delivering a prosthetic heart valve into a patient by means that are less invasive than conventional open-chest, open-heart surgery. The prosthetic valve may be collapsed while in a delivery device. When the valve reaches the desired implant site in the patient, the valve can be released from the delivery device, which allows the valve to re-expand to the configuration in which it can function as a heart valve. For example, the delivery device may be constructed to facilitate delivery of the prosthetic valve into the patient via the apex of the patient's heart. | 07-29-2010 |
20100198346 | Method for Guiding a Medical Device - A device and method for valve replacement or valve repair is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding a valve replacement delivery member or a valve repair delivery member within the patient while tracking the position of the delivery member in the patient, positioning the valve replacement member or valve repair member in a desired position to place a valve or repair valve and removing the delivery member from the patient. In one aspect of the invention, a delivery system is provided for percutaneous delivery of a heart valve to a predetermined position in the heart of a patient, where the delivery system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a delivery system is provided for percutaneous repair of a heart valve in the heart of a patient, where the repair system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a method and device are provided that involve imaging a native root using an interoperative technique, then introducing a device that is easily visualized in a chosen imaging modality. | 08-05-2010 |
20100198347 | DEVICE AND METHOD FOR TREATMENT OF HEART VALVE REGURGITATION - In one embodiment, the present invention provides a prosthesis that can be implanted within a heart to at least partially block gaps that may be present between the two mitral valve leaflets. In one preferred embodiment, the prosthesis includes an anchoring ring that expands within the left atrium to anchor the prosthesis and a pocket member fixed to the anchoring ring. The pocket member is positioned within the mitral valve, between the leaflets so that an open end of the pocket member is positioned within the left ventricle. When the mitral valve is open, blood flows past the pocket member, maintaining the pocket member in a collapsed state. When the mitral valve closes, the backpressure of the blood pushes into the pocket member, expanding the pocket member to an inflated shape. The mitral valve leaflets contact the expanded pocket member, allowing the prosthesis to block at least a portion of the openings between the leaflets, thereby minimizing regurgitated blood flow into the left atrium. | 08-05-2010 |
20100217384 | Method For Replacing Native Valve Function Of A Diseased Aortic Valve - Methods for replacing native valve function of a diseased aortic valve are disclosed. In an embodiment, a method for replacing native valve function of a diseased aortic valve in a patient includes: (a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system, (b) guiding the artificial heart valve assembly through the vasculature of the patient, (c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system, (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve, (e) expanding the artificial heart valve assembly in the region of the diseased aortic valve, and (f) withdrawing the catheter system from the patient's vasculature. | 08-26-2010 |
20100222876 | APPARATUSES AND METHODS FOR HEART VALVE REPAIR - A medical device for treating a heart having a faulty heart valve is disclosed. The medical device comprises a ligature including a first anchoring member and a second anchoring member is used. The ligature is percutaneously deployable into a patient with a faulty heart valve wherein the first anchoring member to anchor to a first tissue area of the heart and the second anchoring member to anchor to a second tissue area of the heart. | 09-02-2010 |
20100234940 | Prosthetic Valve Delivery System - A prosthetic valve delivery system for percutaneously delivering and deploying a prosthetic valve within an existing valve is disclosed. The delivery system includes a stented prosthetic valve having a balloon-expandable stent portion with a prosthetic valve disposed therein and at least one self-expanding stent portion. The delivery system further includes a dual balloon catheter having a first balloon on which the stented prosthetic valve is disposed during delivery and a second balloon. Upon delivery within the existing valve, the self-expanding stent portion contacts the existing valve and the first balloon expands the balloon-expandable stent portion to a first diameter such that the stented prosthetic valve is in a first stage deployment configuration. The second balloon then expands the balloon-expandable stent portion to a second diameter, greater than the first diameter, such that the stented prosthetic valve is in a second stage deployment configuration being fully deployed within the existing valve. | 09-16-2010 |
20100249915 | VALVE PROSTHESIS WITH MOVABLY ATTACHED CLASPERS WITH APEX - A valve prosthesis, implantation device, and methods for use are provided. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis. Alternative designs of the devices allow different methods for minimally invasive implantation of a sutureless valve prosthesis, including transapical and transcatheter approaches. Also provided is a delivery device for delivery of a medical prosthesis though minimally invasive means. | 09-30-2010 |
20100249916 | METHODS AND DEVICES FOR TRANSAPICAL DELIVERY OF A SUTURELESS VALVE PROSTHESIS - A method for delivering a sutureless cardiac valve prosthesis using a transapical approach is provided. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis within the native cardiac valve, minimizing the extent of imaging necessary. | 09-30-2010 |
20100249917 | Methods for Delivery of a Sutureless Pulmonary or Mitral Valve - Methods for delivering a sutureless pulmonary or mitral valve prosthesis using a transcatheter approach are provided. The implantation devices utilize movable claspers for both positioning and anchoring the valve prostheses within the native cardiac valve, minimizing the extent of imaging necessary. | 09-30-2010 |
20100249918 | DEVICES AND METHODS FOR DELIVERY OF AORTIC AND MITRAL VALVE PROSTHESES - A valve prosthesis and implantation device, and methods for use are provided. The devices described herein may be used for transcatheter delivery of an aortic valve prosthesis or transapical delivery of a mitral valve prosthesis. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis, reducing the extent of imaging needed during the implantation procedure. | 09-30-2010 |
20100249919 | PRE-SIZED PROSTHETIC CHORDAE IMPLANTATION SYSTEM - A pre-sized prosthetic chordae assembly includes a male attachment unit and a female securing member. The male attachment unit includes a plurality of pre-sized prosthetic chordae fixedly connected to at least one male attachment member and a papillary muscle penetration member that is connected to and extends substantially axial to the at least one male attachment member. The female securing member is for receiving the papillary penetration member. | 09-30-2010 |
20100249920 | RECONFIGURING HEART FEATURES - Among other things, a heart tissue support has a ring-shaped body and gripping elements, each gripping element having a free end that is sharp enough to penetrate heart tissue when pushed against the tissue, and a feature to resist withdrawal of the gripping element from the tissue after the sharp free end has penetrated the tissue. Among other things, a tool to attach a support to a heart valve annulus has splaying elements that spread apart to hold the support in an expanded configuration prior to attachment. Among other things, an apparatus includes polygonal elements connected along corners of the elements to form a ring, the polygonal elements being capable of expanding and contracting, and gripping elements attached to points of the polygonal elements. Among other things, a method includes using a delivery tool to expand a support and a heart valve annulus to one diameter. | 09-30-2010 |
20100249921 | Cardiac Valve Procedure Methods and Devices - Devices and methods for performing intravascular procedures without cardiac bypass include embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have a cannula which provides access for surgical tools for effecting repair of cardiac valves. The cannula may have filters which prevent embolitic material from entering the coronary arteries and aorta. The valve devices may also have a cannula for insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel and operate to prevent blood flow and to permit flow through the valve. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. The prosthetic valves are introduced into the vascular system in a compressed state, advanced to the site of implantation, and expanded and secured to the vessel wall. | 09-30-2010 |
20100280603 | IMPLANTATION OF REPAIR CHORDS IN THE HEART - A method is provided, including advancing a distal end of an inner shall of a delivery tool between leaflets of an atrioventricular valve, of a patient and into a ventricle of the patient. The method further includes, while maintaining the distal end of the inner shaft in place and within the ventricle, proximally withdrawing a surrounding shaft of the delivery tool with respect to the distal end of the inner shaft and toward the leaflets. This surrounding shaft surrounds a portion of the inner shaft. The method additionally includes using the surrounding shaft to engage at least one of the leaflets with at least one leaflet-engaging element. After engaging, the distal end of the inner shaft is proximally withdrawn from within the ventricle. Other applications are also described. | 11-04-2010 |
20100280604 | OVER-WIRE ROTATION TOOL - Apparatus is provided that includes an implant structure, which includes a contracting mechanism, which includes a rotatable structure, arranged such that rotation of the rotatable structure contracts the implant structure. A longitudinal member is coupled to the contracting mechanism. A tool for rotating the rotatable structure is configured to be guided along the longitudinal member, to engage the rotatable structure, and to rotate the rotatable structure in response to a rotational force applied to the tool. Other embodiments are also described. | 11-04-2010 |
20100280605 | DEPLOYMENT TECHNIQUES FOR ANNULOPLASTY RING - An anchor driver is provided that includes a driver head having a flexible ring. An anchor is provided that includes a coupling head, which is shaped so as to define: (a) one or more mating elements that engage mechanical coupling elements of the driver head such that rotation of the mechanical coupling elements rotates the mating elements, which in turn rotate the coupling head, and (b) an outer coupling surface, sized to be inserted into and engage the flexible ring. The anchor also includes a tissue coupling element fixed to the coupling head. The rotation of the mechanical coupling elements causes the tissue coupling element of the anchor to screw itself into tissue, thereby causing separation of: (a) the outer coupling surface of the coupling head from the flexible ring, and (b) the mating elements of the coupling head from the corresponding mechanical coupling elements. Other embodiments are also described. | 11-04-2010 |
20100286767 | ANNULOPLASTY RING WITH INTRA-RING ANCHORING - Apparatus is provided that includes an annuloplasty system for use on a subject. The system includes an annuloplasty ring, which includes a sleeve having a lumen, and at least one anchor, shaped so as to define a coupling head and a tissue coupling element, which tissue coupling element is shaped so as to define a longitudinal axis, and is configured to penetrate cardiac tissue of the subject in a direction parallel to the longitudinal axis. The system further includes an anchor deployment manipulator, configured to be removably positioned within the lumen of the sleeve, and, while so positioned, to deploy the tissue coupling element from a distal end of the deployment manipulator through a wall of the sleeve into the cardiac tissue in the direction parallel to the longitudinal axis of the tissue coupling element and parallel to a central longitudinal axis through the distal end of the deployment manipulator. | 11-11-2010 |
20100286768 | DELIVERY AND RETRIEVAL SYSTEMS FOR COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES - A system for delivering a collapsible and re-expandable prosthetic heart valve into a patient includes a valve support structure ( | 11-11-2010 |
20100286769 | System For Implanting a Valve Prosthesis - A valve prosthesis ( | 11-11-2010 |
20100292782 | DEVICE FOR THE IN SITU DELIVERY OF HEART VALVES - A device for deploying a cardiac valve prosthesis includes at least one constraint member for radially constraining radially expandable annular portions of the valve. The constraint member is actuatable to release the annular formations constrained thereby and permit radial expansion of these annular formations. The constraint member has associated a first, slow-acting actuating mechanism and a second, fast-acting mechanism, adapted to produce relatively slow and fast release of the annular formations constrained thereby. The device may include a first constraint member and second constraint member in the form of telescoping sleeves. The slow-acting actuating mechanism will thus act on the outer sleeve, while the fast-acting mechanism will act on the inner sleeve to produce, respectively, slow and fast release of the annular formations. | 11-18-2010 |
20100292783 | DEVICE FOR SURGICAL INTERVENTIONS - A device for locating an operational unit within a patient's body within the framework of a minimally-invasive surgery intervention includes a shaft having a distal end carrying an operational unit. The device includes an illuminator located at the distal end of the shaft. The illuminator is selectively adjustable to provide a selectively variable lighting field in correspondence with the operational unit. The device may be, for example, a delivery system for a heart valve or a balloon device for post-dilation of such a heart valve once implanted. | 11-18-2010 |
20100292784 | DEVICE FOR THE IN SITU DELIVERY OF HEART VALVES - A device for deploying a cardiac valve prosthesis includes a distal valve holder portion and a shaft extending towards the valve holder portion. The shaft is selectively bendable to a curved shape to vary the spatial orientation of the valve holder portion with respect to the desired implantation site. | 11-18-2010 |
20100292785 | IMPLANT FOR TREATMENT OF A HEART VALVE, IN PARTICULAR A MITRAL VALVE, MATERIAL INCLUDING SUCH AN IMPLANT, AND MATERIAL FOR INSERTION THEREOF - This implant ( | 11-18-2010 |
20100298930 | ACCESS TO THE LEFT ATRIUM AND REDUCTION OF MITRAL VALVE LEAFLET MOBILITY - Disclosed are a method for engaging cardiac valve leaflets, including a) directing a distal end of an elongated catheter body of a leaflet-engaging device into a coronary sinus of a heart, b) passing a first leaflet-engaging component located proximate to the distal end of the elongated catheter body of the leaflet-engaging device through cardiac tissue separating the coronary sinus and a left atrium of the heart to enter a left atrium of the heart, and c) engaging a first cardiac valve leaflet with the first leaflet-engaging component, thereby engaging at least one cardiac valve leaflet. Related apparatus and methods are also described. | 11-25-2010 |
20100298931 | VASCULAR IMPLANT AND DELIVERY SYSTEM - A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant is verified prior to full release. The implant can be at least partially resheathed and repositioned if desired. | 11-25-2010 |
20100305691 | Prosthetic Heart Valves, Scaffolding Structures, and Systems and Methods for Implantation of Same - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. | 12-02-2010 |
20100324668 | Mitral Spacer - A heart valve implant may include a shaft and an anchor configured to be coupled to an end of the shaft. A spacer may be coupled to a portion of the shaft and comprise a plurality of individual segments including a first and at least a second individual segment. The first segment may be coupled to the shaft. The second segment may be coupled to at least a portion of an exterior surface of the first segment and may have at least one cross-section dimension which is greater than an internal cross-sectional dimension of a delivery lumen. Additional segments may be coupled to an inner, adjacent segment. The segments may include a collapsible body portion to facilitate percutaneously delivery through a lumen. The segments may define an outer surface of the spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position. | 12-23-2010 |
20100331971 | Cardiac Valve Downsizing Device And Method - A device for repairing a heart valve comprises a medical device ( | 12-30-2010 |
20100331972 | Unitary Quick Connect Prosthetic Heart Valve and Deployment System and Methods - A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps. | 12-30-2010 |
20100331973 | Device And Method For Improving The Function Of A Heart Valve - A device for improving the function of a heart valve comprises: a support member formed from a shape memory material, and a restraining member providing a restraining action on a course of the support member. The support member may abut one side of the valve conforming to the shape of the valve annulus upon said shape memory material assuming an activated shape while the restraining member restrains the course of the support member. The restraining action is removable for allowing the support member to assume a desired, altered course. The restraining member may be biodegradable to be degraded within a patient or may be detachable from the support member to be withdrawn. The support member according to another embodiment presents a shape change in that an increased cross-section is associated with a shortened length of the support member. The support member according to yet another embodiment has a first and a second activated shape. | 12-30-2010 |
20110004297 | TRANSLUMENAL APPARATUS, SYSTEM, AND METHOD - Methods, apparatus, and systems for altering the configuration of a heart valve. Methods, apparatus, and systems include the use of a cord delivered into the heart by a delivery catheter that can be manipulated by a receiving catheter so as to improve the heart valve function. | 01-06-2011 |
20110004298 | ANNULOPLASTY APPARATUS AND METHODS - An annuloplasty system for repairing a valve in a patient's heart comprises a surgical implant including a member having first and second end portions. The implant member further is configured and/or adapted to form a partial ring along a portion of one of the valve annulae of a patient's heart such as the mitral or tricuspid valve annulus. The implant member is axially elastic such that it can axially expand and contract and includes first and second anchors extending from the end portions of the implant member. The anchors are adapted to anchor the implant in tissue such as the mitral or tricuspid valve annulus. The system can facilitate tissue plication (e.g., of the posterior annulus of the mitral valve or the annulus of the tricuspid valve) and reinforcement of a valve annulus. | 01-06-2011 |
20110009956 | MAGNETIC DOCKING SYSTEM AND METHOD FOR THE LONG TERM ADJUSTMENT OF AN IMPLANTABLE DEVICE - An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. The invention may include an adjustment tool for making the final adjustments to the circumference that locks onto the adjustment means of the device with magnets. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like. | 01-13-2011 |
20110015727 | Annuloplasty Ring and Holder Combination - An annuloplasty ring holder includes an angled post for improved visibility and access by the surgeon. The post may be configured to be adjusted in angle and rotation. The ring holder can include a relatively open lower template, including relatively narrow extending radial arms with short, generally arcuate ring-retaining distal portions. The invention includes placements of suture holes and cutting wells which, in combination with improved suture routing, afford the user improved access to cutting the suture that is used to retain the annuloplasty ring to the holder. Another annuloplasty ring and ring holder combination disclosed includes a generally triangular-shaped ring and a generally T-shaped holder. The ring holder has a base portion forming the top of the T shape and engaging against a first segment of the ring, with a radial arm extending from the base portion and forming the post of the T. The radial arm engages against a junction between two segments of the ring. | 01-20-2011 |
20110015728 | TRANSAPICAL DELIVERY SYSTEM FOR HEART VALVES - A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic annulus in an antegrade fashion through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized. | 01-20-2011 |
20110015729 | TRANSAPICAL DELIVERY SYSTEM FOR HEART VALVES - A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic annulus in an antegrade fashion through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized. | 01-20-2011 |
20110015730 | Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 01-20-2011 |
20110022164 | MEDICAL DEVICE FOR USE IN TREATMENT OF A VALVE - A medical device | 01-27-2011 |
20110022165 | INTRODUCER FOR PROSTHETIC HEART VALVE - The present disclosure concerns embodiments of an introducer that is adapted to facilitate insertion of a prosthetic device, such as a prosthetic heart valve, into a patient's vasculature. In one embodiment, the introducer comprises an elongated body defining a central lumen extending between distal and proximal ends of the body. The introducer body can also have a longitudinally extending gap extending along the length of the body between the distal end proximal ends. The gap in the introducer allows a user to place the introducer around implant sutures by passing the sutures through the gap and into the central lumen. Similarly, the gap allows the introducer to be easily removed from the sutures and/or a delivery device by passing them outwardly through the gap. | 01-27-2011 |
20110022166 | MEDICAL DEVICE FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE A MITRAL VALVE - A medical apparatus positionable in a cavity of a bodily organ (e.g., a heart) may constrict a bodily orifice (e.g., a mitral valve). The medical apparatus may include tissue anchors that are implanted in the annulus of the orifice. The tissue anchors may be guided into position by an intravascularly or percutaneously deployed anchor guiding frame. Constriction of the orifice may be accomplished by cinching a flexible cable attached to implanted tissue anchors. The medical device may be used to approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve in order to move the posterior leaflet anteriorly and the anterior leaflet posteriorly and thereby improve leaflet coaptation and eliminate mitral regurgitation. | 01-27-2011 |
20110029071 | ELONGATED BODY FOR DEPLOYMENT IN A CORONARY SINUS - Coronary sinus ring apparatus, including an elongated body for deployment in a coronary sinus, an aperture in a long side of the body, at least a partial lumen extending from one end of the elongated body to at least the aperture, and a guide within the elongated body positioned and shaped to guide an element inserted along the lumen to the aperture. Apparatus for treating a heart, including a delivery tube sized for and adapted for insertion into a body, a sharp tip adapted to be pushed through cardiac muscle, an elongate tensioning element, and a foldable anchor adapted to couple the elongate tension element to cardiac muscle tissue, wherein the delivery tube encloses one or both of the elongate tensioning element and the foldable anchor. Related apparatus is also described. | 02-03-2011 |
20110040374 | MINIMALLY INVASIVE HEART VALVE REPLACEMENT - A replacement valve for implantation centrally within the orifice of a malfunctioning native heart valve. The valve is designed for minimally invasive entry through an intercostal opening in the chest of a patient and an opening in the apex of the human heart. The replacement valve includes either a separate anchor ( | 02-17-2011 |
20110046725 | METHOD OF IMAGING FOR HEART VALVE IMPLANT PROCEDURE - A method as a workflow for imaging for a heart valve implant procedure includes positioning the patient and an articulated imaging apparatus relative to one another, inducing rapid ventricular pacing in the patient, and imaging a region of the patient's heart to obtain image date for a three-dimensional image. The three-dimensional data is used to construct a three-dimensional image of the region of the patient's heart an the three-dimensional image is displayed for use in the implanting of the replacement heart valve. Optional steps may include obtaining a real time two-dimensional image of the patient's heart and superimposing the real time two-dimensional image with the constructed three dimensional image. The replacement valve is moved into position in the patient's heart during rapid ventricular pacing and breath hold using the superimposed two-dimensional and three-dimensional image information. | 02-24-2011 |
20110046726 | Apparatus for Implanting an Aortic Valve Prosthesis - An apparatus for percutaneously implanting an aortic valve prosthesis includes a pump for pumping oxygenated blood from the left atrium into the descending aorta, during a period of time in which an aortic valve prosthesis is being implanted within a diseased aortic valve. First and second catheters are associated with the pump, and a third catheter has an end which is adapted for insertion into the ascending aorta, and the third catheter has an aortic valve prosthesis associated with another end of the third catheter. | 02-24-2011 |
20110054596 | Method of Delivering a Prosthetic Heart Valve - A method of delivering a prosthetic heart valve to a native valve site within the human vasculature. The prosthetic valve is disposed on a balloon at the end of a balloon catheter. The balloon catheter passes through a delivery sleeve assembly. A pull wire travels from the handle to a distal end of the delivery sleeve assembly. Actuation of the handle pulls on the pull wire, which causes the delivery sleeve assembly to bend for facilitating navigation through a patient's vasculature. A stretchable cover is preferably placed over the slotted tube for biasing the steerable catheter toward a straight position. Once advanced to the vicinity of the native valve site, the prosthetic valve may be accurately positioned by advancing the balloon catheter relative to the delivery sleeve assembly and then deployed within the native valve site by inflating the balloon. In an alternative embodiment, the delivery sleeve assembly may be used to advance a self-expanding prosthetic heart valve through a patient's vasculature and a pusher member may be used to eject the prosthetic valve at the native valve site. | 03-03-2011 |
20110060404 | SURGICAL DELIVERY DEVICE AND METHOD OF USE - A delivery device for a stented heart valve comprises a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing. | 03-10-2011 |
20110060405 | VENOUS VALVE APPARATUS, SYSTEM, AND METHOD - A venous valve apparatus, system and method for valve replacement. The valve includes a valve frame, a valve leaflet joined to the valve frame, and a support frame. The valve leaflet includes surfaces defining a reversibly sealable opening for unidirectional flow of a liquid. The support frame meets the valve frame on an axis, where the valve frame and the support frame extend from the axis in an opposing direction. The system further includes a catheter, where the valve can be reversibly joined to the catheter at a location between a proximal end and a distal end of the catheter. The system can be used to deploy the valve from the catheter at a predetermined location. | 03-10-2011 |
20110066231 | IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. | 03-17-2011 |
20110066232 | BIOPROSTHETIC VALVE HOLDER AND HANDLE WITH CUTTING MECHANISM AND METHOD OF USING SAME - A surgical apparatus for use with a prosthetic holder to which a prosthesis is secured by sutures. The apparatus includes an elongated handle having a grip end and a coupler end and defining a first aperture extending along a length from the grip end to the coupler end. The apparatus can also include a first shaft at least partially disposed within the first aperture with a first actuator at the grip end and a holder coupling mechanism at the coupler end. The apparatus can have one of a second shaft and a sheath disposed along the handle with a second actuator at the grip end and a cutting element at the coupler end. A force applied to the first actuator enables one of engagement and disengagement with the prosthesis holder, and a force applied to the second actuator enables deployment of a cutting element to cut the sutures securing the prosthesis to the prosthetic holder. | 03-17-2011 |
20110066233 | METHODS, SYSTEMS AND DEVICES FOR CARDIAC VALVE REPAIR - Disclosed are devices and methods for treating regurgitation through a valve in the heart. The devices can include an expandable, fluid-tight bladder configured to be deployed between valve leaflets of the heart valve. The bladder can include an upper portion that extends into the atrium of the heart; a lower portion that extends into the ventricle of the heart; and a middle portion positionable within the line of valve leaflet coaptation that provides a sealing surface for one or more of the leaflets. | 03-17-2011 |
20110066234 | Percutaneous Mitral Valve Annuloplasty Delivery System - The invention is a tissue shaping system, including a tissue shaping device with an expandable anchor and a lock; a delivery catheter; a delivery mechanism adapted to deliver the tissue shaping device from outside a patient to a target site within a lumen within the patient via the delivery catheter; and an actuator adapted to deliver an actuation force to the lock to lock the anchor in an expanded configuration. The invention is also a system adapted to percutaneously deliver and deploy a tissue shaping device at a target site within a lumen of a patient. The system includes: a handle; a delivery mechanism supported by the handle and adapted to deliver the tissue shaping device from outside the patient to the treatment site via a delivery catheter; and an actuator supported by the handle and adapted to deliver an actuation force to lock an anchor of the tissue shaping device in an expanded configuration. | 03-17-2011 |
20110071623 | METHODS FOR DEPLOYING A PROSTHESIS - The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The disclosure also includes a mounting tool for mounting the prosthesis onto a loading tool, the loading tool useful for loading the prosthesis onto a device for delivering the prosthesis into the patient's heart. Control devices and methods for using these devices are also disclosed. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation. | 03-24-2011 |
20110071624 | DEVICES FOR RETRIEVING A PROSTHESIS - The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The disclosure also includes a mounting tool for mounting the prosthesis onto a loading tool, the loading tool useful for loading the prosthesis onto a device for delivering the prosthesis into the patient's heart. Control devices and methods for using these devices are also disclosed. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation. | 03-24-2011 |
20110082538 | MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE - A device, kit and method may include or employ an implantable device (e.g., annuloplasty implant) and a tool operable to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). The tissue anchors may be guided into precise position by an intravascularly or percutaneously deployed anchor guide frame of the tool and embedded in an annulus of the orifice. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or via a anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in an unanchored, generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve, to move the posterior leaflet anteriorly and the anterior leaflet posteriorly, thereby improving leaflet coaptation to eliminate mitral regurgitation. | 04-07-2011 |
20110082539 | MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT - A minimally invasive method of implanting a prosthetic aortic valve includes forming a surgical site within a patient's chest that includes a first access port, a second access port, a viewing port and a delivery port. A camera is inserted into the viewing port. The native aortic valve leaflets may each be grasped and removed via tools inserted through the first and second access ports. The prosthetic aortic valve may be delivered through the delivery port to the valve annulus using a delivery device. The prosthetic aortic valve is implanted at the valve annulus and the delivery device is withdrawn. A surgeon may perform the remotely operated steps while viewing images provided by the camera. | 04-07-2011 |
20110087322 | Method of Treating Aortic Stenosis Using an Implantable Prosthetic Valve - A method of implanting a prosthetic valve in a stenosed aortic valve via a catheterization technique. A balloon catheter is advanced into a patient's vasculature and a balloon is expanded within the stenosed aortic valve to push aside the calcified leaflets. The prosthetic valve is then introduced into a patient's vasculature through an 18 French arterial introducer. After advancement through the femoral artery and aorta, the prosthetic valve is radially expanded for implantation in the dilated aortic valve. The prosthetic valve includes a compressible and expandable frame and a valvular structure made with pericardial tissue. The prosthetic valve further includes an internal cover fastened to an internal surface of the frame between an inlet end of the frame and the valvular structure. | 04-14-2011 |
20110093062 | INFLATABLE MINIMALLY INVASIVE SYSTEM FOR DELIVERING AND SECURING AN ANNULAR IMPLANT - A delivery device for an annular implant that includes a balloon expansion mechanism and an annular implant having an adjustable dimension. The balloon expansion mechanism includes an inflation tube attached to a non-occluding balloon collar which is supported by trusses radially extending from a trocar. The annular implant further includes a flexible ring core, contiguous coiled spacers, and anchoring blocks. The flexible ring core is adjusted via a cinching mechanism. The anchoring blocks are spaced along the ring core by the contiguous coiled spacers, which keeps the distance between each pair of anchoring blocks equidistant as the ring core diameter is manipulated by the device user. The annular implant can also include gunbarrel elements housed in the trocar. Each gunbarrel element contains a gunbarrel pusher which drives an attachment element into the annular implant and annular tissue. | 04-21-2011 |
20110093063 | Sequential Heart Valve Leaflet Repair Device - A heart valve and tissue repair device for independently, selectively and sequentially grasping heart valve leaflets and independently, selectively and sequentially applying one or more fasteners thereto is disclosed. The device includes a leaflet engaging tip having one or more graspers capable of individually and sequentially grasping leaflets, and one or more deployable fasteners capable of fastening the leaflets. An actuation system for the device individually and selectively controls the graspers and deploys the one or more fasteners. Vacuum pressure from an external vacuum source can be used to grasp the leaflets via a selector system that controls the actuation system so as to individually and sequentially apply vacuum force to the graspers. | 04-21-2011 |
20110093064 | HEART VALVE HOLDER FOR USE IN VALVE IMPLANTATION PROCEDURES - A valve holder for a prosthetic valve having a stent with a stent base and multiple commissure posts projecting from the stent base, the valve holder including a central base portion, a plurality of legs radially extending from the central base portion, each leg comprising a first prong portion spaced from a second prong portion by a gap distance, a plurality of commissure post engaging members, wherein one commissure post engaging member is slideably engaged with each of the plurality of legs, and a handle extending from the central base portion. | 04-21-2011 |
20110098805 | TRANSCATHETER VALVE DELIVERY SYSTEMS AND METHODS - Delivery devices and methods for percutaneously delivering a prosthetic valve to the heart of a patient. These prosthetic valves may be configured to provide complimentary features that promote optimal placement of the prosthetic valve in a native heart valve, such as the aortic valve, mitral valve, pulmonic valve, and/or tricuspid valve. The delivery device includes a release sheath assembly housed within an outer delivery sheath. A release sheath component of the assembly captures a portion of the prosthetic valve to the delivery device, and effectuates complete release of the prosthetic valve with retraction of the outer sheath. | 04-28-2011 |
20110106245 | APPARATUS FOR GUIDE-WIRE BASED ADVANCEMENT OF A ROTATION ASSEMBLY - Apparatus is provided for use with at least one tissue-adjustment device, including a tissue-engaging element having a distal portion configured to engage at least a first portion of tissue of a patient, and having a proximal portion. At least one docking station is coupled to the proximal portion of the tissue-engaging element and is configured to be coupled to the at least one tissue-adjustment device. The docking station includes a locking mechanism configured to lock the tissue-adjustment device to the tissue-engaging element. At least one guide member is reversibly coupled to the at least one docking station and is configured for facilitating slidable advancement of the at least one tissue-adjustment device toward the tissue-engaging element. Other applications are also described. | 05-05-2011 |
20110106246 | TRANSAPICAL DELIVERY DEVICE AND METHOD OF USE - A delivery device for a stented heart valve comprises a handle, an inner catheter shaft extending from the handle and having an enlarged bumper element at a distal end, an outer catheter shaft extending from the handle and slidably coupled around the inner catheter shaft, and a retraction mechanism for controlling longitudinal movement of the outer catheter shaft relative to the inner catheter shaft. The outer catheter shaft includes a generally cylindrical housing at a distal end that is structured to receive the bumper element therein. | 05-05-2011 |
20110112631 | TRANSAPICAL DELIVERY SYSTEM WITH VENTRUCULO-ARTERIAL OVERLFOW BYPASS - Apparatus is provided for implanting a prosthetic device ( | 05-12-2011 |
20110112632 | METHOD OF IMPLANTING A PROSTHETIC VALVE IN A MITRAL VALVE WITH PULMONARY VEIN ANCHORING - A method of implanting a prosthetic mitral valve assembly is disclosed. The prosthetic mitral valve assembly includes a stent and valve combination. The prosthetic mitral valve assembly is provided with an anchoring portion adapted to be positioned in the left atrium. In one embodiment, the anchoring portion includes at least one anchoring arm sized for placement in a pulmonary vein. The stent is radially expandable so that it can expand into position against the walls of the left atrium and accommodate a wide range of anatomies. Contact between the stent and the native tissue in the left atrium reduces paravalvular leakage and prevents migration of the stent once in place. | 05-12-2011 |
20110112633 | DELIVERY/RECOVERY SYSTEM FOR SEPTAL OCCLUDER - A delivery/recovery system to allow an operator to deploy and recover a medical implant, such as an occluder for closing a patent foramen ovale (PFO). In one embodiment, the system includes a delivery mandrel for preventing the occluder from moving in the proximal direction, a delivery wire for securing the occluder to the delivery mandrel and preventing unwanted movement in the distal direction, and a sheath for enveloping the delivery wire, mandrel and occluder. By moving the sheath relative to the occluder in a series of steps, the occluder opens first on a distal side and then on a proximal side, in a manner that holds the occluder in place. | 05-12-2011 |
20110118829 | Attachment device and method - A ventricular assist system and a method of implanting the system are disclosed. The system can have a pump, an inflow conduit, an outflow conduit, and attachment ring and a valvular structure. The attachment ring can be attached to the apex of the heart. The valvular structure can have a flexible, one-way valve in a rigid housing. The inflow conduit can be passed through the valvular structure and the attachment ring into a beating heart with minimal loss of blood. | 05-19-2011 |
20110118830 | System For Replacing Native Valve Function Of A Diseased Aortic Valve - Methods for replacing native valve function of a diseased aortic valve are disclosed. In an embodiment, a method for replacing native valve function of a diseased aortic valve in a patient includes: (a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system, (b) guiding the artificial heart valve assembly through the vasculature of the patient, (c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system, (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve, (e) expanding the artificial heart valve assembly in the region of the diseased aortic valve, and (f) withdrawing the catheter system from the patient's vasculature. | 05-19-2011 |
20110125256 | Slitting Tool - A slitting tool can be used to make a linear incision. The slitting can include a flat blade contained within a housing, and an actuator for extending the flat blade out of a housing. | 05-26-2011 |
20110137408 | Method and System For Cardiac Valve Delivery - The invention provides methods and systems for introducing a delivery device in the heart at or near the apex of the heart, wherein the delivery device includes a prosthesis, advancing the prosthesis to the target site, and disengaging the prosthesis from the delivery device at the target site for implantation. Specifically, the present invention provides valve replacement systems for delivering a replacement heart valve to a target site in or near a heart. The valve replacement system comprises a trocar or other suitable device to penetrate the heart at or near the apex of the heart, a delivery member that is movably disposed within the trocar, and a replacement cardiac valve disposed on the delivery member. The delivery member may further comprise mechanical or inflatable expanding members to facilitate implantation of the prosthetic valve at the target site. | 06-09-2011 |
20110137409 | PROSTHETIC HEART VALVE HAVING FLARED OUTFLOW SECTION - Expandable, percutaneously deployable, prosthetic heart valves and systems for minimally invasive replacement of damaged or diseased native aortic valves comprise an expandable, tubular stent body and a unidirectional valve assembly. Embodiments of the stent body comprise an annulus anchoring section, a sinus section, and an outflow section, with the outflow section flared outward from the sinus section in an expanded configuration. Embodiments of the stent body are self-expanding, comprising, for example nitinol. The valve assembly disposed within the sinus section of the stent body and sutured thereto. Embodiments of the valve assembly comprise three leaflets, each leaflet comprising a curved outer edge sutured to the sinus section of the stent body, and a coapting free edge. Embodiments of the valve leaflets comprise pericardium, for example, porcine pericardium. Embodiments of the prosthetic heart valve have a contracted configuration dimensioned for percutaneous delivery thereof. | 06-09-2011 |
20110144742 | Expansion Device for Treatment of Vascular Passageways - A delivery system for delivering an expandable member to a treatment location includes an elongate shaft and an expandable member coupled to a distal end of the elongate shaft. The expandable member is moveable between a collapsed configuration and an expanded configuration, and has an inner expandable member and a plurality of outer expandable members that at least partially surround the inner expandable member. | 06-16-2011 |
20110144743 | TREATMENTS FOR A PATIENT WITH CONGESTIVE HEART FAILURE - The invention is directed to two minimally invasive therapeutic procedures, particularly for patients with congestive heart failure, and devices and systems for such procedures. One procedure involves providing a valved passageway through the patient's left ventricular wall at the apex of the patient's heart and advancing instruments through the valved passageway to connect the valve leaflets of the patient's heart valve, e.g. the mitral valve, in a “Bow-Tie” configuration to prevent or minimize regurgitation through the valve. The second procedure involves advancing a pacing lead and a pacing lead implanting device through a trocar in the patient's chest and implanting the pacing lead on an exposed epicardial region of the patient's heart wall. The pacing lead has a penetrating electrode which is secured within the heart wall. One or both procedures may be performed on a patient with CHF. | 06-16-2011 |
20110160846 | TRANSLUMENALLY IMPLANTABLE HEART VALVE WITH FORMED IN PLACE SUPPORT - A cardiovascular prosthetic valve, the valve comprising an inflatable cuff comprising at least one inflatable channel that forms, at least in part, an inflatable structure, and a valve coupled to the inflatable cuff, the valve configured to permit flow in a first axial direction and to inhibit flow in a second axial direction opposite to the first axial direction, the valve comprising a plurality of tissue supports that extend generally in the axial direction and that are flexible and/or movable throughout a range in a radial direction. | 06-30-2011 |
20110160847 | APPARATUS FOR DELIVERY AND DEPLOYMENT OF AN EXPANDABLE STENT WITHIN A BLOOD VESSEL - An improved apparatus for delivering and deployment of an expandable stent with a protection sheath within a blood vessel is provided. The system comprises a fluid pressure device which is coupled with a retraction device for the protection sheath such that after retraction of the protection sheath the stent is automatically deployed by the fluid pressure device. The advantage of the invention is an easy and simple operation of the apparatus. | 06-30-2011 |
20110160848 | METHODS FOR CROSSING A HEART VALVE - The present invention provides for methods of using guide wires adapted for passage across a heart valve. The guide wires have an increased diameter and a shorter, relatively floppy distal tip; the increased diameter providing improved pushability to facilitate positioning in a blood jet and passage through a heart valve. The distal tip comprises a section of rectangular cross-section that, in conjunction with the decreased tip length, causes the distal tip to vibrate, or “dance”, when positioned within a blood jet at the outlet of a heart valve. This vibratory motion may be used to position the distal tip within the blood jet, thus facilitating passage through the valve without damage to leaflets of the valve or emboli generation. | 06-30-2011 |
20110172764 | Transcorporeal delivery system and method - Transcorporeal delivery system and method for valve replacement surgery that is minimally invasive. | 07-14-2011 |
20110178596 | CARDIAC VALVE LEAFLET ATTACHEMENT DEVICE AND METHODS THEREOF - A medical device system comprising a guide catheter and a leaflet fastening applicator, the guide catheter having suitable dimensions for deployment and insertion percutaneously into a human heart in a vicinity of a heart valve, the leaflet fastening applicator having a size allowing insertion through the guide catheter and being capable of holding portions of opposing heart valve leaflets, wherein the fastening applicator comprises a pair of grasping-electrodes adapted for holding and engaging the portions of opposing heart valve leaflets together and for applying energy to fasten the portions, in which heart valve leaflets can be captured and securely fastened, thereby improving coaptation of the leaflets and improving competence of the valve. | 07-21-2011 |
20110196480 | POST-OPERATIVE ADJUSTMENT TOOL, MINIMALLY INVASIVE ATTACHMENT APPARATUS, AND ADJUSTABLE TRICUSPID RING - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. | 08-11-2011 |
20110202127 | Apparatus and Methods for Creating a Venous Valve From Autologous Tissue - An implantable prosthesis for percutaneous placement within a vein that forces opposing portions of the vessel wall of a vein together to create a new valve of autologous vein tissue to be operable to alternate between a valve closed configuration and a valve open configuration. When in a preset closed configuration, the implantable prosthesis pushes or pulls portions of the vessel wall of the vein together to substantially close the vein lumen and prevent retrograde blood flow from backflowing through the new valve in the valve closed configuration. The implantable prosthesis has leg portions that may be pushed apart in response to antegrade blood flow through the vein to allow the new valve to achieve the valve open configuration. | 08-18-2011 |
20110202128 | Distal Tip Assembly for a Heart Valve Delivery Catheter - A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter. | 08-18-2011 |
20110208295 | IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. | 08-25-2011 |
20110208296 | Catheter Assembly with Valve Crimping Accessories - Catheter assemblies including a handle assembly located on the proximal end of the catheter assembly and a distal tip assembly located on the distal end of the catheter assembly. A crimping funnel is slidably positioned along the catheter. The crimping funnel includes a distal end having a first diameter and a proximal end having a second diameter smaller than the first diameter. An axial split is formed in the proximal end. A first collar is provided encompassing a portion of the proximal end. The first collar is configured to hold the axial split in the proximal end together when the first collar is at a first axial location along the proximal end, and to allow the axial split in the proximal end to open when the first collar is at a second axial location along the proximal end, such that the crimping funnel can be removed from the catheter assembly. Various methods of retaining a prosthetic valve on the catheter assembly during the crimping process are described. | 08-25-2011 |
20110213459 | SYSTEMS AND METHODS FOR TRANSCATHETER AORTIC VALVE TREATMENT - Devices and methods are configured to allow transcervical or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure. | 09-01-2011 |
20110218619 | LOW-PROFILE HEART VALVE AND DELIVERY SYSTEM - Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed. | 09-08-2011 |
20110218620 | Retaining Mechanisms for Prosthetic Valves - Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native leaflets of a valve. A locking member is used to couple both ends of the support member, forming a support band. An expandable prosthetic heart valve is delivered into the native heart valve and expanded while the expandable prosthetic valve is at least partially within the support band, thereby causing one or more of the native leaflets of the native heart valve to be frictionally secured between the support band and the expanded prosthetic heart valve. | 09-08-2011 |
