Class / Patent application number | Description | Number of patent applications / Date published |
422045000 | Oxygenator | 64 |
20090175762 | OXYGENATOR UNIT AND OXYGENATOR APPARATUS - An oxygenator unit includes a venous reservoir, a centrifugal pump, an oxygenator, a connection part for connecting the reservoir and the pump, a connection part for connecting the pump and the oxygenator, and a unit frame. The unit frame includes a reservoir receiving part, a pump receiving part provided at the position under a blood outlet of the venous reservoir disposed at the reservoir receiving part, and an oxygenator receiving part provided at the position in the vicinity of the blood outlet of the centrifugal pump disposed on the pump receiving part. The reservoir is disposed at the reservoir receiving part, the pump is disposed at the pump receiving part; and the oxygenator is disposed at the oxygenator receiving part, and they are held by the unit frame, resulting in a unit. | 07-09-2009 |
20100143190 | SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING OCCLUSION DETECTION CAPABILITIES - This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid via an extracorporeal circuit. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The controller is capable of detecting occlusions in the extracorporeal circuit and responding to different occlusion conditions to prevent forced shutdown/re-priming of the circuit. | 06-10-2010 |
20100143191 | SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING A DUAL-FUNCTION POWER SWITCH MECHANISM - This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid. An apparatus adapted for connecting with a gas tank is included in the system for gas tank hook-up. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The system has a power supply for providing electrical power to the system, and a switching mechanism coupled to the power supply and gas tank for synchronized switching of the power supply and the gas tank between an ON state and an OFF state. | 06-10-2010 |
20100143192 | METHOD AND DEVICE FOR COMBINED DETECTION OF BUBBLES AND FLOW RATE IN A SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS - This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The system includes a combination bubble detector/flow meter that uses a single ultrasonic probe for detecting bubbles and measuring fluid flow rate. | 06-10-2010 |
20100272604 | Radial Design Oxygenator with Heat Exchanger and Integrated Pump - Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises at least one integrated pump that is provided in a core of the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the at least one integrated pump and between which blood from the at least one integrated pump can move radially outward; an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and through which blood from the heat exchanger can move radially outward; and an optional filter arranged around the oxygenator and through which blood from the oxygenator can move radially outward before exiting the apparatus through the outlet. | 10-28-2010 |
20110158847 | Microfluidic Device Facilitating Gas Exchange, and Methods of Use and Manufacture Thereof - The invention provides systems and methods for exchanging gas in a microfluidic device, and methods for preparing such microfluidic devices. The systems and methods can be used to transfer oxygen to blood to assist lung function in a patient. | 06-30-2011 |
20110268608 | OXYGENATOR WITH INTEGRATED ARTERIAL FILTER - An oxygenator combines, in a single structure, a heat exchanger, a gas exchanger and an arterial filter. Such an oxygenator permits fewer fluid connections and thus may simplify an extracorporeal blood circuit, including a heart-lung machine and a blood reservoir, in which it is used. In some cases, the oxygenator may be configured to include multiple purge ports for purging bubbles both before and after filtering the blood. | 11-03-2011 |
20120076690 | Treating Heart Tissue - Some embodiments of a system or method for treating heart tissue can include a catheter device that provides a user with the ability to perform a number of heart treatment tasks (before, during, and after a cardiac surgery or a percutaneous coronary intervention). In particular embodiments, the catheter device can be used to (i) precondition heart muscle tissue before the heart is isolated from the circulatory system, (ii) deliver cardioplegia into the coronary sinus during the cardiac surgery when the heart is isolated from the circulatory system, and (iii) control the blood flow through the heart after the heart is reconnected with the circulatory system. In some embodiments, the catheter device can perform some or all of: (i) intermittently occluding the coronary sinus, (ii) delivering a treatment fluid into the coronary sinus, and (iii) monitoring a flow rate of blood passing from the coronary sinus to the right atrium. | 03-29-2012 |
