The University of Tokushima Patent applications |
Patent application number | Title | Published |
20150335610 | PDK4 INHIBITOR AND USE THEREOF - The purpose of the present invention is to provide a therapeutic agent or preventive agent for exacerbation of influenza, specifically to provide a novel pyruvate dehydrogenase kinase 4 (PDK4) inhibitor. The present invention relates to a PDK4 inhibitor, medical composition or cosmetic composition containing as the active ingredient a compound represented by any one of the following general formulas (I) through (III) and a pharmaceutically acceptable ester derivative thereof, or a pharmaceutically acceptable salt of the same. | 11-26-2015 |
20150241568 | DEVICE FOR MEASURING RADIATION INTENSITY OF SMALL SEALED RADIATION SOURCE FOR CANCER THERAPY - Provided is a radiation intensity measuring apparatus for each of small sealed radiation sources for cancer therapy capable of measuring multiple cartridges efficiently and rapidly. | 08-27-2015 |
20150216801 | STABLE OXALIPLATIN-ENCAPSULATING LIPOSOME AQUEOUS DISPERSION AND METHOD FOR STABILIZING SAME - An object of the present invention is to provide an oxaliplatin-encapsulating liposome aqueous dispersion that has excellent long-term storage stability. The present invention provides an aqueous dispersion of liposomes encapsulating oxaliplatin, the oxaliplatin-encapsulating liposome aqueous dispersion containing 2-morpholinoethanesulfonic acid in an external aqueous phase. | 08-06-2015 |
20150152163 | PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING SAME - An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with β-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method. | 06-04-2015 |
20140287412 | ACF DETECTION METHOD - The present invention provides a method for detecting ACF by analyzing a test region of large intestine tissue at the molecular level. Namely, the present invention relates to a method for detecting aberrant crypt foci (ACF) that comprises detecting an ACF detection marker in a test region of large intestine tissue, by using one or more types of molecules for which ACF-specific expression increases as the ACF detection marker, the molecule being selected from the group consisting of SLC2a1, and SLC7a7; an ACF detection marker for detecting the ACF in human-derived large intestine tissue, that is SLC2a1, or SLC7a7; and, a method for evaluating risk of colorectal cancer and colorectal adenoma in subjects based on the results of detecting ACF in a test region of large intestine tissue of the subjects using the aforementioned ACF detection method. | 09-25-2014 |
20140213522 | PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING SAME - An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with β-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method. | 07-31-2014 |
20140162952 | ERAP1-DERIVED PEPTIDE AND USE THEREOF - Provided is a novel cancer-treating agent which can be used as a novel choice for the treatment of cancer. Specifically provided are: a peptide that inhibits binding of ERAP1 polypeptide to PHB2 polypeptide, which comprises a binding site of the ERAP1 polypeptide to the PHB2 polypeptide, and a pharmaceutical composition comprising the peptide. In addition, provided is a method for screening a drug candidate for treating and/or preventing cancer using inhibition of the binding of the ERAP1 polypeptide to PP1α polypeptide, PKA polypeptide or PKB polypeptide as an index. | 06-12-2014 |
20140094521 | BENZYLAMINE DERIVATIVE - The objective of the present invention is to provide a new compound which is effective in treating blood cancer, particularly multiple myeloma, and which is also effective in suppressing an SP cell, i.e. Side Population Cell, which is a cause of recurrence of cancer. The compound according to the present invention is a novel compound which has the specific benzylamine structure. | 04-03-2014 |
20140093960 | CELL DIFFERENTIATION INDUCER AND DIFFERENTIATION INDUCING METHOD - The objective of the present invention is to provide a cell differentiation inducer which is a low-molecular compound, which can be chemically synthesized easily and which can efficiently induce a differentiation of an undifferentiated cell into a nervous system cell with high selectivity. In addition, the objective of the present invention is to provide use of a specific catechol derivative for efficiently inducing a differentiation of an undifferentiated cell into a nervous system cell with high selectivity, and a method for efficiently inducing a differentiation of an undifferentiated cell into a nervous system cell with high selectivity using a specific catechol derivative. The cell differentiation inducer of the present invention is characterized in comprising the catechol derivative having the specific chemical structure. | 04-03-2014 |