20110218621 | Method Of Replacing Native Heart Valve Tissue - A device for repairing a heart valve comprises an implantation instrument. The implantation instrument comprises a first support ring, and a second support ring connected to said first support ring to form a coiled configuration. The first support ring is configured to abut one side of the valve and the second support ring is configured to abut an opposite side of the valve to thereby trap a portion of the valve tissue therebetween. The device further comprises an annuloplasty implant adapted to be attached to the heart valve annulus in order to reshape the annulus and allow the leaflets to open and close properly. The annuloplasty implant is connected to the implantation instrument for insertion to the annulus. | 09-08-2011 |
20110224784 | MEDICAL DEVICE SUITABLE FOR USE IN TREATMENT OF A VALVE - A medical device ( | 09-15-2011 |
20110238164 | Device and Method for Placing and Positioning a Heart Valve - A positioning tool comprises an elongate positioning member having a first end and a second end, a tubular positioning body coupled to the first end of the elongate positioning member and including a first end, a second end, and an attachment structure disposed within an open center of the positioning body, and a plurality of pairs of alignment apertures, each pair of alignment apertures including a first alignment aperture adjacent to the first end of the positioning body and a second alignment aperture adjacent to the second end of the positioning body. | 09-29-2011 |
20110238165 | SURGICAL DEVICE FOR CONNECTING SOFT TISSUE - The invention comprises a surgical instrument including an external tube ( | 09-29-2011 |
20110238166 | METHOD FOR DIRECT IMPLANTATION OF A HEART VALVE PROSTHESIS - A method for implanting a heart valve into a patient's heart can include inserting the heart valve prosthesis into a barrel of an implanter apparatus, such that the heart valve prosthesis has a reduced cross-sectional dimension relative to a fully expanded cross-sectional dimension of the heart valve prosthesis. An opening is created in muscle tissue of the patient's heart to provide a substantially direct path that extends from the opening to a desired implantation site in the heart. A length of the barrel is inserted through the opening in the tissue such that an end of the barrel and the opening are along the direct path to the implantation site. The heart valve prosthesis is advanced through the barrel to the implantation site. The heart valve prosthesis is positioned at the desired implantation site. The heart valve prosthesis can be expanded at the desired implantation site from the reduced cross-sectional dimension toward the expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the heart valve prosthesis relative to the adjacent tissue. | 09-29-2011 |
20110245917 | Transcatheter Prosthetic Heart Valve Delivery System With Recapturing Feature and Method - A delivery system for percutaneously deploying a stented prosthetic heart valve. The system includes a delivery capsule and a recapture assembly. The capsule is configured to compressively retain the prosthesis. The recapture assembly includes a frame and sleeve attached to the frame. The recapture assembly is transitionable from a compressed arrangement to an expanded arrangement with a distally increasing diameter. | 10-06-2011 |
20110245918 | REPOSITIONABLE ENDOLUMINAL SUPPORT STRUCTURE AND ITS APPLICATIONS - An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen. | 10-06-2011 |
20110251679 | Transcatheter Prosthetic Heart Valve Delivery System and Method With Stretchable Stability Tube - A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft, a delivery sheath, stability tube, and a handle. The delivery sheath is slidably disposed over the inner shaft, and includes a capsule compressively containing the prosthesis over the inner shaft. The stability tube is coaxially received over the delivery sheath, and includes a distal region. A circumferential rigidity of the capsule is greater than a circumferential rigidity of the distal region. In transitioning from a delivery state to a deployed state, the capsule is withdrawn from the prosthetic heart valve and at least partially into the distal region to permit the prosthesis to self-deploy. The capsule forces the distal region to stretch and expand in diameter. | 10-13-2011 |
20110251680 | Transcatheter Heart Valve Delivery System With Reduced Area Moment of Inertia - A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis. | 10-13-2011 |
20110251681 | Transcatheter Prosthetic Heart Valve Delivery System with Recapturing Feature and Method - A delivery system for percutaneously deploying a prosthetic heart valve. The system includes an inner shaft assembly, a delivery sheath capsule and a handle maintaining a first actuator and a second actuator. The capsule is configured to compressively retain the prosthetic heart valve over the inner shaft assembly. The first actuator is operated to proximally retract the delivery sheath capsule and expose the prosthetic heart valve relative to the capsule. The second actuator is operated to proximally retract the prosthetic heart valve by transmitting forces to the inner shaft assembly. | 10-13-2011 |
20110251682 | Transcatheter Prosthetic Heart Valve Delivery System With Funnel Recapturing Feature and Method - A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment. | 10-13-2011 |
20110251683 | Transcatheter Prosthetic Heart Valve Delivery Device with Stability Tube and Method - A device for percutaneous delivery of a stented prosthetic. heart valve. The device includes a sheath, a handle, and an outer stability tube. The sheath includes a distal capsule and a proximal shaft. The handle has a housing maintaining an actuator mechanism that is coupled to the shaft. The actuator mechanism is configured to selectively move the shaft, and thus the capsule, relative to the housing. The stability tube is coupled to the housing and is coaxially received over the shaft such that the shaft is slidable relative to the stability tube. In a delivery state, the capsule encompasses the prosthetic valve. In a deployed state, the capsule is withdrawn from the prosthetic valve. The shaft slides relative to the stability tube in transitioning from the loaded state to the deployed state. When used with an introducer device, the stability tube frictionally isolates the sheath. | 10-13-2011 |
20110251684 | DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS - Implants or systems of implants and methods apply an upward and inward force producing a minor axis force projection vector within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 10-13-2011 |
20110257733 | Transcatheter Prosthetic Heart Valve Delivery System and Method with Expandable Stability Tube - A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft assembly, a delivery sheath assembly, an outer stability tube, and a handle. The sheath assembly is slidably disposed over the inner shaft, and includes a capsule and a shaft. The capsule compressively contains the prosthesis over the inner shaft. The stability tube is slidably disposed over the delivery sheath, and includes a distal region configured to be radially expandable from a first shape having a first diameter to a second shape having a larger, second diameter. In a first delivery state, the distal region assumes the first shape, providing a low profile appropriate for traversing a patient's vasculature. In a second delivery state, the distal region has the expanded diameter second shape, sized to receive the capsule, such as when retracting the capsule to implant the prosthesis. | 10-20-2011 |
20110257734 | COLLAPSIBLE/ EXPANDABLE PROSTHETIC HEART VALVE DELIVERY SYSTEM AND METHODS - A system for delivering a medical implant includes an expandable member at least partially positioned inside the medical implant and operable to radially expand at least a portion of the medical implant to an expanded condition, first and second grasping mechanisms each adapted to grasp a portion of the medical implant, and a displacement mechanism operatively coupled to the first and second grasping mechanisms and configured to move the first and second grasping mechanisms between an inner position in which the first and second grasping mechanisms are relatively close to one another, and an outer position in which the first and second grasping mechanisms are relatively distant to one another. The movement of the first and second grasping mechanisms from the outer position to the inner position at least partially collapses the medical implant from the expanded condition to enable the medical implant to be repositioned if necessary. | 10-20-2011 |
20110257735 | SYSTEMS AND METHODS FOR DELIVERING A MEDICAL IMPLANT - The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system. | 10-20-2011 |
20110257736 | Flexible Heart Valve and Holder Therefor - A highly flexible tissue-type heart valve is disclosed having a structural stent in a generally cylindrical configuration with cusps and commissures that are permitted to move radially. The stent commissures are constructed so that the cusps are pivotably or flexibly coupled together at the commissures to permit relative movement therebetween. The stent may be cloth-covered and may be a single element or may be made in three separate elements for a three cusp valve, each element having a cusp portion and two commissure portions; adjacent commissure portions for each pair of adjacent stent element combining to form the stent commissures. If the stent has separate elements their commissure portions may be pivotably or flexible coupled, or may be designed to completely separate into independent leaflets at bioresorbable couples. The cloth covering may have an outwardly projecting flap that mates with valve leaflets (e.g., pericardial leaflets) along the cusps and commissures. A connecting band may be provided that follows the cusps and commissures and extends outwardly. The valve is connected to the natural tissue along the undulating connecting band using conventional techniques, such as sutures. The connecting band may be a cloth-covered silicon member and attaches to the underside of the valve at the cusps to provide support to the stent and to the outer side of the valve at the commissures. The connecting band includes commissure portions defining generally axial gaps that help permit flexing of the valve. | 10-20-2011 |
20110257737 | BIOLOGICALLY IMPLANTABLE PROSTHESIS AND METHODS OF USING THE SAME - A heart valve assembly includes a first annular prosthesis for implantation within a tissue annulus, a second valve prosthesis, and a plurality of magnets on the first and second prostheses to secure the second prosthesis to the first prosthesis. In one embodiment, the magnets are arranged to allow the second prosthesis to be secured to the first prosthesis in a predetermined angular orientation. During use, the first annular prosthesis is implanted into the annulus, and the second valve prosthesis is inserted into the annulus. The magnets orient the second prosthesis relative to the first prosthesis to align the second prosthesis with the first prosthesis in a predetermined angular orientation; and secure the second prosthesis to the first prosthesis in the predetermined angular orientation. | 10-20-2011 |
20110264198 | Transcatheter Prosthetic Heart Valve Delivery System and Method with Controlled Expansion of Prosthetic Heart Valve - A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal end, an intermediate portion, and a first coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve via a first tether. A sheath assembly defines a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The first coupling structure is configured to be manipulated in a first direction to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve. | 10-27-2011 |
20110264199 | Transcatheter Prosthetic Heart Valve Delivery System with Flush Report - A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal portion and an intermediate portion, and an inner lumen extending through the shaft assembly. The delivery system includes a sheath assembly defining an outer lumen sized to slidably receive the shaft assembly. At least one flush port is formed in the intermediate portion. The at least one flush port is in fluid communication with the inner lumen and the outer lumen. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. | 10-27-2011 |
20110264200 | Prosthetic Heart Valve Delivery System with Spacing - A device for percutaneously deploying a stented prosthetic heart valve includes a distal portion, a spacing collar, and an outer collar. The distal portion provides a coupling structure configured to selectively engage the stented prosthetic heart valve. The spacing collar is located proximal to the distal portion. The spacing collar is transitionable from a loaded state to an activated state. The spacing collar in the loaded state has a radial dimension less than the spacing collar in the activated state. The outer collar is configured to be movable relative to the distal portion and the spacing collar. The outer collar is slidably disposed over the spacing collar to provide the loaded state and is slidably retracted from the spacing collar when in the activated state. | 10-27-2011 |
20110264201 | Transcatheter Prosthetic Heart Valve Post-Dilatation Remodeling Devices and Methods - A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks. | 10-27-2011 |
20110264202 | Transcatheter Prosthetic Heart Valve Delivery Device with Biased Release Features - A delivery system for percutaneously delivering and deploying a stented prosthetic heart valve. The delivery device includes a delivery sheath slidably disposed over an inner shaft, and a capture assembly. The capture assembly includes a spindle and a biasing member. The spindle is attached to the inner shaft and defines slot. The biasing member is disposed within the slot and self-transitions from a deflected condition to a normal condition. In a delivery state, the delivery sheath retains the prosthesis over the inner shaft and coupled to the spindle via the capture slot, including a portion of the prosthetic valve being engaged within the slot and the biasing member forced to the deflected condition. In a deployment state, the delivery sheath is proximally withdrawn and the biasing member self-transitions toward the normal condition to eject the prosthetic valve from the capture slot. | 10-27-2011 |
20110264203 | Transcatheter Prosthetic Heart Valve Delivery Device With Passive Trigger Release - A delivery device for percutaneously deploying a prosthetic valve includes a sheath, an inner shaft, and a release assembly. The release assembly is disposed between the sheath and the inner shaft, and includes a retraction member, a release member, and a retention member. The retraction member can self-retract in length from an extended condition to a retracted condition. The release member can self-expand from a compressed condition to an expanded condition. The retention member is distal the release member. In a delivery state, the sheath end is distal the retention member, the release member is in the compressed condition and the retraction member in the extended condition to retain the prosthesis. In a deployment state, the sheath end is positioned to permit the release member to self-transition to the expanded condition, allowing the retraction member to self-transition to the retracted condition and release the prosthesis. | 10-27-2011 |
20110264204 | DEVICES AND METHODS FOR DELIVERING AN ENDOCARDIAL DEVICE - Apical reconstruction and support devices for use in a patient's ventricle include removable implants that may partition the ventricle. Such devices may be implanted using an applicator or system configured for inserting, repositioning and/or removing them. Described herein are applicators, systems, and methods of positioning, deploying and removing cardiac implants. The implants described herein may be inserted into a chamber of a patient's heart, particularly near the apex of the left ventricle, and may support the heart wall. Li some variations the implant is a ventricular partitioning device for partitioning the ventricle into productive and non-productive regions. The applicators may include an expandable member or members at the distal end of a guide to adjustably move the tip of the guide catheter within the ventricle before or during deployment of the implant from the distal end of the guide catheter. These applicators may displace trabeculations within the ventricle. | 10-27-2011 |
20110264205 | EXPANDABLE PROSTHETIC VALVE CRIMPING DEVICE - A device for crimping an implantable device or a part thereof between a radially expanded condition and a radially contracted condition, includes first and second annular bodies arranged about a common axis, and a ring-like array of linear crimping elements having respective opposite ends linked to the first and second annular bodies, respectively. These annular bodies are relatively rotatable around the common axis between a first position, wherein the annular array of crimping elements define a wider orifice for receiving a device to be crimped, and a second position, wherein the annular array of crimping elements define a narrower orifice. | 10-27-2011 |
20110276127 | MULTIPLE INFLATION OF AN EXPANDABLE MEMBER AS A PRECURSOR TO AN IMPLANT PROCEDURE - Devices and methods for assessing the orientation and shape of vessel lumens and hollow portions of organs are described. The devices and methods are particularly adapted for determining the orientation and shape of the native heart valves to facilitate the later implantation of a prosthetic heart valve. The devices are typically catheter-based having an expandable member fixed to a distal end of the catheter. The devices and methods typically comprise deploying the expandable member percutaneously to a target location, expanding the expandable member, performing a valvuloplasty procedure to enlarge the diseased lumen and then performing an assessment of the diseased lumen with the expandable member to determine at least one property of the lumen. An implant device is inserted after assessment of the diseased lumen. | 11-10-2011 |
20110276128 | Prosthetic Heart Valve - Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions. | 11-10-2011 |
20110282438 | Valve Introducers And Methods For Making And Using Them - A valve introducer is provided for delivering a valve prosthesis into a biological annulus. During use, a gasket member is introduced into the biological annulus, and secured relative to the biological annulus. A distal end of a valve introducer is introduced into a passage communicating with the biological annulus, and disposed adjacent the gasket member. A valve prosthesis is advanced through the valve introducer towards the gasket member, and secured to the gasket member. In one embodiment, the valve introducer and valve prosthesis have corresponding shapes, requiring the valve prosthesis to be oriented to properly align the valve prosthesis before advancing the valve prosthesis into the valve introducer. Optionally, the valve introducer is manipulated (e.g., by pivoting at a pivot point) to reduce a profile of the distal end before introduction into the passage, which may facilitate introducing the valve introducer through the passage, e.g., past the sino-tubular junction. | 11-17-2011 |
20110288636 | SUPPORT DEVICE FOR VALVE PROSTHESES AND CORRESPONDING KIT - A support device for implanting stentless valve prostheses, such as biological heart valves, includes a hub and a plurality of support portions for supporting the stentless valve prosthesis. The hub defines a manipulation axis for the device and is flexibly connected to the support portions to allow displacing the manipulation axis for the device between the support portions. | 11-24-2011 |
20110288637 | Percutaneous Mitral Annular Stitch to Decrease Mitral Regurgitation - This invention relates to methods and devices for treatment of regurgitation by connecting the anterior and posterior mitral annulus with a plurality of stitches or anchors called “mitral annulus bands”, instead of anchoring via the coronary sinus. | 11-24-2011 |
20110295366 | MOUNTING TOOL FOR LOADING A PROSTHESIS - The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The disclosure also includes a mounting tool for mounting the prosthesis onto a loading tool, the loading tool useful for loading the prosthesis onto a device for delivering the prosthesis into the patient's heart. Control devices and methods for using these devices are also disclosed. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation. | 12-01-2011 |
20110301700 | PERCUTANEOUSLY DELIVERABLE HEART VALVE AND METHODS ASSOCIATED THEREWITH - A prosthetic heart valve implantable by catheter without surgery includes a substantially “dry” membrane or tissue material. In at least one embodiment, the tissue is folded in a dry state to form a tissue leaflet assembly that is then attached to a frame to form an implantable prosthetic heart valve. Alternatively, one or more tissue leaflets are operatively associated with a frame to form an implantable prosthetic heart valve. The implantable prosthetic heart valve is subsequently pre-mounted on an integrated catheter delivery system. The catheter delivery system that includes the implantable prosthetic heart valve is then packaged and transported while the tissue remains dry. The implantable prosthetic heart valve, while remaining substantially dry, can then be implanted into the receiving patient. | 12-08-2011 |
20110301701 | METHOD AND APPARATUS FOR MINIMALLY INVASIVE HEART VALVE PROCEDURES - An apparatus ( | 12-08-2011 |
20110301702 | Transcatheter Delivery System and Method with Controlled Expansion and Contraction of Prosthetic Heart Valve - A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly. | 12-08-2011 |
20110307055 | METHODS AND DEVICES FOR CAPTURING AND FIXING LEAFLETS IN VALVE REPAIR - The present invention provides methods and devices for grasping, and optional repositioning and fixation of the valve leaflets to treat cardiac valve regurgitation, particularly mitral valve regurgitation. Such grasping will typically be atraumatic providing a number of benefits. For example, atraumatic grasping may allow repositioning of the devices relative to the leaflets and repositioning of the leaflets themselves without damage to the leaflets. However, in some cases it may be necessary or desired to include grasping which pierces or otherwise permanently affects the leaflets. In some of these cases, the grasping step includes fixation. | 12-15-2011 |
20110313516 | PERCUTANEOUS MAGNETIC CATHETER - A percutaneous magnetic catheter may be used to position one or more magnetic components near a magnetically driven prosthesis in a patient's heart in order to adjust the magnetically driven prosthesis. In certain embodiments, the one or more magnetic components are rotatable. Rotation of the one or more magnetic components cause variations in a magnetic field. Variations in the magnetic field may be utilized to adjust the size or shape of a magnetically driven prosthesis. In this way, a magnetically driven prosthesis may be adjusted after a patient has recovered from a surgery in which the magnetically driven prosthesis was implanted. Further, a magnetically driven prosthesis may be adjusted based upon progression of a heart condition. | 12-22-2011 |
20110319988 | Device and System for Transcatheter Mitral Valve Replacement - This invention relates to the design and function of a compressible valve replacement prosthesis which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve. | 12-29-2011 |
20110319989 | TRANSCATHETER MITRAL VALVE PROSTHESIS - A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart. | 12-29-2011 |
20110319990 | DEVICES, SYSTEMS, AND METHODS FOR SUPPLEMENTING, REPAIRING OR REPLACING A NATIVE HEART VALVE LEAFLET - An implant for supplementing, repairing, or replacing a native heart valve leaflet or leaflets provides a scaffold, which defines a pseudo-annulus. The implant further has at least two struts in generally oppositely spaced apart positions on the scaffold. The scaffold can be placed in an elastically loaded condition in a heart with the struts engaging tissue at or near the leaflet commissures of a heart valve annulus, to reshape the annulus for leaflet coaptation. The implant further provides a neoleaflet element coupled to the scaffold within pseudo-annulus, to provide a one-way valve function. | 12-29-2011 |
20120010699 | METHOD AND APPARATUS FOR PROSTHETIC VALVE REMOVAL - A method and apparatus for facilitating transapical removal of a prosthetic heart valve, i.e., percutaneously implantable valve (PIV), with-out open-heart surgery. The apparatus includes a holding tool for holding the PIV, a cutting tool for separating the PrV from fibrotic tissue accumulating around the PIV, and a removal tool for extracting the PIV from the heart. | 01-12-2012 |
20120016468 | LOW CROSSING PROFILE DELIVERY CATHETER FOR CARDIOVASCULAR PROSTHETIC IMPLANT - A delivery catheter and a method for deploying a cardiovascular prosthetic implant using a minimally invasive procedure are disclosed. The delivery catheter comprises an elongate, flexible catheter body having a proximal end and a distal end, wherein the distal end has an outer diameter of | 01-19-2012 |
20120016469 | Methods and Apparatus for Endovascularly Replacing a Heart Valve - The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor. | 01-19-2012 |
20120016470 | TRANSCATHETER HEART VALVE WITH MICRO-ANCHORS - Various embodiments of methods and apparatus for treating defective heart valve are disclosed herein. In one exemplary embodiment, a transcatheter heart valve is disclosed that includes an expandable shape memory stent and a valve member supported by the stent. A plurality of micro-anchors can be disposed along an outer surface of the stent for engaging native tissue. The transcatheter heart valve can be configured to be advanced into a dilated valve annulus via a balloon catheter. The balloon can be inflated to expand the transcatheter heart valve from a collapsed diameter to an over-expanded diameter such that the micro-anchors engage tissue along the surrounding valve annulus. After engaging the tissue, the balloon can be deflated and the shape memory stent can retract or recoil toward its predetermined recoil diameter. As the stent recoils, the surrounding tissue is pulled inward by the stent such that the diameter of the valve annulus is reduced. | 01-19-2012 |
20120016471 | Low Profile Heart Valve and Delivery System - Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve. | 01-19-2012 |
20120022639 | GUIDE WIRES WITH COMMISSURAL ANCHORS TO ADVANCE A PROSTHETIC VALVE - Apparatus is provided, including one or more valve support guide members configured to be delivered to one or more commissures of a native atrioventricular valve of a patient, one or more valve support anchors configured to be anchored to the one or more commissures of the native valve, a prosthetic valve support advanceable toward the native valve along the one or more valve support guide members and anchored to the native valve at least the one or more commissures, and a prosthetic valve configured to be coupled to the valve support. Other applications are also described. | 01-26-2012 |
20120022640 | TECHNIQUES FOR PERCUTANEOUS MITRAL VALVE REPLACEMENT AND SEALING - Apparatus and methods are described, including one or more valve support guide members that are delivered to one or more commissures of a native atrioventricular valve of a patient. A prosthetic valve support is advanced toward the native valve along the one or more valve support guide members and placed at the native valve. A prosthetic valve is coupled to the valve support. One or more sealing elements facilitate sealing of an interface between the prosthetic valve support and the native valve. Other applications are also described. | 01-26-2012 |
20120022641 | Valve Holder - Methods and apparatus for holding and maneuvering a valve during preparation and attachment to patient, providing increased visibility of the prosthetic valve and the sewing ring to prevent suture entanglement. A handle attachment is spaced from the valve for improved visibility of the sewing ring and the outlet end of the valve during attachment. Commissure posts are bent inward at the tips while preventing crashing of the commissure posts into each other causing damage. A release force needed to remove the holder and unthread the holder sutures is reduced. The holder and related methods can provide a kink free holder suture path to reduce suture entanglement and prevent damage to the implanted valve during holder removal by reducing the release force needed to remove the holder sutures by up to 30%. | 01-26-2012 |
20120029627 | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements - The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve. | 02-02-2012 |
20120029628 | METHOD OF RESHAPING A VENTRICLE - Methods for restoring the conical shape of a dilated heart ventricle, or at least reshaping the ventricle to a more conical shape to counter the effects of dilation, thereby improving pumping efficiency. In an exemplary embodiment, a reshaping apparatus comprises an implantable body that can be delivered to a dilated left ventricle via the patient's vasculature in a minimally-invasive procedure. When deployed inside the left ventricle, the body is adapted to apply a longitudinal (downward) force against the inner surface of the left ventricle that causes the ventricle to distend or elongate downwardly relative to the base of the heart so as to at least partially restore the conical shape of the heart. In other embodiments, one or more tension members can be secured to heart tissue inside a heart chamber or on the outside of the heart and placed in tension to reshape the geometry of the heart. | 02-02-2012 |
20120029629 | MITRAL CERCLAGE ANNULOPLASTY APPRATUS - A mitral cerclage annuloplasty apparatus comprises a tissue protective device and a knot delivery device. The tissue protective device comprises a first protective tube and a second protective tube. The knot delivery device comprises a tube wherein a loose knot is looped around its distal end through a hole and wherein tight knot is formed when the distal end of the tube is cut open. Alternatively, the knot delivery device comprises an inner tube and outer tube. The inner tube is insertable and rotatable inside the outer tube. When the tubes are in a closed position by rotating either the outer tube or the inner tube, a hole is created near its distal end. When the tubes are in open position by rotating either the outer tube or the inner tube, the hole joins the opening of the outer tube and lengthens. | 02-02-2012 |
20120035717 | Catheter Assembly with Valve Crimping Accessories - Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. In one embodiment, a catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter. | 02-09-2012 |
20120035718 | DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 02-09-2012 |
20120041547 | Heart Valve Delivery Catheter With Safety Button - Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. Catheter assemblies according to the present invention can include a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A safety button can be included on the handle assembly to allow for precise and consistent positioning of the prosthetic valve in the body. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. | 02-16-2012 |
20120041548 | APPARATUS FOR ATRIOVENTRICULAR VALVE REPAIR - Apparatus for use in repairing an atrioventricular valve in a patient is provided. The apparatus comprises a fastening mechanism for use in repairing a mitral valve in the heart of a patient. The mechanism includes a first end, a second end, and a body extending therebetween. The mechanism is configured to be positioned in the patient's heart using at least one of a guide catheter and an interventional tool that positions the fastening mechanism without penetrating a myocardium. The first end is configured to couple to the valve leaflet while the heart is non-arrested. The second end is configured to couple to a structure other than the valve leaflet, such that the mechanism remains coupled within the heart after being coupled within the heart and simulates the function of a natural chordae. | 02-16-2012 |
20120041549 | REPOSITIONABLE HEART VALVE AND METHOD - A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site. | 02-16-2012 |
20120046739 | METHOD OF DELIVERING A MEDICAL DEVICE ACROSS A PLURALITY OF VALVES - Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided. | 02-23-2012 |
20120046740 | MEDICAL DEVICES AND DELIVERY SYSTEMS FOR DELIVERING MEDICAL DEVICES - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 02-23-2012 |
20120059457 | MINIMALLY INVASIVE SURGICAL INSTRUMENT FOR DELIVERY OF CARDIAC DEVICES - A minimally invasive surgical instrument for delivering an external basal annuloplasty device to a heart includes a hollow shaft with a telescopically center tube extending from an end of the hollow shaft. The center tube includes a heart gripping member. A plurality of delivery prongs are slidably coupled to the hollow shaft, each having a distal portion with an expandable wire member for holding the external basal annuloplasty device. A sleeve is telescopically coupled to the expandable wire member. A wire slide is coupled to a proximal portion of the expandable wire member and a sleeve slide is coupled to a proximal portion of the sleeve. The external basal annuloplasty device is mountable on the plurality of delivery prongs by inserting each expandable wire member into a respective pocket on the external basal annuloplasty device. | 03-08-2012 |
20120065728 | Stentless Support Structure - A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve. | 03-15-2012 |
20120065729 | SYSTEMS AND METHODS FOR RAPIDLY DEPLOYING SURGICAL HEART VALVES - A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps. | 03-15-2012 |
20120071968 | ROBOTIC HEART VALVE ANNULUS SIZER - A heart valve annulus sizer is provided for measuring a valve to be fitted with an annuloplasty ring. The sizer may include a body having a peripheral portion defining an opening, at least one rib disposed within the opening and dividing the opening into at least a first opening and a second opening, and an anchor disposed on and projecting from the body. The sizer may include a length of suture connected to the body. The anchor may include an aperture adapted to receive the length of suture. A method of using the sizer is provided that includes grasping the sizer with an instrument and positioning the sizer adjacent to a valve into a position suitable to allow for measurement of the valve. | 03-22-2012 |
20120078350 | RETAINERS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device for an implantable medical device having at least one retention member at an end thereof includes a shaft extending in a longitudinal direction, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside of the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and at least one acceptance in the retainer adapted to receive the retention member of the medical device in the assembled condition. The sheath is slidable relative to the shaft in the longitudinal direction to uncover and deploy the medical device. The retainer may be rotatable relative to the shaft to reduce torsional forces in the medical device during delivery and deployment. The retainer may have at least one recess facing the compartment for receiving a strut at an end of a stent of the medical device. | 03-29-2012 |
20120078351 | DELIVERY SYSTEM FOR COLLAPSIBLE HEART VALVE - A delivery system for delivering a collapsible prosthetic heart valve includes a valve support structure for supporting a collapsible prosthetic heart valve, and a distal sheath movable in a longitudinal direction relative to the valve support structure between a first position in which the distal sheath is adapted to surround a collapsible prosthetic heart valve supported on the valve support structure, and a second position in which the distal sheath is adapted to expose the collapsible prosthetic heart valve for deployment. The distal sheath is at least partially formed of an inner polymer layer, an outer polymer layer, and a tubular supporting member sandwiched between the inner polymer layer and the outer polymer layer. | 03-29-2012 |
20120078352 | STAGED DEPLOYMENT DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device for a collapsible heart valve includes an operating handle, including a frame defining a movement space therein, a carriage assembly moveable within the movement space, and a first resheathing lock having a locked position and an unlocked position. The delivery device further includes a catheter assembly, including a first shaft around which a valve-receiving compartment is defined, the first shaft being fixedly connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly. The distal sheath is moveable between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve. With the resheathing lock in the locked position, the distal sheath is unable to move to the open condition to fully deploy the valve. | 03-29-2012 |
20120078353 | REPLACEMENT HEART VALVES, DELIVERY DEVICES AND METHODS - A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve. | 03-29-2012 |
20120078354 | APPARATUS FOR REPLACING A CARDIAC VALVE - A prosthetic heart valve in combination with a delivery assembly that includes a first elongate component that is movably disposed to a second elongate component. The delivery assembly has a temporary valve location relative to the delivery assembly to which the prosthetic heart valve can be releasably mounted in position and a spaced implantation location relative to the delivery assembly to which the prosthetic heart valve can also be releasably mounted in position. The prosthetic heart valve and delivery assembly combination is configurable with movement of the first elongate component relative to the second elongate component from a delivery state with the prosthetic heart valve mounted in the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary, location to the implantation location so that the prosthetic heart valve can subsequently be deployed from the implantation location. | 03-29-2012 |
20120078355 | DEPLOYMENT TECHNIQUES FOR ANNULOPLASTY RING AND OVER-WIRE ROTATION TOOL - Apparatus is provided for use with a subject, including an implant comprising a sleeve shaped so as to define a lumen therein, the sleeve having first and second portions. A contracting mechanism is coupled to a portion of an outer surface of the sleeve in a vicinity of the first portion of the sleeve. An elongated contracting member is coupled at a first end portion thereof to the contracting mechanism, and coupled at a second end portion thereof to the sleeve in a vicinity of the second portion of the sleeve. The contracting mechanism comprises a driving interface that is positioned so as to be accessible from the portion of the outer surface of the sleeve. The contracting mechanism is configured such that rotation of the driving interface contracts the implant by tightening the elongated contracting member. Other applications are also described. | 03-29-2012 |
20120083874 | DEVICE FOR COLLAPSING AND LOADING A HEART VALVE INTO A MINIMALLY INVASIVE DELIVERY SYSTEM - A device is provided for collapsing a stented bioprosthetic valve, including first section and second sections, each spanning between first and second ends of the device. The second section of the device is associated with the first section to at least partially enclose an internal cavity formed by the first and second sections, the internal cavity tapering from an open insertion portion at a first end of the device to an open exit portion at a second end of the device. The insertion portion has a larger dimension than the exit portion. When the first section and second section are substantially enclosing the internal cavity, a stented bioprosthetic valve may be inserted into the insertion portion and collapsed as it is moved toward and through the exit portion. The valve may then be loaded on an apparatus for insertion into the body. | 04-05-2012 |
20120083875 | ASSEMBLY AND METHOD FOR LOADING A SELF-EXPANDING COLLAPSIBLE HEART VALVE - An assembly for collapsing a prosthetic heart valve includes a compression member and a pusher member. The compression member has a first open end with a first diameter, a second open end with a second diameter less than the first diameter, and a tapered wall between the first open end and the second open end. The pusher member has a base adapted to engage an end of the valve. The pusher member and the compression member are movable relative to one another between an initial position in which the base of the pusher member is relatively far from the first open end of the compression member and an operative position in which the base of the pusher member is relatively close to the first open end of the compression member. Movement of the pusher and compression members from the initial position to the operative position radially compresses the valve. | 04-05-2012 |
20120083876 | PREPARATION METHODS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device for a collapsible prosthetic heart valve includes a support shaft around which a compartment is defined, an inner shaft extending through the support shaft and adapted to slide relative to the support shaft along a longitudinal axis thereof, the inner shaft having a lumen therethrough, and a distal sheath operatively connected at a distal end to the inner shaft and slidable therewith. The compartment may receive the valve in an assembled condition, and may be selectively covered and uncovered by the distal sheath. A first flow path may provide flow communication between the lumen of the inner shaft and the compartment. | 04-05-2012 |
20120083877 | EXPANDABLE SHEATH FOR INTRODUCING AN ENDOVASCULAR DELIVERY DEVICE INTO A BODY - Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some embodiments include an elastic outer cover positioned outside the outer layer. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths. | 04-05-2012 |
20120095549 | Prosethetic Haert Valves, Scaffolding Structures, and Systems and Methods for Implantation of Same - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. | 04-19-2012 |
20120109288 | Reconfiguring Heart Features - Among other things, a heart tissue support has gripping elements, each element having a free end that is sharp enough to penetrate heart tissue when pushed against the tissue, and a feature to resist withdrawal from the tissue after the sharp free end has penetrated the tissue. Among other things, the shape of a heart valve annulus is corrected in a catheter laboratory by orienting a tip of a catheter holding a heart tissue support that has gripping elements at the valve annulus, applying a radial force from the catheter against the annulus by opening a structure at the tip of the catheter, and while the structure is opened, forcing the support onto the annulus. Among other things, the shape of a heart valve annulus is corrected during a surgical procedure by pushing a heart tissue support that has gripping elements onto the annulus. | 05-03-2012 |
20120109289 | Reconfiguring Heart Features - Among other things, a heart tissue support has gripping elements, each element having a free end that is sharp enough to penetrate heart tissue when pushed against the tissue, and a feature to resist withdrawal from the tissue after the sharp free end has penetrated the tissue. Among other things, the shape of a heart valve annulus is corrected in a catheter laboratory by orienting a tip of a catheter holding a heart tissue support that has gripping elements at the valve annulus, applying a radial force from the catheter against the annulus by opening a structure at the tip of the catheter, and while the structure is opened, forcing the support onto the annulus. Among other things, the shape of a heart valve annulus is corrected during a surgical procedure by pushing a heart tissue support that has gripping elements onto the annulus. | 05-03-2012 |
20120123528 | STAGED DEPLOYMENT DEVICES AND METHOD FOR TRANSCATHETER HEART VALVE DELIVERY - A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve. | 05-17-2012 |
20120123529 | PROSTHETIC HEART VALVE - Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft. | 05-17-2012 |
20120136433 | INTRAOPERATIVE AND POST-OPERATIVE ADJUSTMENT OF AN ANNULOPLASTY RING - An intraoperative adjustment device is described. In some embodiments, the device includes an elongate body including a proximal end and a distal end, the distal end configured to penetrate an outer surface of an adjustable cardiac implant implanted in a patient's heart, and the proximal end and the distal end connected by at least one energy-transfer member. In some embodiments, the distal end includes at least one electrode coupled to the energy-transfer member and configured to deliver an activation energy to the adjustable cardiac implant. In some embodiments, the proximal end is configured to attach to an energy source that provides the activation energy. In some embodiments, the proximal end is configured to be located outside the patient's body while the distal end is coupled to the adjustable cardiac implant that is implanted in the patient's heart. | 05-31-2012 |
20120136434 | ERGONOMIC MITRAL HEART VALVE HOLDERS - A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation. The holder may be shaped as a ring with an open inner diameter for enhanced access to the commissure posts and leaflets. | 05-31-2012 |
20120143319 | In-Situ Formation of a Valve - The present invention satisfies the long felt need for a more compact and durable valve which may be formed in situ. The present invention provides a self-deployable valve system, a method of delivery, and a method of manufacturing for the self-deployable valve system. The present invention delivers the necessary components for forming a complete valve system in situ. The collapsed subcomponents of the system lack any functional characteristics commonly associated with a valve before being expanded. However, once expanded, the system is transformed into a competent valve for use in a wide variety of applications. | 06-07-2012 |
20120150287 | Prosthetic Valve Implantation Systems - Prosthetic valves implantation methods and systems, especially as related to fitting a prosthetic valve at the site of a native stenotic or incompetent valve are described. The subject devices, systems and associated dock deployment and implant docking techniques may be employed in percutaneous valve replacement procedures. | 06-14-2012 |
20120150288 | PROSTHETIC HEART VALVE PACKAGING AND DEPLOYMENT METHODS - Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly. | 06-14-2012 |
20120150289 | Methods and Devices for Delivery of Prosthetic Heart Valves and Other Prosthesis - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described. | 06-14-2012 |
20120158128 | PROSTHETIC HEART VALVE DELIVERY SYSTEMS AND PACKAGING - Packaging for dry prosthetic tissue heart valves and their delivery systems includes a primary sterile barrier that permits gas sterilization of the tissue implant, and a secondary sterile barrier that also prevents oxidation of the implant during long-term storage. Dry tissue heart valves and their delivery systems are placed within a primary container such as a rigid tray that limits movement of the components therein. The primary container is placed within a secondary container, and the assembly is then sterilized. The outer sterile barrier may include a double seal so that a first gas-permeable seal can be closed for sterilization, after which a second gas-impermeable seal can be closed to seal out any further oxygen contact with the tissue implant. A collapsible delivery handle for a surgical heart valve may be provided which reduces the size of the packaging. | 06-21-2012 |
20120158129 | SYSTEMS AND METHODS FOR POSITIONING A HEART VALVE USING VISUAL MARKERS - A valve retainer is connected to an elongate delivery member. The valve retainer is configured to releasably secure a prosthesis (e.g., a heart valve prosthesis) to the delivery member during delivery to a target site in a body (e.g., a native valve annulus). The valve retainer includes a rotational identifier that identifies the rotational orientation of the valve retainer when the valve retainer is positioned proximate to the target site. A heart valve prosthesis can include a commissural post that has a predetermined rotational position relative to the rotational identifier, such that the heart valve prosthesis can be rotationally aligned with the native commissures of the native valve by rotating the delivery member and the valve retainer until the commissural post is aligned with a native valve commissure and the rotational identifier is visible. | 06-21-2012 |
20120165924 | Method and Device for Treatment of Mitral Insufficiency - A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced. | 06-28-2012 |
20120165925 | FIXING DEVICE, IN PARTICULAR FOR FIXING TO VASCULAR WALL TISSUE - An arrangement includes a first sleeve; a fixing device for fixing to vascular wall tissue; and a second sleeve. The fixing device includes a tubular element for accommodation within a passage surrounded by vascular wall tissue and is provided with fingers arranged distributed in the peripheral direction of the tubular element. The fingers have a first position in which they project radially outwards from the tubular element. The fingers are bent aside reversibly, against a resilient force, from the first position into a second position in which the projection of the fingers on a radial transverse surface of the tubular element is located essentially on and/or within the periphery of the tubular element. The fingers are fixed in the second position by the first sleeve in which the tubular element and fingers, which are in the second position, are accommodated to form a composite assembly. | 06-28-2012 |
20120165926 | Methods and Devices for Delivery of Prosthetic Heart Valves and Other Prosthetics - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described. | 06-28-2012 |
20120165927 | Valve with Delayed Leaflet Deployment - A valve for use in a body lumen, where the valve includes a valve leaflet with delayed leaflet deployment relative an in vivo implant time. The valve includes a valve frame, a valve leaflet coupled to the valve frame. The valve leaflet includes a commissure that can reversibly seal for unidirectional flow of a liquid through the valve, and a biodegradable adhesive between the valve leaflet and the valve frame to hold at least the commissure of the valve leaflet in a static relationship relative the valve frame for a predetermined time once implanted in vivo. | 06-28-2012 |
20120179243 | METHODS AND APPARATUSES FOR DEPLOYING MINIMALLY-INVASIVE HEART VALVES - A method for replacing native valve function of a diseased aortic valve in a patient is provided. The method comprises: (a) guiding a catheter system having a balloon through the vasculature of the patient; (b) guiding an artificial heart valve assembly through the vasculature of the patient; (c) while the catheter system is in the patient's vasculature, positioning the artificial heart valve assembly about the balloon of the catheter system; (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve; (e) while the patient's heart is beating, expanding the artificial heart valve assembly in the region of the diseased aortic valve; and (f) withdrawing the catheter system from the patient's vasculature. | 07-12-2012 |
20120179244 | Device and System for Transcatheter Mitral Valve Replacement - This invention relates to the design and function of a compressible valve replacement prosthesis which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve. | 07-12-2012 |
