Entries |
Document | Title | Date |
20080197026 | TRANSITION METAL COMPLEXES WITH (PYRIDYL)IMIDAZOLE LIGANDS - Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme-based electrochemical sensors. The transition metal complexes include substituted or unsubstituted (pyridyl)imidazole ligands. Transition metal complexes attached to polymeric backbones are also described. | 08-21-2008 |
20080245675 | METHOD OF ALTERING THE SENSITIVITY AND/OR SELECTIVITY OF A CHEMIRESISTOR SENSOR - The present invention relates to a method of altering the sensitivity and/or selectivity of a chemiresistor sensor, to a sensor and a sensor array produced by such method. | 10-09-2008 |
20090020438 | ELECTROCHEMICAL CELL - The present invention relates to electrochemical cells including a first working electrode | 01-22-2009 |
20090050492 | Nanoporous silicon-based electrochemical nucleic acid biosensor - A method and biosensor device for detecting single strand target nucleic acid by cyclic voltammetry is described. A porous silicon chip is linked to bound DNA probe complementary to the target nucleic acid. The device is particularly useful for detecting microorganisms and viruses that may be pathogenic or cancer genes, however any target nucleic acid can be detected by using a specific DNA probe. | 02-26-2009 |
20090071848 | CERIUM OXIDE NANOPARTICLE REGENERATIVE FREE RADICAL SENSOR - An electrochemical sensor system for sensing free radicals or materials which generate free radicals in solution includes a working electrode coated with a plurality of cerium oxide nanoparticles and a counter electrode. A solution to be analyzed provides electrolytes to electrically couple the working electrode to the counter electrode. Electronics are connected to at least one of the working and counter electrodes for measuring and amplifying an electrical current signal generated by reduction or oxidation occurring at the working electrode, wherein in a presence of free radicals an electrical current signal flows between the working electrode and the counter electrode. The system can be used to sense the presence of hydrogen peroxide. | 03-19-2009 |
20090211922 | ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS, APPARATUS FOR ELECTROCHEMICAL MEASUREMENTS HAVING THE ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS, AND METHOD OF THE QUANTITATIVE DETERMINATION OF A TARGET SUBSTANCE USING THE ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS - An electrode plate for electrochemical measurements capable of measuring the concentration of a target substance included in a sample solution with favorable accuracy and high sensitivity is provided | 08-27-2009 |
20090242428 | METHOD FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A LIQUID SAMPLE USING SMALL VOLUME SAMPLES AND FAST TEST TIMES - Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.5 μl and test times within ten seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action. | 10-01-2009 |
20100012527 | Small Volume In Vitro Analyte Sensor - A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In addition, a second electron transfer agent, such as an enzyme, can be added to facilitate the electrooxidation or electroreduction of the analyte. The redox mediator is typically a redox compound bound to a polymer. The preferred redox mediators are air-oxidizable. | 01-21-2010 |
20100012528 | Small Volume In Vitro Analyte Sensor - A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In addition, a second electron transfer agent, such as an enzyme, can be added to facilitate the electrooxidation or electroreduction of the analyte. The redox mediator is typically a redox compound bound to a polymer. The preferred redox mediators are air-oxidizable. | 01-21-2010 |
20100018877 | Small Volume In Vitro Sensor and Methods of Making - A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent. | 01-28-2010 |
20100018878 | METHOD OF REDUCING INTERFERENCES IN AN ELECTROCHEMICAL SENSOR USING TWO DIFFERENT APPLIED POTENTIALS - The present invention is directed to a method of reducing the effects of interfering compounds in the measurement of analytes and more particularly to a method of reducing the effects of interfering compounds in a system wherein the test strip utilizes two or more working electrodes. In one embodiment of the present invention, a first potential is applied to a first working electrode and a second potential, having the same polarity but a greater magnitude than the first potential, is applied to a second working electrode. | 01-28-2010 |
20100051481 | COULOMETRIC ANALYTE SENSING INSTRUMENT WITH AN ANALYTE-CONSUMING SENSOR IN A CLOSED CELL - A method for measuring the transmission rate of an analyte through a film. The method includes the steps of (i) separating a chamber into a first cell and a second cell with a known area of a film, (ii) flushing the first cell with an inert gas to remove any target analyte from the first cell, (iii) introducing a gas containing a known concentration of an analyte into the second cell, (iv) sealing the first cell to gas flow through the first cell, and (v) sensing any analyte in the first cell with a sensor that consumes the analyte at a rate greater than the rate at which the analyte is passing through the film, until a steady state rate of analyte consumption is measured by the sensor. | 03-04-2010 |
20100078335 | Method and apparatus for assay of electrochemical properties - A method for monitoring a select analyte in a sample in an electrochemical system. The method includes applying to the electrochemical system a time-varying potential superimposed on a DC potential to generate a signal; and discerning from the signal a contribution from the select analyte by resolving an estimation equation based on a Faradaic signal component and a nonfaradaic signal component. | 04-01-2010 |
20100140113 | GAS SENSOR CONTROL APPARATUS AND METHOD - There is provided a control apparatus for a gas sensor, which has a sensor element equipped with first and second oxygen pumping cells. The sensor control apparatus is configured to drive the first oxygen pumping cell to adjust the oxygen concentration of gas under measurement, drive the second oxygen pumping cell to produce a flow of electric current according to the amount of oxygen pumped out of the oxygen concentration adjusted gas by the second oxygen pumping cell, perform specific drive control to control the amount of oxygen pumped by the second oxygen pumping cell to a predetermined level after startup of the sensor element and before the application of the drive voltage between the electrodes of the second oxygen pumping cell. | 06-10-2010 |
20100147706 | SYSTEM AND METHOD FOR CODING INFORMATION ON A BIOSENSOR TEST STRIP - The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted. | 06-17-2010 |
20100193377 | Electrochemical Detection of Silica Species - A systems and apparatus for measuring non-electroactive materials in liquids using electrochemical detection. A first electrical activity of a electroactive material is detected in absence of a target non-electroactive material (Step | 08-05-2010 |
20100219085 | Analyte Sensor Offset Normalization - Measurements of current from a working electrode and current from a blank electrode are received and a ratio corresponding to the ratio of surface areas of the working electrode and the blank electrode is determined. This ratio is used to correct any differential current offset between an analyte (working) electrode and a control (blank) electrode to yield a more accurate net current output. Systems, methods and computer program products are further described for measuring an analyte concentration disclosed are for calculating the amount of an analyte in a fluid using a biosensor. | 09-02-2010 |
20100264041 | CONVERTER FOR USE WITH SENSING DEVICES - A system and method are disclosed for utilizing sensors with existing devices. An interface module is used in combination with a newer sensor, such as a fluorescence oxygen sensor, and an older legacy device. The older legacy device supplies a polarizing voltage, and anticipates a measured current of between 0 and 100 nA. The newer sensor requires no polarizing voltage and delivers an output of 0-10 volts in one embodiment, and 4-20 mA in another embodiment. The interface module receives the output from the sensor, and converts it into a useable signal to the legacy device. In another embodiment, the interface module comprises a number of outputs, such that both legacy devices and newer devices can be in communication with the sensor simultaneously. The interface module can be used in conjunction with a reactor chamber or other pharmaceutical process. | 10-21-2010 |
20100300897 | FLEXIBLE INDWELLING ELECTROCHEMICAL-BASED BIOSENSOR AND RELATED METHODS - A flexible indwelling electrochemical-based biosensor includes an elongated framework and an integrated electrochemical-based biosensor. The elongated framework is formed of an electrically conductive flexible material (e.g., a Nitinol) with a body portion, a sharp head, a distal end and a proximal end. The integrated electrochemical-based biosensor (such as an electrochemical-based glucose sensor) is integrated with the elongated framework in that the biosensor has a sensing element that is disposed over the body portion or sharp head of the elongated framework and a portion of the elongated framework is configured as an electrode component that electrically cooperates with the sensing element. The electrode component can, for example, be configured to electrically cooperate as a working electrode, counter electrode, reference electrode or combined reference/counter electrode of the sensing element. Moreover, the sharp head is disposed at the distal end of the elongated framework and the sharp head, the electrode component and at least the sensing element of the biosensor are configured for insertion into a target site (for example, a subcutaneous target site). | 12-02-2010 |
20110024307 | ANALYTE SENSOR - Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system | 02-03-2011 |
20110024308 | IMMUNOASSAY - Provided is an immunoassay for detecting a test substance with high sensitivity. The immunoassay is a method of detecting or measuring a test substance contained in a sample liquid, and includes: reacting, with the test substance, a first specifically binding substance which is immobilized on a support and is capable of binding specifically to the test substance and a second specifically binding substance which is labeled with a labeling substance and is capable of binding specifically to the test substance; separating, from the support, the second specifically binding substance which is unreactive with the test substance; eluting the labeling substance retained on the support; depositing the eluted labeling substance on a test element; and measuring electrochemically a catalyst reaction amount of the labeling substance deposited on the test element. | 02-03-2011 |
20110036729 | CONTROL LIQUID JUDGING METHOD AND ANALYSIS DEVICE - The present invention relates to a method for distinguishing between a sample and a control liquid in a system for analyzing a specific component in the sample by using an analyzing tool having a working electrode and an counter electrode. This discriminating method includes a first step of applying a voltage between the working electrode and the counter electrode, a second step of measuring a response current at certain intervals by use of the working electrode and the counter electrode, a third step of calculating a relative value for a peak value or an end value of the response current, a fourth step of calculating a change rate of the relative value, and a fifth step of distinguishing between the sample and the control liquid based on the change rate. | 02-17-2011 |
