Class / Patent application number | Description | Number of patent applications / Date published |
514571000 | Ether oxygen single bonded to carboxylic acid, percarboxylic acid or salt thereof through an acyclic carbon or acyclic carbon chain | 38 |
20080262087 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS AND CELL LINES THAT EXPRESS SAID RECEPTORS AND USE THEREOF FOR IDENTIFICATION OF TASTE COMPOUNDS - The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners. | 10-23-2008 |
20080269335 | Crth2 Receptor Antagonists | 10-30-2008 |
20080269336 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS - The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia. | 10-30-2008 |
20080280986 | TREPROSTINIL TREATMENT FOR INTERSTITIAL LUNG DISEASE AND ASTHMA - The present invention describes methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof. | 11-13-2008 |
20080319078 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators - Triphenylethylene compounds of formula (I) are provided. The compounds are particularly useful for selective estrogen receptor modulation. | 12-25-2008 |
20090221708 | Medicinal preparation - Medicine, in particular broad spectrum medicinal preparations. This invention is based on the use of 4-chlorine-2-methyl-phenoxy-acetic acid of formula I, the pharmacologically acceptable derivatives thereof, for example on corresponding alkali metal salts of the acid and the derivatives in the form of pharmaceutical preparations exhibiting immunomodulating, anti-inflammatory and anti-tumoral properties and antiviral activity. The broad spectrum of therapeutic modalities of the inventive medicinal preparation and the fact that it does not produce side effects are proven by study. | 09-03-2009 |
20090221709 | METHODS OF MODIFYING TASTE SENSATION IN AN ANIMAL USING COMPOUNDS THAT MODULATE T1R1/T1R3 Or T1R2/T1R3 RECEPTORS - Methods of modifying taste sensation in an animal are provided. These methods comprise administrating compounds that modulate T1R1/T1R3 or T1R2/T1R3 receptors. | 09-03-2009 |
20100152295 | METHODS OF REDUCING SMALL, DENSE LDL PARTICLES - The present invention provides methods for increasing LDL particle size. | 06-17-2010 |
20110105616 | NOVEL LYSINE SALTS OF 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACID DERIVATIVES - The present invention is directed to a novel lysine salts, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by PPAR delta. The present invention is further directed to a novel process for the preparation of said lysine salts. | 05-05-2011 |
20110152374 | Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease - The invention relates to substituted phenoxyacetic acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation. | 06-23-2011 |
20110166235 | VISCOELASTIC SYSTEM FOR DRIFT REDUCTION - The invention relates to a viscoelastic system for drift reduction for pesticidal formulations, and the use thereof, wherein said formulation comprising at least one nitrogen-based cationic surfactant and at least one pesticide, wherein said pesticide contains at least one acid functional group associating with said cationic surfactant thereby forming a viscoelastic formulation. | 07-07-2011 |
20110237675 | PHARMACEUTICAL FORMULATIONS - The present invention provides a modified release formulation comprising an active agent in a hydrophilic polymer matrix wherein the active agent is a salt of fenofibric acid wherein the release rate of the formulation in an in vitro dissolution is substantially independent of the ionic strength of the dissolution media. | 09-29-2011 |
20110288176 | ETHACRYNIC ACID-CONTAINING COMPOSITION FOR PREVENTION OR TREATMENT OF TRANSGLUTAMINASE-RELATED DISEASES AND METHOD FOR PREVENTION OR TREATMENT OF TRANSGLUTAMINASE-RELATED DISEASES USING THE SAME - The present invention relates to ethacrynic acid and a transglutaminase inhibitor comprising a pharmaceutically acceptable salt of ethacrynic acid; more particularly, to ethacrynic acid for inhibiting the activity of transglutaminase involved in the pathogenesis of diseases in cases of altered expression, a transglutaminase inhibitor comprising a pharmaceutically acceptable salt of ethacrynic acid, and to a novel use of thereof. According to the present invention, there are provided ethacrynic acid, a transglutaminase inhibitor comprising active components of a pharmaceutically acceptable salt of ethacrynic acid and a transglutaminase inhibition method. The present ethacrynic acid, transglutaminase inhibitor comprising a pharmaceutically acceptable salt of ethacrynic acid or ethacrynic acid itself, and transglutaminase inhibition method provide a safer application without side effects to a patient having a disease where altered expression of transglutaminase is observed, thereby providing the inhibitory effect on transglutaminase. | 11-24-2011 |
20120122988 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS - The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia. | 05-17-2012 |
20120129941 | TREPROSTINIL TREATMENT FOR INTERSTITIAL LUNG DISEASE AND ASTHMA - The present invention describes methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof. | 05-24-2012 |
