Class / Patent application number | Description | Number of patent applications / Date published |
436171000 | Spectrum analysis (e.g., flame photometry, etc.) | 27 |
20080241954 | METHODS FOR DETERMINING THE STATUS OF COPD IN HUMANS - A method of determining the status of chronic obstructive pulmonary disease (COPD) of a human that includes the steps of performing a spectral analysis of a sputum sample collected from the human; comparing the spectra produced by the analysis against a reference; and determining the status of COPD in the human based upon any determined variations. | 10-02-2008 |
20080299673 | Method for Employing a Biosensor to Detect Small Molecules ("Fragments") that Bind Directly to Immobilized Protein Targets - The invention provides method of detecting interactions of small molecules with target molecules. | 12-04-2008 |
20090311798 | SE(R)RS DISPLACEMENT ASSAY - A detection method is described for detecting an analyte, in particular nucleic acids, in a sample using SE(R)RS, without the need for labeling of the analyte. The detection method is based on the displacement of a labeled surrogate target probe from a capture probe by the analyte in the sample. The present invention also provides a corresponding detection system, to a disposable cartridge for use in such a system, and to a combination of surrogate target probe and capture probe. | 12-17-2009 |
20100022020 | Compositions for surface enhanced infrared absorption spectra and methods of using same - A composition comprising a substrate and at least one adsorbate associated with the substrate wherein the composition has an enhanced infrared absorption spectra. A method comprising tuning a nanoparticle to display a plasmon resonance in the infrared, associating an adsorbate with the nanoparticle to form an adsorbate associated nanoparticle, and aggregating the adsorbate associated nanoparticle. A method of preparing a SERS-SEIRA composition comprising fabricating a nanoparticle substrate, functionalizing the nanoparticle substrate to form a functionalized substrate, dispersing the functionalized substrate in solution to form a dispersed functionalized substrate, and associating the dispersed functionalized substrate with a medium. | 01-28-2010 |
20100035359 | FUNCTIONALISED POLYMERS FOR BINDING METAL SURFACES - The invention relates generally to polyvalent macromolecules comprising: (a) a polymer backbone and (b) pendent groups attached to said polymer backbone, wherein some or all of said pendent groups comprise: (i) optionally a linker, (ii) a surface-seeking group, which is capable of binding strongly to a metal surface, (iii) optionally a chromophore, which is detectable by at least one spectroscopic method. Such molecules can modify metal surfaces and have a variety of uses including (without limitation) appending chromophores to metal surfaces without the need to establish complex chemistry; for the stabilisation and labelling of metal nanoparticles; and for preparing and aggregating nanoparticles in a controlled fashion. | 02-11-2010 |
20100093105 | MICROFLUIDIC DEVICE USING CENTRIFUGAL FORCE, METHOD OF MANUFACTURING THE MICROFLUIDIC DEVICE AND SAMPLE ANALYZING METHOD USING THE MICROFLUIDIC DEVICE - Provided is a microfluidic device including: a sample chamber; at least one analyzing unit receiving a sample from the sample chamber and detecting components contained in the sample according to a reaction of the sample and a reagent; and a denaturation detection chamber determining the storage condition of the microfluidic device, wherein the denaturation detection chamber accommodates a material whose light absorption changes according to the temperature and the water thereof | 04-15-2010 |
20100129926 | COPD DETERMINATION - There is provided a method of determining the status of chronic obstructive pulmonary disease (COPD) of a human. The method comprises (a) performing a spectral analysis of a sample collected from said human; (b) comparing the spectra produced by said analysis at (a) against a reference; and (c) determining the status of COPD in said human based upon any variations determined at (b). Also provided is an apparatus for determining COPD. | 05-27-2010 |
20100167412 | SENSOR SYSTEM FOR DETERMINING CONCENTRATION OF CHEMICAL AND BIOLOGICAL ANALYTES - A sensor system for determining a concentration of chemical and biological analytes is disclosed, which comprises a disposable reagent-carrying pipette tip; a liquid handling unit to which the pipette tip can be detachably mounted, the liquid handling unit capable of withdrawing liquid into the pipette tip; at least one light source; at least one photodetector, the detector capable of generating an electronic signal response indicative of light passed through or generated from the interior space of the pipette tip; and an electronic circuit means for processing, storing and transmitting the electronic signal response and controlling the light source. | 07-01-2010 |
20100221843 | Device for Investigating Chemical Interactions and Process Utilizing Such Device - The invention relates to a device for investigating reactions between interactive species, said device comprising: one or more plasma deposited layers, which layers comprise one or more first pre-selected functional group species, which functional group species are interactible with a pre-selectable second species. | 09-02-2010 |
