UNIVERSITE PIERRE ET MARIE CURIE Patent applications |
Patent application number | Title | Published |
20150057499 | MINIATURIZED SCANNING SYSTEM - A miniaturized scanning system to generate movement of a flexible device positioned at a distal part of a medical tool. The miniaturized scanning system includes an inner shaft with a longitudinal axis, adapted to guide said flexible device along the longitudinal axis, an abutment comprising an external surface and adapted to maintain said device, and a pusher mechanism adapted to engage with said abutment. The miniaturized scanning system includes at least one end portion adapted to contact said external surface of the abutment at a contact point, wherein said end portion is configured to translate along said longitudinal axis of the inner shaft and wherein the translation of said end portion results in a bending of the device in a bending plane defined by the longitudinal axis of the inner shaft and said contact point. | 02-26-2015 |
20150036021 | Multiple Scattering Medium For Compressive Imaging - A method for estimating an optical, electromagnetic or acoustic image having at least the successive steps of: scattering an incident optical, electromagnetic or acoustic signal using a multiple scattering medium corresponding to a known transmission matrix stored into a memory of an imaging system; measuring the scattered signal using a detector array and storing the measurements into the memory of the imaging system; and determining an estimated image having a number of image elements that is greater than the number of measurements, at full spatial bandwidth. The estimated image is determined from the measurements and the transmission matrix using a sparsity-promoting algorithm. | 02-05-2015 |
20150011477 | CCR2 ANTAGONIST PEPTIDES - The invention relates to a peptide comprising the following amino acid sequence Thr-Phe-Leu-Lys or Thr-Phe-Leu-Lys-Cys, useful as a CCR2 non competitive antagonist peptide. | 01-08-2015 |
20140302561 | 3S-RHAMNOSE-GLUCURONYL HYDROLASE, METHOD OF PRODUCTION AND USES - The present invention relates in particular to proteins, coding nucleic acid sequences for same, vectors comprising said coding sequences, a method for producing said proteins, and an oligosaccharide hydrolysis method using same. In particular, the invention relates to the protein of sequence SEQ ID no. 1. The present invention can be applied to the recycling of bio-natural resources formed by organisms and microorganisms including ulvans, in particular green algae. | 10-09-2014 |
20140039067 | FILAMENTOUS POLYMER PARTICLES AND USE THEREOF AS RHEOLOGY MODIFIERS - The invention relates to polymer particles in the form of filaments formed by block copolymers, as well as to the use thereof as rheology modifiers for aqueous or organic solutions. A first aspect of the invention relates to filamentous polymer particles having a length/diameter ratio greater than 100, said particles being formed by block copolymers synthesized by controlled radical emulsion polymerization in emulsion, performed using at least one hydrophobic monomer in the presence of a water-soluble marcoinitiator. The invention is characterized in that the filamentous particles are obtained in an aqueous medium for the synthesis of said block copolymers, performed by heating the reaction medium to a temperature of 60 to 120° C., the final block copolymer containing between 10 and 50 mol. % of the water-soluble macroinitiator and the hydrophobic monomer conversion rate being at least 50%. A second aspect of the invention relates to a method for modifying the rheology of an organic or aqueous solution using said filamentous polymer particle. | 02-06-2014 |
20140027346 | SPHERICAL MATERIAL COMPRISING METALLIC NANOPARTICLES TRAPPED IN A MESOSTRUCTURED OXIDE MATRIX AND ITS USE AS A CATALYST IN REFINING PROCESSES - An inorganic material is described, constituted by at least two elementary spherical particles, each of said spherical particles comprising metallic nanoparticles having at least one band with a wave number in the range 750 to 1050 cm | 01-30-2014 |
20140021096 | PROCESS FOR PREPARING A SPHERICAL MATERIAL WITH A HIERARCHICAL POROSITY COMPRISING METALLIC PARTICLES TRAPPED IN A MESOSTRUCTURED MATRIX - A process is described for the preparation of an inorganic material with a hierarchical porosity in the micropore and mesopore domains. The material has at least two elementary spherical particles having a maximum diameter of 200 microns. The process comprises:
| 01-23-2014 |
