SARTORIUS STEDIM BIOTECH GMBH Patent applications |
Patent application number | Title | Published |
20160040109 | BIOREACTOR CONTAINER AND INTEGRITY CHECK METHOD FOR BIOREACTOR CONTAINERS - A bioreactor container comprising has an at least locally flexible wall and at least one container opening. The wall of the bioreactor container has a fluid-tight inner sheet, and an at least locally fluid-permeable or structured outer sheet. A method for testing the integrity of the bioreactor container also is provided. | 02-11-2016 |
20150273416 | STIRRER INSTALLATION AID AND METHOD FOR INSTALLING A STIRRER ELEMENT IN A BIOREACTOR - A bioreactor has a stirrer shaft that is driveable by a drive and on which a stirrer element is positioned. The position of the stirrer element is determined by a stirrer installation aid. The stirrer installation aid has a free end with an abutment surface on which the free end of the stirrer element abuts. The stirrer installation aid is designed as a sleeve that comprises a slot extending between the axial ends of the sleeve. The slot is delimited by opposite flanks of a wall, and the sleeve is placed on the stirrer shaft. The stirrer installation aid can be pulled off laterally from the stirrer shaft. A method for installing the stirrer element on the stirrer shaft arranged in the bioreactor also is provided. | 10-01-2015 |
20150203898 | Method For Differentiating Between Living And Dead Cells - The present invention relates to a method for quantitatively determining living and dead cells in a biological sample. The method according to the present invention is based on the determination of the amount of DNA in the sample with the aid of a DNA amplification reaction which does not impair the membrane integrity of living cells. | 07-23-2015 |
20150108050 | CAPSULE BODY ATTACHMENT - A filter housing comprising an accommodation space for accommodating a filter is disclosed, wherein the filter housing further comprises at least one connector-like coupling element configured to indirectly or directly mate with at least one mating coupling element of a mating filter housing; and wherein the coupling element is integrally formed on a portion of the filter housing. | 04-23-2015 |
20150007721 | Hydrophobic or Oleophobic Microporous Polymer Membrane with Structurally Induced Beading Effect - The present invention relates to a hydrophobic or oleophobic microporous polymer membrane having a structurally induced drip-off effect, to methods for producing the membrane according to the invention, to the use of the membrane in the sterile filtration of gaseous fluids, and to the use of the membrane as a liquid barrier in liquid-containing systems to be vented. | 01-08-2015 |
20140298893 | METHOD FOR TESTING THE INTEGRITY OF A HYDROPHOBIC POROUS DIAPHRAGM FILTER - A method for testing integrity of a hydrophobic, porous diaphragm filter ( | 10-09-2014 |
20140193897 | BIOREACTOR CONTAINER AND INTEGRITY CHECK METHOD FOR BIOREACTOR CONTAINERS - A bioreactor container comprising has an at least locally flexible wall and at least one container opening. The wall of the bioreactor container has a fluid-tight inner sheet, and an at least locally fluid-permeable or structured outer sheet. A method for testing the integrity of the bioreactor container also is provided. | 07-10-2014 |
20140165707 | TEST METHOD AND APPARATUS FOR BIOREACTOR CONTAINERS AND USE - A method for testing the integrity of a bioreactor container includes providing a bioreactor container having a fluid-tight, at least locally flexible wall and having at least one container opening and providing a test apparatus having a bioreactor container compartment and a fluid-permeable and/or structured reception sheet arranged replaceably on the bioreactor container compartment. The method continues by arranging the bioreactor container in the bioreactor container compartment so that the bioreactor container wall contacts the reception sheet in the bioreactor container compartment, connecting the container opening of the bioreactor container to a fluid source filling the bioreactor container with a fluid from the fluid source to generate a predetermined positive pressure Pi in the bioreactor container at a first time Ti and determining whether the bioreactor container is sufficiently leaktight. | 06-19-2014 |
20140116941 | METHOD FOR REMOVING BIOPOLYMER AGGREGATES AND VIRUSES FROM A FLUID - The present invention relates to a method for removing biopolymer aggregates and viruses from a fluid. In a first step, the biopolymer aggregates are selectively removed by filtration through a porous, polyamide-comprising shaped body having a native surface. In a second step, the biopolymer aggregate-free fluid is filtered through at least one suitable virus-retentive membrane. | 05-01-2014 |
20140116115 | METHOD AND DEVICE FOR INSPECTING FLEXIBLE CONTAINER - A method for testing a flexible container includes arranging the flexible container on a winding core that can be rotated about a winding axis W and forms an internal support. The method continues by winding the flexible container around the winding axis W arranging an external support around the wound container and connecting at least one container opening of the container to a fluid source. The method proceeds by filling the container with a fluid from the fluid source to generate a predetermined positive pressure P1 in the flexible container at a first time T | 05-01-2014 |
20140080222 | FLUORESCENT DYE FOR PH SENSOR - The present invention relates to a new type of fluorescent with the following formula (I), its preparation process, and also an optical pH sensor which comprises this fluorescent dye immobilized on an analyte-permeable carrier. | 03-20-2014 |
20140071453 | TRANSFLEXION PROBE AND TRANSFLECTIVE SENSOR - The invention comprises a transflexion probe for carrying out a transflexion measurement on a liquid located in a vessel, comprising a probe shaft ( | 03-13-2014 |
