Class / Patent application number | Description | Number of patent applications / Date published |
073610530 | Column detail | 34 |
20080202218 | LIQUID CHROMATOGRAPH AND SEPARATION COLUMN - The present invention provides a separation column and a liquid chromatograph using the separation column, which are capable of carrying out a high-speed analysis under high pressure and without a reduction in separation performance of the separation column. In the separation column, a sample and a mobile phase are introduced into a packing material. The chromatograph has a covering member for covering an outer surface of the packing material and a supporting member having the packing material covered with the covering member inserted therein, wherein the level of pressure generated within a gap located between the covering member and the supporting member on the outflow side of the gap, where the fluid is introduced, is lower than that of pressure generated within the gap on the inflow side of the gap, where the fluid flows out of the gap. | 08-28-2008 |
20090007643 | DETERMINATION OF SLURRY CONCENTRATION - A method for determining the concentration of a chromatographic medium in a liquid slurry comprises the steps of: providing a column ( | 01-08-2009 |
20090013769 | ASSAY FOR OILS - We describe a method for the detection of triacylglycerols (TAGs) in a biological sample. | 01-15-2009 |
20090071233 | Method for analyzing concentration of glue contained in electrolyte solution - The purpose of the present invention is to provide a method which makes it possible to analyze more easily the concentration of glue in an electrolyte solution, while surpressing the degradation of glue during the analysis. There is provided a method for analyzing the concentration of glue contained in an electrolyte solution containing the electrolyte components by using high performance liquid chromatography, characterized in that said method comprises a step wherein an electrolyte solution is added into the eluent pH of which has been adjusted equal to or less than 5 by adding acid to an aqueous solution of phosphate of alkaline metal or alkaline earth metal, a step wherein the eluent into which the electrolyte solution has been added is passed through a separation column the exclusion limit molecular weight of which is 4000-6000 for separating the glue and electrolyte components, and a step wherein the separated glue is detected by a detector. | 03-19-2009 |
20090145203 | PLUGGED FLOW 2D CHROMATOGRAPHY - The invention provided is a split-free nano-liter flow liquid chromatography system comprising at least a first and a second chromatographic column connected in series, wherein an autosampler is provided and programmed to inject samples and eluent solutions of increasing eluent concentration for gradually eluting analytes from the first column into the second column (without adversely affecting separation in the second column), said solutions segmented from the mobile phase of the liquid chromatography system by air plugs. | 06-11-2009 |
20090158820 | METHOD AND SYSTEM FOR DOWNHOLE ANALYSIS - Advanced remote self-contained chromatographic systems and techniques for analyzing a mixture comprising components having a wide range of boiling points. The chromatographic systems and techniques can utilize components and techniques that allow staged, simultaneous, and/or sequential vaporization of an analyte to facilitate rapid analysis. The chromatographic systems and techniques can also utilize components and techniques that focus eluents from a first separation stage prior to reduce characterization time in subsequent stages. | 06-25-2009 |
20090277254 | METHODS OF IMPROVING PACKED-BED CHROMATOGRAPHY PERFORMANCE - The invention provides methods of improving packed bed chromatography performance. | 11-12-2009 |
20090314065 | CHROMATOGRAPHY DETECTOR - A chromatography detector | 12-24-2009 |
20100005867 | TEMPERATURE ADJUSTMENT OF A FLUIDIC SAMPLE WITHIN A FLUIDIC DEVICE - A temperature control unit ( | 01-14-2010 |
20100050748 | EVALUATING HEPARIN PREPARATIONS FOR PHARMACEUTICAL USE - The disclosure features methods of analyzing preparations of heparin, and materials derived from heparin using strong anion exchange high performance liquid chromatography (SAX-HPLC). | 03-04-2010 |
20100281958 | PREPARATIVE SEPARATION/PURIFICATION SYSTEM - After a target compound is captured by an adsorbent within a trap column ( | 11-11-2010 |
