Seoul National University Hospital Patent applications |
Patent application number | Title | Published |
20140171489 | HUMAN RESISTIN RECEPTOR AND USE THEREOF - The present invention concerns a human resistin receptor. More particularly, the present invention provides a method for screening a receptor of human resistin protein, a method for preventing or treating an inflammatory disease and arteriosclerosis using an expression- or activity-regulator for a human resistin receptor, and a pharmaceutical composition including an expression- or activity-regulator for the human resistin receptor. The method for screening a human resistin protein receptor according to the present invention enables separation of a receptor which directly binds to resistin from human monocyte, reveals a mechanism of signal transduction of the resistin receptor, and therefore, is expected to contribute to regulation of an inflammatory effect of monocyte, molecular detection of causes for vascular inflammation and arteriosclerosis, and developments of prevention and a treating agent for an inflammatory disease and arteriosclerosis. | 06-19-2014 |
20140011275 | COMPOSITION FOR SUSPENSION CULTURING OF STEM CELLS - The present invention relates to a composition for suppressing the death of stem cells during suspension culturing, a composition for mass culturing of stem cells, and a method for suppressing cell death of stem cells during suspension culturing. The composition of the present invention can be usefully used for effective single suspension culturing of stem cells, particularly, mesenchymal stem cells, or used for mass suspension culturing under the circumstances in which cell aggregation does not occur. | 01-09-2014 |
20130028873 | METHOD FOR INCREASING ACTIVITY IN HUMAN STEM CELL - Provided are a method for preparing a highly active human mesenchymal stem cell, which includes forming a spherical cell aggregate by cultivating human mesenchymal stem cells against gravity; a highly active stem cell prepared thereby; a cell therapeutic agent including the stem cell aggregate; and a method for forming a spherical cell aggregate by cultivating human mesenchymal stem cells, wherein the amount of E-cadherin in the mesenchymal stem cell is increased during the cultivation. | 01-31-2013 |
20120015383 | NOVEL DIAGNOSTIC MARKER FOR TYPE 1 DIABETES MELLITUS - The present invention provides, as a novel diagnosis marker for type 1 diabetes mellitus, a type 1 diabetes mellitus diagnostic composition comprising alanyl-tRNA synthetase, glycyl-tRNA synthetase, asparaginyl-tRNA synthetase, or tryptophanyl-tRNA synthetase, a diagnostic kit comprising the same, and a diagnostic method using the same. The composition, the kit, and the method, according to the present invention, may be used for early diagnosis and confirmed diagnosis of type 1 diabetes mellitus because type 1 diabetes mellitus can be easily diagnosed from a patient sample. | 01-19-2012 |
20110256626 | METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS WITH HIGH EFFICIENCY AND INDUCED POLURIPOTENT STEM CELLS PROUCED THEREBY - The present invention provides a method for producing customized pluripotent stem cells. Specifically, the present invention comprises following steps: extracting proteins from any of the dedifferentiated stem cells or induced pluripotent stem cells, the said dedifferentiated or pluripotent stem cells being prepared by any known method; introducing the protein extract into the adult somatic cells; and culturing the adult somatic cells to produce pluripotent stem cells having the same pluripotency as that of embryonic stem cells. In addition, pluripotent stem cells produced according to the present method and cell therapeutics comprising the same are provided. The method allows pluripotent stem cells to be produced very easily and at a significantly higher yield, compared to typical methods. | 10-20-2011 |
20110142809 | METHOD FOR SEPARATING HIGHLY ACTIVE STEM CELLS FROM HUMAN STEM CELLS AND HIGHLY ACTIVE STEM CELLS SEPARATED THEREBY - The present invention relates to a method for separating highly active stem cells from human stem cells, the highly active stem cells separated by the method, a cell therapeutic agent containing the stem cells, and a medium for separating the highly active stem cells from stem cells containing a specific cytokine. According to the present invention, the method is useful for separating the highly efficient stem cells from mesenchymal stem cells of various origins. Further, the method is very useful in developing a cell therapeutic agent of high efficiency because the method can be applicable to stem cells of various origins which are cultured under different conditions. Senescent stem cells increased by several passage times in vitro can be effectively sorted out, so the method can be used for reactivating the stem cells. | 06-16-2011 |
20110087210 | MAGNETICALLY-COUPLED BIPOLAR RADIOFREQUENCY ABLATION CATHETER - The present invention provides a bipolar radiofrequency ablation catheter comprising a working catheter and a magnetic catheter. The magnetic catheter comprises a first tube; a magnet; a first electrode; and a first electrode connector, and the working catheter comprises a second tube; a metallic element; a second electrode; and a second electrode connector. According to the present invention, it is possible to create transmural lesions more completely and easily at a thick myocardial region such as left ventricle in which a transmural lesion could not be easily created by using conventional radiofrequency ablation catheters and thus it is expected to increase the treatment efficiency for tachycardia such as ventricular tachycardia and atrial fibrillation. | 04-14-2011 |
20090281834 | SYSTEM AND METHOD FOR MANAGING INFORMATION OF DORMANT PATIENTS - Disclosed herein is a system and method for managing information of dormant patients and, more particularly, to such a system and method in which the information of dormant patients is stored and managed in a separate storage server. | 11-12-2009 |
20090187423 | Method for online management of medical record forms - An object of the present invention is to provide a method for the online management of medical record forms, which can provide web screens through terminals to enable doctors, nurses, pharmacists, or the like to immediately online input and read a variety of information created upon treating and caring for patients in a hospital, and can add, modify, delete or manage various medical record forms provided on the web screens and images inserted into records. | 07-23-2009 |
20080300444 | OPHTHALMIC APPLICATOR FOR TREATMENT OF PTERYGIUM OR GLAUCOMA USING 32P ALONE OR IN COMBINATION WITH 103Pd - Disclosed is an ophthalmic applicator for the treatment of pterygium or or glaucoma using a radioisotope. It comprises a source volume for containing the radioisotope therein; a filter volume for controlling a radiation dose emitted from the radioisotope; and an encapsulation volume for encompassing the source volume and the filter volume, wherein the radioisotope is pure | 12-04-2008 |
20080249804 | Method for Managing Medical Information Online - Disclosed is a method for managing medical information online, in which documents of various formats created by physicians during or after treatment, nursing notes created by nurses during or after nursing service, and other various notes or reports created by clinical laboratory staff during or after physical examinations performed on the patients are presented through a network and a variety of information input through the network is comprehensively managed to be later given users having access rights to the information, thereby enabling the users to share the variety of information. | 10-09-2008 |