20120179245 | METHODS OF ASSEMBLING AND DELIVERING AN ANNULOPLASTY RING - A holder for an annuloplasty ring having a template defining a proximal face opposite the distal face, and a peripheral edge about which the annuloplasty ring conforms. The annuloplasty ring anchors to the template using one or more flexible filaments. The template includes a single cutting well on its proximal face over which the flexible filament is suspended. Desirably, the single cutting well is located adjacent the peripheral edge so as to be away from any handle connections for ease of access. The flexible filament emerges above the proximal face of the template at only one location at the cutting well, thus presenting a one cut quick-release structure that is highly visible to the surgeon. | 07-12-2012 |
20120191181 | SYSTEMS AND METHODS FOR LOCALIZATION OF A PUNCTURE SITE RELATIVE TO A MAMMALIAN TISSUE OF INTEREST - Systems and methods for localization of a puncture site on an atrial wall relative to a mammalian tissue of interest. In at least one embodiment, such a system includes a bodily access system, having an engagement catheter with an open distal end, a first lumen therethrough, and configured to reversibly attach to a first tissue using suction, a puncture device, configured to fit at least partially within the first lumen, and a scanner configured to identify at least a portion of the bodily access system when positioned within the luminal organ and further configured to identify a distance between a second tissue and a portion of the bodily access system. When such a system is used in connection with a therapeutic procedure, the distance between the second tissue and the portion of the bodily access system is used to facilitate a puncture of the first tissue at a desired location. | 07-26-2012 |
20120191182 | PROSTHETIC INSERT FOR TREATING A MITRAL VALVE - A prosthetic insert member for improving the function of a mitral valve is disclosed. The insert member is configured for insertion between leaflets of mitral valve. The insert member has an elongated cross-sectional profile for conforming to the opening in the mitral valve. The device also includes an anchoring member for attachment to heart tissue for maintaining the insert member in the mitral valve. In operation, the insert member fills the opening between the leaflets of the mitral valve and reduces regurgitation while preferably allowing the leaflets to function in a substantially normal manner. In one embodiment, the insert member is formed with a valve member disposed in a passageway for allowing blood to pass through the insert member in one direction. | 07-26-2012 |
20120197388 | COAPTATION ENHANCEMENT IMPLANT, SYSTEM, AND METHOD - Implants, implant systems, and methods for treatment of mitral valve regurgitation and other valve diseases generally include a coaptation assist body which remains within the blood flow path as the leaflets of the valve move, the valve bodies often being relatively thin, elongate (along the blood flow path), and/or conformable structures which extend laterally from commissure to commissure, allowing the native leaflets to engage and seal against the large, opposed surfaces on either side of the valve body during the heart cycle phase when the ventricle contracts to empty that chamber of blood, and allows blood to pass around the valve body so that blood flows from the atrium to the ventricle during the filling phase of the heart cycle. Separate deployment of independent anchors near each of the commissures may facilitate positioning and support of an exemplary triangular valve body, with a third anchor being deployed in the ventricle. An outer surface of the valve body may accommodate tissue ingrowth or endothelialization, while a fluid-absorbing matrix can swell after introduction into the heart. The valve body shape may be selected after an anchor has been deployed, and catheter-based deployment systems may have a desirable low profile. | 08-02-2012 |
20120197389 | Device and Method for Modifying the Shape of a Body Organ - An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel. | 08-02-2012 |
20120203330 | METHOD OF POST-OPERATIVE ADJUSTMENT FOR MITRAL VALVE IMPLANT - The present invention is directed to a mechanism and procedure for adjusting a cardiac implant during the early post-operative period, such as, for example, the first 2-5 days after surgery. During the implant procedure, an adjustment tool is releasably attached to the adjustable implant. The adjustment tool remains connected to the implant following the procedure and extends from the patient's body to allow for post-operative adjustment under normal beating heart conditions. Once the implant is adjusted, the adjustment tool is configured to release from the implant and be removed from the patient's body without requiring access to the patient's heart. | 08-09-2012 |
20120203331 | IMPLANTATION DEVICE - The invention relates to an implantation device ( | 08-09-2012 |
20120203332 | APPARATUS AND METHOD FOR DELIVERING AN IMPLANTABLE MEDICAL DEVICE TO A DISEASED CARDIAC VALVE - An apparatus is provided for delivering an implantable medical device to a diseased cardiac valve includes an elongated shank, a brace member, and a locking mechanism. The shank has a first end portion, a second end portion, and a first longitudinal axis extending between the end portions. The first end portion includes a rotatable annular lower support and a fixing member. The lower support includes an annular ring having oppositely disposed upper and lower surfaces and a plane extending radially between the upper and lower surfaces. The brace member includes a barrel portion operably connected to a drive system. The barrel portion includes a first end portion, a second end portion, and a second longitudinal axis extending between the end portions. The drive system includes a housing operably connected to an actuating handle. The locking mechanism is operably connected to the housing and the elongated shank. | 08-09-2012 |
20120203333 | PERCUTANEOUS AORTIC VALVE - A method of minimally invasively replacing a cardiac valve of a patient including inserting a delivery catheter intraluminally, inserting a valve resecting instrument intraluminally through the delivery catheter to a position adjacent the cardiac valve of a patient, manipulating the valve resecting instrument to resect the cardiac valve, removing the resected valve through the delivery catheter, and providing a delivery instrument having a replacement valve contained therein. The delivery instrument is advanced into the delivery catheter and intraluminally so that a distal end portion of the instrument is adjacent an annulus of a patient, and a first portion of the valve is exposed from the delivery instrument to position it on a first side of the annulus, and thereafter a second portion of the valve is exposed to position it on a second side of the annulus. | 08-09-2012 |
20120203334 | Leaflet Valve - A device and method for improving flow through a native blood vessel valve, such as the aortic valve, are provided. The present invention allows a miniature valve to be implanted into affected leaflets percutaneously, obviating the need for coronary bypass surgery. The method includes the cutting of small holes, on the order of 4 mm, in the leaflets of a targeted valve, thereby allowing blood to flow through the newly formed holes. The holes are used as attachment sites for the miniature valves of the present invention. | 08-09-2012 |
20120209374 | METHODS OF TREATING VALVES - The implant implantation unit ( | 08-16-2012 |
20120209375 | STABILITY DEVICE FOR USE WITH PERCUTANEOUS DELIVERY SYSTEMS - A delivery system for stabilizing a catheter shaft across an aortic arch can include one or more stabilizing members configured to fix or stabilize the position of the catheter relative to the aortic arch of a patient. | 08-16-2012 |
20120209376 | DEVICE AND METHOD FOR RESHAPING MITRAL VALVE ANNULUS - Methods for treating a defective mitral valve are provided. One preferred method comprises attaching opposing ends of a tether to opposing regions of the mitral valve annulus. The tether is advanced percutaneously into the left atrium by a therapy catheter. Vacuum ports may be provided on the therapy catheter for grasping tissue along the mitral valve annulus. The therapy catheter may also include advanceable needles for passing the tether through the tissue. Alternatively, the ends of the tether may be attached to fastener elements which are secured to the tissue. Tension in the tether pulls the opposing regions of the mitral valve annulus into closer proximity for improving mitral valve function. | 08-16-2012 |
20120209377 | DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS, INCLUDING THE USE OF MAGNETIC TOOLS - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 08-16-2012 |
20120215302 | Annuloplasty Ring Holder - An annuloplasty ring holder including a head having an upper surface and an annuloplasty ring receiving surface facing opposite the upper surface. The annuloplasty ring holder also includes means for attaching an annuloplasty ring to the annuloplasty ring receiving surface. The means for attaching an annuloplasty ring to the annuloplasty ring receiving surface may include one or more suture guides operatively associated with the head and configured to position one or more sutures to removably associate an annuloplasty ring with the annuloplasty ring receiving surface. The head may include a central hub and more than one spoke radiating out from the central hub. If the head is thus configured, each spoke will include a portion of the annuloplasty ring receiving surface. | 08-23-2012 |
20120232645 | DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS, INCLUDING THE USE OF MAGNETIC TOOLS - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 09-13-2012 |
20120239142 | PROSTHETIC HEART VALVE DELIVERY APPARATUS - Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body. | 09-20-2012 |
20120271411 | DEVICES, SYSTEMS AND METHODS FOR ACCURATE POSITIONING OF A PROSTHETIC VALVE - The invention is a system and method for accurately positioning a prosthetic valve such as a prosthetic heart valve at a desired position for deployment. The invention includes extendable positioning elements which provide tactile feedback to a user to confirm proper positioning of the catheter with respect to the native valve annulus. During delivery, the extendable positioning elements lie against the catheter, over the prosthetic valve and expandable balloon, providing a low profile for advancing the catheter to the desired treatment location via small passages such as body lumens. Prior to valve deployment, the positioning elements are extended and brought into contact with tissue of the native annulus to confirm the proper positioning of the delivery system and prosthetic valve. | 10-25-2012 |
20120277853 | System and Method for Percutaneous Mitral Valve Repair - A system for minimally invasive repair of a mitral valve including a catheter, a capture body and a surgical fastener. The capture body includes legs extending from a center portion, and is self-transitionable from a collapsed arrangement to a normal arrangement in which the legs extend in a common wind direction. The fastener has a self-closing clip forming a loop in an undeflected arrangement. In a delivery state, the capture body and fastener are disposed within the catheter and forced to the collapsed and deflected arrangements, respectively. In a capture state, the capture body legs are distal the catheter and self-assume the normal arrangement for capturing chordae. In a release state, the fastener is released from the catheter and the clip self-transitions toward the undeflected arrangement for securing the mitral valve leaflets. | 11-01-2012 |
20120277854 | Delivery Systems and Methods of Implantation for Replacement Prosthetic Heart Valves - A method of delivering a replacement prosthetic valve to a previously implanted prosthetic valve including the steps of compressing a replacement prosthetic valve having an expandable stent within a sheath of a delivery system, wherein the delivery system comprises a proximal end, a distal end, and a centering structure positioned between the proximal and distal ends, advancing the delivery system and compressed replacement prosthetic valve into a vessel of a patient until the distal end of the delivery system is positioned adjacent to a second side of a previously implanted prosthetic valve, deploying the centering structure to radially reposition the distal end of the delivery system, further advancing the delivery system toward the previously implanted prosthetic valve, and deploying the replacement prosthetic valve | 11-01-2012 |
20120283823 | METHODS OF IMPLANTING AN IMPLANTATION DEVICE - The implant implantation unit ( | 11-08-2012 |
20120290078 | HEART VALVE DELIVERY SYSTEM WITH VALVE CATHETER - A heart valve delivery system is provided wherein a prosthetic valve is carried on a valve catheter inside a tubular delivery sleeve. The valve catheter has a distal end coupled to a mop. The mop comprises a plurality of flexible extensions configured for releasable attachment to the prosthetic valve. A lead screw nut is coupled to a proximal end of the tubular delivery sleeve and a lead screw is coupled to the valve catheter. The lead screw engages the lead screw nut and rotation of the lead screw causes the delivery sleeve to retract relative to the valve catheter and the prosthetic valve for exposing the prosthetic valve. The flexible extensions of the mop allow expansion of the valve while maintaining the attachment during placement of the valve at a native valve site. | 11-15-2012 |
20120296417 | Corkscrew Annuloplasty Device - An annuloplasty device having a plurality of corkscrew anchors is herein disclosed. In some embodiments, the annuloplasty device includes a core wire extending along the length of the device, and at least one corkscrew wire which is operably connected to the corkscrews to screw the corkscrews into heart tissue. In certain embodiments, one or more of the corkscrew wires includes a drive key and the corkscrew anchors are connected to a sleeve with a keyway that engages the drive key on the corkscrew wires. In addition, in some embodiments, the device includes a retractable sheath, which is disposed over the corkscrews to protect them during insertion of the device. | 11-22-2012 |
20120303116 | VALVE PROSTHESIS - The present disclosure relates to valve replacement devices that are foldable for catheter-based deployment to the site of implantation, as well as systems for the delivery of valve prostheses, including prostheses having the special characteristics of the disclosed valve replacement devices. The devices include highly effective adhering mechanisms for secure and enduring precision implantation. The adhering mechanisms may employ a unique sealing mechanism that includes a cuff that expands slowly whereby the device is not secured in place until the completion of the implantation procedure. The implanted device, optionally together with the cuff, prevents perivalvular leaks and incorporate an appropriate leaflet system for reliable functioning in situ. | 11-29-2012 |
20120310330 | PERCUTANEOUS TRANSCATHETER REPAIR OF HEART VALVES VIA TRANS-APICAL ACCESS - Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves via a trans-apical approach to accessing the heart. A guiding sheath may be introduced into a ventricle of the heart through an access site at an apex of the heart. A distal end of the guiding sheath can be positioned retrograde through the target valve. An annuloplasty ring arranged in a compressed delivery geometry is advanced through the guiding sheath and into a distal portion of the guiding sheath positioned within the atrium of the heart. The distal end of the guiding sheath is retracted, thereby exposing the annuloplasty ring. The annuloplasty ring may be expanded from the delivery geometry to an operable geometry. Anchors on the annuloplasty ring may be deployed to press into and engage tissue of the annulus of the target valve. | 12-06-2012 |
20120310331 | METHODS AND APPARATUS FOR ATRIOVENTRICULAR VALVE REPAIR - Methods and devices are disclosed for minimally invasive procedures in the heart. In one application, a catheter is advanced from the left atrium through the mitral valve and along the left ventricular outflow tract to orient and stabilize the catheter and enable a procedure such as a “bow tie” repair of the mitral valve. Right heart procedures are also disclosed. | 12-06-2012 |
20120310332 | Delivery Catheter System With Micro and Macro Movement Control - A prosthetic valve delivery system that is improved in controllability by way of a proximal handle system. Such a handle system of the present invention advantageously permits a controlled fine or micro movement or adjustment of a distal sheath for uncovering a plunger that is to be loaded with a prosthetic valve for deployment thereof. The delivery system of the present invention permits a trigger-release for a gross or macro movement to the sheath relative to the plunger. Also, the control handle of the delivery system is shaped and contoured for ease in manipulation of the micro-control actuator. | 12-06-2012 |
20120310333 | SINGLE CATHETER MITRAL VALVE REPAIR DEVICE AND METHOD FOR USE - A single catheter valve repair device for stabilizing a tissue portion and selectively applying a tissue fastener thereto. The single catheter valve repair device of the present invention includes an extendable engagement tip having at least one vacuum port formed thereon, at least one deployable fastener in communication with the engagement tip, and at least one actuator member in communication with the port. The deployable fastener is capable of controllably engaging and fastening a tissue segment located proximal to the engagement tip. | 12-06-2012 |
20120310334 | Prosthetic Valve Delivery System - A prosthetic valve delivery system for percutaneously delivering and deploying a prosthetic valve within an existing valve is disclosed. The delivery system includes a stented prosthetic valve having a balloon-expandable stent portion with a prosthetic valve disposed therein and at least one self-expanding stent portion. The delivery system further includes a dual balloon catheter having a first balloon on which the stented prosthetic valve is disposed during delivery and a second balloon. Upon delivery within the existing valve, the self-expanding stent portion contacts the existing valve and the first balloon expands the balloon-expandable stent portion to a first diameter such that the stented prosthetic valve is in a first stage deployment configuration. The second balloon then expands the balloon-expandable stent portion to a second diameter, greater than the first diameter, such that the stented prosthetic valve is in a second stage deployment configuration being fully deployed within the existing valve. | 12-06-2012 |
20120316640 | Device And Method For Improving Function Of Heart Valve - A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve. | 12-13-2012 |
20120316641 | Device and Method for Reducing Cardiac Valve Regurgitation - A catheter ( | 12-13-2012 |
20120323313 | PROSTHETIC LEAFLET ASSEMBLY FOR REPAIRING A DEFECTIVE CARDIAC VALVE AND METHODS OF USING THE SAME - Methods and apparatus are provided for repairing or replacing a defective cardiac valve including a prosthetic leaflet assembly having an expandable frame with one or more anchors configured to engage a predetermined region of the defective cardiac valve in an expanded deployed state, and at least one prosthetic leaflet coupled to the expandable frame. The prosthetic leaflet assembly is configured such that the prosthetic leaflet is suspended within a flow path of the defective cardiac valve and coapts with, and improves functioning of, one or more native leaflets of the defective cardiac valve. | 12-20-2012 |
20120323314 | EPICARDIAL CLIP - An epicardial clip for reshaping the annulus of the mitral valve of a heart includes a curved member having an anterior segment configured to be positioned in the transverse sinus of the heart, a posterior segment configured to be positioned on the posterior side of the heart, such as on or inferior to the atrioventricular groove, and a lateral segment extending between the anterior segment and the posterior segment. The lateral segment includes a curve such that the first end of the member is positioned at or above the plane of the mitral valve and the second end of the member is positioned at or below the plane of the mitral valve. | 12-20-2012 |
20120330407 | APPARATUS AND METHOD FOR HEART VALVE REPAIR - A transcatheter method of gathering tissue of a heart valve leaflet may include inserting an elongated catheter assembly to a position adjacent the heart valve leaflet, the catheter assembly including a capture tool moveable between a retracted position and an extended position, a tissue support, and a clamping member moveable between an open position and a closed position. The capture tool may be partially retracted to gather tissue of the heart valve leaflet between the tissue support and the clamping member. The clamping member may then be moved from the open position toward the closed position so as to clamp a substantial portion of the gathered tissue of the heart valve leaflet between the tissue support and the clamping member. Subsequently, a clip may be applied from the catheter assembly to the clamped tissue so as to hold the clamped tissue substantially in a gathered configuration. | 12-27-2012 |
20120330408 | SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE - An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device. | 12-27-2012 |
20130013056 | Valve Repair Instrument - A valve repair instrument and method of repair for the mitral valve of the heart is disclosed. The valve repair instrument includes an elongated body having two ends. One of the ends being configured to maintain a muscle portion of a valve repair device in an expanded position for attachment to the papillary muscle, the other end being configured to maintain a leaflet portion of a valve repair device in an expanded position for attachment to a valve leaflet. The valve repair device is attached to the diseased valve by suturing the leaflet portion to the affected leaflet and suturing the muscle portion to the affected muscle. | 01-10-2013 |
20130013057 | MEDICAL IMPLANT DEPLOYMENT TOOL - A medical implant deployment tool and deployment method are disclosed. One aspect of the invention provides an implant system including an implant adapted for endovascular delivery and deployment; and a deployment tool adapted to deploy the implant, with the deployment tool having an actuation controller; a plurality of actuation elements adapted to apply forces to one or more implant deployment mechanisms and each adapted to extend along an actuation element path within a patient's vasculature; and an actuation element compensation mechanism adapted to compensate for differences in length between the actuation element paths. | 01-10-2013 |
20130023983 | METHOD FOR TREATING AN AORTIC VALVE - Expandable, percutaneously deployable, prosthetic heart valves and systems for minimally invasive replacement of damaged or diseased native aortic valves comprise an expandable, tubular stent body and a unidirectional valve assembly. Embodiments of the stent body comprise an annulus anchoring section, a sinus section, and an outflow section, with the outflow section flared outwardly from the sinus section in an expanded configuration. Embodiments of the stent body are self-expanding, comprising, for example nitinol. The valve assembly disposed within the sinus section of the stent body and sutured thereto. Embodiments of the valve assembly comprise three leaflets, each leaflet comprising a curved outer edge sutured to the sinus section of the stent body, and a coapting free edge. Embodiments of the valve leaflets comprise pericardium, for example, porcine pericardium. Embodiments of the prosthetic heart valve have a contracted configuration dimensioned for percutaneous delivery thereof. | 01-24-2013 |
20130030519 | DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE - Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others. | 01-31-2013 |
20130030520 | DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE - Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others. | 01-31-2013 |
20130041459 | Implant Delivery and Deployment System and Method - An implant delivery system comprising a catheter including at least one lumen, an implant configured for receipt in the lumen, and a latching mechanism configured for receipt in the implant. The latching mechanism may be configured to releasably couple the implant to a delivery wire and to transmit torque through the delivery wire to cause at least a portion of the implant to rotate. The an implant may comprise a shaft, a spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position, a garage configured to couple the spacer to a first end region of the shaft, and at least one anchor mechanism. The garage may define a cavity to receive the latching mechanism and to increase rotational and translational stability of the latching mechanism. | 02-14-2013 |
20130046376 | METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES - A method of reducing the risk of clinical sequelae to catheter induced vascular injuries may include introducing a guide wire into a vascular sheath residing in a blood vessel, proximally retracting the vascular sheath while leaving the wire in place, and observing indicia of the presence or absence of a vascular injury caused to the blood vessel by the vascular sheath or a procedural catheter previously advanced through the vascular sheath. If indicia of a vascular injury are observed, the method may further involve proximally retracting the guide wire to position the inflatable balloon adjacent the injury and inflating the balloon to reduce blood flow past the injury, while leaving the guide wire in place to provide subsequent access to the injury. | 02-21-2013 |
20130046377 | Apparatus for Replacing a Cardiac Valve - A delivery assembly for delivering a prosthetic heart valve can include a first elongate component and a second elongate component. The delivery assembly includes a temporary valve location to which the prosthetic heart valve can be releasably mounted and an implantation location to which the prosthetic heart valve can also be releasably mounted. The delivery assembly can move from a delivery state with the prosthetic heart valve mounted to the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary location to the implantation location. The prosthetic heart valve can subsequently be deployed from the implantation location. The position of the prosthetic heart valve relative to the first elongate component at the temporary location is different than a position of the prosthetic heart valve relative to the first elongate component at the implantation location. | 02-21-2013 |
20130060328 | Transcatheter Balloon-Assisted Mitral Valve Navigation Device and Method - A method for positioning a centering introducer in a heart of a patient, which includes the steps of inserting an anchoring wire delivery catheter through a heart wall and to a treatment region of the heart, deploying at least one anchoring wire from the delivery catheter and into tissue in the treatment region of the heart, and removing the delivery catheter from the heart. A centering introducer can then be advanced along the anchoring wire to the treatment region, wherein the centering introducer includes an introducer element and at least one balloon. At least one of the balloons can then be inflated to reorient the introducer element in at least one direction relative to a longitudinal axis of the centering introducer. | 03-07-2013 |
20130073031 | SYSTEMS AND METHODS FOR HOLDING ANNULOPLASTY RINGS - Holders for releasably holding annuloplasty rings prior to and during the implantation of the rings employ any of a variety of features relating to such things as holder shape, handle attachment structures, securement of a ring to the holder, and release of the ring from the holder. In one aspect, the holder includes a flexible bracket and a more rigid connector. In another aspect, the holder includes a flexible bracket and cutting blocks, wherein the interior surface of the cutting block is made of a higher durometer material than the bracket. The interior surface of the cutting block can be coated with a higher durometer material than the material of the bracket. In another aspect, the holder includes a flexible bracket and cutting blocks made of a higher durometer material than the flexible bracket. | 03-21-2013 |
20130073032 | EXPANDABLE RADIOPAQUE MARKER FOR TRANSCATHETER AORTIC VALVE IMPLANTATION - A delivery device for a collapsible prosthetic heart valve includes a support shaft around which a compartment for the valve is defined, a distal sheath adapted to selectively cover and uncover the compartment and the valve, and a marker cage having a collapsed condition when the distal sheath covers the compartment and an expanded condition when the compartment is uncovered. The marker cage includes at least one rib having a radiopaque marker for determining the positioning of the valve as it is deployed. The valve may be assembled around the marker cage so that the marker cage does not interfere with the radial expansion of the valve during deployment. | 03-21-2013 |
20130073033 | EXPANDABLE ANNULOPLASTY RING AND ASSOCIATED RING HOLDER - Devices and methods are provided for surgical repair of dilated aortic root to restore aortic valve competence while preserving native leaflets. In one aspect of the invention an expandable annuloplasty ring is provided for external placement at the base of a dilated aortic root. The expandable ring is capable of elastically expanding between a first diastolic diameter and a larger second systolic diameter to provide a physiologically representative surgical repair of the aortic root. In a further aspect of the invention, is provided a holder assembly for aortic annuloplasty ring and suitable for other cardiac valve prosthesis. The holder assembly consists of a holder body pivotingly coupled to a handle member through a ball-and-socket arrangement. | 03-21-2013 |
20130073034 | Leaflet Reinforcement For Regurgitant Valves - A support, and a method for attaching said support, for providing additional strength to existing regurgitant or prolapsed valve leaflets. The support restores an otherwise non-functioning, or poorly functioning, native valve to a functioning condition, obviating the need for a complete valve removal or replacement. The support may also be applied to a functioning valve leaflet as a prophylactic measure against future failure. The delivery method includes a delivery mechanism for attaching the support to the native valve leaflet. | 03-21-2013 |
20130073035 | Valve Suturing and Implantation Procedures - A prosthesis for implantation at a native semilunar valve includes a prosthetic distal valve, which includes a pliant material configured to collapse inwardly towards a longitudinal axis of the prosthesis during diastole, and to open outwardly during systole, and a distal fixation member configured to be positioned in a downstream artery of the subject. The apparatus also includes a proximal fixation member coupled to the distal fixation member, and configured to be positioned at least partially on a ventricular side of the native semilunar valve. The proximal fixation member is shaped so as to define a lattice that is shaped so as to define an intermediary portion that is coupled to the pliant material of the valve and diverges outwardly from the longitudinal axis, and a distal portion that is distal to the intermediary portion and diverges outwardly from the intermediary portion of the lattice. Other embodiments are also described. | 03-21-2013 |
20130079872 | Distal Tip Assembly for a Heart Valve Delivery Catheter - A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal by of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter. | 03-28-2013 |
20130090724 | TRANSVALVULAR INTRAANULAR BAND AND CHORDAE CUTTING FOR ISCHEMIC AND DILATED CARDIOMYOPATHY - Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets, to inhibit prolapse into the left atrium. At least one marginal chordae is severed, to permit leaflet closure against the band. | 04-11-2013 |
20130090725 | UNITARY QUICK-CONNECT PROSTHETIC HEART VALVE DEPLOYMENT METHODS - A quick-connect heart valve prosthesis that can be quickly and easily implanted is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps. | 04-11-2013 |
20130090726 | RETAINING MECHANISMS FOR PROSTHETIC VALVES - A method of treating a deficient mitral valve without open heart surgery is disclosed. A support band is advanced from a delivery catheter and positioned around native leaflets of the deficient mitral valve. The support band is preferably formed of a shape memory material and is configured to assume a curved shape upon advancement from the delivery catheter. While the support band is positioned around the native leaflets of the mitral valve, an expandable prosthetic heart valve is delivered through an apex of the left ventricle and into the mitral valve. The expandable prosthetic heart valve is then expanded within the mitral valve, thereby causing one or more of the native leaflets of the mitral valve to be frictionally secured between the support band and the prosthetic heart valve. | 04-11-2013 |
20130090727 | Methods and Devices for Delivery of Prosthetic Heart Valves and Other Prosthetics - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described. | 04-11-2013 |
20130096671 | METHOD OF IMPLANTING A SELF-EXPANDABLE PROSTHETIC HEART VALVE - A method of implanting a collapsible prosthetic heart valve is disclosed. The prosthetic heart valve includes three biological leaflets mounted within a self-expanding tubular leaflet frame formed of nitinol. The method comprises loading a collapsed prosthetic heart valve into a distal end of a delivery tube. The distal end of the delivery tube is inserted into a vasculature of a patient and positioned proximal to an aortic valve. The prosthetic heart valve is expelled into an annulus of the aortic valve and allowed to self-expand to a first diameter. A balloon is then inflated within the prosthetic heart valve for expanding the prosthetic heart valve to a second diameter, wherein the second diameter is larger than the first diameter, thereby securely implanting the prosthetic heart valve within the annulus of the aortic valve. | 04-18-2013 |
20130096672 | APPARATUS AND METHOD FOR GUIDE-WIRE BASED ADVANCEMENT OF A ROTATION ASSEMBLY - Apparatus is provided, comprising (1) a guide member, (2) a tissue-adjustment mechanism having (a) an upper surface and a lower surface, (b) at least one first opening at the upper surface, (c) at least one second opening at the lower surface, and (4) a channel extending between the first and second openings, the channel facilitating advancement of the tissue-adjustment mechanism along the guide member; and (3) at least one repair chord coupled at a first portion thereof to the tissue-adjustment mechanism and having at least a first end that is configured to be coupled to a portion of tissue of a patient, the repair chord being configured to adjust a distance between the portion of tissue and the tissue-adjustment mechanism, in response to adjustment of the repair chord by the tissue-adjustment mechanism. Other embodiments are also described. | 04-18-2013 |
20130110226 | Tools, Systems, and Methods for Remodeling Tissue | 05-02-2013 |
20130110227 | DELIVERY SYSTEM FOR VASCULAR IMPLANT | 05-02-2013 |
20130116777 | UNITARY QUICK-CONNECT PROSTHETIC HEART VALVEAND DEPLOYMENT SYSTEM AND METHODS - A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps. | 05-09-2013 |
20130123910 | INFLATABLE MINIMALLY INVASIVE SYSTEM FOR DELIVERING AND SECURING AN ANNULAR IMPLANT - A delivery device for an annular implant that includes a balloon expansion mechanism and an annular implant having an adjustable dimension. The balloon expansion mechanism includes an inflation tube attached to a non-occluding balloon collar which is supported by trusses radially extending from a trocar. The annular implant further includes a flexible ring core, contiguous coiled spacers, and anchoring blocks. The flexible ring core is adjusted via a cinching mechanism. The anchoring blocks are spaced along the ring core by the contiguous coiled spacers, which keeps the distance between each pair of anchoring blocks equidistant as the ring core diameter is manipulated by the device user. The annular implant can also include gunbarrel elements housed in the trocar. Each gunbarrel element contains a gunbarrel pusher which drives an attachment element into the annular implant and annular tissue. | 05-16-2013 |
20130123911 | TRANSAPICAL COLLAPSIBLE VALVE REFERENCE FIXTURE - A device for positioning a reference element during aortic valve implantation surgery. The device includes a first extension member having a proximal end and a distal end, a connection member adapted to connect the first extension member to a support, and a coupling having a first end connected to the connection member and a second end connected to the proximal end of the first extension member so that the first extension member is moveable in multiple planes relative to the support. At least one reference datum is operatively connected to the distal end of the first extension member and extends in a straight line, the reference datum being moveable between a first position and a second position to enable precise locating of the reference datum during the aortic valve implantation surgery. | 05-16-2013 |
20130123912 | MEDICAL DEVICE WITH NOSECONE AND NOSECONE TUBE EXTENSION - Medical device delivery systems and methods for making and using medical device delivery systems are disclosed. An example medical device delivery system may include an outer sheath. An inner catheter may be disposed within the outer sheath. The inner catheter may have a distal end. A tube extension may be coupled to the distal end of the inner catheter and may extend distally therefrom. The tube extension may include a crush resistance support member. | 05-16-2013 |
20130123913 | Catheter-Based Annuloplasty System and Method - A catheter-based annuloplasty system for use in repairing a heart valve having leaflets and a valve annulus, includes a delivery catheter having a proximal end and a distal end, and an expandable stent disposed on the distal end of the catheter. An adjustable annuloplasty ring is disposed on the expandable stent and is configured to expand and contract in response to expansion and contraction of the stent. | 05-16-2013 |
20130123914 | PERCUTANEOUSLY DELIVERABLE HEART VALVE AND METHODS ASSOCIATED THEREWITH - A prosthetic heart valve implantable by catheter without surgery includes a substantially “dry” membrane or tissue material. In at least one embodiment, the tissue is folded in a dry state to form a tissue leaflet assembly that is then attached to a frame to form an implantable prosthetic heart valve. Alternatively, one or more tissue leaflets are operatively associated with a frame to form an implantable prosthetic heart valve. The implantable prosthetic heart valve is subsequently pre-mounted on an integrated catheter delivery system. The catheter delivery system that includes the implantable prosthetic heart valve is then packaged and transported while the tissue remains dry. The implantable prosthetic heart valve, while remaining substantially dry, can then be implanted into the receiving patient. | 05-16-2013 |
20130123915 | DEVICE FOR THE IN SITU DELIVERY OF HEART VALVES - A device for deploying a cardiac valve prosthesis includes a distal valve holder portion and a shaft extending towards the valve holder portion. The shaft is selectively bendable to a curved shape to vary the spatial orientation of the valve holder portion with respect to the desired implantation site. | 05-16-2013 |
20130131789 | DEVICE AND METHOD FOR BLOCKING PIPELINES, ESPECIALLY UNDER THE SEA - Transcorporal delivery system and method for valve replacement surgery that is minimally invasive. | 05-23-2013 |
20130131790 | METHODS OF IMPLANTING MINIMALLY-INVASIVE PROSTHETIC HEART VALVES - Expandable prosthetic heart valves for minimally invasive valve replacement are disclosed. In one preferred embodiment, an expandable prosthetic heart valve includes a support stent comprising an expandable tubular base along an inflow end and three upstanding commissure posts along an outflow end. The three commissure posts are spaced at 120 degree intervals with gaps therebetween. The prosthetic heart valve further includes a tubular flexible member having a prosthetic section and a fabric section. The prosthetic section is connected to the three commissure posts and defines three leaflets, preferably formed of pericardial tissue. The fabric section is sutured to the expandable tubular base. The tubular base may be formed with a shape memory material and is sized for deployment with an annulus of a native aortic valve. After deployment, the three commissure posts support the leaflets above the tubular base for replacing the function of the native aortic valve. In one variation, flanges may be provided on the support stent for improving attachment of the support stent to the host tissue. | 05-23-2013 |
20130144379 | IMPLANTABLE WIRELESS SENSOR SYSTEMS - In some embodiments, a cardiac monitoring system includes multiple sensors configured for implantation in a cardiovascular system of a user. Each sensor includes a sensing unit configured to be disposed in sensory communication with the location for measuring a biological parameter in the at least one heart chamber. The sensing unit is also configured to generate a sensory signal associated with the biological parameter. Each sensor also includes a wireless transceiver configured to receive the sensory signal from the sensing unit. The wireless transceiver is further configured to wirelessly transmit the sensory signal to an external processing device disposed outside a body of the user. The external processing device monitors, based on the sensory signal received from at least two sensors from the plurality of sensors, cardiac health associated with at least one of an implanted device or a surgery. | 06-06-2013 |
20130144380 | VASCULAR IMPLANT AND DELIVERY SYSTEM - A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired. | 06-06-2013 |
20130144381 | REPLACEMENT HEART VALVES, DELIVERY DEVICES AND METHODS - A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve. | 06-06-2013 |
20130150954 | FORCE-BASED HEART VALVE SIZER - A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals. | 06-13-2013 |
20130150955 | ACTIVE HOLDER FOR ANNULOPLASTY RING DELIVERY - An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle. | 06-13-2013 |
20130158653 | MEDICAL DEVICE DELIVERY SYSTEMS - Medical device delivery systems and methods for making and using medical device delivery systems are disclosed. An example medical device delivery system may include an outer sheath. An inner catheter may be disposed within the outer sheath. The inner catheter may have a distal end. A tube extension may be coupled to the distal end of the inner catheter and may extend distally therefrom. The tube extension may be configured to shift between a first elongated configuration and a second shortened configuration. | 06-20-2013 |
20130158654 | HEART VALVE REPLACEMENT CATHETER - The disclosure pertains to catheter-based delivery system for intravascular heart valve replacement and methods of use thereof. In addition to the replacement heart valve and associated positioning and installation components, the delivery catheter of the system includes a deployable filter element, an actuator for the deployable filter element, and a fluid expandable balloon located proximate the distal end of the delivery catheter. The delivery catheter may be capable of carrying out a valvuloplasty and/or a determination of a distance within a patient. | 06-20-2013 |
20130158655 | MEDICAL DEVICE HANDLE - A medical device handle may include an elongated handle housing, a rotatable collar disposed about the handle housing, a rotatable control knob disposed about the collar, and a slidable door disposed about the collar. The door may be rotatably locked to the collar to prevent relative rotation between the door and the collar. The door may slidable from a closed position to a first open position, and slidable from the first open position to a second open position. | 06-20-2013 |
20130158656 | APPARATUS FOR ENDOVASCULARLY REPLACING A HEART VALVE - An apparatus for endovascular replacement of a heart valve may include first and second members which are releasably attached to each other such that the second member participates in engaging the first member with a locking element which cooperates with the first member to lock an expandable anchor of the replacement heart valve in a deployed configuration. Prior to locking and removal of the second member, the locking element may be prevented from engaging the first member by a portion of the second member. Following locking, the second member may be removed. | 06-20-2013 |
20130166020 | SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE - An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member, a constricting member, and a spacer which may be used for smaller sized heart valves. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the heart valve. The support member has a base and a recess adapted to receive an end of the heart valve. The support member and the compression member are movable toward one another to compress the heart valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed heart valve from the second open end of the compression member for loading into a delivery device. | 06-27-2013 |
20130172990 | METHOD AND SYSTEM FOR PLICATING TISSUE IN A MINIMALLY INVASIVE MEDICAL PROCEDURE FOR THE TREATMENT OF MITRAL VALVE REGURGITATION - A system and method for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular or adjacent tissue each fixed by a retainer is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a crossing catheter having a prolapseable or curved tip. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. Third, the plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a “C” shaped retainer with deformable ends is deployed by the plication device in order to retain the plicated tissue in the plicated form. | 07-04-2013 |
20130172991 | PROSTHETIC VASCULAR CONDUIT AND ASSEMBLY METHOD - A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve. | 07-04-2013 |
20130172992 | TECHNIQUES FOR PERCUTANEOUS MITRAL VALVE REPLACEMENT AND SEALING - Apparatus and methods are described including a prosthetic valve support ( | 07-04-2013 |
20130184811 | Device and Method for Replacing Mitral Valve - A prosthetic mitral valve assembly and method of inserting the same is disclosed. In certain disclosed embodiments, the prosthetic mitral valve assembly has a flared upper end and a tapered portion to fit the contours of the native mitral valve. The prosthetic mitral valve assembly can include a stent or outer support frame with a valve mounted therein. The assembly can be adapted to expand radially outwardly and into contact with the native tissue to create a pressure fit. One embodiment of a method includes positioning the mitral valve assembly below the annulus such that the annulus itself can restrict the assembly from moving in an upward direction towards the left atrium. The mitral valve assembly is also positioned so that the leaflets of the mitral valve hold the assembly to prevent downward movement of the assembly towards the left ventricle. | 07-18-2013 |
20130190859 | SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE - An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device. | 07-25-2013 |
20130197629 | Inversion Delivery Device And Method For A Prosthesis - A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations. | 08-01-2013 |
20130204356 | Transcatheter Valve Delivery Systems and Methods - Delivery devices and methods for percutaneously delivering a prosthetic valve to the heart of a patient. These prosthetic valves may be configured to provide complimentary features that promote optimal placement of the prosthetic valve in a native heart valve, such as the aortic valve, mitral valve, pulmonic valve, and/or tricuspid valve. The delivery device includes a release sheath assembly housed within an outer delivery sheath. A release sheath component of the assembly captures a portion of the prosthetic valve to the delivery device, and effectuates complete release of the prosthetic valve with retraction of the outer sheath. | 08-08-2013 |
20130204357 | Stentless Support Structure - A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve. | 08-08-2013 |
20130211508 | SEQUENTIALLY DEPLOYED TRANSCATHETER MITRAL VALVE PROSTHESIS - A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab. | 08-15-2013 |
20130211509 | METHOD FOR IMPLANTING PROSTHETIC VALVE - A method for implanting a prosthetic valve apparatus in a novel location which replaces the function of a native diseased valve after an Alfieri procedure. The prosthetic valve apparatus includes a one way valve and an expandable valve seating. anchoring and securing apparatus in a newly created orifice near or at the center of the anterior valve leaflet. The prosthetic valve apparatus also causes the sealing of the native valve and thus results in a solution for paravalvular leakage and regurgitation. | 08-15-2013 |
20130211510 | METHODS AND DEVICES FOR TRANSCATHETER CERCLAGE ANNULOPLASTY - Devices, apparatus, and methods for catheter-based repair of cardiac valves, including transcatheter-mitral-valve-cerclage annuloplasty and transcatheter-mitral-valve reapposition. In particular, a target and capture device is provided for guiding a cerclage traversal catheter system through a cerclage trajectory, particularly through a reentry site of the cerclage trajectory. The target and capture device provides the user with a target through which the cerclage traversal catheter system must be guided, particularly under imaging guidance, so as to properly traverse the cerclage trajectory at any desired location, particularly at a reentry site. The target and capture device can, further, ensnare and externalize the cerclage traversal catheter system. | 08-15-2013 |
20130218266 | BALLOON EXPANDABLE PLATFORM WITH RETAINING FEATURES FOR A COLLAPSIBLE VALVE - Retainer structures ( | 08-22-2013 |
20130226289 | PERCUTANEOUS ANNULOPLASTY SYSTEM WITH ANTERIOR-POSTERIOR ADJUSTMENT - Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow body member including a plurality of regions. Adjacent regions cooperate with one another to change the body member from an elongate insertion geometry to an annular operable geometry. Adjacent regions are coupled by a biasing element or a stepped connector to allow expansion to an expanded state and contraction to a contracted state in the annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the body member and having a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. An angled ring closure lock allows coupling of the ends of an annuloplasty ring at an apex of a D-shape annular operable geometry. | 08-29-2013 |
20130226290 | METHODS, DEVICES, AND SYSTEMS FOR PERCUTANEOUSLY ANCHORING ANNULOPLASTY RINGS - Apparatus, systems, and methods are provided for percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer tube, an inner body member, and an anchor deployment system. The outer tube includes a plurality of windows and has an axis along its length. The internal body member includes a plurality of anchors formed perpendicular to the axis. The anchor deployment system selectively rotates the internal body member with respect to the axis of the outer tube. The rotation deploys the plurality of anchors through the plurality of windows. | 08-29-2013 |