20110073495 | WATER ANALYSIS - A method of determining chemical oxygen demand (COD) of a water sample which is useful in a probe configuration includes the steps of a) applying a constant potential bias to a photoelectmchemical cell, having a photoactive working electrode optionally a reference electrode and a counter electrode, and containing a supporting electrolyte solution; b) illuminating the working electrode with a light source and recording the background photocurrent produced at the working electrode from the supporting electrolyte solution; c) adding a water sample, to be analysed, to the photoelectrochemical cell; d) illuminating the working electrode with a light source and recording the steady state photocurrent produced with the sample; e) determining the chemical oxygen demand of the water sample using the formula (I): where δ is the Nernst diffusion layer thickness, D is the diffusion coefficient, A is the electrode area, F the Faraday constant and iss the steady state photocurrent. The method can accommodate a broad range of light intensity and pH. | 03-31-2011 |
20110073496 | Error detection in analyte measurements based on measurement of system resistance - Measurement of the series track resistance of a working and counter electrode pair in an electrochemical test strip provide error detection for multiple variations in the quality of the test strip, as well as the operation of strip in the test meter. In particular, a single measurement of series resistance can be used to detect and generate an error message when an incorrect reading is likely to result due to (1) damaged electrode tracks, (2) fouled electrode surfaces, (3) dirty strip contacts, or (4) short circuit between the electrodes. | 03-31-2011 |
20110127172 | SYSTEMS AND METHODS FOR CARBOHYDRATE DETECTION - Carbohydrate detectors employing abiotic fuel cell designs are disclosed. The detectors produce current output using reactions between chemical dyes in alkaline solutions and carbohydrates, such as glucose. A linear relationship between current output of the detector and glucose concentration has been observed. This relationship may be used with measurements of current output when the glucose concentration is unknown to determine the unknown glucose concentration. In certain embodiments, the abiotic detectors may further employ electrodes, such as high surface area carbon materials and commercial air breathing electrodes, without the use of catalysts (i.e., precious metals or biocatalytic species) for glucose detection Organic dyes, such as methyl viologen (MV), methylene blue, methylene green, Meldola's blue, indigo carmine, safranin O, and the like, may serve as the electron mediators. | 06-02-2011 |
20110132774 | STRIP HAVING TEMPERATURE COMPENSATING FUNCTION AND METHOD OF MEASURING BLOOD GLUCOSE USING THE SAME - Disclosed is a strip having a temperature compensating function, in which the temperature of the strip for blood collection for use in a blood glucose monitor is sensed and used as an error compensation value upon measuring blood glucose, thereby obtaining a very accurate blood glucose measurement regardless of ambient temperature and humidity and which includes first and second electrodes formed adjacent to each other to measure blood glucose, a connector inserted into a blood glucose monitor so as to be electrically connected thereto and one surface of which has upper terminals respectively connected to the first and second electrodes, a rectangular substrate including a chemically reactive member applied on or attached to the first and second electrodes, an upper cover covering an upper surface of the substrate and including a cut part to expose portions of the first and second electrodes, and a temperature sensor attached to the substrate to sense the temperature of the strip. A method of measuring blood glucose using the strip is also provided. | 06-09-2011 |
20110155588 | METHOD FOR MEASURING ANALYTE CONCENTRATION IN A LIQUID SAMPLE - The blood glucose analysis technique and system described herein address the issue of hematocrit interference when rapidly detecting glucose concentrations. It addresses this issue by using a differential pulse voltammetry technique in which short high, frequency voltage pulses are applied to keep the diffusion layer within the reagent of the working electrode, and the pulses are applied in a limited voltage window (or range) that is below the peak, diffusion-limited current. The readings below the peak are then used to determine glucose concentrations. With this technique, glucose concentrations can be determined relatively fast (e.g., within 5 seconds) and independently of the hematocrit levels of the fluid being analyzed. | 06-30-2011 |
20110155589 | Systems, Devices, and Methods for Improving Accuracy of Biosensors Using Fill Time - Methods for determining a concentration of an analyte in a sample, and the devices and systems used in conjunction with the same, are provided herein. In one exemplary embodiment of a method for determining a concentration of an analyte in a sample, the method includes detecting a presence of a sample in an electrochemical sensor including two electrodes. A fill time of the sample is determined with the two electrodes and a correction factor is calculated in view of at least the fill time. The method also includes reacting an analyte that causes a physical transformation of the analyte between the two electrodes. A concentration of the analyte can then be determined in view of the correction factor with the same two electrodes. Systems and devices that take advantage of the fill time to make analyte concentration determinations are also provided. | 06-30-2011 |
20110168575 | SAMPLE CHARACTERIZATION BASED ON AC MEASUREMENT METHODS - One aspect concerns a technique for detecting analyte concentrations, such as glucose concentrations, in blood or other bodily fluids. This technique utilizes an electrochemical test strip that includes a mediator system that generates a linear faradic response at relatively low applied potential differences. An alternating current excitation signal is applied to blood in the test strip. The alternating current excitation signal includes a low frequency signal and a high frequency signal that has a higher frequency than the low frequency signal. The glucose concentration is determined by measuring a low frequency response to the low frequency signal, measuring a high frequency response to the high frequency signal, estimating the glucose concentration based on the low frequency response, and correcting the glucose concentration for one or more error-causing variables based on the high frequency response. | 07-14-2011 |
20110168576 | ELECTROCHEMICAL ASSAY - The invention provides an electrochemical assay for a phenol analyte in a body fluid sample wherein said sample, or fluid therefrom, is contacted with the working electrode of an electrode assembly comprising a working electrode, a counter-electrode, a voltage supply to said working and counter-electrodes and a current meter for determining the current between said working and counter-electrodes, and wherein a first compound capable of reversible oxidation and reduction is disposed at said working electrode, said first compound being capable in either an oxidized or a reduced form of binding to said phenol analyte, characterized in that said first compound in its oxidized or reduced form comprises a group of structure I R1-NH—C*—(C*—C*) | 07-14-2011 |
20110198240 | Sensors and Methods for Detecting Organic Carbonyl Species - A method for detecting an organic carbonyl species involves exposing a metal oxide-free film of a polyaniline to an environment suspected of containing an organic carbonyl species, detecting a change in electrical conductivity and/or an optical or luminescent property of the polyaniline, and, correlating the change in electrical conductivity and/or optical or luminescent property to a presence of the organic carbonyl species in the environment. Further, sensors for organic carbonyl species are disclosed having a metal oxide-free film of a polyaniline supported on an electrically insulating substrate. The method and sensors provide a good balance between response time and sensitivity, being considerably faster than metal oxide and metal oxide/polymer based sensors, while having greater sensitivity than other polymer-based sensors. | 08-18-2011 |
20110203942 | SENSOR CHIP, BIOSENSOR SYSTEM, METHOD FOR MEASURING TEMPERATURE OF BIOLOGICAL SAMPLE, METHOD FOR MEASURING TEMPERATURE OF BLOOD SAMPLE, AND METHOD FOR MEASURING CONCENTRATION OF ANALYTE IN BLOOD SAMPLE - A sensor chip ( | 08-25-2011 |
20110272294 | METHOD FOR MEASURING TEMPERATURE OF BIOLOGICAL SAMPLE, METHOD FOR MEASURING CONCENTRATION OF BIOLOGICAL SAMPLE, SENSOR CHIP AND BIOSENSOR SYSTEM - A sensor chip ( | 11-10-2011 |
20120031774 | ELECTRODE FOR AN ELECTROCHEMICAL DEVICE AND METHOD FOR DETECTING HYDROGEN PEROXIDE USING THE ELECTRODE - An electrode for an electrochemical device includes a conductor, and an active layer formed on the conductor and including a polybenzimidazole polymer that contains at least one of the functional group of the following formula: | 02-09-2012 |
20120031775 | PREPARATION OF MONOBASIC PHOSPHATE IONOPHORES - The present invention relates to the synthesis of lipophilic or immobilized monobasic phosphate (H | 02-09-2012 |
20120031776 | Transient Decay Amperometry - A biosensor system determines an analyte concentration of a biological sample using an electrochemical process without Cottrell decay. The biosensor system generates an output signal having a transient decay, where the output signal is not inversely proportional to the square root of the time. The transient decay is greater or less than the −0.5 decay constant of a Cottrell decay. The transient decay may result from a relatively short incubation period, relatively small sample reservoir volumes, relatively small distances between electrode surfaces and the lid of the sensor strip, and/or relatively short excitations in relation to the average initial thickness of the reagent layer. The biosensor system determines the analyte concentration from the output signal having a transient decay. | 02-09-2012 |
20120031777 | CONTROL AND CALIBRATION SOLUTIONS AND METHODS FOR THEIR USE - Control and calibration solutions are described that provide control and calibration data that is recognized by a test meter allowing the meter to segregate the control and calibration data from regular test data. Recognition and segregation of the control and calibration data can occur automatically with no additional input from the meter's user. Methods for use of the solutions are also provided. | 02-09-2012 |
20120067742 | LINKER, IMPEDANCE BIOCHIP, AND METHOD OF QUANTITATIVELY DETECTING TARGET ANALYTE IN FLUID SAMPLE USING THE BIOCHIP - The present invention provides a linker for joining an electrode and a capture probe on a biochip, and a biochip comprising the linker. The impedance baseline of the linker of the present invention is three orders lower than the conventional long chain thiol linker when adopting in a fadaraic impedance biochip construction. With lower impedance baseline, the device designed to measure the signal of the biochip of the present invention could be further simplied on the electrical circuit design and be made in lower cost, compacter size and get the potential to be used in point-of-care applications. The present invention also provides a method of quantitatively detecting a concentration of a target analyte in a fluid sample by adopting the biochip and the linker of present invention. | 03-22-2012 |