20120076691 | Treating Heart Tissue - Some embodiments of a system or method for treating heart tissue can include a catheter device that provides a user with the ability to perform a number of heart treatment tasks (before, during, and after a cardiac surgery or a percutaneous coronary intervention). In particular embodiments, the catheter device can be used to (i) precondition heart muscle tissue before the heart is isolated from the circulatory system, (ii) deliver cardioplegia into the coronary sinus during the cardiac surgery when the heart is isolated from the circulatory system, and (iii) control the blood flow through the heart after the heart is reconnected with the circulatory system. In some embodiments, the catheter device can perform some or all of: (i) intermittently occluding the coronary sinus, (ii) delivering a treatment fluid into the coronary sinus, and (iii) monitoring a flow rate of blood passing from the coronary sinus to the right atrium. | 03-29-2012 |
20130017119 | DUAL CHAMBER BLOOD RESERVOIRAANM Silvestri; ClaudioAACI Quarantoli Mirandola (MO)AACO ITAAGP Silvestri; Claudio Quarantoli Mirandola (MO) ITAANM Tommasi; GabrieleAACI CavezzoAACO ITAAGP Tommasi; Gabriele Cavezzo IT - A blood reservoir may be used in combination with other elements such as a heart lung machine (HLM), oxygenator, heat exchanger, arterial filter and the like to form an extracorporeal blood circuit that may be employed in a procedure such as a bypass procedure. The blood reservoir may be configured to receive, filter and store blood from a number of sources including vent blood (from within the heart), venous blood (from a major vein), purge blood (from a sampling line) and cardiotomy or suction blood (from the surgical field). | 01-17-2013 |
20130078144 | LIQUID COLLECTION CONTAINER AND EXTRACORPOREAL CIRCUIT - A liquid collection bag is used as a part of an extracorporeal circuit and is connected via a tube to a storage container containing a priming solution. The collection container collects the priming solution from the storage container by a pressure differential between the pressure inside the collection container and the pressure inside the storage container. The liquid collection container is a flexible bag body having a partition part dividing the inside of the bag body into a first space and a second space. In addition, a communication part communicates the first space with the second space. | 03-28-2013 |
20130094996 | CARDIOPULMONARY BYPASS OR CPB MONITORING TOOL - A cardiopulmonary bypass or CPB monitoring tool includes: a preoperative information module; a preoperative calculation module able to estimate a body surface area, blood volume, and theoretical weight; a priming module able to determine priming constitution, volume and flow to achieve a hemodilution target; an operation risk module for calculating operation risk; a drug calculation module able to determine medication doses; a timer module with timers that can be activated during operation; a data collection module with an interface and drivers enabling data collection from a wide variety of extracorporeal pumps and oxygenators during operation; an events module with retroactive manipulation of the time of an event; a printing report generation module; a graphic user interface; and a configuration module. | 04-18-2013 |
20130101464 | EXTRACORPOREAL PHOTODYNAMIC BLOOD ILLUMINATION (IRRADIATION) FOR THE TREATMENT OF CARBON MONOXIDE POISONING - Treatment of carbon monoxide poisoning of a body by removal of a portion of the blood from the body, placing the portion in an exposure cell, exposing the portion in the cell to light of wave length and intensity that causes dissociation of carbon monoxide from hemoglobin, and returning the portion to the body. The intensity and wave length of the light is sufficient to dissociate a therapeutically-effective amount of carbon monoxide from the hemoglobin in the blood. The blood is circulated from and to the body through a concentric double lumen cannula. The wave lengths of the light are 540 and/or 570 nanometers. The cell exposes the blood to at least 9.5 Joules of dissociative light per milliliter of blood, and least 9.5 Watts of dissociative light per milliliter of blood per second. Oxygen is provided to, and the dissociated carbon monoxide is removed from the system. | 04-25-2013 |
20140050616 | MONITORING SYSTEM FOR CARDIAC SURGICAL OPERATIONS WITH CARDIOPULMONARY BYPASS - A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device inserted inside the arterial or venous line of the heart-lung machine to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value. | 02-20-2014 |
20140079590 | PERFUSION SYSTEM WITH RFID FEATURE ACTIVATION - The disclosure pertains to a perfusion system that is easy to set-up, use and monitor during a bypass procedure. In some embodiments, the disclosure pertains to a perfusion system in which at least some of the disposable components used with the perfusion system are configured to be able to communicate set-up and/or operational parameters to the perfusion system in order to unlock further functionality within the perfusion system. | 03-20-2014 |