20130231735 | HYDRAULIC DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE DEVICES AND ASSOCIATED METHODS - Systems, apparatuses, and methods for treating native heart valves are disclosed herein. A system for delivering a prosthetic device into a heart of a patient includes an elongated catheter body and a delivery capsule. The delivery capsule can be hydraulically driven to deploy at least a portion of a prosthetic heart valve device. The delivery capsule can release the prosthetic heart valve device at a desired treatment site in a patient. | 09-05-2013 |
20130231736 | Catheter Delivery System For Stent Valve - A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion. | 09-05-2013 |
20130238087 | METHOD OF DELIVERING A PROSTHETIC HEART VALVE - A method of delivering a prosthetic heart valve to a native aortic valve is disclosed. The prosthetic heart valve comprises a radially compressible and expandable metallic stent and a flexible valvular structure. A delivery system comprises a selectively steerable section and a pusher member extending through a central lumen of the steerable section. The prosthetic heart valve is compressed and inserted into a distal end portion of the delivery system. The delivery system and prosthetic heart valve are advanced through a femoral artery and around an aortic arch. A pull wire is actuated for selectively controlling a curvature of the steerable section during advancement around the aortic arch. The pusher member is advanced for ejecting the prosthetic heart valve from the delivery system into the native aortic valve, wherein the prosthetic valve self-expands after ejection. | 09-12-2013 |
20130238088 | METHOD FOR IMPLANTING A CARDIOVASCULAR VALVE - A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve. | 09-12-2013 |
20130238089 | METHOD FOR ANCHORING A MITRAL VALVE - An artificial mitral valve is anchored in the left atrium by placing the valve between the annulus of the natural mitral valve and an artificial annulus. The artificial annulus is formed by inserting a tool into the coronary sinus, and adjusting the tool to force the wall of the left atrium to form an annulus above the artificial valve, this locking it in place and forming a hemostatic seal. | 09-12-2013 |
20130245750 | BIOMATERIALS WITH ENHANCED PROPERTIES AND DEVICES MADE THEREFROM - Biomaterials with enhanced properties such as improved strength, flexibility, durability and reduced thickness are useful in the fabrication of biomedical devices, particularly those subjected to continuous or non-continuous loads where repeated flexibility and long-term durability are required. These enhanced properties can be attributed to elevated levels of elastin, altered collagen types, and other biochemical changes which contribute to these enhanced properties. Examples of devices which would be improved by use of such tissue include heart valves, including percutaneous heart valves, and vascular grafts, patches and the like. Such enhanced materials can be sourced from specific populations of animals, such as neonatal calves, or in range-fed adult cattle, or can be fabricated or created from cell populations exhibiting such properties. In one embodiment, glutaraldehyde-fixed neonatal pericardial tissue is used to create leaflets in a percutaneous heart valve, and may be used without chemical fixation, with or without processes to remove residual cellular membranes, and utilized as a scaffold material for tissue engineering. | 09-19-2013 |
20130245751 | SYSTEMS AND METHODS FOR ENSURING SAFE AND RAPID DEPLOYMENT OF PROSTHETIC HEART VALVES - A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement. | 09-19-2013 |
20130245752 | DEVICE INTENDED TO BE ATTACHED TO OR INTERCONNECTED WITH A CATHETER, CATHETER AND METHOD - A device is intended to be attached to or interconnected with a medical implant, and intended to be attached to or interconnected with a catheter. The catheter is intended for implanting the implant. A catheter is suited for receiving at least one such device and a method provides a delivery implement with an implant detachably disposed in the device. | 09-19-2013 |
20130253639 | HEART VALVE CHORDAE REPLACEMENT METHODS AND APPARATUS - Apparatus for attaching a prosthetic tether between a leaflet of a patient's heart valve and another portion of the patient's heart to help prevent prolapse of the leaflet and/or to otherwise improve leaflet function. The apparatus can be used with relatively low invasiveness of the patient's body. The apparatus releasably clamps the leaflet during attachment of the tether to the leaflet. The apparatus may include an integrated display for indicating how extensively the leaflet is being clamped, as well as structure for stabilizing the leaflet for better clamping. The apparatus may enter the heart through an aperture in the wall of the heart, and may include structure for helping to reduce blood leakage from that aperture. The apparatus may be able to enter the heart by following a guide wire. The apparatus may include various means for attaching the tether to the leaflet. | 09-26-2013 |
20130253640 | RETAINING MECHANISMS FOR PROSTHETIC VALVES - Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native leaflets of a valve. A locking member is used to couple both ends of the support member, forming a support band. An expandable prosthetic heart valve is delivered into the native heart valve and expanded while the expandable prosthetic valve is at least partially within the support band, thereby causing one or more of the native leaflets of the native heart valve to be frictionally secured between the support band and the expanded prosthetic heart valve. | 09-26-2013 |
20130253641 | METHODS FOR ACCESSING A LEFT VENTRICLE - Two minimally invasive therapeutic procedures, particularly for patients with congestive heart failure, may be performed separately or together. One procedure involves providing a valved passageway through the patient's left ventricular wall at the apex of the patient's heart and advancing instruments through the valved passageway to connect the valve leaflets of the patient's heart valve, e.g. the mitral valve. The second procedure involves advancing a pacing lead and a pacing lead implanting device through a trocar in the patient's chest and implanting the pacing lead on an exposed epicardial region of the patient's heart wall. The pacing lead has a penetrating electrode which is secured within the heart wall. Improved devices for these procedures include a minimally invasive grasping device for heart leaflets, a leaflet connector with artificial cordae tendenae and a pacing lead implant instrument. | 09-26-2013 |
20130261737 | Dual Valve Prosthesis for Transcatheter Valve Implantation - A dual valve prosthesis having first and second prosthetic valve sections is disclosed. The first prosthetic valve section includes a stent structure with a first prosthetic valve secured therein and the second prosthetic valve section includes an annular frame with a second prosthetic valve secured therein. When the dual valve prosthesis is in an expanded configuration, the annular frame extends from the stent structure such that the first and second prosthetic valves are laterally offset from each other. In a method in accordance herewith, the first and second prosthetic valve sections include prosthetic aortic and mitral valves, respectively, and the dual heart valve prosthesis is configured to replace both the native aortic and mitral valves of the heart in a single transcatheter heart valve implantation procedure. | 10-03-2013 |
20130261738 | Dual Valve Prosthesis for Transcatheter Valve Implantation - A dual valve prosthesis having first and second prosthetic valve components with a linkage that connects the first and second prosthetic valve components together is disclosed. Each of the first and second prosthetic valve components includes a stent structure with a prosthetic valve secured therein. In a disclosed method, the first and second prosthetic valve components include prosthetic mitral and aortic valves, respectively, and the dual heart valve prosthesis is configured to replace both the native mitral and aortic valves of the heart in a single transcatheter heart valve implantation procedure. The linkage between the first and second prosthetic valve components is configured to secure the anterior mitral valve leaflet against a wall of the left ventricle when the dual valve prosthesis is implanted within the heart. | 10-03-2013 |
20130261739 | Dual Valve Prosthesis for Transcatheter Valve Implantation - A dual valve prosthesis having a self-expanding anchoring frame with first and second prosthetic valve assemblies attached to the anchoring frame is disclosed. Each of the first and second prosthetic valve assemblies includes a balloon-expandable stent structure with a prosthetic valve secured therein. In a disclosed method, the first and second prosthetic valve assemblies include prosthetic mitral and aortic valves, respectively, and the dual heart valve prosthesis is configured to replace both the native mitral and aortic valves of the heart in a single transcatheter heart valve implantation procedure. | 10-03-2013 |
20130261740 | Valve Prosthesis - Heart valve prostheses are provided having a self-expanding frame that supports a valve body comprising a skirt and a plurality of coapting leaflets. The leaflets are constructed with four commissure points to reduce the stress and strain applied to the commissure points and to efficiently distribute and transmit forces along the leaflets and to the frame. | 10-03-2013 |
20130261741 | Prosthetic Heart Valves and Devices, Systems and Methods for Prosthetic Heart Valves - Described herein is a unique sutureless heart valve that includes a deployment mechanism having a plurality of fasteners. The plurality of fasteners may be actuated at least two states: a disengaged state wherein said plurality of fasteners are retracted, and an engaged state wherein said plurality of fasteners are extended; and further comprising a deployed state wherein said plurality of fasteners, when extended, are irreversibly locked such that said heart valve is securely deployed at the target surgical site. The valve deployment mechanism comprises a ring assembly comprising a first annular member onto which said plurality of fasteners are associated and a second annular member peripheral to said first annular member and comprising a series of windows through which individual fasteners of said plurality of fasteners project. | 10-03-2013 |
20130261742 | KIT FOR THE MANIPULATION OF IMPLANTABLE MEDICAL DEVICES - A kit for facilitating crimping of a prosthetic heart valve for implantation at an aortic valve site in a human heart, the aortic valve site including a plurality of valve sinuses, the kit comprising a prosthetic aortic heart valve having a tubular structure and a first central axis including an anchoring structure comprising an annular outflow member, an annular inflow member, and a plurality of axial connection formations arranged in pairs angularly distributed around the central axis, and a plurality of leaflets coupled to the anchoring structure and adapted to substantially allow blood flow in a first direction and to substantially prevent blood flow in a second direction. The kit further includes a holder member comprising a first disc support member that includes a central hub and a plurality of bridge elements, wherein the hub and the bridge elements extend axially from opposite sides of the disc support member; and a second ring support member that includes receptacles for coupling with the bridge elements, and a plurality of finger formations protruding axially from the ring member and extending lengthwise along at least a portion of the prosthetic aortic heart valve. | 10-03-2013 |
20130268064 | Heart Valve Prosthesis Recapture Devices - Heart valve prosthesis recapture devices and methods for recapture are disclosed, which can be used for recapturing a partially deployed heart valve prosthesis. The recapture device comprises a recapture sleeve, configured to envelop and collapse a partially deployed heart valve prosthesis. The recapture sleeve comprises a distal end, configured to be securely attached to a guide wire, and a proximal end, comprising an opening along a longitudinal axis of the recapture sleeve. The opening can be configured to expand as it engages the heart valve prosthesis, and be biased toward a closed configuration. An attachment element can interface with the distal end of the recapture sleeve and be securely attached to a guide wire, such as by crimping. The recapture sleeve can include a support structure comprising at least one spine and a plurality of ribs. | 10-10-2013 |
20130268065 | Valve Introducers With Adjustable Deployment Mechanism and Implantation Depth Gauge - Valve introducer systems and methods for implanting heart valve prostheses are disclosed, where a valve introducer includes an adjustable deployment mechanism comprising a deployment element and an implantation depth controlling element having a distal end and an adjustable length. The valve introducer also includes a tubular member having a distal end, configured to deliver a heart valve prosthesis, and a length extending from a fixed reference point. The implantation depth controlling element can comprise an inner and an outer cylinder, such as where the outer cylinder has interior threads, and the inner cylinder has exterior threads. The adjustable deployment element can include a depth gauge, wherein the depth gauge indicates the length the tubular member extends beyond a fixed reference point. In certain embodiments, the adjustable deployment element can also be configured to be secured to a cannula. | 10-10-2013 |
20130268066 | TRANSCATHETER HEART VALVE WITH MICRO-ANCHORS - Methods and devices for treating defective heart valves are disclosed herein. In one exemplary embodiment, a transcatheter heart valve includes an expandable shape memory stent and a valve member supported by the stent. A plurality of micro-anchors can be disposed along an outer surface of the stent for engaging native tissue. The transcatheter heart valve can be configured to be advanced into a dilated valve annulus via a balloon catheter. The balloon can be inflated to expand the transcatheter heart valve from a collapsed diameter to an over-expanded diameter such that the micro-anchors engage tissue along the surrounding valve annulus. After engaging the tissue, the balloon can be deflated and the shape memory stent can retract or recoil toward its predetermined recoil diameter. As the stent recoils, the surrounding tissue is pulled inward by the stent such that the diameter of the valve annulus is reduced. | 10-10-2013 |
20130274870 | Stent Valve, Delivery Apparatus and Method Therefor - A delivery catheter ( | 10-17-2013 |
20130274871 | RECOIL INHIBITOR FOR PROSTHETIC VALVE - A valve loading apparatus is provided for loading a crimped prosthetic valve into a lumen of a delivery system. The valve recoil adapter can counteract recoil of a compressed prosthetic valve, and maintain the valve at its desired crimp diameter. An integrated bioprosthesis/delivery system is provided for delivering a bioprosthesis to a target area within a body lumen is provided. The delivery system includes a valve covering member and a compressing member, which compresses the valve covering member to surround, hold, and/or compress the valve during delivery to the target area. | 10-17-2013 |
20130282110 | VALVE REPLACEMENT SYSTEMS AND METHODS - Systems and methods for medical interventional procedures, including approaches to valve implant. In one aspect, the methods and systems involve a modular approach to treatment. | 10-24-2013 |
20130282111 | Transcatheter Prosthetic Heart Valve Delivery System and Method With Expandable Stability Tube - A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft assembly, a delivery sheath assembly, an outer stability tube, and a handle. The sheath assembly is slidably disposed over the inner shaft, and includes a capsule and a shaft. The capsule compressively contains the prosthesis over the inner shaft. The stability tube is slidably disposed over the delivery sheath, and includes a distal region configured to be radially expandable from a first shape having a first diameter to a second shape having a larger, second diameter. In a first delivery state, the distal region assumes the first shape, providing a low profile appropriate for traversing a patient's vasculature. In a second delivery state, the distal region has the expanded diameter second shape, sized to receive the capsule, such as when retracting the capsule to implant the prosthesis. | 10-24-2013 |
20130282112 | METHODS OF IMPLANTING A PROSTHETIC HEART VALVE - The present disclosure concerns embodiments and methods of use of an introducer that is adapted to facilitate insertion of a prosthetic device, such as a prosthetic heart valve, into a patient's vasculature. In one embodiment, the introducer comprises an elongated body defining a central lumen extending between distal and proximal ends of the body. The introducer body can also have a longitudinally extending gap extending along the length of the body between the distal end proximal ends. The gap in the introducer allows a user to place the introducer around implant sutures by passing the sutures through the gap and into the central lumen. Similarly, the gap allows the introducer to be easily removed from the sutures and/or a delivery device by passing them outwardly through the gap. | 10-24-2013 |
20130289716 | APPARATUS AND PROCEDURE FOR TRAPPING EMBOLIC DEBRIS - A collapsible and deployable filter for blocking debris and passing blood in a blood vessel in a patient's body, the filter including; a framework of a flexible material, constructed to have a radially compressed state, in which the framework is radially compressed by radial deforming forces, and a radially expanded state to obdurate an artery; and a flexible filter material secured to said framework and having pores dimensioned to prevent the passage of debris therethrough while allowing the passage of blood. The filter has, in the radially expanded state of the framework, a generally conical or frustoconical form with a large diameter end, a small diameter end opposite to the large diameter end, and a side surface extending between the ends. The filter has an opening that is free of filter material at the small diameter end or in the side surface. | 10-31-2013 |
20130289717 | Device And A Method For Augmenting Heart Function - A device, a kit and a method are presented for permanently augmenting the pump function of the left heart. The basis for the presented innovation is an augmentation of the physiologically up and down movement of the mitral valve during each heart cycle. By means of catheter technique, minimal surgery, or open heart surgery implants are inserted into the left ventricle, the mitral valve annulus, the left atrium and adjacent tissue in order to augment the natural up and down movement of the mitral valve and thereby increasing the left ventricular diastolic filling and the piston effect of the closed mitral valve when moving towards the apex of said heart in systole and/or away from said apex in diastole. | 10-31-2013 |
20130289718 | PERCUTANEOUS TRANSCATHETER REPAIR OF HEART VALVES - Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow member including a plurality of segments. Adjacent segments cooperate with one another to change the outer hollow member from an elongate insertion geometry to an annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the outer hollow member. The internal anchor member includes a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. The internal anchor member is configured to move the plurality of anchors with respect to a plurality of windows in the outer hollow member to selectively deploy the plurality of anchors through the respective windows. | 10-31-2013 |
20130297010 | PROSTHETIC IMPLANT DELIVERY DEVICE WITH INTRODUCER CATHETER - A delivery system and a method for deploying a cardiovascular prosthetic implant using a minimally invasive procedure are disclosed. The delivery system comprises an introducer catheter, a delivery catheter having a proximal end and a distal end, and a seal assembly, wherein an outer diameter of the distal end of the delivery catheter is greater than an inner diameter of the distal end of the introducer catheter. | 11-07-2013 |
20130297011 | DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY - A delivery device for a collapsible prosthetic heart valve includes an operating handle and a catheter assembly. The operating handle may include a housing defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, a deployment actuator coupled to the housing and rotatable relative to the housing, and a coupling assembly rotationally fixed to the deployment actuator. The catheter assembly may include a first shaft around which a compartment is defined and a distal sheath operatively connected to the carriage assembly. Movement of the carriage assembly in the longitudinal direction in the movement space may move the distal sheath between the closed condition and the open condition. The coupling assembly may have an engaged position in which rotation of the deployment actuator moves the carriage assembly, and a disengaged position in which rotation of the deployment actuator does not move the carriage assembly. | 11-07-2013 |
20130297012 | DELIVERY SYSTEM DEFLECTION MECHANISM - A delivery device for a prosthetic heart valve includes a proximal sheath and a distal sheath. The proximal sheath has a distal end disposed at an oblique angle relative to the longitudinal axis of the proximal sheath, and the distal sheath has a proximal end disposed at an oblique angle relative to the longitudinal axis of the distal sheath. The distal end of the proximal sheath and the proximal end of the distal sheath mate so that rotation of the distal sheath relative to the proximal sheath causes the distal sheath to deflect from coaxial alignment with the proximal sheath. Deflection of the distal sheath relative to the proximal sheath enables the prosthetic valve to be axially aligned with the native valve annulus for deployment. | 11-07-2013 |
20130297013 | HYPOTUBE SHAFT WITH ARTICULATION MECHANISM - A delivery device for a prosthetic heart valve includes a shaft, a sheath, and a pull wire. The shaft has a proximal end, a distal end, and a longitudinal axis. The sheath is attached to the shaft and is rotatable about an axis transverse to the longitudinal axis of the shaft. The pull wire is mechanically coupled to the sheath such that movement of the pull wire rotates the sheath relative to the shaft. The sheath may be in a first position relative to the shaft when a distal end of the pull wire is in a first position and may be in a second position when the distal end of the pull wire is in a second position. Deflection of the sheath relative to the shaft enables a prosthetic valve to be axially aligned with the native valve annulus for deployment. | 11-07-2013 |
20130304197 | CARDIAC VALVE MODIFICATION DEVICE - In an aspect, there is a prosthetic valve modification device adapted for endovascular delivery to a cardiac valve. The valve includes first and second support elements each having a collapsed delivery configuration and a deployed configuration. There are at least two bridging members extending from the first support element to the second support element, the bridging members having a delivery configuration and a deployed configuration. The bridging members either extend radially inward from the first and second support elements in the deployed configuration or are entirely straight and devoid of any visible curvature when in said deployed configuration. | 11-14-2013 |
20130304198 | Left Heart Assist Device and Method - A device, a kit and a method is presented for permanently augmenting the pump function of the left heart. The mitral valve plane is assisted in a movement along the left ventricular long axis during each heart cycle. The very close relationship between the coronary sinus and the mitral valve is used by various embodiments of a medical device providing this assisted movement. By means of catheter technique an implant is inserted into the coronary sinus, the device is augmenting the up and down movement of the mitral valve and thereby increasing the left ventricular diastolic filling when moving upwards and the piston effect of the closed mitral valve when moving downwards. | 11-14-2013 |
20130310923 | PERCUTANEOUS HEART VALVE DELIVERY SYSTEMS - Embodiments described herein address the need for improved catheter devices for delivery, repositioning and/or percutaneous retrieval of the percutaneously implanted heart valves. One embodiment employs a plurality of spring-loaded arms releasably engaged with a stent frame for controlling expansion for valve deployment. Another embodiment employs a plurality of filaments passing through a distal end of a pusher sleeve and apertures in a self-expandable stent frame to control its state of deployment. With additional features, lateral positioning of the stent frame may also be controlled. Yet another embodiment includes plurality of outwardly biased arms held to complimentary stent frame features by overlying sheath segments. Still another embodiment integrates a visualization system in the subject delivery system. Variations on hardware and methods associated with the use of these embodiments are contemplated in addition to those shown and described. | 11-21-2013 |
20130310924 | SYSTEMS AND METHODS FOR TREATING LUMENAL VALVES - The present embodiments relate to systems and methods for treating lumenal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of lumenal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter. | 11-21-2013 |
20130310925 | Balloon Mitral Spacer - A heart valve implant according to one embodiment may include a shaft and an anchor disposed on one end of the shaft, the anchor configured to engage tissue. The heart valve implant may further include an expandable member disposed over at least part of the shaft, the expandable member comprising a resiliently deformable internal layer and a resiliently deformable external layer disposed over the internal layer, the expandable member defining a chamber and being configured to receive an inflation medium in the chamber to expand the expandable member, the expandable member further configured to deform upon contact with at least a portion of at least one leaflet of a heart valve to at least partially conform to the shape of the leaflet. | 11-21-2013 |
20130310926 | LOW PROFILE TRANSCATHETER HEART VALVE - An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame. | 11-21-2013 |
20130317602 | APPARATUS AND METHOD FOR IMPLANTING COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES - Apparatus for delivering a prosthetic heart valve into a patient by means that are less invasive than conventional open-chest, open-heart surgery. The prosthetic valve may be collapsed while in a delivery device. When the valve reaches the desired implant site in the patient, the valve can be released from the delivery device, which allows the valve to re-expand to the configuration in which it can function as a heart valve. For example, the delivery device may be constructed to facilitate delivery of the prosthetic valve into the patient via the apex of the patient's heart. | 11-28-2013 |
20130325110 | SYSTEMS AND METHODS FOR PLACING A COAPTING MEMBER BETWEEN VALVULAR LEAFLETS - The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. Finally, there is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets. | 12-05-2013 |
20130325111 | PRE-ASSEMBLED BIOPROSTHETIC VALVE AND SEALED CONDUIT - A valved conduit including a bioprosthetic valve, such as a heart valve, and a tubular conduit sealed with a bioresorbable material. The bioprosthetic heart valve includes prosthetic tissue that has been treated such that the tissue may be stored dry for extended periods without degradation of functionality of the valve. The bioprosthetic heart valve may have separate bovine pericardial leaflets or a whole porcine valve. The sealed conduit includes a tubular matrix impregnated with a bioresorbable medium such as gelatin or collagen. The valved conduit is stored dry in packaging in which a desiccant pouch is supplied having a capacity for absorbing moisture within the packaging limited to avoid drying the bioprosthetic tissue out beyond a point where its ability to function in the bioprosthetic heart valve is compromised. The heart valve may be sewn within the sealed conduit or coupled thereto with a snap-fit connection. | 12-05-2013 |
20130325112 | MINIMALLY-INVASIVE CARDIAC-VALVE PROSTHESIS - A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site. | 12-05-2013 |
20130325113 | PERCUTANEOUS POSITIONING DEVICE - A system including a positioning member ( | 12-05-2013 |
20130331929 | Means for Controlled Sealing of Endovascular Devices - Expandable sealing means for endoluminal devices have been developed for controlled activation. The devices have the benefits of a low profile mechanism (for both self-expanding and balloon-expanding prostheses), contained, not open, release of the material, active conformation to the “leak sites” such that leakage areas are filled without disrupting the physical and functional integrity of the prosthesis, and on-demand, controlled activation, that may not be pressure activated. | 12-12-2013 |
20130331930 | SYSTEMS FOR IMPLANTING ANNULOPLASTY RINGS WITH MICROANCHORS - Disclosed systems for implanting annuloplasty rings and other prosthetic devices can comprise a plurality of microanchors, sutures threaded through the microanchors, the sutures passing through the prosthetic device, individual microanchor guides, such as tubes or spears, for each microanchor that contain the microanchors during delivery and allow for positioning and deployment of the microanchors into annular tissue. The systems can also comprise a bracket that is temporarily coupled to the prosthetic device, holds the plurality of microanchor guides in position relative to one another and relative to the prosthetic device, and/or guides the sutures passing through the prosthetic device. The prosthetic device can include suture locking mechanisms to secure the prosthetic device to the sutures and to the implanted microanchors after the deployment devices have been removed. | 12-12-2013 |
20130331931 | Apparatus for Replacing a Native Heart Valve and Method of Making the Same - An apparatus for replacement a native heart valve is herein provided. The apparatus includes a replacement heart valve, an expandable anchor, and a plurality of rivets. The expandable anchor comprises a woven braid structure that surrounds at least a portion of the replacement heart valve and has a plurality of braid intersections. At least some of the braid intersections have rivets extending therethrough. | 12-12-2013 |
20130331932 | Method of Accessing a Carotid Artery of a Patient - Methods for easy, atraumatic access to areas of the vasculature that are otherwise difficult to access, using steerable guide catheters constructed with components that are selected to provide optimal navigability, torque transfer, and push ability for a variety of typical percutaneous access routes. The catheter wall thickness in the deflecting segment of the guide catheter is about 1 French (⅓ mm) or less, and includes a slotted deflection tube, and this construction allows a very tight turning radius which in turn enables guide catheter access to regions of the vasculature that are otherwise inaccessible. | 12-12-2013 |
20130338763 | DEVICES AND METHODS FOR REDUCING CARDIAC VALVE REGURGITATION - The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. Finally, there is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets. | 12-19-2013 |
20130338764 | METHODS, SYSTEMS AND DEVICES FOR CARDIAC VALVE REPAIR - Disclosed are devices and methods for treating regurgitation through a valve in the heart. The devices can include an expandable, fluid-tight bladder configured to be deployed between valve leaflets of the heart valve. The bladder can include an upper portion that extends into the atrium of the heart; a lower portion that extends into the ventricle of the heart; and a middle portion positionable within the line of valve leaflet coaptation that provides a sealing surface for one or more of the leaflets. | 12-19-2013 |
20130345796 | APPARATUS AND METHOD FOR AORTIC PROTECTION AND TAVI PLANAR ALIGNMENT - An assembly for guiding a medical apparatus within a patient includes an elongated shaft and a balloon affixed to the shaft and movable between a collapsed condition and an expanded condition. A mesh material may be affixed to the shaft and movable between a collapsed condition and an expanded condition. The balloon may project away from the shaft when the balloon is in the expanded condition. The mesh material may project away from the shaft when the mesh material is in the expanded condition. | 12-26-2013 |
20130345797 | MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE - A device, kit and method may employ an implantable device (e.g., annuloplasty implant) and a tool to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). Tissue anchors are guided into precise position by an intravascularly deployed anchor guide frame and embedded in an annulus. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in a generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may move a posterior leaflet anteriorly and an anterior leaflet posteriorly, improving leaflet coaptation to eliminate mitral regurgitation. | 12-26-2013 |
20130345798 | METHODS OF VALVE DELIVERY ON A BEATING HEART - A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic annulus in an antegrade fashion through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized. | 12-26-2013 |
20130345799 | VALVE APPARATUS, SYSTEM AND METHOD - A cardiac valve with a first anchor frame and a cover on the first anchor frame for unidirectional flow of a liquid through the valve. | 12-26-2013 |
20130345800 | CARDIAC VALVE PROSTHESIS - A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site. | 12-26-2013 |
20130345801 | FORCE-BASED HEART VALVE SIZER - A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals. | 12-26-2013 |
20130345802 | IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit he implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. | 12-26-2013 |
20130345803 | Methods for Delivering a Heart Valve Prosthesis - The invention provides methods and systems for introducing a delivery device in the heart at or near the apex of the heart, wherein the delivery device includes a prosthesis, advancing the prosthesis to the target site, and disengaging the prosthesis from the delivery device at the target site for implantation. Specifically, the present invention provides valve replacement systems for delivering a replacement heart valve to a target site in or near a heart. The valve replacement system comprises a trocar or other suitable device to penetrate the heart at or near the apex of the heart, a delivery member that is movably disposed within the trocar, and a replacement cardiac valve disposed on the delivery member. The delivery member may further comprise mechanical or inflatable expanding members to facilitate implantation of the prosthetic valve at the target site. | 12-26-2013 |
20140005766 | PERCUTANEOUSLY IMPLANTABLE REPLACEMENT HEART VALVE DEVICE AND METHOD OF MAKING SAME | 01-02-2014 |
20140005767 | SYSTEM TO ASSIST IN THE RELEASE OF A COLLAPSIBLE STENT FROM A DELIVERY DEVICE | 01-02-2014 |
20140005768 | SLEEVE FOR FACILITATING MOVEMENT OF A TRANSFEMORAL CATHETER | 01-02-2014 |
20140005769 | Transcatheter Heart Valve Delivery System With Reduced Area Moment of Inertia | 01-02-2014 |
20140005770 | Catheter Assembly With Valve Crimping Accessories | 01-02-2014 |
20140012367 | BALLOON SIZING DEVICE AND METHOD OF POSITIONING A PROSTHETIC HEART VALVE - A sizing device for a collapsible prosthetic heart valve, the sizing device includes a collapsible and expandable balloon having a proximal end, a distal end. At least one microelectromechanical sensor is coupled to the balloon, the at least one sensor being capable of measuring information related to size and stiffness of tissue. | 01-09-2014 |
20140012368 | DEVICES AND METHODS FOR RETRIEVABLE INTRA-ATRIAL IMPLANTS - Devices and methods to enhance the implantation, retreivability, or repositionability are provided. Embodiments of devices include pivotable sections providing the ability to maintain the device's engagement with a delivery system during implantation where the deliver system approaches an opening of the septum at an angle. Embodiments of devices also include configurations that allow for improved retrieval into a delivery system in the event that a malfunction or a problem with the patients physiology is detected. | 01-09-2014 |
20140012369 | Transcatheter Prosthetic Heart Valve Delivery System with Funnel Recapturing Feature and Method - A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment. | 01-09-2014 |
20140012370 | METHODS OF IMPLANTING A UNIT IN A TUBULAR ELEMENT WITH A WALL - The implant implantation unit ( | 01-09-2014 |
20140018910 | ADJUSTABLE PROSTHETIC VALVE IMPLANT - A prosthetic implant for treating a diseased aortic valve is described. The prosthetic implant includes a substantially tubular body configured to be positioned in an aorta of a patient, at or near the patient's aortic valve. The body includes a lumen extending through the body; and an adjustable frame surrounding the lumen. The prosthetic implant further includes at least one adjustable element located in or on the body and extending at least partially around a circumference of the lumen. The at least one adjustable element is transformable, in response to application of an activation energy, from a first configuration to a second configuration. The at least one adjustable element may engage at least one of a root of the aorta, an annulus of the aortic valve, and the patient's left ventricle, when the at least one adjustable element is in the second configuration. | 01-16-2014 |
20140018911 | Low Profile Heart Valve Delivery System and Method - A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent. | 01-16-2014 |
20140018912 | Method and Apparatus Useful for Transcatheter Aortic Valve Implantation - A guide catheter ( | 01-16-2014 |
20140018913 | METHODS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN - A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like. | 01-16-2014 |
20140018914 | OVER-WIRE IMPLANT CONTRACTION METHODS - Apparatus is provided that includes an implant structure, which includes a contracting mechanism, which includes a rotatable structure, arranged such that rotation of the rotatable structure contracts the implant structure. A longitudinal member is coupled to the contracting mechanism. A tool for rotating the rotatable structure is configured to be guided along the longitudinal member, to engage the rotatable structure, and to rotate the rotatable structure in response to a rotational force applied to the tool. Other embodiments are also described. | 01-16-2014 |
20140031922 | Delivery Catheter With Distal Moving Capsule for Transapical Prosthetic Heart Valve Delivery - Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging. | 01-30-2014 |
20140031923 | Trans-Aortic Surgical Syringe-Type Device for Deployment of a Prosthetic Valve - Prosthetic valve introducer systems and methods for deploying a heart valve prosthesis within a body lumen are disclosed. In certain embodiments, the valve introducer can include a delivery shaft to house a prosthetic valve and a distal tip, and a deployment element to push a prosthetic valve out of the distal tip of the delivery shaft. The valve introducer can include at least one finger gripping element. The delivery shaft can be inserted into a body lumen and advanced to a desired deployment location. In certain embodiments, the prosthetic valve can be deployed by pushing the deployment element in a distal direction, thereby pushing the prosthetic valve out of the distal tip of the delivery shaft. | 01-30-2014 |
20140031924 | EVERTING TRANSCATHETER VALVE AND METHODS - Described embodiments are directed toward centrally-opening, leaflet valve devices and systems for transcatheter delivery having a two-piece valve body as well as methods of making and delivering the two-piece valve devices. A transcatheter valve comprises a collapsed configuration and an expanded configuration. The transcatheter valve can further comprise an everted configuration and a non-everted configuration. | 01-30-2014 |
20140031925 | SYSTEMS AND METHODS FOR TRANSCERVICAL AORTIC VALVE TREATMENT - Devices and methods are configured to allow transcervical or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure. | 01-30-2014 |
20140031926 | Device and Method for Heart Valve Repair - The invention provides a device ( | 01-30-2014 |
20140039607 | MITRAL VALVE LEAFLET CLIP - A device for gathering tissue of a heart valve leaflet may include an outer tube extending in an elongation direction and having an open distal end, a capture tool movable in the outer tube between a contained position and a use position, and a tissue securing component disposed at a distal end of the outer tube and adapted to be applied to captured tissue of the heart valve leaflet to hold the captured tissue in a gathered configuration. The outer tube may have an inner surface and a lumen extending therethrough. The capture tool may be operable to capture tissue of the heart valve leaflet and to draw the captured tissue into the outer tube in the gathered configuration. The tissue securing component may be a suture having a looped portion. At least part of the looped portion may extend through a lumen of at least one support tube. | 02-06-2014 |
20140039608 | APPARATUS AND METHOD FOR HEART VALVE REPAIR - A device for gathering tissue of a heart valve leaflet may include an outer tube extending in an elongated direction, a capture tool moveable in the outer tube between a contained position and a use position, and a tissue securing component disposed at a distal end of the outer tube and adapted to be applied to tissue captured by the capture tool and to hold the captured tissue in a gathered configuration. The capture tool may include two grasping members that are moveable relative to one another in the elongated direction. Each grasping member may have a proximal portion and a plurality of fingers or barbs. The grasping members may be operable to capture tissue of the heart valve leaflet therebetween and to draw the captured tissue into the outer tube in the gathered configuration. | 02-06-2014 |
20140039609 | HOLDERS FOR PROSTHETIC HEART VALVES - An improved holder and storage system for prosthetic heart valves that pre-shields or pre-constricts the commissure posts of the valve to prevent suture looping. Pre-shielding and pre-constriction mean at the time of manufacture, so that the valves are stored with the commissure posts shielded and/or constricted. The holders may have solid legs that directly contact and constrict and hold the commissure posts without the use of sutures in tension that might creep over the time in storage. The holder may have a base in contact with the inflow end and a shaft portion that projects through the valve leaflets and cooperates with movable legs on the outflow end of the valve in contact with the commissure posts. The holders may, alternatively, have flexible leg members that extend through the valve and have distal end portions configured to extend over and shield the tips of commissure posts. | 02-06-2014 |
20140039610 | Transcatheter Prosthetic Heart Valve Post-Dilatation Remodeling Devices and Methods - A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks. | 02-06-2014 |
20140039611 | TRANSCATHETER MITRAL VALVE PROSTHESIS - A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart. | 02-06-2014 |
20140039612 | Method for Stabilizing a Cardiac Valve Annulus - A method for stabilizing a cardiac valve annulus is provided. The method includes intravascularly delivering a prosthesis to a region of a cardiac valve, expanding the prosthesis to secure the prosthesis to the region of the cardiac valve, and reducing the inner diameter of the prosthesis to form the region of the cardiac valve into a predefined shape. | 02-06-2014 |
20140046434 | VALVE PROSTHESIS AND KIT - Described is a valve prosthesis comprising: an annular structure, and a plurality of valve leaflets, and a plurality of anchoring members attached around the annular structure, the anchoring members including: a web portion coupled to the annular structure and extending axially thereto, and two end portions at axially opposed sides of the web portion, the end portions having: an insertion condition for insertion of the prosthesis, wherein the end portions are aligned to the web portion and extend axially with respect to the annular structure; and an anchoring condition for anchoring the prosthesis, wherein the end portions extend at an angle to the web portion radially outwardly of the annular structure to provide anchoring of the prosthesis proximally and distally, respectively, of the annulus, and wherein one end portion forms an obtuse angle with the web portion. | 02-13-2014 |
20140046435 | STENTED TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY SYSTEM AND METHOD - A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer. | 02-13-2014 |
20140052237 | METHODS AND APPARATUS FOR ENGAGING A VALVE PROSTHESIS WITH TISSUE - A prosthetic valve comprises a self-expanding frame which includes a self-expanding atrial skirt that forms a flanged region, a self-expanding ventricular skirt, and a first self-expanding tab coupled with the ventricular skirt. A receptacle for receiving a valve leaflet is formed by the area bounded by an outer surface of the atrial skirt, an outer surface of the ventricular skirt, and an inner surface of the first tab. The receptacle has a window for receiving the valve leaflet that is defined by a gap between an edge of the flange and a tip of the first tab. The gap is maximized when the tip of the first tab is unconstrained and a base of the first tab is at least partially constrained. The gap is minimized when the tip of the first tab and its base are unconstrained. | 02-20-2014 |
20140052238 | DELIVERY DEVICE HAVING A CURVED SHAFT AND A STRAIGHTENING MEMBER FOR TRANSCATHETER AORTIC VALVE IMPLANTATION - A delivery device ( | 02-20-2014 |
20140052239 | CONVEYING APPLIANCE WITH VALVE LOCATING FUNCTION FOR USE DURING PERCUTANEOUS AORTIC VALVE REPLACEMENT OPERATION - A conveying appliance with valve locating function for use during percutaneous aortic valve replacement operation includes a conveying rod ( | 02-20-2014 |
20140052240 | DEVICES AND METHODS FOR DELIVERY OF VALVE PROSTHESES - A valve prosthesis and implantation device, and methods for use are provided. The devices described herein may be used for transcatheter delivery of an aortic valve prosthesis or transapical delivery of a mitral valve prosthesis. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis, reducing the extent of imaging needed during the implantation procedure. | 02-20-2014 |
20140052241 | GUIDED DELIVERY OF PROSTHETIC VALVE - An image-guided prosthetic valve deployment system employs a prosthetic valve ( | 02-20-2014 |
20140058502 | INTEGRATED HEART VALVE DELIVERY SYSTEM - Embodiments of the present disclosure provide a delivery apparatus for delivering a prosthetic heart valve to a native valve site via the human vasculature without the need for a separate introducer sheath. The delivery apparatus is particularly well-suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a stenotic aortic valve. | 02-27-2014 |
20140067049 | Integrated Dilation Balloon and Valve Prosthesis Delivery System - An integrated balloon dilation and valve prosthesis delivery device is provided having a capsule that is configured to surround a collapsed valve prosthesis and that contains a balloon on an exterior surface. | 03-06-2014 |
20140067050 | Trans-Aortic Delivery System With Containment Capsule Centering Device - Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly which can include a first control mechanism, a second control mechanism, and a decoupling mechanism. The delivery systems can also include a delivery catheter extending from the handle assembly. The delivery catheter can include an outer shaft, which can be controlled by the first control mechanism; a prosthesis containing capsule comprising a proximal capsule portion connected to the outer shaft, and a distal capsule portion releasably coupled to the proximal capsule portion. After deploying a valve prosthesis, the capsule can be closed by activating the decoupling mechanism in the handle to rapidly close the distal and proximal capsule portions together. The delivery system can also include a centering element to guide the distal and proximal capsule portions together. | 03-06-2014 |
20140067051 | SHEATH AND CERCLAGE THREAD FOR MITRAL CERCLAGE ANNULOPLASTY - A sheath and cerclage thread for mitral cerclage annuloplasty, where the cerclage thread is inserted into a lumen created independently from the lumen through which the guide wire is passed. | 03-06-2014 |
20140067052 | Heart Valve Sealing Devices - This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet. | 03-06-2014 |
20140067053 | Devices and Methods for Loading a Prosthesis Onto a Delivery System - A method for loading a prosthesis onto a delivery system includes passing a distal end of a delivery system through a first open end and a second open end of a reducing member. The method includes seating the prosthesis in a piston member of a cap by contacting a first end of the prosthesis with a first surface of the piston member and by contacting a portion of a side of the prosthesis with at least one side wall extending from the periphery of the first surface. Additionally, the method includes inserting the distal end of the delivery system into a center of the prosthesis and an opening defined by the piston member. And the method includes advancing the cap towards a reducing member such that a portion of the prosthesis seated in the piston member advances along an inner surface of the conical wall of the reducing member. | 03-06-2014 |
20140074226 | ANTI-ROTATION LOCKING FEATURE - An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment. | 03-13-2014 |
20140074227 | Transcatheter Prosthetic Heart Valve Delivery Device with Stability Tube and Method - A device for percutaneous delivery of a stented prosthetic heart valve. The device includes a sheath, a handle, and an outer stability tube. The sheath includes a distal capsule and a proximal shaft. The handle has a housing maintaining an actuator mechanism that is coupled to the shaft. The actuator mechanism is configured to selectively move the shaft, and thus the capsule, relative to the housing. The stability tube is coupled to the housing and is coaxially received over the shaft such that the shaft is slidable relative to the stability tube. In a delivery state, the capsule encompasses the prosthetic valve. In a deployed state, the capsule is withdrawn from the prosthetic valve. The shaft slides relative to the stability tube in transitioning from the loaded state to the deployed state. When used with an introducer device, the stability tube frictionally isolates the sheath. | 03-13-2014 |