20140054186 | DISPOSABLE SENSOR HEAD AND DISPOSABLE CONTAINER - A disposable sensor head for an optical sensor has a central body ( | 02-27-2014 |
20130313184 | FILTRATION CONTAINER - A filtration container for concentration of macromolecules is insertable into a filtrate recovery tube ( | 11-28-2013 |
20130264252 | FILTER - A filter for the filtration of media, having a pleated, cylindrical filter element, which is located between a perforated, cylindrical backflow preventer and a perforated, cylindrical core, the filter element being arranged in pleated folds, a plurality of folds having a first fold height which is greater than the difference between the radius of the backflow preventer and the radius of the core and which, each being inclined in relation to a radial line by an angle of inclination, are directed away from the outer surface of the core, a plurality of folds being provided having at least one second shorter fold height, and the folds of the second shorter fold height being arranged adjacent, radially at the outside, to the backflow preventer and alternatingly adjacent to the folds of the first fold height. | 10-10-2013 |
20130175716 | AERATION DEVICE FOR BIOREACTORS - Aeration device for bioreactors with an aeration element with gas outlet openings arranged in a housing, the aeration element taking the form of a microsparger, the gas outlet openings of which are in each case spaced apart from one another and have a size of between 100 μm and 200 μm. At least one second aeration element with gas outlet openings of a second size is preferably provided, the aeration elements being formed by a common housing with separate aeration channels. | 07-11-2013 |
20130175275 | CLOSURE FOR A NUTRIENT MEDIUM CONTAINER - The invention relates to closure, in particular for a nutrient medium container, wherein a lower part can be covered by an upper part, wherein the lower part and the upper part can be locked against each other by means of at least one locking receptacle and at least one locking part by rotating the lower part and the upper part about a longitudinal axis, and wherein the locking receptacle has a receptacle groove that is covered by a shoulder and that extends perpendicularly to the longitudinal axis, in which receptacle groove the locking part engages, wherein the shoulder has at least one ramp surface extending at an angle from the longitudinal axis on the outer face of the shoulder facing away from the receptacle groove. | 07-11-2013 |
20130164821 | METHOD FOR SEPARATING VIRUSES FROM A CONTAMINANT-CONTAINING LIQUID - The present invention relates to a method for separating viruses from a contaminant-containing liquid medium using two adsorbents having cationic groups, wherein the viruses are adsorbed to the first adsorbent and subsequently eluted and wherein the contaminants present in the resulting eluate are subsequently adsorbed to the second adsorbent. The yield and purity of the viruses obtained as per the method according to the invention is increased by the addition of multivalent anions during the adsorption of the contaminants to the second adsorbent. | 06-27-2013 |
20130139685 | RADIATION-RESISTANT MICROPOROUS MEMBRANE HAVING A HYDROPHOBICITY GRADIENT - The present invention relates to a radiation-resistant microporous membrane having a hydrophobicity gradient, to a method for the preparation thereof, and to the use of the membrane in the sterilizing filtration of gaseous fluids or as a liquid barrier in liquid-containing systems to be vented. | 06-06-2013 |
20130118347 | DEVICE AND METHOD FOR DEGASSING AQUEOUS MEDIA - A device for degassing aqueous media has a first container containing medium to be degassed. A first line connects the first container to a degassing module and a second line connects the degassing module to a second container for receiving the degassed medium. A first non-return valve in the first line prevents backflow from the degassing module to the first container. A hydrophilic membrane in the second line prevents the passage of gas, and a branch between the degassing module and the hydrophilic membrane has a hydrophobic degassing filter for letting out gas. A third line is connected to the first line between the first container and the first non-return valve and to the second line between the second container and the hydrophilic membrane. A second non-return valve in the third line between the first non-return valve and the hydrophilic membrane prevents a flow towards the second container. | 05-16-2013 |
20130089890 | APPARATUS AND METHOD FOR ANALYZING A CONTAMINATED SURFACE - An apparatus ( | 04-11-2013 |
20130078147 | LIQUID-TRANSPORT AND ANALYTICAL TEST DEVICE - A liquid-transport device has a liquid-tight support ( | 03-28-2013 |
20130068673 | FILTER ELEMENT ATTACHMENT, FILTER CARTRIDGE, AND FILTER SYSTEM - A filter element attachment is provided and is attachable to a filter element. The filter element attachment includes a housing for receiving at least a part of the filter element; at least one display configured to display information associated with the filter element. The filter element attachment may be associated with a corresponding filter cartridge and a filter system. | 03-21-2013 |
20130040372 | BIOREACTOR ARRANGEMENT, SHAKING DEVICE AND METHOD FOR IRRADIATING A MEDIUM IN A BIOREACTOR - A bioreactor arrangement has a bioreactor and an illuminating body for illuminating a medium in a reactor interior. The illuminating body has at least one emission surface via which light, reflected by at least one end surface into the reactor interior, is emitted. The bioreactor is formed as a container having a transparent wall. The illuminating body is outside the reactor interior, next to at least one subregion of the transparent wall. The illuminating body forms a support surface for the bioreactor with its emission surface. A shaking device has a reactor holder that can be in oscillated, for a bioreactor with a transparent wall. The reactor holder has a two-dimensional illuminating body, the emission surface of which forms a support surface for the bioreactor, via which light can be reflected into the reactor interior of the bioreactor. | 02-14-2013 |
