Class / Patent application number | Description | Number of patent applications / Date published |
600008000 | Seeds | 61 |
20080234532 | FIDUCIAL MARKER - A fiducial marker which is visible to a wide range of imaging techniques, comprises a radiopaque material, such as barium sulphate or a metal wire, encapsulated in a biocompatible polymeric material, for example a polyaryletherketone such as polyetheretherketone. | 09-25-2008 |
20080287729 | INTERSTITIAL MARKER AND METHOD FOR CREATION THEREOF - An interstitial marker for localization of organs, biopsy sites, tumors or tumor beds, is comprised of a fluid marker material which is visible under at least one imaging modality. The fluid marker material is injected at the desired location to create a marker having a desired size and configuration. The configuration includes combinations of straight and curved lines, spheres and blank spaces. The fluid marker material includes a high density metal such as bismuth, gold, or iridium suspended in a liquid, in colloidal form or made into a solution. | 11-20-2008 |
20090099402 | IMPLANTS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION - In an embodiment a therapeutic member includes a solitary radioactive seed. The seed includes a metallic housing with radioactive material contained within the metallic housing. The metallic housing has a first longitudinal end and a second longitudinal end and a longitudinal length between the first and second longitudinal ends. A polymeric material is molded to completely and monolithically encapsulate the metallic housing of the solitary radioactive seed. The implantable therapeutic member is adapted to be implanted into patient tissue using a hollow needle. A portion of the molded polymeric material extends from one of the first and second longitudinal ends of the metallic housing to reduce a tendency of the seed to migrate and rotate within a patient's body after implantation of the member. The portion of the molded polymeric material, that extends from one of the first and second longitudinal ends of the metallic housing, causes the implantable therapeutic member to have a longitudinal length that is greater than the longitudinal length of the metallic housing. | 04-16-2009 |
20090131734 | Implantable medical marker and methods of preparation thereof - An implantable medical marker, the marker comprising a marker body adapted for insertion via a needle and adapted to define a volume with a smallest dimension larger than an inner diameter of the needle; and a radiation source—characterized by gamma emissions sufficient to exit the human body. | 05-21-2009 |
20090131735 | Implant Comprising Radioactive Seeds - The present disclosure relates to an implant comprising at least two sheets of a biocompatible material, and at least one radioactive seed disposed between said sheets of material. The disclosure also relates to a method for treating a patient, comprising fixing to the tissue of the patient at least one implant comprising at least two sheets of a biocompatible material, and at least one radioactive seed disposed between said sheets of material. | 05-21-2009 |
20090149692 | IMPLANTS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION - In an embodiment a therapeutic member includes a single radioactive seed and is adapted to be implanted into patient tissue using a hollow needle. The seed includes a metallic housing with radioactive material contained within the metallic housing. A polymeric bio-adherent and/or bio-adhesive material surrounds at least a portion the housing of the single radioactive seed. The polymeric bio-adherent and/or bio-adhesive material reduces a tendency of the member to migrate and rotate within a patient's body after implantation of the member. | 06-11-2009 |
20090203953 | THERAPEUTIC MEMBER INCLUDING A RAIL TO RESIST MOVEMENT WITHIN A NEEDLE USED IN BRACHYTHERAPY AND OTHER RADIATION THERAPY - A therapeutic member for use in brachytherapy deliverable to an implant site by way of a needle comprises a single radioactive source encapsulated by a bio-absorbable material having an outer surface including one or more ribs encircling the single radioactive source, a leading edge endcap rib and a trailing edge endcap rib. The one or more ribs reduces a tendency of the member to migrate and rotate within a patient's body after implantation. The encapsulating material further includes a first rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, and a second rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, the second rail arranged in a plane substantially perpendicular to a plane in which the first rail is arranged. | 08-13-2009 |
