Paul-Ehrlich-Institute of the Federal Republic of Germany
| Paul-Ehrlich-Institute of the Federal Republic of Germany Patent applications | ||
| Patent application number | Title | Published |
|---|---|---|
| 20140065694 | ENHANCED TUMOR THERAPY BY TUMOR STEM CELL TARGETED ONCOLYTIC VIRUSES - The invention relates to recombinant oncolytic viruses that target tumor stem cells and various uses of these recombinant viruses. In particular, an oncolytic virus comprising a recombinant binding domain specific for a tumor stem cell marker is disclosed. Furthermore, the use of such oncolytic viruses for the treatment of cancer is disclosed. | 03-06-2014 |
| 20140018521 | Methods for the identification and repair of amino acid residues destabilizing single-chain variable fragments (scFv) - The invention relates to a method for identifying stabilizing amino acids in single chain antibody fragments. | 01-16-2014 |