20130039810 | BIOREACTOR VESSEL HAVING AN OPTICAL FOAM SENSOR - A bioreactor vessel has an optical foam sensor ( | 02-14-2013 |
20130038633 | ASSEMBLING METHOD, OPERATING METHOD, AUGMENTED REALITY SYSTEM AND COMPUTER PROGRAM PRODUCT - An assembling method for assembling a measurement or production set-up includes providing an augmented reality system with a processing device, an output device and a sensing device. The sensing device captures sensing data belonging to a working space. The method then includes providing first and second set-up components having first and second markers at the working space where the second set-up component is connectable to the first set-up component. The method captures the first and second markers by the sensing device and identifies the first and second marker. The processing device retrieves respective digital information assigned to the identified first and second markers from a database and makes a decision on the compatibility of the first set-up component with the second set-up component based on the retrieved digital information. An augmented representation of at least part of the captured sensing data and the decision on the compatibility is output. | 02-14-2013 |
20120329163 | MULTI-WELL PLATE WITH FILTER MEDIUM, AND USE THEREOF - A multi-well plate ( | 12-27-2012 |
20120313267 | AERATION DEVICE FOR BIOREACTORS - Aeration device for bioreactors with a first aeration element with gas outlet openings of a first size and with at least one second aeration element with gas outlet openings of a second size, the aeration elements being formed by a common housing with separate aeration channels. | 12-13-2012 |
20120298891 | TUBE CONSTRICTION VALVE - A tube constriction valve has a valve body ( | 11-29-2012 |
20120276652 | METHOD FOR QUALIFYING A NON-PARTICULATE ION-EXCHANGER ADSORBER - The present invention relates to a method for the validation of a non-particulate ion exchange adsorber and a kit for the validation of a non-particulate ion exchange adsorber. | 11-01-2012 |
20120267518 | SENSOR PROTECTOR - A sensor protector is intended to reduce the sensitivity of the optical sensor ( | 10-25-2012 |
20120264221 | METHOD FOR QUALIFYING A NON-PARTICULATE ADSORBENT BY MEANS OF A SECONDARY REACTION - The present invention relates to a method for the validation of a non-particulate adsorbent by secondary reaction and a kit for the validation of a non-particulate adsorbent by secondary reaction. | 10-18-2012 |
20120248022 | DEVICE AND METHOD FOR TREATING A FILTRATION MEDIUM - A device for processing a porous filtration medium has a holding part that can be mounted on a lower part with the porous filtration medium. An outer wall of the holding part can be positioned outside a surface, of the filtration medium, and a fixing edge arranged in the holding part can be positioned on an edge of the filtration medium. The holding part has a filtration support which, on its side facing away from the filtration medium, is connected to an outlet for reverse flushing. | 10-04-2012 |
20120132813 | OPTICAL SENSOR COMPRISING A LAYER SOLUBLE IN THE MEDIUM TO BE MEASURED AND DEVICE COMPRISING IT, AND PROCESS FOR THEIR PRODUCTION - An optical is provided with reduced sensitivity to radiation, more particularly gamma radiation. The optical sensor is suitable for determining at least one parameter in a medium and includes a matrix containing a fluorescent dye. The matrix is supported by a transparent support. On the side facing the medium, the matrix has a layer soluble in the medium, which layer provides protection against radiation or damaging radiation products. The optical sensor is suitable for implementation in containers and laboratory products, such as disposable bioreactors for example, which are sterilized using gamma radiation. | 05-31-2012 |
20120103579 | PLATE HEAT EXCHANGER - The invention relates to a plate heat exchanger comprising a plurality of plates having flow channels, wherein a first plate has a front side having at least one flow channel for a first fluid and a second plate has a front side having at least one flow channel for a second fluid, and wherein the plates have through openings via which the flow channels for the same fluid are respectively connected to one another, wherein a front plate, which is placed in front of the front side of the first plate, has ports for the first fluid and for the second fluid, wherein an end plate forms the end of the aligned plates, wherein the plates and ports are formed from plastic, and wherein the plates are bonded or welded tightly together. | 05-03-2012 |
20120100605 | DEVICE FOR CULTIVATING CELLS AND/OR MICROORGANISMS - A reactor is designed as a disposable element, a container receives the reactor, and a device comprises a reactor. A drive unit of the device generates a rotating-oscillating motion of the reactor, and the device is utilized for cultivating cells and/or microorganisms. | 04-26-2012 |
20120097880 | Diaphragm Valve - Diaphragm valve having a valve body with an inlet and an outlet, a sealing membrane, and a connecting piece connecting the sealing membrane to a pressure piece of a drive. The valve body, the sealing membrane and the connecting piece are rigidly connected together to form an interchangeable, sealed valve body unit that can be connected to the drive. The connecting piece is molded on the sealing membrane, and the valve body and the sealing membrane are welded ultrasonically to one another. | 04-26-2012 |