20120067743 | METHOD OF CORRECTING FOR OXYGEN EFFECT ON TEST SENSORS - An electrochemical test sensor is adapted to measure glucose and correct for the oxygen effect in a fluid sample. The test sensor comprises a base, first and second working electrodes, and a counter electrode. The first working electrode includes glucose oxidase, a mediator and peroxidase. The second working electrode includes glucose oxidase and the mediator. The first working electrode, the second working electrode and the counter electrode are located on the base. In other embodiments, an electrochemical test sensor is adapted to measure cholesterol, lactate, pyruvate or xanthine and correct for the oxygen effect in a fluid sample. | 03-22-2012 |
20120073987 | ELECTROCHEMICAL METHOD AND APPARATUS OF IDENTIFYING THE PRESENCE OF A TARGET - An electrochemical method of identifying the presence of a target protein in a sample is provided. The method comprises providing a redox probe modified to include a detector that is suitable to bind to the target protein, and exposing the sample to the detector-modified redox probe. A change in the electrochemical signal produced by the redox probe as compared to a control signal is indicative of the presence of the target protein. | 03-29-2012 |
20120080326 | SYSTEMS AND METHODS FOR IMPROVED STABILITY OF ELECTROCHEMICAL SENSORS - Methods for determining a concentration of an analyte in a sample, and the devices and systems used in conjunction with the same, are provided herein. In one exemplary embodiment of a method for determining a concentration of an analyte in a sample, a sample including an analyte is provided in a sample analyzing device having a working and a counter electrode. An electric potential is applied between the electrodes and a measurement of a parameter correlating to changes in a physical property of the sample analyzing device is calculated. A concentration of the analyte in view of the parameter correlating to a change in the physical property can then be determined Systems and devices that take advantage of the parameter correlating to changes in a physical property to make analyte concentration determinations are also provided. | 04-05-2012 |
20120080327 | METHOD FOR EVALUATING OXIDATION STRESS AND USE OF THE SAME - Provided is a simple, rapid blood cell analysis method (assay method using erythrocytes) utilizing a novel index. Using a measurement system having a working electrode and a counter electrode, an adhesion level of erythrocyte on the working electrode to which a positive potential, or a current that generates a positive potential, is applied is detected by an electrochemical measurement method. Oxidation stress is evaluated using the detection result. | 04-05-2012 |
20120097554 | ANALYTE SENSORS COMPRISING ELECTRODES HAVING SELECTED ELECTROCHEMICAL AND MECHANICAL PROPERTIES - Embodiments of the invention disclosed herein comprise amperometric glucose sensor systems that include multiple working electrodes having different material properties as well as algorithms and other elements designed for use with such systems. While embodiments of the innovation can be used in a number of contexts, typical embodiments of the invention include glucose sensors used to facilitate the management of diabetes. | 04-26-2012 |
20120103835 | SYSTEM AND/OR METHOD OF VALIDATING METERED BLOOD GLUCOSE FOR GLUCOSE SENSOR CALIBRATION - The subject matter disclosed herein relates to systems, methods and/or devices for calibrating sensor data to be used in estimating a blood glucose concentration. A relationship between sensor signal values and reference readings may be used to estimate a relationship between sensor signal values and measurements of blood glucose concentration. | 05-03-2012 |
20120132544 | ELECTROCHEMICAL SENSOR - An electrochemical sensor for measuring an analyte in a fluid, the electrochemical sensor having a first working electrode that includes a redox species sensitive to the analyte to be measured and a second working electrode made from a conducting substrate absent the redox species. The electrochemical sensor being capable of operation so that electrochemical effects of active contaminants in the fluid can be removed/attenuated from electrochemical signals produced by the reduction/oxidation of the redox species in the presence of the analyte. | 05-31-2012 |
20120160709 | PROCESSES AND SYSTEMS FOR CHARACTERIZING AND BLENDING REFINERY FEEDSTOCKS - Refinery feedstocks can be characterized based on any of: dissociation of acids in the crude, breakup of naphthenic acid molecular associations, and/or dissociation of sulfur compounds in the feedstocks. The characterization is performed as a function of temperature via any of electrical resistivity measurement, vibrational spectroscopic analysis, voltammetry, electrochemical impedance spectroscopy (EIS) and combinations thereof The method can be practiced in any of refinery, terminal, and laboratories. It can be used in conjunction with models and hardware to optimize the usage of refinery feedstocks in the blending and valuation of the feedstocks. In one embodiment, the characterization of refinery feedstocks is via the use of EIS. | 06-28-2012 |
20120181190 | Analyte Determination Methods and Devices - The present invention provides methods and apparatuses for analyte detection. | 07-19-2012 |
20120187000 | ELECTROCHEMICAL SENSORS - Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration. | 07-26-2012 |
20120205259 | Method and Apparatus for Assay of Electrochemical Properties - The presence of a select analyte such as glucose in the sample is evaluated in an electrochemical system using a conduction cell-type apparatus. A potential or current is generated between the two electrodes of the cell sufficient to bring about oxidation or reduction of the analyte or of a mediator in an analyte-detection redox system, thereby forming a chemical potential gradient of the analyte or mediator between the two electrodes after the gradient is established, the applied potential or current is discontinued and an analyte-independent signal is obtained from the relaxation of the chemical potential gradient. The analyte-independent signal is used to correct the analyte-dependent signal obtained during application of the potential or current. | 08-16-2012 |
20120205260 | SYSTEM AND METHOD FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A SAMPLE FLUID - The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 3.0 seconds or less, and/or having a clinically low Total System Error. | 08-16-2012 |
20120234699 | BIOSENSOR AND METHOD FOR DETERMINING AN ANALYTE CONCENTRATION - A method of determining an analyte concentration employs a biosensor that includes a molecularly imprinted polymer film formed on a metal layer. The biosensor is connected to a charge/discharge circuit and charged and discharged during exposure to a solution containing an analyte. Voltage values during discharge are measured, and a characteristic parameter of the voltage values, which is associated with a concentration of the analyte detected by the biosensor, is determined. An unknown concentration of the analyte is determined by comparing the characteristic parameter to reference data representing a relation between known concentration of the analyte and the characteristic parameter of the biosensor. A biosensor, such as an anesthetic biosensor, is also disclosed. | 09-20-2012 |
20120255875 | SYSTEMS AND METHODS FOR PROCESSING AND TRANSMITTING SENSOR DATA - Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate sensor information to one or more display devices. Establishment of communication between devices can involve using a unique identifier associated with the sensor electronics module to authenticate communication. Times tracked at the sensor electronics module and the display module can be at different resolutions, and the different resolutions can be translated to facilitate communication. In addition, the frequency of establishing communication channels between the sensor electronics module and the display devices can vary depending upon whether reference calibration information is being updated. | 10-11-2012 |
20120267259 | METHOD AND APPARATUS FOR DETECTING A LIPOPHILIC ANALYTE OF INTEREST IN A SAMPLE - Disclosed is a method and apparatus for detecting the concentration of a lipophilic analyte of interest in a complex sample matrix. The method comprises extracting the analyte of interest from said sample into an organic solvent comprising a dissolved electrolyte; providing a free radical species, preferably a free oxygen radical species, in said organic solvent; reacting the Canalyte of interest with said free radical species; and performing a measurement to detect the concentration of the free radical-reacted analyte reaction product. | 10-25-2012 |
20120298529 | OXIDATION/REDUCTION MEASUREMENT - Oxidation/reduction measurement is described. An aspect provides an oxidation/reduction quantification method, including: receiving intermittent oxidizer/reducer reference measurements from one or more reference sensors; receiving one or more substantially continuous oxidizer/reducer-related measurements from one or more corroboration sensors; and processing the one or more substantially continuous oxidizer/reducer-related measurements with the intermittent oxidizer/reducer reference measurements to generate substantially continuous representative oxidizer/reducer measurements. Other aspects are described. | 11-29-2012 |
20120305410 | Porous Particle Reagent Compositions, Devices, and Methods for Biosensors - A reagent composition for a biosensor sensor strip is disclosed that provides for rapid rehydration after drying. The composition includes porous particles and is preferably formed as a colloidal suspension. The dried reagent composition including porous particles may provide analytically useful output from the sensor strip in a shorter time period than observed from dried reagent compositions using solid particles. The output signal from the porous particle compositions may be correlated to the analyte concentration of a sample within about two seconds. In this manner, an accurate concentration determination of an analyte concentration in a sample may be obtained in less time than from sensor strips including conventional compositions. The reagent composition including the porous particles also may allow for the redox reaction between the reagents and the analyte to reach a maximum kinetic performance in a shorter time period than observed from conventional sensor strips. | 12-06-2012 |
20130001103 | SYSTEMS AND METHODS OF DISCRIMINATING CONTROL SOLUTION FROM A PHYSIOLOGICAL SAMPLE - Methods for distinguishing between an aqueous non-blood sample (e.g., a control solution) and a blood sample. In one aspect, the methods include using a test strip in which multiple current transients are measured by a meter electrically connected to an electrochemical test strip. The current transients are used to determine if a sample is a blood sample or an aqueous non-blood sample based on at least two characteristics (e.g., amount of interferent present and reaction kinetics). The method can also include calculating a discrimination criteria based upon at least two characteristics. Various aspects of a system for distinguishing between blood samples and an aqueous non-blood sample are also provided herein. | 01-03-2013 |
