Class / Patent application number | Description | Number of patent applications / Date published |
435287300 | With sample or reagent mechanical transport means | 43 |
20080206855 | Automated Compound Screening Using Gel-Permeation Matrix and Pin-Based Sample Transfer - A system for identifying biological activity of one or more samples using prolonged signaling. The system includes a sample plate, an assay in a permeable media, a test plate, an automated liquid handler and an electronic reader. The sample plate includes one or more individual wells which are used for storing one or more samples. A feature of the system uses an automated liquid handler to aspirate samples from the sample plate and to dispense each of these samples directly onto the assay in the permeable media. The automated liquid handler transfers the test plate in communicable range to an electronic reader for reporting transient biological events. | 08-28-2008 |
20080305538 | Rapid and Sensitive Detection of Bacteria in Blood Products, Urine, and Other Fluids - The invention provides methods of detecting bacteria in fluids, including blood, platelets and other blood products for transfusion, and urine. The methods are based on lysing the bacteria to release ATP and detecting the ATP. Eukaryotic cell contamination is a problem to be overcome, because eukaryotic cell contain large amounts of ATP. Thus, some of the methods involve separating intact eukaryotic cells (e.g., platelets) from intact bacterial cells before lysing the bacterial cells to release ATP, contacting the ATP with an ATP-consuming enzyme that catalyzes a reaction, and monitoring the enzyme-catalyzed reaction. Typically, the enzyme is luciferin, and the reaction is monitored by detecting light produced by the luciferin. Other methods of the invention involve contacting a fluid sample with a support surface that binds bacterial cells, lysing the bacterial cells to release ATP, contacting the ATP with an ATP-consuming enzyme, and monitoring the enzyme-catalyzed reaction. Apparatuses for carrying out the methods are also disclosed. | 12-11-2008 |
20080318306 | Device for Supplying Blood Tubes to a Whole Blood Analyser - A device including a pre-analytical module provided with at least one tube stirrer for homogenizing blood and preventing clot formation and disposed on a line for single-tube transfer between an area for storing analyzable tubes, and at least one unitary operating whole blood analyzer and automatic tube-loading/unloading device arranged between the tube stirrer and the single-tube transfer line. The device is suitable for blood analyzers. | 12-25-2008 |
20090203117 | Apparatus for Processing Biological Material - The present invention relates to an apparatus for processing biological materials, comprising a platform having a plurality of sample receiving areas located thereon, each sample receiving area being substantially enclosed in a holding means, the apparatus also having at least one liquid carrier member mounted for supplying liquid to and/or removing liquid from the sample receiving area, and the platform and liquid carrier member being movable relative to one another so as to move sequential sample receiving areas into orientation with the liquid carrier member. The present invention is particularly suited to processing biological material (and in particular cell suspensions) for cytogenetic analysis. | 08-13-2009 |
20090325279 | PROCESS AND DEVICE FOR PRODUCING REAGENT CARRIERS - The invention concerns a process for producing reagent carriers having a binding capability that are suitable for determining analytes in liquids, wherein the process comprises at least one step of treating a respective reagent carrier body in particular by transferring material between a treatment device and the reagent carrier body in a preparation device and wherein this treatment step takes place on the moving reagent carrier body during its transport in the preparation device or during a movement of the treatment device relative to the reagent carrier body in the preparation device. | 12-31-2009 |
20100047902 | Transfer device for culture vessel, culture device and holder for culture vessel - A transfer device for a culture vessel for transferring a culture vessel for culturing a cell, a culture device including the transfer device for a culture vessel, and a holder for a culture vessel for holding a culture vessel, in which the transfer device for a culture vessel includes a transferring unit transferring a culture vessel for culturing a cell, an inputting unit inputting a kind of the culture vessel, a speed setting unit setting a transfer speed of the culture vessel based on a kind of the culture vessel inputted to the inputting unit, and a controlling unit controlling a transfer speed of the transferring unit to be the transfer speed set by the speed setting unit. | 02-25-2010 |