20120097557 | CONTAINER HAVING A SENSOR ADAPTER - A container having a sensor adapter for receiving a sensor arrangement for measuring at least one parameter of media contained in a container interior, wherein the sensor adapter is arranged on the wall to the container interior and has an externally accessible receiving opening in a receiving channel, which is bounded toward the container interior, for adapting the sensor arrangement, wherein toward the container interior the receiving channel in the sensor adapter has at least one boundary surface which is formed by a membrane and via which the medium or media to be measured can be supplied to the sensor arrangement. | 04-26-2012 |
20120091326 | SENSOR DEVICE, COMPRISING AN OPTICAL SENSOR, A CONTAINER AND A COMPARTMENTALIZATION MEANS - A sensor device has an optical sensor ( | 04-19-2012 |
20120077994 | METHOD OF OBTAINING SECONDARY PLANT CONSTITUENTS - The present invention relates to a method of isolating phenolic secondary plant constituents from plant material using a microporous membrane which displays affinity ligands for the phenolic secondary plant constituents. | 03-29-2012 |
20120074068 | POLYSACCHARIDE MATRIX HAVING A GRAFTED POLYMER, METHOD FOR PRODUCING THE SAME AND USE THEREOF - A porous, non-particulate, convectively permeable polysaccharide matrix has a surface on which there is fixed a grafted-on polymer derived from at least one ethylenic monomer compound having functional groups, wherein the polysaccharide matrix is prepared by grafting a porous, non-particulate, convectively permeable polysaccharide starting matrix with the at least one ethylenic monomer compound in the presence of an organic acid having at least one carboxylic acid group and/or at least one acidic XH group, where X=—O, —S, or —N, and of a transition metal or lanthanide compound. The polysaccharide matrix has a high protein binding capacity. A process for preparing the polysaccharide matrix and a method for using the polysaccharide matrix for material separation also are provided. | 03-29-2012 |
20120059603 | FILTER DEVICE TEST APPARATUS, FILTER INTEGRITY TESTING METHOD AND COMPUTER PROGRAM PRODUCT - An apparatus automatically carries out an integrity test on a filter device having a fluid inlet, a fluid outlet and a venting port. The apparatus includes a filter integrity testing device having a pressure sensor and/or a flowmeter. An inlet connector is connectable to the fluid inlet, is connected via a wetting liquid supply valve to a wetting liquid supply, and is connected via a drainage valve to a first drain. An outlet connector is connectable to the fluid outlet and via an outlet valve to the first or a second drain. A venting port connector is connectable to the venting port and via a measurement valve to the pressure sensor and/or flowmeter. The venting port connector also is connected via a venting valve to a venting pipe, and via a measurement gas valve to a measurement gas source. The valves are controlled by the filter integrity testing device. | 03-08-2012 |
20120015394 | Transfer Unit and Method for Receiving a Medium From a Processing Device - The invention relates to a transfer unit for receiving in particular a porous disc-shaped medium from a first treatment device, having an upper part, wherein the upper part comprises a fixing edge that can be connected to an edge of the medium for removing the medium from the first treatment device, wherein the upper part comprises an opening closed by a removable cover, by means of which successive treatments in a further treatment device can be performed. The invention further relates to a method wherein an upper part of a transfer unit is placed on a disc-shaped medium disposed in a first lower part of a first treatment device and exposed to the liquid sample and is connected to an edge of the medium, wherein the upper part is lifted off from the first lower part with the disc-shaped medium connected thereto, and is placed on a further lower part of a corresponding treatment device, and is further processed through an opening in the upper part. | 01-19-2012 |
20110272357 | APPARATUS AND METHOD FOR MATERIAL SEPARATION - An apparatus for separating or isolating substances in or from a mixture has at least one diffusion-based chromatography matrix and at least one convection-based chromatography matrix. | 11-10-2011 |
20110266449 | OPTICAL SENSOR AND DEVICE THEREWITH, AND METHOD FOR THE PRODUCTION THEREOF - An optical sensor is provided with reduced sensitivity toward external light influences, fluorophores, and radiation, more particularly gamma radiation. The sensor is suitable for determining at least one parameter in a medium. The sensor has a matrix that contains a fluorescent dye. The matrix is supported by a transparent substrate and has a precious metal layer on the side facing the medium. The precious metal layer provides protection against photobleaching and radiation. The optical sensor is suitable for implementation in containers and laboratory products that are sterilized by gamma radiation, such as disposable bioreactors. | 11-03-2011 |
20110265820 | CLEANING PROCESS FOR A TEST DEVICE, COMPUTER PROGRAM PRODUCT FOR PERFORMING SUCH A PROCESS, AND TEST DEVICE - A cleaning process is provided for a test apparatus that has a switch, external connections and internal volumes that can come into contact with a fluid from a filter to be tested or a container to be tested. The cleaning process includes selecting one or more internal volumes to be cleaned, cleaning the selected internal volumes with a cleaning fluid by a corresponding switching of the switch, at least partially draining the cleaning fluid left in the selected internal volumes after cleaning, and flushing the selected internal volumes with a flushing fluid different from the cleaning fluid. Also provided are a computer program product for performing the cleaning process, a cleaning apparatus, and a test apparatus for testing filters and containers. | 11-03-2011 |