20140099235 | BLOOD PERFUSION SYSTEM - An extracorporeal blood perfusion system includes a disposable assembly and a control unit having a control interface region. The interface region includes pump assemblies for selective pumping of venous blood, arterial blood, cardioplegia solution, suctioned blood and blood removed from the left ventricle. Valve assemblies control the flow of fluids through the assembly and to/from the patient and sensors monitor various fluid parameters including temperature and pressure within the various fluid circuits. The user interface is a functional screen interface for effecting the operation of the control unit and valve assemblies. The screen interface may be a touch screen having objects that corresponds to the component interface region. The display may be selectively controlled to provide graphic depictions of disposable assembly components with corresponding narrative instructions. | 04-10-2014 |
20140219867 | Blood Treatment Method Adapted to at Least Partially Eliminate the Carbon Dioxide Content and Related Device - A blood treatment method is described that is adapted to at least partially eliminate the carbon dioxide content of the type comprising a step of drawing a blood flow. Advantageously according to the invention, the method further comprises the steps of: acidifying the blood flow with transformation of the related blood bicarbonate content into gaseous carbon dioxide; and eliminating the gaseous carbon dioxide content by means of a pressure gradient. | 08-07-2014 |
20140234166 | Exsanguination preventing device - In one embodiment, an exsanguination preventing device includes a collection container having an inlet configured to receive blood from a patient and an outlet configured to discharge the blood; a pump operatively coupled to the collection container; a conduit fluidly coupled to the collection container, which receives the blood from the collection container, the blood being moved by the pump; and an insertion device, which delivers the blood from the conduit to a bodily part of the patient. The collection container is configured to be sealingly coupled to a wound on the patient and air entrapped within the exsanguination preventing device is removed by an air removal system, such to prevent unwanted discharge of air into the bodily part of the patient. All the components of the exsanguination preventing device are sized such to make it portable in a pocket of a garment or backpack of a soldier. | 08-21-2014 |
20140271357 | CPB System With Fluid Volume Control - In an extracorporeal blood circuit system or a machine configurable in such a circuit, a bag blood reservoir has an infusion port at the upper end of the bag, an outlet port at the lower end of the bag, an inlet port at the lower end of the bag, and an IV port at the lower end of the bag. A split line is connected to the infusion port, having a first branch line connected to a source makeup fluid into the reservoir and a second branch line that evacuates from the reservoir. An air detector and a vent controller automatically configure a venting path in which the inlet lines to the pump and to the blood reservoir are open such that air rises to the upper end of the blood reservoir from which it can be vented through the infusion port into the air evacuation line. | 09-18-2014 |
20140271358 | CPB Pump System With Double Y Tubing - A system and associated tubing set for installation on the panel of extracorporeal circuit, including a pump tubing unit featuring a disposable pump. Two inlet line branches are fluidly connected to the pump inlet and two outlet line branches are fluidly connected to the pump outlet. The free ends of one inlet branch and one outlet branch carry a Colder type connector and a clamp between the pump and the respective Colder connectors. A blood reservoir unit has a support plate mountable to the panel, which carries a blood bag having an inlet line with a free end and Colder connector and an outlet line with free end and Colder connector. | 09-18-2014 |
20150030502 | ARRANGEMENT WITH A BLOOD PUMP AND PUMP CONTROL UNIT - An arrangement for extracorporeal life support is further developed in such a way that a pump actuating signal produces a wave-like surging and subsiding pump output for a pulsatile flow. The pump is preferably a non-occlusive blood pump, such as a diagonal pump, for example. In a preferred variant of embodiment the control signal is provided by an ECG. This allows the diastolic pressure to be increased in order to improve the oxygen balance of the heart muscle. | 01-29-2015 |
20150290385 | EXTRACORPOREAL PHOTODYNAMIC BLOOD ILLUMINATION (IRRADIATION) FOR THE TREATMENT OF CARBON MONOXIDE POISONING - Treatment of carbon monoxide poisoning of a body by removal of a portion of the blood from the body, placing the portion in an exposure cell, exposing the portion in the cell to light of wave length and intensity that causes dissociation of carbon monoxide from hemoglobin, and returning the portion to the body. The intensity and wave length of the light is sufficient to dissociate a therapeutically-effective amount of carbon monoxide from the hemoglobin in the blood. The blood is circulated from and to the body through a concentric double lumen cannula. The wave lengths of the light are 540 and/or 570 nanometers. The cell exposes the blood to at least 9.5 Joules of dissociative light per milliliter of blood, and least 9.5 Watts of dissociative light per milliliter of blood per second. Oxygen is provided to, and the dissociated carbon monoxide is removed from the system. | 10-15-2015 |