20100055772 | Reagent preparing apparatus, sample processing apparatus and reagent preparing method - The present invention is to present a reagent preparing apparatus for preparing a reagent for processing a sample, by using a first liquid and a second liquid, comprising: a storage unit for storing liquid; and a constant amount liquid quantifying unit comprising a constant amount holding instrument which is used in common to hold a constant amount of the first liquid and to hold a constant amount of the second liquid, the constant amount liquid quantifying unit performing an operation of transferring the constant amount of the first liquid to the storage unit and performing an operation of transferring the constant amount of the second liquid to the storing unit. | 03-04-2010 |
20100112679 | Method And Apparatus For Syringe-Based Sample Introduction Within A Flow Cytometer - An apparatus for introducing a specimen into a flow cytometer comprises: a syringe having a hollow barrel containing the specimen, a plunger partially within the barrel and a needle that extends into a volume of a nozzle of the flow cytometer; a one-way port in the nozzle forming a seal against the needle; a mounting platform coupled to both the syringe and to the flow cytometer; and a syringe pump coupled to the plunger, the syringe pump comprising a motor, a drive mechanism coupled to the motor; and a clamping mechanism coupled to the drive mechanism, wherein the motor operates the drive mechanism so as to cause the clamping mechanism to depress the plunger into the barrel. | 05-06-2010 |
20100233794 | SUCTION DEVICE AND ANALYSIS DEVICE - Each of nozzles includes a micropore which is used as a channel, and the channel is exposed to the outside in the vicinity of a front end of the nozzle. An arm supports the nozzles so that the front ends of the nozzles are movable in an insertion/extraction direction, in which the front ends are inserted into or extracted from a specimen container, and the front ends of the nozzles are able to be simultaneously located in the specimen container. An arm movement mechanism and a nozzle movement mechanism respectively move the nozzles so as to move any one of the front ends of the nozzles in the insertion/extraction direction. Particularly, the nozzle movement mechanism is able to change a relative positional relationship of the front end of the nozzle movement mechanism with respect to the insertion/extraction direction. | 09-16-2010 |
20100261264 | TEST APPARATUS - A test apparatus is disclosed for measuring a component. The test apparatus maintains the amount of a specimen to be used for a reaction with a reagent at a constant value by allowing all of a fluid specimen to be measured and thus improves the accuracy and reproducibility of a test. The test apparatus includes a solution storage unit capable of holding a solution beforehand or allowing a solution to be filled therein, a capillary having a first end part and a second end part for storing the fluid specimen, and a test piece for measuring the component to be measured in the specimen. The solution storage unit and the second end part of the capillary are communicable with each other, and the first end part of the capillary is placed so as to be in contact with the test piece. | 10-14-2010 |
20100273248 | SOLUTION BAG FOR APPARATUS FOR CHEMICALLY ANALYZING BLOOD - The present invention provides a solution bag that is used for medical treatment and stores solution used for an apparatus for analyzing blood chemistry that measures and analyzes the concentrations of electrolytes, the partial pressures of gases, and the concentrations of metabolites or the volume ratio of red blood cells contained in blood. The solution bag for an apparatus for analyzing blood chemistry of the present invention includes: a receptacle that contains a solution; a valve body that is attached to the receptacle and has a through-hole longitudinally formed therein; a valve spool that is disposed in the thorough-hole of the valve body; and a solution leakage preventing unit that is disposed in the valve spool, in which the valve body has a flow channel and a solution discharging pipe spaced at a predetermined distance from each other, and the solution leakage preventing unit of the valve spool includes a first blocking member that prevents the solution from leaking outside and a second blocking member that is spaced apart from the first blocking member and stops or allows the solution flow from the flow channel to the solution discharging pipe. | 10-28-2010 |