20090216065 | Radiation Containing Seeds and Method for High Visibility Magnetic Imaging - A radioactive seed and method for making a radioactive seed with selective magnetic imaging characteristics are provided. The seed comprises a housing which may include a metal shell for at least partially enclosing a radioactive material. The shell encloses a rod having a nickel layer with a phosphorous content, wherein the phosphorous content comprises a level of phosphorous sufficient, when the seed is implanted in tissue, to provide a defined magnetic resonance signature of the seed while substantially eliminating gross artifacts in the magnetic resonance image. | 08-27-2009 |
20090247807 | RADIOTHERAPY DEVICE AND METHOD - A radioactive implant for brachytherapy includes a composite radioactive source having at least two different types of radionuclides. | 10-01-2009 |
20090264696 | EXPANDABLE BRACHYTHERAPY DEVICE - A brachytherapy device for the provision of brachytherapy is disclosed. The brachytherapy device has at least one source lumen located outside a movable surface of the device. The source lumen may be secured to the movable outer surface in a manner whereby relative movement of the source lumen relative to the movable outer surface is permitted. The brachytherapy device is inserted into a body cavity. After insertion, the movable surface is moved to position the at least one source lumen closer to the tissue boundary of the cavity. One or more sources of radiation are then placed within the at least one source lumen to provide a customizable treatment. Also disclosed are methods for providing brachytherapy via body cavities. | 10-22-2009 |
20090275793 | BRACHYTHERAPY DEVICES AND RELATED METHODS AND COMPUTER PROGRAM PRODUCTS - Methods of forming a low-dose-rate (LDR) brachytherapy device include depositing a solution comprising a soluble form of a radioactive material on a substrate. A water-insoluble form of the radioactive material is formed on the substrate by chemical precipitation and/or thermal decomposition. | 11-05-2009 |
20090318746 | Lubricious echogenic coatings - Medical devices can include a lubricious echogenic coating that is slippery when wet and provides visibility during ultrasonic imaging. | 12-24-2009 |
20100056843 | Brachytherapy Seed With Fast Dissolving Matrix for Optimal Delivery of Radionuclides To Cancer Tissue - A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved or broken so as to release the microspheres. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method. | 03-04-2010 |
20100056844 | BRACHYTHERAPY SEED WITH FAST DISSOLVING MATRIX FOR OPTIMAL DELIVERY OF RADIONUCLIDES TO CANCER TISSUE - A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta- or alpha-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved so as to release the microspheres from the polymer matrix. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding or minimizing undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method. | 03-04-2010 |
20100099940 | Thulium-containing low dose rate brachytherapy seed - A low dose rate brachytherapy seed having activity in the range between 0.5 and 10 millicurie, preferably less than 3 millicurie, comprising thulium-170 placed within a casing and at least one layer of a radiation emission modifying metal, said layer being provided either internally within the casing or on the outer surface thereof. The radiation emission modifying metal is preferably gold. | 04-22-2010 |
20100121130 | DELIVERY SYSTEM AND METHOD FOR INTERSTITIAL RADIATION THERAPY - A prescription method of treating tissue comprises the steps of accepting a prescription tissue treatment plan for the tissue to be treated, positioning seeds relative to each other per the prescription tissue treatment plan such that the positions of seeds relative to each other is only established by the prescription tissue treatment plan, and creating a treatment strand by heating and cooling a material to position the plurality of treatment seeds in the material. The prescription tissue treatment plan specifies a number and a spacing of the seeds to be provided in the treatment strand, the spacing of the treatment seeds being unrestricted by any use of spacers and independently set by and according to the prescription tissue treatment plan. | 05-13-2010 |
20100261946 | FLEXIBLE AND/OR ELASTIC BRACHYTHERAPY SEED OR STRAND - A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible. | 10-14-2010 |
20100298622 | APPARATUSES AND TECHNIQUES FOR BIOACTIVE DRUG DELIVERY IN THE PROSTATE GLAND - Methods and apparatuses for the delivery of bioactive substances into the prostate. The present invention encompasses the release of bioactive substances into the prostate of a patient. Preferably, the present invention employs either a sustained-release or depot formulation of the bioactive substance to release the substance over an extended period of time. In particularly-preferred embodiments, the apparatuses of the present invention release of anti-inflammatory agents into the prostate. The anti-inflammatory agents preferably reduce the inflammation that is associated with brachytherapy and other conditions of the prostate. In particular, corticosteroid anti-inflammatory agents are employed in the context of the present invention. | 11-25-2010 |