20110030457 | GRADIENT-ELUTION MULTI-COLUMN SEPARATION METHOD - The invention relates to a method for separating fractions of a mixture to be separated comprising the steps of
| 02-10-2011 |
20110209531 | DESIGN OF AN IC-PROCESSED POLYMER NANO-LIQUID CHROMATORAPHY SYSTEM ON-A-CHIP AND METHOD OF MAKING IT - Embodiments in accordance with the present invention relate to packed-column nano-liquid chromatography (nano-LC) systems integrated on-chip, and methods for producing and using same. The microfabricated chip includes a column, flits/filters, an injector, and a detector, fabricated in a process compatible with those conventionally utilized to form integrated circuits. The column can be packed with supports for various different stationary phases to allow performance of different forms of nano-LC, including but not limited to reversed-phase, normal-phase, adsorption, size-exclusion, affinity, and ion chromatography. A cross-channel injector injects a nanolitre/picolitre-volume sample plug at the column inlet. An electrochemical/conductivity sensor integrated at the column outlet measures separation signals. A self-aligned channel-strengthening technique increases pressure rating of the microfluidic system, allowing it to withstand the high pressure normally used in high performance liquid chromatography (HPLC). On-chip sample injection, separation, and detection of mixture of anions in water is successfully demonstrated using ion-exchange nano-LC. | 09-01-2011 |
20110252873 | DYNAMIC THERMAL FOCUSING OF CHROMATOGRAPHIC SEPARATIONS - There is provided a method for thermally focusing the elution times of compounds of a liquid chromatography system comprising a pre-column and a separation column as well as to provide a liquid chromatography system, wherein the chromatographic separation of a mixture of substances is optimized. | 10-20-2011 |
20120006103 | ION DETECTOR AND SYSTEM - Apparatus and method for detecting current or potential generated in a liquid sample suitable for use in a chromatography or other liquid sample analytical system. One embodiment is an electrolytic ion transfer device with a signal detector in communication with the electrodes of the transfer device. Another is a combination ion transfer device/electrolyte generator. Another substitutes a detector for the ion transfer device in the combination. | 01-12-2012 |
20120011921 | METHOD FOR IMPROVING THE EFFICIENCY OF HIGH-PRESSURE LIQUID CHROMATOGRAPHY - The present invention relates to a method for improving the efficiency of high-pressure liquid chromatography columns in HPLC. More specifically, the method of the present invention provides a high-pressure liquid chromatography column being divided into a multitude of shorter separation segments, the shorter separation segments being serially connected with cooling segments. By applying an active controlled cooling action on the fluid flow passing through the cooling segments the separation efficiency of the high-pressure liquid chromatography column can be increased significantly. | 01-19-2012 |
20120079874 | Chromatography Columns - Chromatography columns are disclosed. Methods of making chromatography columns and methods of using chromatography columns are also disclosed. | 04-05-2012 |
20120096932 | Automated Sample Injection Apparatus, Multiport Valve, and Methods of Making and Using the Same - Automated sample injection apparatus, multiport valves, and chromatography systems containing an automated sample injection apparatus and/or a multiport valve are disclosed. Methods of making and using automated sample injection apparatus and multiport valves within chromatography systems are also disclosed. | 04-26-2012 |
20120103073 | Solvent Feed Systems For Chromatography Systems And Methods Of Making And Using The Same - Solvent feed systems are disclosed. Chromatography systems containing a solvent feed system are also disclosed. Methods of making and using solvent feed systems are further disclosed. | 05-03-2012 |