20100285572 | Inhibition Assay Method and Device for Detection of Antibiotics - An aspect of the disclosure is a method and device for the detection of antibiotics in a sample. Embodiments include a microbial culture with growth indicators and sensitivity adjustment reagents. Adjustment reagents include a variety of antibiotic binders that can be added to microbial culture to reduce sensitivity to certain antibiotics. Some embodiments include multiple buffers with a variety of pKa ranges. Some embodiments also include a complete self-contained apparatus for sampling and testing. | 11-11-2010 |
20100291669 | System for rapid identification and/or characterization of a microbial agent in a sample - An automated instrument for identification and/or characterization of a microbial agent present in a sample. The instrument includes (a) a sample removal apparatus operative to remove a test sample from a specimen container and add the test sample to a disposable separation device; (b) a separation and concentration apparatus operative on the separation device to separate the microbial agent from other components which may be present in the test sample and concentrate the microbial agent within the separation device; and (c) a identification and/or characterization module interrogating the concentrated microbial agent to identify and/or characterize the microbial agent. | 11-18-2010 |
20100297747 | SYSTEM AND METHOD FOR MONITORING CELL GROWTH - Microsystem for monitoring cell growth. A microfluidic structure is designed to allow cells to circulate therethrough and the microfluidic structure includes modules to monitor mass, mass density and fluorescence of the cell. | 11-25-2010 |
20110003372 | MICROFLUIDIC GRADIENT DEVICES - Provided herein are apparatuses, systems and methods for the efficient generation of gradients. | 01-06-2011 |
20110014687 | CONNECTION DEVICE AND ANALYZER - A connection device for connecting to a plurality of fluid containers that have openings, and a sample analyzer body for analyzing samples using reagent, is disclosed, which comprises: a plurality of tubular members for passing liquid, the plurality of tubular members being inserted in the fluid containers through the openings of the plurality of fluid containers; a holding member to hold the plurality of tubular members; and a plurality of cover members to be fitted to the opening of the fluid container, wherein the plurality of cover members are arranged in a predetermined positional relationship on the holding member side of the plurality of tubular members; configured with a continuously decreasing cross sectional area toward the fluid container side; and the shape of the cross section of the cover member is substantially the same as the shape of the corresponding opening of the fluid container. | 01-20-2011 |
20110076755 | SAMPLE PREPARATION APPARATUS AND CELL ANALYZER - A sample preparation apparatus comprising: a storage chamber that can store therein a liquid sample including an analysis target to be analyzed; a concentrated sample storage chamber that is provided to communicate with the storage chamber and that stores therein concentrated liquid having an analysis target having a higher concentration than that of the liquid sample; and an analysis target transportation section for transporting the analysis target included in the liquid sample stored in the storage chamber to the concentrated sample storage chamber. A cell analyzer is also disclosed. | 03-31-2011 |
20110124096 | AUTOMATED CONTAINER MANAGEMENT DEVICE FOR MICROBIAL DETECTION APPARATUS - The present invention is directed to a method and container locator means for moving a container among one or more work-flow stations within an apparatus. The apparatus of the present invention may include a means for automated loading, a means for automated transfer and/or a means for automated unloading of a container (e.g., a specimen container). In one embodiment, the apparatus can be an automated detection apparatus for rapid non-invasive detection of a microbial agent in a test sample. The detection system also including a heated enclosure, a holding means or rack, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system. | 05-26-2011 |
20110244559 | Fabrication Method of Microfluidic Circuit, and Microfluidic Circuit Fabricated by Method Thereof - A fabrication method of a microfluidic circuit is provided, dispensable of mask registration, absent of deviation in mask positioning, and inexpensive in fabrication cost. The fabrication method of a microfluidic circuit has a light transmissive substrate stacked on a light absorptive substrate, and the light transmissive substrate welded with the light absorptive substrate for bonding by directing light through the light transmissive substrate. The microfluidic circuit includes a microchannel at the bottom face of the light transmissive substrate and/or at the top face of the light absorptive substrate. The method includes the step of forming, at the light transmissive substrate, a light attenuation region attenuating transmittance of light towards the microchannel when light is directed through the light transmissive substrate. | 10-06-2011 |
