RADIKAL THERAPEUTICS INC.
|RADIKAL THERAPEUTICS INC. Patent applications|
|Patent application number||Title||Published|
|20130338146||MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF - Multifunctional nitroxide derivatives comprising a potassium channel opener and a reactive oxygen species (ROS) degradation catalyst that can act as an anti-oxidant, as well as pharmaceutical compositions comprising them are provided. The multifunctional compounds and pharmaceutical compositions are useful for treatment of diseases, disorders or conditions associated with oxidative stress or endothelial dysfunction.||12-19-2013|
|20130116284||LIPOIC ACID AND NITROXIDE DERIVATIVES AND USES THEREOF - Provided are bifunctional compounds comprising a poly(ADP-ribose) polymerase (PARP) inhibitor moiety and a reactive oxygen species (ROS) scavenger moiety, more particularly, a lipoic acid or cyclic nitroxide derivative, covalently attached either directly or via a linker, as well as pharmaceutical compositions comprising them. The compounds and pharmaceutical compositions are useful for prevention, treatment, or management of diseases, disorders and conditions associated with elevated PARP activity or expression.||05-09-2013|