20140081387 | TAPERED LOADING SYSTEM FOR IMPLANTABLE MEDICAL DEVICES - Loading systems for compressing and loading an implantable medical device into a device chamber of a medical device delivery system are described. The loading systems include an elongate holding chamber within which the intraluminal medical device is disposed. A plunger has one or more attached pushers adapted to axially advance the intraluminal medical device through an intermediate portion of the holding chamber that has a tapered surface, which compresses the intraluminal medical device over a dilator of a medical device delivery system that has been introduced through the distal end of the elongate holding chamber. The elongate holding chamber can be placed within an outer storage container with an appropriate seal to for storage of the intraluminal medical device within the loading system. Methods of preparing an intraluminal medical device for implantation in a patient and kits useful in such methods are also described. | 03-20-2014 |
20140081388 | DEVICE FOR THE IMPLANTATION AND FIXATION OF PROSTHETIC VALVES - A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent ( | 03-20-2014 |
20140081389 | CONFORMAL EXPANSION OF PROSTHETIC DEVICES TO ANATOMICAL SHAPES - A system for expanding a device in a conduit or orifice of a human body includes an expansion device that is movable from a first configuration to a second configuration. External surfaces of the expansion device can collectively have a non-cylindrical cross-section relative to a main axis of the expansion device, such that the external surfaces of the expansion device generally conform to the anatomical shape of the conduit or orifice when the expansion device is in the second configuration. | 03-20-2014 |
20140088691 | TOOL FOR THE ADJUSTMENT OF A PROSTHETIC ANATOMICAL DEVICE - An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment. | 03-27-2014 |
20140088692 | SYSTEMS AND METHODS FOR REPLACING A NATIVE HEART VALVE AND AORTA WITH A PROSTHETIC HEART VALVE AND CONDUIT - A medical device includes an expandable conduit, a prosthetic heart valve and a delivery device, including a balloon catheter. The expandable conduit may include one or more inner or outer sleeves supported by a frame or stent. The sleeve(s) may be a bioprosthetic tissue wrapped, molded or sewn about the frame or stent. Coupled to an end of the expandable conduit is the prosthetic heart valve. The conduit and heart valve may be crimped on the balloon catheter for percutaneous deployment. The frame may be constructed of a balloon-expandable material for the conduit portion and a self-expandable material for the prosthetic heart valve portion. The prosthetic heart valve is anchored at the native heart valve and then the conduit to be expanded into place to protect the aorta. The self-expanding prosthetic heart valve avoids the need for balloon mounting. This provides for a smaller diameter and easier delivery. | 03-27-2014 |
20140088693 | Methods for Treating a Heart Valve, in Particular a Mitral Valve - An apparatus for treating a heart valve apparatus includes at least two anchoring elements designed to be anchored at the annulus and/or heart wall of the valve to be treated. Each anchoring element has a support surface. At least one linking element includes a central branch and two curved side branches, one of which is designed to be engaged on the support surface of an anchoring element, while the other is designed to be engaged on the support surface of another anchoring element, the linking element then being designed to be pivoted to a position such that the anchoring elements interconnect and in which the ends of the central branch are located in the vicinity of the support surfaces. | 03-27-2014 |
20140088694 | TWO-PART PROSTHETIC VALVE SYSTEM - A prosthetic valve system for replacing a native aortic valve exhibiting regurgitation comprises a support structure and a transcatheter heart valve (THV) that is separate from the support structure. The support structure is radially collapsible and expandable, and deployable on an outflow side of the native aortic valve, circumscribing the native leaflets of the aortic valve. The THV is radially collapsible and expandable, and deployable in an annulus of the native aortic valve to frictionally engage the native leaflets between an interior surface of the support structure and the THY. | 03-27-2014 |
20140094903 | IMPLANTATION OF REPAIR CHORDS IN THE HEART - Apparatus is provided, including first and second longitudinal members coupled at respective first portions thereof to tissue surrounding the ventricle. The first portion of at least the first longitudinal member is coupled to a tissue anchor, and respective second portions of the first and second longitudinal members are coupled to respective first and second leaflets of a cardiac valve. The longitudinal members are arranged with respect to the tissue anchor and the portion of tissue surrounding the ventricle in a manner which facilitates adjustment of a degree of tension of the first and second longitudinal members to draw the first and second leaflets together. A longitudinal-member-coupling device is coupled to the first and second longitudinal members, and is advanceable toward a ventricular surface of the first and second leaflets, and responsively to draw together the first and second longitudinal members. Other applications are also described. | 04-03-2014 |
20140094904 | Retrievable Heart Valve Anchor and Method - A method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a catheter to a vicinity of the heart valve; deploying the anchor from the catheter; expanding the anchor to contact tissue at an anchor site; and retrieving the anchor into the catheter. The invention also includes an apparatus for endovascularly replacing a heart valve, including: a catheter; a replacement valve configured to be disposed within the catheter for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the catheter for delivery to a vicinity of the heart valve, to be deployed from the catheter, to be expanded to contact tissue at an anchor site and to be retrieved back into the catheter after having been expanded. | 04-03-2014 |
20140100652 | ATTACHMENT DEVICE AND METHODS OF USING THE SAME - Devices for attaching a first mass and a second mass and methods of making and using the same are disclosed. The devices can be made from an resilient, elastic or deformable materials. The devices can be used to attach a heart valve ring to a biological annulus. The devices can also be used for wound closure or a variety of other procedures such as anchoring a prosthesis to surrounding tissue or another prosthesis, tissue repair, such as in the closure of congenital defects such as septal heart defects, tissue or vessel anastomosis, fixation of tissue with or without a reinforcing mesh for hernia repair, orthopedic anchoring such as in bone fusing or tendon or muscle repair, ophthalmic indications, laparoscopic or endoscopic tissue repair or placement of prostheses, or use by robotic devices for procedures such as those above performed remotely. | 04-10-2014 |
20140107767 | VALVE HOLDER AND LOADING INTEGRATION - A device for holding an implantable medical device includes a jar for receiving the implantable medical device, and a ring coupleable to the jar. The ring has a plurality of channels adapted to receive retaining features of the implantable medical device to stabilize the medical device within the jar. | 04-17-2014 |
20140107768 | SIZING DEVICE AND METHOD OF POSITIONING A PROSTHETIC HEART VALVE - A sizing device for a collapsible prosthetic heart valve includes a collapsible and expandable stent. A microelectromechanical sensor is coupled to the stent, the sensor being capable of collecting information related to the size and stiffness of tissue. | 04-17-2014 |
20140107769 | PRE-SIZED PROSTHETIC CHORDAE IMPLANTATION SYSTEM - A system includes a pre-sized prosthetic chordae, a papillary penetration member, and a female securing member. The pre-sized prosthetic chordae is directly connected to an attachment member. The papillary penetration member extends through both the chordae and the attachment member. The female securing member receives the penetration member. The penetration member is an axis about which the chordae pivot. | 04-17-2014 |
20140107770 | Delivery Systems and Methods of Implantation for Replacement Prosthetic Heart Valve - A delivery system and method for positioning and partially deploying a replacement valve at an implantation site, verifying the location of the replacement valve relative to the implantation site, and retrieving the partially deployed stent for repositioning relative to the implantation site. | 04-17-2014 |
20140107771 | ASSEMBLY COMPRISING A STABILISER AND AN INSTRUMENT TO BE POSITIONED IN OR AROUND A PASSAGE SURROUNDED BY BODY TISSUE - An assembly having a stabiliser and an instrument to be positioned in or around a passage surrounded by body tissue, in particular vascular tissue. The stabiliser is provided with one or more suction mouths running in the shape of a loop, which suction mouths can be operationally connected to suction means in order to suck tightly to tissue close to and around said passage, which may still have to be made. The instrument has a head section for performing operations on vascular tissue. The stabiliser and the instrument are provided with, respectively, an instrument stop provided on the stabiliser and a stabiliser stop provided on the instrument, which, in the stop position when they are in contact with one another, unambiguously define the position of the head section with respect to the position of the loop shape. The instrument can be an applicator for positioning and fixing a fixing device in or around the passage, the head section being equipped for carrying and releasing the fixing device. | 04-17-2014 |
20140114402 | Methods and Devices for Repairing and/or Preventing Paravalvular Leakage Post-Implantation of a Valve Prosthesis - Devices and methods for delivering a sealing element post-implantation of valve prosthesis that functions to occlude or fill gaps present between the valve prosthesis and the native valve tissue, thereby reducing, minimizing, or eliminating leaks there through. In a first method, an injectable material is placed within a native valve sinus to form a sealing element that presses native valve leaflets against an outer surface of a heart valve prosthesis. In a second method, an injectable sealing material or a preformed annular sealing component is positioned between the outer surface or perimeter of a heart valve prosthesis and native heart valve tissue. In a third method, a preformed sealing element or component is placed within a heart valve prosthesis to press the prosthesis against native valve tissue. | 04-24-2014 |
20140114403 | APPARATUS AND METHOD FOR HEART VALVE REPAIR - A device for transcatheter gathering of tissue of a heart valve leaflet may include an elongated tube, a capture tool moveable in the tube between a retracted position and an extended position, a tissue support located within a distal portion of the tube, and a clamping member pivotable in the tube between an open position spaced from the tissue support and a closed position adjacent the tissue support. The clamping member may have a flattened clamping portion and a C-shaped portion that defines a pocket therein. An open side of the C-shaped portion may face the tissue support. The capture tool and the clamping member may be operable to gather and clamp tissue between the tissue support and the clamping member, such that the clamped tissue has a gathered configuration. The device may also include a releasable clip adapted to hold the clamped tissue in the gathered configuration. | 04-24-2014 |
20140114404 | TRANSAPICAL MITRAL VALVE REPAIR DEVICE - Methods and devices for repairing a cardiac valve. A minimally invasive procedure includes creating an access in the apex region of the heart through which one or more instruments may be inserted. The device can implant artificial heart valve chordae tendineae into cardiac valve leaflet tissues to restore proper leaflet function and prevent reperfusion. The device punctures the apex of the heart and travels through the ventricle. The tip of the device rests on the defective valve and punctures the valve leaflet. A suture or a suture/guide wire combination is inserted, securing the top of the leaflet to the apex of the heart. A resilient element or shock absorber mechanism adjacent to the outside of the apex of the heart minimizes the linear travel of the device in response to the beating of the heart or opening/closing of the valve. | 04-24-2014 |
20140114405 | Medical Devices and Delivery Systems for Delivering Medical Devices - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 04-24-2014 |
20140114406 | LOW PROFILE HEART VALVE AND DELIVERY SYSTEM - Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve. | 04-24-2014 |
20140121763 | Prosthetic Mitral Valve and Delivery Method - A valve prosthesis and methods for implanting the prosthesis are provided. The prosthesis generally includes a self-expanding frame and two or more engagement arms. A valve prosthesis is sutured to the self-expanding frame. Each engagement arm corresponds to a native mitral valve leaflet. At least one engagement arm immobilizes the native leaflets, and holds the native leaflets close to the main frame. The prosthetic mitral valve frame also includes two or more anchor attachment points. Each anchor attachment point is attached to one or more anchors that help attach the valve prosthesis to the heart. | 05-01-2014 |
20140121764 | AORTIC VALVE AND CONDUIT GRAFT IMPLANT TOOL - A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica. | 05-01-2014 |
20140121765 | Methods For Transluminal Delivery Of Prosthetic Valves - A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchors may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. A radial restraint, comprising a wire, thread or cuff, may be used to ensure expansion does not exceed the preset diameter. The valve support may optionally comprise a drug elution component. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. A blood pump may be inserted into the catheter to ensure continued blood flow across the implantation site during implantation procedure. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand at the implantation site and the anchor engages the lumen wall. Insertion of the catheter may optionally be performed over a transseptally delivered guidewire that has been externalized through the arterial vasculature. Such a guidewire provide dual venous and arterial access to the implantation site and allows additional manipulation of the implantation site after arterial implantation of the prosthetic valve. Additional expansion stents may be delivered by venous access to the valve. | 05-01-2014 |
20140128963 | Transcatheter Valve Prosthesis Delivery System With Recapturing Feature and Method - A delivery system for percutaneously deploying a valve prosthesis. The system includes a catheter assembly including a delivery sheath capsule and a handle having an oscillating device. The capsule is configured to compressively retain the valve prosthesis during implantation. After the valve prosthesis is partially exposed during implantation, the oscillating device can create a vibratory motion to reduce the friction between the valve prosthesis and the delivery sheath capsule in order to recapture the valve prosthesis. | 05-08-2014 |
20140128964 | Stent Seals and Methods for Sealing an Expandable Stent - Embodiments of the present disclosure are related to devices and techniques for para-valve sealing of an expandable stent-valve implanted using a catheter. In some embodiments, a stent-valve is provided which comprises a seal cuff containing material that swells when contacted by blood. A piercing tool may be included and used to permit a user to puncture the cuff prior to introduction into a patient's body. In some embodiments, the cuff has an integral tubular structure configured to withstand balloon expansion of the stent-valve during or after implantation. | 05-08-2014 |
20140128965 | DEVICES, SYSTEMS AND METHODS FOR REPAIRING LUMENAL SYSTEMS - The disclosure provides des systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed. | 05-08-2014 |
20140128966 | AUTOMATIC SUTURING APPARATUS AND METHODS OF USE - An automatic suturing apparatus comprises triggers that activate suturing and securing of the tissue of a patient. An automatic suturing apparatus also comprises triggers that activate suturing and securing of a valve to tissue of a patient. The automatic suturing apparatus can be used in systems and kits. An automatic suturing apparatus can be used in methods of suturing a tissue or a valve to tissue. | 05-08-2014 |
20140135907 | Medical Device Delivery System and Methods of Delivering Medical Devices - In some embodiments, a medical device delivery system includes a catheter and a retainer. The retainer can be engaged with the medical device to restrain relative movement of the medical device in one or more axial and/or radial directions. A variety of retainers and retainer systems are disclosed, many of which can reliably disengage the medical device from the retainer. Methods for using the medical device delivery system are also described. | 05-15-2014 |
20140135908 | Transcatheter Valve Prosthesis Having a Variable Shaped Cross-Section for Preventing Paravalvular Leakage - A transcatheter valve prosthesis includes a self-expanding tubular stent component and a prosthetic valve disposed within and secured to the stent component. The tubular stent component has a proximal portion, a distal portion, and an intermediate portion between the proximal and distal portions. In a compressed delivery configuration, the tubular stent component has a generally circular cross-section along its length. In an expanded deployed configuration, the proximal and distal portions have a generally circular cross-section while the intermediate portion of the stent component has a generally triangular cross-section with three vertexes that are configured to project into three commissural points of a native valve when the valve prosthesis is implanted in situ. The generally triangular transverse cross-section of the valve prosthesis is formed by pulling or extending selected or particular struts of the stent component radially outwards and then applying heat to heat-set the stent component in the deployed configuration. | 05-15-2014 |
20140135909 | Valve Prosthesis Deployment Assembly and Method - The delivery systems disclosed herein can create simultaneous movement of an inner and an outer sheath of the delivery system. The delivery systems can generally include a handle assembly and a delivery catheter. In certain embodiments, the inner shaft and the outer sheath can be slidably controlled by a control element in the handle. The handle assembly can include a housing with a thumbwheel acting as the control element. In certain embodiments, movement of the inner shaft and the outer sheath can be caused via a gear-type system. In certain embodiments, the handle assembly can include a rotatable housing. A control element can rotate the housing, which can cause a first boss associated with the outer sheath and a second boss associated with the inner shaft to move in opposite directions. | 05-15-2014 |
20140135910 | DEVICE AND METHOD FOR RESHAPING TRICUSPID VALVE ANNULUS - A device for reshaping the tricuspid valve comprises a stent that is deployed in the right ventricular outflow tract (RVOT) adjacent to the tricuspid valve and expanded to a size sufficient to reduce the annular diameter or size of the tricuspid valve, thereby improving coaptation of the leaflets and reducing regurgitation. Embodiments of the device are deliverable percutaneously. | 05-15-2014 |
20140135911 | PROSTHETIC HEART VALVE AND METHOD - A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure. | 05-15-2014 |
20140142688 | Medical Device Delivery System and Methods of Delivering a Medical Device - A medical device delivery system can include a dilator including a tip having a taper in a distal direction, a coupler, and a flap that radially protrudes from the tip. The flap can be configured to bend against a body lumen to cover at least a portion of the delivery system when the dilator is tracked through the body lumen. A medical device delivery system can include a dilator including a tip having a lumen and a coupler having a lumen. The coupler can be configured to securely connect to the tip such that the lumen of the tip is aligned with the lumen of the coupler to allow a guide wire to pass therethrough. Methods for loading a medical device into a delivery catheter are also disclosed. | 05-22-2014 |
20140142689 | DEVICE AND METHOD OF TREATING HEART VALVE MALFUNCTION - An assembly and method for treating heart valve malfunction typically including treating of mitral regurgitation wherein an instrument assembly includes an elongated chord movably disposed within an introductory sheath and including an anchor secured to a distal end thereof. An attendant method includes concurrently introducing the sheath and the chord into the heart chamber through an exterior wall and penetrating and passing the sheath and the chord through the anterior mitral valve leaflet. The sheath and the chord are then extended transversely across the heart chamber and the distal end of the chord is anchored to an opposing portion of the heart wall. The sheath is then withdrawn back along the length of the anchored chord and through the anterior mitral valve leaflet and a securing member connects the proximal end of the chord to the valve leaflet. The chord is secured between the valve leaflet and the opposing heart wall under sufficient tension to maintain an intended positioning of the valve leaflet to overcome mitral regurgitation. | 05-22-2014 |
20140142690 | ADJUSTABLE PROSTHETIC ANATOMICAL DEVICE HOLDER AND HANDLE FOR THE IMPLANTATION OF AN ANNULOPLASTY RING - An adjustable prosthetic anatomical holder system may include an adjustable annuloplasty ring, a ring holder, and a positioning handle. The adjustable annuloplasty ring holder facilitates placement and adjustment of the annuloplasty ring during a cardiac surgical procedure. An optional positioning handle holds the adjustable annuloplasty ring during placement and suturing of the ring. The ring holder is constructed from two members that are slidably fit together in telescopic arrangement to accommodate adjustment of the ring size. | 05-22-2014 |
20140142691 | Mitral Valve Replacement System - The invention concerns a minimally invasive valve repair system ( | 05-22-2014 |
20140142692 | Methods and Apparatus for Percutaneous Aortic Valve Replacement - A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve including a reversibly expandable occluding means surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluding means is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The stent(s) displace the native tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the stent(s) at the aortic annulus with precision and relative ease. | 05-22-2014 |
20140148898 | MITRAL VALVE TREATMENT TECHNIQUES - A method is provided for treating mitral valve regurgitation, including inserting a band around between 90 and 270 degrees of a mitral valve of a heart, including around at least a portion of a posterior cusp of the valve, in a space defined by (a) a ventricular wall, (b) a ventricular surface of the posterior cusp in a vicinity of an annulus of the valve, and (c) a plurality of chordae tendineae of one or more types of chordae tendineae selected from the group consisting of: second-order chordae tendineae and third-order chordae tendineae. The method also includes applying pressure to the posterior cusp by inflating the band. | 05-29-2014 |
20140155989 | Synthetic Chord - Synthetic chord devices and methods for using the same for connecting tissues are provided. Aspects of the synthetic chord device include a flexible cord having an attachment element at both a first and a second end, wherein each attachment element includes a piercing member coupled to a securing member that attaches the flexible cord to a first tissue. At least a portion of the flexible cord can be configured to be secured to a second tissue. Aspects of the invention also include sets of the synthetic chord device with pre-measured flexible cords. The devices and methods of the invention find use in a variety of applications, such as in is applications in which it is desired to repair a heart valve. | 06-05-2014 |
20140155990 | METHODS AND APPARATUS FOR LOADING A PROSTHESIS ONTO A DELIVERY SYSTEM - A device for loading a prosthesis onto a delivery system includes a first housing having a central bore. One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore. | 06-05-2014 |
20140155991 | PROSTHETIC VALVE IMPLANT SITE PREPARATION TECHNIQUES - Prosthetic valves implantation methods and systems, especially as related to preparing the native site of a native stenotic or incompetent aortic valve for receipt of a prosthetic replacement valve are described. The subject tools and associated site preparation techniques may be employed in percutaneous aortic valve replacement procedures. | 06-05-2014 |
20140155992 | TRANSLUMINAL CARDIAC BALL VALVE AND METHOD FOR DEPLOYMENT THEREOF - A transluminal cardiac valve includes an expandable generally tubular cage including when expanded a generally uniform central region, first and second ends each diametrically constricted relative to the central region, a blood impervious region extending from the first end of the cage to within the generally uniform central region, and an inflatable plunger freely disposed and captured within the cage when inflated. | 06-05-2014 |
20140155993 | DEVICE FOR MITIGATING OR PREVENTING PARAVALVULAR LEAKS - One aspect of the present disclosure relates to a device for preventing or mitigating paravalvular leakage associated with a valve replacement procedure. The device can include a first ring, a second ring axially spaced apart from the first ring, at least one pad section extending between the first and second rings, and a plurality of centering wires attached to at least one of the first and second rings. | 06-05-2014 |
20140155994 | TAVR Ventricular Catheter - A catheter for positioning a valve during a transcatheter aortic valve replacement is formed from a resilient hollow body conformable to a guide wire when a guide wire is passed in through an upper opening in the hollow body and through the hollow body. When the guide wire is retracted, the catheter deploys to form a substantially straight upper shaft portion that extends downwardly from the upper opening and a distal ring perpendicular to the upper shaft portion. The distal ring approximates the size and shape of the patient's aortic valve annulus. A lower loop connects the upper shaft portion of the catheter to the distal ring. An outer surface of the distal ring is radiopaque, and the distal ring comprises openings for dispersing radio opaque medium used in imaging of the patient's aortic valve annulus. The deployed catheter is retracted until it snugly contacts the aortic valve annulus. The distal ring will be viewed as a straight line when the x-ray C-arm is properly aligned with the aortic valve annulus. | 06-05-2014 |
20140163668 | METHODS AND SYSTEMS FOR DELIVERING PROSTHESES USING RAIL TECHNIQUES - Exemplary embodiments provide methods and systems for delivering a prosthesis to a target location in a lumenal system of a patient. At least one tether is secured proximate the target location to serve as a rail, and a prosthesis is advanced along the rail to the target location and secured in place. Exemplary methods and systems provide for repair of the mitral and tricuspid valves, as well as abdominal aortic aneurysms, stomach valves, fallopian tubes and the pulmonary system, among others. Also disclosed are various prostheses suitable for use with the disclosed methods and systems. | 06-12-2014 |
20140163669 | DEVICES AND METHODS FOR THE REPLACEMENT OF THE FUNCTIONING OF HEART VALVES - A valve device is provided for implantation at the location of a natural heart valve, for replacing the functioning of the natural heart valve. The valve device includes a holding structure and a plurality of leaflets that open and close as the heart beats and pressure changes. The valve device holding structure may comprise a substantially ring-shaped first section, or ventricular ring, and a substantially ring-shaped second section, or atrial ring, connected together by a connector. The valve device holding structure, which may include all parts besides the leaflets themselves, may be formed from a wire or tube made of a suitable flexible material that allows the valve device to be substantially straightened to a low profile in a constrained delivery condition and that allows the valve device to self-expand to its ring-shaped expanded profile when unconstrained during implantation. | 06-12-2014 |
20140163670 | PROSTHETIC HEART VALVE DELIVERY SYSTEM AND METHOD - A method for delivering a self-expanding prosthetic heart valve comprises positioning the prosthetic heart valve in an annulus of a native heart valve while mounted in a radially compressed state in a delivery cylinder, the delivery cylinder coupled to a distal end portion of the torque shaft, and rotating a torque shaft coupled to the delivery cylinder. Rotating the torque shaft retracts the delivery cylinder, thereby exposing the prosthetic heart valve, allowing the prosthetic heart valve to self-expand in the native valve annulus. In some embodiments, the torque shaft is rotated by a motor disposed in a handle at a proximal end of the delivery device. | 06-12-2014 |
20140172075 | Transcatheter Prosthetic Heart Valve Delivery System and Method with Controlled Expansion of Prosthetic Heart Valve - A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal end, an intermediate portion, and a first coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve via a first tether. A sheath assembly defines a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The first coupling structure is configured to be manipulated in a first direction to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve. | 06-19-2014 |
20140172076 | Delivery Device For Medical Implant And Medical Procedure - A catheter ( | 06-19-2014 |
20140188215 | METHOD AND APPARATUS FOR CATHETER-BASED ANNULOPLASTY USING LOCAL PLICATIONS - The present invention relates to a minimally invasive method of performing annuloplasty. According to one aspect of the present invention, a method for performing annuloplasty includes accessing a left ventricle of a heart to provide a discrete plication element to the left ventricle, and engaging the plication element to tissue near a mitral valve of the heart. Engaging the plication element includes causing the plication element to gather a portion of the tissue to create a plication. In one embodiment, accessing the left ventricle of the heart to provide the plication element includes accessing the left ventricle of the heart using a catheter arrangement. | 07-03-2014 |
20140188216 | EXPANDABLE ILIAC SHEATH AND METHOD OF USE - Disclosed is an expandable transluminal sheath, for introduction into the body while in a first, small cross-sectional area configuration, and subsequent expansion of at least a part of the distal end of the sheath to a second, enlarged cross-sectional configuration. The sheath is configured for use in the vascular system and has utility in the introduction and removal of implant delivery catheters. The access route is through the femoral arteries and the iliac arteries into the aorta. The distal end of the sheath is maintained in the first, low cross-sectional configuration during advancement to the arteries into the aorta. The distal end of the sheath is subsequently expanded using a radial dilatation device, which is removed prior to the introduction of implant delivery catheters. | 07-03-2014 |
20140188217 | PROSTHETIC VASCULAR CONDUIT AND ASSEMBLY METHOD - A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve. | 07-03-2014 |
20140194975 | Method of Treating Paravalvular Leakage After Prosthetic Valve Implantation - A method for treating paravalvular leakage at a location of a stented prosthetic valve includes the steps of delivering a clip to a location adjacent chordae tendinae of a native valve, and deploying the clip such that the clip captures at least some of the chordae tendinae of the native valve, thereby increasing tension in the captured chordae tendinae. The clip is delivered to the location in a collapsed stated and is released from a sheath convert to an undeflected or relaxed state. After the clip is released from the sheath, the clip is rotated to capture the chordae tendinae. The clip is then released from the delivery system and the delivery system is retracted. | 07-10-2014 |
20140194976 | DEVICES AND METHODS FOR HEART VALVE REPAIR - Devices and methods provide enhanced treatment of a cardiac valve annulus. Methods generally involve contacting an anchor delivery device with the valve annulus and releasing a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus. Anchors, which in some embodiments are super-elastic or shape memory self-securing anchors, are then drawn together to tighten the annulus. Devices generally include an elongate catheter having a housing at or near the distal end for releasably housing a plurality of coupled anchors. The housing may be flexible, may conform to a valve annulus, and in some embodiments may be coupled with an expandable member to enhance contact of the housing with annular tissue. In one embodiment, self-securing anchors lie approximately flat within the delivery device housing, allowing anchors with relatively large deployed shapes to be housed in and deployed from a relatively narrow delivery device. | 07-10-2014 |
20140194977 | METHODS AND APPARATUSES FOR DEPLOYING MINIMALLY-INVASIVE HEART VALVES - Methods and systems for delivering and deploying a prosthetic heart valve include a deployment mechanism coupled to the prosthetic heart valve, the deployment mechanism comprising a longitudinal shaft that when rotated in a first direction, expands the prosthetic heart valve from a contracted state to an expanded state, and optionally, when rotated in a second direction opposite the first direction, re-contracts the prosthetic valve from the expanded state. Embodiments of the deployment mechanism comprise a pinion gear that engages a gear track on the prosthetic heart valve. | 07-10-2014 |
20140200657 | Mitral Spacer - A heart valve implant may include a shaft and an anchor configured to be coupled to an end of the shaft. A spacer may be coupled to a portion of the shaft and comprise a plurality of individual segments including a first and at least a second individual segment. The first segment may be coupled to the shaft. The second segment may be coupled to at least a portion of an exterior surface of the first segment and may have at least one cross-section dimension which is greater than an internal cross-sectional dimension of a delivery lumen. Additional segments may be coupled to an inner, adjacent segment. The segments may include a collapsible body portion to facilitate percutaneously delivery through a lumen. The segments may define an outer surface of the spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position. | 07-17-2014 |
20140200658 | Method and Apparatus for Percutaneous Aortic Valve Replacement - A catheter adapted for placement in the ascending aorta comprises a central catheter mechanism and a balloon structure or other occluding structure at its distal end. The catheter may be placed over the aortic arch such that the occluding structure is placed in the ascending aorta just above the Sinus of Valsalva and coronary ostia. Once in place, the occluding structure is inflated to control blood flow through the aorta during aortic valve ablation and replacement protocols. | 07-17-2014 |
20140207230 | Implant Delivery and Deployment System and Method - An implant delivery system comprising a catheter including at least one lumen, an implant configured to be received in the lumen, and a latching mechanism configured to be received in the implant. The latching mechanism may be configured to releasably couple the implant to a delivery wire and to transmit a torque through the delivery wire to cause at least a portion of the implant to rotate. The an implant may comprise a shaft, a spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position, a garage configured to couple the spacer to a first end region of the shaft, and at least one anchor mechanism. The garage may define a cavity configured to receive the latching mechanism and to increase rotational and translational stability of the latching mechanism. | 07-24-2014 |
20140207231 | ANCHORING OF PROSTHETIC VALVE SUPPORTS - Apparatus is provided, including: (1) a delivery tube, transluminally advanceable to the heart of the subject; (2) a prosthetic valve support, configured to support a prosthetic valve at a native valve of the heart, and including an upstream support portion, the upstream support portion: (A) having a working configuration in which it is generally annular and (B) having a delivery configuration in which it defines a channel, and is configured to be disposed within the delivery tube; (3) a tissue anchor, slidable through the channel; and (4) an anchor driver. The anchor driver is slidable within the delivery tube and the channel, and configured to anchor the upstream support portion to tissue of the heart by driving the tissue anchor through the upstream support portion and into the tissue, while at least part of the upstream support portion is disposed within the delivery tube. | 07-24-2014 |
20140214151 | DELIVERY DEVICE DISTAL SHEATH CONNECTOR - A connector for coupling a distal sheath to an inner shaft of a medical delivery device includes a wedge defining a lumen for accepting the inner shaft of the medical delivery device and a cylindrical ring sized to mate with the wedge. The wedge may be welded or otherwise fixed to the inner shaft. The wedge and the ring are configured to be pressed together and lock a portion of the distal sheath therebetween. | 07-31-2014 |
20140214152 | METHOD AND DEVICE FOR HEART VALVE REPAIR - A repair device for repairing a heart valve leaflet in a patient includes a hollow body with a capture tool and a tissue puncture element at the distal end thereof. The capture tool may be used to capture and stabilize the heart valve leaflet tissue. The tissue puncture element may puncture the leaflet tissue and deploy at least one anchor having a length of suture attached thereto. By tensioning the suture, the leaflet tissue may become plicated. The tensioned suture may then be cinched to maintain the plication. | 07-31-2014 |
20140214153 | Methods of implanting an endoprosthesis - A catheter is disclosed for the transvascular implantation of prosthetic heart valves, e.g., including self-expanding anchorage supports, to reduce the risk to the patient during the implantation. Accordingly, a prosthetic heart valve comprising anchorage supports is temporarily housed in a folded form in a cartridge-type unit during the implantation. The cartridge-type unit can be fixed on the proximal end of a guide system, which comprises a flexible region that can be guided through the aorta. Actuating elements run through the interior of the hollow guide system, permitting sections of the cartridge-type unit to be displaced radially about their longitudinal axis and/or laterally in a proximal direction, thus allowing individual sections of the anchorage support and the associated prosthetic heart valve to be sequentially released. | 07-31-2014 |
20140214154 | Methods for delivering a self-expanding valve - Methods for delivering a prosthetic heart valve include advancing a delivery catheter containing the prosthetic heart valve to a deployment location at a native heart valve, advancing an inner core movably coupled to a restraining sheath of the delivery catheter to expose a first end of the prosthetic heart valve, and advancing the inner core and the restraining sheath to expose a second end of the prosthetic heart valve. The delivery catheter can include a distal flange located at a distal end of an outer core of the catheter body, configured to restrict distal longitudinal displacement of the prosthetic heart valve, and a retaining structure located proximally from the distal flange along the outer core of the catheter body, configured to restrict proximal longitudinal displacement of the prosthetic heart valve. | 07-31-2014 |
20140214155 | Methods For Deployment Of Medical Devices - Methods for delivering a medical device loaded onto a catheter include positioning a first tube relative to a second concentric tube such that sheathing material having a first end affixed to the first tube and a second end affixed to the second tube forms an inner layer and an outer layer having at least one inversion point, such that no portion of the first tube is between any portion of the inner and outer layers of the sheathing material. Upon positioning the catheter at a desired target site, the first tube can be moved relative to the second tube so that the inversion point moves to expose the medical device, thereby permitting expansion of the medical device at the target site. | 07-31-2014 |
20140214156 | APPARATUS AND METHOD FOR REPLACING A DISEASED CARDIAC VALVE - An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration. | 07-31-2014 |
20140214157 | TRANSCATHETER VALVE PROSTHESIS - A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove. | 07-31-2014 |
20140222135 | PROSTHETIC HEART VALVES, SCAFFOLDING STRUCTURES, AND SYSTEMS AND METHODS FOR IMPLANTATION OF SAME - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. | 08-07-2014 |
20140222136 | PROSTHETIC VALVE FOR REPLACING MITRAL VALVE - Embodiments of prosthetic valves for implantation within a native mitral valve are provided. One embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve member. In some cases, the prosthetic valves also include ventricular anchors and/or an atrial portion coupled to and disposed outside of the main body. Methods, devices, and systems for delivering such prosthetic valves to the native mitral valve and implanting them therein are also provided. | 08-07-2014 |
20140222137 | TOOL FOR ACTUATING AN ADJUSTING MECHANISM - Apparatus is provided, including a tissue-adjusting member selected from the group consisting of: one or more artificial chordae tendineae and at least a portion of an annuloplasty ring structure. The tissue-adjusting member includes an adjusting mechanism that is configured to adjust a tension of the tissue-adjusting member. The adjusting mechanism includes a locking mechanism configured to restrict adjusting of the tissue-adjusting member by the adjusting mechanism. An elongate member is configured to maintain the locking mechanism in an unlocked state during adjusting of the tension of the tissue-adjusting member by the adjusting mechanism, and facilitate locking of the adjusting mechanism by the locking mechanism. A tool is configured to facilitate actuation of the adjusting mechanism to adjust the tension of the tissue-adjusting mechanism. The elongate member and the tool are slidably coupled with respect to each other. Other applications are also described. | 08-07-2014 |
20140222138 | Devices, Systems, and Methods for Reshaping a Heart Valve Annulus, Including the Use of Magnetic Tools - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 08-07-2014 |
20140222139 | EXPANDABLE INTRODUCER SHEATH - An introducer sheath has a radially unexpanded and a radially expanded configuration, where the sheath locally expands from the unexpanded configuration to the expanded configuration when a device is advanced through a lumen thereof, and locally contracts back to the unexpanded configuration after the device advances past that location. Embodiments of the introducer sheath include an outer tubular layer comprising a longitudinal cut therethrough, and an inner tubular layer comprising at least one pleat extending through the longitudinal cut to an outside surface of the outer tubular layer. Embodiments of the inner tubular layer are adhered to an inner surface of the outer tubular layer, with the pleat not adhered to an outer surface of the outer tubular layer. | 08-07-2014 |
20140236287 | Transcatheter Valve Prosthesis and a Concurrently Delivered Sealing Component - A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis. | 08-21-2014 |
20140243953 | Medical Device Delivery Systems and Methods of Use Thereof - A delivery system for delivering a medical device through a vasculature can include a capsule for housing the medical device during delivery and a marker band rotatably fixed to the capsule. The marker band can include a band portion and a single indicator protruding from the band portion. The indicator can allow the rotational orientation of the marker band to be determined while the medical device is in the vasculature, the rotational orientation being around a central axis of the vasculature. A delivery system for delivering a medical device through a vasculature includes a capsule for housing the medical device during delivery and a marker band attached to a proximal end of the capsule. The marker band can include a base portion and a protrusion that can be configured to extend from the base portion towards a distal end of the capsule. Related methods are also described. | 08-28-2014 |
20140243954 | TRANSCATHETER MITRAL VALVE PROSTHESIS - An intraluminal device replaces the mitral valve in the human heart without tissue insult or injury via catheter-based deployment and securement. By controlling radial force, a one-piece device in a substantially hyperboloid configuration is emplaced using a least one of a biological adhesive and a porous layer encapsulating the device, for example, ePTFE, to manage the potential for migration. Systems for emplacement are likewise disclosed. | 08-28-2014 |
20140243955 | METHOD OF CONTROLLED RELEASE OF A PERCUTANEOUS REPLACEMENT HEART VALVE - A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent. | 08-28-2014 |
20140243956 | METHOD OF CONTROLLED RELEASE AND SUBSEQUENT DEPLOYMENT OF A PERCUTANEOUS REPLACEMENT HEART VALVE - A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent. | 08-28-2014 |
20140243957 | STAGED DEPLOYMENT DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device for a collapsible heart valve includes an operating handle, including a frame defining a movement space therein, a carriage assembly moveable within the movement space, and a first resheathing lock having a locked position and an unlocked position. The delivery device further includes a catheter assembly, including a first shaft around which a valve-receiving compartment is defined, the first shaft being fixedly connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly. The distal sheath is moveable between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve. With the resheathing lock in the locked position, the distal sheath is unable to move to the open condition to fully deploy the valve. | 08-28-2014 |
20140243958 | METHOD FOR TREATING AN AORTIC VALVE - A method for replacing a native heart valve with a prosthetic heart valve comprises moving a first portion of a prosthetic heart valve towards a second portion of the prosthetic heart valve along a plurality of guide wires, and lock the first portion to the second portion in a final, radially expanded configuration. The prosthetic heart valve is radially contractible and expandable, and in some embodiments, is self-expanding. Embodiments of the method are minimally invasive. | 08-28-2014 |
20140243959 | Inversion Delivery Device and Method For A Prosthesis - A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations. | 08-28-2014 |
20140243960 | Inversion Delivery Device and Method For A Prosthesis - A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations. | 08-28-2014 |
20140243961 | Inversion Delivery Device and Method For A Prosthesis - A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations. | 08-28-2014 |
20140243962 | Inversion Delivery Device and Method For A Prosthesis - A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations. | 08-28-2014 |
20140243963 | ANNULOPLASTY RING DELIVERY CATHETHERS - Apparatus is provided, including a first catheter having a distal end portion transluminally advanceable to a vicinity of an anatomical site, a second catheter having a distal end portion advanceable through a first lumen and out of the first lumen, and a longitudinal implant, advanceable through the second lumen and out of the second lumen. The first and second catheters are assembled to facilitate sliding of the first and second catheters and of the implant, to configure them to assume a multi-bend formation having first and second bends separating first, second, and third domains. The first domain includes parts of the first and second catheters. The second domain includes the distal end portion of the second catheter, part of the implant, and none of the first catheter. The third domain includes part of the implant and none of the first nor second catheters. Other embodiments are also described. | 08-28-2014 |
20140249621 | Transapical Mitral Valve Replacement - A prosthetic heart valve includes a collapsible and expandable stent having an outflow end and an inflow end, a plurality of commissure features attached to the stent, a plurality of anchoring features disposed on legs of the stent, the plurality of anchoring features being coupleable to a delivery device for repositioning, and a valve assembly disposed within the stent. The anchoring features may be configured to attach to heart tissue to help secure the prosthetic heart valve in an operating position. | 09-04-2014 |
20140249622 | Implant Intended for Positioning in a Blood Flow Passage and Associated Treatment Device - The implant ( | 09-04-2014 |
20140257466 | TRANSCATHETER VALVE REPLACEMENT - A prosthetic heart valve having an inflow end and an outflow end includes a collapsible and expandable stent. A collapsible and expandable valve assembly is disposed within the stent and includes a plurality of leaflets. A collapsible and expandable frame formed of braided wires has a body portion and a lumen extending through the body portion for receiving the stent and the valve assembly. The frame may include features for holding the prosthetic heart valve in place in a patient. | 09-11-2014 |
20140257467 | PROSTHETIC VALVE WITH ANTI-PIVOTING MECHANISM - A prosthetic valve for implanting in a patient's native valve has a self-expanding frame that comprises a first end, a second end opposite the first end, an anterior portion, and a posterior portion. The self-expanding frame has an expanded configuration adapted to engage tissue at a treatment site, and a collapsed configuration adapted to be delivered to the treatment site. The expandable frame also comprises a self-expanding atrial skirt near the second end, a self-expanding ventricular skirt near the first end, a self-expanding annular region disposed between first and second ends, a first self-expanding anterior tab disposed on the anterior portion, and a self-expanding foot coupled to the posterior portion and extending radially outward. The foot has an outer surface for engaging the tissue thereby facilitating anchoring of the prosthetic valve and minimizing or preventing rotation of the prosthetic valve. | 09-11-2014 |
20140257468 | Valve Holder With Leaflet Protection - An implantation device for a prosthetic heart valve includes a valve holder for maintaining the prosthetic heart valve in a closed configuration and at least one protective sheet coupled to the valve holder, the at least one protective sheet being configured to cover a leaflet of the heart valve during implantation. | 09-11-2014 |