20120252110 | CELL CULTURE APPARATUS - A cell culture apparatus includes: an isolator in which a sterile space accommodating a cell incubator filled with a culture solution containing cells to be cultured is disposed; a sampling unit configured to sample the culture solution in the cell incubator; a delivery flow path through which an inside of the sterile space and an outside of the sterile space communicate with each other, the delivery flow path configured to limit a flow in the delivery flow path to a direction that is directed from the inside of the sterile space toward the outside of the sterile space; and a culture solution delivering section configured to deliver the sampled culture solution to the outside of the sterile space via the delivery flow path. | 10-04-2012 |
20120329144 | SAMPLE ANALYSIS CARTRIDGE AND SAMPLE ANALYSIS CARTRIDGE READER - A sample analysis cartridge and a sample cartridge reader are provided. In measuring a particular component included in a sample flowing in a microfluidic channel, a numerical value of hematocrit is reflected to thus improve the accuracy of measurement of the particular component. | 12-27-2012 |
20130183751 | CARRIER DEVICE AND CULTURE APPARATUS - A carrier device may include a loading board, a moving mechanism to move the loading board horizontally for a storage member storing a plurality of containers for storing liquid to be loaded on the loading board; a base material having set thereon the loading board and moving mechanism, and a first mounting member mounted to the base material. | 07-18-2013 |
20140057341 | LIVE BIOLOAD DETECTION USING MICROPARTICLES - The present invention provides methods to concentrate cells onto microparticles, to concentrate the microparticles, and to detect the cells. The present invention also includes unitary sample preparation and detection devices to be used in accordance with the methods. | 02-27-2014 |
20140073043 | SYSTEMS AND METHODS FOR MULTI-ANALYSIS - Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. | 03-13-2014 |
20140080205 | SYSTEM OR DEVICE FOR BIOCHEMICAL ANALYSIS HAVING AT LEAST ONE ELECTROOSMOTIC PUMP - An electroosmotic (EO) pump is provided that includes a housing having a pump cavity, a porous core medium and electrodes. The porous core medium is positioned within the pump cavity to form an exterior reservoir that extends at least partially about an exterior surface of the porous core medium. The porous core medium has an open inner chamber provided therein. The inner chamber represents an interior reservoir. The electrodes are positioned in the inner chamber and are positioned proximate the exterior surface. The electrodes induce flow of a fluid through the porous core medium between the interior and exterior reservoirs, wherein a gas is generated when the electrodes induce flow of the fluid. The housing has a fluid inlet to convey the fluid to one of the interior reservoir and the exterior reservoir. The housing has a fluid outlet to discharge the fluid from another of the interior reservoir and the exterior reservoir. The housing has a gas removal device to remove the gas from the pump cavity. | 03-20-2014 |
20140256030 | Scalable Biochip and Method for Making - The present disclosure provides a biochip and methods of fabricating. The biochip includes a fluidic part and a sensing part bonded together using a polymer. The fluidic part has microfluidic channel pattern on one side and fluidic inlet and fluidic outlet on the other side that are fluidly connected to the microfluidic channel pattern. The fluidic inlet and fluidic outlet are formed by laser drilling after protecting the microfluidic channel pattern with a sacrificial protective layer. The polymer bonding is performed at low temperature without damaging patterned surface chemistry on a sensing surface of the sensing part. | 09-11-2014 |
20140256031 | SEMICONDUCTOR MICRO-ANALYSIS CHIP AND SAMPLE LIQUID FLOWING METHOD - According to one embodiment, a semiconductor micro-analysis chip for detecting fine particles in sample liquid includes a semiconductor substrate, a flow channel formed in the semiconductor substrate and having a sample liquid inlet and sample liquid outlet at end portions thereof, and an absorber provided on at least part of the sample outlet of the flow channel to absorb the sample liquid. | 09-11-2014 |