20130344530 | METHOD FOR SCREENING SUBSTANCE RELATING TO ENDOPLASMIC RETICULUM STRESS PARTICIPATING IN ONSET OF DIABETES - An object of the present invention is to provide a system for evaluating activation of the pathway mediated by ATF6. More specifically, an object of the present invention is to provide a method for screening an endoplasmic reticulum stressor, as well as a method for screening a substance for suppressing an endoplasmic reticulum stress induced by the activation of the pathway mediated by ATF6, and a method for screening an antidiabetic drug candidate. As a result of extensive research, the inventors of the present invention found a method for real-time evaluation of activation of the pathway mediated by ATF6 in viable cells with a high degree of sensitivity. The method uses a nonfluorescent peptide domain derived from a fluorescent protein and a polynucleotide encoding the ATF6 protein domain. | 12-26-2013 |
20130344081 | METHOD OF TREATING AMYOTROPHIC LATERAL SCLEROSIS - Problem: An object of the present invention is to provide a drug effective for the treatment of ALS, or a method for treating ALS. | 12-26-2013 |
20130323375 | METHOD FOR STERILIZING FRUITS AND VEGETABLES - A method for sterilizing fruits and vegetables includes irradiating a surface of fruits and vegetables with UVA, while the surface of the fruits and vegetables is in contact with chlorine water containing sodium hypochlorite having a chlorine concentration of 5 ppm or more. According to the method for sterilizing fruits and vegetables, the fruits and vegetables can be quite efficiently sterilized by chlorine water having a quite low concentration, that is 5 ppm or more, slightly higher than that of tap water. Further, multiplication of bacteria in the sterilized fruits and vegetables can be effectively prevented, while a residual chlorine concentration in the sterilized fruits and vegetables is significantly reduced. | 12-05-2013 |
20130243880 | PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING SAME - An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with β-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method. | 09-19-2013 |
20130170513 | LASER BEAM ENERGY STABILIZING APPARATUS, PULSE TEMPORAL WAVEFORM CONTROL APPARATUS, LASER BEAM ENERGY STABILIZING METHOD, AND PULSE TEMPORAL WAVEFORM CONTROL METHOD - The present invention provides a laser beam control apparatus including: beam optical systems | 07-04-2013 |
20130071866 | METHOD FOR TESTING THE SEVERTIY OF AN ILLNESS - An object of the present invention is directed to a method for assaying the severity of an illness in real time and is to provide a testing method capable of assessing the severity of an illness in more detail than the conventional APACHE II and SOFA scores. The established method can accurately measure an ATP level in a sample, thereby accurately and quickly deducing the “state of intracellular energy required for living organisms” from the ATP level, and by extension, determining the severity of an illness. The present invention further provides a novel biomarker ATP-lactate energy risk score (A-LES) value that is capable of determining the severity of an illness by the reevaluation, with the ATP concentration as an index (specifically, on the basis of a lactic acid level (mM)/ATP concentration (mM) ratio), of the level of lactic acid that accumulates in the sample due to the breakdown of in vivo metabolic balance accompanied by the increased severity of the illness. The present invention also provides a novel biomarker ATP-ketone energy risk score (A-KES) value that is capable of determining the severity of an illness by the reevaluation of a ketone body level in the sample with the ATP concentration as an index (specifically, on the basis of a ketone body level (mM)/ATP concentration (mM) ratio). | 03-21-2013 |
20130044931 | CAROTID-ARTERY-PLAQUE ULTRASOUND-IMAGING METHOD AND EVALUATING DEVICE - The carotid artery plaque properties are quantitatively determined by a carotid artery echo whereby predicting incidence of cerebral infarction or myocardial infarct. A method includes obtaining, coloring, and displaying steps. In the obtaining step, the integrated amounts per unit time of echo signals corresponding to pixels of an echo image of carotid artery plaque are obtained. The signals are obtained when the image is obtained by an IBS method. In the coloring step, the relationship between ranges and colors is referenced. The available full range of the integrated amount is previously divided into the ranges. The colors are assigned to the ranges. The pixels are classified into the ranges in accordance with the integrated amounts corresponding to the pixels. The pixels of the image are colored in colors corresponding to the ranges of the pixels. In the displaying step, the colored echo image is displayed on a display portion | 02-21-2013 |