20160000986 | BLOOD OXYGENATION SYSTEM - A blood oxygenation system which prevents transmigration of blood to gaseous oxygen circuitry. The system includes a blood circuit, an oxygen supply circuit, an oxygen-blood interface in which gaseous oxygen is absorbed into the blood, and an oxygen disposal circuit for disposing of unused oxygen. The oxygen-blood interface is arranged to prevent transmigration of blood into the oxygen circuit. The blood circuit includes a pump and a blood de-aerator. The oxygen supply circuit includes an oxygen supply, an ozone generator, and an ozone destructor. A silica gel trap in the oxygen disposal circuit separates O | 01-07-2016 |
20160136347 | AMBULATORY LUNG ASSIST DEVICE WITH IMPLANTED BLOOD PUMP AND OXYGENATOR - The present disclosure provides a system for oxygenating blood. The system may include an implantable blood pump that may draw a supply of blood from the circulatory system of a mammalian subject, such as a human being. The blood pump may provide the supply of blood to an adaptor, where the supply of blood may be supplied to either or both of a first branch or second branch. The first branch may lead to an external blood oxygenator. The oxygenator may oxygenate the blood, and the blood may be returned to the circulatory system of the mammalian subject. The second branch may bypass the oxygenator and may connect to the circulatory system of the mammalian subject. In this regard, while the blood is supplied to the second branch, the oxygenator may be disconnected and blood may be prevented from entering the first branch. | 05-19-2016 |
422046000 | Including integral heat-exchange means | 18 |
20090081079 | Blood/Air Mass Exchange Apparatus - There is provided a mass exchange apparatus ( | 03-26-2009 |
20090087342 | DEVICE AND METHODS FOR PROCESSING BLOOD IN EXTRACORPOREAL CIRCULATION - A device for treating blood in an extracorporeal blood circuit, the device including a centrifugal pump provided with a transparent enclosure that is connected, by means of an inlet duct, to the outlet of a venous reservoir, the venous reservoir having an inlet that is connected to receive blood from a patient. The transparent enclosure of the pump is connected monolithically to the base of a structure that comprises a heat exchanger and an oxygenator. The structure also supports monolithically, at the peripheral region, an arterial filter that receives the blood in output from the oxygenator and is provided with a connector for coupling to an arterial line for return of the blood to the patient. | 04-02-2009 |
20100272605 | RADIAL DESIGN OXYGENATOR WITH HEAT EXCHANGER AND PUMP - Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises: at least one pump that is provided in a core of the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the at least one pump and between which blood from the at least one pump can move radially outward; and an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and through which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet. | 10-28-2010 |
20100272606 | RADIAL FLOW OXYGENATOR/HEAT EXCHANGER - Described is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit comprising: an inlet mandrel that is configured such that the blood moves radially outward from the inlet mandrel through the openings in a radial direction; a heat exchanger arranged around the inlet mandrel, wherein blood can move radially outward with the transfer of heat to or from the blood; an oxygenator arranged around the heat exchanger, wherein blood can move from the heat exchanger radially outward with the transfer of oxygen into the blood; and a housing that houses the inlet mandrel, the heat exchanger and the oxygenator, and that comprises a blood inlet in communication with the inlet mandrel in order to allow blood to enter the apparatus from the patient, and a blood outlet in communication with the oxygenator in order for blood to exit the apparatus, wherein the blood outlet is located in the housing radially outward from the inlet. | 10-28-2010 |
20100272607 | RADIAL DESIGN OXYGENATOR WITH HEAT EXCHANGER AND INLET MANDREL - Described is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit, the apparatus having an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus, the apparatus comprising: a core in communication with the inlet such that blood from a patient can be supplied to the core, the core comprising a first element and a second element that interfit to define openings, wherein the elements and the openings together enhance flow of blood from the patient radially outward from the core; a heat exchanger that is arranged about the core and through which blood from the core can move radially outward; and an oxygenator that is arranged about the heat exchanger and through which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet. | 10-28-2010 |
20100290947 | MEDICAL HEAT EXCHANGER, MANUFACTURING METHOD THEREOF AND ARTIFICIAL LUNG DEVICE - A medical heat exchanger includes a thin tube bundle | 11-18-2010 |