20130032493 | Sensor Arrangement for Continuously Monitoring Analytes in a Biological Fluid - A sensor for continuous detection of one or more analytes in a liquid flow, comprising an array of electrodes together forming an essentially planar sensing surface and a flow distributor with a flow inlet a flow channel and a flow outlet in order to establish a liquid flow of analytes along the sensing surface. The flow inlet and the flow outlet are located in a plane different to the plane of the sensing surface. The array of electrodes is arranged so that, in the direction from the flow inlet to the flow outlet, the array of electrodes consecutively comprises a first blank electrode, at least one measuring electrode, a second blank electrode, at least one measuring electrode and optionally a third blank electrode. | 02-07-2013 |
20130043141 | SYSTEM AND METHOD FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A SAMPLE FLUID - The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 3.0 seconds or less, and/or having a clinically low Total System Error. | 02-21-2013 |
20130043142 | METHOD AND APPARATUS FOR MEASURING OXIDATION-REDUCTION POTENTIAL - Methods and systems for measuring the oxidation-reduction potential of a fluid sample are provided. The system includes a test strip with a sample chamber adapted to receive a fluid sample. The sample chamber can be associated with a filter membrane. The test strip also includes a reference cell. The oxidation-reduction potential of a fluid sample placed in the sample chamber can be read by a readout device interconnected to a test lead that is in electrical contact with the sample chamber, and a reference lead that is in electrical contact with the reference cell. Electrical contact between a fluid sample placed in the sample chamber and the reference cell can be established by a bridge. The oxidation-reduction potential may be read as an electrical potential between the test lead and the reference lead of the test strip. | 02-21-2013 |
20130075278 | Preparation and Maintenance of Sensors - Apparatus and methods are described for preparing, maintaining, and stabilizing sensors. The apparatus and methods for preparing sensors for use are utilized in advance of the sensor being removed from a sealed, sterilized package. The apparatus include packaging materials having electrical circuits capable of stabilizing a sensor to prepare the sensor for use. The methods for preparing a sensor for use includes methods of providing a solution to a sterilized packaging that contains a sensor connected to a sensor activating circuit, activating the circuit, and allowing the sensor to stabilize. These methods can be performed without compromising the packaging. The apparatus for stabilizing a sensor that is in use include a circuit connectable to the sensor that provides a signal to the sensor that prevents the sensor from becoming destabilized when disconnected from a monitoring device. | 03-28-2013 |
20130118920 | SYSTEMS AND METHODS FOR IMPROVED ACCURACY FOR TEMPERATURE CORRECTION OF GLUCOSE RESULTS FOR CONTROL SOLUTION - Methods for determining a glucose concentration in a control solution with temperature correction that is more accurate than before with the devices and systems used in conjunction with the same, are provided herein. | 05-16-2013 |
20130175184 | Method and Apparatus for Encoding Test Strips - A test meter for receiving a test strip comprises:
| 07-11-2013 |
20130180868 | TEST METHOD FOR THE KETONE NUMBER OF AN ANIMAL SPECIMEN - A test method for the ketone number of an animal specimen is characterized in that a test parameter datasheet is set up by data modeling. Then a specimen from tested animal body is obtained. Next, the specimen is dripped onto the sensing end of an electrochemical test specimen, and an electrochemical tester is prepared. A test value correction procedure is built into or input to the electrochemical tester. With a parameter adjustment mode, the operational parameters of test value correction procedure unique to the electrochemical tester could be adjusted for adapting to the test mode of the species of tested animals. The sensing end of the electrochemical test specimen is inserted into the measurement slot of the electrochemical tester, so the ketone number of the specimen is displayed by the electrochemical tester. | 07-18-2013 |
20130220835 | POLYMERIC VDAT NANOPARTICLES FOR USE IN BIOSENSORS - A biosensor (such as an electrochemical-based analytical test strip configured for the determination of glucose in a whole blood sample) includes a substrate, an electrode disposed on the substrate and a uric acid scavenger layer containing polymeric vinyl-4,6-diamino-1,3,5-triazine (polyVDAT) nanoparticles. Aqueous compositions useful in, for example, the manufacturing of such biosensors include polyVDAT nanoparticles and water with the polyVDAT nanoparticles being present as a dispersion in the water. A method for determining an analyte in a bodily fluid sample containing uric acid includes applying a bodily fluid sample containing uric acid to a biosensor such that the bodily fluid sample comes into contact with a uric acid scavenger layer containing polymeric vinyl-4,6-diamino-1,3,5-triazine (polyVDAT) nanoparticles and determining the analyte based on an electronic signal produced by the biosensor. | 08-29-2013 |
20130220836 | SYSTEM AND METHOD FOR MEASURING AN ANALYTE IN A SAMPLE - Described are methods and systems to calculate an analyte concentration of a sample are provided without temperature compensation to a glucose concentration calculation when a measured or sampled current is taken at or before a change in a first voltage to a second voltage that are applied to a test trip with electrodes in a test cell. | 08-29-2013 |
20130220837 | SYSTEMS AND METHODS FOR CARBOHYDRATE DETECTION - Carbohydrate detectors employing abiotic fuel cell designs are disclosed. The detectors produce current output using reactions between chemical dyes in alkaline solutions and carbohydrates, such as glucose. A linear relationship between current output of the detector and glucose concentration has been observed. This relationship may be used with measurements of current output when the glucose concentration is unknown to determine the unknown glucose concentration. In certain embodiments, the abiotic detectors may further employ electrodes, such as high surface area carbon materials and commercial air breathing electrodes, without the use of catalysts (i.e., precious metals or biocatalytic species) for glucose detection Organic dyes, such as methyl viologen (MV), methylene blue, methylene green, Meldola's blue, indigo carmine, safranin O, and the like, may serve as the electron mediators. | 08-29-2013 |
20130220838 | SENSOR CHIP, AND MEASUREMENT DEVICE AND BLOOD TEST DEVICE IN WHICH THIS SENSOR CHIP IS USED - This sensor chip ( | 08-29-2013 |
20130228474 | CO-FACIAL ANALYTICAL TEST STRIP WITH STACKED UNIDIRECTIONAL CONTACT PADS - An analytical test strip (“ATT”) for use with a test meter includes a first insulating layer, with a first insulating layer upper surface, and a first electrically conductive layer (“ECL”) disposed thereon. The first ECL includes a first electrode portion (“EP”) and an electrical contact pad in electrical communication with the first EP. The ATT also includes a patterned spacer layer disposed above the first ECL that includes (i) a distal portion defining a bodily fluid sample-receiving chamber therein that overlies the first EP and (ii) an insulating proximal portion with an upper surface having a second ECL disposed thereon. The second ECL includes an interlayer contact portion and an electrical contact pad. A third ECL of the ATT includes a second EP and a proximal portion that overlies the interlayer contact portion. The second EP is disposed overlying and exposed to the sample-receiving chamber in an opposing relationship to the first EP. | 09-05-2013 |
20130228475 | CO-FACIAL ANALYTICAL TEST STRIP WITH STACKED UNIDIRECTIONAL CONTACT PADS AND INERT CARRIER SUBSTRATE - An analytical test strip with inert carrier substrate for use with a test meter includes an analytical test strip module and an electrochemically and electrically inert carrier substrate. The analytical test strip module has a first electrode portion, a second electrode portion in an opposing relationship to the first electrode portion, and first and second electrical contact pads configured in a stacked unidirectional configuration. The electrochemically and electrically inert carrier substrate has an upper surface and an outer edge. Moreover, the analytical test strip module is attached to the upper surface of the electrochemically and electrically inert carrier substrate such that the first and second electrical contact pads extend beyond the outer edge of the electrochemically and electrically inert carrier substrate and such that the electrochemically and electrically inert carrier substrate extends beyond the analytical test strip module. | 09-05-2013 |
20130256155 | ELECTRODE FOR BIOSENSOR FOR LPS DETECTION, A METHOD FOR PRODUCING IT AND A METHOD FOR REGENERATING IT - A method of forming a biosensor electrode for lipopolysaccharide (LPS) detection includes providing a metal electrode, forming a metal electrode/3-mercaptopropionic acid (MPA) by depositing MPA on the metal electrode, forming a metal electrode/MPA/n-hydroxy-succinimide (NHS) by ester-bonding NHS and the MPA on the metal electrode/MPA, forming a metal electrode/MPA/nitrilotriacetic acid (NTA) by amide-bonding NTA-C | 10-03-2013 |
20130256156 | Gated Amperometry Methods - A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Gated amperometric pulse sequences including multiple duty cycles of sequential excitations and relaxations may provide a shorter analysis time and/or improve the accuracy and/or precision of the analysis. The disclosed gated amperometric pulse sequences may reduce analysis errors arising from the hematocrit effect, variance in cap-gap volumes, non-steady-state conditions, mediator background, under-fill, temperature changes in the sample, and a single set of calibration constants. | 10-03-2013 |
20130264222 | MONITORING METHOD AND SYSTEM OF METAL IONS OR OXYGEN IONS APPLICABLE TO HIGH CONCENTRATION NON-AQUEOUS ELECTROLYTE - A monitoring method of metal ions or oxygen ions applicable to a high concentration non-aqueous electrolyte includes: applying a potential in a non-aqueous electrolyte to obtain current information with respect to the potential; varying the potential applied in the non-aqueous electrolyte containing metal ion concentration or oxygen ion concentration such that the metal ion concentration or the oxygen ion concentration is maintained in spite of the potential being applied; detecting a linear relationship among the concentration, the current, and passed charges in the non-aqueous electrolyte by repeatedly performing the obtaining step and the varying step, while changing the concentration; and calculating metal ion concentration or oxygen ion concentration of the non-aqueous electrolyte in pyroprocessing of the non-aqueous electrolyte by using the linear relationship. Concentration and components of a solute existing in a non-aqueous electrolyte can be measured while an electrowinning process and pyroprocessing is being conducted. | 10-10-2013 |
