University College Dublin National University of Ireland Patent applications |
Patent application number | Title | Published |
20140213528 | Fibrosuppressant Biotherapeutics - The invention relates to IHG-1 (induced by high glucose-1) a novel gene which encodes a protein that amplifies fibrotic responses in in vitro and in vivo models of fibrotic disorders and in human diabetic nephropathy. In particular the invention relates to modifications of the IHG-1 structure which are potential fibrosuppressant biotherapeutics and modify cellular invasiveness. The invention also relates to a method of screening a therapeutic agent for suitability for the treatment of fibrotic disease comprising testing a candidate therapeutic agent for the ability to reduce the expression of IHG-1 levels in a model system. | 07-31-2014 |
20130078706 | METHOD OF TRANSFORMING CELLS - Use of an isolated | 03-28-2013 |
20100254589 | METHOD AND SYSTEM FOR IMAGE ANALYSIS - The present invention relates generally to a method for determining the level of expression of one or more candidate objects of interest in a biological sample. In particular, the present invention relates to a method for determining the level of expression of one or more candidate objects of interest using image analysis. More specifically, the present invention relates to a method and a system for determining the level of expression of one or more candidate objects of interest using an automated (computer-aided) image analysis system. | 10-07-2010 |
20100199142 | ENCODING SCHEME, AND A DECODING SCHEME USING A SERIES OF LDPC CODES BASED ON FINITE INVERSIVE SPACES - There is disclosed a method of creating an LDPC code that is defined by a parity-check matrix H. The parity-check matrix H is derived from a (0,1)-geometry which is induced by a finite inversive space. This inversive space has an order q where every circle in the inversive space contains exactly q+1 points, q is preferably even, and most preferably equal to 2. Where the inversive space has a dimension n. Where the (0,1)-geometry is formed as a derived geometric structure based on pencils of degree m≦n in the inversive space. The method includes construction of a binary K by N matrix H labelled by K circles and N pencils of the inversive space, wherein the (i, j)-entry of the matrix is 1 if circle i belongs to pencil j, and 0 otherwise. If the degree of the pencil is given by 2 then the parity-check matrix H needs to be transposed, i.e. H | 08-05-2010 |
20080255391 | Chiral Phosphorus Compounds - A process for the stereoselective preparation of a P-chiral four-co-ordinated phosphorus compound, the process comprising reacting a first reactant selected from the group consisting of a chiral alcohol, chiral amine or chiral thiol, with a second reactant comprising a P-chiral three-co-ordinated phosphorus compound, in the presence of an electrophile. | 10-16-2008 |