Class / Patent application number | Description | Number of patent applications / Date published |
540354000 | Additional chalcogen bonded directly to the hetero ring | 6 |
20090137796 | METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES - The present invention relates to a stereoselective synthesis of novel β-lactam dimers as useful precursors for the preparation of paclitaxel, docetaxel, and analogues thereof. More particularly, the new β-lactams are prepared from readily available and enantiomerically pure chiral auxiliaries. The β-lactams are then reacted with a suitably protected taxane to produce diastereomerically enriched side chain-bearing taxanes. Finally, the chiral auxiliary is cleaved and protecting groups are removed to provide the desired taxane. | 05-28-2009 |
20110065912 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES - A stereoselective synthesis of novel β-lactam dimers as useful precursors for the preparation of paclitaxel, docetaxel, and analogues thereof. More particularly, the new β-lactams are prepared from readily available and enantiomerically pure chiral auxiliaries. The β-lactams are then reacted with a suitably protected taxane to produce diastereomerically enriched side chain-bearing taxanes. Finally, the chiral auxiliary is cleaved and protecting groups are removed to provide the desired taxane. | 03-17-2011 |
540355000 | The additional chalcogen is bonded directly to the ring nitrogen | 2 |
20080281094 | Regioselective Functionalisation and Protection of Spirolactams - The invention provides highly functionalised spiro-fused lactams of en formula (I) having a cyclohexane moiety with the desired number of protected or un-protected functional groups or carbonated structures, which are introduced with high stereo and regioselectivity, as well as processes for their obtention. These compounds are useful for the synthesis of abroad range of bioactive molecules, such as condoritols and aminoinositols and their analogues. | 11-13-2008 |
20130296549 | PURIFICATION METHOD OF AZTREONAM - It discloses a process for refining Aztreonam, comprising the steps of 1) treating Aztreonam material with an alkali metal alkoxylate or an alkali earth metal alkoxylate under heating in the presence of a suitable solvent or a mixture of solvents, followed by adjusting the pH value with a suitable acid and cooling down to precipitate Aztreonam, which provides a primary purified Aztreonam; 2) adsorbing Aztreonam with strongly basic ion exchange resin, followed by eluting the resin and collecting the eluate, to provide a secondary purified Aztreonam after concentration under reduced pressure; 3) adjusting the pH value with a suitable acid to allow crystallization, followed by centrifuging and washing the resultant crystals, to provide a tertiary purified Aztreonam after drying. The refined Aztreonam product has a purity of no less than 99.2%, mostly no less than 99.5%, with little residue on ignition and significantly low content of heavy metals. | 11-07-2013 |
540360000 | Additional carbon bonded directly to the additional chalcogen | 2 |
20090088566 | Usage of Poly-3-Hydroxybutyrates in Preparation of Beta-Lactam Compounds - The present invention discloses the usage of Poly-3-hydroxybutyrates P(3HB) in preparation of β-lactam compounds and the method for the preparation of β-lactam compounds of formula (I) using Poly-3-hydroxybutyrates P(3HB) as followed: | 04-02-2009 |
20120142911 | SYNTHESIS OF TTX INTERMEDIATES - The present invention relates to the synthesis of intermediates which are useful in TTX synthesis and to the preparation thereof. | 06-07-2012 |