OMRIX Biopharmaceuticals Ltd.
|OMRIX Biopharmaceuticals Ltd. Patent applications|
|Patent application number||Title||Published|
|20140188141||Device and Method for the Application of a Curable Fluid Composition to a Portion of a Bodily Organ - Disclosed are devices and methods suitable for application of a curable fluid composition to a bodily organ, such as to a lower portion of a bodily organ. The device comprises a monolithic piece of material having a lower surface, two spaced-apart sides, and two spaced-apart walls connecting the two spaced-apart sides. A receptacle for containing the curable fluid composition is defined by the lower surface, the two sides, and the two walls. At least a portion of the height of the two walls is less than the height of at least a portion of the two sides. The device is deployable underneath the bodily organ such that a lower portion of the bodily organ is supported by at least a portion of each of the two walls.||07-03-2014|
|20140179602||Viral Inactivated Biological Mixture - The invention relates to a viral inactivated biological liquid or dry mixture and to its preparation. Principally, the invention relates, but is not limited, to a mixture derived from a platelet source.||06-26-2014|
|20140088642||DEVICE AND METHOD FOR THE APPLICATION OF A CURABLE FLUID COMPOSITION TO A BODILY ORGAN - The invention relates to a device suitable for application of a curable fluid composition to encircle a bodily organ. The device comprises a monolithic piece of a flexible material having a length dimension with an inner surface and an outer surface, a first end and a second end, a width dimension, and two spaced-apart sides, wherein a portion of the length dimension proximal to the first end is configured to contact a portion of the length dimension proximal to the second end, the inner surface defining a hollow area between the two spaced-apart sides; and at least one inlet providing fluid communication between the outer surface and the inner surface, for introduction of the fluid into the hollow area. The device deployable around the bodily organ such that when the portion of the length dimension proximal to the first end contacts the portion of the length dimension proximal to the second end, an outer surface of the bodily organ and the hollowed area define an enclosed volume encircling the bodily organ, the enclosed volume suitable for containing the fluid therein.||03-27-2014|
|20140056989||VIRAL INACTIVATED PLATELET EXTRACT, USE AND PREPARATION THEREOF - The invention relates to a viral-safe platelet extract, to its preparation and use. The extract comprises a mixture of biologically active platelet derived factors.||02-27-2014|
|20130011388||INTRAVENOUS IMMUNOGLOBULIN COMPOSITION - A concentrated, immunoglobulin composition for treating subjects vaccinated against or infected with a pathogenic microorganism, is made by (a) selecting a population of individuals previously vaccinated against antigens associated with the pathogenic microorganism; (b) identifying very high titre individuals by determining the level of specific antibodies immunoreactive with the pathogenic microorganism in the blood of the individuals; (c) combining blood from the very high titre individuals; and (d) purifying and/or concentrating the product of step (c). A concentrated immunoglobulin composition can include specific antibodies immunoreactive with a pathogenic microorganism, wherein the titre of specific antibodies is at least 5 times higher than the average titre of specific antibodies of a population of individuals previously vaccinated against antigens associated with the pathogenic microorganism. The composition has a relatively high protein concentration and a low percentage of protein aggregates. The pathogenic microorganism is preferably smallpox virus or vaccinia virus.||01-10-2013|
|20130005947||METHOD FOR REMOVING A LYTIC ENZYME FROM A HETEROGENEOUS MIXTURE - The invention relates to purification of an intact, non-degraded macromolecule from a biological mixture comprising the macromolecule in the presence of its lytic enzyme. The method comprises providing the biological mixture as a heterogeneous mixture comprising the lytic enzyme, at least partially, in soluble form and the macromolecule, at least partially, in non-soluble form; batch-wise contacting the heterogeneous mixture with an immobilized inhibitor of the lytic enzyme; increasing the solubility of the macromolecule in the mixture; and removing the immobilized inhibitor from the mixture.||01-03-2013|
|20120305669||DEVICE FOR SPRAYING AND/OR MIXING FLUIDS IN PROXIMITY TO A SURFACE - The invention relates to an applicator tip for spraying and/or mixing at least two fluids that react together, the tip comprising: at least two fluid conduits for carrying the at least two fluids, each conduit having at least one outlet opening, the openings are positioned substantially on a same plane; at least two gas conduits for carrying a gas volume, each gas conduit comprises a proximal gas tube and a distal gas tube, each distal gas tube is bent as compared to the position of the proximal gas tube, and each distal gas tube has one gas opening positioned distal from the plane of the outlet openings; and a housing for accommodating the at least two fluid conduits and the at least two gas conduits. The device allows efficient spraying in close proximity to a surface.||12-06-2012|
|20120294847||IMMUNOGLOBULIN REDUCED IN THROMBOGENIC AGENTS AND PREPARATION THEREOF - The invention relates to an immunoglobulin composition reduced in thrombogenic agents and to methods for its preparation. One method comprises subjecting an immunoglobulin containing solution to a negative cation exchanger chromatography at a pH in the range of higher than 3.8 to equal to or lower than 5.3. The solution can also be subjected to a negative anion exchanger chromatography at a pH in the range of 7 to 8.2.||11-22-2012|
|20100143378||Subcutaneous Administration of Anti-Hepatitis B Antibodies - The present application relates to an immunoglobulin preparation comprising anti-hepatitis B antibodies for subcutaneous administration and to uses thereof, including methods for treating, preventing and/or reducing a disease, disorder or condition associated with hepatitis B virus.||06-10-2010|
|20100068196||METHOD OF MICRONIZATION - A method for micronization of a dispersion of particles including a protein having a predetermined level of biological activity, is provided. The method includes introducing the dispersion into a vortex chamber milling apparatus under milling conditions which result in a protein powder having a particle size distribution of 5 to 100 μm and/or exhibiting a 30 to 400 fold size reduction of the protein particle dispersion from its original size, and retaining at least 80% of the predetermined level of biological activity of the protein. The milling conditions include one or more parameters selected from the following: input pressure between 1 and 7 Bars; injector pressure between 0.2 and 5 Bars; loading rate between 0.1 and 5 kg/hour; and gas flow between 30 and 100 m||03-18-2010|
Patent applications by OMRIX Biopharmaceuticals Ltd.