20110268609 | OXYGENATOR WITH INTEGRATED ARTERIAL FILTER INCLUDING FILTER FRAME - An oxygenator combines, in a single structure, a heat exchanger, a gas exchanger, an arterial filter, and a filter frame. Such an oxygenator permits fewer fluid connections and thus may simplify an extracorporeal blood circuit, including a heart-lung machine and a blood reservoir, in which it is used. In some embodiments, the oxygenator may be configured to include multiple purge ports for purging bubbles both before and after filtering the blood. | 11-03-2011 |
20110300020 | OXYGENATOR - An oxygenator that inhibits or prevents bubbles in blood from exiting through a blood outlet includes an oxygenator part which performs gas exchange on blood and a heat exchanging part which performs heat exchange on the blood. The oxygenators part has a housing that is generally in a rectangular parallelepiped form, with a hollow fiber membrane bundle positioned in the housing. The hollow fiber membrane bundle is formed by a multiplicity of hollow fiber membranes adapted to perform gas exchange. Blood flows along a blood passage comprised of gaps between the hollow fiber membranes and contacts the surface of the hollow fiber membranes where gas exchange occurs with gas flowing through the lumens of the hollow fiber membranes. In addition, a filter member is arranged on a downstream side of the hollow fiber membrane bundle so that bubbles present in the blood are caught by the filter member. | 12-08-2011 |
20120294761 | BLOOD PROCESSING UNIT WITH CROSS BLOOD FLOW - A blood processing apparatus may include a heat exchanger and a gas exchanger. The heat exchanger may be configured to provide a cross-flow or radially directed blood flow through the heat exchanger. | 11-22-2012 |
20120308434 | HEAT EXCHANGER AND HEAT-EXCHANGER-INTEGRATED OXYGENATOR - A plurality of heat transfer pipes have a circumferential portion arranged at a short distance from an inner surface of a heat exchanger case while they are bundled to form a pipe group and a first bowstring-shaped portion which retracts toward a center in a direction of cylinder diameter from an arc formed by the circumferential portion. The plurality of bundled heat transfer pipes are loaded in the exchange case such that the first bowstring-shaped portion and an inner surface of the heat exchange case on a side where a heat exchange medium inlet port is attached are opposed to each other. By making a flow of a heat exchange medium to each heat transfer pipe uniform, a heat exchanger capable of obtaining high heat exchange performance is obtained. | 12-06-2012 |
20120321512 | HEAT EXCHANGER AND HEAT-EXCHANGER-INTEGRATED OXYGENATOR - A heat exchanger includes a case, a bottom member and a plurality of heat transfer pipes (a pipe group) loaded in the heat exchanger case, in which blood flows from one end through the bottom member. The bottom member has an annular wall, a bottom surface, and a blood inlet port. The bottom surface is opposed to one end of the heat transfer pipe. The bottom surface includes a groove portion and a raised bottom portion provided on each of opposing end sides of the groove portion. The raised bottom portion is inclined such that a distance between the raised bottom portion on a side where the blood inlet port is provided and one end of the heat transfer pipe is smaller than a distance between the raised bottom portion opposite to the side where the blood inlet port is provided and one end of the heat transfer pipe. | 12-20-2012 |
20130142695 | OXYGENATOR WITH INTEGRATED ARTERIAL FILTER INCLUDING FILTER FRAME - An oxygenator combines, in a single structure, a heat exchanger, a gas exchanger, an arterial filter, and a filter frame. Such an oxygenator permits fewer fluid connections and thus may simplify an extracorporeal blood circuit, including a heart-lung machine and a blood reservoir, in which it is used. In some embodiments, the oxygenator may be configured to include multiple purge ports for purging bubbles both before and after filtering the blood. | 06-06-2013 |
20130142696 | BLOOD PROCESSING UNIT WITH MODIFIED FLOW PATH - A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path. | 06-06-2013 |
20130209314 | DUAL OUTLET OXYGENATOR FOR TREATING BLOOD IN AN EXTRACORPOREAL BLOOD CIRCUIT - An apparatus for oxygenating blood including a housing and an oxygenator bundle. The housing defines a primary chamber, a blood inlet port open to the primary chamber, and a blood outlet region. The outlet region includes a blood outlet port, an outlet chamber open to the outlet port, and a partition. The partition establishes spaced apart, first and second passageways from the primary chamber to the outlet chamber. The oxygenator bundle is disposed within the primary chamber. A blood flow path is formed from the blood inlet port, through the oxygenator bundle and to the blood outlet port, and includes first and second outlet flow paths within the outlet chamber via the first and second passageways, respectively. The first and second outlet blood flow paths merge at the blood outlet port. A dual port blood outlet is created, increasing mixing of blood immediately upstream of the outlet port. | 08-15-2013 |