20100324353 | ADHESIVE-STIFFENED BRACHYTHERAPY STRAND - A stranded brachytherapy product and methods of forming a stranded brachytherapy product. The methods includes the step of applying an adhesive to a carrier containing at least one brachytherapy seed so as to, upon curing of the adhesive, impart substantial rigidity to the carrier. Alternatively, the adhesive may be selectively applied so as to provide a deflectable brachytherapy product. | 12-23-2010 |
20110054235 | PACKAGING SYSTEM FOR BRACHYTHERAPY IMPLANT AND CUTTING THEREOF - The present disclosure relates to a thermo formed tray having an upper half and a lower half. The upper half and the lower half define a closed configuration when the upper half and the lower half are substantially adjacent one another and an open configuration when the upper half and the lower half are substantially apart from one another. A predetermined area is provided in at least one of the upper half and the lower half for containing a product in the closed configuration, the product having at least one radioactive seed held in a predetermined seed configuration. At least one cutter guide is contained in the thermo formed tray. | 03-03-2011 |
20110118532 | Brachytherapy seed - A radiopaque brachytherapy seed for implantation into a subject includes a biocompatible component, a therapeutically active component including a non-radioactive drug, and a radiopaque marker. The biocompatible component is (a) physically associated with a therapeutically active component and (b) in contact with the radiopaque marker. The brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge). | 05-19-2011 |
20110166410 | METHOD AND SYSTEM FOR BRACHYTHERAPY - A brachytherapy system for a target region ( | 07-07-2011 |
20120016176 | IMPLANTS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION - A therapeutic strand implant, for use in brachytherapy and deliverable to an implant site by way of a needle, includes a plurality of radioactive sources, and a polymeric material molded to encapsulate the radioactive sources. A space is defined by the polymeric material between each adjacent pair of the radioactive sources. A plurality of protrusions is defined by an outer surface of the encapsulating polymeric material. | 01-19-2012 |
20120065454 | TETHERED AND/OR VISUALLY CODED BRACHYTHERAPY DEVICES AND RELATED METHODS - Bracytherapy devices include a respective tether attached to a proximal end portion of the strands. The tether can be color-coded to match a color associated with the corresponding strand. | 03-15-2012 |
20120108882 | Brachytherapy Devices and Related Methods Providing Bioaborbability and/or Asymmetric Irradiation - A brachytherapy device includes a sealed housing having a radioactive material therein, and at least one shielding member extending away from the housing and configured to provide radiation shielding on at least one side of the housing. | 05-03-2012 |
20120123189 | ONCOLOGY THERAPIES EMPLOYING RADIOACTIVE SEEDS - An oncology therapy method comprises implanting a radioactive seed ( | 05-17-2012 |
20120142993 | Method for large scale production of cesium-131 with low cesium-132 content - The present invention provides a method for large scale production of cesium-131 (Cs-131) with low cesium-132 (Cs-132) content, where the Cs-131 is produced via barium-131 (Ba-131) decay. Uses of the Cs-131 produced by the method include cancer research and treatment, such as for use in brachytherapy. Cesium-131 is particularly useful in the treatment of faster growing tumors. | 06-07-2012 |
20120253100 | BRACED BRACHYTHERAPY NEEDLE - Braces to reduce bending of a brachytherapy needle during insertion into a patient, as well as methods of using the needle braces and kits useful therefor. | 10-04-2012 |
20120259153 | DELIVERY SYSTEMS FOR BRACHYTHERAPY, AND ASSOCIATED METHODS - Delivery systems adapted for implementation during a brachytherapy procedure are provided. The delivery system includes a plurality of brachytherapy seeds and a plurality of spacers. Each spacer is formed of a matrix material carrying a plurality of microparticles and/or nanoparticles. The microparticles and/or nanoparticles carry an agent and are biodegradable and/or biocompatible. The brachytherapy seeds and the spacers are configured to be delivered to a target site. Associated methods are also provided. | 10-11-2012 |