20140273190 | MICRO-CHANNEL CHIP - A micro-channel chip comprises two gas control channels, a liquid inlet channel, a liquid outlet channel, a piston channel, and a micro pump including two micro-valves and a plurality of micro-channels. One of the gas control channels communicates with one end of the piston channel and communicates with the two micro valves and the liquid inlet channel respectively via the micro-channels. The other one of the gas control channels communicates with the two micro-valves and the liquid outlet channel respectively via the micro-channels. The other end of the piston channel communicates with one of the micro-valves via the micro-channels. | 09-18-2014 |
20140287487 | DEVICE, SYSTEMS AND METHODS FOR ANALYZING A TARGET ANALYTE - This disclosure is directed to a cap for obtaining a target analyte from a suspension. The cap introduces a magnetic field or a magnetic gradient to the tube to draw the target analyte bound to a particle to the cap. In one aspect, a cap includes a magnetic insert and a receiving piece. The magnetic insert includes a stopper and a magnet extending from the stopper; and, the receiving piece, which is configured to hold the magnetic insert, includes a receiving stopper and a sheath. The sheath may include imaging slides on opposite sides of the sheath. In another aspect, the cap may include a stopper and an embedded magnet. The cap may include an analysis piece on a bottom end of the stopper. In yet another aspect, the cap may include a fluid compartment and a filter at a bottom end of the stopper. | 09-25-2014 |
20140322801 | OPTICAL IMAGING BASED ON VISCOELASTIC FOCUSING - An apparatus arranged for examining particles, comprising: a cartridge having at least one microchannel, a viscoelastic fluid flowing in the microchannel, the fluid comprising a suspension of particles, thereby effecting alignment of the particles in at least one-dimensional array parallel to the fluid flow, and an optical magnifying means generating an image of the particles in the microchannel. | 10-30-2014 |
20150010993 | SYSTEM FOR CONDUCTING THE IDENTIFICATION OF BACTERIA IN URINE - A system for conducting the identification and quantification of micro-organisms, e.g., bacteria in urine samples which includes: 1) several disposable cartridges for holding four disposable components including a centrifuge tube, a pipette tip having a 1 ml volume, a second pipette tip having a 0.5 ml volume, and an optical cup or cuvette; 2) a sample processor for receiving the disposable cartridges and processing the urine samples including transferring the processed urine sample to the optical cups; and 3) an optical analyzer for receiving the disposable cartridges and configured to analyze the type and quantity of micro-organisms in the urine sample. The disposable cartridges with their components including the optical cups or cuvettes are used in the sample processor, and the optical cups or cuvettes containing the processed urine samples are used in the optical analyzer for identifying and quantifying the type of micro-organism existing in the processed urine samples. | 01-08-2015 |
20150017713 | Micro Fluid Dosing Unit and Testing Device for Biomaterial - A micro fluid dosing unit includes a test container containing biomaterial needing oxygen. The test container has at least one first container which contains water and at least one second container which contains a pharmacological substance, wherein the first and the second containers have a container outlet leading to the test container and are mounted on a common valve carrier plate containing control channels, which includes control channel ports for control valves to be coupled thereto. In the valve carrier plate a separate valve control chamber is formed for each container, which is sealed by a membrane, wherein associated container outlets are opened and closed by the membrane movement. | 01-15-2015 |
20150056689 | SYSTEM LAYOUT FOR AN AUTOMATED SYSTEM FOR SAMPLE PREPARATION AND ANALYSIS - A sample preparation and analysis system. The system includes a housing with a sample preparation station and a sample analysis station positioned within the housing. The sample analysis station is spaced away from the sample preparation station. A transport assembly is configured to move at least one sample within the housing and between the sample preparation station and the sample analysis station. | 02-26-2015 |
20150299639 | SYSTEM AND METHOD FOR INCUBATION AND READING OF BIOLOGICAL CULTURES - The present invention describes an integrated incubator and image capture module that regulates the incubator atmosphere and obtains high-resolution digital images of sample specimens. The incubator has a cabinet type enclosure that enables the provision of a controlled environment to the contents of the incubator by having at least three ports on one face of the cabinet for the passage of sample containers. Additionally, an image capture module is located immediately adjacent to the incubator. In this regard, using at least three separate access/egress points for the sample containers streamlines operation of the system and enhances preservation of the incubator environment. Furthermore, locating the image capture module directly adjacent to the incubator reduces the amount of time a sample container is exposed to the external environment, thereby reducing the extent to which samples are exposed to potential contaminants and reducing the exchange of the lab and ambient atmospheres. | 10-22-2015 |