20100291701 | CYANIDE AND RELATED SPECIES DETECTION WITH METAL SURFACES - An assay method and kit for detecting a chemical. The method and kit utilize a metal surface capable of surface enhanced Raman Scattering. The metal surface may be provided in the form of one or more nanoparticles, to increase the surface enhanced Raman Scattering capability of the metal surface. The nanoparticles may be treated with one or more additives to further enhance or maintain the surface enhanced Raman Scattering capability of the nanoparticles. | 11-18-2010 |
20100330692 | AMMONIA DETECTION AND MEASUREMENT DEVICE - There is disclosed an apparatus and method for detecting and measuring volatile acidic or basic components including ammonia, ammonium, or volatile amines (compound) in a gas or liquid state fluid. Specifically, the present invention provides a PTFE-carrier solid phase indicator film having an ammonia-sensitive indicator dye embedded therein, such that the dye moiety changes color or spectral properties upon exposure to the compound to be detected. | 12-30-2010 |
20110097815 | ANIONIC SURFACTANT DETECTION - Disclosed herein are methods for the detection and/or quantification of anionic surfactants. Also disclosed herein are test kits, which utilize the disclosed methods, to estimate the anionic surfactant concentration in samples, such as environmentally-derived samples. In some specific embodiments, the method and the test kit may be used to detect, among other things, aqueous film forming foams that comprise anionic surfactants. | 04-28-2011 |
20110300638 | Ion Mobility Spectrometers - An ion mobility spectrometer has a reaction region separated from a drift region by an electrostatic gate. A doping circuit supplies a dopant to the reaction region but the drift region is undoped. Two high field ion modifiers are located one after the other in the drift region. One ion modifier can be turned on to remove dopant adducts from the admitted ions, or both ion modifiers can be turned on so that the ions are also fragmented. In this way, several different responses can be produced to provide additional information about the nature of the analyte substance and distinguish it from interferents. | 12-08-2011 |
20120100629 | Device For Investigating Chemical Interactions And Process Utilizing Such Device - The invention relates to a device for investigating reactions between interactive species, said device comprising: one or more plasma deposited layers, which layers comprise one or more first pre-selected functional group species, which functional group species are interactible with a pre-selectable second species. | 04-26-2012 |
20120135536 | Method and Apparatus for Detecting and Quantifying a Chemical Substance Employing an Optical Transmission Property of Metallic Islands on a Transparent Substrate - A sensor for use in detecting and analyzing predetermined chemical substances is presented. The sensor comprises: a first structure configured for binding to a certain substance and comprising a substantially transparent substrate with respect to electromagnetic radiation of a predetermined wavelength range and a plurality of metallic islands deposited onto the transparent substrate and having a first spectral transmission profile with respect to the electromagnetic radiation of the predetermined wavelength range; the metallic islands comprising metallic films having a thickness selected such that binding of said certain substance to the first structure provides a change in a localized surface plasmon extinction in the metallic films being in a predetermined correlation with a change in a spectral transmission profile of the electromagnetic radiation of the predetermined wavelength range transmitted through the first structure and the substance as compared to said first spectral transmission profile, thereby enabling detection of said substance. | 05-31-2012 |
20120264225 | METHOD OF QUANTITATIVE ANALYSIS OF HEXAVALENT CHROMIUM IN CHROMATE COATING AND METHOD FOR CONTROLLING HAZARDOUS ELEMENT IN ENCAPSULATING RESIN OF RESIN ENCAPSULATION SEMICONDUCTOR DEVICE - A method for controlling a hazardous element in an encapsulating resin of a resin encapsulation semiconductor device includes subjecting the device to qualitative analysis with a fluorescent X-ray analyzer to judge whether the hazardous element is contained in the encapsulating resin, aligning a plurality of devices with each of upper and lower surfaces of the devices brought into a plane, setting the surfaces of the devices to cover a full X-ray irradiation plane and subjecting the devices to quantitative analysis with the fluorescent X-ray analyzer to obtain an analytical value of the hazardous element in the encapsulating resin for upper and lower surfaces of the devices, and judging whether the analytical value of the hazardous element which is less influenced by a coexistent element of the analytical values for the upper and lower surfaces of the devices exceeds a threshold value. | 10-18-2012 |
20130017619 | ANIONIC SURFACTANT DETECTION - Disclosed herein are methods for the detection and/or quantification of anionic surfactants. Also disclosed herein are test kits, which utilize the disclosed methods, to estimate the anionic surfactant concentration in samples, such as environmentally-derived samples. In some specific embodiments, the method and the test kit may be used to detect, among other things, aqueous film forming foams that comprise anionic surfactants. | 01-17-2013 |
20130109105 | INFRARED EMISSION SPECTROSCOPY OF SAMPLES WITH TIME DEPENDENT INFRARED EMISSION | 05-02-2013 |