20130277235 | CONTROLLED SLEW RATE TRANSITION FOR ELECTROCHEMICAL ANALYSIS - Measurement systems and methods are disclosed for minimizing the effects created by a meter's output amplifier during electrochemical measurements. In the systems and methods, transition of an excitation potential applied between electrodes of a test strip is controlled so that it is at a sufficiently slow rate below a slew rate capability of the system (but still fast enough to minimally impact overall test time) to reduce variability in the test results. The methods and systems therefore use a transition having a ramp-shaped waveform, a sinusoidal-shaped waveform or an exponential-shaped waveform. Additionally, the excitation potential can be purposefully controlled by a processor, memory driven digital-to-analog converter or external circuitry at a rate sufficiently slow to make variations in the analog electronics slew rate insignificant for all sample types and test conditions. | 10-24-2013 |
20130284611 | ANALYTE MEASUREMENT TECHNIQUE AND SYSTEM - Described are methods and systems to apply a plurality of test voltages to the test strip and measure a current transient output resulting from an electrochemical reaction in a test chamber of the test strip so that highly accurate glucose concentration can be determined. | 10-31-2013 |
20130306493 | SYSTEMS AND METHODS FOR HIGH ACCURACY ANALYTE MEASUREMENT - Methods for determining a concentration of an analyte in a sample, and the devices and systems used in conjunction with the same, are provided herein. In one exemplary embodiment of a method for determining a concentration of an analyte in a sample, a sample including an analyte is provided in a sample analyzing device having a working and a counter electrode. An electric potential is applied between the electrodes and a first analyte concentration is determined. A second analyte concentration value is calculated from the first analyte concentration value and corrected for temperature effects, fill time and capacitance to provide for a final analyte concentration value. | 11-21-2013 |
20130334064 | CALIBRATION METHOD, TEST STRIP AND CALIBRATION SYSTEM FOR BLOOD GLUCOSE OF BLOOD SAMPLE - A calibration method for blood glucose of blood sample comprises the following steps: applying a first voltage to a blood sample to obtain an original level of blood glucose of the blood sample; applying a second voltage to a blood sample to obtain a hematocrit index of the blood sample; and processing the hematocrit index and calibrating the original level of blood glucose of the blood sample. The absolute value of the first voltage is lower than 1 volt and is not equal to 0 volt. The absolute value of the second voltage is higher than or equal to 1 volt. A sensing current corresponding to the original blood level and the hematocrit index corresponding to blood sample are obtained by applying at least two-stage voltages in the specific range to the blood sample, thereby calibrating the original blood glucose according to the hematocrit index. | 12-19-2013 |
20130341207 | ANALYTICAL TEST STRIP WITH CAPILLARY SAMPLE-RECEIVING CHAMBERS SEPARATED BY STOP JUNCTIONS - An analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (e.g., a whole blood sample) includes a first and second capillary sample-receiving chambers and first and second stop junctions that are disposed between the first and second capillary sample-receiving chambers. The first stop junction defines a discontinuity boundary of the first capillary sample-receiving chamber and the second stop junction defines a discontinuity boundary of the second capillary sample-receiving chamber. In addition, the first stop junction and the second stop junction are disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber during use of the analytical test strip is prevented. | 12-26-2013 |
20130341208 | ELECTROCHEMICAL-BASED ANALYTICAL TEST STRIP WITH INTERSECTING SAMPLE-RECEIVING CHAMBERS - An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) and/or a characteristic of the bodily fluid sample (for example, hematocrit) includes a first sample-receiving chamber with first and second sample-application openings, and first and second electrodes. The first and second electrodes are disposed in the first sample-receiving chamber between the first and second sample-application openings. The electrochemical-based analytical test strip also includes a second sample-receiving chamber and a plurality of electrodes disposed in the second sample-receiving chamber. In addition, the second sample-receiving chamber intersects the first sample-receiving chamber between the first and second electrodes, thereby defining a chamber intersection. | 12-26-2013 |
20130341209 | ANALYTICAL TEST STRIP WITH CAPILLARY SAMPLE-RECEIVING CHAMBERS SEPARATED BY A PHYSICAL BARRIER ISLAND - An analytical test strip for the determination of an analyte (such as glucose and/or hematocrit) in a bodily fluid sample (such as a whole blood sample) includes a first capillary sample-receiving chamber, a second capillary sample-receiving chamber, and a physical barrier island disposed between the first and second capillary sample-receiving chambers. Moreover, the physical island barrier is disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber is prevented during use of the analytical test strip. | 12-26-2013 |
20140083867 | METHOD AND SYSTEM TO DERIVE MULTIPLE GLYCEMIC PATTERNS FROM GLUCOSE MEASUREMENTS DURING TIME OF THE DAY - Described are methods and systems for determining modal patterns from an overall trend, minor trend or significant trend for various periods during a time of the day modal report which can be utilized to provide insights to the person with diabetes. | 03-27-2014 |
20140083868 | SYSTEM AND METHOD FOR MEASURING AN ANALYTE IN A SAMPLE AND CALCULATING GLUCOSE RESULTS TO ACCOUNT FOR PHYSICAL CHARACTERISTICS OF THE SAMPLE - Described are methods and systems to apply a plurality of test voltages to the test strip and measure a current transient output resulting from an electrochemical reaction in a test chamber of the test strip so that a glucose concentration can be determined that account for hematocrits in both typical subjects and neonates. | 03-27-2014 |
20140083869 | Detection Of Endotoxins - A complex comprises a polyene macrolide antibiotic and an endotoxin. Methods and devices detect the complex. A polymeric material functionalized with a polyene macrolide antibiotic is employed in the devices. | 03-27-2014 |
20140083870 | Method for Determination of Analyte Concentrations and Related Apparatus - A method is provided for determining analyte concentrations, for example glucose concentrations, that utilizes a dynamic determination of the appropriate time for making a glucose measurement, for example when a current versus time curve substantially conforms to a Cottrell decay, or when the current is established in a plateau region. Dynamic determination of the time to take the measurement allows each strip to operate in the shortest appropriate time frame, thereby avoiding using an average measurement time that may be longer than necessary for some strips and too short for others. | 03-27-2014 |
20140090989 | SYSTEM AND METHOD FOR DETERMINING HEMATOCRIT INSENSITIVE GLUCOSE CONCENTRATION - Described are methods and systems to apply a plurality of test voltages to the test strip and measure at least a current transient output resulting from an electrochemical reaction in a test chamber of the test strip so that a glucose concentration can be determined that are generally insensitive to other substances in the body fluid sample that could affect the precision and accuracy of the glucose concentration. | 04-03-2014 |
20140116893 | SYSTEM AND METHOD FOR REDUCTION OF PERCEIVED INACCURACY OF ANALYTE MEASUREMENTS - Described are methods and systems to reduce or obviate complaints about “inaccuracy” of blood glucose meter which utilize an exemplary technique to distinguish between subjective and objective inaccuracies of the analyte measurements. | 05-01-2014 |
20140116894 | Method and apparatus for monitoring alteration of flow characteristics in a liquid sample - A device for measuring blood coagulation time is formed from a first substrate; a second substrate; a spacer layer disposed between the first and second substrates, said spacer layer having an opening formed therein defining a sample receiving chamber, a vented sink chamber, and an elongated reservoir forming a conduit for liquid movement between the sample receiving chamber and the sink chamber; a first electrode disposed on the first substrate, said first electrode being exposed in the reservoir portion through a first opening in the spacer layer; and a second electrode disposed on the second substrate, said second electrode being exposed in the reservoir portion through a second opening in the spacer layer. The device of the invention is used in combination with an apparatus that is connected to the first and second electrodes for measuring current flow between the first and second electrodes. Changes in observed current are indicative of flow through the device, and a cessation of flow indicates coagulation. | 05-01-2014 |
20140124384 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS - Systems and methods for multiple analyte analysis are provided. In one embodiment, a method includes determining concentrations of first and second analytes in a sample. The first and second analytes may be, for example, glucose and hydroxybutyrate. In this form, an indication related to the measured concentration of hydroxybutyrate is provided in response to determining that the concentration of hydroxybutyrate is above a predetermined value. In a further aspect of this form, a quantitative indication representative of the measured glucose concentration is automatically provided regardless of the value of the measured glucose concentration. In another embodiment, a system includes a meter configured to interact with a test element to assess first and second analytes in a sample. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings. | 05-08-2014 |
20140138261 | SYSTEM AND METHOD FOR DETERMINATION OF A CONCENTRATION OF AT LEAST ONE INTERFERING SUBSTANCE AND CORRECTION OF GLUCOSE CONCENTRATION BASED ON THE CONCENTRATION OF THE INTERFERING SUBSTANCE - Described are methods and systems to apply a plurality of test voltages to the test strip and measure a current transient output resulting from an electrochemical reaction in a test chamber of the test strip so that an estimated interferent value can be determined so that such interferent value can be used to correct the current transients at specific time points for more accurate glucose concentration determination. | 05-22-2014 |
20140151243 | SYSTEMS AND METHODS OF DISCRIMINATING BETWEEN A CONTROL SAMPLE AND A TEST FLUID USING CAPACITANCE - Methods for distinguishing between an aqueous non-blood sample (e.g., a control solution) and a blood sample are provided herein. In one aspect, the method includes using a test strip in which multiple current transients are measured by a meter electrically connected to an electrochemical test strip. The current transients are used to determine if a sample is a blood sample or an aqueous non-blood sample based on characteristics of the sample (e.g., amount of interferent present, reaction kinetics, and/or capacitance). The method can also include calculating a discrimination criteria based upon these characteristics. Various aspects of a system for distinguishing between a blood sample and an aqueous non-blood sample are also provided herein. | 06-05-2014 |