20110244215 | ELECTRON BEAM INDUCED MODIFICATION OF MEMBRANES BY POLYMERS - A method and an apparatus are provided for carrying out integrity tests of at least one filter element, arranged within a filter housing, with porous filter materials. Sensors are provided for measuring the sound generated by a test fluid when it flows through the filter element. The method includes applying a test fluid to a first side of the filter materials of the filter element while maintaining a constant fluid pressure, measuring the body-borne sound and/or the vibrations caused by test fluid flowing through the filter materials by sensors, and comparing the body-borne sound and/or the vibrations with the body-borne sound and/or the vibrations of an integral, identical filter element, measured under identical conditions. | 10-06-2011 |
20110233210 | CLOSURE FOR A CONTAINER - A closure for a container has an upper part ( | 09-29-2011 |
20110229963 | STIRRER FOR A BIOREACTOR - A stirrer for a bioreactor has first and second opposed mountings fastened to the inner surfaces of opposite walls of the bioreactor and disposed along a common rotational axis. A first arm has an end connected to the first mounting for rotation about the rotational axis and for pivoting about a first pivot axis that is transverse to the rotational axis. A second arm has an end connected to the second mounting for rotation about the rotational axis and for pivoting about a second pivot axis that is transverse to the rotational axis. Ends of the arms are coupled for pivoting about at least one additional pivot axis that is transverse to the rotational axis. | 09-22-2011 |
20110214485 | METHOD AND APPARATUS FOR CARRYING OUT INTEGRITY TESTS - A method and an apparatus are provided for carrying out integrity tests of at least one filter element, arranged within a filter housing, with porous filter materials. Sensors are provided for measuring the sound generated by a test fluid when it flows through the filter element. The method includes applying a test fluid to a first side of the filter materials of the filter element while maintaining a constant fluid pressure, measuring the body-borne sound and/or the vibrations caused by test fluid flowing through the filter materials by sensors, and comparing the body-borne sound and/or the vibrations with the body-borne sound and/or the vibrations of an integral, identical filter element, measured under identical conditions. | 09-08-2011 |
20110198255 | CONTAINER HAVING A COMPUTER PRODUCT - A storage and/or reaction container system for fluids, includes a container and an electronic documentation device connected to the container. The documentation device further includes a timing device for capturing a point in time, at least one sensor, at least one input device for capturing inputs, and a storage device to store for readout at least one measured value captured by the at least one sensor device and/or an input captured by the at least one input device. The at least one measured value and/or the at least one input is associated by the timing device with the point in time of the capture. | 08-18-2011 |
20110163029 | METHOD FOR SUBSTANCE SEPARATION USING A CELLULOSE HYDRATE MEMBRANE IN SIZE EXCLUSION CHROMATOGRAPHY - There is proposed a separation method for mixtures of materials, using a cellulose hydrate membrane having a porous double structure which consists of micropores having a diameter in the range from >100 nm to 20 μm and ultrapores which have a diameter of <100 nm and which are not accessible to Blue Dextran having an average molecular weight Mw of 2 000 000, wherein the fraction of the volume of the ultrapores is more than 15% of the entire pore volume accessible to water, and wherein, in a preferred embodiment, sulfonic acid ligands are bonded to the membrane. | 07-07-2011 |
20110148597 | Dosing System and Method for the Dosing of a Medium - A dosing system and a method for dosing a medium, having a dosing control unit ( | 06-23-2011 |
20110147292 | CELLULOSE HYDRATE MEMBRANE, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF - There is provided a cellulose hydrate membrane having a porous double structure which consists of micropores having a diameter in the range from >100 nm to 20 μm and ultrapores which have a diameter of <100 nm and which are not accessible to Blue Dextran having an average molecular weight Mw of 2 000 000, wherein the fraction of the volume of the ultrapores is more than 15% of the entire pore volume accessible to water. In addition, a method for producing the membrane, its use as an adsorption membrane, and an apparatus for membrane chromatography are specified. | 06-23-2011 |
20110120947 | HYDROPHOBIC CELLULOSE MEMBRANE, METHOD FOR THE PRODUCTION THEREOF, AND USE OF SAME IN HYDROPHOBIC INTERACTION CHROMATOGRAPHY - There is provided a crosslinked cellulose hydrate membrane having a porous double structure which consists of micropores having a diameter in the range from >100 nm to 20 μm and ultrapores which have a diameter of <100 nm and which are not accessible to Blue Dextran having an average molecular weight Mw of 2 000 000, wherein the fraction of the volume of the ultrapores is more than 15% of the entire pore volume accessible to water, and wherein hydrophobic ligands, selected from C | 05-26-2011 |
20110100892 | ADAPTER FOR FASTENING A FILTER ELEMENT - An adapter is provided for fastening a filter element in a cylindrical receiving opening of a bottom part of a lower piece of a filter housing. The adapter has at least one seal arranged in a peripheral groove on the circumference of the adapter to permit fluid-tight separation of a non-filtrate chamber, which surrounds the external jacket of the filter and from which medium to be filtered can be delivered to the filter, from a filtrate chamber into which the filtrate can be introduced from the filter. The seal is connected by injection molding to a base surface of the peripheral groove and is at a distance from at least one side wall delimiting the base surface of the groove. | 05-05-2011 |