20120220005 | METHOD FOR PRODUCING ETHANOL FROM LIGNOCELLULOSIC BIOMASS - An object of the invention is to provide an inexpensive and efficient ethanol production method using lignocellulosic biomass as a raw material. | 08-30-2012 |
20120203027 | PROCESS FOR PREPARATION OF DIETHYLENETRIAMINEPENTAACETIC ACID DERIVATIVE, AND DIETHYLENETRIAMINEPENTAACETIC ACID DERIVATIVE - The objective of the present invention is to provide a process for simple and efficient preparation of an intermediate compound to synthesize a gadolinium complex having a substituent for improving a retention property in blood time and specificity to an intended organ. The objective of the present invention is also to provide an intermediate compound produced by the said production process. The process for preparation of the diethylenetriaminepentaacetic acid derivative (I): | 08-09-2012 |
20120195838 | ORAL COMPOSITION FOR DENTURE WEARERS - Provided is an oral composition for denture wearers, which includes an antimicrobial substance of biological origin, is biocompatible, and has an antimicrobial activity. Specifically, provided is an antimicrobial oral composition for denture wearers including a component of common rush origin. The oral composition for denture wearers is placed in the mouth, and hence the oral composition for denture wearers including a component of common rush origin, which may also be used as a food additive, is safe for a living body and useful. | 08-02-2012 |
20120035632 | ALLOY FOR MEDICAL USE AND MEDICAL DEVICE - Provided is alloy for medical use and a medical device that is novel and useful. The alloy for medical use according to, for example, an embodiment of the present invention is mainly composed of three kinds of elements of gold (Au), platinum (Pt), and niobium (Nb). A total content of the three kinds of elements can be no smaller than 99% by weight, in which a platinum content can be no smaller than 5% by weight and no greater than 50% by weight and a niobium content can be no smaller than 3% by weight and no greater than 15% by weight. By adjusting the content ratio of the three elements, for example, it is possible to reduce or prevent artifacts in an MRI. Non-magnetization is also possible. | 02-09-2012 |
20110282004 | POLYFUNCTIONAL POLYMER OF HIGH STEREOREGULARITY AND METHOD FOR PRODUCING THE SAME - This invention provides a polyfunctional polymer having high stereoregularity, in particular, isotacticity, and provides a production process thereof. The present invention relates to a polymer having, in a molecule, a repeating unit represented by General Formula (2): | 11-17-2011 |
20110226966 | OUTDOOR WATER TREATMENT APPARATUS TO KILL BACTERIA WITH ULTRAVIOLET LIGHT - Bacteria in water | 09-22-2011 |
20110211741 | EVALUATION APPARATUS OF FLUORESCENCE POPULATION, EVALUATION METHOD OF FLUORESCENCE POPULATION AND COMPUTER READABLE STORAGE MEDIUM - Statistical data of a fluorescence population is obtained easily with high accuracy. To achieve this, an evaluation apparatus of fluorescence population of the present application includes an input unit inputting a fluorescence observation image (If) of a fluorescence population and a transillumination observation image (It) having a same field of view as the fluorescence observation image, a first detecting unit (Mt) detecting, as a first area, an area in which a cellular image exists on the transillumination observation image being input, a setting unit (If′) setting, as a reference area, an area corresponding to the first area on the fluorescence observation image being input, and an obtaining unit obtaining fluorescence intensity data of a fluorescence image from the reference area in the fluorescence observation image. | 09-01-2011 |
20110189671 | NUCLEOSIDE TRIPHOSPHATE DERIVATIVE, NUCLEIC ACID PROBE, MULTILABELED NUCLEIC ACID PROBE, METHOD FOR PRODUCTION OF MULTILABELED NUCLEIC ACID PROBE, AND METHOD FOR DETECTION OF TARGET NUCLEIC ACID - A novel nucleoside triphosphate derivative, a nucleic acid probe, and a multilabeled nucleic acid probe that can detect a target nucleic acid conveniently and with high sensitivity, as well as a method for producing the multilabeled nucleic acid probe, and a method for detecting a target nucleic acid using the multilabeled nucleic acid probe or the nucleic acid probe. A target nucleic acid can be detected conveniently and with high sensitivity by using a transglutaminase (TGase), and by using a multilabeled nucleic acid probe in which a plurality of labeling portions have been introduced in advance by covalent binding, or by introducing a plurality of labeling portions by covalent binding into a nucleic acid probe that has been hybridized with the target nucleic acid. | 08-04-2011 |