20130338315 | FILAMENTOUS POLYMER PARTICLES AND METHOD FOR PREPARING SAME BY MEANS OF CONTROLLED RADICAL POLYMERISATION IN EMULSION - The invention relates to polymer particles in the form of filaments formed by block copolymers, as well as to the method for preparing same by means of controlled radical polymerization in emulsion in the presence of a specific living macroinitiator derived from a nitroxide. The invention is characterized in that the filamentous particles are obtained in a dispersed aqueous medium by means of the synthesis of said block copolymers, performed by heating the reaction medium at a temperature of 60 to 120° C., the final block copolymer containing between 10 and 50 mol. % of the macroinitiator which is water soluble and the hydrophobic monomer conversion rate being at least 50%. According to the invention, the weight ratio of hydrophilic fraction of the filamentous particles is less than 25 wt %. | 12-19-2013 |
20130328685 | ASSISTANCE TERMINAL FOR REMOTELY MONITORING A PERSON CONNECTED TO A MEDICAL ASSISTANCE AND MONITORING DEVICE - The invention relates to an assistance terminal ( | 12-12-2013 |
20130230889 | ULVAN LYASE, METHOD FOR MANUFACTURING SAME, AND USES THEREOF - The present invention notably relates to ulvan lyases, to nucleic acid sequences coding for these ulvan lyases, to vectors comprising these coding sequences, to a method of manufacturing these ulvan lyases, as well as to a method of degrading ulvans using these ulvan lyases and applicable applications to the degradation products of the ulvans. The ulvan lyases of the present invention, or ulvanolytic protein, are notably defined as proteins of 30 or 46 kD comprising the following four sequences in their peptide sequence: PNDPNLK, LLEVGNTGTFGSTGS, DLANPDNV and WNLPE. | 09-05-2013 |
20120302517 | TET2 AS A NEW DIAGNOSTIC AND PRONOSTIC MARKER IN HEMATOPOIETIC NEOPLASMS - The present invention concerns an in vitro method for diagnosing a myeloid tumour or a lymphoid tumour in a subject, which comprises the step of analyzing a biological sample from said subject by (i) detecting the presence of a mutation in the Ten Eleven Translocation protein family member 2 gene (TET2) coding for the polypeptide having the sequence SEQ ID NO:2, and/or (ii) analyzing the expression of the TET2 gene; wherein the detection of such a TET2 mutation, of the absence of expression of TET2 or of the expression of a truncated TET2 is indicative of a subject developing or predisposed to develop a myeloid tumour or a lymphoid tumour. | 11-29-2012 |
20120149756 | TRICYCLO-DNA ANTISENSE OLIGONUCLEOTIDES, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE - Provided are tricyclo-DNA (tc-DNA) AON and methods employing tc-DNA AON for modifying splicing events that occur during pre-mRNA processing. Tricyclo-DNA (tc-DNA) AON are described that may be used to facilitate exon skipping or to mask intronic silencer sequences and/or terminal stem-loop sequences during pre-mRNA processing and to target RNase-mediated destruction of processed mRNA. Tc-DNA AON described herein may be used in methods for the treatment of Duchenne Muscular Dystrophy by skipping a mutated exon 23 or exon 51 within a dystrophin gene to restore functionality of a dystrophin protein; in methods for the treatment of Spinal Muscular Atrophy by masking an intronic silencing sequence and/or a terminal stem-loop sequence within an SMN2 gene to yield modified functional SMN2 protein, including an amino acid sequence encoded by exon 7, which is capable of at least partially complementing a non-functional SMN1 protein; and in methods for the treatment of Steinert's Myotonic Dystrophy by targeting the destruction of a mutated DM1 mRNA comprising 3′-terminal CUG repeats. | 06-14-2012 |
20120141795 | BISMUTH VANADATE PARTICLES AND THE METHOD FOR PRODUCING SAME - The subject of the invention is a method for obtaining particles of chemical formula BiVO | 06-07-2012 |
20110257176 | NITROGEN HETEROCYCLE DERIVATIVES AS PROTEASOME MODULATORS - A method for treating and/or ameliorating and/or preventing a disease or a disorder, the method comprising administering to an individual in need thereof at least one nitrogen heterocycle derivative of formula (I): | 10-20-2011 |
20110212440 | CELL SORTING DEVICE - An integrated microsystem, comprising: a microchannel, a field generator to create a magnetic field in at least one first portion of the microchannel having a direction substantially collinear with the direction of flow in the portion of the microchannel, the magnetic field also presenting a gradient, wherein the microsystem additionally comprises a detection area in fluid connection with the microchannel, | 09-01-2011 |