20120277519 | Apparatus and Method to shield Radiation Needles - According to one general aspect there is a needle package apparatus that comprises a top portion and a bottom portion; a plurality of needle slots exact distance apart that allows to place a plurality of needles that contain radioactive seeds; a cylindrical coil that is inserted to the plurality of needle slots to hold said plurality of needles, wherein said cylindrical coil prevents the leakage of the radiation from the radioactive seeds; a set of hinges located at the end of said needle package within the outer most said plurality of needle slots; wherein the hinges can be bend to change the angle of said top portion of said needle package by a medical personnel to create a stand; and a single end enclosure located at the distal end of said cylindrical coil to provide an enclosed cylinder. | 11-01-2012 |
20130035537 | ROBOTIC SYSTEMS AND METHODS FOR TREATING TISSUE - A method of manipulating an elongate member in at least two degrees of freedom includes holding an elongate member between two rotary members that define respective rotational axes, the elongate member having a flexible proximal portion, a distal rigid needle attached to the proximal portion, and an operative element for delivering energy, the needle having a distal port, actuating at least one of the rotary members in a rotational direction about its rotational axis to generate a corresponding linear motion of the elongate member along a longitudinal axis of the elongate member, and actuating at least one of the rotary members in a linear direction along its rotational axis to generate a corresponding rotational motion of the elongate member about the longitudinal axis of the elongate member. | 02-07-2013 |
20130046128 | Radiotherapy Delivery Cannula With Visual Confirmation Window - A radiotherapy delivery device is provided comprising an elongated applicator having a proximal end and a distal end having a tip. The distal end is adapted to be introduced into a body including a treatment zone to be located adjacent a target tissue. A radiotherapy emitter is provided that is moveable between the proximal end of the applicator and the treatment zone of the applicator. The applicator includes a window to permit visual confirmation of the location of the radiation emitter and the treatment zone. | 02-21-2013 |
20130102832 | BRACHYTHERAPY DEVICES AND RELATED METHODS HAVING MICROENCAPSULATED BRACHYTHERAPY MATERIALS - A brachytherapy device includes a bioabsorbable support and a plurality of microcapsules on the support. Each of the plurality of the microcapsules includes a plurality of microspheres and a bioabsorbable microcapsule wall that encloses the plurality of microspheres. The plurality of microspheres includes radiation-emitting microspheres comprising a radioactive material, radio-opaque microspheres comprising a radio-opaque material or a combination thereof. | 04-25-2013 |
20130131434 | DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS AND METHODS THEREOF IN THE TREATMENT OF TUMORS - Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors. | 05-23-2013 |
20130190549 | POINT OF CARE RADIOACTIVE MATERIAL STRANDING SYSTEMS - A point-of-care seed stranding device for automating assembly of brachytherapy seed strands for implantation in patients. The device includes a number of features to reduce the potential for mistakes by the user, as well as to reduce the potential for damaging the radioactive seeds during the stranding process. Tactile feedback may be provided to prevent exertion of too much force in the packing step of the stranding process, as well as to indicate that the seed and/or strand cartridges are empty and need to be replaced. The device may also include a mechanism for holding seeds or spacers in place to allow automated packing of seeds or spacers having corresponding geometries. The device may also be provided with a seed counter which can be employed to preset the number of seeds in a strand and which disables the device from dispensing or packing additional seeds once the preset number of seeds has been packed into the strand. Also, methods for automated assembly of seed strands including the steps of setting the number of seeds, dispensing seeds and spacers, packing seeds and spacers and transferring assembled strands to another device. | 07-25-2013 |
20130204072 | METHOD AND APPARATUS FOR BRACHYTHERAPY FEATURING TRACKING VIA SHAPE-SENSING - A brachytherapy method and apparatus include implanting an applicator having at least one radiation source or seed receiving channel ( | 08-08-2013 |
20130217952 | OPHTHALMIC ORBITAL SURGERY APPARATUS AND METHOD AND IMAGE-GUIDED NAVIGATION SYSTEM - A flexible endoscope for ophthalmic orbital surgery includes a flexible probe housing having a proximal end, a distal end and a lumen extending between the proximal end and the distal end. The endoscope also includes an image fiber disposed in the lumen that communicates image information from the distal end of the flexible probe, a purge fluid/gas port disposed at the proximal end of the flexible probe that accepts purge fluid/gas and a purge fluid/gas conduit disposed in the lumen and in fluid communication with the purge fluid/gas port. The fluid/gas conduit delivers purge fluid/gas to the distal end of the endoscope. The endoscope also includes an access conduit disposed in the lumen that receives one of an ablation instrument, a coagulating instrument and a medication delivery instrument. | 08-22-2013 |