20140151244 | SYSTEMS AND METHODS OF DISCRIMINATING BETWEEN A CONTROL SAMPLE AND A TEST FLUID USING CAPACITANCE - Methods for distinguishing between an aqueous non-blood sample (e.g., a control solution) and a blood sample are provided herein. In one aspect, the method includes using a test strip in which multiple current transients are measured by a meter electrically connected to an electrochemical test strip. The current transients are used to determine if a sample is a blood sample or an aqueous non-blood sample based on characteristics of the sample (e.g., amount of interferent present, reaction kinetics, and/or capacitance). The method can also include calculating a discrimination criteria based upon these characteristics. Various aspects of a system for distinguishing between a blood sample and an aqueous non-blood sample are also provided herein. | 06-05-2014 |
20140151245 | SYSTEMS AND METHODS OF DISCRIMINATING BETWEEN A CONTROL SAMPLE AND A TEST FLUID USING CAPACITANCE - Methods for distinguishing between an aqueous non-blood sample (e.g., a control solution) and a blood sample are provided herein. In one aspect, the method includes using a test strip in which multiple current transients are measured by a meter electrically connected to an electrochemical test strip. The current transients are used to determine if a sample is a blood sample or an aqueous non-blood sample based on characteristics of the sample (e.g., amount of interferent present, reaction kinetics, and/or capacitance). The method can also include calculating a discrimination criteria based upon these characteristics. Various aspects of a system for distinguishing between a blood sample and an aqueous non-blood sample are also provided herein. | 06-05-2014 |
20140151246 | Gated Voltammetry Methods - A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Gated voltammetric pulse sequences including multiple duty cycles of sequential excitations and relaxations may provide a shorter analysis time and/or improve the accuracy and/or precision of the analysis. The disclosed pulse sequences may reduce analysis errors arising from the hematocrit effect, variance in cap-gap volumes, non-steady-state conditions, mediator background, a single set of calibration constants, under-fill, and changes in the active ionizing agent content of the sensor strip. | 06-05-2014 |
20140166503 | METHOD AND DEVICE FOR MEASURING HEMATOCRIT - An approach is provided for a method and device for measuring Hematocrit (Hct) are disclosed that measures current variations from reactions of Electrochemistry on the electrodes. The method comprises acts of giving a blood sample on a pair of electrodes, obtaining a response current by providing a voltage on the electrodes, and determining an Hct value from the obtained current based on a predetermined rule. Therefore, the present disclosure provides higher reliable and precise measurement compared to the conventional measuring apparatus. | 06-19-2014 |
20140174953 | HAND-HELD TEST METER CONFIGURED FOR DISTINGUISHING ORIENTATION OF ANALYTICAL TEST STRIP INSERTION - A hand-held test meter for use with an analytical test strip (such as an electrochemical-based analytical test strip) in the determination of an analyte (e.g., glucose) in a bodily fluid sample (such as a whole blood sample) includes a housing, a display block, a micro-controller disposed in the housing, a strip detection circuit block disposed in the housing, and a strip port connector with a test strip insertion detector(s). The test strip insertion detector(s) and strip detection circuit block are configured to detect the insertion of an analytical test strip into the strip port connector and send an insertion signal to the micro-controller upon such detection. In addition, the micro-controller is configured to receive the insertion signal, distinguish an orientation of analytical test strip insertion based on at least the insertion signal and signal the display module to display a predetermined message to a user based on the distinguished orientation of analytical test strip insertion. | 06-26-2014 |
20140197045 | SIMULTANEOUSLY QUANTIFYING AN ALKANE AND OXYGEN USING A SINGLE SENSOR - An alkane gas is supplied to an interface between an activated surface of a platinum or palladium working electrode and an ionic liquid electrolyte. The alkane adsorbs at or near an interface complex formed at the interface. The ionic liquid electrolyte is selected from a group consisting of 1-ethyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, 1-propyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, 1 -pentyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, 1-hexyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, 1 -heptyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, 1 -octyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, 1 -nonyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide, and 1-decyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imidem, and combinations thereof. While the alkane gas in the presence of oxygen is supplied to the interface, positive electrode potential is applied to the platinum or palladium working electrode, which causes oxidation of the adsorbed alkane to form a reaction product. A concentration of the alkane is quantified using an alkane anodic current or current density at the positive electrode potential. The alkane is used as an internal standard to calibrate oxygen detection. | 07-17-2014 |
20140202882 | PEAK OFFSET CORRECTION FOR ANALYTE TEST STRIP - Measurement with a test strip having two working electrodes ( | 07-24-2014 |
20140209484 | VALPROIC ACID BIOSENSOR AND METHOD FOR MEASURING CONCENTRATION OF VALPROIC ACID - The present disclosure relates to a valproic acid biosensor. In some embodiments, the valproic acid biosensor may comprise a microcantilever, a self-assembly monolayer, and a valproic acid antibody layer. The self-assembly monolayer may immobilize on the microcantilever surface. The valproic acid antibody layer may immobilize on the self-assembly monolayer. The valproic acid antibody layer may be used to bind with valproic acid drug samples. The present disclosure further relates to methods for measuring the concentration of valproic acid drug samples. | 07-31-2014 |
20140216951 | Modular Analyte Measurement System with Extendable Strip Port - A modular analyte measurement system having a removable strip port module. In one embodiment, the analyte measurement system includes: an analyte meter; a removable strip port module; and a connector linking the removable strip port module to the analyte meter. The analyte meter includes: a meter housing; a receptacle formed in the meter housing; a processing circuit disposed within the housing; and an input interface within the receptacle and electrically coupled to the processing circuit. The removable strip port module includes: a module housing sized to at least partially fit within the receptacle of the analyte meter; an analyte test strip port disposed within the module housing to receive an analyte test strip via an aperture formed in the module housing; and an output interface coupled to the analyte test strip port. The connector links the output interface with the input interface. | 08-07-2014 |
20140231272 | SULPHITE SENSOR AND METHOD FOR MEASURING SULPHITE CONCENTRATION IN A SUBSTANCE - The present invention relates to a method for measuring a concentration of sulphite in a substance in a gas cleaning process, the method comprising the steps of sending a plurality of voltage pulses through the substance by a first electrode ( | 08-21-2014 |
20140238874 | AMBIENT LIGHT COMPENSATION CIRCUIT FOR ANALYTE MEASUREMENT SYSTEMS - A blood analyte measurement system is configured to receive a test strip. An LED proximate to the test strip is used to illuminate the test strip and, in conjunction with a photodiode, to determine its type. A compensation circuit of the measurement system insures that ambient light does not cause interference with the LED illumination to prevent saturation of the photodiode. | 08-28-2014 |
20140251833 | METHODS AND SYSTEMS TO DETERMINE FILL DIRECTION AND FILL ERROR IN ANALYTE MEASUREMENTS - Various embodiments for methods and systems that allow for detecting of a direction in which a sample is flowing towards a plurality of electrodes and detecting a fill error of an electrochemical test strip. | 09-11-2014 |
20140262833 | SENSOR WITH A BIFURCATED FLOWPATH - A sensor having a bifurcated flow path and method for using the same is disclosed. In some embodiments, the sensor has two flow channels into which sample flow is induced by capillary action, wherein the flow channels are in contact with electrodes configured to generate an electrochemical reaction in the flow channels which can be measured and correlated to the level of an analyte in the sample. In some embodiments, the levels of more than one analyte can be measured using a single sensor. | 09-18-2014 |
20140284223 | Accurate Analyte Measurements for Electrochemical Test Strip Based on Sensed Physical Characteristic(s) of the Sample Containing the Analyte and Derived BioSensor Parameters - Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic, typically hematocrit, of the sample containing the analyte and deriving from this characteristic a parameter relating to the biosensor to attain accurate glucose concentration. | 09-25-2014 |
20140291169 | Measurement and Uses of Oxidative Status - The present invention provides a method of determining the overall oxidative status of a body fluid or a tissue of a patient by measuring the oxidation-reduction potential (ORP) of the body fluid or tissue. The method has been found to be useful in the diagnosis, evaluation and monitoring of patients who have suffered a trauma (such as a head injury), patients suspected of being critically-ill or who are critically ill, patients who have an infection, and patients suspected of having a myocardial infarction (MI) or who have had an MI. The method has also been found useful in monitoring and evaluating exercise performance in patients. In addition, the method has been found useful in monitoring and evaluating stored blood products and patients who will receive such a product. | 10-02-2014 |
20140299483 | ANALYTE METER AND METHOD OF OPERATION - An analyte meter having a test strip port is configured to transmit an electric signal through a received test strip with a sample. A pair of electrodes apply the electric signal and receive an electrical response from the test strip. A processing unit analyzes the electrical response and uses the response to determine an analyte level of the sample. | 10-09-2014 |
20140299484 | Medical Kit With Visually Enhanced Outer Layer For Accommodating Equipment With Visually Enhanced Removable Protective Coverings - A resilient sleeve removably encases a body fluid monitor. The sleeve and a corresponding medical kit include a visually enhancing adornment for promoting the optical recognizability of the encased body fluid monitor and the kit. This is useful in medical emergencies when locating the body fluid monitor can be the difference between life and death. The visually enhancing adornment can include a highly visible color and/or indicia such as a letter, word, phrase and/or logo. In some embodiments the highly visible color is contrastable to blood and/or orange. In some embodiments the color of the inside of the kit is in contrast to the color of the resilient sleeve. | 10-09-2014 |
