UNIVERSITE PARIS DIDEROT - PARIS 7 Patent applications |
Patent application number | Title | Published |
20160130346 | KIR3DL2 IS A BIOMARKER AND A THERAPEUTIC TARGET USEFUL FOR RESPECTIVELY PREVENTING AND TREATING A SUBSET OF CUTANEOUS AND NON-CUTANEOUS PERIPHERAL T-CELL LYMPHOMAS - The present invention relates to a ligand molecule that specifically binds to KTR3DL2 at the surface of KTR3DL2 expressing malignant T-cells for the treatment of lymphomas. It also relates to the in vitro use of a level of expression of KIR3DL2 is a biomarker useful for diagnosing and/or monitoring a lymphoma. | 05-12-2016 |
20160015808 | TAM RECEPTORS AS VIRUS ENTRY COFACTORS - The present invention concerns the use of an inhibitor of an interaction between phosphatidylserine and a TAM receptor for preventing or treating a virus entry cofactors, in particular phosphatidylserine harboring virus infection such as flavivirus infection. | 01-21-2016 |
20150328365 | POROUS POLYSACCHARIDE SCAFFOLD COMPRISING NANO-HYDROXYAPATITE AND USE FOR BONE FORMATION - The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stent cells or growth factors. | 11-19-2015 |
20150125870 | METHOD FOR ELECTROCHEMICALLY IDENTIFYING TARGET NUCLEOTIDE SEQUENCES - A method and assembly for electrochemically identifying target nucleotide sequences. The method includes supplying a biological sample that may contain a predetermined target nucleotide sequence; supplying activatable amplification materials comprising free nucleotides to form replicated target nucleotide sequences; supplying an oxido-reducible compound capable of being inserted during replication between the nucleotides forming the replicated target sequences; and activating the activatable amplification materials before applying an electric field to the sample in order to activate the oxido-reducible compound. The replicated target sequences cause inhibition of electrochemical activity of the inserted oxido-reducible compound, and the presence of the predetermined target nucleotide sequence is determined in instances where the electric current decreases. | 05-07-2015 |
20150096899 | IRON-BASED CATALYST FOR SELECTIVE ELECTROCHEMICAL REDUCTION OF CO2 INTO CO - The present invention relates to catalysts for the production of CO gas through electrochemical CO | 04-09-2015 |
20150064110 | CROSSLINKED POLYSACCHARIDE BEADS COMPRISING AN IMAGING AGENT - The present invention relates to a method for preparing beads comprising imaging agent. The present invention further provides beads highly useful for medical imaging. | 03-05-2015 |
20140069865 | METHOD FOR HIGH-THROUGHPUT SCREENING OF DROPS BY OSMOTIC EXCHANGE AND DENSITY VARIATION - This method comprises bringing drops to be separated into contact with an interface ( | 03-13-2014 |
20140023266 | Method of Detecting and Quantifying Blur in a Digital Image - Method of detecting and quantifying blur in a digital image implementing a computer and comprising: —a step a) of obtaining a digital image; a step b) of obtaining a brightness parameter for each pixel on the basis of the digital image, the step b) comprising an operation of convolution with an edge detection matrix; a step c) of calculation of a score S1 comprising the maximum, calculated over all the pixels, of the brightness parameter obtained in step b); and a step d) a step of evaluating the digital image, the digital image being considered to be blurred if the score S1 obtained in step c) is strictly less than a first predetermined threshold, the score S1 providing a first quantity of blur present in the digital image. | 01-23-2014 |
20130344160 | IMPLANTABLE BIO-RESORBABLE POLYMER CHARGED WITH FRAGILE MACROMOLECULES - The present invention relates to a macromolecule-loaded bioresorbable crosslinked polymer wherein the polymer is obtainable from the polymerization of: (i) at least one monomer of formula (I) (CH | 12-26-2013 |