20130253255 | Brachytherapy Seed, Methodology and Calculating Dose of Brachytherapy and Method of Treatment - The invention provides for a brachy-therapy seed, wherein the seed includes at least two disparate radionuclides of a chemical element, the radionuclides encapsulated to form a brachytherapy seed and wherein the combination of the disparate radionuclides of the chemical element is used to augment dosimetric parameters and radiobiological characteristics of the brachytherapy seed. The invention also provides a method of manufacturing a brachytherapy seed that includes the steps of bombarding elemental silver with high energy protons produced by a cyclotron to obtain a target of 100 Pd and 103 Pd; dissolving and passing the target through a column of resin beads; placing at least one resin bead having adsorbed 100 Pd and 103 Pd into a titanium tube that is closed at one end; inserting a radiopaque member into the titanium tube; and closing the opposite end of the titanium tube. | 09-26-2013 |
20130338423 | APPARATUS FOR LOADING DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS - A device for loading and customizing brachytherapy carriers based on the principles of optimizing a more precise and predictable dosimetry, and adaptable to the geometric challenges of a tumor bed in a real-time setting. The present invention relates to a specialized loading device designed to enable a medical team to create a radionuclide carrier for each patient and tumor reliably, reproducibly and efficiently. | 12-19-2013 |
20140018607 | SYSTEM AND METHOD FOR IMAGE-GUIDED THERAPY PLANNING AND PROCEDURE - A method for generating a treatment plan for therapy comprising obtaining image data representing a tissue, determining a therapy dose map comprising dose values for a plurality of dose points based on the image data, forming a desired dose value vector comprising the dose values for the plurality of dose points, determining a one or more potential therapy locations based on the image data, determining a therapy dose map equation for each of the plurality of dose points based on the one or more potential therapy locations, forming a matrix based on the therapy dose map equations for the each dose points, determining an inverse of the matrix and determining the treatment plan by multiplying the desired dose value vector by the inverse of the matrix. | 01-16-2014 |
20140179979 | THERAPEUTIC AGENT APPLICATORS AND METHODS OF USING THE SAME - The present application relates to applicators and methods for administering therapeutic agents to cancerous tissue. The applicators can be used to deliver radiation and additional therapeutic agents to cancerous tissue located in a subject. | 06-26-2014 |
20140206926 | METHODS FOR OPTIMIZING AND EVALUATING DOSE DISTRIBUTIONS IN BRACHYTHERPAY - Methods and systems are disclosed for radiation therapy treatment planning. In one embodiment, a radiation therapy treatment planning method is disclosed for adjusting a dose distribution of a target anatomical portion. The method includes displaying an image of an implanted volume and a set of catheters displayed as implanted in the anatomical portion. The method also includes determining to adjust the dose distribution to the implanted volume for delivering via the catheters. The method also includes receiving, at a processor, a selection of a dose distribution parameter affecting the strength of the dose distribution and adjusting, based on the received parameter, a dwell weight of the radiation dose at each dose position in the set of catheters, wherein the adjusted dwell weight adjusts the dose distribution relative to a center region of the implanted volume for moving the distribution to or from an outer circumference of the target anatomical portion. | 07-24-2014 |
20140275715 | DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS AND METHODS THEREOF IN THE TREATMENT OF TUMORS - Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors. | 09-18-2014 |
20140296611 | Brachytherapy Radiation Protective Shield and Method for Protecting Against Radiation - A lightweight, portable, interchangeable and effective shield that will protect from radiation during the radioactive seed insertion and positioning in brachytherapy. The shield is attached to the matrix used to position and guide the needles with the radioactive seeds. The shield minimizes the radiation exposure as much as reasonably possible because any amount of radiation exposure carries a risk to the exposed individual. | 10-02-2014 |