20140257469 | METHOD OF CONTROLLED RELEASE AND SUBSEQUENT DEPLOYMENT OF A PERCUTANEOUS REPLACEMENT HEART VALVE - A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent. | 09-11-2014 |
20140257470 | METHOD AND APPARATUS FOR RESECTING AND REPLACING AN AORTIC VALVE - Apparatus for resecting a diseased heart valve, the apparatus comprising: a body portion; a first handle and a second handle; a cutting blade; a set of retaining arms; a pass-off tool having a first attachment device configured to selectively engage the first handle attached to the body portion so as to allow placement of the second handle of the body portion adjacent to the diseased heart valve, and a controller tool having a second attachment device at the distal end thereof, the second attachment device configured to selectively engage the second handle attached to the body portion so as to allow positioning of the body portion adjacent to the diseased heart valve, a cutting blade actuator configured to cause the cutting blade to selectively rotate, and a retaining arm actuator configured to selectively position the set of retaining arms from the contracted state to the expanded state. | 09-11-2014 |
20140257471 | Controlled Tip Release Stent Graft Delivery System and Method - An apparatus and method of deploying a stent graft having a proximal anchor stent ring includes restraining proximal apexes of the proximal anchor stent ring between a spindle body of a spindle and a control release sleeve of a tapered tip. The control release sleeve is advanced relative to the spindle to release a first proximal apex through an opening in the control release sleeve while the remaining proximal apexes remain restrained by the control release sleeve. The control release sleeve is further advanced relative to the spindle to release the remaining proximal apexes from the control release sleeve. In another example, a stent capture fitting has variable length stent capture fitting arms. As the stent capture fitting is retracted, the proximal apexes of the proximal anchor stent ring are sequentially exposed from and released by the variable length stent capture fitting arms. By using the control release sleeve or the stent capture fitting, controlled sequential release of the proximal apexes is achieved. | 09-11-2014 |
20140277403 | Devices and Methods for Preparing A Transcatheter Heart Valve System - Devices and methods for preparing a transcatheter heart valve system. The device includes a housing, sealing apparatuses and a port. The housing forms a chamber sized to receive a prosthetic valve and a portion of a delivery device. During use, the prosthesis is seated in the chamber, and the sealing apparatuses operated to seal the chamber about the delivery device. Air bubbles in a liquid delivered through the delivery device and to the chamber are removed from the system via the port, thereby flushing the system. Further, the device is manipulated to permit loading of the prosthesis into the delivery device in an air bubble-free environment. | 09-18-2014 |
20140277404 | TRANS-APICAL IMPLANT SYSTEMS, IMPLANTS AND METHODS - A trans-apical implant includes a spacer defining spacer cavity configured to be expanded from a retracted position, a shaft extending from the spacer, the shaft defining an inflation lumen fluidly coupled to the spacer cavity and configured to be fluidly coupled to an expansion medium source, and a spacer valve assembly disposed within at least one of the spacer or shaft, the spacer valve assembly configured to allow selectively allow an expansion medium to flow into the spacer cavity to be selectively expand the spacer from a retracted position to an expanded position. | 09-18-2014 |
20140277405 | MITRAL VALVE SPACER AND SYSTEM AND METHOD FOR IMPLANTING THE SAME - A trans-femoral implant includes an anchor assembly and a balloon assembly configured to be separately delivered to an implant site within a heart. Once delivered, the anchor assembly and balloon assembly may be coupled to form an implant within the heart. The balloon anchor may include a fluid inflatable balloon that may be selectively filled via a balloon filling valve. The balloon assembly may further include a latching mechanism that may couple with a distal end of the anchor assembly, such that the length of the implant may be adjusted within the heart. | 09-18-2014 |
20140277406 | Method and Apparatus for Mitral Valve Annuloplasty - A method for mitral valve annuloplasty includes inserting a catheter apparatus across an aortic valve, the catheter apparatus including a tissue penetration member having a distal fixation end. The method further includes penetrating an aortomitral continuity and tissue of a fibrous trigone with the catheter apparatus from a left ventricular outflow tract beneath the aortic valve, and advancing the catheter apparatus along annular tissue of a mitral valve annulus. The distal fixation end is deployed to engage the annular tissue, the tissue penetration member is retracted within the catheter apparatus to compress the annular tissue a desired distance for reduction of the annular tissue, and the retracted tissue penetration member is secured to anchor the annular tissue reduction. | 09-18-2014 |
20140277407 | SIMULATED ENVIRONMENT FOR TRANSCATHETER HEART VALVE REPAIR - An apparatus for applying liquid pressure to resected tissue may include a fixture, a papillary assembly coupled to the fixture and having first and second spaced apart papillary attachment elements, and a resected mitral valve attached to the fixture. The fixture may have a first chamber, a second chamber, and an internal panel extending between the first and second chambers. The resected mitral valve may be attached to the internal panel and may have a posterior leaflet, an anterior leaflet, and tendinae chordae. The tendinae chordae may each be attached at a first end to the posterior leaflet or the anterior leaflet and at a second end to one of the papillary attachment elements. A first group of the tendinae chordae may be attached to the first papillary attachment element, and a second group of the tendinae chordae may be attached to the second papillary attachment element. | 09-18-2014 |
20140277408 | Prosthetic Heart Valve System - In at least one embodiment, a prosthetic valve assembly comprises a pouch connecting two valves to one another. The valve assembly is delivered by a catheter system. In some embodiments, the valve assembly includes a valve for replacing a mitral valve and a valve for replacing an aortic valve. The valve assembly may optionally include an adhesive layer on the outer surface. | 09-18-2014 |
20140277409 | TRANSCATHETER VALVE PROSTHESIS - A system for implanting a heart valve includes a radially self-expandable tubular body having a preformed groove disposed at an outer surface of the tubular body, and a valve disposed within the tubular body. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward. A trapping member is configured to be disposed within the preformed groove on the outer surface of the tubular body and form at least a partial loop around the tubular body. The circumferential opening of the preformed groove is relatively larger when an outflow end of the tubular body has been deployed from a catheter and an inflow end of the tubular body is disposed within the catheter, and the circumferential opening of the preformed groove is relatively smaller when both the outflow end and the inflow end are fully deployed from the catheter. | 09-18-2014 |
20140277410 | TRANSCATHETER VALVE PROSTHESIS - A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end. The preformed groove extends at least partially around the tubular body and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and is attached to the tubular body, and an elongate outer member is configured to form a loop encircling the preformed groove so as to guide portions of native valve leaflets and/or chords into the preformed groove. The outflow end of the tubular body includes a frustoconical shape that slopes radially outward from the preformed groove toward the outflow end when the outflow end but not the inflow end has been released from a delivery catheter. | 09-18-2014 |
20140277411 | TRANSCATHETER VALVE PROSTHESIS - A method for implanting a heart valve includes advancing an elongate outer member from a first delivery catheter to form a loop around native valve leaflets and/or chords of a native valve without substantially occluding the native valve. The method further includes partially deploying from a second delivery catheter a radially self-expandable tubular body having a valve disposed within a lumen of the tubular body, and a preformed groove disposed at an outer surface of the tubular body. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. When the tubular body is partially deployed, the native valve is substantially occluded. Additionally, the method includes moving the loop into the preformed groove after partially deploying the tubular body. The native valve is no longer substantially occluded after fully deploying the tubular body from the second delivery catheter. | 09-18-2014 |
20140277412 | TRANSCATHETER VALVE PROSTHESIS - A system for implanting a heart valve that includes a radially self-expandable tubular body having an inflow end and an outflow end, and a valve disposed within and attached to the tubular body. A first end of a projection is located at a side surface of the tubular body, and a second free end of the projection defines a groove between the projection and the tubular body. The groove has an opening between the tubular body and the second free end of the projection. Additionally, an elongate outer member is configured to move into the groove and to move heart tissue into the groove, such that the heart tissue is disposed between the tubular body and the projection. | 09-18-2014 |
20140277413 | SYSTEM AND METHOD FOR SEALING PERCUTANEOUS VALVE - A percutaneous valve device and system are provided, which improve sealing between the anchor and native anatomy. The anchor includes a space-occupying material, such as a hydrogel, on an external surface that swells when exposed to an aqueous environment, filling gaps between the anchor and the native anatomy, and thereby serves as a valve seal. | 09-18-2014 |
20140277414 | PERCUTANEOUS HEART VALVE DELIVERY SYSTEMS - Embodiments described herein address the need for improved catheter devices for delivery, repositioning and/or percutaneous retrieval of the percutaneously implanted heart valves. One embodiment employs a plurality of spring-loaded arms releasably engaged with a stent frame for controlling expansion for valve deployment. Another embodiment employs a plurality of filaments passing through a distal end of a pusher sleeve and apertures in a self-expandable stent frame to control its state of deployment. With additional features, lateral positioning of the stent frame may also be controlled. Yet another embodiment includes plurality of outwardly biased arms held to complimentary stent frame features by overlying sheath segments. Still another embodiment integrates a visualization system in the subject delivery system. Variations on hardware and methods associated with the use of these embodiments are contemplated in addition to those shown and described. | 09-18-2014 |
20140277415 | METHOD OF DEPLOYING A PERCUTANEOUS REPLACEMENT HEART VALVE - A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent. | 09-18-2014 |
20140288639 | Low-Profile Prosthetic Valve Structure - A prosthetic valve assembly that includes a stent, a tissue sleeve and an anchoring mechanism. By loading the three components of the valve assembly into a delivery catheter in a series formation, such that no two components are located within each other, the size of the delivery catheter can be reduced. | 09-25-2014 |
20140288640 | SYSTEMS AND METHODS FOR IMPROVED VESSEL ACCESS CLOSURE - Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis. | 09-25-2014 |
20140296969 | Anterior Leaflet Clip Device for Prosthetic Mitral Valve - This invention relates to a pre-configured compressible transcatheter prosthetic cardiovascular valve having an improved anterior leaflet clip device. The invention also relates to methods for deploying such a valve for treatment of a patient in need thereof. | 10-02-2014 |
20140296970 | Positioning Tool for Transcatheter Valve Delivery - This invention relates to a positioning device for delivery of a transcatheter prosthetic heart valve that comprises a ratchet rod with reference scale for accurate positioning a valve during deployment, and methods of use thereof. | 10-02-2014 |
20140296971 | Alignment Device for Asymmetric Transcatheter Valve - This invention relates to relates to a alignment device for providing the correct valve alignment during deployment of an asymmetrical transcatheter valve while it is being deployed in a patient in need thereof, and methods of use thereof. | 10-02-2014 |
20140296972 | Deployment Compensator for Transcatheter Valve Delivery - This invention relates to a deployment compensator for reducing the expelling force of a compressed transcatheter valve while it is being deployed in a patient in need thereof, and methods of use thereof. | 10-02-2014 |
20140296973 | METHODS AND SYSTEMS FOR CARDIAC VALVE DELIVERY - The present invention provides systems and methods for the repair, removal, and/or replacement of heart valves. The methods comprise introducing a delivery system into the heart, wherein a prosthesis is disposed on the delivery member attached to the delivery system, advancing the prosthesis to the target site, and disengaging the prosthesis from the delivery member at the target site for implantation. The present invention also provides implant systems for delivering a prosthesis to a target site in or near the heart. In one embodiment of the present invention, the implant system comprises a delivery system, an access system, and a prosthesis. | 10-02-2014 |
20140296974 | SYSTEM AND METHOD FOR ASSISTING THE POSITIONING OF MEDICAL INSTRUMENTS - The present invention relates to a device, system and method for assisting the positioning of medical instruments. The system comprises a hollow tubular member such as a sheath or sleeve comprising a rotational indicator element. The system further comprises an elongated rod having a blade on its distal end and comprising a rotational indicator element (aligned with the blade orientation) and a stopper close to its proximal end. | 10-02-2014 |
20140303718 | Retrieval and repositioning system for prosthetic heart valve - This invention relates to the design and function of a retrieval device for a prosthetic heart valve for re-positioning or removal of a previously implanted valve prosthesis from a beating heart without extracorporeal circulation using a transcatheter retrieval system. | 10-09-2014 |
20140303719 | PERCUTANEOUSLY IMPLANTABLE ARTIFICIAL HEART VALVE SYSTEM AND ASSOCIATED METHODS AND DEVICES - Expandable prosthetic valve devices for repair or replacement of a native valve in a heart of a patient and associated, systems and methods are disclosed herein. An expandable prosthetic valve device configured in accordance with a particular embodiment of the present technology can include a radially-expandable support having an expandable outer wall and a lumen defined by the outer wall. The device can also include a valve in the lumen and coupled to the support and a self-expanding retainer coupled to the outer wall. The retainer can have a structural braid configured to form a first annular flange on the outer wall of the support, and an occlusive braid configured to reduce blood flow through the retainer. | 10-09-2014 |
20140303720 | TISSUE PLICATION DEVICES AND METHODS FOR THEIR USE - A tissue plication device and method of using the same is described. The tissue plication device includes a helical fastener having a distal portion with a first pitch and a proximal portion with a second pitch that is smaller than the first pitch. The method includes introducing the distal tip of the helical fastener into the tissue and advancing the helical fastener to plicate the tissue. Another tissue plication device includes a helical fastener having a first configuration with a first pitch and a second configuration with a second pitch. The helical fastener in the first configuration is advanced into a tissue and then converted to the second configuration by applying a stimulus. | 10-09-2014 |
20140303721 | METHODS AND DEVICES FOR ACCESSING AND DELIVERING DEVICES TO A HEART - Described here are devices and systems for accessing and delivering devices to a heart. The left atrial appendage may be used as an access port to allow pericardial access to internal structures of the heart. Systems that may be used to provide access to the heart via the left atrial appendage may comprise a first access element with a first alignment member, a second access element with a second alignment member, a piercing element, and an exchange element. A piercing element may be advanced to pierce the wall of the left atrial appendage to form an access site therethrough. Optionally, an exchange element may be advanced to initiate a track between the inside and outside of the left atrial appendage, which may be used for device delivery. Some systems may further comprise a left atrial appendage stabilization device. | 10-09-2014 |
20140303722 | APPARATUS AND METHOD FOR IMPLANTING COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES - Apparatus for delivering a prosthetic heart valve into a patient by means that are less invasive than conventional open-chest, open-heart surgery. The prosthetic valve may be collapsed while in a delivery device. When the valve reaches the desired implant site in the patient, the valve can be released from the delivery device, which allows the valve to re-expand to the configuration in which it can function as a heart valve. For example, the delivery device may be constructed to facilitate delivery of the prosthetic valve into the patient via the apex of the patient's heart. | 10-09-2014 |
20140309727 | MITRAL HEART VALVE PROSTHESIS AND ASSOCIATED DELIVERY CATHETER - The invention relates to a mitral heart valve prosthesis and a delivery catheter to carry and deploy such a prosthesis. The invention allows to effectively treat a pathology related to moderate to severe mitral regurgitation. Such a prosthesis implantable by catheterism includes mainly a docking station and a leaflet cooperating with the docking station. The leaflet is advantageously arranged in a configuration close to a posterior leaflet of a native mitral valve of a patient. | 10-16-2014 |
20140309728 | TRANSAPICAL METHOD OF DELIVERING PROSTHETIC HEART VALVE - A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer sheath is passed over the guidewire and into the left ventricle. A prosthetic heart valve is advanced over the guidewire and through the introducer sheath using a delivery catheter. After positioning the prosthetic heart valve in the native aortic valve, the prosthetic heart valve is radially expanded in the aortic valve annulus for replacing the function of the native aortic valve. | 10-16-2014 |
20140309729 | Devices and Methods for Treating Valvular Regurgitation - A system for treating mitral valve regurgitation includes a tensioning device having a plurality of helical anchors and a tensioning filament. One embodiment of the invention includes a method for attaching a tensioning device to the annulus of a mitral valve in a trans-leaflet configuration, and applying a tension force to the tension filament in order to exert force vectors on the annulus, thereby reshaping the mitral valve annulus so that the coaption of the anterior and posterior leaflets of the mitral is improved during ventricular contraction. | 10-16-2014 |
20140309730 | Heart Valve Repair Device - A heart valve annulus repair device having a tissue engaging member and a plurality of anchors. The tissue engaging member includes a loop of wire. Each of the anchors has a pointy front end and a back end and a slot that runs in a front-to-back direction. The anchors are distributed about the loop of wire with the front ends of the plurality of anchors facing the heart valve annulus and with the loop of wire passing through the slots. The device further includes means for implanting the anchors into the heart valve annulus tissue so that the tissue engaging member becomes affixed to the heart valve annulus. | 10-16-2014 |
20140316517 | METHODS AND DEVICES FOR DELIVERY OF PROSTHETIC HEART VALVES AND OTHER PROSTHETICS - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described. | 10-23-2014 |
20140316518 | HANDLE MECHANISM AND FUNCTIONALITY FOR REPOSITIONING AND RETRIEVAL OF TRANSCATHETER HEART VALVES - Improved catheter devices for delivery, repositioning and/or percutaneous retrieval of percutaneously implanted heart valves are described, including a medical device handle that provides an array of features helpful in conducting a percutaneous heart valve implantation procedure while variously enabling radial expansion or contraction and/or lateral positioning control over the heart valve during the medical procedure. | 10-23-2014 |
20140316519 | CARDIAC VALVE WITH SHIELDS FOR TISSUE RETRACTION - A tissue retraction system for a bioprosthetic cardiac valve base configured for attachment to a separate leaflet set includes a plurality of retraction shields releasably attached to the valve base. The retraction shields are configured to restrain tissue within a surgical site. The retraction shields may be flexible and transparent. Shield extenders can be attached to the retraction shields and used to further secure the retraction shields to a device for providing tissue retraction during a surgical procedure. | 10-23-2014 |
20140324160 | LOW-PROFILE HEART VALVE AND DELIVERY SYSTEM - Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed. | 10-30-2014 |
20140324161 | RETRIEVAL AND REPOSITIONING SYSTEM FOR PROSTHETIC HEART VALVE - This invention relates to the design and function of a retrieval device for a prosthetic heart valve for re-positioning or removal of a previously implanted valve prosthesis from a beating heart without extracorporeal circulation using a transcatheter retrieval system. | 10-30-2014 |
20140324162 | STAGED DEPLOYMENT DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY - A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve. | 10-30-2014 |
20140330366 | SYSTEM AND METHOD FOR TRANSAORTIC DELIVERY OF A PROSTHETIC HEART VALVE - A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus via a transaortic approach. The system includes a balloon catheter for delivering a balloon-expandable prosthetic heart valve through an introducer from an approach from outside the patient, through a minimally-invasive opening in the chest cavity through an incision in the aorta, and into the aorta and aortic annulus. The balloon catheter includes a flexible, tapered tip just distal of the balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized. | 11-06-2014 |
20140330367 | PERSONALIZED AORTIC VALVE PROSTHESIS - A personalized prosthetic valve for implantation at a native valve treatment site includes a self-expanding mesh and a plurality of valve leaflets coupled to the mesh. The mesh may be delivered to the native valve in a collapsed configuration, and in an expanded configuration the mesh engages the native valve. The mesh in the expanded configuration is also personalized to match the treatment site, such that the outer mesh surface substantially matches the treatment site shape and size. The self-expanding mesh forms a central lumen configured to allow blood or other body fluids to pass therethrough. In the open configuration, blood passes through the prosthetic valve, and in the closed configuration, the plurality of leaflets are closer together and blood is prevented from flowing upstream through the prosthetic valve. | 11-06-2014 |
20140330368 | Valve Delivery Tool - A system includes a medical device for implanting in a valve of a subject, the implantable medical device having a self-expanding frame; and a holder configured to retain the frame of the implantable medical device in a constricted configuration and to control expansion of the frame. The holder has a controllably constrictable and expandable loop, wherein the loop is disposed about at least a portion of the self-expanding frame such that constriction or expansion of the first loop controls constriction or expansion of the frame. | 11-06-2014 |
20140336751 | Inflatable Transcatheter Intracardiac Devices and Methods for Treating Incompetent Atrioventricular Valves - Inflatable heart valve implants and methods utilizing those valves designed to reduce or eliminate the regurgitant jet associated with an incompetent atrioventricular valve. The heart valve implants, which are deployed via a transcatheter venous approach, comprise an inflatable balloon portion movably connected to an anchored guide shaft and movable from a distal position in the ventricle to a more proximal position between leaflets of a native atrioventricular valve. The range of movement of the inflatable valve body can be adjusted in situ after or before the guide shaft has been anchored to native heart tissue during surgery. | 11-13-2014 |
20140336752 | SYSTEM FOR DEPLOYING A DEVICE TO A DISTAL LOCATION ACROSS A DISEASED VESSEL - Configurations are described for assisting execution of a percutaneous procedure while protecting the vascular pathway to the operational theater. One embodiment is directed to a system for deploying a device to a distal location across a diseased vessel, comprising a sheath comprising an expandable distal portion comprising a porous wall defining a lumen therethrough, the distal portion having a collapsed configuration, wherein the sheath has a first cross sectional outer diameter and a first lumen inner diameter, and an expanded configuration, wherein the sheath has a second cross sectional outer diameter and a second lumen inner diameter; wherein in the collapsed configuration, the sheath is configured to be advanced across at least a portion of the diseased vessel to a position adjacent the distal location without substantial size interference between the first cross sectional outer diameter of the sheath and an inner diameter profile of a lumen of the vessel. | 11-13-2014 |
20140336753 | EXPANDABLE MEMBER FOR DEPLOYING A PROSTHETIC DEVICE - An apparatus and method for delivering a prosthetic device through the vasculature of a patient includes a radially expandable member coupled to the distal end of an elongate shaft. The expandable member has an open frame configuration and an outer mounting surface for mounting the prosthetic device in a collapsed state thereon. The expandable member expands radially outwards from a first configuration to a second configuration to expand a prosthetic device mounted thereon. | 11-13-2014 |
20140336754 | Multiple Component Prosthetic Heart Valve Assemblies and Methods for Delivering Them - Multiple component heart valves and apparatus and methods for implanting them are provided. The heart valve generally includes a first annular prosthesis and a second valve prosthesis. The first prosthesis includes an annular member compressible from a relaxed condition to a contracted condition to facilitate delivery into a biological annulus, the annular member being resiliently expandable towards the relaxed condition. The first prosthesis also includes guide rails extending therefrom. The second prosthesis includes an annular frame, valve elements, and receptacles for receiving respective guide rails therethrough when the second prosthesis is directed towards the first prosthesis. In addition, a valve holder may releasably carry the valve prosthesis that includes channels for receiving respective guide rails therethrough when the guide rails are received through the valve prosthesis. A delivery tool is also provided that includes an actuator for selectively compressing the annular member into the contracted condition. | 11-13-2014 |
20140343668 | ANNULOPLASTY RING WITH INTRA-RING ANCHORING - Apparatus is provided that includes an annuloplasty system for use on a subject. The system includes an annuloplasty ring, which includes a sleeve having a lumen, and at least one anchor, shaped so as to define a coupling head and a tissue coupling element, which tissue coupling element is shaped so as to define a longitudinal axis, and is configured to penetrate cardiac tissue of the subject in a direction parallel to the longitudinal axis. The system further includes an anchor deployment manipulator, configured to be removably positioned within the lumen of the sleeve, and, while so positioned, to deploy the tissue coupling element from a distal end of the deployment manipulator through a wall of the sleeve into the cardiac tissue in the direction parallel to the longitudinal axis of the tissue coupling element and parallel to a central longitudinal axis through the distal end of the deployment manipulator. | 11-20-2014 |
20140343669 | METHODS AND APPARATUS FOR DELIVERING A PROSTHETIC VALVE TO A BEATING HEART - A method for delivering a prosthetic valve to a patient's heart having a native valve with a plurality of valve leaflets includes providing a delivery device with a prosthetic valve, advancing the delivery device toward the native valve, and expanding a portion of the prosthetic valve to form a flanged region that is upstream of the valve leaflets. One or more tabs on the prosthetic valve are released so that they expand outward to a position that is transverse to the longitudinal axis of the prosthetic valve. The position of the prosthetic valve is adjusted relative to the valve leaflets and rapid pacing is applied to the patient's heart so that the valve leaflets move inward toward the prosthetic valve or the delivery device. The tabs are further released to allow the tabs to move into their final positions. | 11-20-2014 |
20140343670 | PROSTHETIC HEART VALVE DELIVERY APPARATUS - Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body. | 11-20-2014 |
20140350664 | Actuating Device for a Surgical - The present invention concerns an actuating device for actuating a mechanical adjustment element of surgical implant, said mechanical adjustment element allowing to modify the functional shape and/or the functional size of the surgical implant when actuated, said actuating device comprising transmission means linked with one end to the mechanical adjustment element and able to move the mechanical adjustment element when said transmission means are actuated, connecting means ( | 11-27-2014 |
20140350665 | COLLAPSIBLE AND RE-EXPANDABLE PROSTHETIC HEART VALVE CUFF DESIGNS AND COMPLEMENTARY TECHNOLOGICAL APPLICATIONS - A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the LVOT when the valve is implanted in a native aortic valve. The valve may include elements for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part of the cuff may be movable relative to the stent during implantation. | 11-27-2014 |
20140350666 | EXPANDABLE PROSTHETIC VALVE HAVING ANCHORING APPENDAGES - A heart valve prosthesis includes an expandable prosthetic valve including three valve leaflets coupled to an anchoring structure. The anchoring structure includes an annular member and a plurality of arms movably coupled to the annular member at one end. The free ends of the arms extend radially away from the prosthesis toward a valve annulus. The arms are configured to fit in a space defined between an open native valve leaflet and a wall of a valve sinus. The arms are sufficiently resilient such that they resist downward movement in response to pressure exerted on the prosthesis, facilitating anchorage and stabilization of the prosthesis at the implantation site. | 11-27-2014 |
20140350667 | COLLAPSIBLE AND RE-EXPANDABLE PROSTHETIC HEART VALVE CUFF DESIGNS AND COMPLEMENTARY TECHNOLOGICAL APPLICATIONS - A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the LVOT when the valve is implanted in a native aortic valve. The valve may include elements for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part of the cuff may be movable relative to the stent during implantation. | 11-27-2014 |
20140358222 | PLATFORMS FOR MITRAL VALVE REPLACEMENT - A mitral valve prosthesis is percutaneously and/or transapically deployed in at least two stages. In a first stage, a mitral annular ring platform adapted for percutaneous delivery is delivered to and anchored in the mitral valve annulus. In the second stage, a valved-stent mitral valve prosthetic device adapted for percutaneously delivery is delivered to the mitral valve annulus for mounting in the mitral annular ring platform. This approach provides a consistent platform for accepting valved-stent mitral valve prosthetic devices from different vendors to be used. | 12-04-2014 |
20140364939 | Delivery System with Inline Sheath - Systems and methods for delivering and implanting heart valves are disclosed. The delivery systems can include an integrated introducer. The integrated introducer can include a sheath having an inner diameter that is smaller than the outer diameter of a delivery capsule of the delivery system and an outer diameter that is approximately equal to the outer diameter of the delivery capsule. The integrated introducer can include a hub having a hemostatic seal. The hub can have a locking mechanism configured to fix the integrated introducer in place on the delivery system. | 12-11-2014 |
20140364940 | DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY - A clip for use during the loading of a prosthetic heart valve into a delivery device having an operating handle, a catheter assembly having a compartment for receiving the prosthetic heart valve, and an outer shaft joining the catheter assembly to the operating handle. The clip includes a first receiver coupleable to the operating handle of the delivery device and a second receiver coupleable to the outer shaft of the delivery device. The first and second receivers may be arranged orthogonally to one another so that in use the clip orients the catheter assembly substantially orthogonally to the operating handle. | 12-11-2014 |
20140364941 | MEDICAL DEVICE FOR MODIFICATION OF LEFT ATRIAL APPENDAGE AND RELATED SYSTEMS AND METHODS - Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a medical device coupled to a delivery catheter includes a fluid flow path that facilitates contrast fluid to pass through the delivery catheter and the medical device to a distal side thereof to provide imaging information as to the position of the medical device positioned in the opening, such as the left atrial appendage. In another embodiment, a medical device is coupled to a delivery catheter, the medical device including flaps adjacent a hub of the medical device that close-off a bore of the hub upon the catheter being detached from the medical device. | 12-11-2014 |
20140364942 | SYSTEM AND METHOD FOR LOADING A STENT INTO A MEDICAL DELIVERY SYSTEM - The present disclosure relates to a device ( | 12-11-2014 |
20140364943 | METHODS OF DELIVERY OF FLEXIBLE HEART VALVES - A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and/or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed. | 12-11-2014 |
20140371841 | Delivery System with Pacing Element - Medical device delivery assemblies are disclosed. The assembly may include a catheter-based delivery system. The assembly may include a pacing element to pace a patient's heart before, during, or after a procedure. The pacing element may be a detachable, implanting pacing element. The pacing element may be an implantable pacemaker and the implantable pacemaker may be disposed on a catheter-based delivery system. The assembly may include a prosthetic heart valve with one or more pacing elements on it. The pacing element may include a pacing strip or strips. These strips may be conductive or insulative. These strips may prevent, treat, or correct abnormal electrical communication in a heart. | 12-18-2014 |
20140371842 | CARDIAC IMPLANT WITH INTEGRATED SUTURE FASTENERS - A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures. | 12-18-2014 |
20140371843 | MITRAL VALVE SPACER AND SYSTEM AND METHOD FOR IMPLANTING THE SAME - A heart valve implant is disclosed herein. The heart valve implant comprises an inflatable valve body, a shaft, an anchor assembly and an inflation (injection) port. Also disclosed herein, are methods of trans-apically and trans-septally delivering a heart valve implant within a heart such that the valve body can be inflated in situ to partially or completely restrict blood flow through a heart valve in a closed position. The inflation (injection) port permits inflation of the valve body with an adjustable amount of an inflation fluid to attain a desired degree of inflation of the valve body when disposed within the heart valve. | 12-18-2014 |
20140371844 | TRANSCATHETER MITRAL VALVE AND DELIVERY SYSTEM - A prosthetic heart valve includes a collapsible and expandable stent, a collapsible and expandable valve assembly disposed within the stent, and one or more features coupled to the stent for at least partially anchoring the prosthetic heart valve within a native valve annulus of a patient. The anchoring features may include a body transitionable from an unfurled condition to a furled condition, the furled condition forming a flange for at least partially anchoring the heart valve, and/or a plurality of hooks transitionable from a deformed condition to a relaxed condition for at least partially anchoring the heart valve. A delivery device for the prosthetic heart valve may include a handle and a catheter member extending from the handle and having a first portion, a second portion, and a compartment for receiving the valve. The delivery device may provide for staged deployment of the valve. | 12-18-2014 |
20140371845 | Valve Suturing and Implantation Procedures - A prosthesis for implantation at a native semilunar valve includes a prosthetic distal valve, which includes a pliant material configured to collapse inwardly towards a longitudinal axis of the prosthesis during diastole, and to open outwardly during systole, and a distal fixation member configured to be positioned in a downstream artery of the subject. The apparatus also includes a proximal fixation member coupled to the distal fixation member, and configured to be positioned at least partially on a ventricular side of the native semilunar valve. The proximal fixation member is shaped so as to define a lattice that is shaped so as to define an intermediary portion that is coupled to the pliant material of the valve and diverges outwardly from the longitudinal axis, and a distal portion that is distal to the intermediary portion and diverges outwardly from the intermediary portion of the lattice. Other embodiments are also described. | 12-18-2014 |
20140371846 | MITRAL VALVE SPACER AND SYSTEM AND METHOD FOR IMPLANTING THE SAME - A heart valve implant is disclosed herein. The heart valve implant comprises an inflatable valve body, a shaft, an anchor assembly and an inflation (injection) port. Also disclosed herein, are methods of trans-apically and trans-septally delivering a heart valve implant within a heart such that the valve body can be inflated in situ to partially or completely restrict blood flow through a heart valve in a closed position. The inflation (injection) port permits inflation of the valve body with an adjustable amount of an inflation fluid to attain a desired degree of inflation of the valve body when disposed within the heart valve. | 12-18-2014 |
20140371847 | EXPANSION DEVICE AND METHOD FOR TREATING VASCULAR PASSAGEWAYS - Method for delivering an expandable member to a treatment location includes an elongate shaft and an expandable member coupled to a distal end of the elongate shaft. Embodiments of the expandable member are moveable between a collapsed configuration and an expanded configuration, and have an inner expandable member and a plurality of outer expandable members that at least partially surround the inner expandable member, and are suitable for delivering prosthetic heart valves and performing vavuloplasties. | 12-18-2014 |
20140371848 | TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY DEVICE WITH BIASED RELEASE FEATURES - A delivery system for percutaneously delivering and deploying a stented prosthetic heart valve. The delivery device includes a delivery sheath slidably disposed over an inner shaft, and a capture assembly. The capture assembly includes a spindle and a biasing member. The spindle is attached to the inner shaft and defines slot. The biasing member is disposed within the slot and self-transitions from a deflected condition to a normal condition. In a delivery state, the delivery sheath retains the prosthesis over the inner shaft and coupled to the spindle via the capture slot, including a portion of the prosthetic valve being engaged within the slot and the biasing member forced to the deflected condition. In a deployment state, the delivery sheath is proximally withdrawn and the biasing member self-transitions toward the normal condition to eject the prosthetic valve from the capture slot. | 12-18-2014 |
20140379074 | MITRAL VALVE DOCKING DEVICES, SYSTEMS AND METHODS - Various systems, devices and methods associated with the placement of a dock or anchor ( | 12-25-2014 |
20140379075 | IMPLANT DELIVERY SYSTEM AND METHOD - An implant delivery system may comprise a catheter including at least one lumen, a guide wire configured to be received in the lumen, and an implant. The guide wire may comprise a clamping mechanism disposed about a distal end of the guide wire. The clamping mechanism may include a first and at least a second jaw wherein at least one of the jaws is configured to pivot between a closed position wherein the jaws define at least one internal cavity between the jaws configured to receive at least a portion of the implant and an open position configured to release the implant. The implant may be configured to be received in the lumen and may comprise a driver configured to be releasably received in the cavity of the clamping mechanism. | 12-25-2014 |
20150012084 | Leaflet Valve - A device and method for improving flow through a native blood vessel valve, such as the aortic valve, are provided. The present invention allows a miniature valve to be implanted into affected leaflets percutaneously, obviating the need for coronary bypass surgery. The method includes the cutting of small holes, on the order of 4 mm, in the leaflets of a targeted valve, thereby allowing blood to flow through the newly formed holes. The holes are used as attachment sites for the miniature valves of the present invention. | 01-08-2015 |
20150012085 | Repositionable Heart Valve and Method - A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site. | 01-08-2015 |
20150018939 | Delivery System with Projections - Delivery systems for delivering medical devices and prosthetic heart valves in a patient's body are disclosed. The delivery system may include a catheter-based delivery system. The delivery system may include a tip, a capsule, an inner sheath, and a projection. The delivery system may include an outer sheath and a handle. The delivery system may be configured to be actuated via an actuator disposed on the handle. The projection may include an arm portion and a feeler portion. The feeler portion may include an indentation. The delivery system may be configured to correctly position a medical device or prosthetic heart valve. | 01-15-2015 |
20150018940 | HELICAL COIL MITRAL VALVE ANNULOPLASTY SYSTEMS AND METHODS - Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus. | 01-15-2015 |
20150018941 | METHODS AND APPARATUS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN - An implantable device is provided for controlling shape and/or size of an anatomical structure or lumen. The implantable device has an adjustable member configured to adjust the dimensions of the implantable device. The implantable device is housed in a catheter and insertable from a minimally invasive surgical entry. An adjustment tool actuates the adjustable member and provide for adjustment before, during or after the anatomical structure or lumen resumes near normal to normal physiologic function. | 01-15-2015 |
20150018942 | METHOD OF IMPLANTING AN AORTIC STENT - A method of implanting an aortic stent comprising steps of: putting a main tube on a metal guide wire; moving the main tube along the metal guide wire to the descending aorta, the main tube is constrained by a first cover, and first and second tube bifurcations are branched from the main section; removing the first cover; inserting a second and third metal guide wire through the first tube bifurcation into the ascending aorta and branchiocephalic artery respectively; a first and a second tube branch moving into the ascending aorta and the branchiocephalic artery respectively; inserting a fourth and fifth metal guide wire through the first tube bifurcation into the ascending aorta and branchiocephalic artery respectively; a third and a fourth tube branch moving into left common carotid artery and the left subclavian artery respectively; removing a second cover constraining said tube branches. | 01-15-2015 |
20150025621 | Adapter to Actuate a Delivery System - Apparatus for actuating a delivery system are disclosed. The apparatus may comprise an adapter. The adapter may comprise an input, a first actuator, and a second actuator. The adapter may be configured to receive a portion of a delivery system. The adapter may be configured to impart translational motion to the delivery system. The adapter may be configured to impart translational motion to a catheter. The adapter may be configured to be actuated by a motorized device or a drill. The adapter may be configured to actuate multiple delivery systems. The adapter may be configured to at least partially compress a portion of an article such as a prosthetic heart valve. | 01-22-2015 |
20150025622 | Clocking Valve Retainer - Valve retainers and delivery systems with valve retainers are disclosed. In certain embodiments, a portion of the valve retainer can rotate about a central axis of the delivery system relative to a different portion of the valve retainer. In certain embodiments, a first portion of the valve retainer can include a plurality of first orientation markings. In certain embodiments, a second portion of the valve retainer can include a second orientation marking, which can be aligned with a first orientation marking on the first portion of the valve retainer. | 01-22-2015 |
20150025623 | SYSTEM AND METHOD FOR CARDIAC VALVE REPAIR AND REPLACEMENT - A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween. | 01-22-2015 |
20150025624 | TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY DEVICE WITH PASSIVE TRIGGER RELEASE - A delivery device for percutaneously deploying a prosthetic valve includes a sheath, an inner shaft, and a release assembly. The release assembly is disposed between the sheath and the inner shaft, and includes a retraction member, a release member, and a retention member. The retraction member can self-retract in length from an extended condition to a retracted condition. The release member can self-expand from a compressed condition to an expanded condition. The retention member is distal the release member. In a delivery state, the sheath end is distal the retention member, the release member is in the compressed condition and the retraction member in the extended condition to retain the prosthesis. In a deployment state, the sheath end is positioned to permit the release member to self-transition to the expanded condition, allowing the retraction member to self-transition to the retracted condition and release the prosthesis. | 01-22-2015 |
20150032204 | Implantable Tissue Structure Modifiers and Methods for Using the Same - Implantable tissue structure modification devices are provided. Aspects of the tissue structure modification devices include first and second tissue securers separated by a contraction region, wherein the device is configured to be implanted at a cardiac location and assume a first constrained length that is longer than a second relaxed length. Also provided are methods of using the devices for tissue structure modification, as well as delivery systems and kits that find use in the methods. The devices and methods of the invention find use in a variety of different applications, including valve (e.g., mitral valve) structure modification. | 01-29-2015 |
20150039081 | Mitral Valve Prosthesis for Transcatheter Valve Implantation - A transcatheter valve prosthesis is disclosed that has a compressed, delivery configuration and an expanded configuration for deployment within a native heart valve. The valve prosthesis includes a self-expanding frame and a prosthetic valve component. The self-expanding frame includes a valve receiving portion defining an opening therethrough and first and second anchors at opposing ends of the valve receiving portion. The valve receiving portion is substantially planar and the first and second anchors are oriented substantially perpendicular to the valve receiving portion when the valve prosthesis is in the expanded configuration. The prosthetic valve component is disposed within the opening of the valve receiving portion and secured thereto. | 02-05-2015 |
20150039082 | Arrangement, A Loop-Shaped Support, A Prosthetic Heart Valve And A Method Of Repairing Or Replacing A Native Heart Valve - The present disclosure relates to an arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve. With the method or the arrangement, leakage or regurgitation between a prosthetic heart valve and the surrounding valve tissue is prevented. In one embodiment, an arrangement for replacement or repair of a native heart valve is provided, which comprises a loop-shaped support ( | 02-05-2015 |
20150039083 | DEVICES, SYSTEMS AND METHODS FOR REPAIRING LUMENAL SYSTEMS - The disclosure provides systems and related methods for delivering a prosthesis to a target location. Various embodiments of useful valve prostheses are also disclosed. | 02-05-2015 |
20150045878 | METHOD AND APPARATUS FOR RESHAPING A VENTRICLE - Methods are provided for reshaping the left ventricle to a more conical shape to counter the effects of dilation, thereby improving pumping efficiency. In an exemplary embodiment, a reshaping apparatus comprises an implantable body that can be delivered to a dilated left ventricle via the patient's vasculature in a minimally-invasive procedure. When deployed inside the left ventricle, the implantable body applies a longitudinal (downward) force against the inner surface of the left ventricle, thereby causing the left ventricle to distend or elongate downwardly. The implantable body preferably includes an anchor which is deployed adjacent the mitral valve for maintaining the longitudinal force against the inner surface of the left ventricle. | 02-12-2015 |
20150051696 | MEDICAL GUIDEWIRE - A guidewire system may include a guidewire having a relatively stiff proximal section and a relatively flexible distal section joined by a transition region, and a TAVI device slidably disposed on the guidewire. The guidewire may include an expandable element disposed about the transition region. The expandable element may be configured to expand from a collapsed configuration to an expanded configuration. The guidewire may include an expandable element disposed at the distal end. The distal section may be pre-configured to form more than one distal loop. A method of protecting an apex of a left ventricle during a TAVI procedure may include inserting a guidewire into the left ventricle, positioning a transition region adjacent the apex, expanding an expandable element such that the expandable element spans the apex, advancing a TAVI device distally over the guidewire to an aortic valve, and performing a TAVI procedure at the aortic valve. | 02-19-2015 |