20130130400 | INCREASING THE USABLE DYNAMIC RANGE IN PHOTOMETRY - An optical device for determining the presence and/or concentration of analytes in a sample is presented. The optical device comprises a detector and a detection unit comprising optical path components. The detection unit has wavelength-dependent responsivity. The optical device further comprises a light source for emitting light of different respective usable wavelength ranges. The light is guidable through the optical path to the detector to generate baseline signals and response signals relative to the baseline signal indicative of the presence and/or concentration of analytes in the optical path. The intensity of the light reaching the detector is adjusted inverse to the wavelength-dependent responsivity with respect to at least two respective usable wavelength ranges so that a reduction of the ratio between the maximum baseline signal at one of the selected usable wavelength ranges and the minimum baseline signal at another of the selected usable wavelength ranges is obtained. | 05-23-2013 |
20130267035 | Isotopic Chemical Analysis using Optical Spectra from Laser Ablation - This disclosure provides systems, methods, and apparatus related to performing isotopic analysis of a sample. In one aspect a method includes applying laser energy to a region of a sample with a laser to generate a plasma and recording a spectrum generated by a plurality of molecular species in the plasma with a device. | 10-10-2013 |
20140057362 | LATERAL FLOW ASSAY ANALYSIS - Lateral flow assay analysis is shown and described. In one embodiment, the lateral flow assay comprises a surface having a reflectance profile that is adapted to enable monitoring of the assay continuously until the detection of an analyte. In other embodiments, a lateral flow assay system includes an incubator and a reader, wherein the incubator incubates the assay concurrently as the reader generates a test result. Further, an assay measurement apparatus may include an optical detector to perform continuous image detection of the assay to generate a diagnostic test result. | 02-27-2014 |
20140113382 | PLASMONIC JUNCTIONS FOR SURFACE-ENHANCED SPECTROSCOPY - The invention relates to the use of a construct for the detection of an analyte using surface enhanced spectroscopic techniques. The construct includes linked surfaces, where the link is formed by a linker providing a fixed inter-surface separation between the linked surfaces, wherein the linker is a linking compound, and at least one of the surfaces is the surface of a nanoparticle. The linking compound is suitable for interacting with the analyte. The linking compound may be a cucurbituril. The surface enhanced spectroscopic technique may be surface enhanced Raman spectroscopy (SERS). | 04-24-2014 |
20140234983 | METHOD FOR PRODUCING METALLIC NANOPARTICLES FUNCTIONALIZED WITH FLUORESCENT ORGANIC MOLECULES - The present invention relates to a method of obtaining metal nanoparticles functionalized with fluorescent organic molecules by means of the treatment of one or more metal salts with a reducing agent in the presence of a fluorescent organic molecule. The invention also relates to the metal nanoparticles obtainable by said method and to their use for detecting molecules and analytes. | 08-21-2014 |
20150099309 | MULTI-CHANNEL LIGHT MEASUREMENT METHODS, SYSTEMS, AND APPARATUS HAVING REDUCED SIGNAL-TO-NOISE RATIO - Disclosed is a multi-channel light measurement system adapted to illuminate and measure a test sample in a vessel. The multi-channel light measurement system has at least one photodetector per channel and a variable integrate and hold circuit coupled to each photodetector, the variable integrate and hold circuit allows adjustment of a sampling factor selected from a group of an integration time, a value of capacitance, an area of a discrete photodetector array, or any combination thereof. The system may readily equilibrate reference intensity output for multiple channels. Methods and apparatus are disclosed, as are other aspects. | 04-09-2015 |
20150301017 | METHODS OF DIAGNOSING PROLIFERATIVE DISORDERS - The present invention relates to methods of diagnosing and/or prognosing proliferative disorders, especially brain cancers (e.g. gliomas). In particular, the present invention provides a means to conveniently detect malignant tumours merely by assaying or analysing blood (particularly blood serum). Cytokines and/or angiogenesis factors in blood serum have been found to be surprisingly powerful at indicating the presence of brain cancers in a subject. Moreover, spectroscopic analysis, especially ATR-FTIR analysis, of a blood sample has been demonstrated to be surprisingly effective at producing a signature that can be correlated with the presence, extent, severity, or aggressiveness of malignant tumours in a subject. | 10-22-2015 |
20160033410 | OPTICAL EMISSION COLLECTION AND DETECTION DEVICE AND METHOD - This invention generally relates to optical devices that can collect and detect signal emissions effectively while allowing the excitation light path and the sample flow path to coexist non-obstructively in a compact format. The device has various embodiments, such as an embodiment including a plurality of reporters disposed on a sensing surface, wherein each one of the plurality of reporters is configured to react with a least one target analyte, a hyperspectral detection module configured to capture hyperspectral image data corresponding to the plurality of reporters, and a controller. The controller is configured to receive the hyperspectral image data from the hyperspectral detection module and generate a temporal spectral signature corresponding to each one of the plurality of reporters from the received hyperspectral image data. | 02-04-2016 |
20160061742 | MEASURING DEVICE AND MEASURING METHOD - A measuring device ( | 03-03-2016 |