20130344159 | IMPLANTABLE SWELLABLE BIO-RESORBABLE POLYMER - The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH | 12-26-2013 |
20130344033 | RECOMBINANT PROBIOTIC BACTERIA FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY BOWEL DISEASE (IBD) AND IRRITABLE BOWEL SYNDROME (IBS) - The present invention relates to the general field of therapy of Inflammatory Bowel Disease (IBD) and/or Irritable Bowel Syndrome (IBS). Thus, the invention relates to a molecule selected from the trappin-2 protein or an active fraction thereof, a member of the WAP family proteins or an active fraction thereof or a member of the Serpin family proteins or an active fraction thereof for the treatment of Irritable Bowel Syndrome (IBS). The invention also relates to a recombinant food-grade bacterium comprising a gene selected from a gene coding for the trappin-2 protein or an active fraction thereof, a gene coding for a member of the WAP family proteins or an active fraction thereof, or a gene coding for a member of the Serpin family proteins or an active fraction thereof. | 12-26-2013 |
20130323217 | COMPOSITIONS AND METHODS FOR THE CONTROLLED REPOPULATION OF GRAM-NEGATIVE BACTERIA IN THE COLON - The present invention relates to a method for the controlled repopulation of the colonic bacterial flora. | 12-05-2013 |
20130278742 | METHOD OF OBSERVATION OF THE EMISSION OF LIGHT FROM A SAMPLE BY DYNAMIC OPTICAL MICROSCOPY - Method for observing an emission of light from a sample in a medium of refractive index nL disposed against a surface of a transparent support of refractive index nS, greater than nL, the emission of light comprising luminous components oriented toward the support and forming an angle θ and including supercritical luminous components and critical or subcritical luminous components, implementing an observation device applying filters to the signal; and transforming the signal into an image zone of the sample Modulation of the signal is carried out, in which components of the emission of light are allowed to pass through so as to obtain image zones, the modulation pertaining to all or some of the collected signals; and at least one useful image zone of the sample is produced by combining image zones, the combination evidencing differences between the image zones related to the modulation. | 10-24-2013 |
20130171126 | CROSSLINKED POLYSACCHARIDE BEADS AND THEIR BIOMEDICAL USES - The present inventions relates to beads as biocompatible material adapted for use within the human or animal body. Said beads are highly useful for tissue engineering, in situ tissue regeneration, as well as for drug and/or cells delivery. In addition, said beads may support biotechnological applications such as cell carriers. | 07-04-2013 |
20130053336 | TREATMENT OF CHLAMYDIACEAE INFECTIONS BY MEANS OF BETA-LACTAMS - The invention relates to a method for treating infections of bacteria of the | 02-28-2013 |
20130031981 | IMAGING METHOD AND APPARATUS USING SHEAR WAVES - An imaging method using shear waves for observing a viscoelastic medium, comprising: | 02-07-2013 |
20120230937 | IMPLANTABLE BIO-RESORBABLE POLYMER - The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH | 09-13-2012 |
20120220856 | METHOD FOR QUANTIFYING THE DEVELOPMENT OF PATHOLOGIES INVOLVING CHANGES IN THE VOLUMES OF BODIES, NOTABLY TUMORS" - A method for quantifying the development of pathologies involving changes in volume of a body represented via an imaging technique, including normalizing gray levels by a midway technique for two images I | 08-30-2012 |
20120171705 | COMBINATION OF SPLA2 ACTIVITY AND OXPL/APOB CARDIOVASCULAR RISK FACTORS FOR THE DIAGNOSIS/PROGNOSIS OF A CARDIOVASCULAR DISEASE/EVENT - The use of a combination of sPLA2 activity and OxPL/apoB cardiovascular risk factors for the diagnosis/prognosis of a cardiovascular disease/event or for the monitoring of a cardiovascular disease. | 07-05-2012 |