20120285223 | METHOD FOR DETERMINING EQUIVALENT THERMAL CONDITIONS BETWEEN LIQUID CHROMATOGRAPHY SYSTEMS - Described is a method of transferring a chromatographic method between liquid chromatography (LC) systems. The method is based on a determination of an isoretention temperature at which two solutes co-elute. The method enables separations to be performed using different LC systems with reproducible and equivalent results. For example, the method allows for a chromatography method developed for HPLC to be more readily transferred to a UPLC system and for a chromatography method developed for a UPLC system to be more readily transferred to a HPLC system. The method addresses LC systems having column ovens of different design in which the internal column temperatures are not equal although the operating temperatures of the column ovens may be accurately controlled to equal values. The retention behavior and resolution of different LC systems is caused to be substantially the same so that equivalent separation results are obtained. | 11-15-2012 |
20120318049 | COLUMN FOR CHROMATOGRAPHY, METHOD FOR PRODUCING SAME, AND ANALYSIS DEVICE - A column for chromatography includes a flow path for allowing a mobile phase, the flow path including mutually-opposing sidewalls and a bottom wall joined to the sidewalls and arranged at bottom ends of the sidewalls; and a plurality of pillars provided to extend along the sidewalls from the bottom wall and regularly arranged at a specified interval. The column is configured to separate individual components from a mixture sample containing multiple kinds of components by using the pillars as a stationary phase. Each of the pillars includes a curved outer surface and the sidewalls partially include a curved surface conforming to the outer surface of each of the pillars. The shortest distance between each of the sidewalls and a pillar positioned closest to said each of the sidewalls is equal to the shortest distance between the pillars in a flow direction of the mobile phase. | 12-20-2012 |
20130055795 | FRACTIONATION OF DE-ASPHALTED OIL OF VACUUM RESID USING PREPARATIVE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC SEPARATIONS - Two quantitative separation approaches to fractionate de-asphalted oils (DAOs) into seven classes of compounds (saturates, 1-4 | 03-07-2013 |
20130145828 | COLUMN PACKING FOR LIQUID CHROMATOGRAPHY, SEPARATION COLUMN, AND LIQUID CHROMATOGRAPHY DEVICE - To provide a column packing, a separation column, an analysis device, and an analysis method to reduce the analysis time without deteriorating the separation of multi-component amino acids. Disclosed are a column packing comprising a core portion made of a styrene-di-vinylbenzene copolymer having a cross-linkage degree of 50% or more and a shell portion made of a styrene-di-vinylbenzene copolymer having a cross-linkage degree of 20% or less; a separation column using the column packing; and a high-speed liquid chromatography analysis device and a analysis method using the separation column. | 06-13-2013 |
20130312499 | PRESSURIZABLE INJECTION SEAT - An injection device ( | 11-28-2013 |
20130340508 | MOBILE PHASE DELIVERY DEVICE AND LIQUID CHROMATOGRAPH - A mobile phase supply device comprises an aqueous path including a first delivery pump for delivering an aqueous mobile phase, an organic solvent path including a second delivery pump for delivering an organic solvent mobile phase, and a mixer for mixing mobile phases from the aqueous path and the organic solvent path, and supplying the mixture to an analysis path of a liquid chromatograph. A flow resistance between the second delivery pump and the mixer is greater than a flow resistance between the first delivery pump and the mixer. | 12-26-2013 |
20140020454 | LIQUID CHROMATOGRAPHY COLUMN, AND METHOD FOR ANALYZING HEMOGLOBIN - An object of the present invention is to provide a column for liquid chromatography that can be produced at low cost and allows suppression of non-specific adsorption of components derived from living organisms. Another object of the present invention is to provide a method for analyzing hemoglobin using the column for liquid chromatography. | 01-23-2014 |
20140033804 | NARROW BORE POROUS LAYER OPEN TUBE CAPILLARY COLUMN AND USES THEREOF - A polymer-based PLOT capillary column prepared by in situ copolymerization of a functional monomer and a crosslinking monomer, which enhances the strength of the polymer matrix, is disclosed. Also disclosed is a system comprising the polymer-based PLOT column coupled to a mass flow or concentration sensitive detector, for carrying out a chemical analysis method on samples separated by liquid chromatography using the column, and a process for using the system. Columns of the invention can be prepared in a robust fashion with a very narrow i.d., e.g., 5-15 μm. Thus, they are suitable for commercial use in ultratrace LC/MS proteomic analysis. Columns according to the invention are characterized by high resolving power and high column-to-column reproducibility. When these columns are coupled on-line with, e.g., ESI-MS detection, the resulting systems are capable of detecting the component parts of complex proteomic samples down to the low attomole to sub-attomole level. | 02-06-2014 |