20130272924 | Surgical Heating and Cooling System and Devices and Methods for the Use Thereof - A modular cooling-heating system for use in the controlled delivery of temperature-controlled fluids to a heat exchanger associated with the blood of a patient undergoing a medical procedure is described, wherein the cooling-heating system uses adaptive temperature control protocols. | 10-17-2013 |
20140030146 | OXYGENATOR - An oxygenator includes a housing; a hollow fiber membrane layer that is stored in the housing and has multiple integrated hollow fiber membranes with a gas exchange function; a gas inlet portion and a gas outlet portion that are provided on the upstream and downstream of gas passages in lumens of the hollow fiber membranes, respectively; and a blood inlet portion and a blood outlet portion that are provided on the upstream and downstream of blood passages outsides of the hollow fiber membranes, respectively. The hollow fiber membranes in the hollow fiber membrane layer are fixed relative to each other at one end portion and the other end portion thereof. Conditions 30≦ε60 and OD≦4.5×ε are met where ε [μm] is an average separation distance between the adjacent hollow fiber membranes at a fixed portion of the hollow fiber membrane layer and OD [μm] is the outer diameter of the hollow fiber membrane. | 01-30-2014 |
20140050617 | DUAL OUTLET OXYGENATOR FOR TREATING BLOOD IN AN EXTRACORPOREAL BLOOD CIRCUIT - An apparatus for oxygenating blood including a housing and an oxygenator bundle. The housing defines a primary chamber, a blood inlet port open to the primary chamber, and a blood outlet region. The outlet region includes a blood outlet port, an outlet chamber open to the outlet port, and a partition. The partition establishes spaced apart, first and second passageways from the primary chamber to the outlet chamber. The oxygenator bundle is disposed within the primary chamber. A blood flow path is formed from the blood inlet port, through the oxygenator bundle and to the blood outlet port, and includes first and second outlet flow paths within the outlet chamber via the first and second passageways, respectively. The first and second outlet blood flow paths merge at the blood outlet port. A dual port blood outlet is created, increasing mixing of blood immediately upstream of the outlet port. | 02-20-2014 |
20140154137 | APPARATUS FOR MASS- AND/OR ENERGY-TRANSFER BETWEEN TWO MEDIA - The invention relates to an apparatus and a process for mass- and/or energy-transfer between two media, in particular between blood and a gas/gas mixture, having a chamber ( | 06-05-2014 |
422048000 | Membrane | 22 |
20080199357 | Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system - The invention relates to an integrated centrifugal blood pump-oxygenator ( | 08-21-2008 |
20090098017 | NANOPOROUS MEMBRANE EXCHANGER - The invention is a nanoporous membrane exchanger. | 04-16-2009 |
20100111761 | PROCESS OF SYNTHESIS ASYMMETRIC POLYURETHANE BASED MEMBRANES WITH HEMOCOMPATIBILITY CHARACTERISTICS AND MEMBRANES OBTAINED BY SAID PROCESS - The present invention refers to polymeric membranes and its synthesis with combination of innovative characteristics at the level of the bi-soft segment polyurethane material and at the level of the structure as integral asymmetric membranes. The hemocompability properties—non-hemolytic, non-thrombogenic and no platelet adhesion—combined with the high fluxes of permeation of O | 05-06-2010 |
20100135852 | OXYGENATOR OF A HOLLOW FIBER MEMBRANE TYPE - The invention provides an oxygenator of a hollow fiber membrane type where a plurality of hollow fiber membranes are received in a housing, wherein at least a part of the regions of the hollow fiber membranes to contact blood during use is coated with a water-insoluble (meth)acrylate copolymer in which a hydrophobic (meth)acrylate is copolymerized with a hydrophilic (meth)acrylate at a molar ratio of (50 to 90):(50 to 10). | 06-03-2010 |
20110129389 | EXTRA-CORPOREAL MEMBRANE OXYGENATION CONTROL - A method may include obtaining information representing at least one of a concentration of carbon dioxide in a patient's blood, a concentration of oxygen in the patient's blood or a pH value of the patient's blood. The method may also include setting an initial carbon dioxide tension in a membrane oxygenator of an extra-corporeal membrane oxygenation (ECMO) system based on the obtained information. | 06-02-2011 |
20130004369 | ARRANGEMENT WITH A BLOOD PUMP AND A GAS EXCHANGER FOR EXTRACORPOREAL MEMBRANE OXYGENATION - The invention relates to an arrangement having a blood pump and a gas exchanger for extracorporeal membrane oxygenation. According to the invention, the blood pump is designed as a pulsatile blood pump and is arranged with the gas exchanger in the same housing. The pulsatile blood pump and the gas exchanger are preferably connected to the same gas source so that the blood pump can be pneumatically driven. The novel ECMO system has a simple design, is flexible, and in particular can be used directly on the patient. | 01-03-2013 |
20130094997 | EVEN PERFUSION PUMP-INTEGRATED BLOOD OXYGENATOR - A blood oxygenator includes an integral pneumatic pump disposed substantially within a housing thereof, an inlet blood flow redirector, and an outflow blood collector. An atrium provided at an inlet of the oxygenator promotes even delivery of blood to the oxygenator. In use, the oxygenator provides an even dispersion of blood therethrough, establishing even perfusion and reducing areas of stagnant blood flow. | 04-18-2013 |