20120058936 | COMPOSITIONS AND METHODS FOR ELIMINATION OF GRAM NEGATIVE BACTERIA - Oral drug delivery formulations which specifically administer antibacterial agents to the ileum, caecum, and/or the colon, without significant administration elsewhere in the gastrointestinal tract, are disclosed. The formulations include, as actives, a combination of a macrolide or aminoglysoside, or quinolone antibacterial and an anti-Gram-negative lipopeptide (polymyxin) antibacterial agent or other peptide antibacterials effective against Gram-negative bacteria. The formulations can be used to treat infections or unwanted colonization in the colon, and to provide effective decontamination of the colonic flora from unwanted or potentially pathogenic bacteria. | 03-08-2012 |
20110229919 | COMBINATION OF SPLA2 ACTIVITY AND OXPL/APOB CARDIOVASCULAR RISK FACTORS FOR THE DIAGNOSIS/PROGNOSIS OF A CARDIOVASCULAR DISEASE/EVENT. - A method of identifying a subject having or at risk of having or developing a cardiovascular disease and/or a cardiovascular event, includes:
| 09-22-2011 |
20110229900 | METHOD FOR DETECTING MICROORGANISMS OF KINGELLA GENUS - The invention relates to a method for detecting Kingella microorganisms through PCR of a chaperonin gene. | 09-22-2011 |
20110188717 | METHOD AND DEVICE FOR READING AN EMULSION - A method for reading an emulsion ( | 08-04-2011 |
20110136685 | METHOD FOR DETERMINING A PREDISPOSITION TO BASAL CELL CARCINOMA AND FOR SCREENING TREATMENTS THEREOF - The present invention relates to methods for detecting a predisposition to a basal cell carcinoma and methods for screening a treatment of a basal cell carcinoma. | 06-09-2011 |
20110124723 | Compounds for Preventing and Treating Plasmodium Infections - The present invention relates to the use of at least one compound of formula (I) for the manufacture of a medicament intended for preventing or treating infections by a | 05-26-2011 |
20110028838 | Method and Apparatus for Measuring a Physical Parameter in Mammal Soft Tissues by Propagating Shear Waves - Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed on the basis of these values. | 02-03-2011 |
20110014691 | METHOD FOR GENERATING PRIMATE CARDIOVASCULAR PROGENITOR CELLS FOR CLINICAL USE FROM PRIMATE EMBRYONIC STEM CELLS OR EMBRYONIC-LIKE STATE CELLS, AND THEIR APPLICATIONS - The present invention is directed to a method for the in vitro preparation of cardiovascular progenitors cells from mammalian embryonic stem cells (ES cells) or mammalian embryonic-like state cells, preferably from primate, wherein said method comprises the use of the CD15 (SSEAI) marker as a positive cardiovascular progenitors differentiation marker. The present invention also claimed the use of a receptor tyrosine kinase inhibitor, particularly the SU5402 or SU11248 in association with the BMP2 for improving the efficiency of the desired differentiation. The present invention is also directed to the use of platelet lysate as foetal animal serum substitute in a culture medium intended to the proliferation or propagation of primate ES cells maintaining their pluripotency feature. Derived compositions or kits in relation with the claimed methods or product obtainable by the claimed methods form also part of the present invention. | 01-20-2011 |
20100303724 | Polypeptides, Cyclic Polypeptides and Pharmaceutical Comprising Thereof for Non Invasive Specific Imaging of Fibrosis - The present invention relates to diagnostic imaging and in particular to the diagnostic imaging of fibrosis. More particularly, the present invention provides a polypeptides, cyclic polypeptides and pharmaceutical compositions suitable for the non-invasive visualization of fibrosis. The polypeptide of the invention may comprise an amino acid sequence consisting of: X1-X2-M-H-G-L-X7-L-X9-X10-D-E wherein amino acid X1 is R, F or P; amino acid X2 is F or V; amino acid X7 is Q, H or L; amino acid X9 is W or G and amino acid X10 is A or D. | 12-02-2010 |