20100330582 | METHOD FOR PRODUCTION OF NOVEL NANO SILICA PARTICLE AND USE OF THE NANO SILICA PARTICLE - The present invention presents a silica particle containing at least one silica compound selected from a group consisting of mercapto-propyl-trimethoxysilane (MPS), mercapto-propyl-triethoxysilane (MPES), mercapto-propyl-methyldimethoxysilane (MPDMS), trimethoxy[2-(7-oxabicyclo[4.1.0]-hepto-3-yl)ethyl]silane(EpoPS), thiocyanatopropyltriethoxysilane (TCPS), and acryloxypropyltrimethoxysilane (AcPS), which can be provided and utilized as a label, a marker, or the like for qualitative test and quantitative test for such as prophylactic agent, therapeutic agent, diagnostic agent, diagnostic and therapeutic agent or the like in dental, medical and veterinary fields regardless of fields. | 12-30-2010 |
20100330166 | AGENT FOR ENHANCING ANTI-TUMOR EFFECT COMPRISING OXALIPLATIN LIPOSOME PREPARATION, AND ANTI-TUMOR AGENT COMPRISING THE LIPOSOME PREPARATION - An object of the present invention is to further enhance the antitumor effect when oxaliplatin is administered in combination with a combination drug containing tegafur, gimeracil and oteracil potassium. According to the present invention, by using oxaliplatin encapsulated in a liposome preparation, combination therapy of oxaliplatin plus a combination drug containing tegafur, gimeracil and oteracil potassium, is revealed to show remarkably enhanced antitumor effect without increasing side effects. | 12-30-2010 |
20100310872 | NANOFUNCTIONAL SILICA PARTICLES AND MANUFACTURING METHOD THEREOF - Provided are nanofunctional silica particles having excellent functionality and quality, and capable of being mass-produced at low costs. According to the present invention, there are provided nanofunctional silica particles including a coating layer containing one or more silica compounds selected from the group consisting of mercaptopropyl trimethoxysilane (MPS), mercaptopropyl triethoxysilane (MPES), mercaptopropyl methyldimethoxysilane (MPDMS), trimethoxy[2-(7-oxabicyclo[4.1.0]-hept-3-yl)ethyl]silane (EpoPS), thiocyanatopropyl triethoxysilane (TCPS), acryloxypropyl trimethoxysilane (ACPS), and aminopropyl trimethoxysilane (APS); and functional particles in the coating layer, and being used in imaging, assay, diagnosis, treatment or the like, medicine or bioresearch. | 12-09-2010 |
20100226157 | POWER CONVERSION CONTROL DEVICE, POWER CONVERSION CONTROL METHOD, AND POWER CONVERSION CONTROL PROGRAM - In the present invention, when configuring a control system of an inverter performing power conversion between AC and DC, a frequency computation is performed based on biaxial voltage amounts obtained through two current regulators in such a way that each of biaxial component currents obtained by detecting an AC circuit current and performing a rotational coordinate transformation matches each respective command value and phase information in synchronization with an electromotive force power supply of the AC circuit is obtained by integrating the frequency to perform the rotational coordinate transformation of the AC current and also the inverter is caused to operate by generating a PWM switching signal from the biaxial voltage amounts to perform necessary power conversion control. | 09-09-2010 |
20100208762 | LASER DIODE HAVING NANO PATTERNS AND METHOD OF FABRICATING THE SAME - A laser diode having nano patterns is disposed on a substrate. A first conductive-type clad layer is disposed on the substrate, and a second conductive-type clad layer is disposed on the first conductive-type clad layer. An active layer is interposed between the first conductive-type clad layer and the second conductive-type clad layer. Column-shaped nano patterns are arranged at a surface of the second conductive-type clad layer to form a laser diode such as a distributed feedback laser diode. | 08-19-2010 |