20110076759 | BIOREACTOR WITH CONDENSER - Bioreactor with a vessel having at least one gas dissipation duct for gas discharge, the orifice of the gas dissipation duct being connected to a hydrophobic sterile filter and to a condenser arranged between them and having condensation surfaces, a turbulence generator for generating a turbulent flow is arranged in the gas dissipation duct in the region of the condenser. | 03-31-2011 |
20110058448 | MIXING SYSTEM - A mixing system has a single-use container ( | 03-10-2011 |
20110058447 | MIXING SYSTEM - A mixing system has a container with flexible walls ( | 03-10-2011 |
20110038222 | MIXING VESSEL - A mixing vessel includes a flexible container, elements for mixing its contents, aeration elements, a drain/lower bearing port having a rigid flange provided with a drain passage, attached in a tight manner to the lower portion of the container wall, supporting a lower bearing that is adjacent to the drain passage. The vessel includes an extended element for dispensing aeration gas and is spaced essentially radially from the drain/bearing port; at least one tubular element for dispensing aeration gas extends from the extended dispensing element, in the inside space, along the inside surface of the lower portion and the side portion of the wall of the container and extends on the outside of the container from the upper portion; at least one mixing element is spaced essentially from the lower portion of the container wall, from the lower bearing, and from at least one extended element for dispensing aeration gas. | 02-17-2011 |
20110026360 | FLEXIBLE POUCH WITH A MIXING APPARATUS - A flexible pouch has a mixing apparatus, the mixer shaft of which is adjustable in length for use as a bioreactor for culturing microorganisms and cells. | 02-03-2011 |
20110020922 | BIOREACTOR - The invention relates to a bioreactor for cultivating cells having a filter bag for separating culture fluid and cells, the filter medium of the filter bag having a degree of swelling of less than 1%. The bioreactor according to the invention is characterized by a high durability of the filter bag thereof. | 01-27-2011 |
20110014075 | HOSE SYSTEM - A hose system has a pump hose with a hose portion insertable into a pump head of a hose pump. The hose portion has at least a first stop element fixing the hose portion in the feed direction. The first stop element can subsequently be connected immovably to the pump hose at a predefinable position of the pump hose. Thus, the pump hose can be used more universally and can be adapted to different pump heads. | 01-20-2011 |
20110013474 | DISPOSABLE MIXING VESSEL - A disposable mixing vessel comprising a flexible container, a centrally disposed shaft having first and second ends with one or more impellers thereon and a magnetic element associated with a first shaft end, a first flange adapted to rotatably engage the first shaft end and a second flange adapted to rotatably engage the second shaft end. | 01-20-2011 |
20110013473 | METHOD OF MIXING - A method of mixing including providing a flexible container which comprises at least two components, assembling the components from outside the flexible container to form a centrally disposed magnetic driven shaft with at least one impeller, whereby the integrity of the flexible container is maintained, filling the flexible container having the centrally disposed magnetic driven shaft with one or more ingredients of the contents to be mixed; engaging a magnetic element of the centrally disposed magnetic driven shaft with an external magnetic drive element; analyzing the contents of the flexible container using at least one sensor or a sampling line on the flexible container; and draining the contents of the flexible container through a drain port at the bottom of the flexible container. | 01-20-2011 |
20110011176 | CONNECTING ELEMENT FOR CONNECTING A MEASUREMENT RECORDER TO A SEALED FLUID SYSTEM - The invention relates to improving a system element for releasably sealed connecting of a measurement recorder to a fluid system, having a measurement chamber ( | 01-20-2011 |
20110005984 | PRESTERILIZABLE FILTRATION SYSTEM TO BE DISPOSED OF AFTER A SINGLE USE - A presterilizable filtration system is provided and is to be disposed of after a single use. The system has a recirculation tank and a filtration module that are connected to each other in a circuit via a hose system that can be regulated by at least one valve. The valve has a disposable separate valve part that can be integrated in the hose system and a reusable actuator. | 01-13-2011 |
20110003374 | BIOREACTOR - A bioreactor ( | 01-06-2011 |
20100330691 | Process for Producing Surface Enhanced Membrane - A membrane having a refined surface as well as to a process and an apparatus for producing such a membrane, and which is useful, in particular, for rapid diagnostic tests for identifying specific analytes in liquid media. | 12-30-2010 |
20100330663 | INCUBATOR COMPRISING A SHAKING DEVICE - An incubator ( | 12-30-2010 |
20100301042 | CONTAINER WITH FLEXIBLE WALLS - A container arrangement has a container with a flexible wall. The container may be a disposable container and is insertable into a supporting container so that an inner supporting surface of the supporting container surrounds and supports a lateral wall of the container. At least one baffle that has a temperature-regulating system is disposed in proximity to the lateral wall of the container and/or the supporting surface of the supporting container. | 12-02-2010 |
20100282665 | FILTER CAPSULE - A filter capsule has a filter housing which, on at least one end face, has an end cap with an air release valve. A protective wall is formed on the end cap at a distance from the air release valve and protrudes beyond the air release valve. | 11-11-2010 |