20130101465 | DEVICE FOR TREATING BLOOD IN AN EXTRACORPOREAL CIRCULATION - A device for oxygenating blood during extracorporeal circulation includes a box-like body having a first end and a second end opposite thereto and defining therebetween a treatment chamber with an inner surface. The device further includes, in the treatment chamber, at least one exchange unit having at least one flat diaphragm that is impervious to blood and has a major axis and a minor axis. The diaphragm has a winding of hollow microporous fibers. The device further includes an inlet port and an outlet port axially aligned with one another in an alignment direction. A compartment is provided for accumulation and delivery of blood to be treated, another compartment for collecting treated blood, the compartments being located downstream of the inlet port and upstream of the outlet port, between the exchange unit and the inner surface of the treatment chamber. The diaphragm is disposed with the major axis parallel to the alignment direction. | 04-25-2013 |
20130343953 | TREATMENT OF FLUID-BORNE CANCER CELLS - Provided are devices, device systems, and methods to intercept and kill fluid borne cancer cells to slow or prevent metastases. | 12-26-2013 |
20130343954 | COMPACT INTEGRATED BLOOD PUMP OXYGENATOR OR GAS TRANSFER DEVICE WITH HYDROGEL IMPELLER PACKING MATERIAL AND ROLLOVER IMPELLER OUTLET - An integrated blood pump oxygenator comprises an an impeller housing supporting an impeller; with an annular hydrogel impeller packing material adjacent the bearings and around the shaft of the impeller. The oxygenator including a rollover outlet in the form of an annular chamber extending around a center pump housing member; and further including an annular chamber within an annular array of hollow fiber membranes in fluid communication with the annular chamber extending from the impeller around the center pump housing; wherein the annular chamber provides substantially perpendicular radial outward cross flow across the membranes. | 12-26-2013 |
20140030147 | EXTRACORPOREAL CIRCUIT FOR REMOVING CO2 FROM BLOOD - An extracorporeal circuit for removing CO | 01-30-2014 |
20140030148 | EXTRACORPOREAL CIRCUIT FOR REMOVING CO2 FROM BLOOD - An extracorporeal circuit for removing CO | 01-30-2014 |
20140030149 | OXYGENATOR AND EXTRACORPOREAL CIRCUIT - An oxygenator includes: a housing; a hollow fiber membrane bundle stored in the housing and having multiple integrated hollow fiber membranes with a gas exchange function; a gas inlet portion and a gas outlet portion provided on the upstream and downstream of gas passages in lumens of the hollow fiber membranes, respectively; a blood inlet portion and a blood outlet portion provided on the upstream and downstream of blood passages outside the hollow fiber membranes, respectively; a first filter member provided on the hollow fiber membrane bundle in contact with a blood outlet portion side surface so as to cover substantially the entire surface and has a function to catch bubbles in blood; and a second filter member that is separated from the first filter member, positioned between the first filter member and the blood outlet portion, and has a function to catch bubbles in blood. | 01-30-2014 |
20140037500 | Integrated Centrifugal Blood Pump-Oxygenator, an Extracorporeal Life Support System and a Method of De-Bubbling and Priming an Extracorporeal Life Support System - An integrated centrifugal blood pump-oxygenator ( | 02-06-2014 |
20140050618 | APPARATUS FOR MAKING EXTRACORPOREAL BLOOD CIRCULATION AVAILABLE - The present invention relates to an apparatus for making extracorporeal blood circulation available, in particular a heart-lung machine, comprising a venous connection and an arterial connection, between which a blood reservoir, a blood pump and a bubble detector for the detection of air bubbles are provided, with, downstream of the bubble detector, an arterial line leading to the arterial connection via an arterial clamp and a bypass leading via a bypass clamp back into the blood reservoir which is connected to a pump extracting air from the blood reservoir. In addition, the present invention relates to a method of operating such an apparatus. | 02-20-2014 |
20140065016 | PARACORPOREAL RESPIRATORY ASSIST LUNG - A paracorporeal respiratory assist lung is configured with an annular cylindrical hollow fiber membrane (fiber bundle) that is rotated at rapidly varying speeds. Fluid (for example, blood) is introduced to the center of the device and is passed radially through the fiber bundle. The bundle is rotated at rapidly changing velocities with a rotational actuator (for example, a motor or magnetic coupling). The rotation of the fiber bundle provides centrifugal kinetic energy to the fluid giving the device pumping capabilities and may create Taylor vortexes to increase mass transfer. Rotation of the fiber bundle increases the relative velocity between the fluid and the hollow fibers and increases the mass transfer. The porosity of the fiber bundle may be varied to enhance gas exchange with the blood. Alternatively, a rotating core may be used with a stationary fiber bundle. | 03-06-2014 |