20100197765 | METHOD FOR PROMOTING THE EXPRESSION OF P53, AND P53 EXPRESSION PROMOTER FOR USE IN THE METHOD - A method for promoting expression of p53 mRNA and an expression promoting agent for use in the method are provided. The expression of the p53 gene can be promoted by inhibiting the binding between RNA transcribed from exon 1 of the vegf-A gene and mRNA transcribed from the p53 gene. The inhibition of the binding can be achieved by, for example, degrading the RNA transcribed from the exon 1 of the vegf-A gene, inhibiting transcription of RNA from the exon 1 of the vegf-A gene, or binding a nucleic acid that is different from the mRNA transcribed from the p53 gene to the RNA transcribed from the exon 1 of the vegf-A gene. | 08-05-2010 |
20100183202 | BRAIN-IMAGE DIAGNOSIS SUPPORTING METHOD, PROGRAM, AND RECORDING MEDIUM - To provide a brain-image diagnosis supporting method or the like. The method is a statistical evaluation method excluding the subjective judgment of an examiner, and enables image diagnosis. The method can present stable judgment criteria with respect to data on brain images imaged by a predetermined method in order to discriminate difficult diseases to diagnose. The method is also effective with respect to relationships which can not be always explained with a simple linear relationship, for example, the relationship between data on brain images imaged by a predetermined method and a disease which is a variable. By applying a predetermined nonlinear multivariate analysis method to data on brain images of a plurality of examinees imaged by a predetermined method and by classifying the data, image diagnosis support using a computer performed with respect to the data on brain images is performed. For example, SOM method is applied as a predetermined nonlinear multivariate analysis method. Data on brain images of a plurality of examinees imaged by SPECT or the like are handled as input data vectors x, which are presented to neurons on a two-dimensional lattice array in the SOM method so as to perform image diagnosis support based on the two-dimensional SOM after a predetermined training length. | 07-22-2010 |
20100086939 | DETERMINATION METHOD FOR ALLERGIC DISEASE - It is to provide a method for determining allergic diseases with a high sensitivity and accuracy which enables multilateral and global analysis with a minute amount of sample, even using body fluid other than blood such as saliva, nasal discharge and tears as a sample, particularly by suppressing nonspecific reaction as much as possible. A chemically modified diamond/DLC (Diamond-like Carbon) chip is activated with a reacting reagent, a coupling reaction with a peptide comprising allergen or allergen epitope is conducted, and a sample such as saliva, tears, and nasal discharge which has undergone pressure filtration with a low protein-adsorbing filter, is contacted with an allergen determination chip to which washing and blocking operations have been performed on unreacted active groups, and an allergen recognizing antibody in the sample captured by the allergen determination chip is detected by immunoassay using a labeled secondary antibody, wherein a glycine-containing solution is used for a washing solution and/or blocking solution used in the washing and blocking operations, is used. | 04-08-2010 |
20100062945 | Nb3Sn SUPERCONDUCTING WIRE, PROCESS FOR PRODUCING THE SAME, AND SINGLE-CORE COMPOSITE WIRE USED IN PRODUCTION OF Nb3Sn SUPERCONDUCTING WIRE | 03-11-2010 |
20100062454 | Method for predicting risk of acquiring influenza - An object of the present invention is to provide a method for predicting the risk of acquiring influenza, which is characterized by low price, low invasiveness, and applicability to total automation. The present invention provides a method for predicting the risk of acquiring influenza, which comprises measuring the ratio of anti-influenza IgA to the total IgA in a specimen collected from a subject. | 03-11-2010 |
20100055883 | GROUP III-NITRIDE SEMICONDUCTOR THIN FILM, METHOD FOR FABRICATING THE SAME, AND GROUP III-NITRIDE SEMICONDUCTOR LIGHT EMITTING DEVICE - Disclosed herein is a high-quality group III-nitride semiconductor thin film and group III-nitride semiconductor light emitting device using the same. To obtain the group III-nitride semiconductor thin film, an AlInN buffer layer is formed on a (1-102)-plane (so called r-plane) sapphire substrate by use of a MOCVD apparatus under atmospheric pressure while controlling a temperature of the substrate within a range from 850 to 950 degrees Celsius, and then, GaN-based compound, such as GaN, AlGaN or the like, is epitaxially grown on the buffer layer at a high temperature. The group III-nitride semiconductor light emitting device is fabricated by using the group III-nitride semiconductor thin film as a base layer. | 03-04-2010 |
20090280094 | Treatment of Ischemic Diseases Using Erythropoietin - Disclosed is a method for stimulating revascularization in a subject comprising the steps of:
| 11-12-2009 |
