20150218586 | MINICIRCLES WITH VIRAL EXPRESSION CASSETTES AND THEIR USE IN THE TRANSFORMATION OF CELLS FOR GENERATING RECOMBINANT VIRUS OR VIRAL GENE VECTORS - The invention relates to a minicircle transfer vector for producing viral vectors comprising a transfer sequence and specific packing signals flanking both sides of the transfer sequence for packaging of the transfer sequence into particles of a viral vector. The invention also relates to minicircle packaging vectors carrying support functions for producing viral vectors. The invention further relates to cells bearing the disclosed minicircles. The invention further relates to methods for producing viral vectors using such minicircles and viral vectors obtained thereby, as well as kits useful in performing the described methods. | 08-06-2015 |