20100260010 | CONTAINER WITH FLEXIBLE WALLS - A container with a flexible container wall, in particular a disposable bioreactor, with a container interior in which a a mixer is arranged at one end of a mixer shaft which is passed through the container wall and is drivable from the outside, wherein the mixer shaft and/or mixer is/are designed such that it/they are foldable and such that it/they can be stabilized from the outside. | 10-14-2010 |
20100175774 | DEVICE AND METHOD FOR METERING MEDIA - The invention relates to a device ( | 07-15-2010 |
20100170400 | Waste gas system for bioreactors - The invention relates to a waste gas system for bioreactors having a hydrophobic sterile filter, arranged at the end, and a heat exchanger which protects the sterile filter against blocking by liquid media. The gas outflow duct for discharging waste gas from a bioreactor vessel is divided in a cooling zone of the heat exchanger into a multiplicity of subducts and is extended in a heating zone of the heat exchanger to a calming zone. Due to the multiplicity of subducts, a considerably larger surface area for the removal of heat from the waste gas is available, with the result that in the case of laminar flow of the waste gas through the subducts a high effectiveness of the separation of liquids from the waste gas can be achieved. In the heating zone, the waste gas can heat up again due to the reduced flow rate until it reaches the hydrophobic sterile filter by way of taking up heat from the surroundings to a such a degree that the relative vapor contents are below 100% and separation of liquids from residual vapors at or in the hydrophobic sterile filter is precluded. | 07-08-2010 |
20100086959 | FILTRATION UNIT AND METHOD FOR THE MICROBIOLOGICAL ANALYSIS OF LIQUID SAMPLES - The invention relates to a filtration unit, comprising a membrane filter that can be disposed on a filter support of a bottom part and an attachment that can be placed on the bottom part, wherein the membrane filter has a reinforcing edge, and wherein the membrane filter can be clamped to a clamping part of a cover of a culture medium unit for removal purposes and introduced into the culture media unit. The invention further relates to a method for the microbiological analysis of liquid samples following a filtration process, wherein after removing an attachment a membrane filter is lifted off a filter support for pouring in the liquid sample and set down on a surface of a culture medium disposed in the bottom part of a culture medium unit, and the bottom part is covered by a cover. The cover is placed on the membrane resting on the filter support such that a clamping part present on the filter support clamps to a reinforcing edge of the membrane. The cover is lifted off the filter support together with the membrane and placed on the bowl-shaped bottom part such that the bottom of the membrane facing away from the cover rests on the top of the nutrient medium facing the cover. | 04-08-2010 |
20100072125 | FILTER CARTRIDGE UNIT WITH ADHESIVE INTERCONNECTING FILTER CARTRIDGE AND END PLATES - A filter cartridge unit including a first end plate, at least one second end plate, and a filter cartridge that is arranged between the end plates. The filter cartridge is connected, in a form-fitting and fluid-tight manner, to its adjacent end plates in a circumferential subarea of contact surfaces thereof using an adhesive. | 03-25-2010 |
20100059403 | PROTECTED FILTER UNITS FOR SAFETY FILTRATION AND METHOD FOR PRODUCTION THEREOF - The invention relates to protected filter units for safety filtration, in which the filter units are at least double-packed with different packaging materials and to a method for producing the protected filter units. In this case, the first packaging material is permeable to gases but impermeable to microorganisms and the at least second packaging material is impermeable to gases. The first packaging material fixes the at least one filter unit, and so no abrasion can take place during transport and handling. The filter units according to the invention are suitable for sterile filtration processes and for filtration processes under clean-room conditions. | 03-11-2010 |
20100035337 | Bioreactor with window - Bioreactor having at least one transparent window ( | 02-11-2010 |
20100028933 | NUTRIENT MEDIUM UNIT AND METHOD FOR HOLDING A FILTER FROM A FILTRATION DEVICE - The invention relates to a nutrient medium unit for holding a filter of a filtration device, comprising a lower part that is filled with the nutrient medium and a lid, the latter having a fixing edge that protrudes into the lower part and that can be connected to an edge of the filter by means of an adhesive bond in order to remove said filter from the filtration device. The invention also relates to a method for the microbiological analysis of liquid samples, according to which a membrane filter is lifted off a filter support and laid on the surface of a nutrient medium that is situated in a lower part of a nutrient medium unit. The lower part is then covered by a lid, the latter being placed on the membrane filter lying on the filter support in such a way that a fixing edge located in the lid is connected to an edge of the filter by means of an adhesive bond. The lid and the attached filter are lifted off the filter support and placed on the dish-shaped lower part of the nutrient medium unit. | 02-04-2010 |
20100014379 | Agitator apparatus with collapsible impeller - An agitator apparatus for a mixing vessel having a rotating member and one or more impellers coupled to the rotating member, at least one of the impellers being collapsible so that the collapsible impeller is movable from a collapsed orientation to a deployed orientation relative to the rotating member. A limiting member may be used to prevent the collapsible impeller from opening beyond its fully deployed orientation. | 01-21-2010 |