20140053639 | Fitting Assemblies - A fitting assembly includes a first fitting that is configured to receive a first fluid tube and a second fitting that is configured to receive a second fluid tube. The first fitting defines a first groove. The second fitting includes a spring that is configured to engage the first groove to connect the first and second fittings such that the first and second fluid tubes are placed in fluid communication and a fluid tight seal is established between the first and second sealing fittings. | 02-27-2014 |
20140196524 | PIPE CONTAINING A METAL CASING WITH A PLASTICS MATERIAL INLAY FOR USE IN LOW AND HIGH PRESSURE APPLICATIONS, IN PARTICULAR AS AN HPLC COLUMN - A chromatography column comprises a pipe that contains a tubular metal casing with an inlay and sealing ring. The inlay is configured as a plastics material tube and is pushed or drawn into the metal casing and a sealing ring of plastics material is connected to the inlay at the end. Because of this structure, a connection to further system parts is possible, which is carry-over-free, inert on the inside, liquid-tight, optionally gas-tight, and pressure-tight. A connection element and connection connect the pipe to feed and/or discharge lines of a capillary system. Pipes, connection elements and connections of this type are advantageously used in low and high pressure systems, such as, for example, in an HPLC column. The use of such systems is advantageous in in-vitro diagnostics and in liquid handling applications. | 07-17-2014 |
20140338430 | AUTOMATED SYSTEM FOR HANDLING COMPONENTS OF A CHROMATOGRAPHIC SYSTEM - An automated system for handling components of a chromatographic system, comprising: one or more trap columns each having sorbent material therein; a robotic system for moving a trap column from a storage position to an operating position where the trap column is connected in a liquid pathway along which solvent is flowed in operation to a liquid chromatography (LC) column; and an optical sensor for sensing one or more parameters of the trap column. Sensed parameters can include: a presence or absence of a trap column in the operating position, a position or orientation of the trap column, a fluid level in the trap column, the presence and position of a sorbent material in the trap column, the condition of the trap column and/or whether the trap column is new or used. | 11-20-2014 |
20150059450 | COLUMN OVEN AND LIQUID CHROMATOGRAPH - A column oven includes a main unit, an auxiliary unit, an outside sensor, an internal sensor, a temperature range holding section for holding a plurality of temperature ranges, a temperature range specifying portion for specifying the temperature range to which the outside temperature belongs, a temperature control program holding section for holding a temperature control program for a control method of the main unit and the auxiliary unit in each temperature range in such a way that outputs of the main unit and the auxiliary unit are continuous in the temperature ranges that are adjacent to each other, a control method setting portion for setting a control method of the main unit and the auxiliary unit based on the temperature range specified and the temperature control program, and a temperature control portion for controlling the main unit and the auxiliary unit. | 03-05-2015 |
20150338383 | Frits for Chromatography - Frits for use in analytical instrument systems, including liquid chromatography systems, particularly HPLC and UHPLC systems, and methods of making and using the frits, are provided. The frits can have multiple layers, which may have different surface finishes on different surfaces. | 11-26-2015 |
20160103103 | COLUMN DEVICE FOR LIQUID CHROMATOGRAPHY AND LIQUID CHROMATOGRAPHY APPARATUS - A cylindrical column body ( | 04-14-2016 |
20160175778 | ION PROCESSING DEVICE, ION CHROMATOGRAPH PROVIDED WITH THE ION PROCESSING DEVICE, AND ELUENT GENERATOR PROVIDED WITH THE ION PROCESSING DEVICE | 06-23-2016 |