20140299485 | DEVICE AND METHOD FOR DETECTING REDOX REACTIONS IN SOLUTIONS - Described herein is a device comprising a plurality of first reaction electrodes arranged in an array, the plurality of first reaction electrodes configured to be exposed to a solution and having a capacitance; first circuitry configured to controllably connect the plurality of first reaction electrodes to a bias source and controllably disconnect the plurality of first reaction electrodes from the bias source; and second circuitry configured to measure a rate of charging or discharging of the capacitance. Also described herein is a method of using this device to sequence DNA. | 10-09-2014 |
20140305811 | METHODS FOR THE ELECTROCHEMICAL TREATMENT OF SELF-ASSEMBLED MONOLAYERS - The present invention provides compositions and methods directed to an electrode initialization step for the electrochemical treatment of monolayers used in electrochemical detection of target analytes on the surface of a monolayer. Electrode initialization creates a more stable monolayer, and resolves variability within the electrochemical signal detected on the monolayer. | 10-16-2014 |
20140318986 | ANALYTE METER DIGITAL SAMPLE DETECTION - An analyte meter is configured to digitally test for the presence of a test strip in the meter and for the presence of a sample in the test strip prior to activating an analog current measurement circuit of the meter. A test strip port connector having a plurality of contacts receives an inserted test strip in which the contacts electrically connect to electrodes on the test strip for digitally detecting both the presence of a test strip and a sample added to the test strip. A control circuit monitoring the contacts maintains the analyte meter in a low power mode until detecting both the test strip and the sample, whereupon the control circuit activates the meter and enables an analog analyte measurement circuit. | 10-30-2014 |
20140318987 | ANALYTE METER TEST STRIP DETECTION - An analyte meter having a test strip port is configured to detect whether an approved test strip has been inserted into the test strip port before turning on analyte measurement subsystems in the analyte meter. After the meter is turned on, control circuitry in the meter continues to monitor whether the test strip is removed prior to application of a blood sample on the test strip or whether the test strip is removed after application of a blood sample on the test strip, such as during an assay of the sample. | 10-30-2014 |
20140318988 | ELECTROCHEMICAL SENSOR AND METHOD FOR MANUFACTURING - The present disclosure relates to a sensor including an elongated member including at least a portion that is electrically conductive. The elongated member includes a sensing layer adapted to react with a material desired to be sensed. An insulating layer surrounds the elongated member. The insulating layer defines at least one access opening for allowing the material desired to be sensed to enter an interior region defined between the elongated member and the insulating layer. The insulating layer has an inner transverse cross-sectional profile that is different from an outer transverse cross-sectional profile of the elongated member. The difference in transverse cross-sectional profiles between the elongated member and the insulating layer provides channels at the interior region defined between the insulating layer and the elongated member. The channels extend generally along the length of the elongated member and are sized to allow the material desired to be sensed to move along the length of the sensor. | 10-30-2014 |
20140332410 | ANALYTICAL MICRO-DEVICES FOR MENTAL HEALTH TREATMENT MONITORING - A lab on a chip device includes a whole blood inlet port and microchannels to transport a whole blood sample or plasma skimmed from the whole blood sample into a detection chamber that includes at least one 3-electrode set of a counter electrode, a working electrode and a reference electrode. The counter electrode, the working electrode and the reference electrode may present bare, unmodified surfaces that are disposed so that clozapine present in the whole blood sample is detected via a reduction-oxidation reaction. Alternatively, the working electrode surface may include catechol grafted to chitosan. A method of detecting analytes and biomarkers includes collecting a whole blood sample, loading the sample into a point-of-care testing (POCT) device that includes at least one working electrode; testing the sample for the occurrence of a redox reaction; and calculating the total oxidative charge when the working electrode is bare or modified as before. | 11-13-2014 |
20140374277 | Universal Test Strip Port - The present disclosure provides a sensor port configured to receive a plurality of analyte sensors having different sizes, shapes and/or electrode configurations. Also provided are analyte meters, analyte monitoring devices and/or systems and drug delivery devices and/or systems utilizing the disclosed sensor ports. | 12-25-2014 |
20150021205 | Sampling method and system for measuring blood lactate concentrations - A method of measuring lactate in a blood sample taken from capillary blood using a skin lancing procedure includes disposing onto an area of skin on an animal a predefined amount of a skin treatment compound that is capable of suppressing and/or eliminating and/or preventing and/or blocking any sweat from the skin in the area of a lanced wound site, the compound being disposed on the skin either before lancing the area of skin that provides a droplet of capillary blood for measurement of blood lactate concentration or after lancing the area of skin but before a droplet of capillary blood forms on the skin in order to prevent contaminating the blood sample, and then measuring the lactate concentration of the blood sample with a disposable lactate sensor strip. | 01-22-2015 |
20150060301 | Multiple-Biosensor Article - An article suitable for conducting one or more assays with an apparatus, e.g., a meter, for determining the presence or concentration of an analyte in a sample of biological fluid. The article contains a plurality of biosensors arranged in such a manner that each of the biosensors can be utilized before the article must be removed from the apparatus. | 03-05-2015 |
20150068923 | BIOSENSOR MONITORS, TEST STRIPS AND ACTIVATION MECHANISMS AND METHODS THEREOF - The disclosure is directed to biosensor monitors, test strips and activation mechanisms and methods thereof. The biosensor monitor is for verifying a test strip to be used with the biosensor monitor. The monitor includes verification components located within the monitor and accessible to a test strip to be inserted into the biosensor monitor. The verification components interact with verification portions of the test strip to allow the biosensor monitor to verify the test strip before the biosensor monitor tests biological material on the test strip. A test strip and methods are also described. | 03-12-2015 |
20150068924 | BLOOD GLUCOSE MEASUREMENT MODULE, SMART PHONE COMBINABLE WITH THE BLOOD GLUCOSE MEASUREMENT MODULE, AND BLOOD GLUCOSE MEASUREMENT METHOD USING THE SAME - Disclosed herein are a blood glucose measurement module, a smart phone combinable with the blood glucose measurement module, and a blood glucose measurement method using the same. The blood glucose measurement module includes a body, a strip reception slit, and a plug. The body includes a blood glucose measurement unit for measuring a blood glucose level of blood absorbed into a test strip and a CPU for calculating and transmitting the results of the measurement of the blood glucose level. The strip reception slit is formed in a part of the body, and receives the test strip. The plug is formed on one end surface of the body, and is easily fitted into the socket of a smart phone. | 03-12-2015 |
20150076004 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS - Systems and methods for multiple analyte analysis are provided. In one embodiment, a method includes determining concentrations of first and second analytes in a sample. The first and second analytes may be, for example, glucose and hydroxybutyrate. In this form, an indication related to the measured concentration of hydroxybutyrate is provided in response to determining that the concentration of hydroxybutyrate is above a predetermined value. In a further aspect of this form, a quantitative indication representative of the measured glucose concentration is automatically provided regardless of the value of the measured glucose concentration. In another embodiment, a system includes a meter configured to interact with a test element to assess first and second analytes in a sample. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings. | 03-19-2015 |
20150083613 | Electrochemical Biosensor with Improved Accuracy - The present invention relates to an electrochemical biosensor with improved hematocrit measurement accuracy for measuring blood glucose. According to the present invention, an electrochemical biosensor including a first electrode part for correcting a measured hematocrit value and a second electrode part for measuring a glucose concentration is effective in improving accuracy of a measured hematocrit value and in more improving accuracy of a measured blood glucose concentration using the measured hematocrit values for correction, because an insulation cover is made thinner than a working electrode and an auxiliary electrode, so that areas of a first working electrode and a first auxiliary electrode of the first electrode part exposed to a blood sample become equal; a distance between the first working electrode and the second working electrode becomes constant; and electrode areas are maintained constantly by the insulation cover even when a positioning error occurs during printing. | 03-26-2015 |
20150096904 | METHOD FOR MEASURING TEMPERATURE OF BIOLOGICAL SAMPLE, MEASURING DEVICE, AND BIOSENSOR SYSTEM - The concentration measurement method includes: introducing a predetermined amount of the biological sample into the capillary; measuring a temperature of the biological sample by applying a first voltage to the electrode unit when the temperature of the biological sample is measured, the first voltage allowing the temperature measurement to be less affected by increase and reduction in an amount of the analyte contained in the biological sample; measuring the concentration of the analyte contained in the biological sample by applying a second voltage to the electrode unit; measuring an environmental temperature in a surrounding of the biological sample; and correcting the concentration of the measured analyte based on the measured temperature of the biological sample and the measured environmental temperature. | 04-09-2015 |
20150144506 | SYSTEM, METHOD AND DEVICE FOR ANALYSIS OF CARBOHYDRATES - Embodiments of the present disclosure are directed to recognition tunneling methods, systems and devices for the detection of carbohydrates by measuring tunneling currents of sugars which give distinct electronic signals in a tunnel gap functionalized respectively with, for example, in some embodiments, 4(5)-(2-mercaptoethyl)-1H imideazole-2-carboxamide and 4-mercaptophenylboronic acid molecules on at least one, and preferably each electrode. | 05-28-2015 |
20150300969 | NONLINEAR MAPPING TECHNIQUE FOR A PHYSIOLOGICAL CHARACTERISTIC SENSOR - A method of measuring blood glucose of a patient is presented here. In accordance with certain embodiments, the method applies a constant voltage potential to a glucose sensor and obtains a constant potential sensor current from the glucose sensor, wherein the constant potential sensor current is generated in response to applying the constant voltage potential to the glucose sensor. The method continues by performing an electrochemical impedance spectroscopy (EIS) procedure for the glucose sensor to obtain EIS output measurements. The method also performs a nonlinear mapping operation on the constant potential sensor current and the EIS output measurements to generate a blood glucose value. | 10-22-2015 |