20100000348 | Device for fastening a sensor on containers - Device for fastening a sensor on containers with a flexible container wall, in particular mixing bags, comprising a sensor support which is fitted with a sensor, bears against an inner wall of the container wall at least with a rear subsurface averted from the sensor, and is guided with a central piece through an opening in the container wall in which the sensor support is fixed on the container wall by a clamping part which can be connected to the central piece, in which the container wall is clamped between the rear subsurface of the sensor support and on a bearing surface, facing an outer wall of the container, of the clamping part, and in which the rear subsurface bears sealingly against the inner wall of the container wall. The sensor support can also have an electronic or optical transmit unit which is connected to the sensor, in which case the transmit unit communicates in a wireless fashion with a receive unit arranged outside the container. | 01-07-2010 |
20090311775 | Disposable Bioreactor for Culturing Cells in a Nutrient Medium - Disposable bioreactor for culturing cells in a nutrient medium, consisting of a reagent container which is sealable with a lid and which is capable of being subjected to a shaking process in a shaking device, where the reagent container is equipped with at least one web adjacent to the internal wall of the container, the web being arranged running vertically from the bottom upward, preferably in the shape of a helix. | 12-17-2009 |
20090301962 | Filtration housing - A housing ( | 12-10-2009 |
20090275121 | Vibrational Mixer - A vibrational mixer ( | 11-05-2009 |
20090266756 | Filter module and filter unit - Filter module and filter unit with an inlet for medium that is to be filtered, and with an outlet for the permeate, with at least one filter sheet, a first spacer adjacent to the media side and a second spacer adjacent to the permeate side, the spacers being designed with a draining action, and the first spacer being connected to an inlet and the second spacer to an outlet, wherein the at least one filter sheet forms a first filter unit together with the two adjacent spacers, the filter sheet is designed as a single filter or a filter stack, the first spacer is designed to be impermeable to liquid on its outer face directed away from the filter sheet and is sealed off at its boundary to the outlet end, and the second spacer is designed to be impermeable to liquid on its outer face directed away from the filter sheet and is sealed off at its boundary to the inlet end. | 10-29-2009 |
20090147617 | Container and method for the mixing of media - Container and method for the mixing of media, in particular as a disposable container, which has at least one closable opening for the introduction and/or removal of the media and has a first sensor for measurement of at least one parameter of the mixture, in which at least one second sensor for measurement of the same parameter is arranged at a distance from the first sensor. | 06-11-2009 |
20090103772 | Method and Detection Device for the Imaging Detection of a Sample - The invention relates to a device for detecting a sample in a longitudinal sample container ( | 04-23-2009 |
20090075362 | Disposable Bioreactor Comprising a Sensor Arrangement - The invention relates to a disposable bioreactor comprising a reversible, externally attachable sensor arrangement for measuring a physical variable of a contained medium. A sensor adapter ( | 03-19-2009 |
20090050213 | Connector, Connector System and Use Thereof - The invention relates to a connector ( | 02-26-2009 |
20090017282 | Method for Opening the Film Layer of Plastic Foam Strip - The invention relates to a method for opening the film layer of a plastic foam strip, to a plastic foam strip that can be obtained by said method and has an at least partially opened film layer, and to the use thereof, for example, as a filtration membrane, an oil absorber, or a liquid-absorbent packaging material. | 01-15-2009 |
20080305370 | FUEL CELL SYSTEM AND METHOD OF OPERATING A FUEL CELL - The invention provides an improved fuel cell system and a method of operating a fuel cell, which ensure that the fuel cell can be operated at high efficiency without irreversible damage. The fuel cell system according to the invention has at least one fuel cell with a fuel cell stack and with separator plates, which are equipped with inlets and outlets for a heat transfer medium, a thermostat, a heat transfer medium circuit, which has a transport device for the heat transfer medium and includes at least the fuel cell and the thermostat, at least one temperature sensor for the fuel cell and a monitoring and control unit for the temperature of the fuel cell. With the invention it is possible to operate the fuel cell in a range close to the preset optimum operating temperature. | 12-11-2008 |
20080213753 | METHOD FOR THE VERIFICATION OF THE REMOVAL OF VIRUSES TO VALIDATE FILTERS AND FILTERING PROCESSES - Disclosed is a method for verification of the removal of viruses to validate filters, filtering processes, physical and chemical inactivation processes, or adsorptive removal processes in predefined process conditions that are simulated on a small scale. According to said method, viruses are cultured in suitable cell lines in a first step, a virus suspension is obtained after solubilizing cells in a second step, the virus suspension obtained is added in a third step to a protein solution that is to be analyzed, and the virus-containing protein solution is filtered through the filter that is to be validated, and the removal of viruses is then analyzed in a fourth step. The virus suspension is first processed via a membrane adsorber following step two, the viruses being bonded to the membrane adsorber and contaminants being removed with the aid of a detergent buffer solution, while the bonded, purified viruses are eluted from the membrane adsorber area and are added to the protein solution that is to be analyzed as a concentrated virus suspension in step three. | 09-04-2008 |