20150051697 | SYSTEMS AND METHODS FOR INTRODUCING ELEMENTS INTO TISSUE - Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty. | 02-19-2015 |
20150066136 | Anchoring Studs for Transcatheter Valve Implantation - An anchoring device for use within a vascular structure includes a head having a first surface and a second surface meeting at a common plane, and an anchor including a shaft having a longitudinal axis, a first end connected at a junction to the first surface of the head, and a free end. A harbor space is bounded by the shaft of the anchor, the first surface of the head, a first theoretical plane perpendicular to the longitudinal axis at a spaced distance from the junction and a second theoretical plane tangential to the head at a point in the common plane. The harbor space has an are sufficient to receive a portion of a stented device therein. | 03-05-2015 |
20150066137 | INTEGRATED BALLOON CATHETER INFLATION SYSTEM - An inflation system having two pressure vessels integrated into a balloon catheter. A pressurized chamber and a vacuum chamber are integrally attached to proximal end of the balloon catheter and activated by a common valve or switch. Pressure or vacuum is selectively transmitted to the balloon depending on the valve/switch position. The working fluid may be air, or a combination of air and saline with an intermediate piston/cylinder assembly. The balloon catheter may be a part of a heart valve delivery system with a balloon-expandable heart valve crimped onto the balloon. | 03-05-2015 |
20150066138 | Devices and Methods for Locating and Implanting Tissue Anchors at Mitral Valve Commissure - The present teachings provide devices and methods of locating a mitral valve commissure, and implanting tissue anchors at or near the mitral valve commissure. Specifically, one aspect of the present teachings provides devices and methods for locating a mitral valve commissure percutaneously and allowing a guide wire to be placed across a mitral annulus at the mitral valve commissure. Another aspect of the present teachings provides methods for deploying a tissue anchor across a mitral annulus at a mitral valve commissure, including near the P1 or P3 regions of the posterior mitral annulus. Another aspect of the present teachings further provides methods of plicating a mitral annulus between two or more tissue anchors. | 03-05-2015 |
20150066139 | HEART ANCHOR POSITIONING DEVICES, METHODS, AND SYSTEMS FOR TREATMENT OF CONGESTIVE HEART FAILURE AND OTHER CONDITIONS - According to one embodiment, a heart anchor tensioning device includes a main body and an elongate shaft. A tension member or tether may be inserted through a lumen of the elongate shaft to allow the shaft to be advanced over the tension member and within a body while the main body is positioned outside of the body. The device also includes an anchor coupling mechanism that is configured to engage a heart anchor and move the heart anchor into engagement with a first wall of the heart. The anchor coupling mechanism is able to lock the heart anchor to inhibit proximal movement of the heart anchor along the tension member. The device further includes a tension indicating mechanism that provides an indication of a force being applied to the heart anchor by the device. | 03-05-2015 |
20150066140 | VASCULAR IMPLANT AND DELIVERY METHOD - A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired. | 03-05-2015 |
20150073537 | COLLAPSIBLE CARDIAC IMPLANT AND DEPLOYMENT SYSTEM AND METHODS - A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters. | 03-12-2015 |
20150073538 | ALIGNMENT OF AN IMPLANTABLE MEDICAL DEVICE - A transcatheter valve delivery system includes a longitudinal member extending between a proximal end and a distal end, and having a compartment adjacent the distal end for holding a medical device in a collapsed condition. An alignment element is connected to the longitudinal member and is movable relative to the longitudinal member between a stowed position and a deployed position. In the deployed position, the alignment element is configured to urge against an anatomical surface to position the longitudinal member at a desired location relative to the anatomical surface. | 03-12-2015 |
20150073539 | ALIGNMENT OF AN IMPLANTABLE MEDICAL DEVICE - A medical device delivery system includes an inner shaft having a proximal end and a distal end, a support shaft having a proximal end and a distal end and an articulating assembly disposed between the inner shaft and the support shaft. The support shaft is sized for insertion into the circulatory system of a patient. The articulating assembly includes a first portion at the distal end of the inner shaft and a second portion at the proximal end of the support shaft. The first portion is pivotable relative to the second portion to change orientation of the support shaft relative to the inner shaft. | 03-12-2015 |
20150073540 | METHODS AND APPARATUS FOR ENDOVASCULARLY REPLACING A HEART VALVE - The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor. | 03-12-2015 |
20150081011 | Systems and Methods for Loading a Valve Prosthesis onto a Catheter - A medical device loading system can comprise a first housing, a second housing, and a plate. The first housing comprises a first open end, a first tapered inner surface, and a second open end. The second housing comprises a third open end, a second tapered inner surface, and a fourth open end. The second housing can define a slot between the second tapered surface and the third open end. The plate can be configured to be slidably received within the slot. The loading system can further comprise a first elongated member and a second elongated member. | 03-19-2015 |
20150088245 | Medical Device Delivery Systems and Methods - A delivery system for deploying a medical device includes a first attachment member configured to selectively couple to and radially constrain a first end portion of the medical device. The delivery system also includes a second attachment member configured to selectively couple to and radially constrain a second end portion of the medical device. The first attachment member is configured to move relative to the second attachment member such that the first attachment member applies a first tensile force to the first end portion of a medical device in a first direction and the second attachment member applies a second tensile force to the second end portion of a medical device in a second direction substantially opposite from the first direction. | 03-26-2015 |
20150088246 | DEVICE FOR EXCISION OF HEART VALVE | 03-26-2015 |
20150088247 | TISSUE-ENGINEERED HEART VALVE FOR TRANSCATHETER REPAIR - A single-layer tissue sheet having a puncture strength of 2 kgf to 6 kgf. A valve, such as a heart valve, made of one or more leaflets formed from a single-layer tissue sheet. A method of making a tissue sheet having a puncture strength of 2 kgf to 5 kgf. The ultra-strong tissue sheets described herein have very long culture times, such as in excess of 20 weeks. Valves that comprise one or more leaflets made from the ultra-strong tissue sheets described herein may be delivered via trans-cathete aortic valve implantation. | 03-26-2015 |
20150088248 | HEART VALVE PROSTHESIS - Heart valve prosthesis, comprising a ring-shaped supporting structure ( | 03-26-2015 |
20150088249 | Heart Valve Delivery Catheter With Safety Button - Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. Catheter assemblies according to the present invention can include a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A safety button can be included on the handle assembly to allow for precise and consistent positioning of the prosthetic valve in the body. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. | 03-26-2015 |
20150094801 | STENT-VALVES FOR VALVE REPLACEMENT AND ASSOCIATED METHODS AND SYSTEMS FOR SURGERY - Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided. | 04-02-2015 |
20150100116 | IMPLANT AND METHOD FOR IMPROVING COAPTATION OF AN ATRIOVENTRICULAR VALVE - The invention relates to an implant and a method for improving coaptation of an atrioventricular valve, the atrioventricular valve having a native first leaflet, a native second leaflet and an annulus. The implant comprises a support structure and a flexible artificial leaflet structure mounted to the support structure and shaped to coapt with the native second leaflet. | 04-09-2015 |
20150100117 | TREATMENT CATHETER MEMBER WITH ENCIRCLING FUNCTION - A catheter member ( | 04-09-2015 |
20150105855 | ADJUSTABLE ANNULOPLASTY DEVICES AND ADJUSTMENT MECHANISMS THEREFOR - A method is provided, including, delivering into a heart of a patient an annuloplasty ring structure including a body portion and an adjusting mechanism configured to adjust a size of the body portion of the annuloplasty ring structure, the adjusting mechanism including a housing, and following the delivering, moving the housing with respect to the body portion. Other applications are also described. | 04-16-2015 |
20150112427 | METHODS AND SYSTEMS FOR HEART VALVE THERAPY - Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy. | 04-23-2015 |
20150112428 | TRANSCATHETER VALVE IMPLANTATION ACCESS SHEATHS - An introducer provides access to a surgical site in a patient. The introducer includes a proximal housing configured to be positioned outside the patient and a sheath extending from the proximal housing to a distal end of the introducer. One or more handles may be housed at least partially within the proximal housing and configured to translate axially in proximal and distal directions with respect to the proximal housing. A securing element may be slideably coupled to the sheath and may have a flange extending radially outwardly from the sheath. A radially expanding portion of the sheath may have a first edge, a second edge, and a middle section extending from the first edge to the second edge. The sheath portion may have a rolled configuration in which the middle section at least partially overlies the first edge, and the second edge at least partially overlies the middle section. | 04-23-2015 |
20150112429 | COAPTATION ENHANCEMENT IMPLANT, SYSTEM, AND METHOD - Implants, implant systems, and methods for treatment of mitral valve regurgitation and other valve diseases generally include a coaptation assist body which remains within the blood flow path as the leaflets of the valve move, the valve bodies often being relatively thin, elongate (along the blood flow path), and/or conformable structures which extend laterally from commissure to commissure, allowing the native leaflets to engage and seal against the large, opposed surfaces on either side of the valve body during the heart cycle phase when the ventricle contracts to empty that chamber of blood, and allows blood to pass around the valve body so that blood flows from the atrium to the ventricle during the filling phase of the heart cycle. Separate deployment of independent anchors near each of the commissures may facilitate positioning and support of an exemplary triangular valve body, with a third anchor being deployed in the ventricle. An outer surface of the valve body may accommodate tissue ingrowth or endothelialization, while a fluid-absorbing matrix can swell after introduction into the heart. The valve body shape may be selected after an anchor has been deployed, and catheter-based deployment systems may have a desirable low profile. | 04-23-2015 |
20150112430 | Systems, Devices and Methods for Transcatheter Valve Delivery - A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn. | 04-23-2015 |
20150112431 | SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE - An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device. | 04-23-2015 |
20150112432 | CLOSED BAND FOR PERCUTANEOUS ANNULOPLASTY - A method is provided, which includes providing an annuloplasty ring, which comprises (a) a flexible sleeve, and (b) a contracting assembly. During a percutaneous transcatheter procedure, the flexible sleeve is placed entirely around an annulus of a mitral valve of a subject in a closed loop. The sleeve is fastened to the annulus by coupling a plurality of tissue anchors to a posterior portion of the annulus, without coupling any tissue anchors to an anterior portion of the annulus between left and right fibrous trigones of the annulus. Thereafter, a longitudinal portion of the sleeve is contracted. Other embodiments are also described. | 04-23-2015 |
20150119977 | SYSTEM AND METHOD TO LIMIT CEREBRAL ISCHEMIA - A system to limit cerebral ischemia occurring as a consequence of aortic valve replacement includes an aortic valve having proximal and distal ends, a sleeve having proximal and distal ends, the proximal end of the sleeve disposed at the distal end of the aortic valve, and a filter attached to the distal end of the sleeve to receive blood and particles passing from the proximal end of the sleeve to the distal end of the sleeve and to separate the particles from the blood. A related method includes introducing a system into a heart of a patient, the system comprising an aortic valve having proximal and distal ends and a sleeve having a proximal end disposed at the distal end of the valve, implanting the valve in an aortic valve annulus, and filtering blood that has passed through the valve into the sleeve. | 04-30-2015 |
20150119978 | APPARATUS AND METHODS FOR DELIVERY OF TRANSCATHETER PROSTHETIC VALVES - In some embodiments, an apparatus includes a catheter assembly and a handle assembly that can be removably coupled to the catheter assembly. A valve holding tube defines a lumen configured to receive a prosthetic mitral valve in a compressed configuration and can be removably coupled to a distal end portion of the handle assembly. The valve holding tube can be received within a hub of the catheter assembly when coupled to the handle assembly. The actuator when actuated is configured to cause the tensioning unit to travel along a traveler strap of the catheter assembly moving the handle assembly distally such that a distal end of an elongate shaft of the handle assembly moves the prosthetic mitral valve distally out of the valve holding tube and out a distal end of the sheath such that the prosthetic mitral valve is free to move to a biased expanded configuration. | 04-30-2015 |
20150119979 | HEART VALVE REPAIR SYSTEM - Techniques are described for use with one or more sutures. For some applications, techniques are described for fixedly-coupling two or more sutures to each other. For some applications, such techniques are used for treating a heart valve of a subject. Techniques are also described for treating a heart valve of a subject by coupling leaflets of the heart valve to a support using tissue-piercing elements. Other embodiments are also described. | 04-30-2015 |
20150127092 | CATHETER SYSTEM FOR INTRODUCING AN EXPANDABLE HEART VALVE STENT INTO THE BODY OF A PATIENT, - The invention relates to catheter system for introducing an expandable heart valve stent ( | 05-07-2015 |
20150127093 | MAGNETIC RETAINING MECHANISMS FOR PROSTHETIC VALVES - Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native chordae tendineae and/or leaflets of a valve. The support member can comprise a flexible, distensible material to reduce abrasion and other mechanical damage to surrounding structures. A locking member may be used to couple both ends of the support member, forming a support ring. The support member may have two magnetic end portions which can be magnetically coupled to form a support ring. An expandable prosthetic heart valve can be delivered into the native heart valve and expanded within the support band, thereby causing one or more of the native chordae tendineae and/or leaflets of the native heart valve to be frictionally secured between the support ring and the expanded prosthetic heart valve. | 05-07-2015 |
20150127094 | SYSTEMS AND METHODS FOR DELIVERING A MEDICAL IMPLANT - The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system. | 05-07-2015 |
20150134052 | LOW PROFILE TRANSCATHETER HEART VALVE - An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame. | 05-14-2015 |
20150134053 | TRANSFEMORAL MITRAL VALVE REPAIR DELIVERY DEVICE - A device for repair of a heart valve leaflet includes an elongated catheter assembly having a proximal end and a distal end, and a tip at the distal end of the catheter assembly. A capture mechanism having a first free end and a second free end is rotatably coupled to a distal end of the tip. A plication mechanism has an open configuration and a closed configuration, and extends between the first free end and the second free end of the capture mechanism when in the open configuration. The device may also include a clip housing at a proximal end of the tip configured to hold a clip therein. | 05-14-2015 |
20150134054 | PNEUMATICALLY POWER-ASSISTED TAVI DELIVERY SYSTEM - A delivery device for a collapsible prosthetic heart valve may include an operating handle and a catheter assembly. The handle may include a housing, a piston cylinder, a piston longitudinally slidable within the piston cylinder, the piston and the piston cylinder together defining at least one pressure chamber, a deployment actuator coupled to the housing and rotatable relative thereto, and a pneumatic switch adapted to provide a pressurized fluid to the pressure chamber to apply a longitudinal force to the piston. The catheter assembly may include a first shaft around which a valve-receiving compartment is defined, the first shaft being operatively connected to the housing, and a distal sheath operatively connected to the piston, the distal sheath being moveable between a closed condition covering the compartment and an open condition uncovering the compartment. Longitudinal movement of the piston may move the distal sheath between the closed and open conditions. | 05-14-2015 |
20150134055 | Tissue fastening systems and methods utilizing magnetic guidance - Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty. | 05-14-2015 |
20150134056 | CATHETER DELIVERABLE ARTIFICIAL MULTI-LEAFLET HEART VALVE PROSTHESIS AND INTRAVASCULAR DELIVERY SYSTEM FOR A CATHETER DELIVERABLE HEART VALVE PROSTHESIS - A heart valve prosthesis includes a collapsible stent and a one-piece multi-leaflet valve. The stent includes at least one length of wire having a series of turns forming a spring-like stent. The one-piece multi-leaflet valve is attached to the stent and includes a cylinder of polyester material secured thereto at three points. The stent is collapsible in a radial direction between a contracted state and an expanded state. The contracted state has a radial dimension smaller than a radial dimension of the expanded state. The stent is spring biased toward the expanded state such that it occupies an active state when implanted into a heart. The active state has a radial dimension that is between the radial dimension of the contracted state and the radial dimension of the expanded state such that a radial load generated by the bias of the collapsible stent is sufficient to retain the heart valve prosthesis in the heart. | 05-14-2015 |
20150142101 | Adjustable Heart Valve Implant - Systems and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion coupled to a proximal end of a shaft, and an anchor portion coupled to a distal end of the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance between the prosthetic valve portion and the anchor portion can be adjusted, and/or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications. | 05-21-2015 |
20150148894 | CATHETER DELIVERY SYSTEM FOR INTRODUCING AN EXPANDABLE HEART VALVE PROSTHESIS AND MEDICAL DEVICE FOR THE TREATMENT OF A HEART VALVE DEFECT - The invention relates to an operating handle ( | 05-28-2015 |
20150148895 | CARDIAC VALVE PROSTHESIS - A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site. | 05-28-2015 |
20150148896 | AORTIC INSUFFICIENCY REPAIR DEVICE AND METHOD - This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible. | 05-28-2015 |
20150289971 | PROFILE ALTERING TIP FOR A DELIVERY SYSTEM - A profile altering tip is provided for a delivery system. The tip defines a first profile with a generally conical shape and a second profile with an expanded profile. During use of the delivery system, a tip profile control assembly can alter the tip from the first profile to the second profile. | 10-15-2015 |
20150289975 | Profile Altering Tip for a Delivery System - A profile altering tip is provided for a delivery system. The tip defines a first profile with a generally conical shape and a second profile with a generally round shape. During use of the delivery system, a tip profile control assembly can alter the tip from the first profile to the second profile. | 10-15-2015 |
20150297345 | Insertion Tool for a Heart Valve - An insertion tool for a heart valve includes a solid body portion in a first configuration having a first size and shape. The solid body portion in a second configuration having a second size smaller than the first size; said solid body portion comprises two or more parts; in the first configuration, the solid body portion provides a support portion for supporting a valve to be inserted by the insertion tool, and an insertion surface which protrudes distally from the support portion; the insertion surface is tapered from a small cross-section distally of the support portion to a greater cross section proximally to the support portion; in use the insertion surface elastically expands the periphery of an annulus into which the valve is to be fitted. | 10-22-2015 |
20150297346 | HINGED TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY SYSTEM - A machined or molded hinge design, for use with a delivery device, which allows for controlled deflection of a large diameter catheter. With embodiments in which the delivery device is employed to implant a prosthetic heart valve, deflection of the catheter allows for central alignment of the delivery system in the native annulus during deployment of the bioprosthesis. | 10-22-2015 |
20150305861 | Device and Method for Temporary or Permanent Suspension of an Implantable Scaffolding Containing an Orifice for Placement of a Prosthetic or Bio-Prosthetic Valve - In a surgical method for improving cardiac function, an implantable scaffold or valve support device is inserted inside a patient's heart and attached to the heart in a region adjacent to a natural mitral or other heart valve. The scaffold or valve support device defines an orifice and, after the attaching of the scaffold or valve support device to the heart, or temporary support while native valve leaflets and/or subvalvular structures are captured, a prosthetic or bio-prosthetic valve seated in the orifice, and the native valve may be retracted into the scaffold/replacement assembly to create a gasket for sealing the complex. | 10-29-2015 |
20150305863 | INTRAVASCULAR INTRODUCER DEVICES - Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal. | 10-29-2015 |
20150305864 | REPLACEMENT HEART VALVES, DELIVERY DEVICES AND METHODS - A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve. | 10-29-2015 |
20150305865 | METHOD OF DELIVERING A PROSTHETIC HEART VALVE - A method of delivering a prosthetic heart valve to a native aortic valve is disclosed. The prosthetic heart valve comprises a radially compressible and expandable metallic stent and a flexible valvular structure. A delivery system comprises a selectively steerable section and a pusher member extending through a central lumen of the steerable section. The prosthetic heart valve is compressed and inserted into a distal end portion of the delivery system. The delivery system and prosthetic heart valve are advanced through a femoral artery and around an aortic arch. A pull wire is actuated for selectively controlling a curvature of the steerable section during advancement around the aortic arch. The pusher member is advanced for ejecting the prosthetic heart valve from the delivery system into the native aortic valve, wherein the prosthetic valve self-expands after ejection. | 10-29-2015 |
20150305867 | PROSTHETIC HEART VALVE DELIVERY APPARATUS - Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body. | 10-29-2015 |
20150305869 | DEVICE FOR PLACING A SEAL AROUND AN IMPLANT IN A BLOOD CIRCULATION PASSAGE, AND ASSOCIATED TREATMENT KIT | 10-29-2015 |
20150313711 | HOLDER AND DEPLOYMENT SYSTEM FOR SURGICAL HEART VALVES - A holder for a hybrid heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The hybrid heart valve includes a non-expandable, non-compressible prosthetic valve and a self-expandable anchoring stent, thereby enabling attachment to the annulus without sutures. A first suture connects the holder to the valve and constricts an inflow end of the anchoring stent. A second suture connects the holder to the valve and extends down three holder legs to loop through fabric on the valve. Both sutures may loop over a single cutting well on the holder so that severing the first and second sutures at the single cutting well simultaneously releases the tension in the first suture, permitting the inflow end of the anchoring stent to expand, and disconnects the valve holder from the prosthetic heart valve. | 11-05-2015 |
20150313712 | ERGONOMIC MITRAL HEART VALVE HOLDERS - A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window for enhanced access to the commissure posts and leaflets. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation. | 11-05-2015 |
20150320414 | METHODS OF ANCHORING CARDIAC IMPLANTS USING KNOTLESS SUTURE FASTENERS - Devices and methods for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots are disclosed. The devices are particularly well suited for traditional surgery or minimally invasive surgery, and improve the ease of implantation by eliminating surgical knots a clinician would normally tie in the limited space in and around the implant site. The devices have opposed the clamp halves surrounded by a coil spring. Sutures pass between the clamp halves and the coil spring has an inner coil diameter sufficient to compress the sutures between the clamp. A retention member positioned between the clamp halves maintains a minimum space and therebetween to enable the locking device to be slid along the sutures into position, and to adjust the tension of the sutures therethrough. A delivery tool may be used to deliver and deploy the locking devices. | 11-12-2015 |
20150320553 | PROSTHETIC VALVE FOR REPLACING MITRAL VALVE - A prosthetic apparatus configured for implantation in the native mitral valve region of the heart includes a main body that is self-expandable from a compressed state to a radially expanded state. The prosthetic apparatus comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body for capturing a native valve leaflet between the anchor and an outer surface of the main body. In one preferred method of implantation, the prosthetic apparatus is rotated within the native mitral valve region such that a portion of the anchor moves horizontally behind adjacent chordae for anchoring the prosthetic apparatus in the native mitral valve. | 11-12-2015 |
20150320556 | PROSTHETIC HEART VALVE - Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed. | 11-12-2015 |
20150327997 | SYSTEM AND METHOD FOR PLACING A PROSTHETIC AORTIC VALVE - A system and method including a guide wire having a plurality of sensors attached near an end of the guide wire, and a processor configured to determine a position of a body component and a position of a catheter moving along the guide wire based on the signals received from the plurality of sensors. Feedback information can be generated based on these determined positions to help guide a medical procedure. | 11-19-2015 |
20150327998 | METHODS OF DELIVERING AND RELEASING A CARDIAC IMPLANT TO A NATIVE VALVE ANNULUS - An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle. | 11-19-2015 |
20150335425 | SYSTEMS AND DELIVERY HANDLES FOR DELIVERING PROSTHETIC HEART VALVES DISPOSED ON VALVE HOLDERS - A system delivering a prosthetic heart valve includes a delivery handle, a heart valve, and a valve holder. The delivery handle includes a rod, a button, and a valve holder attachment interface, where the button is configured to move between a first position and a second position along an axial length of the rod, and the valve holder attachment interface is mechanically coupled to the button and configured to move between an engaged position and a disengaged position. The heart valve includes a prosthetic valve. The valve holder is connected to a proximal end of the heart valve and includes a boss, a holder ring, and a handle attachment interface. The holder ring includes the heart valve mounted thereto and is coupled to the boss, and the handle attachment interface is formed on the boss and is configured to receive and mate with the valve holder attachment interface. | 11-26-2015 |
20150335426 | APPARATUS AND SET FOR FOLDING OR UNFOLDING A MEDICAL IMPLANT COMPRISING A CLAMPING MECHANISM, IMPLANT AND METHOD - The present invention relates to an apparatus ( | 11-26-2015 |
20150342717 | TEMPORARY VALVE AND FILTER ON GUIDE CATHETER - A temporary valve and a filtration device can be added to a delivery catheter or guide catheter to improve hemodynamics and provide embolic protection. Both the valve and filter can mount onto the outer diameter of a delivery or guide catheter, which offers several distinct advantages. First, the inner lumen of the delivery or guide catheter remains unaffected, thereby allowing the standard procedure steps to take place without any changes or interruptions, or with minimal changes or interruptions. | 12-03-2015 |
20150342731 | DEVICE FOR THE IMPLANTATION AND FIXATION OF PROSTHETIC VALVES - A device for the tranavascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent ( | 12-03-2015 |
20150342735 | DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE - Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others. | 12-03-2015 |
20150342736 | PROSTHESIS, DELIVERY DEVICE AND METHODS OF USE - Disclosed herein are embodiments of a prosthesis and delivery device, as well as methods of use. The delivery device can be composed of an inner retention assembly configured to carry an expandable prosthesis to an in situ target location. The inner retention assembly can slide within an outer elongate hollow member which can cover the expandable prosthesis. The outer elongate hollow member can further be longitudinally collapsed into a receiving member located at the distal end of the outer elongate hollow member. | 12-03-2015 |
20150351903 | DEVICES, SYSTEMS AND METHODS FOR HEART VALVE REPLACEMENT - A prosthetic heart valve device ( | 12-10-2015 |
20150351906 | VENTRICULARLY-ANCHORED PROSTHETIC VALVES - Apparatus is provided, including: (A) a valve body ( | 12-10-2015 |
20150351907 | DEVICE FOR PLACING A SEAL AROUND AN IMPLANT IN A BLOOD VESSEL, AND ASSOCIATED TREATMENT KIT - A device for placing a seal around an implant in a blood vessel, and associated treatment kit are provided. This device ( | 12-10-2015 |
20150359629 | TWO STAGE ANCHOR AND MITRAL VALVE ASSEMBLY - Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy. | 12-17-2015 |
20150366665 | PROSTHETIC VALVE, DELIVERY APPARATUS AND DELIVERY METHOD - A delivery catheter for a prosthetic heart valve, the valve expandable from a collapsed condition for delivery to an ex paneled condition for implantation, the delivery catheter comprising: a holder for engaging the valve in the collapsed state of the valve, the holder configured such that (i) in response to a radial compression force exerted thereon, the holder has a first shape defining an exposed engagement region for engaging at least a portion of the collapsed prosthetic heart valve for restraining axial displacement of the prosthetic valve in at least one axial direction of the catheter, and (ii) in response to removal of the radial compression force upon expansion of the valve, at least a portion of the holder transitions to a second shape. | 12-24-2015 |
20150366666 | MITRAL VALVE IMPLANTS FOR THE TREATMENT OF VALVULAR REGURGITATION - The invention relates in some aspects to a device for use in the transcatheter treatment of mitral valve regurgitation, including steerable guidewires, implantable coaptation assistance devices, anchoring systems for attaching a ventricular projection of an implantable coaptation device, a kit, and methods of using an implantable coaptation assistance device among other methods. | 12-24-2015 |
20150366667 | ENDOLUMINAL CARDIAC AND VENOUS VALVE PROSTHESES AND METHODS OF MANUFACTURE AND DELIVERY THEREOF - This invention relates to prosthetic cardiac and venous valves and a single catheter device and minimally invasive techniques for percutaneous and transluminal valvuloplasty and prosthetic valve implantation. | 12-24-2015 |
20150374491 | INTRACARDIAC CAGE AND METHOD OF DELIVERING SAME - A method of preventing ingress of material into the left atrium of a heart includes providing a delivery sheath, advancing the sheath distal end through an opening between the right atrium and the left atrium of the heart, providing an expandable cage, delivering the expandable cage to the left atrium, and expanding the expandable cage within the left atrium. The expandable cage includes a proximal end, a distal end, and a plurality of supports extending therebetween. The expandable cage also includes a first membrane provided at its proximal end and a second membrane provided at its distal end. The expandable cage has a collapsed configuration so that it can be received within the lumen of the delivery sheath, and an expanded configuration for deployment within the heart. When expanded, the first membrane is positioned at an opening between the left and right atria of the heart, and the second membrane is positioned at the ostium of the left atrial appendage. The first membrane substantially prevents passage of blood between the atria and the second membrane prevents passage of embolic material from the left atrial appendage into the left atrium of the heart. | 12-31-2015 |
20150374492 | DELIVERY AND RETRIEVAL SYSTEMS FOR COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES - A system for delivering a collapsible and re-expandable prosthetic heart valve into a patient includes a valve support structure around which the valve is disposed in a collapsed condition. A sheath structure surrounds the collapsed valve, but can be moved relative to the valve to uncover it for expansion at the desired implant site in the patient. The sheath structure may be variously mounted and moved to deploy the valve in various ways. For example, the sheath structure may include multiple parts, each of which can be moved separately to separately deploy various parts of the valve. The apparatus may have other aspects, such as the ability to reverse deployment of the valve, the ability to pass other instrumentation through the valve delivery apparatus, the ability to be smoothly withdrawn from the patient after deployment of the valve, etc. | 12-31-2015 |
20160000561 | TRANSAPICAL PASSIVE ARTICULATION DELIVERY SYSTEM DESIGN - A delivery system ( | 01-07-2016 |
20160000562 | CATHETER BASED APICAL APPROACH HEART PROSTHESES DELIVERY SYSTEM - A delivery system for rapid placement of heart implants is provided that includes a delivery platform. The delivery system includes a tubular catheter body, a piercing member, and a delivery platform. The tubular catheter body is sufficiently long and flexible to be advanced from a peripheral blood vessel access site to an atrium of the heart. The piercing member is configured to create a transapical channel from an internal apical portion of a ventricle to an outside heart wall. The delivery system includes an elongate tension member and an enlargeable member disposed on a distal portion of the elongate tension member. The enlargeable member is configured to be enlarged in a pericardial space of an intact chest wall to cover an area of the outside heart wall surrounding an opening of the transapical channel. When tensioned, the tension member provides a stable zone for positioning a heart implant within the heart. | 01-07-2016 |
20160000563 | TELESCOPING CATHETER DELIVERY SYSTEM FOR LEFT HEART ENDOCARDIAL DEVICE PLACEMENT - A transseptal catheter delivery system includes an elongate first tubular member and an elongate second tubular member receivable within the first tubular member. The first tubular member includes an adjustable portion adjacent a distal end. The second tubular member is adapted to receive an instrument to be placed in the left ventricle, and includes a curved portion adjacent its distal end in a relaxed state. The adjustable portion is deflectable toward the atrial septum to guide a puncturing tool and/or guide insertion of the second tubular member through a septal puncture into the left atrium. Within the left atrium, the curved portion is oriented toward the left ventricle to guide insertion of a guide wire, and subsequently the second tubular member, into the left ventricle. Methods of transvenously accessing a left ventricle are also provided. | 01-07-2016 |
20160000564 | DELIVERY SYSTEMS FOR CARDIAC VALVE SUPPORT DEVICES - The present device provides a delivery device ( | 01-07-2016 |
20160000565 | Annuloplasty Ring Holder - An annuloplasty ring holder including a head having an upper surface and an annuloplasty ring receiving surface facing opposite the upper surface. The annuloplasty ring holder also includes means for attaching an annuloplasty ring to the annuloplasty ring receiving surface. The means for attaching an annuloplasty ring to the annuloplasty ring receiving surface may include one or more suture guides operatively associated with the head and configured to position one or more sutures to removably associate an annuloplasty ring with the annuloplasty ring receiving surface. The head may include a central hub and more than one spoke radiating out from the central hub. If the head is thus configured, each spoke will include a portion of the annuloplasty ring receiving surface. | 01-07-2016 |
20160008128 | HEART VALVE PROSTHESES | 01-14-2016 |
20160008129 | METHOD AND APPARATUS FOR PERCUTANEOUS DELIVERY AND DEPLOYMENT OF A CARDIOVASCULAR PROSTHESIS | 01-14-2016 |
20160008131 | PROSTHETIC HEART VALVE AND SYSTEMS AND METHODS FOR DELIVERING THE SAME | 01-14-2016 |
20160008132 | MULTIPLE ANCHOR DELIVERY TOOL | 01-14-2016 |
20160015512 | SUTURELESS VALVE PROTHESIS DELIVERY DEVICE AND METHODS OF USE THEREOF - Devices and methods for delivering a sutureless valve ( | 01-21-2016 |
20160015514 | PROSTHETIC MITRAL VALVE WITH ADJUSTABLE SUPPORT - Disclosed is an implantable mitral valve having an adjustable support. The support comprises a plurality of pairs of adjacent struts joined at apexes and a plurality of anchors for tissue engagement. The implant is adjustable to a first, reduced diameter for transluminal navigation and delivery to the left atrium of a heart. The implant may then expand to a second, enlarged diameter for the step of embedding the anchors into tissue surrounding and/or including the mitral valve. The implant may then be adjusted to a third, intermediate diameter, pulling the tissue radially inwardly, thereby reducing the native mitral valve annulus and supporting the prosthetic mitral valve. | 01-21-2016 |
20160022419 | SYSTEMS AND METHODS FOR DELIVERY OF ANNULOPLASTY RINGS - Systems and methods for percutaneous, transcatheter heart valve repair are disclosed. A system may include a catheter, an adjustable ring, and a stabilizer. The adjustable ring may include a body member that is transitionable from an insertion geometry to an operable geometry. The insertion geometry may be configured to allow percutaneous passage of the ring into the heart. The operable geometry may have an expanded state to conform to an annulus of a target valve and a contracted state to reduce a diameter of the annulus. The adjustable ring may also include a plurality of anchors deployable in the operable geometry to engage the annulus. The stabilizer may include a plurality of prongs configured to engage the ring in the operable geometry within the heart to enable percutaneous manipulation of the ring to orient and position the ring in intimate contact with the annulus. | 01-28-2016 |
20160030176 | Implant and method for improving coaptation of an atrioventricular valve - The invention relates to an implant and a method for improving coaptation of an atrioventricular valve, the atrioventricular valve having a native first leaflet, a native second leaflet and an annulus. The implant comprises a support structure and a flexible artificial leaflet structure mounted to the support structure and shaped to coapt with the native second leaflet. | 02-04-2016 |
20160038285 | SYSTEMS AND METHODS FOR RESHAPING A HEART VALVE - The present disclosure includes a device for reshaping a heart valve. The device may include a central ring about a central axis and a plurality of arms coupled to the central ring, each of the arms coupled to the central ring at a pivot point at a first end of the arm, the arm comprising an attachment feature at a second point along the arm, the pivot point configured to allow movement of the arm about the pivot point through a plane extending radially from the central axis through the arm. Additionally, the plurality of arms may be contractable and may be extendable such that the hooks extend beyond a dilated heart valve. The present disclosure also includes associated methods and systems. | 02-11-2016 |
20160038286 | METHODS, DEVICES, AND SYSTEMS FOR PERCUTANEOUSLY ANCHORING ANNULOPLASTY RINGS - Apparatus, systems, and methods are provided for percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer tube, an inner body member, and an anchor deployment system. The outer tube includes a plurality of windows and has an axis along its length. The internal body member includes a plurality of anchors formed perpendicular to the axis. The anchor deployment system selectively rotates the internal body member with respect to the axis of the outer tube. The rotation deploys the plurality of anchors through the plurality of windows. | 02-11-2016 |
20160038287 | DEVICES AND METHODS FOR TREATING FUNCTIONAL TRICUSPID VALVE REGURGITATION - Disclosed here are devices and methods for treating functional tricuspid valve regurgitation and related conditions. Disclosed devices are adapted for applying force to an area of a patient's heart along or near the atrioventricular groove, and can include a tensioning element configured to be delivered by a flexible member guided through a catheter and positioned generally along or near the atrioventricular groove, and a compression member positionable along the tensioning element and over a desired segment of the atrioventricular groove to develop force to be applied to an adjacent area of the heart by selective tensioning of the tensioning element. | 02-11-2016 |
20160045311 | PROSTHETIC IMPLANT DELIVERY DEVICE - The disclosure includes an arrangement for a handle for a catheter system that includes a first member and a second member. The handle can include a screw member positioned within the handle and configured for rotation about an axis. The screw member can include an internal thread. A carriage can be positioned within the screw member. The carriage can engage the internal thread and can be coupled to the first member. An alignment member can extend within the screw member to limit rotation of the carriage about the axis as the screw member is rotated. Rotation of the screw member in a first direction about the axis can cause the carriage to move in a first longitudinal direction within the screw member causing the first member to move in the first longitudinal direction relative to the handle. | 02-18-2016 |
20160045315 | Device For Carrying Out A Transapical Mitral Valve Annuloplasty - The device is intended to be positioned in a sealed introducer arranged in the thoracic cavity between two ribs in order to penetrate into the left ventricle, passing through the apex of the heart. According to the invention, the device includes a body having a handle and at least one control member capable of acting on an assembly for installing and securing a braid to the mitral annulus by means of suturing elements, the assembly has a mechanism capable of enabling the extraction of a suture through the mitral valve while also being capable of enclosing the braid and becoming anchored to the periphery of the mitral annulus under the clamping effect of the suture, exerting two opposing pressure-bearing forces. | 02-18-2016 |
20160051364 | RAPID EXCHANGE TRANSCATHETER VALVE DELIVERY SYSTEM - A delivery device for implanting a prosthetic heart valve. The device includes an inner shaft assembly, an outer sheath and a connector assembly. The inner shaft assembly defines a guide wire lumen. The outer sheath is slidably received over the inner shaft assembly, and forms an exit port proximate a distal end thereof. The connector assembly establishes a guide wire passageway between the guide wire lumen and the exit port. The connector assembly is configured to permit sliding movement of the outer sheath relative to the inner shaft assembly when deploying the prosthetic heart valve. The connector assembly can include first and second tubes that are slidable relative to one another in facilitating movement of the outer sheath relative to the inner shaft assembly. | 02-25-2016 |
20160058540 | APPARATUS AND PROCEDURE FOR TRAPPING EMBOLIC DEBRIS - Apparatus for implanting a heart valve and removing debris from a blood vessel, composed of: a collapsible and deployable filter for blocking debris in a blood vessel in a patient's body; a circular cuff coupled to a small diameter end of the filter and defining a through passage extending from the small diameter end, the cuff having, at a first end, an internal diameter coaxial with a circular opening at the small diameter end of the filter; a first sheath for housing the filter in its collapsed state and having a length sufficient to extend out of a patient's body when the filter is at a desired location in a blood vessel; and an assembly for implanting a prosthetic valve in the patient's heart, said assembly comprising a second sheath and a catheter housed in the second sheath and carrying an implantable valve. | 03-03-2016 |
20160058557 | APPARATUS AND METHOD FOR GUIDE-WIRE BASED ADVANCEMENT OF A ROTATION ASSEMBLY - Apparatus is provided, comprising (1) a guide member, (2) a tissue-adjustment mechanism having (a) an upper surface and a lower surface, (b) at least one first opening at the upper surface, (c) at least one second opening at the lower surface, and (4) a channel extending between the first and second openings, the channel facilitating advancement of the tissue-adjustment mechanism along the guide member; and (3) at least one repair chord coupled at a first portion thereof to the tissue-adjustment mechanism and having at least a first end that is configured to be coupled to a portion of tissue of a patient, the repair chord being configured to adjust a distance between the portion of tissue and the tissue-adjustment mechanism, in response to adjustment of the repair chord by the tissue-adjustment mechanism. Other embodiments are also described. | 03-03-2016 |
20160067039 | METHOD AND APPARATUS FOR REPAIRING A MITRAL VALVE - A method for repairing a mitral valve, the method comprising:
| 03-10-2016 |
20160067040 | VALVE LOCKING MECHANISM - A medical device may include an elongate delivery sheath and a valve replacement implant disposed within a lumen of the delivery sheath, the implant including an anchor member reversibly actuatable between a delivery configuration and a deployed configuration. The implant may include at least one locking element configured to lock the anchor member in the deployed configuration, and at least one actuator element configured to engage the at least one locking element and actuate the anchor member between the delivery configuration and the deployed configuration. The at least one actuator element may include an unlocking member configured to compress a first locking portion of the at least one locking element to unlock the anchor member from the deployed configuration. | 03-10-2016 |
20160067041 | REPOSITIONING OF PROSTHETIC HEART VALVE AND DEPLOYMENT - A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has an annulus section with a relatively small cross-section, and an aortic section with a relatively large cross-section. The valve assembly, including a cuff and a plurality of leaflets, is secured to the stent in the annulus section such that the valve assembly can be entirely deployed in the native valve annulus and function as intended while at least a portion of the aortic section is held by the delivery device in a manner that allows for resheathing. The configuration of the prosthetic valve is such that the valve leaflets can fully coapt and the valve can function properly even when the stent and/or valve assembly become distorted upon deployment or use. | 03-10-2016 |
20160067043 | DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS INCLUDING THE USE OF MAGNETIC TOOLS - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. | 03-10-2016 |
20160074157 | METHODS AND APPARATUSES FOR DEPLOYING MINIMALLY-INVASIVE HEART VALVES - A medical assembly for replacing a native heart valve of a patient can include a deployment mechanism and a radially expandable and contractable prosthetic heart valve coupled to the deployment mechanism. The prosthetic heart valve can comprise a self-expandable stent body and a plurality of leaflet-forming membranes. The assembly can further include a storage container, wherein the prosthetic heart valve and the deployment mechanism are disposed in the storage container. | 03-17-2016 |
20160074158 | DEVICES AND METHODS FOR COLLAPSING PROSTHETIC HEART VALVES - A crimping tool for use with a collapsible prosthetic valve having a stent frame with a plurality of cell openings, and a valve structure assembled in the stent frame. The crimping tool includes a plurality of resilient tines defining an array around a longitudinal axis of the crimping tool. The array has a first cross-section in an expanded state and a second cross-section less than the first cross-section in a collapsed state. The plurality of tines are adapted to intersect the plurality of cell openings in an assembled position of the crimping tool on the prosthetic valve to prevent pinching of the valve structure by the stent frame as the prosthetic valve is collapsed. | 03-17-2016 |
20160074163 | METHODS AND APPARATUSES FOR DEPLOYING MINIMALLY-INVASIVE HEART VALVES - A system for delivering and deploying a self-expandable heart valve to a site of implantation such as the aortic annulus includes a deployment mechanism that engages the valve and regulates the rate of expansion of both the proximal and distal ends thereof. The heart valve may be a rolled-type valve and the deployment mechanism may include a plurality of distal fingers and a plurality of proximal fingers that engage the outer layer of the heart valve. Controlled radial movement of the fingers regulates the unwinding of the rolled heart valve. The fingers may be removed prior to inflation of a balloon to fully expand the valve, or the fingers may be repositioned to the inside of the valve for this purpose. The deployment mechanism may include an umbrella structure that forces the rolled valve outward into its fully expanded configuration. Alternatively, a gear shaft that engages one or more gear tracks on the valve may be utilized to regulate expansion of the valve. A stabilization balloon may be used to axially and radially locate the deployment mechanism relative to the site of implantation. Methods of operation of the delivery and deployment mechanism include regulating the rate of self-expansion of the valve and forcing the valve outward into its fully expanded configuration utilizing the same or different means. | 03-17-2016 |
