Rheinische Friedrich-Wilhelms-Universitat Bonn Patent applications |
Patent application number | Title | Published |
20150275217 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM - The present invention relates to new triphosphate-modified oligonucleotides which may act as RIG-I ligands as well as a new method allowing the synthesis and purification in high yield and purity suitable for pharmaceutical applications. | 10-01-2015 |
20150057161 | HIGH-RESOLUTION TRANSCRIPTOME OF HUMAN MACROPHAGES - The invention is based on the finding of specific surface markers for M1-like (classically activated) and M2-like (alternatively activated) macrophages and provides for a method for the identification, characterization and isolation of M1-like and M2-like macrophages based on the abundance of said surface markers and for means for performing such method. | 02-26-2015 |
20140288019 | Phosphorylated A2A Receptor Agonists - A phosphorylated A | 09-25-2014 |
20140066409 | CYCLOHEXANE COMPOUNDS AND THEIR USE AS ANTIBIOTICS - The present invention relates to compounds according to general formula (I), pharmaceutical compositions comprising compounds according to general formula (I) and the use of the compounds for the treatment of a bacterial infection, particularly for use as an antibiotic. | 03-06-2014 |
20130344486 | METHOD OF DIAGNOSING BREAST CARCINOMA - The present invention relates to methods of diagnosing a breast carcinoma, determining the prognosis of a patient diagnosed with breast carcinoma and determining the efficacy of a treatment regimen of breast carcinoma in a patient, using Calponin-h2 and/or CALML 5 as markers. Furthermore, the invention relates to a kit and a marker panel for use in these methods. | 12-26-2013 |
20130338374 | GPR 17 AGONISTS AND SCREENING ASSAY - The present invention is related to a method of determining a test compound's ability to modify the biological activity of a GPR17. Said method comprises, among others, the step of contacting the test compound with a GPR17, or a functional GPR17 fragment in the presence of a suitable amount of a GPR17 agonist of formula I. | 12-19-2013 |
20130158093 | GPR 17 Agonists and Screening Assay - The present invention is related to a method of determining a test compound's ability to modify the biological activity of a GPR17. Said method comprises, among others, the step of contacting the test compound with a GPR17, or a functional GPR17 fragment in the presence of a suitable amount of a GPR17 agonist of formula I. | 06-20-2013 |
20130059899 | METHODS OF IDENTIFYING MODULATORS OF GPR17 - The present invention is related to a method of determining a test compound's ability to modify the biological activity of a GPR17. Said method comprises, among others, the step of contacting the test compound with a GPR17, or a functional GPR17 fragment in the presence of a suitable amount of a GPR17 agonist of formula I. | 03-07-2013 |
20110070421 | NON-WETTABLE SURFACES - An object having a surface that has:
| 03-24-2011 |
20100210654 | NOVEL P2Y12 RECEPTOR ANTAGONISTS - The present invention relates to novel P2Y | 08-19-2010 |
20100204182 | ECTONUCLEOTIDASE INHIBITORS - The present invention provides ectonucleotidase inhibitors represented by the following formula, including ecto-nucleotide triphosphate diphosphohydrolase (NTPDase) inhibitors and ecto-5′-nucleotidase (ecto-5′-NT) inhibitors, namely nucleotide mimetics as selective NTPDase or ecto-5′-NT inhibitors. It also provides methods for preparations of said compounds. Furthermore provided are pharmaceutical and diagnostic compositions comprising said compounds, and the use of said compounds in a medicament for treating diseases associated with ectonucleotidase activity and/or P1 or P2 receptors. | 08-12-2010 |
20100179225 | POI Prevention - A method is provided, comprising administering at least one guanylhydrazone or salt thereof or a combination thereof to a subject to prevent or ameliorate in said subject at least one of postoperative intestinal inflammation, postoperative ileus, ischemia reperfusion injury, or a combination thereof. | 07-15-2010 |
20100048501 | Phosphorylated A2A Receptor Agonists - A phosphorylated A | 02-25-2010 |
20090005338 | Carbonyl-substituted titanocenes - A medicament containing a compound of the following formulas (Ia) and (Ib): | 01-01-2009 |