20150330880 | DEVICE, SYSTEMS AND METHODS FOR ANALYZING A TARGET ANALYTE - This disclosure is directed to a cap for obtaining a target analyte from a suspension. The cap introduces a magnetic field or a magnetic gradient to the tube to draw the target analyte bound to a particle to the cap. In one aspect, a cap includes a magnetic insert and a receiving piece. The magnetic insert includes a stopper and a magnet extending from the stopper; and, the receiving piece, which is configured to hold the magnetic insert, includes a receiving stopper and a sheath. The sheath may include imaging slides on opposite sides of the sheath. In another aspect, the cap may include a stopper and an embedded magnet. The cap may include an analysis piece on a bottom end of the stopper. In yet another aspect, the cap may include a fluid compartment and a filter at a bottom end of the stopper. | 11-19-2015 |
20150355078 | SYSTEMS AND METHODS FOR DETERMINING A COMPLETE BLOOD COUNT AND A WHITE BLOOD CELL DIFFERENTIAL COUNT - Systems and methods analyzing body fluids such as blood and bone marrow are disclosed. The systems and methods may utilize an improved technique for applying a monolayer of cells to a slide to generate a substantially uniform distribution of cells on the slide. Additionally aspects of the invention also relate to systems and methods for utilizing multi color microscopy for improving the quality of images captured by a light receiving device. | 12-10-2015 |
20160061851 | TEST SYSTEM - Provided is a test system operable with a simplified structure. A test system includes a test device and a test device each of which transports and tests a sample. The test device includes a master control unit, which performs assignment of samples to the test device and the test device, and control of a transport operation of the sample assigned to the test device. The test device includes a slave control unit, which controls a transport operation of the sample assigned to the test device by the master control unit. | 03-03-2016 |
20160068796 | DEVICE AND METHOD FOR MICROBIOLOGICAL ANALYSIS OF BIOLOGICAL SAMPLES - A device for microbiological analyses on samples of body fluids including: an incubation area for containers containing the samples; an analyzer for analyzing the inner atmosphere of the containers; a sorting system to sort the containers according to the carbon dioxide content detected by the analyzer. | 03-10-2016 |
20160069921 | SYSTEMS AND METHODS FOR MULTI-ANALYSIS - Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. | 03-10-2016 |
20160091520 | Automatic Apparatus of Screening Disease/Cancer in Vitro - An automatic apparatus is provided for screening disease/cancer in vitro. The apparatus comprises a filling device; a gripping device at a side of the filling device; a carrying platform correspondingly set under the filling device and the gripping device; a containing device on the carrying platform; at least two receiving slots on the carrying platform; a placing device on the carrying platform; a shaking device on the carrying platform; and a detecting device on the carrying platform. Thus, the apparatus is provided for molecular biological researches, biochemical examinations, radioimmunoassay and drug developments with reduced human labor, saved operating time, avoided experimental errors and enhanced experimental accuracy and efficiency. | 03-31-2016 |
20160161410 | Multiview Light-Sheet Microscopy - A live biological specimen is imaged by generating a plurality of light sheets; directing the plurality of light sheets along an illumination axis through the biological specimen such that the light sheets spatially and temporally overlap within the biological specimen along an image plane, and optically interact with the biological specimen within the image plane; and recording, at each of a plurality of views, images of the fluorescence emitted along a detection axis from the biological specimen due to the optical interaction between the light sheets and the biological specimen. The temporal overlap is within a time shift that is less than a resolution time that corresponds to a spatial resolution limit of the microscope. | 06-09-2016 |
20180024070 | LUMINOMETER APPARATUS | 01-25-2018 |
20190143330 | APPARATUS FOR FORMING LIQUID FLOW INCLUDING BIOLOGICAL PARTICLES, AND TREATMENT APPARATUS | 05-16-2019 |