20090202619 | POLYOXYALKYLENE CHAIN-CONTAINING LIPID DERIVATIVE AND LIPID FILM STRUCTURE CONTAINING SUCH DERIVATIVE - A polyoxyalkylene chain-containing lipid derivative, which is represented by the following formula (1): | 08-13-2009 |
20090192794 | Digital filtering method, digital filtering equipment,digital filtering program, and recording medium and recorded device which are readable on computer - Included in the digital filtering equipment for extracting a feature quantity from a speech signal in order to execute a speech recognition based on an inputted speech signal are: a) an waveform determining section for obtaining an inputted speech signal and quantizing the speech signal waveform; b) a division value operating section for summing a quantized signal data in a prescribed adjoining region to divide the summation value by the number of summed data, with respect to a data quantized at each point by the waveform determining section, whereby a division value is obtained with the data being centered; c) a comparison section for comparing a division value calculated by the division value operating section and the quantized data calculated in the division value operating section to output logical truth of a comparison result, with respect to each data; and d) a conversion section for converting the quantized data into the selected data points based on an output from the comparison section. Thus, the feature quantity can be extracted only by applying an integer summation and comparison operation, so that performance of arithmetic operation is extremely simplified to be fast and inexpensive. | 07-30-2009 |
20090092165 | LASER DIODE HAVING NANO PATTERNS AND METHOD OF FABRICATING THE SAME - A laser diode having nano patterns is disposed on a substrate. A first conductive-type clad layer is disposed on the substrate, and a second conductive-type clad layer is disposed on the first conductive-type clad layer. An active layer is interposed between the first conductive-type clad layer and the second conductive-type clad layer. Column-shaped nano patterns are arranged at a surface of the second conductive-type clad layer to form a laser diode such as a distributed feedback laser diode. | 04-09-2009 |
20090069654 | BIODEVICE, CONTACT PART STRUCTURE OF BIODEVICE, AND BIOSENSOR - A biodevice is in an elongated form and has a conductive layer and an insulating layer stacked on a side surface of a shaft member at the center. A cylindrical hollow section is formed through the device, being connected to the exterior at a front end and extending from this front end axially. An electrode section is formed on an inner surface. A sensing substance such as enzyme may be placed at the electrode section to detect a current value corresponding to the concentration or quantity of an object under test placed between a counter electrode and the biodevice. | 03-12-2009 |
20090068639 | System and method of quantitatively determining a biomolecule, system and method of detecting and separating a cell by flow cytometry, and fluorescent silica particles for use in the same, and kit comprising plural kinds of the silica particles in combination - A system of quantitatively determining a biomolecule, which has: allowing fluorescent silica particles capable of emitting fluorescence detectable by a flow cytometer to capture a target biomolecule fluorescent-labelled for quantitative determination; detecting the fluorescence emitted from the fluorescent silica particles themselves by using the flow cytometer; and measuring the intensity of the fluorescence of the labelled target biomolecule, thereby quantitatively determining the target biomolecule. | 03-12-2009 |
20090022687 | Novel Pharmaceuticals That Use Anti-HLA Antibodies - The present inventors tested the effects of interferons on the expression of HLA-A in cells and cell injury caused by anti-HLA class I antibodies, by using a 2D7-DB antibody as an anti-HLA class I antibody and the IM-9 cell line as the cells to be tested. As a result, the expression of HLA-A was demonstrated to be upregulated by IFNα or IFNγ, Furthermore, WST-8 assays were performed to examine the cell viability when an interferon and an anti-HLA class I antibody were used in combination. As a result, cell death activity was found to be increased by the combination of 2D7-DB and IFNα or IFNγ. | 01-22-2009 |
20080293584 | Fluorescent silica nano-particle, fluorescent nano-material, and biochip and assay using the same - Colloidal silica particles containing a fluorescent dye compound, composed of a silica particle containing a silica component and a fluorescent dye compound chemically bound or adsorbed thereto, | 11-27-2008 |