20160074164 | HEART VALVE ASSISTIVE PROSTHESIS - A device for placing in a cardiac valve to assist operation of natural cardiac valve leaflets, the device including a frame for anchoring the device, configured to be placed upstream of the cardiac annulus and shaped to prevent the frame from shifting downstream of the cardiac valve annulus, and at least one anchor extension attached to the frame, the anchor extension configured to extend through the leaflets of the cardiac valve at commissures of the cardiac valve and behind the natural leaflets, preventing the anchor extensions from shifting back from the downstream side of the annulus to the upstream side of the annulus. Related apparatus and methods are also described. | 03-17-2016 |
20160081800 | MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE - A device, kit and method may employ an implantable device (e.g., annuloplasty implant) and a tool to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). Tissue anchors are guided into precise position by an intravascularly deployed anchor guide frame and embedded in an annulus. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in a generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may move a posterior leaflet anteriorly and an anterior leaflet posteriorly, improving leaflet coaptation to eliminate mitral regurgitation. | 03-24-2016 |
20160089237 | TRANS-APICAL IMPLANT SYSTEMS, IMPLANTS AND METHODS - A trans-apical implant includes a spacer defining spacer cavity configured to be expanded from a retracted position, a shaft extending from the spacer, the shaft defining an inflation lumen fluidly coupled to the spacer cavity and configured to be fluidly coupled to an expansion medium source, and a spacer valve assembly disposed within at least one of the spacer or shaft, the spacer valve assembly configured to allow selectively allow an expansion medium to flow into the spacer cavity to be selectively expand the spacer from a retracted position to an expanded position. | 03-31-2016 |
20160089239 | METHOD FOR TREATING A MITRAL VALVE - A method of using a device to improve the function of a heart valve is disclosed. In one preferred embodiment, the method includes positioning a prosthetic insert member between leaflets of mitral valve. The insert member has an elongated cross-sectional profile for conforming to gap between leaflets of a mitral valve. The device also includes an anchoring member for attachment to heart tissue for maintaining the insert member in the mitral valve. The insert member is used to plug the gap between the leaflets of the mitral valve and thereby reduce undesirable regurgitation while allowing the leaflets to function in a substantially normal manner. An anchoring member secures the prosthetic insert member to a heart wall. The anchoring member preferably includes a plurality of tissue penetrating hooks or prongs. | 03-31-2016 |
20160095700 | IMPLANT, INTENDED TO BE PLACED IN A BLOOD CIRCULATION PASSAGE, COMPRISING A SYSTEM FOR SEPARATING THE PROXIMAL ARMS - The implant comprises a tubular proximal sleeve, extending between a proximal end and a distal end, and deployable between a contracted configuration and a deployed configuration. Proximal arms each extend between an end connected to the distal end, and a free end positioned past the distal end. At least one proximal arm is elastically deformable between a separating position and an anchoring position, the radial distance between its free end and its connected end being larger in the separating position rather than in the anchoring position. This proximal arm is elastically recalled toward its anchoring position. The implant includes: a first stop, supported by this proximal arm, and a second stop, cooperating with the first stop in the contracted configuration to keep this proximal arm in its separating position, and releasing this first stop in the deployed configuration. | 04-07-2016 |
20160095702 | Stentless Support Structure - A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve. | 04-07-2016 |
20160095703 | FLEXIBLE CATHETERS AND METHODS OF FORMING SAME - A delivery device for a collapsible prosthetic heart valve includes an inner shaft having a proximal end and a distal end, an outer shaft disposed around the inner shaft and longitudinally moveable relative to the inner shaft, and a distal sheath disposed about a portion of the inner shaft and forming a compartment with the inner shaft, the compartment being adapted to receive the prosthetic heart valve. At least one of the outer shaft or the distal sheath may have a pattern of cutouts formed therein, the pattern including at least one ring around a circumference of the at least one of the outer shaft or the distal sheath, the at least one ring having at least one of the cutouts. | 04-07-2016 |
20160095704 | Systems and Methods for Affixing A Prosthetic to Tissue - Systems and methods recited herein provide for affixation of a prosthetic valve to surrounding tissue, by at least one anchor and an anchor deployment device. The prosthetic valve device may be compliant with native tissue and may receive the at least one anchor in at least one anchor receptacle to affix the prosthetic valve to native tissue. The anchor may include a distal tip, a proximal head, and a tension component, such that upon deployment into tissue the tension component is situated in a tensioned state to exert a pulling force on the distal end of the anchor. | 04-07-2016 |
20160100940 | Valve Prosthesis - A heart valve prosthesis and delivery systems are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame includes a portion having a crimp that provides additional flexibility to the self-expanding frame in the collapsed configuration. | 04-14-2016 |
20160100941 | Inversion Delivery Device And Method For A Prosthesis - A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations. | 04-14-2016 |
20160100942 | FLEXIBLE CATHETER AND METHODS OF FORMING SAME - A delivery device for a collapsible prosthetic heart valve includes an outer shaft having a first end and a second end, an inner shaft disposed inside the outer shaft and longitudinally movable relative to the outer shaft, and a distal sheath coupled to the inner shaft and movable with the inner shaft to selectively cover and uncover a compartment for housing the valve. The outer shaft includes a plurality of disks each having at least two hinges to allow articulation of adjacent disks relative to one another, and at least one rib for coupling the adjacent disks to one another. | 04-14-2016 |
20160100944 | STENT-VALVES FOR VALVE REPLACEMENT AND ASSOCIATED METHODS AND SYSTEMS FOR SURGERY - Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided. | 04-14-2016 |
20160113762 | DEVICES, SYSTEMS AND METHODS FOR TISSUE APPROXIMATION, INCLUDING APPROXIMATING MITRAL VALVE LEAFLETS - Systems and methods for approximating tissue segments, such as mitral valve leaflets, on a minimally invasive basis. The system includes first and second approximation devices each including a magnetic component and an attachment mechanism. Each device is connected to a target tissue segment by the corresponding attachment mechanism. Upon deployment at a target site, the tissue approximation devices are magnetically attracted to one another, approximating the tissue segments and maintaining the tissue segments in the approximated state. | 04-28-2016 |
20160113763 | Aortic Valve Holder With Stent Protection And/Or Ability To Decrease Valve Profile - A valve holder is connectable to a prosthetic valve including a stent having a plurality of commissure posts. The valve includes a base, a plurality of legs extending from the base, and one of several mechanisms for deflecting the plurality of commissure posts radially inward so as to temporarily decrease the overall size of the prosthetic valve. | 04-28-2016 |
20160113765 | SYSTEMS AND METHODS FOR HEART VALVE THERAPY - Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks. This document also describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. In addition, this document describes prosthetic heart valve designs and techniques that reduce the risk of interference between the prosthetic valves and chordae tendineae. | 04-28-2016 |
20160113766 | SYSTEMS AND METHODS FOR HEART VALVE THERAPY - Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks. This document also describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. In addition, this document describes prosthetic heart valve designs and techniques that reduce the risk of interference between the prosthetic valves and chordae tendineae. | 04-28-2016 |
20160120644 | IMPLANTABLE PROSTHETIC VALVE WITH NON-LAMINAR FLOW - A valve prosthesis device and methods for deployment is disclosed. The device comprises an expandable support stent and a valve assembly comprising a flexible conduit having an inlet end and an outlet, made of pliant material attached to the support beams providing collapsible slack portions of the conduit at the outlet. Flow is allowed to pass through the valve prosthesis device from the inlet to the outlet, but reverse flow is prevented as the collapsible slack portions of the valve assembly collapse inwardly. The device is configured so that retrograde flow will be altered from laminar flow and directed towards the leaflets to effect closing. The device can be deployed in a native heart valve position using a deployment catheter advanced through a body lumen such as a blood vessel, including an aorta. | 05-05-2016 |
20160128829 | METHODS OF IMPLANTING A HEART VALVE AT AN AORTIC ANNULUS - An exemplary two-stage prosthetic heart valve system has a radially expandable base stent implanted within a native valve annulus. The two-stage heart valve system also has a valve component that is delivered to and mounted within the base stent in a separate or sequential operation after the base stent has been anchored within the annulus. The valve component in certain embodiments comprises a hybrid valve component that includes a conventional, non-expandable surgical valve that is modified to include an expandable coupling stent that can be expanded to engage the inner surface of the base stent, thereby anchoring the valve component to the base stent. In its expanded configuration, the outflow end portion base stent has tri-lobular shape that closely conforms to the shape of the aortic root and a support ring of the prosthetic valve that is mounted within the base stent. | 05-12-2016 |
20160128830 | METHODS FOR ENSURING SAFE AND RAPID DEPLOYMENT OF PROSTHETIC HEART VALVES - Methods of quickly and easily implanting a quick-connect heart valve prosthesis during a surgical procedure are provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement. | 05-12-2016 |
20160128831 | LOW PROFILE HEART VALVE DELIVERY SYSTEM AND METHOD - A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent. | 05-12-2016 |
20160135948 | DELIVERY SYSTEM FOR VASCULAR IMPLANT - A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state. | 05-19-2016 |
20160135951 | LOW PROFILE HEART VALVE AND DELIVERY SYSTEM - Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve. | 05-19-2016 |
20160135952 | HYPOTUBE SHAFT WITH ARTICULATION MECHANISM - A delivery device for a prosthetic heart valve includes a shaft, a sheath, and a pull wire. The shaft has a proximal end, a distal end, and a longitudinal axis. The sheath is attached to the shaft and is rotatable about an axis transverse to the longitudinal axis of the shaft. The pull wire is mechanically coupled to the sheath such that movement of the pull wire rotates the sheath relative to the shaft. The sheath may be in a first position relative to the shaft when a distal end of the pull wire is in a first position and may be in a second position when the distal end of the pull wire is in a second position. Deflection of the sheath relative to the shaft enables a prosthetic valve to be axially aligned with the native valve annulus for deployment. | 05-19-2016 |
20160135953 | Magnetically Coupled Cinching of a Loop Installed in a Valve Annulus - The diameter of an annulus in a patient (e.g., the mitral valve annulus) can be reduced using a tissue engaging member that is installed on the annulus and an actuator that is implanted into the patient's body. The tissue engaging member has anchors used to implant the tissue engaging member into the annulus, and a cinching loop runs through the tissue engaging member. The cinching loop terminates onto cinching wires. Preferably, tissue healing is used to enhance the bond between the tissue engaging member and the annulus. The actuator, which can be actuated from outside the patient's body, pulls the cinching wires in a proximal direction while holding the distal end of the cinching wires in close proximity to each other, so as to cause a reduction in the diameter of the cinching loop. This will cause a corresponding reduction in the diameter of the annulus. | 05-19-2016 |
20160143737 | Minimally Invasive Repair of Heart Valve Leaflets - A method of repairing a heart valve provides intravascular access for repair of a heart valve through a ventricular trans-septal approach. An external guide catheter can be inserted through a vein of a patient into the right ventricle via the right atrium. An internal guide catheter can be inserted through the external guide and can provide access to the septum for a puncture tool to create an opening through the septum to the left ventricle. The internal guide can then be advanced into the left ventricle and used to guide a deployment catheter that deploys a repair device onto the heart valve. | 05-26-2016 |
20160143740 | SIZE MEASURING TOOL FOR ARTIFICIAL ANNULUS - To provide an artificial annulus sizing tool capable of determining a suitable size for an artificial annulus to be implanted in a patient. | 05-26-2016 |
20160151063 | Stitching Device | 06-02-2016 |
20160151152 | METHODS AND APPARATUSES FOR DEPLOYING MINIMALLY-INVASIVE HEART VALVES | 06-02-2016 |
20160151156 | Material for Treatment of a Heart Valve, in Particular a Mitral Valve | 06-02-2016 |
20160157999 | SEQUENTIALLY DEPLOYED TRANSCATHETER MITRAL VALVE PROSTHESIS - A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab. | 06-09-2016 |
20160158008 | IMPLANTATION OF REPAIR CHORDS IN THE HEART - Apparatus is provided, including first and second longitudinal members coupled at respective first portions thereof to tissue surrounding the ventricle. The first portion of at least the first longitudinal member is coupled to a tissue anchor, and respective second portions of the first and second longitudinal members are coupled to respective first and second leaflets of a cardiac valve. The longitudinal members are arranged with respect to the tissue anchor and the portion of tissue surrounding the ventricle in a manner which facilitates adjustment of a degree of tension of the first and second longitudinal members to draw the first and second leaflets together. A longitudinal-member-coupling device is coupled to the first and second longitudinal members, and is advanceable toward a ventricular surface of the first and second leaflets, and responsively to draw together the first and second longitudinal members. Other applications are also described. | 06-09-2016 |
20160158009 | INTEGRATED HEART VALVE DELIVERY SYSTEM - Embodiments of the present disclosure provide a delivery apparatus for delivering a prosthetic heart valve to a native valve site via the human vasculature without the need for a separate introducer sheath. The delivery apparatus is particularly well-suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a stenotic aortic valve. | 06-09-2016 |
20160158497 | STEERABLE CATHETER WITH PULL WIRE - In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire. | 06-09-2016 |
20160166380 | Implant for Treatment of a Heart Valve, in Particular a Mitral Valve, Material Including Such an Implant, and Material for Insertion Thereof | 06-16-2016 |
20160166381 | DEVICES AND METHODS FOR RETRIEVABLE INTRA-ATRIAL IMPLANTS | 06-16-2016 |
20160184094 | MINIMALLY-INVASIVE HEART VALVE WITH CUSP POSITIONERS - A prosthetic heart valve having an internal support frame with a continuous, undulating leaflet frame defined therein. The leaflet frame has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. The leaflet frame may be cloth covered and flexible leaflets attached thereto form occluding surfaces of the valve. The support frame further includes three cusp positioners rigidly fixed with respect to the leaflet frame and located at the outflow end of the support frame intermediate each pair of adjacent commissure regions. The valve is desirably compressible so as to be delivered in a minimally invasive manner through a catheter to the site of implantation. Upon expulsion from catheter, the valve expands into contact with the surrounding native valve annulus and is anchored in place without the use of sutures. | 06-30-2016 |
20160184095 | REPLACEMENT HEART VALVE APPARATUS AND METHODS - Systems and methods for replacing a heart valve. An expansible helical anchor is formed as multiple coils to support a valve prosthesis. At least one of the coils is expandable to a second, larger diameter upon application force from within the anchor. A gap is defined between adjacent coils sufficient to prevent engagement by at least one of the adjacent coils with the native heart valve. An expansible heart valve prosthesis is provided and is configured to be delivered into the anchor and expanded inside the coils into engagement. This moves the coil from the first diameter to the second diameter while securing the anchor and prosthesis together. The system further includes a seal on the expansible heart valve prosthesis configured to engage the helical anchor and prevent blood leakage past the heart valve prosthesis after implantation of the heart valve prosthesis in the helical anchor. | 06-30-2016 |
20160193044 | HEART VALVE PROSTHESIS | 07-07-2016 |
20160193045 | SELF-ASSEMBLING PERCUTANEOUSLY IMPLANTABLE HEART VALVE | 07-07-2016 |
20160193046 | VALVULOPLASTY BALLOON AND VALVE STENT DEPLOYMENT CATHETER | 07-07-2016 |
20160193047 | Method and Apparatus Useful for Transcatheter Aortic Valve Implantation | 07-07-2016 |
20160199184 | CRIMPING ACCESSORY DEVICES AND METHODS OF USE | 07-14-2016 |
20160199185 | METHODS OF DEPLOYING A MITRAL HEART VALVE | 07-14-2016 |
20160250023 | INFUNDIBULAR REDUCER DEVICE DELIVERY SYSTEM AND RELATED METHODS | 09-01-2016 |
20160374793 | FILTER SYSTEM AND METHOD - A filter system, comprising an elongate filter body defining a lumen and having a proximal end and a distal end. A valve can be provided defining a lumen and having a reversibly sealable opening for unidirectional flow of a fluid through the lumen. The valve can be adjoined proximal the distal end of the elongate filter body, wherein the elongate filter body filters the unidirectional flow of the fluid passing through the lumen of the valve and the lumen of the elongate filter body. | 12-29-2016 |
20160374804 | TRANSCATHETER PROSTHETIC HEART VALVE POST-DILATATION REMODELING DEVICES AND METHODS - A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks. | 12-29-2016 |
20160374805 | RETAINERS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device | 12-29-2016 |
20160374811 | SELF-ALIGNING RADIOPAQUE RING - An intravascular device configured to be recaptured within a guide catheter has a ring located at the distal end of a delivery catheter. The ring has an outer diameter greater than that of the delivery catheter and a sloped guide surface near the outer edge of the ring to urge the ring and delivery catheter toward a radially centered position within the guide catheter. | 12-29-2016 |
20170231755 | Valve Delivery Tool | 08-17-2017 |
20170231760 | METHODS AND APPARATUS FOR ENGAGING A VALVE PROSTHESIS WITH TISSUE | 08-17-2017 |
20170231764 | TRANSCATHETER VALVE WITH PARAVALVULAR LEAK SEALING RING | 08-17-2017 |
20170231765 | APPARATUS FOR CONTROLLED HEART VALVE DELIVERY | 08-17-2017 |
20170231766 | TECHNIQUES FOR PROVIDING A REPLACEMENT VALVE AND TRANSSEPTAL COMMUNICATION | 08-17-2017 |
20180021132 | CATHETER SYSTEM FOR IMPLANTATION OF PROSTHETIC HEART VALVES | 01-25-2018 |
20180021134 | INDEPENDENT SYSTEM FOR TRICUSPID VALVE REPAIR | 01-25-2018 |
20190142582 | Straddle Annular Mitral Valve | 05-16-2019 |
20190142586 | STEERABLE ASSEMBLY FOR DELIVERING A PROSTHETIC HEART VALVE | 05-16-2019 |
20190142587 | SYSTEMS AND METHODS FOR PERCUTANEOUSLY SUPPORTING AND MANIPULATING A SEPTAL WALL | 05-16-2019 |
20190142589 | TISSUE GRASPING DEVICES AND RELATED METHODS | 05-16-2019 |
20190142590 | DEVICE FOR CARDIAC VALVE REPAIR AND METHOD OF IMPLANTING THE SAME | 05-16-2019 |
20190142591 | INTRODUCER SYSTEMS, DEVICES AND METHODS FOR HEART VALVE REDUCTIONS | 05-16-2019 |
20080288079 | Radial Head Implant and Related Instrument - A radial head implant including a head, a stem, and a locking mechanism, whereby the head laterally engages the stem, and an instrument for implanting and removing such implant is described. | 11-20-2008 |
20090024221 | MODULAR TOTAL ELBOW PROSTHESIS, HUMERAL COMPONENT AND ASSOCIATED KIT - An ulnar assembly for use with a humeral component to form an elbow prosthesis is provided. The ulnar assembly includes a first component including a portion thereof defining a stem for implantation in a cavity formed in the ulna. The first component defines a longitudinal axis thereof generally coincident with the longitudinal axis of the ulna. The ulnar assembly also includes a second component attached to the first component. The second component is attachable and removable from the first component along the longitudinal axis of the first component. One of the first component and the second component include an external taper. The other of the first component and the second component defines an internal taper therein adapted to receive the external taper. | 01-22-2009 |
20090036991 | Radial Head Replacement System - A radial head replacement system includes a radial head replacement, an apparatus for guiding the resection of a radial head, and a kit including bone plug and bone plug insertion instrument. The radial head replacement has a separate adjustable head portion that may be secured on an implanted stem such that the implanted radial head replacement smoothly interfaces with the capitellum of the humerus. In another form, the radial head replacement uses crossed bone screws that serve to more securely anchor the stem of the radial head replacement in the intramedullary canal of the radius. The resection guide includes a movable cutting guide which ensures a precise resection of the radial head and thereby allows for better positioning of the implanted radial head replacement. The bone plug limits the travel of bone cement beyond the area of affixation of the stem portion of a radial head replacement to the radius. | 02-05-2009 |
20090105839 | Artificial elbow joint - An artificial elbow joint including a humeral component made of metal and an ulnar component made of resins for replacing an elbow joint. The humeral component of this artificial elbow joint is configured by a substantially cylindrical trochlea and a stem extending from the trochlea that is inserted into the humeral; and the ulnar component is configured by a joint surface member which receives the trochlea of humeral component in a rotatable manner and a stem which extends from the joint surface member and is inserted into the ulna. The stem of the humeral component is curved gently downward overall so as to comply with the lordotic shape of the humeral, and the trochlea is turnable about the centerline of the stem. | 04-23-2009 |
20090281631 | ULNAR HEAD PROSTHESIS SYSTEM - An ulnar prosthesis assembly comprising a head formed with a curved surface extending between opposed ends and a stem. One of the ends of the head has an attachment bore defined therein. The attachment bore generally has a first diameter and includes an attachment groove thereabout with a second diameter greater than the first diameter to define at least one attachment shoulder. The stem has a stem body extending between a proximal end configured for implantation in a target bone and a distal end configured to be received in the attachment bore. The distal end has a locking flange extending radially therefrom. The locking flange defines a locking shoulder having a diameter greater than the first diameter such that upon receipt in the attachment bore, the locking shoulder engages the attachment shoulder. | 11-12-2009 |
20090281632 | ULNAR HEAD PROSTHESIS SYSTEM - An ulnar prosthesis assembly comprising a head formed with a curved surface extending between opposed ends and a stem. One of the ends of the head has an attachment bore defined therein. The attachment bore generally has a first diameter and includes an attachment groove thereabout with a second diameter greater than the first diameter to define at least one attachment shoulder. The stem has a stem body extending between a proximal end configured for implantation in a target bone and a distal end configured to be received in the attachment bore. The distal end has a locking flange extending radially therefrom. The locking flange defines a locking shoulder having a diameter greater than the first diameter such that upon receipt in the attachment bore, the locking shoulder engages the attachment shoulder. | 11-12-2009 |
20090312839 | LATERAL ELBOW PROSTHESIS - PROXIMAL RADIOULNAR JOINT - A proximal radioulnar joint (lateral elbow) prosthesis includes an ulnar brace member to be secured to the outer surface of the ulna bone. The ulnar brace member defines a bearing surface for supporting the radius. The prosthesis may also include a radial brace member which cooperates with the ulnar brace member. | 12-17-2009 |
20090312840 | PROSTHETIC ELBOW REPLACEMENT - A prosthetic elbow replacement includes a humeral component having a stem dimensioned to fit within a medullary canal of the humerus and having a yoke connected to the stem wherein the yoke terminates in spaced apart arms. A pivot pin is mounted between the arms for rotational movement with respect to the humeral component. The pivot pin has a transverse throughhole. There is an ulnar component having an ulnar stem including a distal end dimensioned to fit within a medullary canal of the ulna and an opposite proximal end dimensioned to fit within a first end opening of the throughhole. The ulnar component has a mounting cap dimensioned to fit within a second end opening of the throughhole. A fastener connects the ulnar stem and the mounting cap such the proximal end of the ulnar stem is positioned within the first end opening of the throughhole and the mounting cap is positioned within the second end opening of the throughhole. The pivot pin rotates to allow for flexion of the prosthetic elbow replacement, and also allows for axial rotation of the ulna component in the humeral component. | 12-17-2009 |
20100030339 | METHOD AND APPARATUS FOR ADJUSTING HEIGHT AND ANGLE FOR A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a radius. The prosthesis system includes a head component having a first connection portion that connects to a second connection portion and a collar component having the second connection portion and a third connection portion. The system also includes a stem component including a fourth connection portion that connects with the third connection portion, the stem component having a stem anchoring portion that connects to the radius. The collar component provides the modular geometry to the prosthesis without having to have an increased number of head components and stem components with variable lengths and angles. | 02-04-2010 |
20100087928 | Elbow Prosthesis - An elbow prosthesis constructed in accordance to one example of the present teachings can include a capitellar implant having an articulating head and a stem. The articulating head can have a first articulating surface positioned generally between a lateral side and a medial side. A passage can extend through the articulating head from the lateral side to the medial side. The articulating head can define a counterbore formed at the lateral side and that is concentric with the passage. According to other features, the elbow prosthesis can include a coronoid implant that has a body and a stem. The body can have a superior articulating surface that includes a central ridge and an anterior buttress. The central ridge can be configured to accommodate articulation with a trochlea in an implanted position. | 04-08-2010 |
20100222887 | Elbow Prosthesis - An elbow prosthesis constructed in accordance to one example of the present teachings can include a first stem structure that is operable to be positioned in a first bone of a joint. The first stem structure can include a first stem portion and a cage structure. The first stem portion may be operable to be positioned in the first bone. The cage structure can be formed generally between an inner sidewall and an outer surface. The stem portion can have opposing surfaces that define a disconnect formed entirely through the cage structure from the inner sidewall to the outer surface. A first bearing component can have an exterior cage opposing surface. The first bearing component can be selectively inserted into the cage structure from an insertion position to an installed position. A fastener can be threadably advanced into an engaged position with the cage structure to reduce a gap defined between the opposing surfaces of the disconnect while radially contracting the cage structure around the first bearing. | 09-02-2010 |
20100234960 | Articulating Implant System - An articulating implant system is provided for fixation to a bone. The articulating implant system includes a fixation component for fixation to the bone and an articulating member for articulating against bone or cartilage. Specifically, a modular ulnar implant is provided in accordance with the articulating implant system of the present invention wherein the fixation component is a stem for insertion into the intramedullary canal of the distal ulna and the articulating member is a head for articulating with the radial sigmoid notch. | 09-16-2010 |
20100241236 | Modular Radial Head Prosthesis - A prosthesis system for replacement of a head portion of a proximal radius can include an articulation component having a first connection portion. A first head component can have a second connection portion that connects to the first connection portion. A second head component can have a third connection portion that connects to the first connection portion. The second head component can have a distinct dimension from the first head component. A stem component can include a fourth connection portion that connects with either of the first or second head components. The stem component can have a stem anchoring portion that connects to the radius. | 09-23-2010 |
20100262251 | HIGH MODULUS CROSSLINKED POLYETHYLENE WITH REDUCED RESIDUAL FREE RADICAL CONCENTRATION PREPARED BELOW THE MELT - The present invention provides an irradiated crosslinked polyethylene containing reduced free radicals, preferably containing substantially no residual free radical. Disclosed is a process of making irradiated crosslinked polyethylene by irradiating the polyethylene in contact with a sensitizing environment at an elevated temperature that is below the melting point, in order to reduce the concentration of residual free radicals to an undetectable level. A process of making irradiated crosslinked polyethylene composition having reduced free radical content, preferably containing substantially no residual free radicals, by mechanically deforming the polyethylene at a temperature that is below the melting point of the polyethylene, optionally in a sensitizing environment, is also disclosed herein. | 10-14-2010 |
20100262252 | MODULAR PROSTHESIS AND USE THEREOF FOR REPLACING A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a proximal radius includes a monolithic stem component, a head component, and a locking mechanism formed by the stem and head components. The stem component defines a stem anchoring portion having a longitudinal axis and configured to couple to the proximal radius, and a dovetail-shaped first mounting portion on a first end face that extends in a first direction transverse to the longitudinal axis. The head component has a dovetail-shaped second mounting portion on a second end face opposite the first end face slidably engaged with the first mounting portion along the first direction. One of the first and second mounting portions intersects the longitudinal axis. The locking mechanism is formed at an interface between the stem and head components and is engaged through relative translational movement between the stem and head components. A related method is provided. | 10-14-2010 |
20110035016 | ALIGNABLE PROSTHESES DEVICE, SYSTEM AND METHOD - A prosthesis is provided for replacing a portion of a bone making up a joint. The prosthesis is adapted, intraoperatively, to optimize the anatomical alignment of the prosthesis in the joint. In particular, a jig is used to identify the axis of rotation of the joint intraoperatively and to align a portion of the prosthesis with the identified axis. The angle of the head of the prosthesis is adjusted to optimize contact with the appropriate corresponding portions of the joint, at which point the position of the head is fixed to prevent further rotation of the head relative to the remainder of the prosthesis. | 02-10-2011 |
20110125274 | ELBOW REPLACEMENT APPARATUS AND METHODS - Apparatus and methods for total elbow replacement are provided to allow a surgeon to intraoperatively select a linked or unlinked constraint by utilizing a connection located on the body of the ulnar and/or humeral stem. Additional modularity also allows the selection of a cemented or cementless stem as described herein. The modularity and adjustability provides a number of advantages. | 05-26-2011 |
20110125275 | PROSTHETIC CONDYLAR JOINTS WITH ARTICULATING BEARING SURFACES HAVING A TRANSLATING CONTACT POINT DURING ROTATION THEREOF - A prosthetic joint according to the present invention includes a first implant component for attachment to a first bone and a second implant component for attachment to a second bone. The first implant component has a condylar portion that includes first and second condylar bearing surfaces and similarly, the second implant component has bearing surfaces that receive and are complementary to the first and second condylar bearing surfaces. Each of the first and second condylar bearing surfaces and each of the bearing surfaces of the second implant component has a cross-section in a coronal plane that exhibits two different radii and a contact point is established between the first and second condylar bearing surfaces and the bearing surfaces of the second implant component. The bearing surfaces of the respective implant components are configured such that varus and valgus rotation of the first implant component relative to the second implant component causes the contact point to move outwardly. | 05-26-2011 |
20110125276 | MODULAR PROSTHESIS AND USE THEREOF FOR REPLACING A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a proximal radius includes a monolithic stem component, a head component, and a locking mechanism formed by the stem and head components. The stem component defines a stem anchoring portion having a longitudinal axis and configured to couple to the proximal radius, and a dovetail-shaped first mounting portion on a first end face that extends in a first direction transverse to the longitudinal axis. The head component has a dovetail-shaped second mounting portion on a second end face opposite the first end face slidably engaged with the first mounting portion along the first direction. One of the first and second mounting portions intersects the longitudinal axis. The locking mechanism is formed at an interface between the stem and head components and is engaged through relative translational movement between the stem and head components. A related method is provided. | 05-26-2011 |
20110144759 | MODULAR PROSTHESIS AND USE THEREOF FOR REPLACING A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a proximal radius includes a monolithic stem component, a head component, and a locking mechanism formed by the stem and head components. The stem component defines a stem anchoring portion having a longitudinal axis and configured to couple to the proximal radius, and a dovetail-shaped first mounting portion on a first end face that extends in a first direction transverse to the longitudinal axis. The head component has a dovetail-shaped second mounting portion on a second end face opposite the first end face slidably engaged with the first mounting portion along the first direction. One of the first and second mounting portions intersects the longitudinal axis. The locking mechanism is formed at an interface between the stem and head components and is engaged through relative translational movement between the stem and head components. A related method is provided. | 06-16-2011 |
20110166663 | LATERAL ELBOW PROSTHESIS - PROXIMAL RADIOULNAR JOINT - A proximal radioulnar joint (lateral elbow) prosthesis includes an ulnar brace member to be secured to the outer surface of the ulna bone. The ulnar brace member defines a bearing surface for supporting the radius. The prosthesis may also include a radial brace member which cooperates with the ulnar brace member. | 07-07-2011 |
20110172781 | ELBOW PROSTHESIS - An elbow prosthesis can include a capitellar implant that has an articulating head and a stem. The articulating head can have a first substantially hemispherical portion and a second portion that collectively extend between lateral and medial sides of the articulating head and are separated by a plane. The first and second portions can generally extend between the lateral and medial sides. The second portion can generally have an attachment lobe that extends on the lateral side and that defines a passage therethrough. The passage can extend at least partially on the second portion. | 07-14-2011 |
20110230972 | ELBOW RESURFACING PROSTHESIS - A method and apparatus for replacing a selected portion of the anatomy is described. In particular, a prosthesis can be provided to replace a portion of an articulating joint, such as an elbow. The apparatus can be modular for various reasons and each of the modular portions can include a different dimension to achieve a selected result. | 09-22-2011 |
20120059483 | ORTHOPEDIC INTERFACE DEVICE AND METHOD - An orthopedic joint implant component and implant component surface are disclosed. The implant component can have a resilient or compliant structure to distribute force loads. The implant component surface can be attached by one or more springs or other resilient or compliant elements to the remainder of the implant. Methods of using the component and component surface are also disclosed. | 03-08-2012 |
20120071985 | IMPLANT POSITIONING SYSTEMS AND ASSOCIATED METHODS - A system for securing a prosthesis in a bone includes a reference anchor for insertion into a cavity of a bone to define a reference point during prosthesis implantation, the reference anchor including a body having a mating feature and a gripping projection for engaging an inner surface of the bone cavity. The system also includes a stem having a terminal end adapted to mate with the engagement feature of the reference anchor such that the stem is disposed at a desired position relative to the reference point. | 03-22-2012 |
20120083892 | Modular Radial Head Prostheses - According to various embodiments, provided is a prosthesis system for replacement of a head portion of a proximal radius. The system can include a first polymeric articulation component having a first locking portion and a metal head component having a second locking portion. The second locking portion can mate with the first locking portion to form a first locking mechanism to initially couple the first articulation component to the head component. The head component can define a locking channel. The system can also include a stem component having a protrusion receivable in the locking channel. The protrusion can define a bore, and the stem component can be adapted to be coupled to the radius. The system can also include a fastener received through the locking channel and into the bore to provide a second locking mechanism that couples the head component to the stem component. | 04-05-2012 |
20120109323 | Modular Prosthesis And Use Thereof For Replacing A Radial Head - A tool provides for coupling a first prosthetic to a second prosthetic. The tool can include a first arm having a first concave bearing surface configured to apply a force in a first direction. The tool can also include a second arm having a hook shaped member. The hook shaped member can have a second concave bearing surface configured to apply a force in a second direction opposite the first direction. The first arm and the second arm can be generally parallel, and the first arm can be translatable with respect to the second arm. The tool can include a translation force mechanism, which can apply force to the first arm and the second arm so as to cause generally parallel translation of the first arm and second arm. | 05-03-2012 |
20120136450 | ELBOW JOINT PROSTHESIS AND METHOD FOR IMPLANTATION - A modular elbow prosthesis is disclosed, as well as a surgical approach and implantation technique, for using the prosthesis. The system is the first and only to allow for a, Biomechanically Anatomical, Nonconstrained, Compartmental (BANC) Elbow Arthroplasty. The modularity of the system allows it to be implanted as an unicompartmental or partial elbow replacement or a total elbow replacement. The modular elbow prosthesis for partial elbow replacement includes a cylindrical medial humeral component, a polyethylene ring thereon, and a semicircular medial ulnar component which mates with the polyethylene ring. Additionally, for total elbow replacement, the modular elbow prosthesis also includes a circular lateral humeral component, a polyethylene ring thereon, a semicircular lateral ulnar component, and a radial component. Implantation of the prosthesis is through a minimally invasive medial surgical approach with the aid of precision biomechanical guides. The application is well suited for canines, other quadrupeds, and people. | 05-31-2012 |
20120290099 | MINIMALLY INVASIVE SURGICAL TOOLS FOR HIP PROSTHESIS - Instrumentation for a modular prosthesis having a stem and a neck comprises a handle and an adaptor. The handle extends along an axis. The handle has a distal end and a proximal end. The proximal end has a blunt surface configured to be struck. The adaptor has a male end configured to mate inside the bore of the stem. The adaptor further has a surface configured to mate with the distal end of the handle. The adaptor is configured to have a medial portion and a lateral portion. The medial portion has a relief such that the adaptor is configured to disengage the stem when the adaptor is rotated relative the stem. | 11-15-2012 |
20130103158 | IMPLANTABLE ELBOW JOINT ASSEMBLY WITH SPHERICAL INTER-SUPPORT - A multi-component elbow joint assembly incorporated into reconditioned end surfaces established between an upper humerus bone and opposing lower radius and ulna bones. The assembly includes a first component anchored into the upper humerus reconditioned end surface and exhibits a first exposed support surface. A second component is anchored into the lower reconditioned bone end surface of at least one of the radius and ulna bones and exhibits a second exposed support surface. An intermediate component is supported in at least one of eccentric or rotational fashion between the first and second anchored components. | 04-25-2013 |
20130144395 | ELBOW ASSEMBLY FOR SURGICAL DEVICES - Surgical devices are disclosed herein that generally include an intracorporeal elbow joint to facilitate translational movement of an end effector while allowing a body portion of the surgical device and a trocar or working channel through which the device is inserted to be maintained in a fixed angular orientation relative to the patient. This allows a plurality of such devices to be used effectively with a single incision or access device. Such devices also generally provide end effector movement with six degrees of freedom, while maintaining a mechanical linkage between the user and the end effector and while mimicking and/or mirroring natural user movement. Various methods related to such devices are also disclosed. | 06-06-2013 |
20130178944 | Ulnar Head Implant - The present teachings provide an ulnar head implant. The implant can include a head component adapted to articulate with a portion of the anatomy. The head component can define a coupling bore through a surface. The implant can also include a stem component having a base and a post that extends from the base for insertion into a prepared portion of an anatomy. The base can include a coupling feature. The implant can include an intermediate component receivable within the coupling bore and couplable to the coupling feature to couple the head component to the stem component. | 07-11-2013 |
20130268082 | CANINE ELBOW REPAIR AND INSTRUMENTATION - Instrumentation and assembly for arthroscopic elbow surgery which includes a humeral component. The humeral component is installed in a trough formed in the humeral condyle. The trough may be formed by using a plurality of drill pins and a plurality of corresponding cutters (and optionally a template). The two drill pins are passed through the template and drilled into the humerus, and cutters are advanced over the corresponding drill pins to form the trough. The humeral component may be employed in conjunction with an ulnar implant. | 10-10-2013 |
20140074246 | RADIAL HEAD PROSTHESIS WITH FLOATING ARTICULAR MEMBER - System, including apparatus, methods, and kits, for replacement of the proximal end of a radial bone with a prosthesis having a floating articular member. The prosthesis may include a head portion connected or connectable to a stem portion. While the stem portion remains operatively connected to the head portion, the head portion and/or an articular member thereof may be permitted to float in position relative to the stem portion. The head portion/articular member may float transversely (e.g., translationally) and/or rotationally with respect to the stem portion. The articular member may articulate with a humeral bone or both a humeral bone and an ulnar bone. In some embodiments, the head portion may include a fixed member for articulation with an ulnar bone and a floating member for articulation with a humeral bone. | 03-13-2014 |
20140277524 | RADIAL HEAD IMPLANT - A radial head prosthesis for implantation in a distal radius. The implant includes a head portion and a stem portion. The stem portion has a cylindrical shaft and tapered tip. The head portion includes a recess for engagement with the stem portion. The head portion includes a first bearing surface for articulation with a humerus, and a second bearing surface for articulation with an ulna. The second bearing surface includes at least one concave and one convex portion immediately adjacent one another. | 09-18-2014 |
20140324175 | ELBOW PROSTHESIS - A joint prosthesis is provided and may include first and second stem structures and first and second bearing members. The first stem structure may include a generally U-shaped portion having first and second legs. The second stem structure may include first and second bearing surfaces. The first bearing member may be removably coupled to the first leg and may include a first laterally facing bearing surface rotatably contacting the first bearing surface. The second bearing member may be removably coupled to the second leg and may include a second laterally facing bearing surface rotatably contacting the second bearing surface. The first laterally facing bearing surface may be disposed between the first leg and a first lateral side of the second stem. The second laterally facing bearing surface may be disposed between the second leg and a second lateral side of the second stem. The second lateral side may oppose the first lateral side. | 10-30-2014 |
20150073561 | MODULAR RADIAL HEAD PROSTHESIS - A method for implanting a prosthesis system for replacement of a head portion of a proximal radius includes determining a distance between a proximal radius and a humerus. The method also includes selecting one of a first head component or a second head component based on the determination. The first and second head components have unique heights. The method further includes connecting the selected first or second head component to an articulation component and connecting a stem component to the selected first or second head component. | 03-12-2015 |
20150289982 | ELBOW PROSTHESIS - An elbow prosthesis includes a stem structure and an articulating component. The stem structure is operable to be positioned in a bone of a joint and includes a stem portion and a C-shaped body portion. The stem portion is operable to be positioned in the bone. The C-shaped body portion includes a first articulating surface bound by a medial wall and a lateral wall. The medial and lateral walls are separated by a first distance. The articulating component includes a second articulating surface positioned between a medial side surface and a lateral side surface. The medial and lateral side surfaces are separated by a second distance that is less than the first distance. The second articulating surface is configured to slidably communicate in a medial/lateral direction along the first articulating surface of the C-shaped body portion. | 10-15-2015 |
20150297351 | CANINE ELBOW REPAIR AND INSTRUMENTATION - Instrumentation and assembly for arthroscopic elbow surgery which includes a humeral component. The humeral component is installed in a trough formed in the humeral condyle. The trough may be formed by using a plurality of drill pins and a plurality of corresponding cutters (and optionally a template). The two drill pins are passed through the template and drilled into the humerus, and cutters are advanced over the corresponding drill pins to form the trough. The humeral component may be employed in conjunction with an ulnar implant. | 10-22-2015 |
20160022425 | RADIAL HEAD PROSTHESIS WITH FLOATING ARTICULAR MEMBER - System, including apparatus, methods, and kits, for replacement of the proximal end of a radial bone with a prosthesis having a floating articular member. The prosthesis may include a head portion connected or connectable to a stem portion. While the stem portion remains operatively connected to the head portion, the head portion and/or an articular member thereof may be permitted to float in position relative to the stem portion. The head portion/articular member may float transversely (e.g., translationally) and/or rotationally with respect to the stem portion. The articular member may articulate with a humeral bone or both a humeral bone and an ulnar bone. In some embodiments, the head portion may include a fixed member for articulation with an ulnar bone and a floating member for articulation with a humeral bone. | 01-28-2016 |
20160051365 | RADIAL HEAD TRIALS - A radial head trial device for replacement of a proximal radial head includes a stem component having a center longitudinal axis extending between a proximal end and a distal end, a head component axially and removably attachable to the stem component, wherein the head component is interchangeable with a selection of other head components each axially and removably attachable to the stem component, an anti-rotation feature, and a recess, wherein the anti-rotation feature is structured to be received in the recess to prohibit rotation of the head component relative to the stem component. | 02-25-2016 |
20180021142 | METHOD OF STABILIZING A PATIENT'S ULNOHUMERAL JOINT | 01-25-2018 |