20140296612 | Brachytherapy Assist Device - A lightweight, portable, interchangeable and effective overlay plate that will increase the efficiency of brachytherapy radiation treatment and reduce the duration of the radiation exposure during the radioactive seed insertion and positioning in brachytherapy. The overlay plate has a limited number of apertures specific to the treatment of a particular patient and is attached to the matrix used to position and guide the needles with the radioactive seeds. The apertures of the overlay plate may further be truncated-cone-shaped, with the narrow ends aligned with corresponding apertures in the matrix and the flared ends facing the user. The overlay plate minimizes the radiation exposure as much as reasonably possible because any amount of radiation exposure carries a risk to the exposed individual, and the overlay plate may also be manufactured from radiation-protective material to further minimize the radiation exposure. | 10-02-2014 |
20140303423 | MEDICAL APPARATUS FOR DISPLAYING THE CATHETER PLACEMENT POSITION - The invention provides for a medical apparatus ( | 10-09-2014 |
20140316187 | DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS AND METHODS THEREOF IN THE TREATMENT OF TUMORS - Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors. | 10-23-2014 |
20140323795 | BENDABLE, SHIELDING BRACHYTHERAPY NEEDLE HOLDER PROVIDING ONE-HANDED ACCESS - A brachytherapy needle holder includes a needle card holding one or more brachytherapy needles preloaded with one or more brachytherapy seeds, wherein the needle holder includes a scored needle card shield that may be bent at the score so that the needle card may stand up on its own, providing one-handed access. A brachytherapy needle holder includes a needle card holding one or more brachytherapy needles preloaded with one or more brachytherapy seeds, wherein the needle holder further includes a needle card shield that provides one or more of rigidity and shielding from radiation for one or more of a physician and other medical personnel. | 10-30-2014 |
20140343348 | METHODS AND DEVICES FOR DIAGNOSING, MONITORING, OR TREATING MEDICAL CONDITIONS THROUGH AN OPENING THROUGH AN AIRWAY WALL - Methods and devices for diagnosing, monitoring, and/or treating tissue through an opening or port through an airway wall. A passageway is created extending from the airway to the target tissue. The passageway provides local access to the target tissue for treatment instruments and for delivering agents. | 11-20-2014 |
20140350325 | AFTERLOADING DEVICE, AND USE THEREOF - An afterloading device for effectuating a brachytherapy treatment, comprising a first elongated flexible transport element, arranged to maneuver a radiation source between a storage position inside the afterloading device and a treatment position outside the afterloading device, the afterloading device further comprising a second elongated flexible transport element, having at least one transducer, the second transport element being arranged to move the at least one transducer between a first transducer position and a second transducer position. | 11-27-2014 |
20140350326 | Brachytherapy Seed with Fast Dissolving Matrix for Optimal Delivery of Radionuclides to Cancer Tissue - A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta- or alpha-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved so as to release the microspheres from the polymer matrix. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding or minimizing undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method. | 11-27-2014 |
20140378739 | RADIOACTIVE THERAPEUTIC DEVICE WITH FIXATION - Devices and techniques for permanent application of radioactive sources in the field of brachytherapy are described. In an embodiment, an implantable device for radiation therapy of pathological tissues directed toward the administration of radiation to tissue adjacent a cavity wall or surgical excision. The device may include an insertable member, such as a substantially cylindrical member, having at least two ends, a central section positioned between the ends, and a fixation element to retain the implantable device implanted in tissue at a desired position. The device may further include a radioactive source at least partially positioned within the insertable member and that is disposed to deliver radiation to a desired area. | 12-25-2014 |
20150031935 | DELIVERY APPLICATOR FOR RADIOACTIVE STAPLES FOR BRACHYTHERAPY MEDICAL TREATMENT - An instrument used for brachytherapy delivery in the treatment of cancer by radiation therapy including a handle having first and second handle actuators; an end effector; and an instrument shaft that connects the handle with the end effector. The end effector has first and second adjacent disposed staple cartridges that each retain a set of staples. The first mechanism is for holding standard staples in a first array, and dispensing the standard staples under control of the corresponding first handle actuator. The second mechanism is for holding radioactive source staples in a second array, and dispensing said radioactive source staples under control of the corresponding second handle actuator. The actuating device is removably attachable to an actuator arm on a proximal end. A staple applicator cartridge holder is attached to the actuator arm on a distal end. The staple applicator cartridge is mountable in the holder and having a plurality of slots for mounting of radioactive source staples therein. An anvil therein crimps the staples. | 01-29-2015 |
