Kennedy Krieger Institute, Inc.
Baltimore, MD US
|Kennedy Krieger Institute, Inc. Patent applications|
|Patent application number||Title||Published|
|20160106871||NOVEL PEPTIDE HYDROGELS GENERATING CHEMICAL EXCHANGE SATURATION TRANSFER MRI CONTRAST AND USES THEREOF - The present invention provides novel hydrogels through peptides, which are designed to self-assemble and produce magnetic resonance (MR) contrast through chemical exchange saturation transfer (CEST). The location and integrity of these gels could consequently be tracked using MR imaging. The self-assembly of the peptides into hydrogels can be brought about by a change in pH, ionic strength, temperature, and concentration of ions.||04-21-2016|
|20150110751||STEM CELLS AS AN INDIVIDUALIZED MATERNAL THERAPY FOR PREVENTION OF PREMATURITY - The present invention relates to the field of premature birth. More specifically, the present invention provides methods and compositions useful for preventing premature birth. In one embodiment, a method for preventing preterm birth in a patient comprises the step of administering to the patient an effective amount of autologous mesenchymal stem cells (MSCs) during the first or second trimester.||04-23-2015|
|20140336138||COMPOSITIONS AND METHODS FOR SCREENING AND TREATMENT OF STURGE-WEBER SYNDROME, KLIPPEL-TRENAUNAY-WEBER SYNDROME, AND PORT-WINE STAINS (PWSS) - Compositions and methods for treatment of Sturge-Weber Syndrome, Klippel-Trenaunay-Weber Syndrome, Port-Wine Stains and related neurocutaneous disorders are provided. Cell lines having the somatic mutation GNAQ p.Arg183Gln amino acid substitution, which was found to be the cause of port-wine stains (prevalence 1 in 300) and Sturge-Weber syndrome are also provided. Compositions and methods for treatment of uveal melanoma are also provided herein. Methods of screening novel compounds and compositions useful in increasing RGS2 and/or RGS4 expression and function in vitro, and for treatment of Sturge-Weber Syndrome, Klippel-Trenaunay-Weber Syndrome, Port-Wine Stains and related neurocutaneous disorders are provided are also provided.||11-13-2014|
|20100221250||METHODS OF TREATING BRAIN TUMORS WITH ANTIBODIES - The application is directed toward a method of treating a brain tumor in a patient comprising systemically administering a monoclonal antibody.||09-02-2010|
Patent applications by Kennedy Krieger Institute, Inc.