20120178814 | Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease - The invention relates to substituted phenoxyacetic acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation. | 07-12-2012 |
20120225946 | CHOLINE FENOFIBRATE DELAYED RELEASE COMPOSITIONS - Described are solid pharmaceutical compositions for oral administration comprising choline fenofibrate and an amount of an acid sufficient to substantially reduce a rate of dissolution of choline fenofibrate in an aqueous environment at pH 4.5 to less than about 50% in 2 hours. Processes for making the solid pharmaceutical composition for oral administration comprising: (a) mixing choline fenofibrate with an amount of an acid sufficient to substantially reduce a rate of dissolution of choline fenofibrate in an aqueous environment at pH 4.5 to less than about 50% in 2 hours; and (b) preparing a dosage form suitable for oral administration are also provided. | 09-06-2012 |
20120295981 | TETRASUBSTITUTED BENZENES - Tetrasubstituted benzenes that act as modulators of gamma secretase and their use in the treatment of one or more symptoms of treating neurodegenerative disorders, e.g., Alzheimer's disease, are described. | 11-22-2012 |
20120322875 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS - The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia. | 12-20-2012 |
20130018101 | SALTS OF FENOFIBRIC ACID AND PHARMACEUTICAL FORMULATIONS THEREOF - In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. | 01-17-2013 |
20130085181 | PHARMACEUTICAL FORMULATIONS - The present invention provides a modified release formulation comprising an active agent in a hydrophilic polymer matrix wherein the active agent is a salt of fenofibric acid wherein the release rate of the formulation in an in vitro dissolution is substantially independent of the ionic strength of the dissolution media. | 04-04-2013 |
20130158123 | METHOD OF TREATING NON-ALCOHOLIC FATTY LIVER DISEASE AND STEATOHEPATITIS - A compound of Formula (I): | 06-20-2013 |
20130331453 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS - The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia. | 12-12-2013 |
20140128473 | METHOD OF TREATING NON-ALCOHOLIC STEATOHEPATITIS - A compound of Formula (I): | 05-08-2014 |
20140155484 | METHOD OF TREATING LIVER DISORDERS - A compound of Formula (I): | 06-05-2014 |
20140155485 | Compositions and Methods for Treating Chronic Inflammation and Inflammatory Diseases - The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions. | 06-05-2014 |
20140350112 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF - The present invention relates to novel 1,3-diphenylpropane derivatives, pharmaceutical compositions comprising the same and therapeutic uses thereof, in particular in the fields of human and animal health. The compounds according to the present invention have intrinsic PPAR agonist properties. They are therefore of particular interest in the treatment of metabolic and/or inflammatory diseases and particularly peripheral and central diseases associated with the metabolic syndrome, such as diverse forms of steatohepatitis, type 2 diabetes, diverse neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. | 11-27-2014 |
20150018422 | AROMATIC RING COMPOUND - Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I): | 01-15-2015 |
20150031769 | METHODS FOR REDUCING TRIGLYCERIDE, TOTAL CHOLESTEROL AND LOW DENSITY LIPOPROTEIN BLOOD LEVELS - A compound of Formula (I): | 01-29-2015 |
20150080471 | METHODS FOR REDUCING TRIGLYCERIDE, TOTAL CHOLESTEROL AND LOW DENSITY LIPOPROTEIN BLOOD LEVELS - A compound of Formula (I): | 03-19-2015 |
20150290154 | Treatment of NAFLD and NASH - Treatment of NAFLD and NASH by therapy with MBX-8025 or an MBX-8025 salt. | 10-15-2015 |
20150320705 | METHOD OF INHIBITING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS WITH PHENOXYALKYLCARBOXYLIC ACIDS - A compound of Formula (I), or a metabolite thereof, or an ester of the compound of Formula (I) or the metabolite thereof, or a pharmaceutically acceptable salt of each thereof | 11-12-2015 |
20150321989 | METHOD OF TREATING IDIOPATHIC PULMONARY FIBROSIS - A compound of Formula (I): | 11-12-2015 |
20150322004 | METHOD OF TREATING ADVANCED NON-ALCOHOLIC STEATOHEPATITIS - A compound of Formula (I): | 11-12-2015 |
20150342913 | METHOD OF INHIBITING OR TREATING FIBROSIS - A compound of Formula (I) or a metabolite thereof, or an ester of the compound of Formula (I) or the metabolite thereof, or a pharmaceutically acceptable salt of each thereof, wherein Formula (I), m, n, X | 12-03-2015 |
20160081955 | SOBETIROME IN THE TREATMENT OF MYELINATION DISEASES - Methods of treating a subject having or at risk of developing a neurodegenerative disease or condition associated with demyelination, insufficient myelination, or underdevelopment of myelin sheath are described. The methods include administration of a therapeutically effective amount of sobetirome, or a pharmaceutically acceptable salt thereof. | 03-24-2016 |
20180021275 | METHOD OF TREATING IDIOPATHIC PULMONARY FIBROSIS | 01-25-2018 |
20190142776 | Treatment of NAFLD and NASH | 05-16-2019 |