20110206751 | STIMULATABLE ASYMMETRICAL POLYMERSOME - The invention relates to a polymer vesicle with an asymmetrical unilamellar membrane, said membrane being constituted by two distinct layers, a layer (A) and a layer (B), said layers comprising respective amphiphilic block copolymers with layer (A) comprising, in contrast to said layer (B), an effective quantity of amphiphilic block copolymer comprising at least one stimulatable hydrophobic polymer block, said block polymers provided by said copolymers being capable of adopting a new steric configuration in response to an exogenous stimulus, conditioning the rupture of said unilamellar membrane. The invention also provides a method of producing said vesicle, a method of encapsulating an active ingredient in said vesicles, and a method of controlled release of the active ingredient. | 08-25-2011 |
20110183909 | Treatment of Mood and Anxiety Disorders - The invention relates to a selective inhibitor of Elk-1 or MSK-1 activation for use in the prevention and/or treatment of mood and anxiety disorders. | 07-28-2011 |
20110144242 | THERMOREVERSIBLY CROSSLINKED ELASTIC BITUMINOUS COMPOSITION - The disclosure relates to a bituminous composition comprising at least one bitumen and at least one organogelling molecule taken alone or as a mixture, said organogelling molecule being represented by the following general formula (I): where: A represents an acyclic, cyclic or polycyclic, saturated or unsaturated, linear or branched hydrocarbon-based group having 3 to 92 carbon atoms, resulting from the polymerization of the side chains of at least one unsaturated fatty acid, X represents an NH group or an oxygen atom O, R | 06-16-2011 |
20110033561 | USE OF PHYTOECDYSONES IN THE PREPARATION OF A COMPOSITION FOR ACTING ON THE METABOLIC SYNDROME - For reducing the negative effects of the metabolic syndrome on mammal organisms, it is proposed to use phytoecdysones for diminishing the fat body mass in individuals, notably with a weight excess. Phytoecdysones are advantageously incorporated into a food composition. The phytoecdysones can come from food plants, such as quinoa. | 02-10-2011 |
20110020928 | IMMUNOVECTORS WHICH CAN BE USED FOR THE INTRACELLULAR AND INTRANUCLEAR TRANSPORT - A method of transferring a biologically active principle of interest into a cell by coupling an antibody or a fragment of an antibody, which recognizes an epitope contained in a nucleic acid, with the biologically active principle, to form a coupled biologically active principle; and incubating the coupled biologically active principle, which is transferred through the cell membrane and into the cell, with the cell. | 01-27-2011 |
20100331327 | 7-SUBSTITUTED INDIRUBIN-3'OXIMES AND THEIR APPLICATIONS - The invention relates to new 3′-, 7-substituted-indirubins of formula (I) wherein R represents N—OH, N—O-alkyl or N—O—CO-alkyl, NO—(R | 12-30-2010 |
20100278887 | Use of a Haemoglobin for the Preparation of Dressings and Resulting Dressings - The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings. | 11-04-2010 |
20100174050 | EXPRESSION OF POLYPEPTIDES FROM THE NUCLEAR GENOME OF OSTREOCOCCUS SP - A method of producing at least one polypeptide from the nuclear genome of | 07-08-2010 |
20100116242 | METHOD OF INITIATING COMBUSTION IN AN INTERNAL COMBUSTION ENGINE, AND AN ENGINE APPLYING THE METHOD - The invention relates to a method of initiating combustion in an internal combustion engine that comprises a main chamber ( | 05-13-2010 |
20090311687 | MICROORGANISMS DETECTION AND ENUMERATION METHOD - A method for detecting and enumerating viable microorganisms, preferably selected from the group consisting of | 12-17-2009 |
20090215680 | Inhibitor peptides - The invention concerns peptides useful as MAP kinase/ERK pathway-specific inhibitors relative to a given substrate in a given subcellular compartment. | 08-27-2009 |
20090081788 | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof - An isolated DNA encoding the enzyme I-SceI is provided. The DNA sequence can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes. | 03-26-2009 |
20090079821 | STEERABLE STRUCTURE OF CATHETER OR ENDOSCOPE TYPE - A steerable structure ( | 03-26-2009 |
20080245260 | PARTICULAR NANOSTRUCTURED MATERIAL, AS PROTECTIVE COATING FOR METALLIC SURFACES - The invention relates to a novel nanostructured material comprising at least one nano-building block based on silica, alumina, zirconia, titanium oxide or cerium (IV) oxide, functionalized with at least two functionalizing agents of formula (1), (2) or (3): | 10-09-2008 |