20150057487 | DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS AND METHODS THEREOF IN THE TREATMENT OF TUMORS - Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors. | 02-26-2015 |
20150306421 | EXPANDABLE BRACHYTHERAPY DEVICE - A method for brachytherapy in a lumpectomy cavity of a breast including, positioning a distal end of a brachytherapy device within the cavity, expanding an expandable surface portion located between proximal and distal ends of the device within the cavity, the source lumen tubes defining a curved configuration within the cavity; and positioning a source of radiation sequentially within one or more source lumens of the source lumen tubes according to a brachytherapy treatment plan. The device includes an inner tube, and a plurality of source lumen tubes located around the inner tube and including distal ends secured together with the inner tube at the distal end disposed within the body cavity, the source lumen tubes comprising proximal portions sufficiently long to extend outside the breast. | 10-29-2015 |
20150320895 | RADIOACTIVE NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME - In one aspect, radioactive nanoparticles are described herein. In some embodiments, a radioactive nanoparticle described herein comprises a metal nanoparticle core, an outer metal shell disposed over the metal nanoparticle core, and a metallic radioisotope disposed within the metal nanoparticle core or within the outer metal shell. In some cases, the radioactive nanoparticle has a size of about 30-500 nm in three dimensions. In addition, in some embodiments, the radioactive nanoparticle further comprises an inner metal shell disposed between the metal nanoparticle core and the outer metal shell. The metal nanoparticle core, outer metal shell, and inner metal shell of the radioactive nanoparticle can have various metallic compositions. | 11-12-2015 |
20150321024 | DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS AND METHODS THEREOF IN THE TREATMENT OF TUMORS - Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors. | 11-12-2015 |
20150375011 | Brachytherapy Seed Insertion and Fixation System - Brachytherapy seed insertion and fixation devices and systems to decrease implanted brachytherapy seed migration within tissue and minimize trauma. Component(s) with cavity or opening features are attached to a brachytherapy seed or series of seeds. The cavity or opening features interact with the patient's tissue to fix the seed and component assembly in place and inhibit movement/migration of the seed(s). The cavity or opening features may optionally be filled with an adhesive or other beneficial material. The seed(s) or seed and component assembly may be inserted using a delivery device having a needle through which the seed(s) or assembly are implanted and a stylet extending through the needle to cut tissue and facilitate insertion of the needle. The stylet has a reduced diameter cutting tip to cut a narrow hole in tissue, and a tapered region that stretches the narrow hole to accommodate insertion of the larger diameter needle. | 12-31-2015 |
20160136454 | TETHERED AND/OR VISUALLY CODED BRACHYTHERAPY DEVICES AND RELATED METHODS - Brachytherapy devices include a respective flexible elongate tether with an external free tail end that has an opposing end that is attached to a proximal end portion of the corresponding strand. The tethers can be color-coded to match a color associated with the corresponding strand and/or radioactive material to facilitate visual correspondence for redeployment when a strand is in an undesired implanted location. Grids with color-coded rows may also be used to facilitate surgical placement and/or identification of respective strand/tether pairs. | 05-19-2016 |
20160184606 | Device for collimating electromagnetic radiation - The present invention relates to a device for collimating electromagnetic radiation comprising a shielding structure at least partially surrounding a radiation source which has an opening in a transmission direction (A), a plurality of lamellae of a material that absorbs electromagnetic radiation which are positioned in the opening, and collimator channels between the lamellae which extend in the transmission direction (A), wherein the lamellae have a height (H) in the range of ≧10 μm to ≦3000 μm. | 06-30-2016 |
20170232272 | CANCER TREATMENT APPARATUS | 08-17-2017 |