20140255253 | ARTIFICIAL PLACENTA - An artificial placenta oxygenating device for use with an infant is provided. The device comprises a first layer comprising a gas permeable membrane; and a second layer comprising a vascular network that permits circulation of fluid therethrough, wherein a portion of the gas permeable membrane is attached to and covers the vascular network, wherein the vascular network comprises an inlet that permits fluid flow into the vascular network and an outlet that permits fluid to flow out of the vascular network and wherein the inlet and outlet are positioned so that fluid flows through the vascular network and in contact with the gas permeable membrane to permit gas exchange to occur. Assemblies comprising a plurality of single artificial placenta devices is also provided. | 09-11-2014 |
20140294672 | NITRIC OXIDE DELIVERY DEVICES - An example of a nitric oxide delivery device includes a medium, a working electrode in contact with the medium, and a reference/counter electrode in contact with the medium and electrically isolated from the working electrode. The medium includes a source of nitrite ions and a Cu(II)-ligand complex. A nitric oxide permeable material separates the medium from an external environment that is to contain blood. | 10-02-2014 |
20150010433 | PRODUCTION METHOD FOR MEDICAL INSTRUMENT AND MEDICAL INSTRUMENT - A production method for a medical instrument includes a plurality of integrated hollow fiber membrane producing a base material forming a cylindrically-shaped body. Each of the hollow fiber membranes sequentially passes through a first point, a second point, a third point, a fourth point, and a fifth point that are set on a core member. In an outward path heading toward the third point from the second point, the hollow fiber membrane reaches the third point from the second point at the shortest distance while being wound in the circumferential direction of the core member. Moreover, in a homeward path heading toward the fifth point from the fourth point, the hollow fiber membrane reaches the fifth point from the fourth point at the shortest distance while being wound in the circumferential direction of the core member in the same direction as in the case of the outward path. | 01-08-2015 |
20150010434 | MEDICAL INSTRUMENT - An Oxygenator as a medical instrument includes at least one first hollow fiber membrane layer comprised of a plurality of integrated first hollow fiber membranes, and forms a shape of a cylindrical body as a whole, and at least one second hollow fiber membrane layer disposed at the outer circumferential side of the first hollow fiber membrane layer in a state of being concentric with the first hollow fiber membrane layer, has a plurality of integrated second hollow fiber membranes, and forms a shape of a cylindrical body as a whole. Moreover, each of the first hollow fiber membranes is wound around a central axis, and each of the second hollow fiber membranes is wound around a central axis. The number of times the second hollow fiber membranes are wound is smaller than the number of times the first hollow fiber membranes are wound. | 01-08-2015 |
20160015881 | CIRCULATION APPARATUS AND METHOD FOR CONTROLLING SAME - An artificial lung in a circulation apparatus can be monitored and be maintained in a safe condition without manual assistance. As an extracorporeal circulation mode starts, it is determined first whether or not gas exchange of the artificial lung is carried out within a normal range, based on oxygen concentration which is detected by an oxygen sensor positioned at a downstream place in the artificial lung. If the gas exchange is carried out within the normal range, an estimated value for gas supply volume of a gas blender is maintained. When oxygen concentration exceeding the normal range is detected, the gas blender is controlled so as to revise the gas supply volume downward. In addition, when oxygen concentration falls below the normal range, the gas blender is controlled so as to revise the gas supply volume upward. | 01-21-2016 |
20160095969 | OXYGENATOR MODULE, OXYGENATOR AND PRODUCTION METHOD - An oxygenator module for gas exchange between blood and a gas in an extracorporeal lung support system, with several layers of semipermeable, gas-perfusable hollow fibers, wherein the hollow fibers of one of the layers are oriented at an angle of rotation about a central longitudinal axis of the oxygenator module with respect to the hollow fibers of another one of the layers, and with a potting which extends along the central longitudinal axis and in which the hollow fibers are fixed, wherein the potting defines a cavity that extends along the central longitudinal axis and in which the hollow fibers are arranged and which is blood-perfusable in the direction of the central longitudinal axis, wherein the potting has an essentially circular inner sheath surface that limits the cavity radially outward: as well as a method for producing the oxygenator module. | 04-07-2016 |