20150369769 | END-FILL ELECTROCHEMICAL-BASED ANALYTICAL TEST STRIP WITH PERPENDICULAR INTERSECTING SAMPLE-RECEIVING CHAMBERS - An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) and/or a characteristic of the bodily fluid sample (e.g., hematocrit) includes a sample-entry chamber with a sample-application opening disposed on an end edge of the electrochemical-based analytical test strip, and first and second sample-determination chambers, each in direct fluidic communication with the sample-entry chamber. The electrochemical-based analytical test strip also includes first and second electrodes (such as first and second hematocrit electrodes) disposed in the first sample-determination chamber, and a third and fourth electrodes (for example working and reference electrodes) disposed in the second sample-determination chamber. Moreover, the first and second sample-determination chambers intersect the sample-entry chamber perpendicular (or nearly perpendicular) to one another and the first sample-determination chamber also intersects the sample-entry chamber in an aligned manner. | 12-24-2015 |
20150369775 | ELECTROANALITICAL SYSTEM - An electroanalytical system useful for measuring analytes, such as sugar, sulfites, and ethanol in wine, includes a printed copper electrode in an alkaline medium, a flow injection system to contact very small samples with the copper electrode, current measurement to measure current flowing in a cell containing the copper electrode and a data processor connected to the copper electrode. The copper electrode has a copper oxide surface. Results are obtained by comparing known current flows for particular analytes with the flows obtained for the sample. | 12-24-2015 |
20150377825 | CALIBRATION METHOD FOR BLOOD GLUCOSE OF BLOOD SAMPLE - A calibration method for blood glucose of a blood sample includes steps of: applying a first voltage to a blood sample to obtain a first blood glucose level; applying a second voltage to the blood sample to obtain a second blood glucose level; applying a third voltage to the blood sample to obtain a hematocrit index of the blood sample; and processing the hematocrit index and calibrating the second blood glucose level. The third voltage is higher than the first voltage. Through this disclosure, user can obtain a sensing current corresponding to the blood glucose level and a hematocrit index corresponding to blood sample by applying at least three-stage voltages within specific ranges to the blood sample, and further calibrate the blood glucose concentration according to the hematocrit index. | 12-31-2015 |
20160003765 | METHODS OF USING INFORMATION FROM RECOVERY PULSES IN ELECTROCHEMICAL ANALYTE MEASUREMENTS AS WELL AS DEVICES, APPARATUSES AND SYSTEMS INCORPORATING THE SAME - Methods are disclosed for measuring an analyte concentration in a fluidic sample. Such methods allow one to correct and/or compensate for confounding variables such as temperature before providing an analyte concentration. The measurement methods use response information from a test sequence having at least one DC block, where the DC block includes at least one excitation pulse and at least one recovery pulse, and where a closed circuit condition of an electrode system is maintained during the at least one recovery pulse. Information encoded in the at least one recovery pulse is used to correct/compensate for temperature effects on the analyte concentration. Also disclosed are devices, apparatuses and systems incorporating the various measurement methods. | 01-07-2016 |
20160011138 | GLUCOMETER SYSTEM AND METHOD | 01-14-2016 |
20160022172 | SYSTEMS AND METHODS FOR FLUID TESTING - Implementations disclosed herein provide a method of determining a quantity of an electrochemically convertible substance in a fluid sample, the method comprising introducing the fluid sample into an electrochemical sensor, wherein at least a portion of the fluid sample is electrochemically converted to produce an electrical output from the electrochemical sensor, measuring the electrical output from the electrochemical sensor on a periodic basis to produce sensor measurements, inputting a first subset of the sensor measurements into a first computation to yield first computation analysis results, inputting a second subset of the sensor measurements and the first computation analysis results into a second computation to yield second computation analysis results, and calculating the quantity of the electrochemically convertible substance in the fluid sample by applying a third computation to the first computation analysis results and the second computation analysis results. | 01-28-2016 |
20160025672 | ELECTRONIC DEVICE FOR MEASURING BLOOD SUGAR - An operating method of an electronic device may include detecting that a strap with a blood sugar measuring device has been connected to the electronic device, receiving blood sugar related data from the blood sugar measuring device, and executing a health application based on the received data. | 01-28-2016 |
20160033439 | HAND-HELD TEST METER WITH TEST STRIP SIMULATION PASSIVE CIRCUIT BLOCK - A hand-held test meter for use with an electrochemical-based analytical test strip in the determination of an analyte in a bodily fluid sample includes a housing, a micro-controller disposed in the housing, a test strip simulation passive circuit block disposed in the housing, and a strip port connector (“SPC”) configured to operationally receive an electrochemical-based analytical test. The test strip simulation passive circuit block is in electrical communication with the SPC and the SPC is configured in electrical communication with the micro-controller. In addition, the test strip simulation passive circuit block is configured to simulate insertion of an electrochemical-based analytical test strip into the SPC and also to simulate application of a bodily fluid sample to an electrochemical-based analytical test strip inserted into the SPC by presenting one or both of (i) an alternating current (AC) load to SPC; and (ii) a direct current (DC) load to the SPC. | 02-04-2016 |
20160033440 | BLOOD GLUCOSE MEASURING DEVICE AND METHOD, AND ELECTRONIC DEVICE INCLUDING BLOOD GLUCOSE MEASURING MODULE - A method and device for measuring blood glucose are provided. The device includes a strip receiving part having a plurality of pins therein, the pins being arranged in such a manner that at least one of the pins contacts at least one electrode formed in a blood glucose measurement strip when the blood glucose measurement strip is inserted into the strip receiving part; and a controller configured to identify a type of the blood glucose measurement strip inserted into the strip receiving part and to control application of a testing voltage configured in response to the identified type of the blood glucose measurement strip to each pin of the strip receiving part. | 02-04-2016 |
20160069832 | CO-FACIAL ANALYTICAL TEST STRIP WITH STACKED UNIDIRECTIONAL CONTACT PADS - An analytical test strip (“ATT”) for use with a test meter includes a first insulating layer, with a first insulating layer upper surface, and a first electrically conductive layer (“ECL”) disposed thereon. The first ECL includes a first electrode portion (“EP”) and an electrical contact pad in electrical communication with the first EP. The ATT also includes a patterned spacer layer disposed above the first ECL that includes (i) a distal portion defining a bodily fluid sample-receiving chamber therein that overlies the first EP and (ii) an insulating proximal portion with a second ECL disposed thereon. The second ECL includes an interlayer contact portion and an electrical contact pad. A third ECL of the ATT includes a second EP and a proximal portion that overlies the interlayer contact portion. The second EP is disposed overlying and exposed to the sample-receiving chamber in an opposing relationship to the first EP. | 03-10-2016 |
20160069834 | BIOSENSOR AND MOLECULAR IDENTIFICATION MEMBER - [Problem to be Solved] Provided is a higher sensitive biosensor, in which a trace amount of non-invasively collected body fluid sample can be used, and even in a case where such a trace amount of sample is used, or even in a case where the concentration of an object substance to be measured in a sample is low, the object substance can be measured with high accuracy. [Solution] A biosensor | 03-10-2016 |
20160077039 | APPARATUS FOR DIAGNOSTIC METER STRIP CONTROL AND IDENTIFICATION - A system for measuring a property of a sample in a liquid which includes a test strip and a meter is provided. Some embodiments relate to a diagnostic test strip for collecting a sample, the strip having a plurality of electrodes for measuring a property of the sample, and the strip having a control circuit at a distal region of the strip, the control circuit configured to communicate with a controller of a meter, the control circuit including an embedded temperature sensor, a memory for lot coding and authentication of the test strip, and an inhibit logic for inhibiting the test from being used more than once; and a diagnostic meter for receiving the test strip, the meter having a controller programmed to communicate with the control circuit. | 03-17-2016 |
20160084793 | ELECTRODE REACTION AREA TESTING METHOD OF BIOSENSOR TEST STRIP - An electrode reaction area testing method of biosensor test strip includes: (1) preparing a semi-finished or finished test strip product having at least one sensing window corresponding to an electrode reaction area; a plural electrodes exposed from the electrode reaction area; (2) detecting the electrode reaction current of the electrode reaction area to obtain a first electrode reaction current and a third electrode reaction current; (3) calculating a current ratio of the first electrode reaction current to the third electrode reaction current; (4) determining the current ratio; (5) completing the detection of the electrode reaction area to determine whether the semi-finished or finished test strip product is good or defective, so as to test the accuracy of the separating plate attaching position or the insulating position and the applicability of the electrode reaction area in the manufacture of the test strip. | 03-24-2016 |
20160084795 | MEASUREMENT OF LACTIC ACID IN BIOLOGICAL FLUIDS - We propose a procedure for the determination of lactic acid or lactate in biological fluids, which is simple and low cost with respect to the known methodologies. This procedure can be used by unskilled personnel and it can be implemented in disposable test strips and portable measure devices. The procedure is based on the photochemical reaction of lactic acid with Fe(III), which is reduced to Fe(II) when irradiated with UV light. The Fe(II), produced proportionally to the amount of lactate in the sample, is determined electrochemically or using its reaction with a colored complexing agent, such as 1,10-phenanthroline, and determined by spectrophotometry. This method is advantageous both for the low cost of the reagents employed, and for their short and long term stability. | 03-24-2016 |
20170234823 | ELECTRODE ARRANGEMENTS FOR ELECTROCHEMICAL TEST ELEMENTS AND METHODS FOR USE THEREOF | 08-17-2017 |